Patents and Patent Applications from Rutgers The State University of NJ


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9789194 Graft copolymer polyelectrolyte complexes for drug delivery  
Graft copolymer polyelectrolyte complexes are disclosed for the efficient delivery of anionic, cationic or polyelectrolyte therapeutic agents into biological cells, and for maintaining the...
9784914 Waveguide superlattices for high density photonics integrations  
An apparatus and method for transmitting a plurality of light signals is disclosed. The apparatus includes a splitter configured to split an incoming light signal into a plurality of light...
9782495 Proteins expressed by Mycobacterium tuberculosis and not by BCG and their use as diagnostic reagents and vaccines  
The present invention is directed to reagents useful for generating immune responses to Mycobacterium tuberculosis and for diagnosing infection and disease in a subject that has been exposed to M....
9782432 Polymers and methods thereof for wound healing  
Certain embodiments of the invention provide a copolymer having a backbone, wherein the backbone comprises a) one or more units that comprise a group that will yield a biologically active agent...
US20170280729 BACTERIA WITH 1-AMINOCYCLOPROPANE-1-CARBOXYLIC ACID (ACC) DEAMINASE FOR PROMOTING TURFGRASS GROWTH  
Compositions and methods for enhancing turfgrass quality and resistance to adverse abiotic conditions are disclosed.
9775907 Cochleates made with soy phosphatidylserine  
Unpurified or low pure soy phosphatidylserine is used to make cochleates. The cochleates contain about 40-74% soy phosphatidylserine, a multivalent cation and a biological active. A preferred...
US20170273293 Dispensers and Methods of Use Thereof for Dispensing Solid Mosquito Larvicides and Other Materials of Interest  
Dispenser devices suitable for use on unmanned aerial vehicles are described having utility for dispensing solid larvicides to difficult to reach insect habitats.
9770470 Closed system separation of adherent bone marrow stem cells for regenerative medicine applications  
A method for isolating and processing bone marrow derived stem cells, including the steps of: (a) collecting a biological sample containing adherent bone marrow stem cells in a receptacle with...
9770465 Inherently radiopaque polymeric products for embolotherapy  
Preferred embodiments relate to compositions of inherently radiopaque, biocompatible, bioresorbable polymeric particles and methods of using them for embolizing a body lumen.
9765196 Inorganic ionomers made from minerals  
Inorganic polymers are produced from silicate (—Si—O—) and/or phosphonate (—P—O—) bonds, commonly found in rocks and glass, to create new polymeric materials for rubbers, fibers, and plastics....
9763968 Hydrogel formulation for dermal and ocular delivery  
Formulations of cross-linkable polymers, capable of forming non-toxic and biocompatible hydrogels in situ, containing at least one of doxycycline or minocycline. Methods of using the hydrogels for...
9761493 Thin epitaxial silicon carbide wafer fabrication  
Techniques for fabricating thin epitaxial SiC device wafers are described. A bulk SiC wafer is used to provide a seed layer of a thin layer of SiC for epitaxially growing SiC. The seed layer is...
9758794 HCV E2 construct compositions and methods  
Methods of producing and using Hepatitis C virus (HCV) eE2 polypeptides are described.
9757499 Biomaterial and methods of use thereof for the prevention of post-operative adhesions  
Biofunctional films and methods of use thereof for the prevention of post-operative adhesions are disclosed.
9752192 Compositions and methods for diagnosing autism  
Mutations located within the gene encoding the homeobox transcription factor, ENGRAILED 2 (EN2), have now been identified as molecular markers associated with susceptibility for autism and related...
US20170247747 Polymerase Chain Reaction Primers and Probes for Mycobacterium Tuberculosis  
The present invention relates to novel primers and sloppy molecular beacon and molecular beacon probes for amplifying segments from different genes in Mycobacterium tuberculosis for identifying...
US20170246351 Biocompatible Textile Sleeves to Support and Guide Muscle Regeneration and Methods of Use Thereof  
A biocompatible sleeve designed to encase an assembly of small 3D muscles that have been cultured in vitro. The sleeve is formed from polymer fibers in such a way that pushing the two ends of the...
US20170246128 NOVEL D3 DOPAMINE RECEPTOR AGONISTS TO TREAT DYSKINESIA IN PARKINSON'S DISEASE  
The present invention provides a method of inhibiting, suppressing or preventing levodopa-induced dyskinesia in a patient suffering from Parkinson's Disease, comprising the step of administering...
US20170245505 HERBAL ESSENTIAL OIL FOR BIOMATERIAL PRESERVATION  
Compositions and methods for inhibiting the decomposition of agricultural products are provided. A composition comprises a breathable sachet of cyclodextrin-encapsulated plant essential oils, such...
9746350 Manual manipulation apparatus  
A manual manipulation apparatus including a frame assembly, at least one handle associated with frame assembly, a mounting structure configured for mounting of a computer device relative to the...
9744528 Metallorganocatalysis for asymmetric transformations  
A ligand having the structure or its enantiomer; (I) wherein: each one of Ra, Rb, Rc and Rd is selected from alkyl, cycloalkyl, and aryl; the bridge group is selected from CH2NH; *CH(CH3)NH(C*,R);...
US20170243486 VEHICULAR INFORMATION SYSTEMS AND METHODS  
Disclosed is a method and system that receives sensor information from each of a plurality of sensors. Each sensor in the plurality is associated with a vehicle. The sensor information includes...
PP28311 Cornus kousa tree designated ‘Rutpink’  
A new Cornus kousa cultivar that is clearly distinguished by its floriferous display of showy, dark-pink floral bracts, attractive dark-green foliage, high level of winter hardiness, and tolerance...
9732378 Fluorophore chelated lanthanide luminescent probes with improved quantum efficiency  
The invention relates to novel luminescent compositions of matter containing a fluorophore, synthetic methods for making the compositions, macromolecular conjugates of the compositions, and the...
9730946 Use of vanadium compounds to accelerate bone healing  
This invention provides a method of promoting bone healing by locally administering a vanadium-based insulin mimetic agent to a patient in need thereof. The invention also provides a new use of...
US20170226201 Methods of diagnosing and treating hyperproliferative disorders  
The invention relates to compositions and methods for diagnosing and treating hyperproliferative disorders using ligands which specifically recognize the hypusine and/or folate binding region of...
US20170224856 FLEXIBLE PLASMA APPLICATORS BASED ON FIBROUS LAYERS  
Disclosed herein are flexible plasma applicators based on fibrous layers that are capable of rapidly sanitizing a surface via either direct or indirect contact with said surface.
9725427 Prodrugs of riluzole and their method of use  
Pharmaceutical compositions of the invention include substituted riluzole prodrugs useful for the treatment of cancers including melanoma, breast cancer, brain cancer, and prostate cancer through...
9724384 Methods to treat inflammation of the lung  
The present invention provides pharmaceutical compositions comprising leukotoxin for the treatment of lung inflammation.
US20170218141 Graphene-Reinforced Polymer Matrix Composites  
A graphene-reinforced polymer matrix composite comprising an essentially uniform distribution in a thermoplastic polymer of about 10% to about 50% of total composite weight of particles selected...
US20170217878 ANTIBACTERIAL AGENTS  
The invention provides an antibacterial compound of formula (I) or a salt thereof, as well as an antibacterial compound of formula (II) or a salt thereof, wherein R1, R2, X, Y and n have any of...
9721338 Method and apparatus for segmentation and registration of longitudinal images  
The described invention provides systems and methods for detecting and segmenting a lesion from longitudinal, time series, or multi-parametric imaging by utilizing spectral embedding-based active...
US20170211085 GIGANTUS1 (GTS1) GENE AND METHODS OF USE THEREOF FOR IMPROVING BIOMASS ACCUMULATION AND HIGHER YIELD IN PLANTS  
Compositions and methods are provided for enhancing growth, seed germination, and biomass production in transgenic plants expressing reduced levels of GIGANTUS1 (gts1).
US20170211072 METHODS AND COMPOSITIONS FOR INHIBITING GROWTH AND EPITHELIAL TO MESENCHYMAL TRANSITION (EMT) IN CANCER CELLS  
Provided herein are methods and compositions for inhibiting epithelial to mesenchymal transition of a cell.
US20170210771 IRIDIUM PINCER COMPLEX FOR ALKANE DEHYDROGENATION PROCESS  
Disclosed herein are processes for dehydrogenation of an alkane to an alkene using an iridium pincer complex and iridium pincer complexes. In the dehydrogenation reactions, hydrogen that is...
US20170210628 Scalable Multiple-Inverse Diffusion Flame Burner for Synthesis and Processing of Carbon-Based and Other Nanostructured Materials and Films and Fuels  
Apparatus and methods of use thereof for the production of carbon-based and other nanostructures, as well as fuels and reformed products, are provided.
US20170204083 THERAPEUTIC HYDROXYPYRIDINONES, HYDROXYPYRIMIDINONES AND HYDROXYPYRIDAZINONES  
The invention provides compounds of formula I: and salts and prodrugs thereof wherein R4, X1 and X2 have any of the meanings defined in the specification, as well as pharmaceutical compositions...
9709554 In vitro model of macrosteatotic (fatty) liver  
The present invention relates to a system and methods for identifying a compound for de-fatting and functional recovery of macrosteatotic hepatocytes.
9708671 Detection of drug resistant Mycobacterium tuberculosis  
This invention relates to nucleic acids, reagents and methods for detecting Rifampicin-resistant Mycobacterium tuberculosis in a sample from a subject. In one aspect, the invention provides...
9708611 RNA targeting in alpha-synucleinopathies  
Therapies and assays to screen for small molecules that can have therapeutic use in the control of neurodegenerative diseases such as Parkinson's and other alpha-synucleinopathies.
US20170199219 HIGH SPEED ADAPTIVE-MULTI-LOOP MODE IMAGING ATOMIC FORCE MICROSCOPY  
A method for imaging a sample using a high speed dynamic mode atomic force microscope may include scanning a tip of a cantilever probe over a surface of the sample, regulating a vibration...
US20170198261 SINGLE CELL-DERIVED ORGANOIDS  
The present invention relates to organoids derived from a single cell, such as a prostate cancer cell, and methods and compositions relating to the production and use thereof, including cell...
9701638 Therapeutic hydroxyquinolones  
The invention provides compounds of formula (I) and salts thereof wherein R4-R8 have any of the meanings defined in the specification, as well as pharmaceutical compositions comprising the...
9700638 Near infrared label and methods of use thereof  
The present invention provides compounds useful as novel near-infrared labels, compositions containing these compounds, and methods of using the near-infrared labels to identify targets in vitro,...
US20170190421 UNMANNED AIR AND UNDERWATER VEHICLE  
An unmanned vehicle including a body and a frame structure extending from the body and supporting a plurality of propeller assemblies, each propeller assembly including at least one propeller and...
9695135 Therapeutic catechols  
The invention provides compounds of formula I: and salts thereof wherein R1-R4 have any of the meanings defined in the specification, as well as pharmaceutical compositions comprising the...
9682094 Targeting matriptase expressing tumor cells with chemotherapeutic agents conjugated to matriptase antibodies  
The present invention relates to matriptase antibodies and immunoconjugates of matriptase antibodies with cytotoxic agents and the use thereof for killing or inhibiting the growth of...
US20170166611 ANTIBACTERIAL AGENTS: SALINAMIDE DERIVATIVES  
The invention provides compounds of formula (I): and salts thereof, wherein X and Y have any of the values defined herein. The compounds inhibit bacterial RNA polymerase, inhibit bacterial growth,...
9676682 Catalyst complex and use thereof in alkane oligomerization  
Provided is a Group 9 novel metal catalyst complex further comprising a ketone-containing cocatalyst. The metal catalyst complex is useful in generating olefins from alkanes with great efficiency....
9675565 D3 dopamine receptor agonists to treat dyskinesia in parkinson's disease  
The present invention provides a method of inhibiting, suppressing or preventing levodopa-induced dyskinesia in a patient suffering from Parkinson's Disease, comprising the step of administering...