Patents and Patent Applications from Princeton University


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10079189 P-type transparent conducting nickel oxide alloys  
Disclosed herein is the formation of p-type transparent conducting oxides (TCO) having a structure of MgxNi1-xO or ZnxNi1-xO. These structures disrupt the two-dimensional confinement of individual...
10077460 Method for awakening silent gene clusters in bacteria and discovery of cryptic metabolites  
The majority of clinically used antibiotics and anticancer agents are derived from bacterial small molecules. These molecules are produced by dedicated biosynthetic gene clusters, sets of genes...
10077273 SHMT inhibitors  
The disclosure provides compounds of Formulae (I)-(IX). The disclosed compounds are capable of inhibiting a mammalian SHMT. Compounds of the disclosure have numerous uses, such as for treatment of...
US20180257054 GRADIENT INDUCED PARTICLE MOTION IN SUSPENSIONS  
Methods of inducing or controlling particle motion in suspensions and colloids are described. In one aspect, a method of inducing particle motion in a suspension comprises contacting the...
10072048 Astexin peptides  
Provided are astexin-1, astexin-2 and astexin-3 lasso peptides, which are based on sequences identified in Asticaccaulis excentricus, and methods of making and using same. Astexin-1 is highly...
US20180252559 ELASTIC FILAMENT VELOCITY SENSOR  
Disclosed is an apparatus for measuring velocity of a fluid stream via deflection of a wire filament. Also disclosed is a process for measuring velocity of a fluid stream, requiring deflecting two...
US20180251497 DISORDERED PROTEIN-BASED SEEDS FOR MOLECULAR CLUSTERING  
A system and method for reversibly controlling clustering of proteins around an engineered multivalent nucleus is disclosed. The system and method utilize clustering, which may be controlled by...
10068716 Graphene-ionic liquid composites  
Method of making a graphene-ionic liquid composite. The composite can be used to make electrodes for energy storage devices, such as batteries and supercapacitors.
US20180244528 Hyperuniform and Nearly Hyperuniform Random Network Materials  
This invention is in the field of physical chemistry and relates to novel hyperuniform and nearly hyperuniform random network materials and methods of making said materials. Methods are described...
US20180243229 COMPOSITE FLASH-PRECIPITATED NANOPARTICLES  
The invention described herein relates to sterically stabilized colloidal constructs comprising preformed colloidal particles encapsulated within a polymeric shell. The constructs, which are...
10063191 Frequency and back-off reconfigurability in mm-wave power amplifiers  
A power amplifier system for amplifying an input having a carrier frequency having an amplitude. The system includes a plurality of n amplifiers coupled to an asymmetrical combiner formed of a...
10059596 Hyperuniform and nearly hyperuniform random network materials  
This invention is in the field of physical chemistry and relates to novel hyperuniform and nearly hyperuniform random network materials and methods of making said materials. Methods are described...
10057986 Thermal overload device containing a polymer composition containing thermally exfoliated graphite oxide and method of making the same  
A thermal overload device containing a polymer composite, which contains at least one polymer and a modified graphite oxide material, containing thermally exfoliated graphite oxide having a...
10055739 System and method for pricing and exchanging content  
A system and method for pricing and exchanging content is provided, which includes a data plane formed by a peer-to-peer content sharing network or a central server allowing for client-server...
US20180230472 METHODS OF IDENTIFYING AND TREATING POOR-PROGNOSIS CANCERS  
The present invention relates generally to methods for identifying cancer patients with a poor prognosis, and to therapeutic modalities for improving prognosis by combating metastasis and...
US20180228736 NANO-ENCAPSULATION USING GRAS MATERIALS AND APPLICATIONS THEREOF  
In one aspect, methods of preparing composite nanoparticle compositions are described herein. For example, in some embodiments, a method comprises providing a zein solution stream, an organic...
10048201 Fluid channels for computational imaging in optofluidic microscopes  
A microscope is disclosed, the microscope having a light source defining an optical axis along a Z direction and a detector disposed in X-Y direction, orthogonal to the optical axis, the detector...
US20180221509 PARTICULATE CONSTRUCTS FOR RELEASE OF ACTIVE AGENTS  
Particulate constructs stabilized by amphiphilic copolymers and comprising at least one active coupled to a hydrophobic moiety provide sustained release of the active in both in vitro and in vivo...
US20180201634 DEHYDROGENATIVE SILYLATION, HYDROSILYLATION AND CROSSLINKING USING PYRIDINEDIIMINE COBALT CARBOXYLATE CATALYSTS  
A process for producing a silylated product comprises reacting a mixture comprising (a) an unsaturated compound containing at least one unsaturated functional group, (b) a silyl hydride containing...
US20180199436 PRINTED ELECTRONICS  
Printed electronic device comprising a substrate onto at least one surface of which has been applied a layer of an electrically conductive ink comprising functionalized graphene sheets and at...
US20180196393 GLOBAL TIME SERVER FOR HIGH ACCURACY MUSICAL TEMPO AND EVENT SYNCHRONIZATION  
Systems, methods and apparatus directed to a global metronome configured at each of one or more locations to receive a high accuracy timing signal and responsively update a local clock thereto, to...
US20180193280 Process and Apparatuses For Preparing Nanoparticle Compositions with Amphiphilic Copolymers and Their Use  
This invention discloses a process for making nanoparticles of amphiphilic copolymers by flash precipitation. Nanoparticles may be of amphiphilic copolymer alone or may contain an additive target...
10020438 Magnetic topological nanowires  
A magnetic topological nanowire structure comprises a superconductor and a quasi-1D magnetic nanowire. The quasi-1D magnetic nanowire is coupled to or embedded in the superconductor to produce a...
10017632 Functionalized graphene sheets having high carbon to oxygen ratios  
Functionalized graphene sheets having a carbon to oxygen molar ratio of at least about 23:1 and method of preparing the same.
10016517 Bioactive amphiphilic polymer stabilized nanoparticles with enhanced stability and activity  
The present invention relates to nanoparticle compositions and treatment of cardiovascular disease using nanoparticles to target Class A and B scavenger receptors. This invention further relates...
US20180188418 Narrow-Band Frequency Filters and Splitters, Photonic Sensors, and Cavities Having Pre-Selected Cavity Modes  
Waveguides and electromagnetic cavities fabricated in hyperuniform disordered materials with complete photonic bandgaps are provided. Devices comprising electromagnetic cavities fabricated in...
US20180185374 INHIBITORS OF MTOR KINASE AS ANTI-VIRAL AGENTS  
The present invention provides methods and compositions for treating or preventing viral infections using modulators of host cell enzymes relating to mTOR. The invention also provides methods and...
US20180184901 STRESS DETECTION AND ALLEVIATION SYSTEM AND METHOD  
According to various embodiments, a stress detection and alleviation (SoDA) system for a user is disclosed. The system includes a SoDA device configured with one or more processors that receive...
10013108 System and method for 3D position and gesture sensing of human hand  
A three dimensional touch sensing system having a touch surface configured to detect a touch input located above the touch surface is disclosed. The system includes a plurality of capacitive touch...
US20180179248 DECARBOXYLATIVE CONJUGATE ADDITIONS AND APPLICATIONS THEREOF  
Synthetic methods are described herein operable to efficiently produce a wide variety of molecular species through conjugate additions via decarboxylative mechanisms. For example, methods of...
10009135 System and method for photonic processing  
According to some embodiments, a network architecture is disclosed. The network architecture includes a plurality of processing network nodes. The network architecture further includes at least...
US20180175313 SINGLE-JUNCTION ORGANIC PHOTOVOLTAIC DEVICES HAVING HIGH OPEN-CIRCUIT VOLTAGES AND APPLICATIONS THEREOF  
In one aspect, single-junction organic photovoltaic devices are provided exhibiting high Voc values while employing N single-junction architecture. A single-junction photovoltaic device described...
US20180159037 3D PRINTED ACTIVE ELECTRONIC MATERIALS AND DEVICES  
Disclosed is a process whereby diverse classes of materials can be 3D printed and fully integrated into device components with active properties. An exemplary embodiment shows the seamless...
US20180155532 MULTIFUNCTIONAL GRAPHENE-SILICONE ELASTOMER NANOCOMPOSITE, METHOD OF MAKING THE SAME, AND USES THEREOF  
A nanocomposite composition having a silicone elastomer matrix having therein a filler loading of greater than 0.05 wt %, based on total nanocomposite weight, wherein the filler is functional...
9985251 Process for fabricating a porous film in a scattering layer  
The present invention is directed towards a thin-film device. In one embodiment, the thin film device comprises a scattering layer comprising a substrate, the substrate comprising a plurality of...
9984450 Method and apparatus for enhancement of ultrasound images by selective differencing  
A computer implemented method and apparatus for processing images comprises obtaining two or more images acquired by ultrasound. One or more operating parameters of the ultrasound probe...
9968587 Heterocycle analogs of CAI-1 as agonists of quorum sensing in vibrio  
A structurally distinct and potent series of synthetic small molecule activators of Vibrio cholerae quorum sensing have been chemically synthesized. The small molecule activators reduce virulence...
US20180126189 Precise Proton Positioning Method for Proton Therapy Treatment, and Proton Therapy Treatment Method  
A system/apparatus and a positioning method for the determination of the delivery of protons within a mammalian body or inanimate medium, as well as a treatment method which comprises the delivery...
US20180125066 SURFACES COMPRISING ATTACHED QUORUM SENSING MODULATORS  
The invention relates to compositions comprising QS modulating molecules attached to a surface via a linker. This QS modulator attached surface can then be used to modulate QS, biofilm production,...
9966216 Photo-electron source assembly with scaled nanostructures and nanoscale metallic photonic resonant cavity, and method of making same  
A new ultra-thin high-efficiency photoelectron source utilizing a metallic photonic resonant cavity having a photonic resonant cavity with a top metallic layer with a plurality of openings, each...
9965802 Method for bidding battery storage into hour-ahead energy markets  
A method for generating bids for a look-ahead, e.g. hour-ahead, energy market is disclosed. The method includes providing a processor configured to generate a lookup table approximating a value...
US20180117010 SHMT Inhibitors  
The present invention relates to a method for the treatment of cancer or an autoimmune disorder, comprising the administration of a serine hydroxymethyltransferase (SHMT) inhibitor, and in...
9959883 Method and system for producing low-noise acoustical impulse responses at high sampling rate  
The method and system for measuring low-noise acoustical impulse responses at high sampling rates of the present invention utilizes two exponential sine sweeps (ESSs) to measure the impulse...
9956179 Process and apparatuses for preparing nanoparticle compositions with amphiphilic copolymers and their use  
This invention discloses a process for making nanoparticles of amphiphilic copolymers by flash precipitation. Nanoparticles may be of amphiphilic copolymer alone or may contain an additive target...
US20180109946 SECURE OPTICAL COMMUNICATION CHANNEL FOR IMPLANTABLE MEDICAL DEVICES  
An implantable medical device (IMD) configured to communicate with an external device (ED). The ED supports two way RF communications and has a light source. The IMD includes a processor coupled...
9943490 Composite flash-precipitated nanoparticles  
The invention described herein relates to sterically stabilized colloidal constructs comprising preformed colloidal particles encapsulated within a polymeric shell. The constructs, which are...
US20180092861 NOVEL DROPLET-EMBEDDED MICROFIBERS, AND METHODS AND DEVICES FOR PREPARING AND USING SAME  
The invention includes microfluidic methods and devices that allow for the continuous production of microfibers with embedded droplets aligned along the length of the fiber at specific positions....
9932587 Methods of identifying and treating poor prognosis cancers  
The present invention relates generally to methods for identifying cancer patients with a poor prognosis, and to therapeutic modalities for improving prognosis by combating metastasis and...
US20180083320 Alkaline Battery Electrolyte Useful for a Rechargeable Alkaline Electrochemical Cell  
The invention provides an electrolyte composition which is adapted for use in a rechargeable alkaline electrochemical cell, and especially preferably adapted for use in a rechargeable manganese...
US20180078526 HETEROCYCLE ANALOGS OF CAI-1 AS AGONISTS OF QUORUM SENSING IN VIBRIO  
A structurally distinct and potent series of synthetic small molecule activators of Vibrio cholerae quorum sensing have been chemically synthesized. The small molecule activators reduce virulence...