Patents and Patent Applications from Rutgers The State University of NJ


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8185551 Disk-resident streaming dictionary  
A method, apparatus and computer program product for storing data in a disk storage system is presented. A dictionary data structure is defined and stored on the disk storage system. Key-value...
8183395 Compositions and methods for treating cancer  
Compounds of formulas I-IV: (I), (II), (III) (IV), wherein: R1 and R4-R23 are independently selected from H and 1-3 carbon lower alkyl; and R2 and R3 are independently selected from H, 1-3 carbon...
US20120115962 CYCLODEXTRIN-MODIFIED POLYAMINES FOR DELIVERY OF THERAPEUTIC MOLECULES  
The present invention is directed to drug delivery vehicles comprising one or more cyclodextrin moieties conjugated to a dendritic polyamine for the delivery of small molecule and protein...
8173163 Polymeric drug delivery compositions and methods for treating ophthalmic diseases  
Degradable polymeric compositions containing water-insoluble drugs blended with copolymers of biocompatible diphenol compound monomer units with pendant carboxylic acid groups polymerized with...
US20120108677 IMINIC MONOMERS AND POLYMERS THEREOF  
Disclosed are biocompatible, bioresorbable polymers comprising a plurality of monomeric repeating units containing an imine group, wherein the inclusion of said imine group is effective to lower...
US20120106821 IMAGE-BASED RISK SCORE-A PROGNOSTIC PREDICTOR OF SURVIVAL AND OUTCOME FROM DIGITAL HISTOPATHOLOGY  
The present invention relates to an image-based computer-aided prognosis (CAP) system and method that seeks to replicate the prognostic power of molecular assays in histopathology and pathological...
8164345 Spectral and information theoretic method of test point, partial-scan, and full-scan flip-flop insertion to improve integrated circuit testability  
Design for testability (DFT) algorithms, which use both gradient descent and linear programming (LP) algorithms to insert test points (TPs) and/or scanned flip-flops (SFFs) into large circuits to...
US20120093919 E2F AS A TARGET OF HORMONE REFRACTORY PROSTATE CANCER  
The instant invention provides amino acid sequences competing with E2F for DNA binding. Methods of using said amino acid sequences for treatment of hormone-refractory prostate cancer are also...
US20120093723 NANOCARRIER COMPOSITIONS AND METHODS  
This invention provides multimeric nanocarrier for in vivo delivery of a bioactive agent, comprising at least two peptide monomers reversibly or irreversibly linked with one or more of said...
8147863 Polyarylates for drug delivery and tissue engineering  
Biocompatible polyarylates of diphenol compounds and poly(alkylene oxide) dicarboxylic acids, articles formed therefrom and therapeutic uses are disclosed.
8143474 Compositions and methods for increasing transgene expression in the plastids of higher plants  
Nucleic acid constructs comprising a highly efficient 5′ regulatory region for the expression of heterologous proteins from the plastids of higher plants are provided. Also provided are plant c...
US20120071527 THERAPEUTIC COMPOUNDS  
The invention provides compounds of formula I: wherein A, B, D, E, R1, R2, R3, R4, R5, X, and - - - have any values defined herein, as well as salts thereof. The compounds have activity as...
US20120061660 ZnO NANOSTRUCTURE-BASED LIGHT EMITTING DEVICE  
A Light Emitting Diode (LED) formed on a substrate of a material selected from at least one of a semiconductor, an insulator and a metal; at least one semiconductor film layer of ZnO or GaN...
US20120059026 ANTIMICROBIAL AGENTS  
The invention provides a compound of formula (I): or a salt or prodrug thereof, wherein Y, W, Z, Z1, Z2, Z3, Z4, and R1-R12 have any of the values described in the specification, as well as...
US20120058155 SLOW-DEGRADING POLYMERS FOR UNDELAYED AND SUSTAINED DRUG DELIVERY  
The invention provides polymers and methods for their use. Certain embodiments of the invention provide slow degrading microspheres for undelayed and sustained drug delivery.
PP22541 Cranberry plant named ‘CNJ95-20-20’  
A new cranberry variety distinguished by very early season ripening, with exceptional early and high fruit anthocyanin (TAcy), as compared to the currently cultivated commercial varieties, with...
US20120052508 GENETIC MARKERS AND DIAGNOSTIC METHODS FOR RESISTANCE OF BREAST CANCER TO HORMONAL THERAPIES  
This application provides a method to identify genetic markers associated with increased sensitivity or resistance to hormonal therapies using an outlier analysis. More specifically, this...
US20120051976 MULTIFUNCTIONAL BIOSENSOR BASED ON ZNO NANOSTRUCTURES  
The present invention provides the multifunctional biological and biochemical sensor technology based on the integration of ZnO nanotips with bulk acoustic wave (BAW) devices, particularly, quartz...
US20120049767 HIGH BRIGHTNESS EXCIMER LAMP  
A high brightness excimer light source has an elongated tube containing an excimer-forming gas and electrodes for exciting the gas to form a plasma, and thus create excimers such as a rare gas...
8124051 Complex drug delivery composition and method for treating cancer  
The present invention relates to compositions and methods for producing a complex drug delivery system which specifically targets cancer cells, has an increase in cellular uptake, is cytotoxic, and...
US20120045512 METHODS AND SUBSTRATES FOR DIFFERENTIATION OF NEURAL STEM CELLS  
The present invention is directed to methods and substrates for promoting the differentiation of neural stem cells to neurons.
8121347 System and method for detecting and tracking features in images  
A system and method for tracking features, e.g., facial features, is provided, which allows for the tracking of features which move in a series of images and whose shape changes nonlinearly due to...
US20120042415 TRANSGENIC PLANTS EXPRESSING L3 DELTA PROTEINS ARE RESISTANT TO TRICHOTHECENE FUNGAL TOXINS  
Disclosed are specific mutants of L3 and transgenic plants that produce them. The plants exhibit increased resistance to fungal toxins that target ribosomal L3 protein. Also disclosed are...
8114951 Preparation and uses of polyarylates  
The present invention is directed to polyarylates comprising repeating units having the structure: as well as their preparation and use as cell growth substrates.
8114583 Switch-region: target and method for inhibition of bacterial RNA polymerase  
A target and methods for specific binding and inhibition of RNA polymerase from bacterial species are provided, including methods for identifying agents that bind to a bacterial RNA polymerase, and...
8114367 Systems and methods for carbon capture and sequestration and compositions derived therefrom  
A method of sequestering a greenhouse gas is described, which comprises: (i) providing a solution carrying a first reagent that is capable of reacting with a greenhouse gas; (ii) contacting the...
US20120020931 THERAPEUTIC ENCAPSULATED EMBRYONIC STEM CELLS AND MESENCHYMAL STROMAL CELLS  
This application discloses alginate microencapsulation-mediated differentiation of embryonic stem cells and use of the stem cell differentiation method for the development of effective treatment of...
8093235 Macrocyclic compounds which stabilize G-Quadruplex DNA and RNA  
The invention provides compounds of formula I: wherein A, B, D, E, R1, R2, R3, R4, R5, X, and ----- have any values defined herein, as well as salts thereof. The compounds have activity as...
US20120004716 MICROELECTORODE ARRAY, METHODS FOR PREPARING THE SAME AND USES THEREOF  
A microelectrode array having a substrate with a plurality of grooves and a plurality of electrical contact pads, the grooves each with at least one electrode electrically connected to at least one...
US20120004235 METHODS TO TREAT CANCER  
The invention provides methods and pharmaceutical compositions for treating certain cancers with compounds of formula (I) wherein A, B, W, Y, Z, and R1 have any of the meanings defined in the...
8088405 Therapeutic compositions and methods  
Methods of promoting healing through enhanced regeneration of tissue (e.g. hard tissue or soft tissue) by contacting the tissue or the surrounding tissue with an anti-inflammatory agent. These...
US20110320816 SYSTEMS AND METHOD FOR MALWARE DETECTION  
A system and method for distinguishing human input events from malware-generated events includes one or more central processing units (CPUs), one or more input devices and memory. The memory...
US20110318403 Preparation and Use of Pouteria Lucuma Extract  
A method of preparing Pouteria lucuma extract was developed which comprises extracting oil from the nut. The lucuma nut oil (LNO) was effective to induce cell migration, enhance tissue regeneration...
US20110302678 Cranberry variety named 'CNJ95-20-20'  
A new cranberry variety distinguished by very early season ripening, with exceptional early and high fruit anthocyanin (TAcy), as compared to the currently cultivated commercial varieties, with...
8071685 Method of recycling paints as a component of an immiscible polymer blend  
An immiscible polymer blend including a first polymer component including a paint polymer phase and a second polymer component immiscible with the first polymer component and selected from...
8071642 Dimethyl amino ethyl ether psoralens and methods for their production and use  
Water-soluble dimethyl amino ethyl ether psoralens useful in the treatment of proliferative skin disorders, microbial infections and diseases, disorders of the blood and bone marrow of mammals and...
US20110294917 USE OF RECYCLED PLASTICS FOR STRUCTURAL BUILDING FORMS  
Modular plastic structural composites formed from a mixture of (A) high density polyolefin and one or both of: (B) a thermoplastic-coated fiber material, or (C) polystyrene, poly(methyl...
8067158 Methods and compositions for the diagnosis and treatment of schizophrenia  
Compositions and methods relating to the diagnosis and treatment of neuropsychiatric disorders, such as schizophrenia, schizoaffective disorders, and bipolar disorders are disclosed. Also provided...
US20110286926 DEGRADABLE HYDROGEL COMPOSITIONS AND METHODS  
This invention concerns an in situ biodegradable hydrogel drug delivery system in which the components are assembled in a manner that provides a mechanism for the timed cleavage of a particular...
US20110282067 ZEOLITIC IMIDAZOLATE FRAMEWORKS FOR KINETIC SEPARATION OF PROPANE AND PROPENE  
Zeolitic Imidazolate Frameworks (ZIFs) characterized by organic ligands consisting of imidazole ligands that are either essentially all 2-chloroimidazole ligands or essentially all 2-bromoimidazole...
US20110275782 BIORESORBABLE POLYMERS SYNTHESIZED FROM MONOMER ANALOGS OF NATURAL METABOLITES  
New bioresorbable polymers are synthesized from monomer analogs of natural metabolites In particular, polymers are polymerized from analogs of amino acids that contribute advantageous synthesis,...
US20110275505 Sinterable semi-coke powder with high bulk density  
In a continuous method for production of a semicoke powder with high bulk density and flowability, a sinterable carbon powder (semicoke) is dispersed in water with addition of at least one binder...
US20110269848 N-SUBSTITUTED MONOMERS AND POLYMERS  
Biocompatible, bioresorbable polymers comprising a plurality of monomeric repeating units containing an amide group, wherein said amide groups are N-substituted and the N-substituent and degree of...
US20110268803 LUNG TARGETING DUAL DRUG DELIVERY SYSTEM  
The American Cancer Society estimated that in 2009, 1,479,350 new cancer cases would be diagnosed in the United States of which 219,440 would be lung and bronchus related. The standard treatments...
US20110265410 USE OF RECYCLED PLASTICS FOR STRUCTURAL BUILDING FORMS  
Modular plastic structural composites having a web section disposed along a horizontal axis and at least one flange section disposed along a horizontal axis parallel thereto and integrally molded...
PP22219 Interspecific hybrid dogwood tree designated ‘KF 111-1’  
An advanced generation interspecific hybrid of Cornus kousa and C. florida that is distinguished by its exceptionally high vigor, attractive foliage, very floriferous display of white floral...
8049417 High brightness excimer lamp  
A high brightness excimer light source has an elongated tube containing an excimer-forming gas and electrodes for exciting the gas to form a plasma, and thus create excimers such as a rare gas...
8048486 Flame-retardant coating  
A flame-retardant coating composition, which includes a cross-linked thermosetting polymer and a metal hydroxide. A precursor composition for use in preparing the flame retardant-coating is also...
US20110254449 FLUORESCENT EXCIMER LAMPS  
Excimers are formed in a high pressure gas by applying a potential between a first electrode (14, 214) and a counter electrode (25, 226) so as to impose an electric field within the gas, or by...
8039149 Bismuth oxyfluoride based nanocomposites as electrode materials  
The present invention relates to bismuth oxyfluoride nanocomposites used as positive electrodes in primary and rechargeable electromechanical energy storage systems.