Patents and Patent Applications from Stanford University


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9090627 Batrachotoxin analogues, compositions, uses, and preparation thereof  
Compounds relating to batrachotoxin are provided, in particular analogs that modulate the activity of sodium channels. Also provided are pharmaceutical compositions comprising compounds of the...
US20150206657 Integrated Magnetic Devices with Multi-Axial Magnetic Anisotropy  
A method of fabricating in-plane or out-of-plane thin-film multi-axial magnetic anisotropy devices is provided that includes either depositing a magnetic material with perpendicular or partially...
US20150203545 METHODS FOR TREATING PSYCHIATRIC DISORDERS OR SYMPTOMS THEREOF USING NCAM PEPTIDE MIMETICS  
The present invention provides methods for treating or alleviating one or more symptoms of depression and/or anxiety in a subject comprising administering an effective amount of an NCAM peptide...
US20150201832 METAMORPHOPSIA TESTING AND RELATED METHODS  
A visual distortion test is disclosed using a sequence of binary interactions with a mobile device, in which segments of the grid having no distortions are eliminated, and the segments with...
9087995 Fullerene-doped nanostructures and methods therefor  
Nanostructures are doped to set conductivity characteristics. In accordance with various example embodiments, nanostructures such as carbon nanotubes are doped with a halogenated fullerene type of...
9087241 Intelligent part identification for use with scene characterization or motion capture  
A variety of methods, systems, devices and arrangements are implemented for use with motion capture. One such method is implemented for identifying salient points from three-dimensional image...
9086098 Anti-twist joint, orienting system and method  
A positioning system is provided for orienting a payload. The system may continuously orient the payload relative to another object without twisting connections of the payload. The positioning...
9085570 Substituted benzamides and their uses  
Provided herein are Substituted Benzamides, compositions, and method of their manufacture and use.
9085536 Aconitine compounds, compositions, uses, and preparation thereof  
Compound derivatives of aconitine are provided, in particular derivatives that modulate the activity of sodium channels. Also provided are pharmaceutical compositions comprising compounds of the...
9085458 Selective nanotube formation and related devices  
Nanotube electronic devices exhibit selective affinity to disparate nanotube types. According to an example embodiment, a semiconductor device exhibits a treated substrate that selectively...
9084885 Methods, systems and devices for optical stimulation of target cells using an optical transmission element  
Stimulation of target cells using light, e.g., in vivo, is implemented using a variety of methods and devices. In one such device, target cells are stimulated using an implantable device. The...
9084594 Methods for the prevention of surgical site infections  
Several methods to reduce surgical site infections include inserting a surgical access device into an incision, retracting tissue, and introducing fluid into the surgical access device such that...
US20150197870 Method for Plating Fine Grain Copper Deposit on Metal Substrate  
A method of depositing an oxygen-free electronic copper layer on a metal substrate is provided that includes cleaning a substrate surface, electropolishing the substrate surface activating the...
US20150197844 Depositing Calcium Fluoride Template Layers for Solar Cells  
A biaxially textured crystalline layer formed on a substrate using ion beam assisted deposition (IBAD) is provided. The biaxially textured crystalline layer includes an oriented CaF2 crystalline...
US20150196917 METHODS AND APPARATUS FOR NUCLEIC ACID SYNTHESIS USING OLIGO-TEMPLATED POLYMERIZATION  
A method and apparatus for synthesizing nucleic acid (NA) by sequential addition of nucleotide triphosphates to a single stranded NA molecule (growing-chain) is described. The growing-chain is...
9080176 Multimodality imaging of reporter gene expression using a novel fusion vector in living cells and animals  
Novel double and triple fusion reporter gene constructs harboring distinct imagable reporter genes are provided, as well as applications for the use of such double and triple fusion constructs in...
9079940 Light-sensitive ion-passing molecules  
Disclosed are polynucleotides and methods for expressing light activated proteins in animal cells and altering an action potential of the cells by optical stimulation. The disclosure also provides...
9079859 Synthetic lethal targeting of glucose transport  
The present invention provides methods for inhibiting growth and proliferation of HIF pathway proficient cells by administering GLUT1 inhibitors of the invention to HIF pathway proficient cells.
US20150194720 Compact Waveguide Circular Polarizer  
A multi-port waveguide is provided having a rectangular waveguide that includes a Y-shape structure with first top arm having a first rectangular waveguide port, a second top arm with second...
US20150191753 METHODS FOR CONTROL OF FLUX IN METABOLIC PATHWAYS THROUGH ENZYME RELOCATION  
Genetically manipulated cells, lysates of such cells, systems, and methods of use thereof are provided, where one or more enzymes in a pathway of interest are genetically modified to incorporate a...
US20150191717 SIMULTANEOUS EXTRACTION AND SEPARATION OF RNA AND DNA FROM SINGLE CELLS USING ELECTROPHORETIC TECHNIQUES  
Devices and methods for preparing RNA and DNA from single cells are disclosed. In particular, the invention relates to a method of simultaneously extracting RNA and DNA from single cells and...
US20150191489 IMIDAZO BICYCLIC IMMINIUM COMPOUNDS AS ANTITUMOR AGENTS  
Compounds of formula I: are disclosed. The compounds are inhibitors of Hedgehog pathway activation and are useful in treating solid tumors. An example of such a compound is:
9075010 Enhancement of molecular emission using optical-antenna structures  
The present disclosure relates to an apparatus, and methods of use, for enhancement of molecular emission by nano-antennas. Using the nano-antennas, the life-time is greatly shortened or the...
9074192 Inhibition of AXL signaling in anti-metastatic therapy  
Compositions and methods are provided for alleviating cancer in a mammal by administering a therapeutic dose of a pharmaceutical composition that inhibits activity of AXL protein activity, for...
9073964 Inhibitors of atypical protein kinase C and their use in treating hedgehog pathway-dependent cancers  
Methods and compositions are provided for modulating Hedgehog (Hh) pathway signaling in a cell. Aspects of the methods include methods for inhibiting Hh pathway-promoted cancer proliferation...
9072894 Method and apparatus for radioablation of regular targets such as sympathetic nerves  
Techniques for radioablation of sympathetic nerves include positioning a subject on a support in view of a volume imaging system and an ionizing radiation source; and collecting volume image data....
9072746 Method for enhancing learning and memory impaired by neurodegenerative disorders and compounds and compositions for effecting the same  
A method for enhancing learning or memory of both in a mammal having impaired learning or memory of both from a neuro-degenerative disorder, which entails the step of administering at least one...
9072730 Method of improving cognitive functions in individuals with down syndrome and/or alzheimer's disease  
A method of treating an individual having Down syndrome or Alzheimer's disease, which entails the step of administering an amount of one or more compounds to the individual which improve cognitive...
9072660 Topical itraconazole formulations and uses thereof  
Methods of transdermally delivering a therapeutic amount of a triazole-triazolone compound are provided, e.g. for the prevention or treatment of basal cell carcinoma (BCC) in a subject. A...
US20150186827 Data-driven targeting of energy programs using time-series data  
A method for enrolling utility customers in utility demand response or energy efficiency programs based on time-series consumption data includes collecting from smart meter sensors time-series...
US20150184131 Enhanced Efficiency of Induced Pluripotent Stem Cell Generation  
Human somatic cells are reprogrammed to become induced pluripotent stem cells (iPS cells) by the introduction of a minicircle DNA vector. Cells of interest include adipose stem cells.
US20150183874 HUMANIZED AND CHIMERIC MONOCLONAL ANTIBODIES TO CD47  
Humanized or chimeric anti-CD47 monoclonal antibodies are provided. The antibodies bind to and neutralize human CD47, and find use in various therapeutic methods. Preferred are non-activating...
US20150182511 MODULATORS OF ALDEHYDE DEHYDROGENASE ACTIVITY AND METHODS OF USE THEREOF  
The present invention provides compounds that function as modulators of aldehyde dehydrogenase activity; and pharmaceutical compositions comprising the compounds. The present invention provides...
US20150182506 Modulators of Aldehyde Dehydrogenase and Methods of Use Thereof  
The present disclosure provides compounds that function as modulators of aldehyde dehydrogenase (ALDH) enzymatic activity, as well as compositions and formulations comprising the compounds. The...
9070881 Method of manufacturing an organic semiconductor thin film  
A method of manufacturing an organic semiconductor thin film includes coating an organic semiconductor solution on a substrate, and shearing the organic semiconductor solution in a direction that...
9069089 Methods and systems for increasing the sensitivity of simultaneous multi-isotope positron emission tomography  
Positron emission tomography (PET) systems suitable for use with dirty (positron+prompt gamma) emitters are provided. One or more prompt gamma detectors are added to the PET system, where the...
9068224 Measurement and monitoring of cell clonality  
Methods are provided for the detection and analysis of clonality in a cell population, where parallel sequencing is applied to a nucleic acid sample obtained from the cell population, optionally a...
US20150174202 Methods and Compositions for Modulating Beta Cell Proliferation  
Methods and compositions are provided for modulating pancreatic islet β cell proliferation. Aspects of the methods include promoting β cell proliferation by providing agents that promote PDGFR...
US20150174167 THERAPEUTIC USES OF ALLOGENEIC MYELOID PROGENITOR CELLS  
Myeloid function is enhanced by transplantation or infusion of allogeneic myeloid progenitor cells, including CMP, GMP, MEP and MKP cell subsets. Myeloid progenitors ameliorate sequelae of anemia...
US20150174150 Compositions and Methods for Treating Alzheimer's Disease and Other Tauopathies  
Compounds, pharmaceutical compositions, and methods of using such compounds and compositions to treat or prevent Alzheimer's disease and related tauopathies through the inhibition of USP-9X and/or...
9063573 Method and system for touch-free control of devices  
The present invention provides a system and computerized method for receiving image information and translating it to computer inputs. In an embodiment of the invention, image information is...
9062351 Diagnostic, prognostic and therapeutic uses of long non-coding RNAs for cancer and regenerative medicine  
Long non-coding RNAs (lncRNAs) and methods of using them diagnostically and therapeutically for treatment of cancer, stem cell therapy, or regenerative medicine are disclosed. In particular, the...
9062340 Process for the selection of PHB-producing methanotrophic cultures  
A method of selection for type II methanotrophs is provided that includes enriching a microbial feedstock using a non-sterile bioreactor with a methane source and a nitrogen source, where the...
9061902 Crystalline-amorphous nanowires for battery electrodes  
Electrodes, batteries, methods for use and manufacturing are implemented to provide ion-based electrical power sources and related devices. Consistent with one such method, a battery electrode is...
9061010 Methods of treating a Flaviviridae family viral infection and compositions for treating a Flaviviridae family viral infection  
Briefly described, embodiments of this disclosure include compositions, pharmaceutical compositions, methods of treating a host infected with a virus from the Flaviviridae family of viruses,...
US20150168570 Spectral Imaging System and Method  
Spectral x-ray imaging using a photon counting x-ray detector (PCXD) transmits a broad spectrum x-ray beam through an object, detects the transmitted x-ray beam with the PCXD and processes the...
US20150167048 BETA-LACTAMASE SUBSTRATES AND METHODS OF THEIR USE FOR THE DIAGNOSIS OF TUBERCULOSIS  
β-Lactamase substrates and methods for using the substrates to detect β-lactamase diagnose tuberculosis.
US20150165227 Light-Activated Cation Channel and Uses Thereof  
The present invention provides compositions and methods for light-activated cation channel proteins and their uses within cell membranes and subcellular regions. The invention provides for...
US20150164896 TARGETING A NON-CANONICAL NOTCH SIGNALING PATHWAY FOR CANCER TREATMENT  
Methods and compositions are provided for treating an individual having cancer. Aspects of the methods include administering to the individual an inhibitor of a non-canonical Notch signaling...
9057673 Method of preparing RNA from ribonuclease-rich sources  
Methods for preparing RNA from ribonuclease-rich sources while avoiding RNA degradation are described. The lysis protocol for ribonuclease-containing samples is performed at high pH to accelerate...