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US20120129156 |
BARRIERS FOR FACILITATING BIOLOGICAL REACTIONS
The present invention relates to systems, devices, and methods for performing biological reactions. In particular, the present invention relates to the use of lipophilic, water immiscible, or...
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US20120128882 |
GEL POLYMER PEN LITHOGRAPHY
The disclosure relates to methods of printing indicia on a substrate using a tip array comprised of elastomeric, compressible gel polymers. The tip array can be prepared using conventional...
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US20120125492 |
Ultratough high-strength weldable plate steel
A transformation toughened, high-strength steel alloy useful in plate steel applications achieves extreme fracture toughness (Cv & gt 80 ft-lbs corresponding to KId=200 ksi.in ½) at strength ...
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US20120122799 |
CYCLIC PEPTIDE ANTITUMOR AGENTS
Cyclic peptide compounds and derivatives thereof having antitumor activity as shown by treatment of human melanoma, pancreatic, breast, prostate cancer cells.
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8176705 |
Nacre composites, methods of synthesis, and methods of use
The present invention relates to a novel composite structure with enhanced toughness, which incorporates features mimicked from nacre (mother of pearl). The structure can be used in many industrial...
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US20120116540 |
Prosthetic foot and method of making
A prosthetic foot is made by machining or molding a prosthetic foot profile to have a plurality of slots in and along the length of the forefoot region of the foot shape to achieve the appropriate...
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US20120100571 |
METHODS AND MATERIALS FOR NANOCRYSTALLINE SURFACE COATINGS AND ATTACHMENT OF PEPTIDE AMPHIPHILE NANOFIBERS THEREON
Biocompatible composites comprising peptide amphiphiles and surface modified substrates and related methods for attachment thereon.
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US20120100515 |
Fluoroscopy Simulator
An apparatus and machine for more realistically simulating fluoroscopy is disclosed. The apparatus includes a light source, cameras, an artificial lumen, and an access port. The artificial lumen...
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US20120097058 |
Multiplexed Biomolecule Arrays Made By Polymer Pen Lithography
Methods of patterning multiple biomolecules on a surface are disclosed. The method includes inking a polymer pen array, where tips are inked with selected inks comprising the biomolecules, and...
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8163347 |
High energy density nanocomposites and related methods of preparation
Disclosed are metal oxide-polymer composites having a substrate comprising a metal oxide component, an aluminum oxide component, and a metallocene olefin polymerization catalyst component coupled...
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8163345 |
Methods utilizing scanning probe microscope tips and products therefor or produced thereby
The invention provides a lithographic method referred to as “dip pen” nanolithography (DPN). Capillary transport of molecules from the SPM tip to the solid substrate is used in DPN to directly wri...
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US20120093885 |
THERAPEUTIC VESICLES
The present technology provides compositions of vesicles, uses of vesicles, and methods relating to vesicles. For example, provided herein are vesicles derived from stem cells for use in...
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US20120093784 |
COMPOSITIONS AND METHODS FOR CONTROLLING STEM CELL AND TUMOR CELL DIFFERENTIATION, GROWTH, AND FORMATION
The present invention relates to the use of self-assembling peptide amphiphiles to prevent tumor formation by transplanted stem cells. The present invention further relates to the use of...
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US20120093455 |
ULTRA-SENSITIVE ELECTRIC FIELD DETECTION DEVICE
An electric field detection device. In one embodiment, the electric field detection device includes an interferometer having a reference arm and an active arm. The reference arm comprises a first...
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8158658 |
Heteroaromatic selective inhibitors of neuronal nitric oxide synthase
Compounds selectively inhibiting neuronal nitric oxide synthase (nNos), such compounds of a formula wherein the variables are defined, herein.
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8158627 |
Compositions and treatments using pyridazine compounds and cholinesterase inhibitors
The invention relates to compositions, conjugates and methods comprising pyridazine compounds and cholinesterase inhibitors for modulation of cellular pathways (e.g., signal transduction pathways),...
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8157931 |
Case hardenable nickel-cobalt steel
An advanced secondary hardening carburized Ni—Co steel achieves an improved case hardness of about 68-69 Rc together with nominal core hardness of about 50 Rc.
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8156610 |
Writing assist device
A writing assist device includes a hand-receiving body having an exterior surface with a convex contour for ergonomically receiving the palm and/or fingers of the hand of a user from underneath and...
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8148071 |
Methods and compositions for isolating nucleic acid
The present invention relates to compositions and methods for isolating and purifying nucleic acid. In particular, the present invention relates to methods of isolating nucleic acid from cells for...
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US20120073438 |
Metal-organic frameworks for Xe/Kr separation
Metal-organic framework (MOF) materials are provided and are selectively adsorbent to xenon (Xe) over another noble gas such as krypton (Kr) and/or argon (Ar) as a result of having framework voids...
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8145760 |
Methods and systems for automatic inference and adaptation of virtualized computing environments
Certain embodiments of the present invention provide systems and method for automatic inference and adaptation of a virtualized computer environment. Certain embodiments of a system include a...
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8143181 |
Nonlinear optic glassy fiber, methods of making and applications of the same
A process for producing an optical glass fiber from crystal-glass phase material. In one embodiment, the process includes the step of providing a molten crystal-glass phase material in a container,...
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US20120071423 |
Heterotricyclic AMPA Receptor Antagonists for Treatment of Epilepsy, Pain, and Other Neurological Disorders and Diseases
Disclosed are heterotricyclic compounds, pharmaceutical compositions, methods of treatment, and methods for selectively antagonizing a glutamate receptor. The pharmaceutical compositions may...
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8138364 |
Transparent conducting oxide thin films and related devices
Transparent conducting oxide thin films having a reduced indium content and/or an increased tin content are provided. In addition, processes for producing the same, precursors for producing the...
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8138140 |
Self-assembling peptide amphiphiles and related methods for growth factor delivery
Amphiphilic peptide compounds comprising one or more epitope sequences for binding interaction with one or more corresponding growth factors, micellar assemblies of such compounds and related...
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8135243 |
Transparent conducting components and related electro-optic modulator devices
New electro-optic (EO) phase modulator devices and geometries, as can be constructed using a transparent conductive component.
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US20120059048 |
METHODS FOR DIAGNOSING AND TREATING SQUAMOUS CELL CARCINOMA UTILIZING miRNA-205 AND INHIBITORS THEREOF
Disclosed are diagnostic and therapeutic methods related to squamous cell carcinoma. In particular, the diagnostic methods relate to detecting miRNA-205, thereby diagnosing an aggressive form of...
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8131348 |
Systems, methods and apparatuses of elastic light scattering spectroscopy and low coherence enhanced backscattering spectroscopy
Systems, methods, and apparatuses of elastic light scattering spectroscopy and low-coherence enhanced backscattering spectroscopy are described here. An apparatus couple-able to a light source and...
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8128930 |
Anti-ADDL antibodies and uses thereof
The present invention relates to antibodies that differentially recognize multi-dimensional conformations of Aβ-derived diffusible ligands, also known as ADDLs. The antibodies of the invention can ...
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US20120052246 |
MESOSCALE PYRAMIDS, ARRAYS AND METHODS OF PREPARATION
Ordered, two-dimensional arrays of pyramidal particulates and related methods of preparation.
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8124583 |
Composition and method for self-assembly and mineralization of peptide-amphiphiles
The present invention is directed to a composition useful for making homogeneously mineralized self assembled peptide-amphiphile nanofibers and nanofiber gels. The composition is generally a...
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US20120046309 |
PYRIMIDINE-2,4,6-TRIONES FOR USE IN THE TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS
The present invention relates to the identification of inventive pyrimidine-2,4,6-triones (PYT compounds) and pharmaceutical compositions thereof for treating subjects with amyotrophic lateral...
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US20120042715 |
Advanced micro flow sensor
Multiple flow sensors in an array are provided to achieve wide dynamic range, low detection limit, and potentially low cost. Each flow sensor can measure the flow rate of surrounding fluid, among...
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8118949 |
Copper precipitate carburized steels and related method
A carburized and tempered hardened steel structure includes an iron based steel alloy including from about 3.7 to about 6 wt % copper, from 6 to about 10 wt % cobalt and from about 1 to about 10 wt...
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8114835 |
Self-assembling peptide amphiphiles for tissue engineering
The present invention provides for compositions and methods for creating self-assembled peptide amphiphile (PA) structures. In particular, the present invention provides for two and...
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8114834 |
Self-assembling peptide amphiphiles
The present invention provides for self-assembling peptide amphiphiles that are capable of forming nanofibers. In particular, the present invention provides for diacetylene peptide amphiphiles that...
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8114830 |
Polypeptoid pulmonary surfactants
The present invention provides spreading agents based on sequence-specific oligomers comprising a peptoid, a peptide-peptoid chimera, a retropeptoid or a retro(peptoid-peptide) chimera, and methods...
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8114599 |
Compositions and methods for free-solution conjugate nucleic acid analysis
The present invention provides compositions and methods for performing free-solution conjugate analysis of nucleic acid molecules. For example, the present invention provides multiplexed...
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8110432 |
Gate-planarized thin film transistor substrates and related methods of fabrication
Thin film transistor substrates with conductor components in conjunction therewith, and related methods of fabrication.
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8110125 |
Separation of carbon nanotubes in density gradients
The separation of single-walled carbon nanotubes (SWNTs), by chirality and/or diameter, using centrifugation of compositions of SWNTs in and surface active components in density gradient media.
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8109007 |
Object profile sensing
A method for sensing an object profile shape involves relatively sweeping (whisking or translating) in angular or translational increments an elongated whisker element having a deflectable...
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US20120027947 |
Nanotipped device and method
A dispensing device has a cantilever comprising a plurality of thin films arranged relative to one another to define a microchannel in the cantilever and to define at least portions of a dispensing...
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US20120024788 |
DEVICES AND METHODS FOR FILTERING BLOOD PLASMA
The present invention provides systems, devices, kits, and methods for separating blood plasma from whole blood. In particular, the present invention provides systems, devices, and methods for...
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8103076 |
Method for transcatheter intra-arterial perfusion magnetic resonance imaging
A method to serially determine changes in perfusion to tissues is provided. This method involves injecting contrast material into a catheter that is positioned in the blood supply proximal to the...
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US20120016493 |
Passive ankle-foot prosthesis and orthosis capable of automatic adaptation to sloped walking surfaces and method of use
The present invention relates to an improved system for use in rehabilitation and/or physical therapy for the treatment of injury or disease to the lower limbs or extremities. The system can enable...
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US20120015350 |
LATERAL FLOW STRIP AND USES THEREOF
The present invention relates to lateral flow strip assay system and uses thereof. In particular, the present invention relates to lateral flow assay systems for the simple and inexpensive...
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US20120013039 |
Programmable soft lithography: solvent-assisted nanoscle embossing
A method of forming a nanoscale pattern on a substrate is provided, wherein the method increases or decreases the spacing of patterns on the substrate relative to a master, while keeping the...
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8099792 |
Methods and apparatus for spatially resolved photocurrent mapping of operating photovoltaic devices using atomic force photovoltaic microscopy
Atomic force photovoltaic microscopy apparatus and related methodologies, as can be used to quantitatively measure spatial performance variations in functioning photovoltaic devices.
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8099149 |
MRI method for quantification of cerebral perfusion
A method for calculating quantitative perfusion measurements using an MRI system includes a pulse sequence that acquires perfusion weighted images and additionally measures T1 values before and...
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8097877 |
Inorganic-organic hybrid thin-film transistors using inorganic semiconducting films
Inorganic semiconducting compounds, composites and compositions thereof, and related device structures.
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