Patents and Patent Applications from Purdue Research Foundation


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US20170354758 Glycosaminoglycan-Based Materials as an Engineered Biocompatible Cellular Matrix  
Disclosed herein is a cross-linked polymeric system comprising thiolated hyaluronic acid (HA), thiolated chondroitin sulfate (CS), and functionalized polyethylene glycol (PEG), wherein said...
US20170354118 NESTING MATERIAL BALING AND DISPENSING SYSTEM FOR MOUSE ENVIRONMENTAL ENRICHMENT  
A standardized nesting material for use in laboratory environments for rodents includes a latrining substrate, and at least one bale unit formed to include a fibrous scaffolding material, and an...
9841327 Method of producing conductive patterns of nanoparticles and devices made thereof  
A method of processing a liquid material. The method includes mixing a liquid material with a solvent, wherein the solvent has a constituent capable of coating the particles of the material. The...
9839724 System and stent for repairing endovascular defects and methods of use  
Disclosed are endovascular stents in which a portion of the stents have a bioactive coating for promoting repair of damaged vessels, systems comprising the stents, and methods of using the stents...
9839250 Dynamic load-absorbing materials and articles  
A double-shell helmet is disclosed. The double-shell helmet includes an outer shell, an impact absorbing material layer affixed to the outer shell on a first side of the impact absorbing material...
US20170349903 siRNA COMPOSITIONS THAT SPECIFICALLY DOWNREGULATE EXPRESSION OF A VARIANT OF THE PNPLA3 GENE AND METHODS OF USE THEREOF FOR TREATING A CHRONIC LIVER DISEASE OR ALCOHOLIC LIVER DISEASE (ALD)  
The invention provides siRNA compositions that specifically downregulates expression of a variant of the PNPLA3 gene and methods of use thereof for treating a chronic liver disease or alcoholic...
US20170349547 CONDUCTING REACTIONS IN LEIDENFROST-LEVITATED DROPLETS  
The invention generally relates to conducting reactions in Leidenfrost-levitated droplets.
9835634 Coupled heterogeneous devices for pH sensing  
Provided herein are methods and devices for measuring pH and for amplifying a pH signal to obtain ultrasensitive detection of changes in pH. This is achieved by providing a sensor and a...
9834448 Preparation of amine-boranes, including ammonia borane  
Disclosed herein is a method for preparing amine-boranes.
US20170343987 MICROCONTROLLER ENERGY MANAGEMENT SYSTEM  
A microcontroller system which employs an intermediate approach in hybrid FRAM-SRAM that involves memory mapping of program sections to retain the reliability benefits provided by FRAM while...
US20170343526 METHODS OF ANALYZING CRUDE OIL  
The invention generally relates to methods of analyzing crude oil. In certain embodiments, methods of the invention involve obtaining a crude oil sample, and subjecting the crude oil sample to...
US20170343485 RETRIEVAL OF P-BAND SOIL REFLECTIVITY FROM SIGNALS OF OPPORTUNITY  
A system and method for determining moisture content of soil, comprising providing bistatic radar configuration to measure soil reflectivity in UHF and S-band, cross-correlating between Sky-viewed...
US20170343481 METHODS AND SYSTEMS FOR CRACK DETECTION  
Systems and methods suitable for capable of autonomous crack detection in surfaces by analyzing video of the surface. The systems and methods include the capability to produce a video of the...
US20170342461 TYROSINE KINASE BIOSENSORS AND METHODS OF USE  
Disclosed are compositions and methods for measuring tyrosine kinase activity.
9829482 Motility-contrast imaging for oocyte and embryo viability assessment  
A method and system is provided for evaluating viability of oocytes and embryos comprising imaging an oocyte or embryo using motility contrast imaging; generating temporal contrast and spatial...
US20170336431 SYSTEM AND METHOD FOR MEASURING EXHAUST FLOW VELOCITY OF SUPERSONIC NOZZLES  
A system for measuring supersonic nozzle exhaust flow, comprising a seeding module, an optics module configured to direct an optical signal from the supersonic nozzle, and a streak camera. The...
US20170335477 SYSTEMS AND METHODS FOR PRODUCING METAL CLUSTERS; FUNCTIONALIZED SURFACES; AND DROPLETS INCLUDING SOLVATED METAL IONS  
The invention generally relates to systems and methods for producing metal clusters; functionalized surfaces; and droplets including solvated metal ions. In certain aspects, the invention provides...
9823358 Low-noise surface level MOS capacitor for improved sensor quality factor  
A low-power wireless ionizing radiation measurement system is provided that is intended to be used in a wearable dosimeter for occupational radiation monitoring.
9821055 Vaccine adjuvants  
The present invention provides a new adjuvant for administering vaccines.
US20170331109 METHODS OF MAKING ELECTRODES, ELECTRODES MADE THEREFROM, AND ELECTROCHEMICAL ENERGY STORAGE CELLS UTILIZING THE ELECTRODES  
Method of making interconnected layered porous carbon sheets with porosity within the carbon sheets and in-between the carbon sheets for use as an electrode. Method of making a metal-nanoparticle...
US20170330070 SPIN ORBIT TORQUE BASED ELECTRONIC NEURON  
An electronic neuron device that includes a thresholding unit which utilizes current-induced spin-orbit torque (SOT). A two-step switching scheme is implemented with the device. In the first step,...
US20170326689 METHODS OF FORMING A SUBSTRATE HAVING AN OPEN PORE THEREIN AND PRODUCTS FORMED THEREBY  
Methods and products formed thereby that include depositing a light-absorbing particle on a substrate and irradiating the particle with a pulsed laser beam to cause an increase in local...
9817745 Binary program instrumentation and debugging  
Disclosed is a system and method for setting breakpoints (BPs) that cannot be detected by code being debugged, e.g., to trap transparently at any instruction. The disclosed system and method...
9816852 System for weighing individual micro- and nano-sized particles  
A device for weighing micro- and nano-sized particles. The device includes a base portion, an oscillator coupled to the base portion and configured to vibrate the base portion, a first...
US20170321607 SYSTEM AND METHOD FOR STABILIZING TRANSCRITICAL AIR-TO-FUEL HEAT EXCHANGE  
A gas turbine engine includes devices, systems, and methods for design and operation of stabilizing heat exchangers for gas turbine engines in consideration of near supercritical fuel flow conditions.
US20170320992 POLY(ALKYLENE CARBONATE)-BASED AMPHIPHILIC BLOCK COPOLYMERS AND METHODS OF USE THEREOF  
This invention provides poly(alkylene carbonate)-based amphiphilic block copolymers, compositions comprising the same, e.g., micelles, and methods of use thereof. This invention further provides...
US20170320164 LASER-ASSISTED MICROMACHINING SYSTEMS AND METHODS  
Laser-assisted micromachining methods and systems capable of providing flexible beam positioning and low incident angles. Such laser-assisted micromachining systems preferably include a laser beam...
US20170319657 METHOD OF TREATING A BLADDER CANCER USING A CHIMERIC EGF-TARGETED BACTERIAL TOXIN  
Provided is a method of treating a bladder cancer in an animal or human comprising: administering to an animal or human patient a therapeutic composition comprising a first fusion protein capable...
9813048 Electronic comparison systems  
An electronic comparison system includes input stages that successively provide bits of code words. One-shots connected to respective stages successively provide a first bit value until receiving...
9808527 Methods and compositions for treating HIV infections  
Described herein are compounds and compositions that are useful in the treatment of HIV, AIDS, and AIDS-related diseases. In addition, compounds are described herein that are capable of inhibiting...
US20170313738 RAMAN TAG  
The present invention provides novel Raman tags for exploring membrane interactions in cells. The tags comprise a phenyl diyne probe where in the dyine is capped with the phenyl group. Methods for...
US20170313685 BROAD-SPECTRUM NON-COVALENT CORONAVIRUS PROTEASE INHIBITORS  
This invention pertains to materials and methods for the treatment of patients with coronavirus infection and the control of zoonotic disease outbreaks using broad-spectrum non-covalent...
US20170312795 SYSTEMS WITH ANTI-FOULING CONTROL AND METHODS FOR CONTROLLING FOULING WITHIN A CHANNEL OF A PLUG FLOW CRYSTALLIZER  
The invention generally relates to systems with anti-fouling control and methods for controlling fouling within a channel of a plug flow crystallizer. In certain aspects, the invention provides a...
US20170311559 MOISTURE MANAGEMENT & PERENNIAL CROP SUSTAINABILITY DECISION SYSTEM  
Disclosed herein are a system and method that integrate vineyard sensor data into an environment that enables analysis, historical trend analytics, spatio-temporal analytics, and weather model...
9806306 Impact resistant battery enclosure systems  
Battery enclosure arrangements for a vehicular battery system. The arrangements, capable of impact resistance include plurality of battery cells and a plurality of kinetic energy absorbing...
9804273 Combined n-type and p-type MOS-based radiation sensors for environmental compensations  
An apparatus is disclosed comprising a metal oxide semiconductor capacitor (MOSCAP) comprising one or more gate layers disposed over a contiguous radiation-sensitive insulating layer, wherein the...
9804159 Immunoreactive antigens of Mycoplasma haemofelis and diagnostic immunoassay  
Compositions for use in diagnostic screens for Mycoplasma haemofelis are provided. In one embodiment an immunogenic peptide selected from SEQ ID NO: 1 to SEQ ID NO: 60, or a fragment thereof, is...
9802833 Synthesis of metal oxide-based thermoelectric materials for high temperature applications  
Nanowire synthesis and one dimensional nanowire synthesis of titanates and cobaltates. Exemplary titanates and cobaltates that are fabricated and discussed include, without limitation, strontium...
9801861 Antimicrobial substituted thiazoles and methods of use  
Disclosed are compositions having activity against MRSA and/or VRSA, and methods of using the compositions to treat microbial infections.
9801568 Gait pattern analysis for predicting falls  
A method for acquiring gait parameters of an individual is disclosed. The method includes capturing calibration images from foot marker placed on feet or shoes of an individual while an individual...
US20170309462 Mass spectrometry analysis of microorganisms in samples  
The invention generally relates to systems and methods for mass spectrometry analysis of microorganisms in samples.
US20170307533 Metal-Antibody Tagging and Plasma-based Detection  
An apparatus and method for characterizing a target, e.g., microbial samples or biological toxins, includes labeling the target with a biomolecular recognition construct and measuring an...
9797872 Ion generation using modified wetted porous materials  
The invention generally relates to ion generation using modified wetted porous materials. In certain aspects, the invention generally relates to systems and methods for ion generation using a...
9796753 N-substituted indenoisoquinolines and syntheses thereof  
N-Substituted indenoisoquinoline compounds, and pharmaceutical formulations of N-substituted indenoisoquinoline compounds are described. Also described are processes for preparing N-substituted...
US20170296505 LONG-CHAIN CARBOXYCHROMANOLS AND ANALOGS FOR USE AS ANTI-INFLAMMATORY AGENTS  
Long-chain carboxychromanol compounds useful for treating conditions associated with the need to inhibit cyclooxygenase-1, cyclooxygenase-2, and/or 5-lipoxygenase, and pharmaceutical formulations...
9789339 System design and method for verifying 3D dosimetric imaging of charged particles in media  
A method of verifying therapeutic proton beam delivery accuracy by ultrasound tomographic imaging to map three dimensional (3D) proton dose through the detection of ionizing radiation induced...
9789208 Synthesis and composition of amino acid linking groups conjugated to compounds used for the targeted imaging of tumors  
The present disclosure relates to compounds that are useful as near-infrared fluorescence probes, wherein the compounds include i) a pteroyl ligand that binds to a target receptor protein, ii) a...
9788953 System and method of attaching soft tissue to an implant  
One embodiment of the present invention is directed to compositions and methods for enhancing attachment of soft tissues to a metal prosthetic device. In one embodiment a construct is provided...
US20170290900 CHIMERIC ANTIGEN RECEPTOR-EXPRESSING T CELLS AS ANTI-CANCER THERAPEUTICS  
Cytotoxic lymphocytes expressing chimeric antigen receptors (CAR) that target and bind small conjugate molecules (SCM) are disclosed, as well as methods of using the cells and the SCMs in the...
9787969 Figure ground organization of 3-D scenes  
Systems and methods for processing a pair of 2-D images are described. In one example, a stereoscopic set of images is converted into a collection of regions that represent individual 3-D objects...