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Patents and Patent Applications from New York University


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US20140107979 PRECISE FERQUENCY-PATTERN ANALYSIS TO DECOMPOSE COMPLEX SYSTEMS INTO FUNCTIONALLY INVARIANT ENTITIES  
Methods, systems, and apparatuses, including computer programs encoded on computer readable media, for registering a multichannel time series from data collected from a plurality of channels. Each...
US20140107022 CHIMERIC FIBROBLAST GROWTH FACTOR 19 PROTEINS AND METHODS OF USE  
The present invention relates to a chimeric protein that includes an N-terminus coupled to a C-terminus, where the N-terminus includes a portion of a paracrine fibroblast growth factor (“FGF”) and...
US20140103473 INCREASED MAGNETORESISTANCE IN AN INVERTED ORTHOGONAL SPIN TRANSFER LAYER STACK  
A magnetic device includes a pinned magnetic layer and a free magnetic layer including a first body-centered cubic material and having a variable magnetization vector that has a first stable state...
US20140103472 INVERTED ORTHOGONAL SPIN TRANSFER LAYER STACK  
A magnetic device includes a pinned magnetic layer having a first fixed magnetization vector with a first fixed magnetization direction. The magnetic device also includes a free magnetic layer...
8700142 Brain function scan system  
A portable EEG (electroencephalograph) instrument, especially for use in emergencies and brain assessments in physicians' offices, detects and amplifies brain waves and converts then into digital...
US20140100354 PEPTOID COMPOSITIONS AND METHODS OF USING THE SAME  
Novel peptoids are disclosed that have a formula represented by the following formulae Ia and Ib: wherein X, Y, R, and n are as described herein. The peptoids demonstrate catalytic activity and are...
US20140094457 PHARMACEUTICAL COMPOSITIONS AND TREATMENT OF GENETIC DISEASES ASSOCIATED WITH NONSENSE MEDIATED RNA DECAY  
The present invention relates to pharmaceutical compositions comprising a compound and a pharmaceutically acceptable carrier. The present invention is also directed to a method of treating a...
US20140094406 CHIMERIC FIBROBLAST GROWTH FACTOR 21 PROTEINS AND METHODS OF USE  
The present invention relates to a chimeric protein that includes an N-terminus coupled to a C-terminus, where the N-terminus includes a portion of a paracrine fibroblast growth factor (“FGF”) and...
US20140094382 METHODS AND AGENTS FOR MODULATING PROTOCADHERIN-18 ACTIVITY  
Screening assays and methods of using same for screening to identify modulator agents or compounds that affect pcdh18 mediated inhibition of T cell effector function are described herein....
8685718 Mucosal immunization to prevent prion infection  
Vaccines against prion disease eliciting a humoral immune response when administered mucosally are described. The vaccines comprise a prion protein, a prion protein fragment, or a non-amyloidogenic...
US20140089144 APPARATUS, SYSTEM, METHOD AND COMPUTER-ACCESSIBLE MEDIUM FOR PERFORMING A PRODUCT SEARCH USING USER-GENERATED AND CROWD-SOURCED CONTENT  
A non-transitory computer-readable medium, method and system for providing results associated with a ranking of a plurality of items of a particular item type can be provided. For example, for each...
US20140086826 SIN3B COMPLEX INHIBITION FOR PREVENTING HEMATOLOGIC CHEMOTHERAPY- AND RADIOTHERAPY-INDUCED CYTOTOXICITY  
Methods for inactivating Sin3B and its associated activities to prevent, inhibit or attenuate hematopoietic stem cell exhaustion and chemotherapy- and radiotherapy-induced hematologic cytotoxicity...
8680070 Medical implants containing adenosine receptor agonists and methods for inhibitiing medical implant loosening  
The invention provides methods and compositions for reducing or inhibiting bone resorption, osteoclast differentiation and stimulation and the loosening of medical prostheses by administering a...
US20140080899 miR-33 Inhibitors and Uses Thereof to Decrease Inflammation  
The inhibition of miRNA miR-33 is shown to promote the polarization of macrophages from an M1 to an M2 phenotype. MiR-33 inhibitors are therefore useful for treating inflammation in subjects....
US20140080824 STRUCTURE-GUIDED IDENTIFICATION OF BINDING INTERACTIONS OF HUMAN LAMININ RECEPTOR PRECURSOR WITH LAMININ AND IDENTIFICATION OF COMPOUNDS THAT AFFECT BINDING  
The present invention pertains to compounds which interfere with the binding of laminin to the laminin receptor (LamR). Such compounds are useful for treating diseases such as cancer, Alzheimer's...
8674695 Radio frequency coil arrangement for high field magnetic resonance imaging with optimized transmit and receive efficiency for a specified region of interest, and related system and method  
For example, the present disclosure provides exemplary embodiments of a coil arrangement that can include, e.g., a plurality of elements which can be provided at an angle from one another. The...
8673859 GM-CSF cosmeceutical compositions and methods of use thereof  
It has been discovered that granulocyte macrophage colony stimulating factor (“GM-CSF”) promotes migration of activated (but not differentiating) keratinocytes to wound sites. It was also dis...
8673314 Monoclonal antibodies against influenza virus generated by cyclical administration and uses thereof  
Provided herein are methods of producing neutralizing monoclonal antibodies, by cyclical immunization, that cross-react with strains of Influenza virus of the same subtype or different subtypes....
US20140067079 IMPLANTS FOR THE TREATMENT OF OSTEOARTHRITIS OF THE KNEE  
A replacement knee implant has a femoral implant and a tibial implant, each of which are inset in a bone surface. The tibial implant is generally elongated with one end rounded and an opposite end...
US20140066951 COCHLEAR IMPLANT WITH IMPROVED ELECTRODE ARRAY AND CONTROLLER  
A cochlear implant device includes a deformable and stretchable flexible strip composed of a biological compatible material and positioned about a longitudinal axis so as to form a spiral. The...
US20140066461 METHODS FOR DIAGNOSING AND TREATING SCHIZOPHRENIA  
Genetic markers of schizophrenia (SCZ) are presented herein, as are methods for using same for assessing risk of developing SCZ and diagnosing SCZ. Methods for choosing a therapeutic regimen and...
US20140066362 METHOD FOR TREATING INFECTIONS BY TARGETING MICROBIAL H2S-PRODUCING ENZYMES  
The invention provides materials and methods for treating infections by reducing endogenous microbial H2S levels.
US20140057961 SIN3B COMPLEX INHIBITION AND USE THEREOF IN THE PREVENTION OF PRO-ONCOGENIC INFLAMMATION AND CANCER  
Methods for inactivating Sin3B and its associated activities to prevent, inhibit or attenuate pro-oncogenic inflammation and cancer progression, in particular pancreatic cancer progression are...
US20140057905 CANCER DIAGNOSTICS, THERAPEUTICS, AND DRUG DISCOVERY ASSOCIATED WITH MACROPINOCYTOSIS  
The present invention is directed to methods of inhibiting both proliferation and survival of cancer cells and for treating a subject having cancer. The present invention is further directed to...
8658677 Pyridyl-2-methylamino compounds, compositions and uses thereof  
Compounds are provided according to formula I: where R, R′, R3, R4, R5, and R6 are as defined herein. Provided compounds and pharmaceutical compositions thereof are useful for the prevention and t...
US20140052686 METHOD, SYSTEM AND SOFTWARE ARRANGEMENT FOR RECONSTRUCTING FORMAL DESCRIPTIVE MODELS OF PROCESSES FROM FUNCTIONAL/MODAL DATA USING SUITABLE ONTOLOGY  
A method, system and software arrangement in accordance with an exemplary embodiment of the present invention are provided to extract descriptive narrative from numerical experimental data...
US20140050803 COMPOSITIONS AND METHODS FOR TREATMENT OF MELANOMA  
Described herein are compositions and methods for the prognosis, prevention and treatment of melanoma or melanoma associated symptoms. The compositions are microRNA molecules associated with...
US20140046452 TOTAL KNEE REPLACEMENT SUBSTITUTING FUNCTION OF ANTERIOR CRUCIATE LIGAMENT  
A total knee replacement prosthesis comprising condylar and intercondylar bearing surfaces configured to manage anterior/posterior displacement between the articulating femoral and tibial components.
US20140045860 SMALL MOLECULE INHIBITORS FOR TREATING PARASITIC INFECTIONS  
The invention relates to a compound of Formula I or a pharmaceutically acceptable ester, salt, prodrug or metabolite thereof;
US20140045769 HYDROGEN BOND SURROGATE MACROCYCLES AS MODULATORS OF RAS  
The present invention relates to peptides having one or more stable, internally-constrained HBS α-helices, where the peptide is capable of interacting with Ras and related proteins.
US20140045756 METHODS AND COMPOSITIONS FOR MODULATING TNF/TNFR SIGNALING  
The present disclosure relates to methods and compositions for modulating TNF and TNFR signaling. In particular, the disclosure describes methods and compositions for inhibiting TNFα signaling, ...
8647329 System and method for correction of intracerebral chemical imbalances  
An osmotic pump includes a plurality of agent reservoirs; first and second solute chambers; a semi-permeable membrane separating the first and second solute chambers from one another; a flexible...
US20140037629 HUMANIZED SINGLE-CHAIN ANTIBODY AGAINST BETA 3 INTEGRIN FOR THE TREATMENT AND PREVENTION OF METASTASIS  
The present invention relates to methods inhibiting tumor metastasis and treating cancer in a subject that involve administering to the subject an antibody which recognizes GPIIIa49-66, under...
US20140030216 METHODS, AGENTS AND PEPTIDES FOR INDUCING AN IMMUNE RESPONSE TO MATRIX METALLOPROTEINASE-2 EXPRESSING TUMORS  
The present invention relates to enhancing, modulating or stimulating the immune response to MMP-2 expressing tumors, including melanoma, and to the modulation and application of immune modulators...
US20140025716 COMPUTATIONS USING A POLYCHRONOUS WAVE PROPAGATION SYSTEM  
The present invention relates to a polychronous wave propagation system that is based on relative timing between two or more propagated waves through a wave propagation medium. The relative timing...
8633221 Method of enhancing lysosomal α-galactosidase A  
A method of enhancing the activity of lysosomal α-Galactosidase A (α-Gal A) in mammalian cells and for treatment of Fabry disease by administration of 1-deoxy-galactonojirimycin and related compounds.
US20140018936 INCREASING SURVIVAL OF FREE TISSUE GRAFTS AND FLAPS USING PHOSPHODIESTERASE TYPE 5 (PDE5) INHIBITORS  
The present invention relates to methods of tissue grafting and microvascular free flap transfer that involve administering a phosphodiesterase type-5 inhibitor to the tissue graft or microvascular...
8629729 Aggregated spin-torque nano-oscillators  
A nano-oscillator magnetic wave propagation system has a group of aggregated spin-torque nano-oscillators (ASTNOs), which share a magnetic propagation material. Each of the group of ASTNOs is...
8629103 Treatment of non-proliferative cystic disease of the breast  
The present invention relates generally to the treatment of non-proliferative cystic disease of the breast. More particularly, the present invention relates generally to the treatment of...
8614254 Methods and compositions for treating thalamocortical dysrhythmia  
This invention relates to methods of inhibiting a Cav3 calcium channel in a cell using a C2-C10 alkyl alcohol, or mixtures thereof. This invention further relates to methods of treating a...
US20130338225 Compounds As L-Cystine Crystallization Inhibitors And Uses Thereof  
A method of preventing or inhibiting L-cystine crystallization using the compounds of formula I is disclosed. wherein A, L, R1a, R1b, and m are as described herein. The compounds may be prepared as...
US20130336988 METHODS FOR TREATING EARLY STAGE OR MILD NEUROLOGICAL DISORDERS  
This disclosure relates to modulation of the interactions between proNTs and p75NTR/SorCS2 expressed on neuronal cells. Inhibition of such interactions is useful for reducing unwanted synaptic...
8612882 Method and apparatus for creating collections using automatic suggestions  
Method and apparatus for creating collections with automatic suggestions is disclosed. In one embodiment, a method comprises receiving a user specification containing at least one unquantified...
US20130332774 TEST ACCESS SYSTEM, METHOD AND COMPUTER-ACCESSIBLE MEDIUM FOR CHIPS WITH SPARE IDENTICAL CORES  
Exemplary system, method and computer-accessible medium for testing a multi-core chip can be provided which can have and/or utilize a plurality of identical cores. This can be performed by...
US20130331325 CHIMERIC FIBROBLAST GROWTH FACTOR 23 PROTEINS AND METHODS OF USE  
The present invention relates to a chimeric protein that includes an N-terminus coupled to a C-terminus, where the N-terminus includes a portion of a paracrine fibroblast growth factor (“FGF”) and...
US20130331317 CHIMERIC FIBROBLAST GROWTH FACTOR 19 PROTEINS AND METHODS OF USE  
The present invention relates to a chimeric protein that includes an N-terminus coupled to a C-terminus, where the N-terminus includes a portion of a paracrine fibroblast growth factor (“FGF”) and...
US20130331316 CHIMERIC FIBROBLAST GROWTH FACTOR 21 PROTEINS AND METHODS OF USE  
The present invention relates to a chimeric protein that includes an N-terminus coupled to a C-terminus, where the N-terminus includes a portion of a paracrine fibroblast growth factor (“FGF”) and...
8603179 Implants for the treatment of osteoarthritis of the knee  
A replacement knee implant has a femoral implant and a tibial implant, each of which are inset in a bone surface. The tibial implant is generally elongated with one end rounded and an opposite end...
US20130326204 Configuration-Preserving Preprocessor and Configuration-Preserving Parser  
Methods, systems, and apparatuses, including computer programs encoded on computer readable media, for generating a plurality of tokens from one or more source files that include source code in a...
8597645 Cancer treatment with endothelin receptor antagonists  
The present invention relates to therapeutic protocols and pharmaceutical compositions designed to treat and prevent cancer. More specifically, the present invention relates to a novel method of...