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8185704 |
High performance real-time read-copy update
A technique for reducing reader overhead when referencing a shared data element while facilitating realtime-safe detection of a grace period for deferring destruction of the shared data element....
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US20120121512 |
MONOCLONAL ANTIBODIES AND THEIR USE
Isolated monoclonal antibodies are disclosed herein that specifically bind a cell surface antigen expressed on the human pancreatic endocrine cells or a subset thereof, and/or a precursor thereof....
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8180134 |
In vivo structural and flow imaging
Embodiments of the present invention include but are not limited to methods and systems for optical coherence imaging. A method for optical coherence imaging may comprise scanning a sample with an...
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US20120116187 |
METHOD AND APPARATUS FOR ASSESSMENT OF SLEEP DISORDERS
Embodiments provide systems, methods and apparatuses for monitoring the sleep of a subject in a home environment. In embodiments, load cells placed under bed supports may be coupled to a computing...
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US20120115904 |
COMPOUNDS HAVING ANTIPARASITIC OR ANTI-INFECTIOUS ACTIVITY
Compounds of formula I: or formula II: or a pharmaceutically acceptable salt of formula I or formula II, wherein:R1 is H, hydroxyl, alkoxy, acyl, alkyl, cycloalkyl, aryl, or heteroaryl;R2 is methyl...
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US20120114936 |
THIN LAYER SUBSTRATE COATING AND METHOD OF FORMING SAME
Embodiments of the present invention relate to coating deposition and coatings for dental and orthopedic devices that provide prevention or reduction of ion leakage and, in some situations,...
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US20120107341 |
METHODS FOR PRODUCING AN IMMUNE RESPONSE TO TUBERCULOSIS
Methods for producing an immune response to Mycobacterium tuberculosis (Mtb) are disclosed herein. In several examples, the immune response is a protective immune response. In additional...
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8171562 |
System and methods for protecting against denial of service attacks
A system and methods utilizing the network layer to provide security in distributed computing systems in order to thwart denial of service attacks. The system and methods of the present invention...
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8158435 |
Tandem mass spectrometry for detecting and/or screening for conditions associated with altered sterols
Embodiments of the present invention provide for detecting and/or screening for conditions associated with altered sterols by derivatization of sterols to provide suitable sensitivity and...
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US20120088255 |
HER-2 BINDING ANTAGONISTS
There is disclosed a pharmaceutical composition for treating solid tumors that overexpress HER-2, comprising an agent selected from the group consisting of (a) an isolated polypeptide having from...
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8147824 |
Immunomodulatory properties of multipotent adult progenitor cells and uses thereof
Isolated cells are described that are not embryonic stem cells, not embryonic germ cells, and not germ cells. The cells can differentiate into at least one cell type of each of at least two of the...
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US20120077186 |
USE OF CYSTEINE-DERIVED SUPPRESSOR TRNAS FOR NON-NATIVE AMINO ACID INCORPORATION
Disclosed herein are compositions and methods for incorporating non-native amino acids into a single polypeptide. In one example, an isolated modified suppressor tRNA is disclosed that includes the...
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US20120063665 |
METHOD AND APPARATUS FOR QUANTITATIVE IMAGING OF BLOOD PERFUSION IN LIVING TISSUE
Embodiments provide methods and systems for imaging, and, more specifically, to a method and apparatus for quantitative imaging of blood perfusion in living tissue. Some embodiments are directed to...
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8124397 |
Inactivating pathogens with oxidizing agents for vaccine production
The present disclosure provides methods for producing a vaccine composition containing a pathogen that is rendered noninfectious by exposure to hydrogen peroxide. The methods disclosed herein are...
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8124180 |
Thin layer substrate coating and method of forming same
Embodiments of the present invention relate to coating deposition and coatings for dental and orthopedic devices that provide prevention or reduction of ion leakage and, in some situations,...
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US20120045755 |
HER-2 BINDING ANTAGONISTS
There is disclosed a pharmaceutical composition for treating solid tumors that overexpress HER-2, comprising an agent selected from the group consisting of (a) an isolated polypeptide having from...
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8108696 |
Optimizing non-preemptible read-copy update for low-power usage by avoiding unnecessary wakeups
A technique for low-power detection of a grace period following a shared data element update operation that affects non-preemptible data readers. A grace period processing action is implemented...
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8101192 |
Methods for producing an immune response to tuberculosis
Methods for producing an immune response to Mycobacterium tuberculosis (Mtb) are disclosed herein. In several examples, the immune response is a protective immune response. In additional...
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US20120014881 |
METHODS FOR DETECTING A MYCOBACTERIUM TUBERCULOSIS INFECTION
Methods for detecting an infection with Mycobacterium tuberculosis (Mtb) in a subject are disclosed. The methods include detecting the presence of CD8+ T cells that specifically recognize an Mtb...
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8097428 |
Monoclonal antibodies and their use
Isolated monoclonal antibodies are disclosed herein that specifically bind a cell surface antigen expressed on the human pancreatic endocrine cells or a subset thereof, and/or a precursor thereof....
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US20120010237 |
COMPOUNDS HAVING ANTIPARASITIC OR ANTI-INFECTIOUS ACTIVITY
A method for inhibiting a parasitic or infectious disease in a subject, wherein the parasitic or infectious disease is selected from one caused by Eimeria sp., Babesia sp., Theileria sp. or...
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8093216 |
Method of treating cancer by inhibition of p95HER-2 production
There is disclosed an initial identification of an N-terminally truncated HER-2/neu product. This product is a 95 kDa polypeptide having in vitro kinase activity (as determined by western...
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8089408 |
Robust low-frequency spread-spectrum navigation system
Methods and apparatus are described for a navigation system. A process includes providing a plurality of transmitters distributed throughout a desired coverage area; locking the plurality of...
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US20110313262 |
METHOD AND APPARATUS FOR PREVENTION OF APNEA
Embodiments provide a continuous monitor of a patient's oxygenation and/or respiration coupled to a device configured to stimulate the patient's respiratory drive and/or summon medical assistance....
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8071553 |
Method and peptide for regulating cellular activity
Method and peptide for regulating cellular activity includes a panel of synthesized peptides that have biological effects on inhibiting or enhancing cellular activity. Selected peptides can be used...
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8068990 |
Diagnosis of intra-uterine infection by proteomic analysis of cervical-vaginal fluids
The invention concerns the identification of proteomes of biological fluids and their use in determining the state of maternal/fetal conditions, including maternal conditions of fetal origin,...
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US20110288136 |
FLAVIVIRUS INHIBITION BY SULTAMS AND RELATED COMPOUNDS
Disclosed herein are compounds, compositions and methods for treating or ameliorating flavivirus infections. This is particularly important because the present disclosure provides methods for...
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8058233 |
Modification of feeding behavior using PYY and GLP-1
Methods are disclosed for decreasing calorie intake, food intake, and appetite in a subject. The methods include peripherally administering PYY or an agonist thereof and GLP-1 or an agonist thereof...
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8057398 |
Method, system, and apparatus for cardiovascular signal analysis, modeling, and monitoring
Disclosed embodiments of the invention include a method, system, and apparatus to monitor cardiovascular signals such as arterial blood pressure (ABP), pulse oximetry (POX), and intracranial...
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8053197 |
Methods for detecting and treating autoimmune disorders
The present disclosure relates to methods for inhibiting an autoimmune disease by administering to a subject a therapeutically effective amount of a composition that increases FOXP3 expression,...
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8053181 |
Methods for detecting a Mycobacterium tuberculosis infection
Methods for detecting an infection with Mycobacterium tuberculosis (Mtb) in a subject are disclosed. The methods include detecting the presence of CD8+T cells that specifically recognize an Mtb...
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US20110262479 |
RECOMBINANT MHC MOLECULES USEFUL FOR MANIPULATION OF ANTIGEN-SPECIFIC T-CELLS
Two-domain MHC polypeptides useful for manipulation of antigen-specific T-cells are disclosed. These polypeptides include MHC class II-based molecules that comprise covalently linked β1 and α1 d...
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US20110244450 |
PRIMATE TOTIPOTENT AND PLURIPOTENT STEM CELLS PRODUCED BY SOMATIC CELL NUCLEAR TRANSFER
Purified totipotent stem cells and pluripotent stems cells derived by somatic cell nuclear transfer are disclosed herein, as well as cell lines, multipotent cells and differentiated cells produced...
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8030004 |
Cell free screening assay and methods of use
Methods are disclosed for identifying agents for the treatment of cancer and/or Fanconi anemia using Xenopus egg cell free extracts from which the endogenous DNA has been removed. The assays and...
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US20110236507 |
INHIBITION OF DNA POLYMERASES TO AUGMENT CHEMOTHERAPEUTIC AND ANTIMICROBIAL AGENTS
Disclosed herein is the identification of human DNA polymerase κ (pol κ) as the polymerase that mediates repair of DNA containing interstrand cros slinks (ICLs). The mechanism of action of a n...
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D646043 |
Bicycle gutter
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US20110228907 |
HEAD AND NECK RADIATION LOCALIZATION USING ORAL APPLIANCE
In various embodiments, methods, apparatuses, and systems for accurate patient positioning and motion tracking before and/or during head and neck radiation therapy, such as intensity modulated...
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8020160 |
User-level read-copy update that does not require disabling preemption or signal handling
A user-level read-copy update (RCU) technique. A user-level RCU subsystem executes within threads of a user-level multithreaded application. The multithreaded application may include reader threads...
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US20110218230 |
NATRIURETIC PEPTIDE RELATED FRAGMENT IN CARDIOVASCULAR DISEASE
This disclosure provides an intracellular fragment of natriuretic peptide receptor A (NPRA), referred to herein as soluble natriuretic peptide receptor-related fragment (sNRF). It is shown herein...
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US20110213278 |
MOVEMENT MONITORING SYSTEM AND APPARATUS FOR OBJECTIVE ASSESSMENT OF MOVEMENT DISORDERS
Disclosed embodiments include a movement monitoring system and apparatus for objective assessment of movement disorders of a subject, comprising (a) one or more movement monitors, and (b) a...
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US20110213277 |
SYSTEM, METHOD, AND APPARATUS FOR OBJECTIVE ASSESSMENT OF MOTOR SIGNS AT THE EXTREMITIES
Disclosed embodiments include a system for objective assessment of motor signs at the extremities that comprises (a) a device for objective motor sign measurement, (b) a test protocol defining a...
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8003674 |
Flavivirus inhibition by sultams and related compounds
Disclosed herein are compounds, compositions and methods for treating or ameliorating flavivirus infections. This is particularly important because the present disclosure provides methods for...
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US20110201917 |
METHOD AND APPARATUS USING MAGNETIC RESONANCE IMAGING FOR CANCER IDENTIFICATION
Embodiments provide a Magnetic Resonance Imaging (MRI) technique and optionally software—collectively referred to as the “shutter-speed” model—to analyze image data of cancer patients. Embodim...
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US20110195064 |
SURVIVAL PREDICTOR FOR DIFFUSE LARGE B CELL LYMPHOMA
The invention provides methods and materials related to a gene expression-based survival predictor for diffuse large B cell lymphoma (DLBCL) patients.
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US20110194075 |
METHOD AND APPARATUS FOR VISUAL FIELD MONITORING
Embodiments provide methods and systems for the modeling and analysis of visual fields. Methods for global and regional measurement of visual sensitivity and quantification of field loss are...
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US20110189174 |
COMPOSITIONS AND METHODS FOR TREATING, REDUCING, AMELIORATING, ALLEVIATING, OR INHIBITING PROGRESSION OF, PATHOGENIC OCULAR NEOVASCULARIZATION
A composition for treating, reducing, ameliorating, alleviating, or inhibiting the progression of, pathological ocular neovascularization comprises an integrin or vitronectin receptor antagonist...
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7981628 |
Monoclonal antibodies and their use
Isolated monoclonal antibodies are disclosed herein that specifically bind a cell surface antigen expressed on the human pancreatic endocrine cells or a subset thereof, and/or a precursor thereof....
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US20110165080 |
MONOCLONAL ANTIBODIES AND THEIR USE
Isolated monoclonal antibodies are disclosed herein that specifically bind a cell surface antigen expressed on the human pancreatic endocrine cells or a subset thereof, and/or a precursor thereof....
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7972849 |
Primate pluripotent stem cells produced by somatic cell nuclear transfer
Purified totipotent stem cells and pluripotent stems cells derived by somatic cell nuclear transfer are disclosed herein, as well as cell lines, multipotent cells and differentiated cells produced...
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7972607 |
Attenuated francisella and methods of use
Francisella tularensis is the bacterial pathogen that causes tularemia in humans and a number of animals. To date, no approved vaccine exists for this widespread and life-threatening disease. The...
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