Patents and Patent Applications from Purdue Research Foundation


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US20170296505 LONG-CHAIN CARBOXYCHROMANOLS AND ANALOGS FOR USE AS ANTI-INFLAMMATORY AGENTS  
Long-chain carboxychromanol compounds useful for treating conditions associated with the need to inhibit cyclooxygenase-1, cyclooxygenase-2, and/or 5-lipoxygenase, and pharmaceutical formulations...
9789339 System design and method for verifying 3D dosimetric imaging of charged particles in media  
A method of verifying therapeutic proton beam delivery accuracy by ultrasound tomographic imaging to map three dimensional (3D) proton dose through the detection of ionizing radiation induced...
9789208 Synthesis and composition of amino acid linking groups conjugated to compounds used for the targeted imaging of tumors  
The present disclosure relates to compounds that are useful as near-infrared fluorescence probes, wherein the compounds include i) a pteroyl ligand that binds to a target receptor protein, ii) a...
9788953 System and method of attaching soft tissue to an implant  
One embodiment of the present invention is directed to compositions and methods for enhancing attachment of soft tissues to a metal prosthetic device. In one embodiment a construct is provided...
US20170290900 CHIMERIC ANTIGEN RECEPTOR-EXPRESSING T CELLS AS ANTI-CANCER THERAPEUTICS  
Cytotoxic lymphocytes expressing chimeric antigen receptors (CAR) that target and bind small conjugate molecules (SCM) are disclosed, as well as methods of using the cells and the SCMs in the...
9787969 Figure ground organization of 3-D scenes  
Systems and methods for processing a pair of 2-D images are described. In one example, a stereoscopic set of images is converted into a collection of regions that represent individual 3-D objects...
9786478 Zero voltage mass spectrometry probes and systems  
The invention generally relates to zero volt mass spectrometry probes and systems. In certain embodiments, the invention provides a system including a mass spectrometry probe including a porous...
9784960 High frame-rate multichannel beam-scanning microscopy  
A beam-scanning optical design is described for achieving up to kHz frame-rate optical imaging on multiple simultaneous data acquisition channels. In one embodiment, two fast-scan resonant mirrors...
9784888 Titanium nitride based metamaterial  
A titanium nitride-based metamaterial, and method for producing the same, is disclosed, consisting of ultrathin, smooth, and alternating layers of a plasmonic titanium nitride (TiN) material and a...
9783474 Catalytic biomass conversion methods, catalysts, and methods of making the same  
Described herein are processes for one-step delignification and hydrodeoxygenation of lignin fraction a biomass feedstock. The lignin feedstock is derived from by-products of paper production and...
9782499 Block copolymer (BCP) encapsulated nanoparticles and methods of use thereof  
This invention provides block copolymer (BCP) encapsulated nanoparticles. The BCP-encapsulated nanoparticles are used in methods for targeting a tumor, in methods of imaging a tumor and in methods...
9782497 Synthesis and composition of amino acid linking groups conjugated to compounds used for the targeted imaging of tumors  
The present disclosure relates to compounds that are useful as near-infrared fluorescence probes, wherein the compounds include i) a pteroyl ligand that binds to a target receptor protein, ii) a...
US20170287690 ION FOCUSING  
The invention generally relates to apparatuses for focusing ions at or above ambient pressure and methods of use thereof. In certain embodiments, the invention provides an apparatus for focusing...
US20170286815 GENERATING AN OBJECT MAP FROM A PLURALITY OF BINARY IMAGES  
In an example, a method is described that includes dividing an input image into a plurality of strips, where each strip is smaller than a whole of the input image. A plurality of binary images is...
US20170285262 Passive Optical Diode on Semiconductor Substrate  
A method of fabricating an optical device includes forming on a semiconductor substrate a first optical cavity, a second optical cavity, a first light guide and a second light guide. The first...
US20170284935 SYSTEM AND METHOD FOR SENSING AND TRAPPING NANOPARTICLES WITH PLASMONIC NANOPORES  
An apparatus for trapping and sensing nanoparticles using plasmonic nanopores, comprising a conductive transparent layer, a conductive film layer mounted to a substrate, the film layer comprising...
US20170283852 NOVEL UBIQUITINATION SYSTEM AND THE USES THEREOF  
An unprecedented mechanism of ubiquitination that is independent of E1 and E2 enzymes, instead relying on activation of ubiquitin by ADP-ribosylation, and which is mediated by members of the SidE...
US20170283458 COLLAGEN-BINDING SYNTHETIC PEPTIDOGLYCANS FOR WOUND HEALING  
Methods and compositions for promoting wound healing in a patient by administering a collagen-binding synthetic peptidoglycan to the patient are described. Additionally, methods and compositions...
US20170281800 SYNTHESIS AND COMPOSITION OF AMINO ACID LINKING GROUPS CONJUGATED TO COMPOUNDS USED FOR THE TARGETED IMAGING OF TUMORS  
The present disclosure relates to compounds that are useful as near-infrared fluorescence probes, wherein the compounds include i) a pteroyl ligand that binds to a target receptor protein, ii) a...
9780715 Hybrid surface magnet machine  
A hybrid electrical machine containing surface mounted magnets which includes a magnetically permeable cylindrically shaped stator assembly having at least one stator winding formed about a...
9780206 Methods of reducing the electrical and thermal resistance of SiC substrates and devices made thereby  
A power semiconductor device includes a silicon carbide substrate and at least a first layer or region formed above the substrate. The silicon carbide substrate has a pattern of pits formed...
9780190 InP-based transistor fabrication  
Methods of forming structures that include InP-based materials, such as a transistor operating as an inversion-type, enhancement-mode device. A dielectric layer may be deposited by ALD over a...
9778400 System and method for manipulation of particles  
A system and method suitable for selection, manipulation, and analysis of individual particles within a fluid medium. The system and method involve manipulating the particles by contacting the...
9778194 In-situ combined sensing of uniaxial nanomechanical and micromechanical stress with simultaneous measurement of surface temperature profiles by raman shift in nanoscale and microscale structures  
Embodiments of the present disclosure include separating a measured Raman shift signal into mechanical and thermal components when a uniaxial compressive load is applied in situ. In some...
9777341 Locally-regulated pressurized pretreatment of lignocellulosic biomass  
Described are methods for pretreating lignocellulosic biomass that comprise passing a hot aqueous biomass slurry through a heat exchange passage from an inlet to an outlet and locally regulating...
US20170280106 PUBIC SAFETY CAMERA IDENTIFICATION AND MONITORING SYSTEM AND METHOD  
A system for determining a travel path, including a network of at least one camera, a communication hub coupled to the network of at least one camera, at least one electronic communication device,...
US20170280105 PUBIC SAFETY CAMERA MONITORING SYSTEM AND METHOD  
A system for determining a travel path, including a network of at least one camera, a communication hub coupled to the network of at least one camera, at least one electronic communication device,...
US20170279384 MOTOR CONTROL SYSTEM AND METHOD  
A motor control interface system, comprising an interface communication module configured to connect to a wired control port of a rotating electronically controlled motor, such as in an HVAC...
US20170275713 COMPOSITIONS AND METHODS FOR TREATING LEATHER  
The present disclosure provides a composition for treating leather and similar materials. The composition comprises from about 40% (w/w) to about 60% (w/w) of an oil obtained from natural sources;...
US20170275345 COLLAGEN-BINDING SYNTHETIC PEPTIDOGLYCANS, PREPARATION, AND METHODS OF USE  
This invention relates to collagen-binding synthetic peptidoglycans and engineered collagen matrices comprising a collagen matrix and a collagen-binding synthetic peptidoglycan where the...
US20170274120 COLLAGEN-BASED THERAPEUTIC DELIVERY SYSTEMS  
A collagen-based therapeutic delivery device includes an insoluble synthetic collagen-fibril matrix comprising a polymerization product of soluble oligomeric collagen or a polymerization product...
US20170273731 NOVEL TECHNIQUE FOR THERAPEUTIC CONTACT LENS SYSTEMS  
The invention relates to electronic contact lens systems, methods for fabrication thereof, and uses thereof for treatment of ophthalmic diseases and conditions, for example, meibomian gland...
US20170273605 ENCLOSED DESORPTION ELECTROSPRAY IONIZATION PROBES AND METHOD OF USE THEREOF  
The invention generally relates to enclosed desorption electrospray ionization probes, systems, and methods. In certain embodiments, the invention provides a source of DESI-active spray, in which...
US20170273256 BOTANICAL AIR FILTRATION SYSTEM AND METHOD  
A system and process for filtering air by removing pollutants from the air with living plants. The system includes an enclosure, a wall within the enclosure on which living plants are supported...
9774479 Communicating data using backscatter modulation  
A system and method for full duplex wireless communication is disclosed. The system utilizes backscatter modulation of a first signal received by a guest device from a basestation to transmit a...
9773843 Electronic memory using memristors and crossbars with three or more in-series activated memristors  
A memory system comprising a plurality of layers of spaced-apart row electrodes, each having a dorsal and a ventral side, a plurality of layers of spaced-apart column electrodes, each having a...
9771345 Coferons and methods of making and using them  
The present invention is directed to a monomer useful in preparing therapeutic compounds. The monomer includes one or more pharmacophores which potentially binds to a target molecule with a...
US20170269300 SINGLE PHOTON SOURCE  
The invention related to single photon emission systems based on nano-diamonds. Single-photon sources have a broad range of applications in quantum communication, quantum computing and quantum...
US20170267667 ALKENYLDIARYLMETHANES AS NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS FOR ANTI-HIV-1 CHEMOTHERAPY  
The invention disclosed herein pertains to compounds of alkenyldiarylmethanes (ADAMs) as non-nucleoside reverse transcriptase inhibitors (NNRTIs) for the treatment of patients with acquired-immune...
US20170266719 HOT-CHAMBER DIE CASTING SYSTEMS AND METHODS  
Hot-chamber die casting systems for casting aluminum, copper, titanium, and their alloys, as well as other high temperature and/or reactive metals. The hot-chamber die casting system comprises an...
US20170266303 METHODS OF TREATING CANCER BY TARGETING TUMOR-ASSOCIATED MACROPHAGES  
Methods for treating cancers using one or more compounds comprising a folate receptor binding ligand attached to a drug via a linker are described. Methods for treating cancers using one or more...
9767258 System and method of extending the linear dynamic range of event counting  
A method and apparatus for photon, ion or particle counting described that provides seven orders of magnitude of linear dynamic range (LDR) for a single detector. By explicitly considering the...
US20170262726 TEX LINE DETECTION  
A system and method for text line detection are described Examples include detection of symbols in an image received from an image-capturing device. In examples, for each of at least some of the...
US20170258923 PSMA BINDING LIGAND-LINKER CONJUGATES AND METHODS FOR USING  
Described herein are prostate specific membrane antigen (PSMA) binding conjugates that are useful for delivering therapeutic, diagnostic and imaging agents. Also described herein are...
D796858 Chair  
9761426 Synchronization of ion generation with cycling of a discontinuous atmospheric interface  
The invention generally relates to methods and devices for synchronization of ion generation with cycling of a discontinuous atmospheric interface. In certain embodiments, the invention provides a...
9760422 Interactive, constraint-network prognostics and diagnostics to control errors and conflicts (IPDN)  
Methods for interactively preventing and detecting conflicts and errors (CEs) through prognostics and diagnostics. Centralized and Decentralized Conflict and Error Prevention and Detection (CEPD)...
9758542 Protein chromatography matrices with hydrophilic copolymer coatings  
A coating of a random copolymer of acrylamide and a second monomer, e.g. glycidoxylmethacrylate, for a silica surface is described. The coating is applied to chromatographic support structures...
US20170256406 PROCESSES FOR SHAPING NANOMATERIALS  
Processes for shaping one- and two-dimensional nanomaterials, and thereby inducing local strains therein preferably to control one or more of their material properties. The processes include...
US20170253962 PLASMA-ENHANCED CHEMICAL VAPOR DEPOSITION METHODS FOR GRAPHENE DEPOSITION  
A graphene deposition process. The process includes the steps of placing a substrate into a deposition chamber and heating the chamber, generating radio frequency plasma at a location proximate to...