Sign up

Patents and Patent Applications from Stanford University


Match Document Document Title
US20140187519 BIOMARKERS FOR PREDICTING MAJOR ADVERSE EVENTS  
Provided herein are diagnostic markers and uses thereof for predicting if a subject is at risk of a major adverse event. In particular, one aspect provided herein relates to methods to determine if...
8765414 GPCR fusion protein containing an N-terminal autonomously folding stable domain, and crystals of the same  
Certain embodiments provide a GPCR fusion protein. In particular embodiments, the GPCR fusion protein comprises: a) a G-protein coupled receptor (GPCR); and b) an autonomously folding stable...
8765390 Identification and isolation of squamous carcinoma stem cells  
Squamous carcinoma stem cells (SCSC) are identified. The cells can be prospectively isolated or identified from primary tumor samples, and are shown to possess the unique properties of cancer stem...
8765098 Star polymers, methods of preparation thereof, and uses thereof  
A composition of matter comprising an amphiphilic star polymer, the star polymer comprising a crosslinked microgel core and 6 or more independent polymer arms covalently linked to the core, the 6...
US20140179751 Compounds and Compositions That Bind and Stabilize Transthyretin and Their Use for Inhibiting Transthyretin Amyloidosis and Protein-Protein Interactions  
Disclosed herein are compounds and compositions thereof which find use in increasing stability of proteins particularly proteins that tend to misfold and form aggregates. Also provided herein are...
US20140178913 Detection of Molecular Interactions Using a Reduced Affinity Enzyme Complementation Reporter System  
Methods and compositions for detecting molecular interactions are provided. Aspects of the invention include the use of a reduced affinity enzyme complementation reporter system. Also provided are...
US20140178352 PEPTIDE INHIBITORS OF PROTEIN KINASE C  
PKC V5 isozyme-specific peptides are described. The sequences and compositions comprising the sequences are useful for treating disease states associated with the PKC isozyme from which they are...
US20140178022 WAVEGUIDE APPARATUSES AND METHODS  
Optical fiber waveguides and related approaches are implemented to facilitate communication. As may be implemented in accordance with one or more embodiments, a waveguide has a substrate including...
US20140177794 SYSTEM AND METHOD FOR FOCAL SPOT DEFLECTION  
An X-ray tube and methods for imaging are disclosed. The X-ray tube includes an emitter configured to generate an electron beam. Further, the X-ray tube includes a target configured to generate...
US20140174928 METHODS AND APPARATUSES FOR FILTERING WATER FLUID BY SCREENING IONIC MINERALS  
Various aspects of the present disclosure are directed toward apparatus and methods method for filtering water fluid by screening ionic minerals including sodium chloride from the water fluid. In...
8759424 Coated biodegradable building article  
A composite material includes a matrix composed of a polyhydroxyalkanoate (PHA) polymer and a filler composed of particles dispersed in the matrix. The particles are composed of naturally-derived...
8759312 Methods and compositions for reducing viral genome amounts in a target cell  
Methods and compositions for reducing viral genome amounts in a target cell are provided. In the subject methods, the activity of a miRNA is inhibited in a manner sufficient to reduce the amount of...
8758750 Synergistic anti-CD47 therapy for hematologic cancers  
Methods are provided for treatment of hematologic cancers, particularly lymphomas and leukemias, including without limitation myelogenous and lymphocytic leukemias. A combination of antibodies...
US20140171784 Method for 3D motion tracking in an MRI scanner using inductively coupled microcoils  
Wireless markers having predetermined relative positions with respect to each other are employed for motion tracking and/or correction in magnetic resonance (MR) imaging. The markers are...
US20140171410 Batrachotoxin Analogues, Compositions, Uses, and Preparation Thereof  
Compounds relating to batrachotoxin are provided, in particular analogues that modulate the activity of sodium channels. Also provided are pharmaceutical compositions comprising compounds of the...
US20140171356 CHEMICALLY IMMOBILIZED WNT PROTEIN AND METHODS OF USE  
Methods are provided for contacting a target cell with a biologically active Wnt polypeptide that is coupled to a magnetic particle, for producing biologically active bead-coupled Wnt stimulator...
US20140170695 Biological cell nanocavity probes  
An optical fiber is combined with a photonic crystal structure (PCS) that is optically coupled to the optical fiber. The fiber has an exposed fiber surface, and the PCS is affixed to the optical...
8753812 Charge perturbation detection method for DNA and other molecules  
Methods for direct detection of chemical reactions are provided. Electric charge perturbations of the local environment during enzyme-catalyzed reactions are sensed by an electrode system with an...
8753630 Using EGFRvIII to identify and target cancer stem cells  
A set of markers for cancer stem cells are provided. The cells can be prospectively isolated or identified from primary tumor samples, and possess the unique properties of cancer stem cells in...
8753605 Imaging probes, methods of making imaging probes, and methods of imaging  
In accordance with the purpose(s) of the present disclosure, as embodied and broadly described herein, embodiments of the present disclosure, in one aspect, relate to methods of detecting the...
US20140162960 Scaffold-Kinase Interaction Blockades and Uses Thereof in Treating Cancer  
Aspects of the invention include compositions and methods for inhibiting the interaction between scaffold proteins and kinases. These compositions and methods find a number of uses including, for...
US20140161843 Dynamic Macropore Formation Using Multiple Porogens  
Macroporous 3-D tissue engineering scaffold are manufactured by contacting an article comprising multiple distinct macroparticulate porogens distributed within a polymer scaffold, wherein the...
US20140161825 Methods of Treating Acute Myeloid Leukemia by Blocking CD47  
Methods are provided to manipulate phagocytosis of cancer cells, including e.g. leukemias, solid tumors including carcinomas, etc.
US20140161805 Methods for Manipulating Phagocytosis Mediated by CD47  
Methods are provided to manipulate phagocytosis of cells, including hematopoietic cells, e.g. circulating hematopoietic cells, bone marrow cells, etc.; and solid tumor cells. In some embodiments of...
US20140161786 Therapeutic compositions and related methods  
The present invention generally relates to therapeutic compositions for the treatment of mammalian disease and related methods. It more specifically relates to compositions comprising peptides for...
8750652 Microfluidic waveguide detector  
A microfluidic detection device is provided that includes a planar waveguide, or an ion-exchange planar waveguide, a microfluidic channel disposed on the planar waveguide, a light source, such as a...
8748904 Low loss nano-aperture  
Low loss optical apertures are provided. A silicon intermediate layer sandwiched between a metal aperture layer and a dielectric layer has been found to offer a good combination of low optical loss...
8748404 DNA vaccination for treatment of multiple sclerosis and insulin-dependent diabetes mellitus  
A pro-inflammatory T cell response is specifically suppressed by the injection into a recipient of DNA encoding an autoantigen associated with autoimmune disease. The recipient may be further...
8748354 RNA interactome analysis  
A method of sample analysis is provided. In certain cases, the method comprises: a) cross-linking the contents of a cell using a heat stable crosslinking agent to produce cross-linked...
8748338 Polysulfide-rubber-coated activated carbon (PSR-AC) as a multi-sorbent for mercury and polychlorinated biphenyls (PCBS)  
A toxin immobilization particle and method of fabrication is provided that includes a polysulfide-rubber polymer coated activated carbon particle that provides enhanced toxin adsorption. A porous...
US20140155329 Long-Acting Peptide Analogs  
Long-acting agonistic analogs for CLR/RAMP receptors are provided that have an extended half-live in vivo.
US20140154673 PROBES OF RNA STRUCTURE AND METHODS FOR USING THE SAME  
Methods for obtaining structural data from RNA in a sample, and RNA probes for performing the same, are provided. Methods of reversibly modifying RNA is a sample, in vitro or in vivo, and...
8741860 Modulation of T cell signaling threshold and T cell sensitivity to antigens  
MicroRNAs (miRNAs) are a diverse and abundant class of ˜22-nucleotide (nt) endogenous regulatory RNAs that play a variety of roles in animal cells by controlling gene expression at the ...
8741839 Polypeptides targeting vascular endothelial growth factor receptor-2 and αvβ3 integrin  
Polypeptides comprising variant vascular endothelial growth factor sequences are provided. The polypeptides are useful in cancer imaging, cancer diagnosis, monitoring and treatment as well as...
US20140148880 Upconversion of Light for Use in Optogenetic Methods  
Provided herein are compositions comprising lanthanide-doped nanoparticles which upconvert electromagnetic radiation from infrared or near infrared wavelengths into the visible light spectrum. Also...
US20140148351 Prediction of Clinical Outcome in Hematological Malignancies Using a Self-Renewal Expression Signature  
Methods, compositions, and kits are provided for providing a diagnosis, a prognosis, or a prediction of responsiveness to a therapy for a patient with a hematological malignancy. In practicing the...
US20140148346 METHODS OF IDENTIFYING AND CLASSIFYING ORGANOHALIDE-RESPIRING BACTERIA  
Briefly described, embodiments of the present disclosure relate to methods and systems for identifying and classifying taxa of organohalide-respiring bacteria, including methods and systems for...
8735609 Bryostatin analogues, synthetic methods and uses  
Biologically active compounds related to the bryostatin family of compounds, having simplified spacer domains and/or improved recognition domains are disclosed, including methods of preparing and...
8735286 Deposition-free sealing for micro- and nano-fabrication  
A method for sealing through-holes in a material via material diffusion, without the deposition of a sealant material, is disclosed. The method is well suited to the fabrication and packaging of...
8735096 Optical control of protein activity and localization by fusion to photochromic protein domains  
Engineered fusion proteins comprising photochromic protein domains are disclosed. In particular, the inventors have constructed fusion proteins containing photoswitchable photochromic fluorescent...
US20140142437 SYSTEMS AND METHODS FOR MONITORING HEART FUNCTION  
Characteristics of a user's heart are detected. In accordance with an example embodiment, a ballistocardiogram (BCG) sensor is used to detect heart characteristics of a user, and provide a BCG...
US20140141449 Autoantibody Biomarkers for IGA Nephropathy  
Aspects of the present invention include methods for diagnosing and monitoring IgAN in a subject. In practicing one aspect of the subject methods, a sample from a subject is analyzed for the...
US20140141061 Use of WNT Agents to Prevent Hypoxic Injury  
Methods and compositions are provided for the therapeutic use of Wnt proteins or Wnt agonists in protecting tissue from the adverse effects of hypoxia.
US20140140930 NON-PEPTIDIC QUENCHED FLUORESCENT IMAGING PROBES  
Methods and materials for the imaging of cells and tissues containing active proteases such as cathepsin are disclosed. The present materials include activity based probes that bind to an enzyme...
US20140140514 Fully Homomorphic Encryption Method Based On A Bootstrappable Encryption Scheme, Computer Program And Apparatus  
A method includes encrypting information in accordance with an encryption scheme that uses a public key; encrypting a plurality of instances of a secret key, each being encrypted using at least one...
US20140138612 FULLERENE-DOPED NANOSTRUCTURES AND METHODS THEREFOR  
Nanostructures are doped to set conductivity characteristics. In accordance with various example embodiments, nanostructures such as carbon nanotubes are doped with a halogenated fullerene type of...
8731844 System and method for selecting a multiparameter reagent combination and for automated fluorescence compensation  
The invention provides a system and method for selecting an optimal multimarker reagent combination for the identification and/or quantification of molecules in or on cells with or without...
8729486 MODFET active pixel X-ray detector  
Detection of ionizing radiation with modulation doped field effect transistors (MODFETs) is provided. There are two effects which can occur, separately or together. The first effect is a direct...
8729067 Pharmacological treatment of cognitive impairment  
Methods for treating an individual to improve cognitive function are provided. In the subject methods, an effective amount of a noncompetitive GABAA ionophore blocker is administered to the...
8729040 Cell line, system and method for optical control of secondary messengers  
A variety of methods, devices and compositions are implemented for light-activated molecules. One such method is implemented for generating secondary messengers in a cell. A nucleotide sequence for...