Patents and Patent Applications from Stanford University


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9244179 Time-based digitizer for PET photodetector  
An integrated circuit in a PET imaging system with a plurality of photo detectors is provided. A plurality of differential transimpedance amplifiers with differential inputs and differential...
9243282 Droplet-based pyrosequencing  
The present invention relates to droplet-based pyrosequencing including a method of identifying a base at a target position in a sample nucleic acid. The method includes: (a) providing a droplet...
9243232 Inhibitors of mitochondrial fission and methods of use thereof  
The present disclosure provides peptides and constructs that inhibit mitochondrial fission, and compositions comprising the peptides or constructs. The present disclosure provides methods of...
9242274 Pre-charged CMUTs for zero-external-bias operation  
Capacitive micromachined ultrasonic transducers (CMUTs) having a pre-charged floating electrode are provided. Such CMUTs can operate without an applied DC electrical bias. Charge can be provided...
9242273 Method for operating CMUTs under high and varying pressure  
Capacitive micromachined ultrasonic transducers (CMUTs) in permanent contact mode are provided. Such a CMUT always has its plate in contact with the substrate, even for zero applied electrical...
9241972 Use of Wnt agents to prevent hypoxic injury  
Methods and compositions are provided for the therapeutic use of Wnt proteins or Wnt agonists in protecting tissue from the adverse effects of hypoxia.
US20160019994 High Density Grids  
An X-ray data collection grid device is provided that includes a magnetic base that is compatible with robotic sample mounting systems used at synchrotron beamlines, a grid element fixedly...
US20160017435 Differential Methylation Level of CpG Loci That Are Determinative of a Biochemical Reoccurrence of Prostate Cancer  
The present disclosure provides for and relates to the identification of novel biomarkers for diagnosis and prognosis of prostate cancer or the biochemical reoccurence of prostate cancer. The...
US20160017420 METHODS FOR PROFILING AND QUANTITATING CELL-FREE RNA  
The invention generally relates to methods for assessing the health of a tissue by characterizing circulating nucleic acids in a biological sample. According to certain embodiments, methods for...
US20160015265 Implantable Micro-Fluidic Device for Monitoring of Intra-Ocular Pressure  
Glaucoma is the second most common cause of blindness in the global world. It is a multifactorial disease with several risk factors, of which intraocular pressure (IOP) is the most important. IOP...
9238670 Aminoglycoside antibiotics with reduced ototoxicity  
This disclosure relates generally to aminoglycoside derivatives of Formula (I) as described herein. The present disclosure also relates to pharmaceutical compositions containing these compounds...
9238150 Optical tissue interface method and apparatus for stimulating cells  
In one example, a system electrically stimulates target cells of a living animal using an elongated structure, a modulation circuit and a light pathway such as provided by an optical fiber...
US20160014876 Distributed Coupling and Multi-Frequency Microwave Accelerators  
A microwave circuit for a linear accelerator has multiple metallic cell sections, a pair of distribution waveguide manifolds, and a sequence of feed arms connecting the manifolds to the cell...
US20160013462 INTERFACIAL ENGINEERING FOR STABLE LITHIUM METAL ANODES  
A battery includes 1) an anode, 2) a cathode, and 3) an electrolyte disposed between the anode and the cathode. The anode includes a current collector and an interfacial layer disposed over the...
US20160008026 APPARATUS AND METHODS INVOLVING ELONGATED-MEDICAL INSTRUMENT FOR SENSING TISSUE INTERACTION FORCES  
Various aspects as described herein are directed to methods and systems that include a tissue-engagement apparatus. The tissue-engagement apparatus includes a distal needle portion having a...
US20160007859 Coherent Frequency-Domain Microwave-Induced ThermoAcoustic Imaging  
A thermoacoustic imaging device is provided having a transmitter configured to provide an electromagnetic transmit signal (e.g. a continuous sinusoidal signal) to an object being imaged. The...
US20160007851 Implantable Pressure Sensors for Telemetric Measurements through Bodily Tissues  
Continuous pressure sensing is important for patients with several different conditions. We provide an implantable sensor, based on microfluidic principles, which in one example has 1 mmHg limit...
9237658 Strongly coupled inorganic-graphene hybrid materials, apparatuses, systems and methods  
Nanocarbon-based materials are provided in connection with various devices and methods of manufacturing. As consistent with one or more embodiments, an apparatus includes a nanocarbon structure...
9236197 Graphene hybrid materials, apparatuses, systems and methods  
Graphene based materials are provided in connection with various devices and methods of manufacturing. As consistent with one or more embodiments, an apparatus includes a graphene sheet and a...
9234790 Apparatus and methods utilizing optical sensors operating in the reflection mode  
Optical apparatus and methods utilizing sensors operating in the reflection mode are provided. The apparatus includes at least one optical bus. The at least one optical bus is configured to be...
9234242 Methods for treating depression using NCAM peptide mimetics  
The present application relates to the treatment and diagnosis of mood disorders, including bipolar disorder, major depression disorder and schizophrenia. The invention provides novel diagnostic...
9234240 Measurement and comparison of immune diversity by high-throughput sequencing  
A precise measurement of the immunological receptor diversity present in a sample is obtained by sequence analysis. Samples of interest are generally complex, comprising more than 102, 103, 104,...
9234229 High throughput system for isolation, growth, and detection of lipid inclusions in bacteria  
A method of high throughput growth and quantitative analysis of microorganisms is provided that includes providing a microtiter plate growth and gas delivery system having well plates disposed for...
9234021 Polypeptides targeting vascular endothelial growth factor receptor-2 and alpha V beta 3 integrin  
Polypeptides comprising variant vascular endothelial growth factor sequences are provided. The polypeptides are useful in cancer imaging, cancer diagnosis, monitoring and treatment as well as...
9233345 Anion transport membrane  
An anion transport membrane is provided enabling efficient anion exchange across the membrane, which could be used in applications like fuel cells, water electrolyzers, or water filtration...
9233166 Supramolecular functionalization of graphitic nanoparticles for drug delivery  
Disclosed are nanoparticles, such as carbon nanotubes or other graphitic sheet materials having extended aromatic surfaces, which are used to deliver active agents such as drugs, labels or dyes...
9233089 Treatment of pulmonary hypertension with leukotriene inhibitors  
Pulmonary arterial hypertension (PAH) can be prevented in persons susceptible to the diseases and PAH patients can be treated by administering an effective dose of a leukotriene inhibitor....
9232947 Closure device and method  
Devices and methods for treatment of prolapsed hemorrhoidal arteries is disclosed. The devices can identify the hemorrhoid and ligate the artery without causing significant pain or distension of...
US20160005277 VISUAL AND TOUCH INTERACTION DISPLAY  
A sensory display for experiencing rigidity and local shape in the display is provided. Rigidity and local shape of cells in an array of cells forming the display is controlled by three...
US20160003798 APPARATUSES AND METHODS FOR DETERMINING ANALYTE CHARGE  
The present disclosure provides a sensor including a pore and an applied electric field that is capable of detecting analytes such as nucleic acids. In accordance with various embodiments, the...
US20160000946 RADIOLABELED ANTI-GLYPICAN-3 IMMUNOCONJUGATES FOR IMMUNO-PET IMAGING OF HEPATOCELLULAR CARCINOMA  
Provided are immunoconjugate probes useful for detecting hepatocellular carcinoma (HCC) lesions. The probes comprise a glypican-3 (GPC3)-specific monoclonal antibody or fragment thereof conjugated...
US20160000412 Integrated System for Ultrasound Imaging and Therapy using Per-Pixel Switches  
Ultrasound imaging and therapy with the same array of capacitive micromachined ultrasonic transducers is provided. The electronics includes a per-pixel switch for each transducer element. The...
9228971 Charge perturbation detection system for DNA and other molecules  
Methods and apparatus for direct detection of chemical reactions are provided. Electric charge perturbations of the local environment during enzyme-catalyzed reactions are sensed by an electrode...
9228931 Imaging and evaluating embryos, oocytes, and stem cells  
Methods, compositions and kits for determining the developmental potential of one or more embryos or pluripotent cells and/or the presence of chromosomal abnormalities in one or more embryos or...
9227326 Remote center of motion mechanism and method of use  
According to one exemplary embodiment, a manipulator device includes a base, first and second linear slides, a drive link, a drive member, a driven member and an end effector. The elements of the...
9227224 Method of forming macro-structured high surface area transparent conductive oxide electrodes  
A method of forming a high surface area transparent conducting electrode is provided that includes depositing a transparent conducting thin film on a conductive substrate, where the transparent...
9227085 Including fiducial markers in radiation therapy planning to facilitate real-time position monitoring during treatment delivery  
An inverse planning method that is capable of controlling the appearance of the implanted fiducial(s) in segmented IMRT fields for cine MV or combined MV/kV image-guided IMRT is provided. The...
9227014 Kalman filter based on-off switch for insulin pump  
Techniques for controlling an insulin pump include determining values for parameters selected from a group including a first prediction time horizon, a predicted glucose threshold (Goff) for...
9226918 Methods and compositions for treating or preventing narcotic withdrawal symptoms  
This invention provides methods and pharmaceutical compositions for preventing or treating physical dependence and/or withdrawal associated with narcotic use, in particular by modulating a 5-HT3...
US20150378054 Optical Fibers Functionalized with Photonic Crystal Resonant Optical Structures  
A photonic crystal (PC) device including one or more resonant optical structures defined by the photonic crystal structure is affixed to the end face of an optical fiber. The PC device is...
US20150377961 SYSTEM AND METHOD FOR TESTING A LOGIC-BASED PROCESSING DEVICE  
A method of operating a test device for a logic-based processing device includes the steps of providing an original set of test instructions, generating one or more Quick Error Detection (QED)...
US20150377905 METHODS FOR DIAGNOSIS OF KAWASAKI DISEASE  
Methods for diagnosis of Kawasaki disease (KD) are disclosed. In particular, the invention relates to the use of biomarkers for aiding diagnosis, prognosis, and treatment of KD, and to a panel of...
US20150377837 Ultrasonic sensor for object and movement detection  
We provide arrays of capacitive micromachined ultrasonic transducer (CMUT) elements having large fractional bandwidth and configured such that each array element operates both to transmit and to...
US20150376798 High aspect ratio dense pattern-programmable nanostructures utilizing metal assisted chemical etching  
A method of ultra-high aspect ratio high resolution vertical directionality controlled metal-assisted chemical etching, V-MACE, is provided that includes forming a pattern on a substrate surface,...
US20150376583 COMPOSITIONS AND METHODS TO TREAT LATENT VIRAL INFECTIONS  
Viral infection is a persistent cause of human disease. Guided nuclease systems target the genomes of viral infections, rendering the viruses incapacitated.
US20150374269 Methods and Apparatus for Rapid Monitoring of Hemostatic State  
Improved monitoring of one or more blood coagulation factors is provided. Factor-specific molecular probes having a dye-quencher arrangement are employed. In preferred embodiments, a compact...
US20150372455 Crossed Nanobeam Structure for a Low-Threshold Germanium Laser  
A crossed nanobeam structure for strain engineering in semiconductor devices is provided. For example, such a structure can be used for a low-threshold germanium laser. While the photonic crystal...
US20150370963 Phased Whole Genome Genetic Risk In A Family Quartet  
In an embodiment of the present invention, three novel human reference genome sequences were developed based on the most common population-specific DNA sequence (“major allele”). Methods were...
US20150370959 Phased Whole Genome Genetic Risk In A Family Quartet  
An embodiment of the present invention is a methodology for prioritizing variants relevant to inherited Mendelian (“single gene”) disease syndromes according to disease phenotype, gene, and...
US20150368697 ON-SLIDE STAINING BY PRIMER EXTENSION  
A method for analyzing planar sample is provided. In some cases the method comprises: (a) incubating the planar sample with a capture agent that is linked to an oligonucleotide, wherein the...