Patents and Patent Applications from Purdue Research Foundation


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8183043 Sol-gel materials for cellular modulation  
A modified sol-gel material and method of making the same is provided herein. More particularly, sol-gels disclosed herein have been modified to have one or more bioactive peptides covalently bound...
US20120122268 SELENIZATION OF PRECURSOR LAYER CONTAINING CULNS2 NANOPARTICLES  
A method of fabrication of thin films for photovoltaic or electronic applications is provided. The method includes fabricating a nanocrystal precursor layer and selenizing the nanocrystal precursor...
US20120122112 ANTIBODIES AS A CANCER DIAGNOSTIC  
Method and kits are provided for the detection and diagnosis of metastatic disease. More particularly, the methods and kits employ compounds that can detect EphA2, a specific epithelial cell...
US20120119079 ION GENERATION USING WETTED POROUS MATERIAL  
The invention generally relates to systems and methods for mass spectrometry analysis of samples. In certain embodiments, the invention provides a mass spectrometry probe including at least one...
US20120118036 SYSTEM AND METHOD FOR REDUCING THE AMPLITUDE OF THERMALLY INDUCED VIBRATIONS IN MICROSCALE AND NANOSCALE SYSTEMS  
The present invention generally relates to a system and method for improving the precision and applicability of microscale and nanoscale electromechanical systems. The system includes a device...
US20120115708 METHOD OF PRODUCING PARTICULATE-REINFORCED COMPOSITES AND COMPOSITES PRODUCED THEREBY  
A process for producing particle-reinforced composite materials through utilization of an in situ reaction to produce a uniform dispersion of a fine particulate reinforcement phase. The process...
US20120115312 THIN FILMS FOR PHOTOVOLTAIC CELLS  
In one aspect, a method for forming CIGSSe-based thin films includes depositing at least two layers of particles on a substrate. At least one layer includes a CIGSSe particle having a chemical...
US20120115222 COMPOSITION AND METHOD FOR MAINTENANCE, DIFFERENTIATION, AND PROLIFERATION OF STEM CELLS  
Compositions and methods for the proliferation, differentiation, and maintenance of stem cells are described. Preferred are the use of hematopoietic stem cells in combination with a collagen matrix.
8175115 Method and system for iterative reconstruction  
A method for reconstructing an image of an object, the image comprising a plurality of image elements, is disclosed. The method includes accessing image data associated with the plurality of image...
US20120107955 METABOLITE BIOMARKERS FOR THE DETECTION OF ESOPHAGEAL CANCER USING MS  
Results of studies of nucleosides in biofluid specimens from patients with esophageal adenocarcinoma and related disorders have identified five biomarkers of the conditions: 1-methyladenosine,...
US20120107830 REAGENTS FOR BIOMOLECULAR LABELING, DETECTION AND QUANTIFICATION EMPLOYING RAMAN SPECTROSCOPY  
The present disclosure provides isotopically substituted compounds of the formula (II): wherein T, U, V, W, X, Y, Z, R0, R3, R4, R5 and R6 are as defined in the detailed description. The method for...
8168164 Targeted conjugates and radiation  
The invention relates to a method for enhancing an endogenous immune response-mediated elimination of a population of cancer cells in a host. The method comprises the steps of administering to the...
8166796 System and method for improving the precision of nanoscale force and displacement measurements  
A self-calibrating apparatus comprises a primary device and a test structure fabricated on an integrated circuit chip. The primary device and the test structure have at least one unknown property...
US20120100106 COLLAGEN-BINDING SYNTHETIC PEPTIDOGLYCANS FOR WOUND HEALING  
Methods and compositions for promoting wound healing in a patient by administering a collagen-binding synthetic peptidoglycan to the patient are described. Additionally, methods and compositions...
8163545 Vaccine against pandemic strains of influenza viruses  
The present disclosure provides compositions and methods for eliciting an immune response against avian or pandemic influenza. The compositions include adenovirus vectors comprising avian influenza...
8153827 Reagents for biomolecular labeling, detection and quantification employing Raman spectroscopy  
The present disclosure provides isotopically substituted compounds of the formula (I): wherein T, U, V, W, X, Y, Z, R0, R3, R4, R5 and R6 are as defined in the detailed description. The method for...
US20120083688 HEAD INJURY DIAGNOSTICS  
Systems and methods for detecting the effects of concussion are disclosed. In various embodiments, fMRI or other live analysis technique captures data regarding the subject's brain activity while...
US20120079936 POSITIVE DISPLACEMENT MACHINE PISTON WITH WAVY SURFACE FORM  
A piston and cylinder assembly suitable for use in positive displacement machines (10) and capable of minimizing power losses resulting from friction and fluid leakage over a range of operating...
8135186 Method and system for image reconstruction  
Disclosed is an imaging system including a source generating an x-ray beam, a detector array receiving the x-ray beam and generating projection data, a translatable table configured for disposal of...
8133789 Short-channel silicon carbide power mosfet  
A silicon carbide power MOSFET having a drain region of a first conductivity type, a base region of a second conductivity type above the drain region, and a source region of the first conductivity...
US20120059161 COMPOUNDS AND METHODS FOR TREATING AIDS AND HIV INFECTIONS  
Macrocycle containing carbamate compounds that inhibit HIV proteolytic enzymes and processes for preparing them are described. Compositions and methods for treating a patient infected with HIV are...
US20120058524 METHODS FOR INCREASING THE YIELD OF FERMENTABLE SUGARS FROM PLANT STOVER  
Methods for increasing yield of fermentable sugars from plant stover are provided. The methods include using plants homozygous for two brown midrib mutations, bm1 and bm3. The methods also include...
8129459 Soy methyl ester polystyrene blends for use in concrete  
A non-aqueous blend composition for treating a porous material comprising triacylglycerides obtained, from vegetable oils and containing a fatty acid component and a polystyrene dissolved in the...
8123564 Apparatus and system for electronic device interrogation and data extraction  
An apparatus for connecting a computing device to different types of mobile devices that includes an enclosure that encloses a USB hub, mobile device cables connectable to different mobile devices,...
US20120046644 TOUCH-ACTUATED MICROPUMP FOR TRANSDERMAL DRUG DELIVERY AND METHOD OF USE  
A micropump device. The micropump device includes a first layer forming a first chamber configured to store a working material, a second chamber defined by a deflectable membrane in fluid...
8118582 Method and apparatus for producing biobased carriers from byproducts of biomass processing  
An apparatus for producing biobased carriers for dispersal of biological and chemical molecules includes a premixer having a cavity for receiving a coproduct of a wet biomass process and a binder...
US20120041018 OCTAHYDROBENZOISOQUINOLINE MODULATORS OF DOPAMINE RECEPTORS AND USES THEREFOR  
Octahydrobenzoisoquinoline modulators of dopamine receptors are described herein. Methods for using octahydrobenzoisoquinoline modulators of dopamine receptors in the treatment of dopamine...
8115766 System and method for rendering flow and volumes  
A system and method for rendering flows and volumes includes the steps of generating a preintegrated table, the preintegrated table having a plurality of entries, each of the plurality of entries...
8114622 Methods for generation of reporter phages and immobilization of active bacteriophages on a polymer surface  
Novel reporter bacteriophages are provided. Provided are compositions and methods that allow bacteriophages that are used for specific detection or killing of E. coli 0157:H7 to be propagated in...
US20120035429 ANIMAL SYMPTOM VISUAL ANALYTICS  
A system and method for visually displaying and analyzing public health data for geospatial and/or time variations, including the collection of symptom data coupled with geographic and time data,...
US20120031193 IDENTIFICATION OF LOADS ACTING ON AN OBJECT  
Structural health monitoring systems can be limited to a minimum number of sensors due to cost, complexity, and weight restrictions. Some embodiments described herein pertain to a load and damage...
8107397 Protocol for secure and energy-efficient reprogramming of wireless multi-hop sensor networks  
A protocol for optimizing the energy for code upload to sensors in a wireless sensor network and speeding up the dissemination if multiple sources of code are available. Energy optimization is...
8105608 Method of treatment using ligand-immunogen conjugates  
A method and pharmaceutical composition are provided for enhancing the endogenous immune response-mediated elimination of a population of pathogenic cells in a host animal wherein the pathogenic...
US20120022245 FOLATE TARGETING OF NUCLEOTIDES  
The present invention relates to compounds, compositions, kits, and methods of use in targeting nucleotides, such as siRNA's, to cancer cells or to immune system cells involved in inflammation....
US20120021918 DNA Sequencing and Amplification Systems Using Nanoscale Field Effect Sensor Arrays  
In one aspect, described herein are field effect chemical sensor devices useful for chemical and/or biochemical sensing. Also provided herein are methods for single molecule detection. In another...
US20120021690 ANTENNA AIMING SYSTEM AND METHOD FOR BROADBAND WIRELESS ACCESS  
A system and method are provided for automatically aiming an antenna to communicate with a remote broadband wireless communication device.
US20120013230 COLLAPSIBLE FURNITURE JOINTING SYSTEM  
Methods for constructing and apparatus for furniture. In some embodiments, the furniture includes a plurality of subassemblies, with each component within the subassembly being interlocked with...
8097638 Pyridines for treating injured mammalian nerve tissue  
The invention provides novel pyridines, pharmaceutical compositions comprising such pyridines, and the use of such compositions in treating injured mammalian nerve tissue, including but not limited...
US20120006022 ORGANIC RANKINE CYCLE WITH FLOODED EXPANSION AND INTERNAL REGENERATION  
A heat engine system configured to extract thermal energy from a heat source, convert a first portion of the thermal energy to work using an expansion device, and reject a second portion of the...
8095079 Decentralized control of feedback for multi-user diversity  
A communication apparatus includes a mobile terminal to measure a downlink channel state of a downlink between a base station and the mobile terminal, and to determine whether to transmit feedback...
8094378 Planar lens  
A design method, apparatus, and fabrication method for structures for controlling the flow of electromagnetic energy at a sub-wavelength scale is disclosed. Transformational optics principles are...
8093715 Enhancement of thermal interface conductivities with carbon nanotube arrays  
A method of forming a well-anchored carbon nanotube (CNT) array, as well as thermal interfaces that make use of CNT arrays to provide very high thermal contact conductance. A thermal interface is...
US20120003151 METHOD FOR EARLY IMAGING OF ATHEROSCLEROSIS  
The invention relates to methods of detecting active atherosclerotic plaques associated with blood vessel walls wherein the plaques comprise activated macrophages having accessible binding sites...
8088912 pRNA chimera  
A polyvalent multimeric complex formed from a plurality of circularly permuted chimeric pRNA molecules, each carrying a stabilized biologically active moiety.
US20110317017 PREDICTIVE DUTY CYCLE ADAPTATION SCHEME FOR EVENT-DRIVEN WIRELESS SENSOR NETWORKS  
Embodiments of a method for controlling access to a shared communications medium by a plurality of nodes are disclosed. The method may comprise predicting, for each node of the plurality of nodes,...
US20110314915 DAMAGE DETECTION USING LASER VIBROMETRY  
Methods and apparatus for exciting a structure and determining its structural integrity. In particular, methods of nonlinear analysis are used to compare first and second response datasets, each...
8084055 Collagen preparation and method of isolation  
Collagen compositions, methods for preparing those collagen compositions, and graft compositions formed from those collagen compositions are provided. In particular, methods of isolating collagen...
8084048 Vascularization enhanced graft constructs  
A tissue graft construct for use in repairing diseased or damaged tissues is provided. The tissue graft construct comprises a matrix composition selected from the group consisting of liver basement...
US20110310255 CALIBRATION OF LARGE CAMERA NETWORKS  
The present disclosure relates to a sensor network including a plurality of nodes, each node having a directional sensor, a communication module, and a processor configured to receive local...
8080483 Double gyroid structure nanoporous films and nanowire networks  
A method of forming a nanoporous film is disclosed. The method comprises forming a coating solution including clusters, surfactant molecules, a solvent, and one of an acid catalyst and a base...