Patents and Patent Applications from North Carolina State University


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7900625 Inhaler system for targeted maximum drug-aerosol delivery  
A smart inhaler system comprising an inhaler device for directed aerosol delivery facilitated by an adaptive nozzle and a mechanism for inhalation waveform modulation is provided. Methods of using...
PP21744 Sweetpotato plant named ‘NCORNSP-012EMLC’  
‘NCORNSP-012EMLC’ is a new and distinct variety of ornamental sweetpotato having a compact, semi-upright, mounding and spreading habit; produces many short shoots; has foliage that is very...
PP21743 Sweetpotato plant named ‘NCORNSP-011MNLC’  
‘NCORNSP-011MNLC’ is a new and distinct variety of ornamental sweetpotato having a very compact, semi-upright, densely-mounding cultivar producing many, short shoots; the instant variety is...
7897631 Inhibition and dispersion of bacterial biofilms with imidazole-triazole derivatives  
Disclosure is provided for imidazole-triazole derivative compounds such as those given in Formulas (I)-(VI) that prevent, remove and/or inhibit the formation of biofilms, compositions comprising...
7897367 Lactobacillus acidophilus nucleic acid sequences encoding protease homologues and uses therefore  
Protease-like nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, protease-like fusion proteins, antigenic peptides, and...
7888512 Synthesis of nicotine derivatives from nicotine  
Methods of synthesizing nicotine analogs and derivatives are described. In some embodiments the methods utilize an alkyl or aryl silyl-substituted nicotine analog intermediate. Intermediates...
US20110033850 COMPOSITIONS AND METHODS FOR THE IDENTIFICATION OF INHIBITORS OF RETROVIRAL INFECTION  
Methods of identifying inhibitors of retroviral propagation, tRNA used in the methods, and kits, including the tRNA, which can be used in the methods, are disclosed. Methods of treating or...
7884280 Stepwise fabrication of molecular-based, cross linked, light harvesting arrays  
A method of forming a crosslinked, non-discotic backbone polymer coating on a substrate, comprises the steps of: (a) coupling a layer of porphyrinic macrocycles to the substrate; (b) cross-linking...
7884263 Alteration of tobacco alkaloid content through modification of specific cytochrome P450 genes  
Compositions and methods for reducing the level of nornicotine and N′-nitrosonornicotine (NNN) in Nicotiana plants and plant parts thereof are provided. The compositions comprise isolated...
7883772 High strength, durable fabrics produced by fibrillating multilobal fibers  
A fabric including microdenier fibers is provided, the microdenier fibers prepared by fibrillating a multicomponent, multilobal fiber including a contiguous core fiber component enwrapped by a...
7879560 Nanotube structures having a surfactant bilayer inner wall coating  
Nanotubes and nanotube array structures comprise (a) a nanotube having an inner wall portion; and (b) a bilayer coating formed on the inner wall portions, with the bilayer coating comprised of...
US20110020900 LACTOBACILLUS ACIDOPHILUS NUCLEIC ACID SEQUENCES ENCODING PROTEASE HOMOLOGUES AND USES THEREFORE  
Protease-like nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, protease-like fusion proteins, antigenic peptides, and...
US20110020602 CONTROLLED POLARITY GROUP III-NITRIDE FILMS AND METHODS OF PREPARING SUCH FILMS  
The present invention provides methods of preparing Group III-nitride films of controlled polarity and substrates coated with such controlled polarity films. In particular, the invention provides...
7875724 Regiospecific synthesis of nicotine derivatives  
Methods of synthesizing nicotine analogs and derivatives are described. The methods are particularly useful for the regioselective production of enantiomerically pure nicotine analogs having...
US20110015388 Substituted benzazoloporphyrazines for polymerization and surface attachment and articles formed therefrom  
The present invention provides an article of manufacture formed from a substrate and a benzazoloporphyrazine bound to the substrate. The article may take a variety of different forms and may be...
US20110008292 LACTOBACILLUS ACIDOPHILUS NUCLEIC ACIDS ENCODING FRUCTO-OLIGOSACCHARIDE UTILIZATION COMPOUNDS AND USES THEREOF  
Fructooligosaccharide (FOS)-related protein nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, FOS-related fusion...
US20110005499 FUEL INJECTION DEVICE FOR AN INTERNAL COMBUSTION ENGINE, AND ASSOCIATED METHOD  
A fuel injection device and associated method are provided. An injector body defines an axial bore and has a nozzle exit extending into the combustion chamber. The injector body receives fuel...
7868161 Photocrosslinking probes and uses of the same  
A method of detecting a target nucleic acid is disclosed, the method comprising detecting the presence of a fluorescent covalent crosslinked product from non-fluorescent precursors. The...
US20110003954 CYCLOBUTENE POLYMERS AND METHODS OF MAKING THE SAME  
Described is a cyclobutene polymer comprising: monomeric units of cyclobutene, said cyclobutene having at least one fused ring system substituted thereon, said polymer comprising not more than 10...
7863411 Prion protein ligands and methods of use  
Ligands that bind to prion proteins and methods for using the ligands for detecting or removing a prion protein from a sample, such as a biological fluid or an environmental sample. The ligands...
US20100331202 NANOTUBE STRUCTURES HAVING A SURFACTANT BILAYER INNER WALL COATING  
Nanotubes and nanotube array structures comprise (a) a nanotube having an inner wall portion; and (b) a bilayer coating formed on the inner wall portions, with the bilayer coating comprised of...
US20100330284 PROCEDURE FOR PREPARING REDOX-ACTIVE POLYMERS ON SURFACES  
This invention provides novel methods for the formation of redox-active polymers attached to surfaces. In certain embodiments, the methods involve providing redox-active molecules bearing at least...
US20100322859 ORAL DRUG COMPLIANCE MONITORING USING MAGNETIC-FIELD SENSORS  
A method to measure compliance with a pharmaceutical regimen, by the steps of: (a) ingesting a dose of a medication (10) into the gastrointestinal tract of a person, the dose of medication (10)...
PP21561 Clethra alnifolia plant named “Crystalina”  
‘Crystalina’ is a new variety of Clethra alnifolia with a low, compact, rounded habit, with long flower racemes and numerous fragrant flowers, is disclosed.
7838276 Lactobacillus acidophilus nucleic acid sequences encoding carbohydrate utilization-related proteins and uses therefor  
Carbohydrate utilization-related and multidrug transporter nucleic acids and polypeptides, and fragments and variants thereof, are disclosed in the current invention. In addition, carbohydrate...
7829275 Light addressable electrochemical detection of duplex structures  
A method of detecting the presence of an analyte, such as a target nucleic acid sequence, protein sequence or small molecule, which can also be employed to detect the formation of duplex...
US20100279349 NUCLEIC ACIDS ENCODING TWO-COMPONENT SENSING AND REGULATORY PROTEINS, ANTIMICROBIAL PROTEINS AND USES THEREFOR  
Stress-related nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, stress-related fusion proteins, antigenic peptides,...
7826250 Open circuit potential amperometry and voltammetry  
This invention provides approaches to improve the signal to noise ratio (S/N) in electrochemical measurements (e.g., amperometry, voltammetry, etc.). In particular, a method is described wherein...
7824894 Lactobacillus acidophilus nucleic acids encoding fructo-oligosaccharide utilization compounds and uses thereof  
Fructooligosaccharide (FOS)-related protein nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, FOS-related fusion...
US20100274092 FORCE-DETERMINING RETRACTION DEVICE AND ASSOCIATED METHOD  
A retraction device adapted to retract tissue is provided, comprising at least one pair of opposed retraction members, with each retraction member being capable of operably engaging the tissue to...
7820826 Synthesis and regioselective substitution of 6-halo-and 6-alkoxy nicotine derivatives  
The present invention provides active compounds for modulating nicotinic acetylcholine receptors and methods of making the same. The methods of preparing the active compounds utilize different...
7816665 Use of electroactive monolayers in generating negative differential resistance behaviors and devices employing the same  
A negative differential resistance (NDR) device, and methods of making and using the NDR device. The NDR device includes a substrate comprising a conductor material or a semi-conductor material...
7816570 Process for conversion of biomass to fuel  
A process for the direct conversion of lipid biomass fuel stock to combustible fuels include the steps of hydrolyzing a lipid biomass to form free fatty acids, catalytically deoxygenating the free...
7815970 Controlled polarity group III-nitride films and methods of preparing such films  
The present invention provides methods of preparing Group III-nitride films of controlled polarity and substrates coated with such controlled polarity films. In particular, the invention provides...
US20100261983 IMPLANTABLE DEVICES FOR DYNAMIC MONITORING OF PHYSIOLOGICAL AND BIOLOGICAL PROPERTIES OF TUMORS  
Biocompatible sensors configured for implantation include a first body in communication with a plurality of remote sensor bodies to detect physiological parameters in vivo.
US20100255194 GRADIENT FABRICATION TO DIRECT TRANSPORT ON A SURFACE  
The present invention discloses gradients and methods of forming gradients. The gradients can form a component of a molecular machine, such as those disclosed herein. The molecular machines of the...
US20100255036 ATTENUATED FNR DEFICIENT ENTEROBACTERIA  
The invention provides an attenuated enterobacterium comprising an attenuating mutation in the fnr gene, and optionally further comprising a heterologous nucleic acid encoding a foreign antigen....
US20100245489 METHODS AND APPARATUS OF MANUFACTURING MICRO AND NANO-SCALE FEATURES  
The present invention provides methods of generating scalable micro to nano patterned features on a substrate. The methods include ejecting a succession of droplets; applying a force to the...
7803717 Growth and integration of epitaxial gallium nitride films with silicon-based devices  
Epitaxial gallium nitride is grown on a silicon substrate while reducing or suppressing the formation of a buffer layer. The gallium nitride may be grown directly on the silicon substrate, for...
7799910 Geometric synthesis of porphyrin rods  
A method of making a compound of Formula I′ comprises reacting a compound of the formula DLCHO, with a compound of the formula to produce the compound of Formula I′. Methods of using the compounds...
US20100231847 METHODS OF FABRICATING SWITCHABLE LIQUID CRYSTAL POLARIZATION GRATINGS ON REFLECTIVE SUBSTRATES AND RELATED DEVICES  
A method of fabricating a switchable liquid crystal polarization grating includes creating a degenerate planar anchoring condition on a surface of a reflective substrate. An alignment layer may be...
7795509 Tobacco products with reduced nicotine  
DNA encoding a plant quinolate phosphoribosyl transferase (QPRTase) enzyme, and constructs comprising such DNA are provided. Methods of altering quinolate phosphoribosyl transferase expression are...
US20100225876 LOW-TWIST CHIRAL LIQUID CRYSTAL POLARIZATION GRATINGS AND RELATED FABRICATION METHODS  
A polarization grating includes a substrate and a first polarization grating layer on the substrate. The first polarization grating layer includes a molecular structure that is twisted according...
US20100225856 MULTI-LAYER ACHROMATIC LIQUID CRYSTAL POLARIZATION GRATINGS AND RELATED FABRICATION METHODS  
A multi-layer polarization grating includes a first polarization grating layer, a second polarization grating layer on the first polarization grating layer, and a third polarization grating layer...
7790912 Devices containing chiroptical switching materials and methods of making and using the same  
A polycarbodiimide polymer that is reversibly switchable between two distinct optical orientations is described. The polymer is useful in forming devices such as filters, storage media, actuators,...
7787937 Methods, systems, and associated implantable devices for detecting radiation in patients undergoing treatment for cancer  
Methods and systems for evaluating external beam radiation therapy delivered to a subject include: (a) placing at least one wireless implantable sensor in a first subject at a target location; (b)...
US20100209998 CELL-PERMEABILISING PEPTIDES AND POLYPEPTIDES FOR MICROBIAL CELLS  
Signal peptides and polypeptides from Methanobrevibacter ruminantium, a methanogenic archaea present in ruminants. Methods of using these peptides to permeabilise microbial cells, particularly M....
7778692 Methods, systems, and associated implantable devices for detecting radiation in patients undergoing treatment for cancer  
Methods and systems for evaluating external beam radiation therapy delivered to a subject include: (a) placing at least one wireless implantable sensor in a first subject at a target location; (b)...
7775974 Force-determining retraction device and associated method  
A retraction device including at least one pair of opposed retraction members, with each retraction member being capable of operably engaging the tissue to be retracted. A drive mechanism is...
US20100205703 Cercis plant named 'Ruby Falls'  
Cercis ‘Ruby Falls’ is a new and distinct variety of redbud that has the following unique combination of desirable features that are outstanding in a new variety. 1. Weeping growth habit.2. Ease...