Patents and Patent Applications from Tufts University


Matches 1 - 50 out of 78 1 2 >
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US20100004163 Composition and Uses of a Galectin for Treatment of Dry Eye Syndrome  
Methods for the therapeutic treatment of dry eye in mammals comprising administering to a mammal afflicted with an epithelial wound a therapeutically effective amount of a galectin-1 protein, a...
US20100003158 VIBRATORY POWDER CONSOLIDATION  
A vibratory powder consolidation process is provided in which a powder material is subjected to vibratory energy while under static compressive loading. The process provides rapid, full-density...
7595473 Method and system of array imaging  
The present invention relates to a method and system of array imaging that extends or maximizes the longevity of the sensor array by minimizing the effects of photobleaching. The imaging system has...
US20090232901 POLYMERIC MICROSPHERES  
The invention features core-shell microsphere compositions, hollow polymeric microspheres, and methods for making the microspheres. The microspheres are characterized as having a polymeric shell...
US20090223439 Apparatuses and Methods for Growing Single Crystals  
In some embodiments, an apparatus configured to grow a single crystal includes a support configured to carry the single crystal. The support includes an end portion having variable widths along a...
7556929 Compositions and methods for screening anti-cancer agents in yeast  
Methods and kits for identifying novel anti-tumor agents are provided.
US20090117593 T. Cruzi-derived neurotrophic agents and methods of use therefor  
The invention relates to T. cruzi trans-sialidase (TS) and to the neurotrophic and IL-6 secretion-inducing activities of the protein. TS, neurotrophic variants and/or neurotrophic peptides based...
US20090062685 ELECTRO-OPTICAL SENSOR FOR PERIPHERAL NERVES  
Near-infrared spectroscopy (NIRS) is employed to examine the neuronal activity and vascular response of a peripheral nerve for research or clinical purposes. An embodiment for implementing this...
US20090027398 METHOD FOR RECOGNIZING A SHAPE FROM A PATH OF A DIGITIZING DEVICE  
Described is a method for recognizing a shape from a path of a digitizing device. A set of points along a path of the digitizing device is acquired and a parametric representation is fit to the...
US20090027397 METHOD FOR FITTING A PARAMETRIC REPRESENTATION TO A SET OF OBJECTS GENERATED BY A DIGITAL SKETCHING DEVICE  
Described is a method for sketching with a digitizing device. A set of digitized points along a path of the digitizing device are acquired and a parametric representation is fit to the path....
US20090027396 METHOD FOR FITTING A PARAMETRIC REPRESENTATION TO A SET OF OBJECTS  
Described is a method for fitting a parametric representation to digital data. A vector distance field is generated to represent a set of objects and a parametric representation for the set of...
7480433 Electro-optical stimulation/measurement  
An electro-optical system includes an array including a plurality of optical fibers and a plurality of electrodes, and an insulator. The optical fibers are configured to transmit light, the optical...
US20080306619 Systems And Methods For Synchronizing Music  
The present invention relates to music systems. In particular, the present invention relates to music systems capable of altering the rate of play (e.g., beats per time interval) of a musical piece...
7390634 β-netrin and uses thereof  
β-netrin nucleic acid molecules and polypeptides are provided. Methods of using the β-netrin nucleic acid molecules and polypeptides are also provided.
7381557 Compositions and methods for bacterial immunity and secretion of proteins  
Attenuated strains of Gram negative bacteria carrying a mutation in one or more ysc genes or homologs are provided, as are methods of use for immunization against infection with a pathogenic strain...
US20080093219 Magnetic Protein Nanosensors and Methods of Use  
Nanometer-scale sensors useful in the detection of biological and chemical entities are formed from a protein rod body portion 41 , a magnetic particle 42 affixed to the protein rod body portion...
US20070248959 Genetic markers for obesity  
The present invention is directed to new genetic variants or polymorphisms at the perilipin locus (PLIN) including PLIN1: 6209T (allele 1)>C (allele 2); PLIN3 10171 (allele 1) A>T (allele 2);...
US20070197651 Treatment of stereotypic, self-injurious and compulsive behaviors in man and animals using antagonists of NMDA receptors  
NMDA receptor antagonists can be used in methods of treatment, for reducing the frequency of stereotypic behaviors in animals and for reducing the frequency of analogous compulsive behaviors in...
US20070155957 Crystals of MarR polypeptides, regulators of multiple antibiotic resistance  
The crystal structure of the product, crystals of the MarR protein, a regulator of multiple antibiotic resistance in Escherichia coli , and methods of crystallization of the MarR protein are...
US20070040095 Method and system of array imaging  
The present invention relates to a method and system of array imaging that extends or maximizes the longevity of the sensor array by minimizing the effects of photobleaching. The imaging system has...
US20060289310 PRECISION PARTS BY ELECTROPHORETIC DEPOSITION  
Precision parts and methods for electrophoretic deposition of precision parts from a slurry of fine particles deposited on a removable template, the slurry having a charge-assisting agent and a...
US20060205927 Templated native silk smectic gels  
One aspect of the present invention relates to a method of preparing a fibrous protein smectic hydrogel by way of a solvent templating process, comprising the steps of pouring an aqueous fibrous...
US20060159837 Method for forming inorganic coatings  
The present invention is directed to a method for forming an inorganic coating on a protein template. The method comprises contacting the template with an anionic polymer interface followed by an...
7062385 Intelligent electro-optical nucleic acid-based sensor array and method for detecting volatile compounds in ambient air  
The present invention generally relates to nucleic acid-based sensors and methods for detecting volatile analytes. More particularly, this invention relates to nucleic acid-based optical sensors,...
7047055 Fetal pulse oximetry  
A fetal blood pulse oximetry method and apparatus using a first wavelength of light at about 655 to 705 nm and a second wavelength of light at about 820 to 900 nm. Measurements are taken through a...
US20060073151 Inhibitors of extracellular Hsp90  
The present invention describes inhibitors of extracellular Hsp90. The inhibition of extracellular Hsp90 leads to a reduction of the invasiveness of the tumor cells. Furthermore, the invention...
6999657 High density optical data storage  
A data storage apparatus includes an array of optical fibers. The array has a first end and a second end. The first end of the array includes multiple optical fiber ends, each optical fiber end...
6991939 Optical array device and methods of use thereof for screening, analysis and manipulation of particles  
Methods and devices are provided for the trapping, including optical trapping; analysis; and selective manipulation of particles on an optical array. A multi-channel device parcels a light source...
6985763 Method for measuring venous oxygen saturation  
A method for measuring venous oxygen saturation levels has steps of measuring optical absorption oscillation data at the respiratory frequency at a plurality of wavelengths ( 2 ). A reduced...
US20050260706 Silk biomaterials and methods of use thereof  
The present invention provides an all-aqueous process and composition for production of silk biomaterials, e.g., fibers, films, foams and mats. In the process, at least one biocompatible polymer,...
US20050227219 Method for suppression or reversing of cellular aging  
A method is provided for growing young cells that reduces and/or reverses age-related processes that would otherwise occur in those cells, and also compositions for growing cells in such a method.
6951827 Controlling surface chemistry on solid substrates  
By exposing precursor molecules traveling in a molecular beam to a narrow bandwidth laser beam (hu) tuned to a vibrational resonance frequency of the molecules and aimed orthogonal to the molecular...
6951215 Drug delivery device for animals  
The invention features a drug delivery device which contains a cup-shaped body for enclosing a single external nare of a mammal but does not extend into the nostril of the mammal. The device is...
US20040265340 Emulsan adjuvant immunization formulations and use  
Immunization formulations comprising an antigen and an emulsan or emulsan analog are formed and can be administered to a host. The emulsan or emulsan analog is an adjuvant in the immunization...
US20040101851 Intelligent electro-optical nucleic acid-based sensor array and method for detecting volatile compounds in ambient air  
The present invention generally relates to nucleic acid-based sensors and methods for detecting volatile analytes. More particularly, this invention relates to nucleic acid-based optical sensors,...
6720007 Polymeric microspheres  
The invention features core-shell microsphere compositions, hollow polymeric microspheres, and methods for making the microspheres. The microspheres are characterized as having a polymeric shell...
6706868 Quiescent cell dipeptidyl peptidase: a novel cytoplasmic serine protease  
Disclosed herein are the cDNA and polypeptide sequences of a novel cytoplasmic post-prolyl dipeptidase, QPP. QPP is expressed in T-cells and in neurons, and functions to protect quiescent cells...
6689364 Borrelia burgdorferi polypeptides and uses thereof  
The present invention provides novel polypeptides which are substantially free of a B. burgdorferi spirochete or fragments thereof and which are thus useful in compositions and methods for the...
US20030162754 Use of GABA and GABAB agonists  
The present invention provides methods of stimulating tissue growth, including islet cell growth, by administering GABA or a GABA agonist to act on GABA B receptors and GABA B -like receptors to...
6603658 Laminar air jet cooling of heat producing components  
A low velocity, laminar jet of air is directly impinged on the surface of heat producing components such as a microprocessor chip. A laminar jet air flow has a very low mass flow rate and has a...
US20030068518 Process of forming a composite coating on a substrate  
Precursor-based methods for the production of metal-matrix composite (MMC) coatings on steel and aluminum substrates for improved wear, corrosion and oxidation resistance have been made. Wire and...
6534294 Production of chitosan-and chitin-like exopolymers  
A method of producing biosynthetic copolymers comprising glucose and glucose analogs is provided. Glucose:glucose analog copolymers such as glucose:glucosamine, glucose:N-acetylglucosamine and...
US20030013104 Multiple antibiotic resistance operon assays  
An isolated and cloned region of a bacterial chromosome containing a multiple antibiotic resistance operon is disclosed. A description of the structure and function of the operon is provided as...
6485955 Quiescent cell dipeptidyl peptidase: a novel cytoplasmic serine protease  
Disclosed herein are the cDNA and polypeptide sequences of a novel cytoplasmic post-prolyl dipeptidase, QPP. QPP is expressed in T-cells and in neurons, and functions to protect quiescent cells...
US20020137667 T. cruzi-derived neurotrophic agents and methods of use therefor  
The invention relates to T. cruzi trans-sialidase (TS) and to the neurotrophic and IL-6 secretion-inducing activities of the protein. TS, neurotrophic variants and/or neurotrophic peptides based...
US20020123080 Inhibiting proliferation of cancer cells  
A method of testing cancer cells is described. Assays are provided for determining the potential for inhibiting cancer cells proliferation using albumin-derived peptides. The methods of the present...
6338560 Self-cleaning rotating mirrors  
A self-cleaning, rotating mirror includes a compressor assembly mounted to a cylinder of a rotating mirror. As the cylinder and mirror rotate, the compressor assembly also rotates causing a...
6274305 Inhibiting proliferation of cancer cells  
A method of testing cancer cells is described. Assays are provided for determining the potential for inhibiting cancer cells proliferation using albumin-derived peptides. The methods of the present...
6100234 Treatment of HIV  
A method for increasing immune responses of a human patient infected with HIV, involving contacting the T-cells, in vitro or in vivo, with an organic compound at a concentration effective to cause...
6075058 Compositions for increased bioavailability of carotenoids  
A mixture of 200 micrograms of the carotenoid lutein and 125 micrograms of the carotenoid zeaxanthin, along with the 10 mg of cholesterol, 100 mg olive oil, 20 mg egg yolk phospholipid, 250...
Matches 1 - 50 out of 78 1 2 >