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Patents and Patent Applications from New York University


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US20140283217 Methods of Affecting Plant Growth With MicroRNA  
Provided herein are compositions and methods for producing transgenic plants. In specific embodiments, transgenic plants comprise a construct comprising a polynucleotide encoding microRNA167...
US20140273209 ARTIFICIAL IMMUNE SYSTEM: METHODS OF USE  
The present invention relates to methods of constructing an integrated artificial immune system that comprises appropriate in vitro cellular and tissue constructs or their equivalents to mimic the...
US20140273003 SUPER-RESOLUTION FLUORESCENCE LOCALIZATION MICROSCOPY  
The present invention relates generally ultrasensitive assays for use in diagnostics and in methods of drug screening and personalizing therapy for an individual patient. Specifically, the present...
8835835 Biomarkers of ionizing radiation  
The present invention provides novel radiation associated markers. The radiation associated markers may be one or more of albumin, LTGF-β, or any protein or peptide listed in any one of Tables 1, ...
8835619 Heat shock proteins from Mycobacterium leprae and uses thereof  
The present invention is directed to heat shock proteins from Mycobacterium leprae as well as their encoding polynucleotides and vectors and host cells containing these polynucleotides. These heat...
8835123 Methods for detecting progenitor cells and uses thereof  
Diagnostic and therapeutic methods pertaining to diseases and disorders of the breast, uterus and ovary are encompassed herein. More particularly, diagnostic methods for early detection of...
8833368 System and method for circuits to allow CPAP to provide zero pressure  
A system comprises a respiratory delivery arrangement adapted to cover at least one respiratory orifice of a patient. The system also comprises a first conduit having a first end and a second end,...
US20140256594 DNA PHOTOLITHOGRAPHY WITH CINNAMATE CROSSLINKERS  
The present invention relates generally to cinnamate crosslinkers. Specifically, the present invention relates to gels, biochips, and functionalized surfaces useful as probes, in assays, in gels,...
8828413 Peptoid oligomers, pharmaceutical compositions and methods of using the same  
Novel peptoid oligomers are disclosed that have a formula represented by the following formula I: The peptoids demonstrate antimicrobial activity and may be prepared as pharmaceutical compositions...
US20140244035 Manipulation of Objects  
A system for manipulation of objects. The system includes N objects, where N is greater than or equal to 2 and is an integer; and a mechanism for controlling and 2D locating of the N objects. A...
US20140243531 SUPERSTRUCTURES OF DIKETOPYRROLOPYRROLE DONORS AND PERYLENEDIIMIDE ACCEPTORS FORMED BY HYDROGEN-BONDING AND PI...PI STACKING  
A quantitative model that describes the assembly of diketopyrrolopyrrole-based donors and a perylenediimide acceptor into chiral superstructures, as a result of both hydrogen bonding and...
US20140243260 CHIMERIC FIBROBLAST GROWTH FACTOR 23 PROTEINS AND METHODS OF USE  
The present invention relates to an isolated chimeric protein. The isolated chimeric protein includes an N-terminus coupled to a C-terminus, where the N-terminus includes an N-terminal portion from...
8815327 Graded glass/zirconia/glass structures for damage resistant ceramic dental and orthopedic prostheses  
The present invention provides a functionally graded glass/ceramic/glass sandwich system for use in damage resistant, ceramic and orthopedic prosthesis. The functionally graded...
8815118 Lock and key colloids and methods of manufacture  
A method and system for assembling building blocks of colloidal particles and also for shaping of colloids for self-assembly for manufacturing, processing and formation of compositions of matter. A...
US20140233306 BIPOLAR SPIN-TRANSFER SWITCHING  
A magnetic device includes a magnetized polarizing layer, a free magnetic layer, and a reference layer. The free magnetic layer forms a first electrode and is separated from the magnetized...
8811706 System, method and computer accessible medium for providing real-time diffusional kurtosis imaging and for facilitating estimation of tensors and tensor-derived measures in diffusional kurtosis imaging  
Exemplary method, system, and computer-accessible medium can be provided for determining a measure of diffusional kurtosis by receiving data relating to at least one diffusion weighted image, and...
US20140229164 APPARATUS, METHOD AND COMPUTER-ACCESSIBLE MEDIUM FOR EXPLAINING CLASSIFICATIONS OF DOCUMENTS  
Classification of collections of items such as words, which are called “document classification,” and more specifically explaining a classification of a document, such as a web-page or website. Thi...
8806456 Configuration-preserving preprocessor and configuration-preserving parser  
Methods, systems, and apparatuses, including computer programs encoded on computer readable media, for generating a plurality of tokens from one or more source files that include source code in a...
8802722 Benzopyran compounds as melanogenesis modifiers and uses thereof  
Provided are benzopyran compounds of formula I, for example, pomiferin-3′,4′-dimethyl ether, and the use of such compounds and compositions thereof to modulate (e.g., inhibit) melanogenesis and pig...
8802660 De novo synthesis of glucocorticoids in the epidermis and its uses and applications  
The present invention relates to methods and compositions that control, i.e., antagonize/inhibit or agonize/stimulate, de novo glucocorticoid production in the skin. Such methods and compositions...
US20140221229 GENOMIC SIGNATURES OF METASTASIS IN PROSTATE CANCER  
A method of determining the risk of metastasis of prostate cancer in a human subject who has or had prostate cancer is disclosed herein. The method is based on detecting in a prostate sample from...
US20140220159 HYDROGEN-BOND SURROGATE PEPTIDES AND PEPTIDOMIMETICS FOR p53 REACTIVATION  
The present invention relates to peptidomimetics for reactivating p53. Methods of using the peptidomimetics are also disclosed.
US20140220036 METHODS FOR TREATING NEURODEGENERATIVE DISEASES AND FOR IDENTIFYING AGENTS USEFUL FOR TREATING NEURODEGENERATIVE DISEASES  
The present invention provides methods of inhibiting a tau protein such as h-tau42 or a biologically active fragment, derivative or analog thereof, methods of treating a disease caused by a tau...
8796449 s-Triazine compounds, pharmaceutical compositions and methods of using the same  
Novel s-triazine compounds are disclosed that have a formula represented by the following: L1, L2, L3, R1, R2, R3, R4, R5a, R5b, and R5c are as described herein. The compounds may be prepared as...
US20140212456 TREATMENT METHODS USING ATOXIC NEUROTOXIN DERIVATIVES  
The present invention relates to a treatment method. This method involves contacting a subject with an isolated, physiologically active, atoxic derivative of a Clostridial neurotoxin. Contacting is...
US20140212413 Methods of Treating TNF-alpha-Mediated Diseases Using Chimeric TNF-alpha Antibodies  
Anti-TNF antibodies, fragments and regions thereof which are specific for human tumor necrosis factor-α (TNFα) and are useful in vivo diagnosis and therapy of a number of TNFα-mediated pa...
8791985 Tracking and characterizing particles with holographic video microscopy  
In-line holography to create images of a specimen, such as one or more particles dispersed in a transparent medium. Analyzing these images with results from light scattering theory yields the...
8791121 Oligooxopiperazines and methods of making and using them  
The present invention relates to oligooxopiperazines and their use. Methods for preparing oligooxopiperazines are also disclosed.
US20140206718 Method of enhancing lysosomal alpha-Galactosidase A  
A method of enhancing the activity of lysosomal α-Galactosidase A (α-Gal A) in mammalian cells and for treatment of Fabry disease by administration of 1-deoxy-galactonojirimycin and related compounds.
US20140205681 HYDROGEN-BOND SURROGATE PEPTIDES AND PEPTIDOMIMETICS FOR p53 REACTIVATION  
The present invention relates to peptidomimetics for reactivating p53. Methods of using the peptidomimetics are also disclosed.
US20140205655 OLIGOOXOPIPERAZINES FOR p53 REACTIVATION  
The present invention relates to oligooxopiperazines for reactivating p53. Methods of using the oligooxopiperazines are also disclosed.
US20140205609 METHODS FOR INDUCING SYSTEMIC IMMUNE RESPONSES TO CANCER  
Pharmaceutical compositions comprising molecules produced by antigen-stimulated peripheral blood mononuclear cells (PBMCs) that induce systemic immune responses to cancers are encompassed herein,...
US20140205153 SYSTEMS, METHODS AND COMPUTER-ACCESSIBLE MEDIUMS FOR AUTHENTICATION AND VERIFICATION OF PHYSICAL OBJECTS  
Exemplary methodology, procedure, system, method and computer-accessible medium can be provided for authenticating a non-digital medium of a physical object, by receiving at least one image of...
8781153 Method, system, and computer-accessible medium for authentication of paper using a speckle pattern  
An exemplary methodology, procedure, system, method and computer-accessible medium can be provided for authenticating a portion of a non-digital medium for a document, by receiving at least one...
8780616 Magnetic memory system and methods in various modes of operation  
A magnetic memory system includes a superconductor circuit and one or more magnetic memory elements to store data. To write data, a driver circuit in the superconductor circuit generates a magnetic...
8778905 USP47 inhibitors and methods to induce apoptosis  
The present invention relates to USP47 (ubiquitin specific protease 47) inhibitors and methods for inducing apoptosis or cell death in a target cell. In certain embodiments, the invention relates...
US20140191439 Continuous Feed 3D Manufacturing  
Disclosed herein is a method and apparatus adapted for the free-form manufacture of complex systems using multiple three-dimensional (3D) printing techniques using multiple materials on a...
8772267 Treatment of spinal mechanical pain  
The invention is directed to a method of treating chronic spinal mechanical pain by intravenous administration to a subject in need of chronic spinal mechanical pain relief of an effective amount...
8772252 Coumarin compounds as melanogenesis modifiers and uses thereof  
Provided are coumarin compounds of formula I, for example, robustic acid methyl ether, and the use of such compounds and compositions thereof to modulate (e.g., inhibit) melanogenesis and...
8771652 Methods of blocking ultraviolet radiation and promoting skin growth using terpenes and terpenoids  
The present invention provides methods of treating humans and animals with terpenes and terpenoids in order to rejuvenate the skin and increase the protective layer against irradiation by...
8766925 Method and apparatus for providing input to a processor, and a sensor pad  
An apparatus for providing input to a processor includes a sensor pad having a surface and a sensor array for sensing pressure at the surface and producing signals corresponding to the pressure at...
8766169 Sorting colloidal particles into multiple channels with optical forces: prismatic optical fractionation  
A method and system for controlled fractionation of particles. A sample having a plurality of particles of different size distributions. A uniform array for the preparing of optical traps having a...
8762319 Method, system, and computer-accessible medium for inferring and/or determining causation in time course data with temporal logic  
Time-course data with an underlying causal structure may appear in a variety of domains, including, e.g., neural spike trains, stock price movements, and gene expression levels. Provided and...
8760915 High speed low power magnetic devices based on current induced spin-momentum transfer  
A high speed, low power method to control and switch the magnetization direction and/or helicity of a magnetic region in a magnetic device for memory cells using spin polarized electrical current....
US20140170685 BIOMARKER OF ASBESTOS EXPOSURE AND MESOTHELIOMA  
Several embodiments provided herein relate to methods of diagnosing asbestos exposure or mesothelioma. Several embodiments also relate to methods of differentiating whether a tumor of the lung is...
US20140170647 Compositions and Methods for Analyzing Immobilized Nucleic Acids  
The present invention provides methods of detecting a nucleic acid analyte in a sample. The methods generally involve modifying immobilized nucleic acids from a sample onto an insoluble support in...
US20140170163 MONOCLONAL ANTIBODIES AGAINST INFLUENZA VIRUS GENERATED BY CYCLICAL ADMINISTRATION AND USES THEREOF  
Provided herein are methods of producing neutralizing monoclonal antibodies, by cyclical immunization, that cross-react with strains of Influenza virus of the same subtype or different subtypes....
8756468 Architecture, system, method, and computer-accessible medium for toggle-based masking  
Exemplary embodiments of the present disclosure include apparatus, methods, and computer-accessible medium for a toggle-masking procedure configured to mask, e.g., most or all the unknown x's and...
8755222 Bipolar spin-transfer switching  
Orthogonal spin-transfer magnetic random access memory (OST-MRAM) uses a spin-polarizing layer magnetized perpendicularly to the free layer to achieve large spin-transfer torques and ultra-fast...
8753830 Methods to identify compounds useful for tumor sensitization to DNA damage  
Cdc25A is herein identified as a substrate for β-TrCP1- or β-TrCP2-mediated ubiquitination and subsequent degradation via the ubiquitin-proteasome pathway. In particular, it has been found that i...