Patents and Patent Applications from Ohio State University


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US20120126920 LAMINATE COMPOSITE AND METHOD FOR MAKING SAME  
An organic-based magnet is formed by molecular layer deposition (MLD) of a first compound and MLD of a second compound. The first or second compound containing a metal-containing compound. The...
8183365 Synthetic method for ceratamine A and B and analogs thereof  
Methods are provided for preparing compounds of the general formula (I) wherein X1 is an aryl hydrocarbon group optionally substituted with one or more groups independently selected from —R, —...
US20120121626 Chimeric VEGF Peptides  
Compositions for and methods of treating patients with malignancies associated with overexpression of VEGF, particularly ovarian cancer are provided herein. The compositions include but are not...
8177890 Stable supported Pd-alloy membranes  
A Pd alloy membrane and method of making are described.
US20120116307 DIFFUSION DELIVERY SYSTEMS AND METHODS OF FABRICATION  
The invention generally relates to diffusion delivery systems and more particularly to high precision nanoengineered devices for therapeutic applications. The device contains diffusion areas that...
8172969 Apparatus and method for ultrasonic processing of laminates  
A method for ultrasonic debulking a composite laminate includes the steps of defining a path across the laminate, the path having a starting location and an ending location and applying a force to...
8172900 Microsensor system for application in biomechanics  
A sensing system and method to detect and determine magnitude and direction of ciliary body movement within an eye of a patient is disclosed. The invention comprises a permanent magnet (PM)...
US20120108823 ANTI-FRANCISELLA AGENTS  
A series of celecoxib derivatives defined by Formula I: were prepared and evaluated for their ability to inhibit the gram-negative bacteria Francisella tularensis. Pharmaceutical compositions...
US20120103949 LASER-INDUCED METALLURGICAL BONDING DRIVEN WITHOUT CONTACT  
A laser, aimed at a flyer plate tab, causes optical energy to be directed at the tab, specifically, at a top surface thereof. Energy impacting the tab accelerates the tab into an impact with a...
US20120100068 Anti-CD74 Immunoconjugates and Methods of Use  
Disclosed are compositions that include anti-CD74 immunoconjugates and optionally a therapeutic and/or diagnostic agent. In preferred embodiments, the immunoconjugates comprise one or more...
8163263 Catalyst for the growth of carbon single-walled nanotubes  
Methods and processes for synthesizing single-wall carbon nanotubes are provided. A carbon precursor gas is contacted with metal catalysts deposited on a support material. The metal catalysts are...
US20120095443 NANOCHANNELED DEVICE AND RELATED METHODS  
A capsule configured for in vivo refilling of a thereapeutic agent. In certain embodiments, the capsule may contain methotrexate.
US20120085353 JOINT STABILITY ARRANGEMENT AND METHOD  
The stability of an animal joint, especially a knee, is assessed with an arrangement having track arranged about perpendicular to the axis of the distal portion; a cart slidably engaged to the...
8153680 Alkyl indole-3-carbinol-derived antitumor agents  
Compounds and methods for treating cancer or inducing apoptosis in proliferating cells. The compounds are shown in formula I: wherein X is selected from hydroxyl, thiol, and amino; Y is selected...
US20120083684 DIGITAL DISTANCE MEASURER FOR NERVE CONDUCTION STUDIES  
Nerve conduction studies (NCS) are used to diagnose many types of disorders and are being employed more and more frequently. Current methods for distance measurement during a NCS are manual and...
8148069 MicroRNA-based methods and compositions for the diagnosis, prognosis and treatment of solid cancers  
The present invention provides novel methods and compositions for the diagnosis and treatment of solid cancers. The invention also provide methods of identifying inhibitors of tumorigenesis.
US20120077700 METHOD OF DIAGNOSING POOR SURVIVAL PROGNOSIS COLON CANCER USING miR-29a  
The present invention provides novel methods and compositions for the diagnosis and treatment of colon cancers. In particular, the present invention provides diagnostics and prognostics for colon...
US20120077699 METHOD OF DIAGNOSING POOR SURVIVAL PROGNOSIS COLON CANCER USING miR-103-2  
The present invention provides novel methods and compositions for the diagnosis and treatment of colon cancers. In particular, the present invention provides diagnostics and prognostics for colon...
8143337 Method of preparing a composite with disperse long fibers and nanoparticles  
A composite material having polymeric resin with disperse phases of reinforcing fibers and nanoparticle materials and its manufacture is disclosed herein. The nanoparticles may be bound together...
US20120071045 MARINE PROPULSION SYSTEM  
A marine propulsion system comprising, in one embodiment: a fuel-filled tank; an air compressor that generates compressed air; an engine that receives fuel from the tank, wherein the air compressor...
8137751 Hierarchical structures for superhydrophobic surfaces and methods of making  
Embodiments of methods of making superhydrophobic structures comprise depositing a polymer mold onto a silicon surface comprising a plurality of microasperities, removing the polymer mold after the...
US20120065098 METHOD OF PREDICTING CHEMOTHERAPY EFFECTIVENESS IN COLON ADENOCARCINOMA PATIENTS, USING MIR-21  
The present invention provides novel methods and compositions for the diagnosis and treatment of colon cancers. In particular, the present invention provides diagnostics and prognostics for colon...
US20120065097 METHOD OF DIAGNOSING POOR SURVIVAL PROGNOSIS COLON CANCER USING miR-106a  
The present invention provides novel methods and compositions for the diagnosis and treatment of colon cancers. In particular, the present invention provides diagnostics and prognostics for colon...
8133828 Lanthanum oxide-doped glass-ceramics  
Glass-ceramic compositions exhibiting high reliability and tensile strength are described. The compositions can include crystal phases including roedderite and/or potassium fluorrichterite. The...
US20120058915 METHOD OF DIAGNOSING POOR SURVIVAL PROGNOSIS COLON CANCER USING miR-10a  
The present invention provides novel methods and compositions for the diagnosis and treatment of colon cancers. In particular, the present invention provides diagnostics and prognostics for colon...
US20120058914 METHOD OF DIAGNOSING POOR SURVIVAL PROGNOSIS COLON CANCER USING miR-203  
The present invention provides novel methods and compositions for the diagnosis and treatment of colon cancers. In particular, the present invention provides diagnostics and prognostics for colon...
US20120058913 METHOD OF DIAGNOSING POOR SURVIVAL PROGNOSIS COLON CANCER USING miR-16b  
The present invention provides novel methods and compositions for the diagnosis and treatment of colon cancers. In particular, the present invention provides diagnostics and prognostics for colon...
US20120058912 METHOD OF DIAGNOSING POOR SURVIVAL PROGNOSIS COLON CANCER USING let-7g  
The present invention provides novel methods and compositions for the diagnosis and treatment of colon cancers. In particular, the present invention provides diagnostics and prognostics for colon...
US20120058911 METHOD OF DIAGNOSING POOR SURVIVAL PROGNOSIS COLON CANCER USING miR-181b  
The present invention provides novel methods and compositions for the diagnosis and treatment of colon cancers. In particular, the present invention provides diagnostics and prognostics for colon...
US20120058910 METHOD FOR DIAGNOSING ACUTE LYMPHOMIC LEUKEMIA (ALL) USING MIR-125b  
Disclosed are compositions and methods for reducing the proliferation of ALL cancer cells through targeted interactions with ALL1 fusion proteins.
8131043 Method and apparatus for detecting interventricular dyssynchrony  
Several embodiments of a method and apparatus for detecting interventricular dyssynchrony are provided. In one embodiment, the apparatus includes an image segment processor and an image classifier....
US20120054905 Marker Assisted Selection for Coupling Phase Resistance to Tomato Spotted Wilt Virus and Late Blight in Tomato  
A Solanum lycopersicum plant including within its genome at least one Tomato Spotted Wilt Virus (TSWV) resistance allele and at least one Phytophthora infestans resistance allele. The resistance...
US20120053208 Curcumin Analogs as Dual JAK2/STAT3 Inhibitors and Methods of Making and Using the Same  
Curcumin analogues and methods of making and using the same are disclosed.
US20120051615 METHOD FOR SHARING DATA BETWEEN DATA SETS WITH DIFFERENTIALLY ENCODED DATA  
An exemplary embodiment of the present invention includes a method for increasing temporal resolution in Phase Contrast (PC) MR imaging. The increased temporal resolution may be obtained by reusing...
US20120051597 GAZE TRACKING MEASUREMENT AND TRAINING SYSTEM AND METHOD  
Many athletic endeavors require focus on a moving object and subsequent coordination of bodily movement either in response to movement of the object or in an attempt to manipulate the object....
US20120046194 METHOD FOR DIAGNOSING ACUTE LYMPHOMIC LEUKEMIA (ALL) USING MIR-146a  
Disclosed are compositions and methods for reducing the proliferation of ALL cancer cells through targeted interactions with ALL1 fusion proteins.
US20120046193 METHOD FOR DIAGNOSING ACUTE LYMPHOMIC LEUKEMIA (ALL) USING MIR-222  
Disclosed are compositions and methods for reducing the proliferation of ALL cancer cells through targeted interactions with ALL1 fusion proteins.
US20120046192 METHOD FOR DIAGNOSING ACUTE LYMPHOMIC LEUKEMIA (ALL) USING MIR-221  
Disclosed are compositions and methods for reducing the proliferation of ALL cancer cells through targeted interactions with ALL1 fusion proteins.
US20120045778 ELISA FOR HAPTOGLOBIN-MATRIX METALLOPROTEINASE 9 COMPLEX AS A DIAGNOSTIC TEST FOR CONDITIONS INCLUDING ACUTE INFLAMMATION  
A method for detecting a haptoglobin-matrix metalloproteinase 9 (Hp-MMP9) complex in a biological sample. The sample includes incubating the biological sample with a capture reagent immobilized on...
8119101 Anti-CD74 immunoconjugates and methods of use  
Disclosed are compositions that include anti-CD74 immunoconjugates and optionally a therapeutic and/or diagnostic agent. In preferred embodiments, the immunoconjugates comprise one or more...
US20120040347 Polymorphism in CYP3A4 Gene Affecting Drug Metabolizing and Uses Thereof  
A method for predicting a subject's risk factors for CYP3A4-related disorders includes detecting the allelic status of a SNP in a nucleic acid sample of the subject.
8114675 Room temperature CO sensor and method of making same  
Described are CO sensors, methods for making the CO sensors, and methods for using the CO sensors. An exemplary CO sensor includes a ruthenium oxide present in a form having one or more surfaces, a...
US20120035457 ELECTROMAGNETIC SYSTEM AND METHOD  
Differences of electromagnetic (EM) properties between healthy and cancerous tissues allow detection of abnormal conditions occurring in a tissue of an animal, for example, intra-operative cancer...
US20120031833 SYSTEMS, COMPOSITIONS, AND METHODS FOR FLUID PURIFICATION  
Disclosed herein are membranes comprising a substrate, a support layer, and a selective layer. In some embodiments the membrane may further comprise a permeable layer. Methods of forming membranes...
8110657 Polypeptides and polynucleotides for enhancing immune reactivity to HER-2 protein  
Compositions for stimulating the immune system and for treating malignancies associated with overexpression of the HER-2 protein are provided. Such compositions include immunogenic epitopes of the...
8110562 Selective androgen receptor modulators, analogs and derivatives thereof and uses thereof  
This invention provides nuclear hormone receptor binding compounds, compositions comprising the same and methods of uses thereof in treating a variety of diseases or conditions in a subject,...
US20120028833 MiR-25-BASED METHODS FOR THE DIAGNOSIS AND PROGNOSIS OF ACUTE MYELOID LEUKEMIA (AML)  
The present invention provides novel methods and compositions for the diagnosis, prognosis and treatment of acute myeloid leukemia (AML). The invention also provides methods of identifying anti-AML...
US20120028832 MiR-182-, miR-191, miR-199a-BASED METHODS FOR THE DIAGNOSIS AND PROGNOSIS OF ACUTE MYELOID LEUKEMIA (AML)  
The present invention provides novel methods and compositions for the diagnosis, prognosis and treatment of acute myeloid leukemia (AML).
US20120028831 MiR-29-BASED METHODS FOR THE DIAGNOSIS AND PROGNOSIS OF ACUTE MYELOID LEUKEMIA (AML)  
The present invention provides novel methods and compositions for the diagnosis, prognosis and treatment of acute myeloid leukemia (AML). The invention also provides methods of identifying anti-AML...
US20120027753 MicroRNAs in Never-Smokers and Related Materials and Methods  
The present invention provides novel methods and compositions for the diagnosis, prognosis and treatment of lung cancer in never-smokers. The invention also provides methods of identifying...