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US20120121820 |
FABRICATION OF SILK FIBROIN PHOTONIC STRUCTURES BY NANOCONTACT IMPRINTING
A method of manufacturing a nanopatterned biophotonic structure includes forming a customized nanopattern mask on a substrate using E-beam lithography, providing a biopolymer matrix solution,...
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8159288 |
Low power BPSK demodulator
A low power BPSK demodulator having a simple architecture, compact design and reliable is provided. The BPSK demodulator includes a first branch (210) having a first mixer (212) and a first low...
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US20120064518 |
Methods, tip assemblies and kits for introducing material into cells
Methods, tip assemblies and kits are provided for introducing material into cells. The tip assemblies include an attachment portion, a channel portion, and a constriction that function to reduce...
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US20120058117 |
NEUROPILIN-1 INHIBITORS
The present invention relates to molecules interfering with the function of neuropilin-1 in the context of angiogenesis and the treatment of cancer. Molecules, polypeptides, antibodies,...
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8129141 |
Fibrous protein fusions and use thereof in the formation of advanced organic/inorganic composite materials
The claimed invention provides a fusion polypeptide comprising a fibrous protein domain and a mineralization domain. The fusion is used to form an organic-inorganic composite. These...
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US20120035403 |
CONVERTING BIOMASS TO GASEOUS FUEL HYDROCARBONS
A method includes providing a solution containing a C2-6 carboxylic acid or a C2-6 carboxylate that is derived from biomass; and contacting the solution with a solid catalyst to form a C1-5...
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US20120016033 |
Small Molecule Antagonists of Phosphatidylinositol-3,4,5-Triphosphate (PIP3) and Uses Thereof
Disclosed are new members of a class of non-lipid small molecule inhibitors which interfere with the interaction between phosphoinositol-3,4,5-triphosphate (PIP3) and pleckstrin homology (PH)...
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8093217 |
Methods and compositions for inhibition of multi-drug resistance by hyaluronan oligomers
Pharmaceutical compositions and methods for sensitizing multi-drug resistant cancer or radiation resistant cancer cells to chemotherapeutic agents are provided. Compositions include ligands of...
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US20110319398 |
INHIBITION OF YOPS TRANSLOCATION
The disclosure relates to compounds and methods of inhibiting type three secretion system effector molecules, to methods of detecting compounds that inhibit Yops translocation, and to methods of...
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US20110280847 |
METHODS AND COMPOSITIONS FOR INHIBITING CLOSTRIDIUM DIFFICILE SPORE GERMINATION AND OUTGROWTH
Certain bile acids, including novel bile acids, and derivatives thereof can be used to inhibit the germination of C. difficile spores and/or the growth of C. difficile cells. The methods and...
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US20110275788 |
FIBROUS PROTEIN FUSIONS AND USE THEREOF IN THE FORMATION OF ADVANCED ORGANIC/INORGANIC COMPOSITE MATERIALS
The claimed invention provides a fusion polypeptide comprising a fibrous protein domain and a mineralization domain. The fusion is used to form an organic-inorganic composite. These...
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US20110275538 |
MEASUREMENT OF BIOLOGICAL TARGETS
An integrated imaging system, e.g., a microsystem, for detecting activity of a biological target, for example, in response to a stimulus, includes an array of pixels arranged on a substrate, each...
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US20110272348 |
IRON-MEDIATED REMEDIATION WITHIN NONAQUOUS PHASE LIQUID
The present invention relates to remediation of hazardous waste sites. In particular, the present invention relates to compositions and methods for remediation of environmental contaminants in...
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8053387 |
Catalyst having metal in reduced quantity and reduced cluster size
The invention contemplates a method of making a catalytic material, and uses of the material. The catalytic material is made by depositing catalytic metals, such as gold or platinum, on substrate...
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US20110262971 |
Genetically Modified E. coli Strains for Producing Erythromycin
Genetically modified E. coli strains capable of producing erythromycins, particularly erythromycin A.
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US20110172519 |
SYSTEMS, DEVICES AND METHODS EMPLOYING FIBER OPTIC SHAPE TRACKING
The present invention provides systems, devices, and methods employing fiber optic shape and position tracking. The systems, devices, and methods permit measurement of and continuous tracking of...
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US20110152352 |
SMAD PROTEINS CONTROL DROSHA-MEDIATED MIRNA MATURATION
The invention, in some aspects, relates to compositions and methods useful for modulating expression of miRNAs that are regulated by the TGF-β/BMP signaling pathway. In some aspects, the invention ...
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US20110150775 |
GENOMIC APPROACHES TO FETAL TREATMENT AND DIAGNOSIS
The present invention provides systems for developing and/or testing therapies for prenatal diseases and conditions including Down Syndrome. The present invention also provides diagnostic methods...
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US20110138902 |
MEMS MICROPHONE ARRAY ON A CHIP
The present invention relates to microelectromechanical systems (MEMS). In particular, the present invention relates to MEMS arrays for use in acoustics and other applications.
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7962187 |
Optical imaging and oximetry of tissue
Systems and methods are disclosed for detecting at least one region of a sample having an absorption level different from a background level of absorption in the sample by obtaining thicknesses of...
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7960509 |
Fibrous protein fusions and use thereof in the formation of advanced organic/inorganic composite materials
The claimed invention provides a fusion polypeptide comprising a fibrous protein domain and a mineralization domain. The fusion is used to form an organic-inorganic composite. These...
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7959915 |
Inhibitors of extracellular Hsp90
The present invention describes inhibitors of extracellular Hsp90. The inhibition of extracellular Hsp90 leads to a reduction of the invasiveness of the tumor cells. Furthermore, the invention...
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US20110132871 |
SHEAR SENSORS AND USES THEREOF
The present invention relates to shear sensors. In particular, the present invention relates to deformable sensors for measurement of shear forces during chemical mechanical polishing.
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US20110118125 |
NEONATAL SALIVARY GENOMICS
The present invention provides systems for assessing neonatal development and/or conditions by analyzing neonatal saliva RNA. Methods of identifying genes involved in neonatal development and/or...
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US20110110922 |
Wound Healing Peptides and Methods of Use Thereof
Methods and compositions for the treatment of wounds in a mammalian subject are provided. Particularly, novel polypeptides and encoding nucleic acids that stimulate keratinocyte and endothelial...
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US20110104653 |
INTERACTIVE DIGITAL WORKBOOK SYSTEM AND METHOD
A digital workbook program, method, and system include a program interface module configured to communicate with a set of applications and a workbook module configured to generate a digital...
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US20110104200 |
Methods, compositions and kits for vegetative cell-based vaccines and spore-based vaccines
Methods for immunizing a subject to an antigen of an infectious agent, a tumor, or an allergen are provided, using vegetative cytoplasmic expression of the antigen or spore surface display of the...
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US20110076384 |
SYSTEM AND METHOD FOR MAKING BIOMATERIAL STRUCTURES
A system and method for making a biomaterial device includes a support structure providing a shape for a biomaterial device. At least one applicator has a supply of biomaterial solution and is...
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7914769 |
Compounds for treating human papillomavirus
Methods and compositions for treating human papillomavirus infections are described.
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US20110015136 |
humanized model of membrane attack complex (MAC) formation on murine retina and compositions, kits and methods for treatment of macular degeneration
Methods and compositions for treating a subject having age-related macular degeneration (AMD), methods of assaying human macular degeneration (MD), and methods and kits for assaying potential...
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US20110008906 |
Genetic Association of Polymorphisms in Perilipin (PLIN) Gene With Resistance to Weight Loss
Diagnostics and therapeutics for resistance to weight-loss, which are based upon the identification of a subject's PLIN polymorphisms, haplotype and genotype pattern, are described in this invention.
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US20100317570 |
Composition and Method for the Treatment of Diseases Affected by a Peptide Receptor
The present invention includes peptidomimetic compound compositions and methods of making and using peptidomimetic compounds to modulate the activity of a peptide receptor for the treatment of one...
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US20100298540 |
Crystal Structure of a MarR Family Polypeptide
The crystal structure of the product, crystals of the MarR protein, a regulator of multiple antibiotic resistance in Escherichia coli, and methods of crystallization of the MarR protein are described.
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US20100292543 |
Analysis of Endogenous Fluorescence Images to Extract Morphological/Organization Information About Living Samples
Methods and computer program products for analyzing tissue are provided. The tissue is exposed to light at the appropriate wavelengths for inducing fluorescence. Images of the fluorescing tissue...
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US20100286250 |
FLUORINATED LIPIDS AND METHODS OF USE
The invention provides methods and compounds for delivering agents to cells. The compounds can include a fluorinated lipid, a linker, and an agent for delivery to a cell.
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US20100277234 |
Low Power BPSK Demodulator
A low power BPSK demodulator having a simple architecture, compact design and reliable is provided. The BPSK demodulator includes a first branch (210) having a first mixer (212) and a first low...
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US20100272651 |
METHOD FOR ASSESSING POTENTIAL FOR TUMOR DEVELOPMENT AND METASTASIS
The present invention generally provides methods for assessing the potential of tumor formation and/or metastasis using a combination (e.g., a ratio) of the number of circulating tumor cells and...
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US20100261168 |
Screening for Environmental DNAs Encoding Enzymes for Synthesizing Terpenoid-Based Therapeutic Compounds Using Genetically Modified E. Coli Strains
A screening method for identifying microbial genes involved in biosynthesis of therapeutic terpenoid-based compounds using genetically modified E. coli strains that yield high levels of products of...
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US20100247566 |
CHOLERA VACCINES
The methods and compositions of the present invention are directed to a vaccine against Vibrio cholerae comprised of V. cholerae outer membrane vesicles (OMVs). Such vaccines are relatively stable,...
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US20100233421 |
Doubly-Curved Mesh
A doubly-curved mesh (110) is fabricated based on a customized design. In one aspect, a plurality of material-strips (112) are provided. A length is determined for at least one segment (223) of at...
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7797647 |
Circuit having hardware threading
Hardware threading optimizes use of hardware resources in a dynamic workload environment. Unutilized hardware resources are dynamically borrowed to increase throughput performance and/or power...
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US20100211357 |
METHOD FOR MUTLI-STAGE SPATIAL SAMPLING WITH MULTIPLE CRITERIA
The present invention provides a method for implementing a multi-stage spatial sampling strategy to select optimal sampling locations and determine an optimal sampling density for a quantification...
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US20100209447 |
Methods of making and using a cell penetrating peptide for enhanced delivery of nucleic acids, proteins, drugs, and adenovirus to tissues and cells, and compositions and kits
A peptide-POD with ability to penetrate and deliver fluorophores, siRNA, DNA and quantum dots to cells in culture and retinal and ocular tissues in vivo is provided herein. POD couples to...
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US20100208996 |
DEVICES AND METHODS FOR RESTORING LOW-RESOLUTION TEXT IMAGES
A system that extracts text from an image includes a capture device that captures the image having a low resolution. An image segmentation subsystem partitions the image into image segments. An...
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US20100184838 |
Compositions and methods for retinal transduction and photoreceptor specific transgene expression
Adenovirus (Ad) vectors are here provided for treatment of ocular tissues as are suitable methods to transduce photoreceptor (PR) cells, the tissue associated with degeneration. Expression from CMV...
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US20100184081 |
GENETIC MARKERS FOR OBESITY
The present invention is directed to new genetic variants or polymorphisms at the perilipin locus (PLIN) including PLIN1: 6209T (allele 1)>C (allele 2); PLIN3 10171 (allele 1) A >T (allele 2);...
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US20100169038 |
METHODS FOR CALCULATING PARTICLE SIZE DISTRIBUTION
The present invention provides processes employing algorithms and methods for calculating particle size distribution. In particular, the present invention provides processes employing algorithms...
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US20100032547 |
METHOD AND SYSTEM OF ARRAY IMAGING
The present invention relates to a method and system of array imaging that extends or maximizes the longevity of the sensor array by minimizing the effects of photobleaching. The imaging system has...
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US20100004163 |
Composition and Uses of a Galectin for Treatment of Dry Eye Syndrome
Methods for the therapeutic treatment of dry eye in mammals comprising administering to a mammal afflicted with an epithelial wound a therapeutically effective amount of a galectin-1 protein, a...
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US20100003158 |
VIBRATORY POWDER CONSOLIDATION
A vibratory powder consolidation process is provided in which a powder material is subjected to vibratory energy while under static compressive loading. The process provides rapid, full-density...
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