Patents and Patent Applications from New York University


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US20190343923 THERAPEUTIC AND COSMETIC USES AND APPLICATIONS OF CALRETICULIN  
The invention relates to therapeutic and cosmetic uses of calreticulin including reducing eliminating wrinkles and/or fine lines, tissue repair and reconstruction, repairing damaged and/or...
US20190342731 SYSTEM METHOD AND COMPUTER-ACCESSIBLE MEDIUM FOR BLOCKCHAIN-BASED DISTRIBUTED LEDGER FOR ANALYZING AND TRACKING ENVIRONMENTAL TARGETS  
An exemplary multi-robot system can include, for example, a first robot(s), which can include a communication arrangement and a sensor arrangement configured to detect a presence of an object(s)...
US20190340394 SYSTEM, METHOD AND COMPUTER-ACCESSIBLE MEDIUM FOR SATISFIABILITY ATTACK RESISTANT LOGIC LOCKING  
Exemplary embodiment of the present disclosure can include, for example, a logic-locking circuit (“SARLock”), which can include a logic cone(s) receiving a distinguishing input pattern(s) (DIP), a...
US20190340392 ANOMALY DETECTION IN REAL-TIME MULTI-THREADED PROCESSES ON EMBEDDED SYSTEMS AND DEVICES USING HARDWARE PERFORMANCE COUNTERS AND/OR STACK TRACES  
An aspect of behavior of an embedded system may be determined by (a) determining a baseline behavior of the embedded system from a sequence of patterns in real-time digital measurements extracted...
US20190339455 CLOSED LOOP MICRORESONATORS HAVING LINEAR PORTIONS AND FILLETED CORNERS, SYSTEMS INCLUDING SUCH MICRORESONATORS, AND METHODS OF FABRICATING SUCH MICRORESONATORS  
The use of microresonators with sharp corners (rectangular and square-shaped) can be limited by severe energy loss at the corners. The effect of incorporating fillet design at sharp corners...
US20190338004 IMMUNOTHERAPEUTIC MODULATION OF AMYLOIDOGENIC DISEASE USING NON-FIBRILLOGENIC, NON-AMYLOIDOGENIC POLYMERIZED PROTEINS AND PEPTIDES  
The present invention is directed to polymerized products and compositions useful for the treatment and prevention of amyloid disease in a subject. The invention further relates to isolated...
10464979 FGF23 c-tail fusion proteins  
Disclosed herein are FGF23 c-tail fusion proteins, pharmaceutical compositions comprising the FGF23 c-tail fusion proteins, and methods of treatment using the FGF23 c-tail fusion proteins. This...
10463752 Protein polymer gold nanoparticle hybrid materials for small molecule delivery  
Protein polymer-gold nanoparticles, compositions comprising protein polymer-gold nanoparticles, and uses of protein polymer-gold nanoparticles. A protein polymer-gold nanoparticle comprises a gold...
US20190332207 Sensor Having a Set of Plates, and Method  
A sensor having a set of plates that are in contact from their bottom at the corners with a set of protrusions that are in contact from above with a plurality of intersections, each having a...
US20190330284 STAPHYLOCOCCUS AUREUS LEUKOCIDINS, THERAPEUTIC COMPOSITIONS, AND USES THEREOF  
Disclosed herein are isolated and purified Staphylococcus aureus bi-component leukocidin, referred to herein as LukAB, and its components LukA and LukB, antibodies specific to LukA, antibodies...
US20190328764 PREVENTING AND TREATING AMYLOID- BETA DEPOSITION BY STIMULATION OF INNATE IMMUNITY  
The present invention is directed to a method of preventing or reducing amyloid deposition in a subject. This method involves selecting a subject with amyloid deposits and stimulating the innate...
10456432 Oncolytic herpes simplex virus and therapeutic uses thereof  
The present invention relates to variants of herpes simplex virus (HSV) that selectively infect and replicate in cancer cells, including HSV strains that selectively infect and replicate in...
US20190326019 METHODS, COMPUTER-ACCESSIBLE MEDIUM AND SYSTEMS TO MODEL DISEASE PROGRESSION USING BIOMEDICAL DATA FROM MULTIPLE PATIENTS  
An exemplary embodiment of system, method and computer-accessible medium can be provided to reconstruct models based on the probabilistic notion of causation, which can differ fundamentally from...
10450374 Anti-galectin-9 antibodies and uses thereof  
Disclosed herein are anti-Galectin-9 antibodies and methods of using such for inhibiting a signaling pathway mediated by Galectin-9 or eliminating pathologic cells expressing Galectin-9. Such...
10449229 Compositions and methods for cartilage defect repair using a RHAMM-mimetic peptide  
Provided are methods and compositions for cartilage repair. The method involves performing a surgical procedure at the site of a cartilage defect and administering a composition comprising a...
US20190315841 Antibody-Based Molecules Specific for the Truncated ASP421 Epitope of Tau and Their Uses in the Diagnosis and Treatment of Tauopathy  
The present invention relates to antibody-based molecules (including single domain antibody fragment, scFv molecules, antibodies, antibody fragments, diabodies, and the epitope-binding domains...
10443043 Methods for making induced pluripotent stem cells  
In vitro methods for generating induced pluripotent cells (iPSCs) are disclosed herein. Also encompassed are recombinant iPSCs generated using these methods and methods of use thereof.
10441541 Methods and compositions for treating osteoarthritis and promoting cartilage formation  
The invention provides methods and compositions for treating or inhibiting the development of osteoarthritis in a subject having osteoarthritis or at risk for developing osteoarthritis and for...
10441428 Early intervention knee implant device and methods  
A replacement knee implant has a femoral implant and a tibial implant, each of which are inset in a bone surface. The tibial implant is generally elongated with one end rounded and an opposite end...
US20190311509 GENERATION AND PRESENTATION OF DISTANCE CARTOGRAMS  
Technology for generating and presenting distance cartograms, which use region partitioning for scalable construction of time space, is disclosed. A representative method includes obtaining a...
US20190310211 SYSTEM AND METHOD FOR MAGNETIC RESONANCE MAPPING OF PHYSICAL AND CHEMICAL CHANGES IN CONDUCTING STRUCTURES  
A method of diagnosing a conducting structure includes providing the conducting structure in a magnetic field, immersing the conducting structure in a detection medium, or placing a detection...
US20190309314 YEAST SYNTHETIC BIOLOGY PLATFORM FOR IDENTIFYING SHIKIMATE PATHWAY ENZYME INHIBITORS  
Provided are compositions and methods for compound discovery. Modified yeast that have their endogenous yeast shikimate pathway disrupted or deleted, and replaced with homologous pathway genes...
10438560 Reducing visual crowding, increasing attention and improving visual span  
Methods, systems, and apparatuses, including computer programs encoded on computer readable media, for modifying displayed text in a gaze-contingent way to reduce crowding, thus increasing the...
US20190300910 SCRaMbLE OF HETEROZYGOUS DIPLOID YEAST  
Provided are compositions and methods for making a diploid yeast having heterozygosity for at least one chromosome. The method includes mating haploid yeast having at least a first modified...
US20190300909 EXTRACHROMOSOMAL SWITCHING AUXOTROPHIES PROGRESSIVELY BY INTEGRATION (ESWAP-IN) FOR ASSEMBLY OF DNA SEQUENCES IN YEAST  
Compositions, methods and kits are provided. The compositions, methods and kits are for assembly of series of DNA segments in yeast using homologous recombination. The assembled DNA segments are...
10433408 Methods for affecting spinning atmospheric phenomena  
A system and method for misbalancing or suppressing spinning atmospheric phenomena such as tornadoes, landspouts, waterspouts, gustnadoes and whirlwinds. The systems and methods misbalance or...
US20190290688 METHODS AND REAGENTS FOR MODULATING MACROPHAGE PHENOTYPE  
The present invention is directed to methods of inducing a phenotypic change in a population of monocytes and/or macrophages. The method includes administering to the population of monocytes...
10423749 System, method and computer-accessible medium for providing secure split manufacturing  
Exemplary systems, methods and computer-accessible mediums can secure split manufacturing of an integrated circuit by modifying a previous location of at least one pin to a further location of the...
10421954 Hybrid polymers, pharmaceutical compositions and methods of synthesizing the same  
Novel hybrid polymers are disclosed that have a structure represented by the following formula I: wherein Abiotic oligomer, Polypeptide, X, Y, and R1 are as described herein. The methods to...
US20190282674 USE OF HYALURONIDASE FOR TREATMENT OF MUSCLE STIFFNESS  
Provided are methods and kits for reducing the severity of muscle stiffness. The method comprises delivering to one or more specific locations in the deep fascia of an affected muscle a...
10419191 Systems, methods, and computer-readable media utilizing an improved radio frame design and MAC layer for ultra-low latency  
Exemplary communication apparatus comprising a MAC-layer processor configured to receive data for a downlink transmission to a first device; transmit a grant comprising resource allocations for...
10416756 Foot operated navigation and interaction for virtual reality experiences  
An apparatus for creating movement in a virtual reality for a user includes a computer includes a virtual reality headset in communication with the computer that is worn on the head of the user so...
10413414 Replica guided motion knee  
A total knee replacement, comprising a femoral and a tibial component in articulating contact that can restore normal joint function. The articulation between the two components is controlled by...
US20190280791 SYSTEM, METHOD AND COMPUTER-ACCESSIBLE MEDIUM FOR SIMULATION AND EMULATION OF WIRELESS CLUSTER AND/OR TAPPED DELAY LINE MODELS  
An exemplary device for emulating a wireless channel(s) can be provided, which can include, for example, a first communication interface configured to receive a first data signal(s) from a...
US20190275744 SYSTEM AND METHOD FOR MALWARE DETECTION IN ADDITIVE MANUFACTURED PARTS  
A system for detecting corruption in a three-dimensional model for use in additive manufacturing comprises a non-transitory computer-readable medium with instructions stored thereon, that when...
US20190275274 MULTI-NIGHT TITRATION PRESSURE DETERMINATION  
A multi-night titration (MNT) process to find an optimal single therapeutic pressure of a CPAP device. This single therapeutic pressure can then be used on an on-going basis by the patient after...
US20190271677 METHODS AND KITS FOR DETECTING NON-LUMINESCENT OR WEAKLY LUMINESCENT METALS  
The invention provides methods and kits for detecting the presence of, the amount of, or the concentration of a substantially non-emitting metal in a sample by a) providing a sensitizer to a...
US20190265950 SYSTEM, METHOD, AND APPARATUS FOR RECURRENT NEURAL NETWORKS  
A method for computation with recurrent neural networks includes receiving an input drive and a recurrent drive, producing at least one modulatory response; computing at least one output response,...
US20190264636 DIRECTIONALLY TARGETED JET NOISE REDUCTION SYSTEM AND METHOD  
An exemplary engine noise reduction system, can be provided, which can include a noise reduction fluid source, and a microjet(s) placed at an axial location downstream from a nozzle exit of an...
10397044 Network function virtualization (“NFV”) based communications network resilience  
The problem of recovering from multiple link failures in a way that is quick, avoids loops, avoids packet modifications, and that avoids significant modifications to existing routers is solved by:...
US20190256612 SPECIFIC MURINE AND HUMANIZED MONOCLONAL ANTIBODIES DETECTING PATHOLOGY ASSOCIATED SECONDARY STRUCTURE CHANGES IN PROTEINS AND PEPTIDES  
The present invention relates to antibodies and binding fragments thereof that bind the β-sheet secondary structure of a pathological monomeric or oligomeric non-fibrillar proteins without binding...
US20190256604 ANTI-GALECTIN-9 ANTIBODIES AND USES THEREOF  
Disclosed herein are anti-Galectin-9 antibodies and methods of using such for inhibiting a signaling pathway mediated by Galectin-9 or eliminating pathologic cells expressing Galectin-9. Such...
10384024 System and method for diagnosis and treatment of a breathing pattern of a patient  
Described is a system including a sensor and a processing arrangement. The sensor measures data corresponding to a patient's breathing patterns. The processing arrangement analyzes the breathing...
10383887 Preventing and treating amyloid-beta deposition by stimulation of innate immunity  
The present invention is directed to a method of preventing or reducing amyloid deposition in a subject. This method involves selecting a subject with amyloid deposits and stimulating the innate...
US20190248876 CELLULAR FACTORS INVOLVED IN THE CYTOTOXICITY OF STAPHYLOCOCCUS AUREUS LEUKOCIDINS: NOVEL THERAPEUTIC TARGETS  
The present invention relates to methods for treating and preventing Staphylococcus aureus infection and/or a condition resulting from a S. aureus infection in a subject that involves...
10381950 Resonant inverter topology, wireless charger, and control method  
A wireless charger for an electric vehicle and a resonant inverter comprising a resonant portion that serially connects to a phase shifting portion and serially connects with a load component and...
10381155 Winding for low-voltage coils of distribution-class toroidal transformers  
A novel winding method is described herein which eliminates the circulating currents for wound transformers. A first layer of a wire is wound about the core at a first set of angles. Next, a loop...
10376603 Engineered fluorinated biomaterials  
Provided are protein polymers providing the dual functionality of delivery and imaging. The protein polymers comprise a coiled-coil domain of the cartilage oligomeric matrix protein and repeats of...
US20190239992 METHOD AND DEVICES TO INCREASE CRANIOFACIAL BONE DENSITY  
The present invention relates to a method for increasing bone growth in teeth and/or other craniofacial regions of a subject. This method includes administering to the jaw and/or teeth of the...
10370694 Size dependence of nanoparticle-protein interaction and high sensitivity potentiometric sensor exploiting such interactions  
Fabrication of a high sensitivity potentiometric biosensor is described. The present inventors have developed and characterized a novel amplification platform using a gold nanoparticle (GNPs)...