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Patents and Patent Applications from Stanford University


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8637639 Method and composition for crystallizing G protein-coupled receptors  
Certain embodiments provide a method for crystallizing a GPCR. The method may employ a fusion protein comprising: a) a first portion of a G-protein coupled receptor (GPCR), where the first portion...
US20140024701 Compositions and Methods for Treating Neurogenic Disorders of the Pelvic Floor  
Provided herein are methods for the treatment of bladder dysfunction, including detrusor hyperreflexia and detrusor external sphincter dyssynergia, fecal incontinence, and/or sexual dysfunction in...
US20140024649 Substituted Benzamides and Their Uses  
Provided herein are Substituted Benzamides, compositions, and method of their manufacture and use.
US20140021907 Wireless energy transfer  
Electromagnetic energy transfer is facilitated. In accordance with an example embodiment, a first resonator transmits electromagnetic energy using an electromagnetic wave, based on frequency...
8633699 Techniques for determining physical properties of underground structures using lightning  
A method and apparatus includes detecting lightning induced electromagnetic pulses and determining a physical property of an underground structure based on the lightning induced electromagnetic...
8633573 Strained semiconductor materials, devices and methods therefore  
Various applications are directed to a material stack having a strained active material therein. In connection with an embodiment, an active material (e.g. a semiconductor material) is at least...
8632064 Positioning apparatus with lockable joints and method of use  
A positioning system having a base, a manually movable end effector and a first joint interposed between the base and the end effector is disclosed. The first joint may comprise a proximal portion...
US20140017322 SUPRAMOLECULAR FUNCTIONALIZATION OF GRAPHITIC NANOPARTICLES FOR DRUG DELIVERY  
Disclosed are nanoparticles, such as carbon nanotubes or other graphitic sheet materials having extended aromatic surfaces, which are used to deliver active agents such as drugs, labels or dyes...
US20140014515 Enhanced Isotachophoresis Assays Using Additives with Spatial Gradients  
Techniques for enhanced isotachophoresis assays using additives with spatial gradients include forming a concentration gradient of an additive along a channel from an input port to an output port....
8630710 Implanted cardiac device for defibrillation  
An implantable medical device for delivering electrical cardiac therapy includes a first implantable housing containing a battery. There is also a second implantable housing separate from the first...
8630422 Fully homomorphic encryption method based on a bootstrappable encryption scheme, computer program and apparatus  
A method includes encrypting information in accordance with an encryption scheme that uses a public key; encrypting a plurality of instances of a secret key, each being encrypted using at least one...
8629353 Apparatus and method using patterned array with separated islands  
Aspects of the disclosure are directed to an apparatus that is used to provide a circuit layer via a supportive substrate or material layer having an upper surface and having edge surfaces...
8628574 Systems and methods for posterior dynamic stabilization of the spine  
Devices, systems and methods for dynamically stabilizing the spine are provided. The devices include an expandable spacer having an undeployed configuration and a deployed configuration. The spacer...
US20140011755 Cardiac Glycosides for Treating Autoimmune Disease  
The invention provides methods for treating inflammatory and autoimmune diseases by administering to the subject an effective amount of a cardiac glycoside, where the dose is effective to suppress...
US20140011690 Scalable Bio-Element Analysis  
A method is provided for detecting one or more analytes in a sample. The method relies, in part, on the ability of functionalized particles added to the sample to partially or completely inhibit...
US20140010757 IMAGING METHODS USING ENGINEERED INTEGRIN BINDING PEPTIDES  
Engineered peptides that bind with high affinity (low equilibrium dissociation constant (Kd)) to the cell surface receptors of fibronectin (α5β1) or vitronectin (αvβ3 and αvβ5 integrins) are discl...
US20140008542 Methods and Systems for increasing the sensitivity of simultaneous multi-isotope positron emission tomography  
Positron emission tomography (PET) systems suitable for use with dirty (positron+prompt gamma) emitters are provided. One or more prompt gamma detectors are added to the PET system, where the...
US20140006926 SYSTEMS AND METHODS FOR NATURAL LANGUAGE PROCESSING TO PROVIDE SMART LINKS IN RADIOLOGY REPORTS  
Certain examples provide systems, apparatus, and methods to facilitate automated processing of report text to associate text with external content to be accessed via the report. An example method...
US20140004556 Methods for Generating Inner Ear Cells in Vitro  
Methods, compositions and kits are provided for generating inner ear cells in vitro. These methods find use a number of applications, such as in preparing inner ear cells for in vitro screening for...
US20140004050 SELF-QUENCHING ACTIVATABLE COX-2-SPECIFIC MULTI-MODAL MOLECULAR PROBES FOR DIAGNOSIS OF CANCERS, INFLAMMATION, AND IMMUNE SYSTEM DISORDERS  
Encompassed are pharmaceutically acceptable compositions formulated for the topical or transdermal delivery of probes specific for cyclooxygenase-2 (COX-2) of human and non-human subjects. In...
US20140004049 NANOPROBES FOR SENSING OF REACTIVE OXYGEN AND REACTIVE NITROGEN SPECIES  
For whole animal in-situ and real-time imaging of inflammation, a dual-color fluorescent nanoprobe is provided for the detection of reactive oxygen and nitrogen species (RONS) in inflammatory...
US20140001437 JOINED NANOSTRUCTURES AND METHODS THEREFOR  
Nanostructures are joined using one or more of a variety of materials and approaches. As consistent with various example embodiments, two or more nanostructures are joined at a junction between the...
8619358 Electrically pumped extrinsic semiconductor optical amplifier with slot waveguide  
An optical amplifier on a silicon platform includes a first doped device layer and a second doped device layer. A gain medium is positioned between the first and second doped device layers. The...
8618521 Pluridirectional very high electron energy radiation therapy systems and processes  
A compact high-gradient, very high energy electron (VHEE) accelerator and delivery system (and related processes) capable of treating patients from multiple beam directions with great speed, using...
8618254 Inhibition of AXL signaling in anti-metastatic therapy  
Compositions and methods are provided for alleviating cancer in a mammal by administering a therapeutic dose of a pharmaceutical composition that inhibits activity of AXL protein activity, for...
8617624 Compositions, systems and methods for the diagnosis, prevention and treatment of disorders associated with azetidine-2-carboxylic acid  
Methods and systems for detecting azetidine-2-carboxylic acid (Aze) in food consumable by humans and animals are provided. Also provided are methods and systems for inactivating Aze in food and...
8616216 Patterned laser treatment  
Patterned laser treatment of the retina is provided. A visible alignment pattern having at least two separated spots is projected onto the retina. By triggering a laser subsystem, doses of laser...
US20130347137 Stabilized Step Function Opsin Proteins and Methods of Using the Same  
Provided herein are compositions comprising non-human animals comprising neurons expressing stabilized step function opsin proteins on neural plasma membranes and methods of using the same to...
US20130345232 METHODS AND COMPOSITIONS FOR TREATING A SUBJECT FOR A LYMPHATIC MALFORMATION  
Methods of treating lymphatic malformations using a phosphodiesterase type 5 inhibitor are provided. Pharmaceutical compositions and kits comprising phosphodiesterase type 5 inhibitors are also...
US20130344679 ENVIRONMENTALLY-ASSISTED TECHNIQUE FOR TRANSFERRING DEVICES ONTO NON-CONVENTIONAL SUBSTRATES  
A device fabrication method includes: (1) providing a growth substrate including a base and an oxide layer disposed over the base; (2) forming a metal layer over the oxide layer; (3) forming a...
US20130344003 IMMUNO-THERAPY FOR CANCER TREATMENT USING IRON OXIDE NANOPARTICLES  
An immuno-therapy for treatment of a tumor is provided. An effective dose of a composition containing a low dose of superparamagnetic iron oxide nanoparticle is administered to a tumor. Once the...
US20130343998 Control and Characterization of Memory Function  
Provided herein are devices and methods for reversibly controlling memory function in living non-human animals. Some variations of methods for affecting memory function comprise temporarily...
US20130343159 Determining Location Information of Microseismic Events During Hydraulic Fracturing  
A method of determining locations of microseismic events caused by a hydrofracking process is disclosed. The method includes: measuring audio signals using an array of geophones deployed in a...
US20130340232 METHOD OF FABRICATING AN OPTICAL-FIBER-COMPATIBLE SENSOR  
A method for fabricating a sensor is provided, with the sensor including a reflective element and an optical fiber positioned relative to the reflective element such that light emitted from the...
8614305 Nonviral gene delivery vector iopamidol, protamine, ethiodized oil reagent (VIPER)  
Embodiments are related to nonviral gene delivery vectors using only FDA-approved components: iopamidol, protamine, and ethiodized oil.
8614056 Microfluidic method for measurement or detection involving cells or biomolecules  
Embodiments of the invention are related to microfluidic devices for detecting or determining the concentration of biomolecules in an analyte comprising: a channel, wherein a surface of said...
US20130338233 METHODS FOR MICROBIAL BIOFILM DESTRUCTION  
Compositions and methods for the dissolution of a microbial biofilm are provided, where the method comprises contacting a microbiofilm with an effective dose of a curcumin derivative as a biofilm...
8611670 Intelligent part identification for use with scene characterization or motion capture  
A variety of methods, systems, devices and arrangements are implemented for use with motion capture. One such method is implemented for identifying salient points from three-dimensional image data....
8608697 Insertion indicator for needle  
A method and apparatus are provided for a fluid level insertion indicator that provides immediate feedback to a surgeon by draining when a tip of a needle has entered a body lumen, such as...
US20130332315 METHOD AND RELATED APPARATUS FOR GENERATING ONLINE AND PRINTING ON-DEMAND COMPILATION OF WORKS WITH CUSTOMER SELECTABLE PRINTING OPTIONS  
A method and related computer program product for customizing price-related options for printing a compilation of works, including the steps of: compiling the compilation of works; setting...
US20130331646 APPARATUS, SYSTEMS, AND METHODS FOR PERFORMING LAPAROSCOPIC SURGERY  
Apparatus, systems, and methods for laparoscopic abdominal surgery are disclosed. For example, a system or kit is provided for performing a procedure within a surgical space within a patient's body...
US20130331441 Cell Line, System and Method for Optical Control of Secondary Messengers  
A variety of methods, devices and compositions are implemented for light-activated molecules. One such method is implemented for generating secondary messengers in a cell. A nucleotide sequence for...
US20130331330 METHODS OF TREATING ALZHEIMER'S DISEASE AND OTHER TAUOPATHIES WITH INHIBITORS OF MICROTUBULE AFFINITY REGULATING KINASE  
Methods of treating Alzheimer's disease and other tauopathies are disclosed. In particular, the invention relates to methods of treating Alzheimer's disease and other tauopathies with inhibitors of...
US20130330816 Apparatus and Methods for Controlling Cellular Development  
According to one aspect and example, a method for facilitating cellular interactions in biological tissue provides controllable activation of a selected type of stem cell among a plurality of cell...
US20130330559 DOPING OF CARBON-BASED STRUCTURES FOR ELECTRODES  
Various aspects of the present disclosure are directed toward carbon-based electrodes. The carbon-based electrodes include a composition of carbon-based structures treated with an oxide material....
US20130330294 Serum Amyloid A (SAA) Overrides Regulatory T Cells (TREG) Anergy  
Methods and compositions are provided for inducing the proliferation of regulatory T cells. These methods find a number of uses, including, for example, treating autoimmune and rheumatoid diseases....
US20130328684 SYSTEM AND METHOD FOR DETECTING AND PREVENTING DROWSINESS  
A system for preventing drowsiness in a driver by employing a thermal grill. The system includes a detection module and an intervention module. The detection module monitors a driver's parameters...
8603790 Systems, methods and compositions for optical stimulation of target cells  
Methods, systems and devices are implemented in connection with light-responsive ion channel molecules. One such method is implemented using a light-activated ion channel molecule that responds to...
US20130324878 Method of Sonifying Brain Electrical Activity  
A digital processor system having one or more processors and memory obtains a time-domain signal representing brain activity, the time-domain signal having a time varying signal value. The system...
US20130324707 SYNTHETIC AMPHIPHILES FOR MEMBRANE PROTEIN MANIPULATION  
The invention provides amphiphilic compounds and methods for manipulating membrane proteins. Compounds of the invention, for example, the compounds of Formulas I-XIX, can be prepared from readily...