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US20120066783 |
AAV CAPSID LIBRARY AND AAV CAPSID PROTEINS
Recombinant adeno-associated viral (AAV) capsid proteins are provided. Methods for generating a library of recombinant adeno-associated viral capsid proteins are also provided.
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US20120062902 |
FIBER OPTIC SENSOR USING A HOLLOW CORE FIBER
An optical sensor includes at least a portion of an optical waveguide having a hollow core generally surrounded by a cladding. The cladding substantially confines a first optical signal and a...
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US20120061242 |
Isotachophoresis having interacting anionic and cationic shock waves
Improved electrophoretic analysis is provided by interaction of anionic and cationic isotachophoresis (ITP) shock waves that propagate toward each other, and analysis of the resulting interaction...
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8131717 |
Scoring documents in a database
A method may include identifying a linked document that is linked to by a group of linking documents; identifying links between the linking documents and the linked document; assigning a weight to...
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8131715 |
Scoring documents in a database
A method may include identifying a group of documents; identifying linking documents that include links to the identified documents; assigning a measure of importance to one or more of the linking...
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8130964 |
Systems and methods for identity-based encryption and related cryptographic techniques
A method and system for encrypting a first piece of information M to be sent by a sender [100] to a receiver [110] allows both sender and receiver to compute a secret message key using...
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8129510 |
Minigene expression cassette
Methods and compositions for expressing a gene or nucleotide sequence of interest are provided. The compositions include an expression cassette that includes a synthetic enhancer, a transthyretin...
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US20120053583 |
METHOD FOR PLASMA-MEDIATED THERMO-ELECTRICAL ABLATION WITH LOW TEMPERATURE ELECTRODE
Described herein are methods and apparatus for cutting a material including biological tissue. The apparatus has a cutting electrode with an elongate cutting portion. A voltage pulse waveform...
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US20120052009 |
Imaging probes, methods of making imaging probes, and methods of imaging
In accordance with the purpose(s) of the present disclosure, as embodied and broadly described herein, embodiments of the present disclosure, in one aspect, relate to methods of detecting the...
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8126884 |
Scoring documents in a linked database
A method assigns importance ranks to nodes in a linked database, such as any database of documents containing citations, the world wide web or any other hypermedia database. The rank assigned to a...
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8125270 |
Frequency offset Cartesian feedback system
An amplifier system providing improved Cartesian feedback is provided. A complex band pass error amplifier is provided. A quadrature up converter is connected to the complex band pass error...
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8124407 |
Circular nucleic acid vectors, and methods for making and using the same
Circular nucleic acid vectors that provide for persistently high levels of protein expression are provided. The circular vectors of the subject invention are characterized by being devoid of...
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8124389 |
Crystal structure of aldehyde dehydrogenase and methods of use thereof
The present disclosure provides a crystal structure of aldehyde dehydrogenase (ALDH) with a modulator of ALDH bound thereto. The present disclosure provides a computer readable medium comprising...
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8123898 |
Methods of bonding optical structures, bonding and silylation of optical structures, bonded optical structures, and silylated bonded optical structures
Methods of bonding optical structures, bonded optical structures, silylated bonded optical structures, and the like, are disclosed.
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US20120046591 |
TREATMENT DEVICES AND METHODS WITH EXTENDING ELEMENTS
Devices, bandages, kits and methods are described that can control or regulate the mechanical environment of a wound to ameliorate scar and/or keloid formation. The mechanical environment of a...
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US20120046586 |
SKIN TREATMENT DEVICES AND METHODS WITH PRE-STRESSED CONFIGURATIONS
Devices, bandages, kits and methods are described that can control or regulate the mechanical environment of a wound to ameliorate scar and/or keloid formation. The mechanical environment of a...
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US20120045828 |
Apparatus for Magnetic Separation of Cells
Described here is an automated robotic device that isolates circulating tumor cells (CTCs) or other biological structures with extremely high purity. The device uses powerful magnetic rods covered...
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US20120043226 |
Blood glucose sensing
An oxidative peak in a cathodic scan is observed in the cyclic voltammetry of glucose at gold electrodes, its peak current density being proportional to glucose concentration in a wide potential...
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8121368 |
3D real-time tracking of human anatomy using combined kV and MV imaging
A medical imaging-based system and method uses both kV and MV images captured during a treatment period for organ motion tracking. 3D geometric locations of internal features are computationally...
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8120533 |
Method and system for deriving location information from utility lines
Location systems and methods are implemented using a variety of arrangements and methods. Using one such system location information is provided in response to a utility-line arrangement...
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8119640 |
Hedgehog pathway antagonists methods of use
The present disclosure provides for compounds, pharmaceutical preparations, kits and methods for the inhibition of the Hh pathway and the alleviation of cancer and developmental disorders...
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8119445 |
Organic semiconductors and growth approaches therefor
Organic semiconductor devices exhibit desirable mobility characteristics. In connection with various example embodiments, a monolayer of methyl-terminated molecules exhibits density characteristics...
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US20120039846 |
HEPATITIS C ANTIBODIES AND USES THEREOF
The present invention provides identification and characterization of conformational epitopes of the envelope protein E2 of the Hepatitis C virus (HCV). The present invention provides a panel of...
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8116366 |
Delayed decision feedback sequence estimator
Disclosed is a delayed decision feedback sequence estimator comprising a delayed decision feedback sequence estimator main unit including DDFSE computing unit group including (L+M) DDFSE computing...
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8115048 |
***WITHDRAWN PATENT AS PER THE LATEST USPTO WITHDRAWN LIST***
Treatment or prevention of scars and/or keloids
Devices, bandages, kits and methods are described that can control or regulate the mechanical environment of a wound to ameliorate scar and/or keloid formation. The mechanical environment of a...
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8114586 |
Prevention and treatment of HCV infection employing antibodies directed against conformational and linear epitopes
Conformational epitopes of the envelope proteins E1 and E2 of the Hepatitis C virus (HCV) have been identified and characterized using a panel of monoclonal antibodies derived from patients...
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8112142 |
Assessing the condition of a joint and devising treatment
Methods are disclosed for assessing the condition of a cartilage in a joint, particularly in a human knee. The methods include converting an image such as an MRI to a three dimensional map of the...
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8108333 |
System and method for computing cumulative densities of data represented by gaussian distributions
Probability densities are calculated. According to an example embodiment, a Gaussian probability density is computed for a set of data representing a multivariate Gaussian distribution (Gaussian)...
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8105363 |
Spinal implant and method for restricting spinal flexion
A spinal implant system for restricting flexion of a spine includes an elongate band proportioned to engage at least two spinous processes. During use, the band is positioned engaging the spinous...
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8105324 |
Methods and devices for the non-thermal, electrically-induced closure of blood vessels
Methods and devices for the non-thermal, electrically-induced temporary or permanent closure of blood vessels. The subject methods and devices employ pulsed electrical energy according to a defined...
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US20120021414 |
DIAGNOSTIC MARKERS OF IMMUNOSENESCENCE AND METHODS OF USE THEREOF
Embodiments of the present invention provide diagnostic markers of immunosenescence and methods of identifying individuals with impaired immune function based on a combination of such markers...
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US20120020914 |
LEUKEMIA INHIBITORY FACTOR (LIF) FOR USE IN REPRESSING HUMAN PAPILLOMAVIRUS (HPV) TRANSCRIPTION
Embodiments of the invention are related to leukemia inhibitory factor (LIF) for use in repressing human papillomavirus (HPV) transcription. Processes and related kits are described for treating a...
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US20120019712 |
IMAGING ARRANGEMENTS AND METHODS THEREFOR
Image data is processed to facilitate focusing and/or optical correction. According to an example embodiment of the present invention, an imaging arrangement collects light data corresponding to...
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US20120019711 |
IMAGING ARRANGEMENTS AND METHODS THEREFOR
Image data is processed to facilitate focusing and/or optical correction. According to an example embodiment of the present invention, an imaging arrangement collects light data corresponding to...
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8101169 |
Ocular gene therapy using avalanche-mediated transfection
The present invention provides a method of treating an ocular disease in a subject. In a first step, a nucleic acid is introduced into cells or a tissue. The nucleic acid is introduced by electron...
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8100900 |
System for delivering therapy
The system of the preferred embodiments includes a first rotational element, a second rotational element, and a therapeutic source coupled to the rotational elements. The system permits...
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US20120016325 |
REDUCED PRESSURE THERAPY DEVICES
Described generally herein are tissue therapy devices, which may comprise a sealant layer and a suction apparatus. The sealant layer functions so as to create a sealed enclosure between it and the...
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8099156 |
Cochlear optical analysis system and approach therefor
A micro-optical probe approach facilitates imaging, testing and/or analysis of cochlear tissue. According to an example embodiment, a probe is implanted into cochlear tissue of a live being and...
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US20120009501 |
METHODS OF MANUFACTURING PROTON CONDUCTIVE SOLID OXIDE FUEL CELL AND PROTON CONDUCTIVE SOLID OXIDE FUEL CELLS MANUFACTURED BY USING THE METHODS
A method of manufacturing a proton conductive solid oxide fuel cell, the method including: forming a metallic mask layer having nanoholes on a first surface of a substrate; selectively etching the...
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8094983 |
Multiple-core optical fiber with couplings between the cores
An optical fiber includes a cladding, a first core, and a second core. At least one of the first core and the second core is hollow and is substantially surrounded by the cladding. At least a...
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8093353 |
Agents for treatment of HCV and methods of use
An amphipathic helix at the approximate N-terminus of Hepatitis C virus (HCV) nonstructural proteins mediates the association of these proteins with cytoplasmic membranes in infected cells. This...
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US20120004283 |
NOVEL SHRNA GENE THERAPY FOR TREATMENT OF ISCHEMIC HEART DISEASE
Short hairpin RNA (shRNA) interference therapy targeting hypoxia inducible factor—lot (HIF-1 α) prolyl-4-hydroxylase protein (HIF-PHD2) is used for treatment of myocardial ischemia. This tr...
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US20120004278 |
LINC RNAS IN CANCER DIAGNOSIS AND TREATMENT
Long non-coding RNAs (lincRNAs), a relatively recently recognized class of widely transcribed genes, are thought to affect chromatin state and epigenetic regulation, but their mechanisms of action...
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US20110319405 |
Treatment and prevention of diffuse parenchymal lung disease by selective active-site mTOR inhibitors
Embodiments are related to new uses for selective active-site mTOR inhibitors in treating or preventing pulmonary fibrosis in diffuse parenchymal lung disease (DPLD) patients, such as a DPLD of...
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US20110319272 |
Noninvasive Diagnosis of Fetal Aneuploidy by Sequencing
Disclosed is a method to achieve digital quantification of DNA (i.e., counting differences between identical sequences) using direct shotgun sequencing followed by mapping to the chromosome of...
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US20110317167 |
APPARATUS FOR MEASURING A FREQUENCY-DOMAIN OPTICAL COHERENCE TOMOGRAPHY POWER SPECTRUM FROM A SAMPLE
An apparatus is provided for measuring a frequency-domain optical coherence tomography power spectrum from a sample. The apparatus includes a partially reflective element configured to be optically...
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8084371 |
Field effect transistors, methods of fabricating a carbon-insulating layer using molecular beam epitaxy and methods of fabricating a field effect transistor
Field effect transistors, methods of fabricating a carbon insulating layer using molecular beam epitaxy and methods of fabricating a field effect transistor using the same are provided, the methods...
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8084245 |
Apparatus and method for polymer synthesis using arrays
A polymer synthesis apparatus (20) for building a polymer chain including a head assembly (21) having an array of nozzles (22) with each nozzle coupled to a reservoir (23) of liquid reagent (24),...
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8084087 |
Fabrication method of size-controlled, spatially distributed nanostructures by atomic layer deposition
A method of growing spatially-separated and size-controlled particles on substrate surfaces is provided. The method utilizes chemical modification of the substrate surface, an atomic layer...
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US20110313681 |
BIOMARKERS FOR PERIPHERAL ARTERY DISEASE
This invention provides biomarkers whose concentrations in blood plasma are associated with the presence or absence of PAD in the patient from whom the plasma sample is taken. The invention also...
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