Patents and Patent Applications from Ohio State University


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US20170351027 PATTERNED ION-SLICED CRYSTAL FOR HYBRID INTEGRATED PHOTONICS  
An example method of forming a deterministic thin film from a crystal substrate is described herein. The method can include implanting ions into a surface of the crystal substrate to form a thin...
US20170348409 COMPOSITIONS AND METHODS RELATED TO VIRAL VACCINES  
Provided herein are methods and compositions relating to Infectious Bursal Disease Virus (IBDV), and vaccines for treatment and prevention thereof.
9833523 Pharmacokinetic determination of intravitreal agents  
Compositions and methods for evaluating a pharmacokinetic property of an ophthalmic agent administered by intravitreal injection are provided.
9833416 Oligonucleotide lipid nanoparticle compositions, methods of making and methods of using the same  
Compositions for inhibiting oligonucleotide activity in vitro or in vivo to a cell that are formulated with at least one oligonucleotide encapsulated in a lipid nanoparticle, methods of making,...
US20170341017 MEMBRANES FOR FLUID SEPARATION  
Membranes, methods of making the membranes, and methods of using the membranes are described herein. The membranes can comprise a gas permeable support and a continuous phase comprising a...
US20170340715 Materials and Methods Useful For Treating Glioblastoma  
The present invention provides compositions and methods useful for treating cancers such as glioblastoma. SapC-DOPS was found to be synergistically effective at inducing cell death when...
US20170335472 Catalytic Materials and Methods of Making and Using Thereof  
Iron-containing mixed-phase metal oxides are described. The mixed-phase metal oxides can exhibit electrocatalytic and/or photo-electrocatalytic activity towards reducing reactions, such as the...
US20170333493 PROBIOTIC BACTERIA FOR THE PREVENTION AND TREATMENT OF SALMONELLA  
As disclosed herein, fructose-asparagine (F-Asn) is a primary nutrient utilized during Salmonella-mediated gastroenteritis. Engineered bacteria are disclosed that can compete with Salmonella for...
US20170333389 Method of Ameliorating Clotting Pathologies and Related Materials and Methods  
Methods for reducing blood clotting in a subject are provided, including methods to reduce the risk of and/or treat blot clotting pathologies. Also provided are compositions useful to reduce the...
US20170332938 METHODS FOR CO-IMAGING TISSUE STIFFNESS AND BLOOD FLOW IN AN MRI SCAN  
Techniques for co-imaging tissue stiffness and blood flow using a single MRI scan are disclosed. The methods use a combined gradient waveform that provides adequate sensitivity for concurrent...
US20170332937 HYDRAULICALLY-POWERED AND HYBRID HYDRAULIC-PNEUMATIC SYSTEMS AND METHODS FOR ACHIEVING MAGNETIC RESONANCE ELASTOGRAPHY  
Systems and methods are described for inducing tissue vibration for magnetic resonance elastography is described. The system includes a hydraulic drive component that is mechanically linked to a...
US20170328904 TETHERED LIPOPLEX NANOPARTICLE BIOCHIPS AND METHODS OF USE  
Disclosed are compositions and methods for the use of lipoplex nanoparticle chips and arrays in the detection of/diagnosis of a disease or condition.
9819488 Generation of encryption keys based on location  
A method of generating an encryption key including determining, by a processor, a distance between a first node and a second node, and generating, by the processor, a first encryption key based on...
9816086 Dose and location controlled drug/gene/particle delivery to individual cells by nanoelectroporation  
A simple and low cost method of producing sealed arrays of laterally ordered nanochannels interconnected to microchannels of tunable size, over large surface areas, is disclosed. The method...
US20170323460 IMAGE COLOR DATA NORMALIZATION AND COLOR MATCHING SYSTEM FOR TRANSLUCENT MATERIAL  
A shade selection program is disclosed that predicts the shade choice with the smallest CIEDE2000 color difference for dental composite resin restorations when given a backing and target shade. By...
US20170320941 CS1-SPECIFIC CHIMERIC ANTIGEN RECEPTOR ENGINEERED IMMUNE EFFECTOR CELLS  
Disclosed herein are chimeric antigen receptors (CAR) that can specifically recognize tumor-associated antigens (TAA) on multiple myeloma (MM) cells. Also disclosed are immune effector cells, such...
9809810 Galvanotaxis assay for quantitative assessment of the metastatic potential of cancer cells  
An apparatus and method for accelerating and/or inhibiting the migration of cells by applying a time-varying magnetic field to induce eddy currents that promote electrotaxis (galvanotaxis) of...
9808758 Wet scrubber apparatus for ammonia capture  
A method for removing ammonia from a gas stream divides the gas steam into a plurality of separate gas streams and sprays a dilute acid solution into the streams. The acid solution is aqueous...
US20170315203 PERFORATOR PHASE CONTRAST ANGIOGRAPHY (pPCA)  
The present disclosure is directed to methods and systems for fusing Phase Contrast Angiography (PCA) with anatomic images to create a perforator PCA (pPCA) data set. In the pPCA) method, vascular...
US20170314033 HERBICIDE-RESISTANT TARAXACUM KOK-SAGHYZ AND TARAXACUM BREVICORNICULATUM  
The invention provides the genetically manipulated herbicide-resistant rubber producing dandelion plants and seed of said plants. Another aspect of the invention comprises progeny plants, or...
US20170313763 COMPOSITIONS AND METHODS RELATED TO VIRAL VACCINES  
Provided herein are methods and compositions relating to Infectious Bursal Disease Virus (IBDV), and vaccines for treatment and prevention thereof.
9804423 On-chip optical polarization controller  
An example optical polarization controller can include a substantially planar substrate and a waveguide unit cell formed on the substantially planar substrate. The waveguide unit cell can include...
9803802 Method and system for compressing gas using a liquid  
A method of compressing gas includes maintaining a volume of gas at a first pressure within a first chamber. Pressurized liquid is forced into the first chamber through a nozzle having a curved...
US20170308782 STRETCHABLE BROAD IMPEDANCE BANDWIDTH RFID DEVICES  
According to the embodiments described herein, a stretchable RFID device can include an RFID chip and an RFID antenna. The RFID antenna can be electrically coupled and mechanically attached to the...
US20170307955 DEVICES AND METHODS FOR IMPLEMENTING AN OPTICAL SWITCHING ENGINE  
Disclosed herein are various improvements in optical switching engines. In one aspect, a range of switching engines includes various multiple bounce, multiple image devices, such as, for example,...
US20170307748 SYSTEMS AND METHODS FOR MEASURING WAVE FIELDS OF A BODY OF WATER  
This disclosure relates to systems and methods for measuring wave fields of a body of water. A system can include a radiation source and an antenna that can cooperate with the radiation source to...
US20170306337 BIOPRODUCT FORMATION FROM A PLASMID ADDICTION SYSTEM IN THE ABSENCE OF CO-INDUCERS AND ANTIBIOTICS  
Described herein are plasmid addiction systems comprising a host cell comprising one or more inactivated host cell essential genes; and a plasmid comprising one or more plasmid essential genes...
US20170305959 ANTILEISHMANIAL COMPOSITIONS AND METHODS OF USE  
In one aspect, the invention relates methods and compositions for treating parasitic diseases, for example, leishmaniasis. In a further aspect, the compounds of the methods and compositions are...
US20170304571 INTUBATION WITH AUDIOVIBRATORY GUIDANCE  
Systems and methods are provided for inserting an endoscope through an anatomical cavity to a target site. A speaker is positioned externally proximate to a patient and the endoscope is inserted...
US20170304383 SMALL MOLECULE RAS INHIBITORS  
Disclosed herein are novel compounds that are Ras inhibitors. Also disclosed are compositions comprising the compounds and methods of using the compounds in treating various diseases. In another...
US20170304261 SILVESTROL, SILVESTROL ANALOGS AND USES THEREOF  
Disclosed herein are treatment methods, vaccination methods, compositions, co-therapeutic methods, combination therapeutic compositions and kits comprising silvestrol and silvestrol analogs alone...
9796967 Compositions related to controllable intervening protein sequences (CIPS) comprising reversible zinc-binding motifs and inteins  
Disclosed are compositions comprising an engineered intein designed such that the self-cleaving activity of the intein can be modulated by a zinc-binding motif as well as methods and systems for...
US20170298446 BIOMARKERS OF BRUTON TYROSINE KINASE INHIBITOR RESISTANCE  
Biomarkers and methods are disclosed that identify patients being treated with a BTK inhibitor that have acquired a mutation that will cause resistance to the BTK inhibitor. Therefore, also...
US20170298395 AUTOTROPHIC HYDROGEN BACTERIA AND USES THEREOF  
In an aspect, the invention relates to compositions and methods production of n-butanol by aerobic hydrogen bacteria. This abstract is intended as a scanning tool for purposes of searching in the...
9791396 Space adaptive reconstruction technique for adaptive electrical capacitance volume tomography  
A capacitance system having a capacitance sensor provides a high resolution Spatial-Adaptive Reconstruction Technique (SART) for use with Adaptive Electrical Capacitance Volume Tomography (AECVT)....
US20170291253 HYBRID STRUCTURES FOR JOINING OF METALS AND CONTINUOUS FIBER MATERIALS  
A transition structure includes a metallic portion, a fiber portion including a plurality of tows embedded within the metallic portion and extending out from the metallic portion forming a fabric,...
9783513 STAT3 inhibitors and their anticancer use  
In one aspect, the invention relates to substituted 6-amino-5,8-dioxo-5,8-dihydronaphthalene-1-sulfonamide analogs and derivatives thereof, substituted 4-amino-5H-naphtho[1,8-cd]isothiazol-5-one...
9782176 Collapsible anvil head and stapling apparatus  
Various implementations of the invention provide for a one-piece surgical stapling apparatus that includes a stapler head and an anvil head assembly. The anvil head assembly is tiltable between a...
US20170281740 SERODIAGNOSIS OF SALMON POISONING DISEASE  
Neorickettsia helminthoeca is an obligate intra-cytoplasmic bacterium that causes salmon poisoning disease (SPD), an acute, febrile, fatal disease of dogs. Disclosed are compositions and methods...
US20170281723 IMPROVED PEPTIDYL CALCINEURIN INHIBITORS  
Improved calcineurin inhibitors and methods of using these improved calcineurin inhibitors to inhibit calcineurin-NFAT signaling in cells and in subjects are disclosed.
9777920 Oxygen carrying materials  
In accordance with one embodiment of the present disclosure, an oxygen carrying material may include a primary active mass, a primary support material, and a secondary support material. The oxygen...
9777265 Non-contact method for accelerating wound healing using an electromagnetic coil to induce an electric field transverse to an axis of the wound  
A method for accelerating the migration of cells by applying a time-varying magnetic field to induce eddy currents that promote electrotaxis (galvanotaxis) of cells. The method of the present...
US20170279739 PREDICTIVE NETWORK SYSTEM AND METHOD  
A proactive networking system and method is disclosed. The network anticipates the user demands in advance and utilizes this predictive ability to reduce the peak to average ratio of the wireless...
US20170275625 Methods Of Inhibiting Tumorigenesis In Colon Adenocarcinoma And Compositions Therefor  
Described herein are methods and compositions for the treatment of colon cancers.
US20170273608 IONIC BARRIER FOR FLOATING GATE IN VIVO BIOSENSORS  
An ion-sensitive sensor includes a dielectric layer comprising Al2O3 having a functionalized surface configured to bond with an analyte. The ion-sensitive sensor is immersed in an electrolytic...
US20170272158 DRIVER SYSTEM WITH AN OPTICAL POWER BASED ISOLATED POWER SUPPLY  
The present invention relates to a driver system that can include an optical power based isolated power supply. The driver system can include an optical receiver that can be in communication with...
US20170269188 FOLDED TRANSDUCER ARRAY FOR COMPACT AND DEPLOYABLE WAVE-ENERGY GUIDING SYSTEM  
A wave energy guiding system is described that includes a structural substrate formed according to a folded-pattern topology including, for example, an origami-type folded-pattern topology such as...
US20170268591 DESIGNS AND MANUFACTURING METHODS FOR LIGHTWEIGHT HYPERDAMPING MATERIALS PROVIDING LARGE ATTENUATION OF BROADBAND-FREQUENCY STRUCTURE-BORNE SOUND  
A hyperdamping inclusion under constraint with large, broadband frequency damping properties is disclosed. The inclusion includes materials under near-buckling constraint such that fundamental...
9757432 Materials and methods useful for treating glioblastorna  
The present invention provides compositions and methods useful for treating cancers such as glioblastoma. SapC-DOPS was found to be synergistically effective at inducing cell death when...
9757213 Hybrid dental implant  
The present invention provides for a hybrid dental implant having a screw body with at least one external thread, which includes an upper portion with an open ceiling configured to receive one or...