Patents and Patent Applications from Penn State University


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7641850 Method and apparatus for strengthening of powder metal gears by ausforming  
A technique for net shaping gear teeth of a high performance power transmission gear from a powder metal workpiece includes heating a powder metal workpiece in the form of a near net shaped gear...
US20090318462 PROTEIN KINASE C ZETA INHIBITION TO TREAT VASCULAR PERMEABILITY  
Methods of treating or preventing a disease or disorder in a subject are provided by the present invention which include administering a composition including a therapeutically effective amount of...
US20090317882 ELECTROMETHANOGENIC REACTOR AND PROCESSES FOR METHANE PRODUCTION  
Increasing competition for fossil fuels, and the need to avoid release carbon dioxide from combustion of these fuels requires development of new and sustainable approaches for energy production and...
US20090311213 METHODS AND COMPOSITIONS FOR TREATMENT OF RETINOID-RESPONSIVE CONDITIONS  
Methods and composition for treating a retinoid-responsive condition in a subject are provided according to embodiments of the present invention which include administering a therapeutically...
US20090308685 DIPOLE FLOW DRIVEN RESONATORS FOR FAN NOISE MITIGATION  
A fan system includes a rotor supported for rotation about a fan axis. The rotor has a central hub and a plurality of blades each extending outwardly from the hub to a tip. The rotor blades define...
7628977 Particles for inhalation having sustained release properties  
The invention generally relates to a method for pulmonary delivery of therapeutic, prophylactic and diagnostic agents to a patient wherein the agent is released in a sustained fashion, and to...
US20090298085 Detection of Extracellular Tumor-Associated Nucleic Acid in Blood Plasma or Serum Using Nucleic Acid Amplification Assays  
This invention relates to detection of specific extracellular nucleic acid in plasma or serum fractions of human or animal blood associated with neoplastic or proliferative disease. Specifically,...
US20090296223 FLAT TRANSFORMATIONAL ELECTROMAGNETIC LENSES  
Examples of the present invention include methods and apparatus for modification of electromagnetic waves, including lenses with generally parallel flat surfaces. Lenses may comprise metamaterials,...
US20090293345 Blends of Synthetic Distillate and Biodiesel for Low Nitrogen Oxide Emissions from Diesel Engines  
This invention shows how to make and use a biodiesel-based fuel in diesel engines without incurring the NO x penalty. Embodiments primarily relate to an optimum range of bulk modulus of...
7622851 High temperature piezoelectric material  
Piezoelectric devices with excellent high temperature operation capabilities are described, including piezoelectric sensors and actuators that use a rare earth calcium oxyborate or langanite as the...
US20090286839 PHYTONUTRIENT COMPOSITIONS FROM MUSHROOMS OR FILAMENTOUS FUNGI AND METHODS OF USE  
This invention is directed to treating disease states or conditions associated with the treatment and prevention of neurodegeneration and neurodegenerative disease states, and treatment of...
7620819 System and method for classifying regions of keystroke density with a neural network  
We develop a system consisting of a neural architecture resulting in classifying regions corresponding to users' keystroke patterns. We extend the adaptation properties to classification phase...
7618383 Neonatal chest brace and method of using same to prevent collapse of a chest wall  
A chest brace and method of using same that prevents the chest wall from buckling inwards during patient breathing by providing a distending force on the patient's thorax. The chest brace also...
US20090280166 FERRITIN AS A THERAPEUTIC TARGET IN ABNORMAL CELLS  
Compositions for treatment of iron related diseases comprise an inhibitor of ferritin. An inhibitor of ferritin is active to reduce the level of H ferritin protein in a cell and/or to reduce the...
7615912 Acoustic transducer  
An electroacoustic transducer having a tail mass, a head mass and at least two parallelepiped shaped piezoelectric material elements disposed between and attached to the tail mass and the head mass...
US20090269441 Methods and compositions for improving the nutritional content of mushrooms and fungi  
An improved filamentous fungi is disclosed that has an enhanced nutritional profile by utilizing pulsed ultraviolet irradiation. According to the invention, the vitamin D component of mushrooms and...
7604787 Process for sequestering carbon dioxide and sulfur dioxide  
A process for sequestering carbon dioxide, which includes reacting a silicate based material with an acid to form a suspension, and combining the suspension with carbon dioxide to create active...
US20090255194 TRANSPARENT SUSTAINABLE WALL SYSTEM  
A sustainable energy saving wall utilizing recyclable materials is disclosed for use in construction where the wall provides natural light to the interior of the structure while also providing...
7598058 Nucleic acids encoding IL13 mutants  
This invention provides nucleic acid molecules encoding mutant human interleukin 13 molecules showing varying specificity for the restricted (IL4 independent) IL13 receptor. The mutant hIL13...
US20090242405 BOTTOM-UP ASSEMBLY OF STRUCTURES ON A SUBSTRATE  
Examples of the present invention include methods of assembling structures, such as nanostructures, at predetermined locations on a substrate. A voltage between spaced-apart electrodes supported by...
US20090241209 HIGH LYCOPENE CONTENT TOMATO PLANTS AND MARKERS FOR USE IN BREEDING FOR SAME  
Solanum pimpinellifolium plants which are exceptionally high in fruit lycopene content (˜300-390 μg lycopene/g fresh fruit) are disclosed herein, which may be used in plant breeding to make the...
7589218 Chiral spiro compounds and their use in asymmetric catalytic reactions  
The present invention provides a chiral ligand, represented by a formula or its enantiomer: X and X′ can be independently O, NH, NR, NCOR or S; each of Z 1 -Z 7 and Z 1 ′-Z 7 ′ can be...
7585865 Protein kinase C zeta inhibition to treat vascular permeability  
Methods of treating or preventing a disease or disorder in a subject are provided by the present invention which include administering a composition including a therapeutically effective amount of...
7585334 Manufacturing method for molecular rulers  
A multi-layer resist process is used to define a sacrificial host structure used to produce a molecular ruler useful for defining structures via a lift-off type process. By using this process, the...
7580488 Broadband modulation/demodulation apparatus and a method thereof  
A modulator/demodulator apparatus and method for applications, such as communications, active sensing and navigation is disclosed. The modulator time-delays and time-scales (compresses or dilates)...
7575918 Tissue-specific and pathogen-specific ribozymes  
The present invention relates to the discovery, identification and characterization of toxic agents which are lethal to pathogens and methods for targeting such toxic agents to a pathogen or...
US20090204637 REAL-TIME COMPUTERIZED ANNOTATION OF PICTURES  
A computerized annotation method achieves real-time operation and better optimization properties while preserving the architectural advantages of the generative modeling approach. A novel...
US20090201221 METHOD AND APPARATUS FOR REDUCED COUPLING AND INTERFERENCE BETWEEN ANTENNAS  
Examples of the present invention include antennas and scattering elements having a metamaterial cloak configured so as to reduce effects on the operating parameters of a nearby antenna. For...
7572380 Method for oxyanion removal from ground water  
A carbonaceous material that has been loaded with at least one ionic organic species or hydroxide species and at least one metal or alkaline earth metal. The ionic organic species or hydroxide...
US20090198071 TETRAPHOSPHORUS LIGANDS FOR CATALYTIC HYDROFORMYLATION AND RELATED REACTIONS  
Tetraphosphorous ligands are combined with transition metal salts to form catalysts for use in hydroformylation, isomerization-hydroformylation, hydrocarboxylation, hydrocyan-ation,...
US20090198031 ONE-POT PROCESS AND REAGENTS FOR PREPARING LONG CHAIN BRANCHED POLYMERS  
A one-pot polymerization process of preparing long chain branching polymers is provided. Also described is a “T” reagent that serves as a link between main and side chains of an inventive long...
US20090197848 Synthetic mimics of mammalian cell surface receptors: method and compositions  
The present invention relates to new synthetic receptors. More particularly, the present invention relates to the use of the synthetic receptors for delivering a protein, peptide, drug, prodrug,...
7569350 Methods for selecting cancer vaccine therapies using extracellular DNA  
This invention relates to detection of specific extracellular nucleic acid in plasma or serum fractions of human or animal blood associated with neoplastic or proliferative disease. Specifically,...
7569349 Methods for selecting monoclonal antibody therapies using extracellular DNA  
This invention relates to detection of specific extracellular nucleic acid in plasma or serum fractions of human or animal blood associated with neoplastic or proliferative disease. Specifically,...
7563915 Green biodiesel  
Methods for improved manufacture of green biodiesel focus on the selection and use of one or more solid metallic oxide base catalyst(s) selected from the group consisting of calcium oxide (CaO),...
US20090159455 BIO-ELECTROCHEMICALLY ASSISTED MICROBIAL REACTOR THAT GENERATES HYDROGEN GAS AND METHODS OF GENERATING HYDROGEN GAS  
Systems and processes for producing hydrogen using bacteria are described. One detailed process for producing hydrogen uses a system for producing hydrogen as described herein, the system including...
US20090156895 PRECISE ENDOSCOPIC PLANNING AND VISUALIZATION  
Endoscopic poses are used to indicate the exact location and direction in which a physician must orient the endoscope to sample a region of interest (ROI) in an airway tree or other luminal...
US20090145233 CARBON NANOTUBE-QUARTZ RESONATOR WITH FEMTOGRAM RESOLUTION  
Methods for sensing and building sensors provide for adding nanotubes to a sensor to improve characteristics such as the Q-factor associated with the sensor. Mass loading and damping...
US20090143241 ANTIBACTERIAL AND PLASMID ELIMINATION AGENTS  
Inhibitors of the tmRNA pathway have antibacterial activity with broad species specificity, including B. anthracis and other pathogens of military and civilian interest. Identified cyclic or...
7538228 Oxazoline ligands for asymmetric catalysis  
A chiral ligand represented by the formula and its enantiomer: wherein A, X, Y and Z are as defined in the specification is provided. Also provided is a process of making the chiral ligands and...
7536913 Rigidly mounted underwater acoustic inertial vector sensor  
An underwater acoustic sensor is designed for attachment to a rigid or semi-rigid mounting structure. The sensor includes an outer casing and a secondary casing spaced therefrom. A compliance layer...
7534902 Fluorescence assays with improved sensitivity  
Latent fluorescent compounds, comprising a fluorescent molecule with one or more blocking groups attached and optionally one or more urea-containing groups are provided. The urea-containing group...
7531698 Tetraphosphorus ligands for catalytic hydroformylation and related reactions  
Tetraphosphorous ligands are combined with transition metal salts to form catalysts for use in hydroformylation, isomerization-hydroformylation, hydrocarboxylation, hydrocyan-ation,...
US20090118145 METHOD FOR PRODUCING PROPPANT USING A DOPANT  
A method for producing sintered pellets and sintered pellets produced therefrom including mixing a dopant with water and kaolin clay to form substantially round and spherical green pellets and...
US20090117081 PARVOVIRUS METHODS AND COMPOSITIONS FOR KILLING NEOPLASTIC CELLS  
According to the invention, parvoviruses such as the adeno-associated virus Type 2 (AAV2) are found to be oncolytic, selectively mediating apoptosis in cancer cells and their precursers, while...
US20090108507 Method for manufacture of transparent ceramics  
The disclosed invention relates to a method of manufacture of transparent ceramics such as yttrium aluminum garnet by tape casting. The method entails forming a mixture of ceramic oxide, dispersant...
7524390 Fixture and method of holding and debonding a workpiece with the fixture  
A fixture for holding a workpiece during a manufacturing process includes a base and a rod received by and moveable relative to the base. The rod includes a proximal end presenting a bonding...
7521932 Method and system for adjusting the fundamental symmetric mode of coupled high temperature superconductor coils  
The frequency of the fundamental symmetric mode of two or more coupled essentially identical high temperature superconductor coils can be tuned, with little degradation in Q, by mechanically...
7516759 Autonomous moving microstructures  
A microstructure includes a catalyst region, and a non-catalyst region proximate to the catalyst region. The catalyst region induces a chemical reaction of a fluid component when the microstructure...
7516640 Method and apparatus for forming a blank as a portion of the blank receives pulses of direct current  
A method is provided for forming a sheet metal blank or tubular blank in a metal forming tool, such as a sheet metal press or a media forming tool. The sheet metal press has an upper die and a...