Patents and Patent Applications from New York University


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9605026 Hydrogen-bond surrogate peptides and peptidomimetics for p53 reactivation  
The present invention relates to peptidomimetics for reactivating p53. Methods of using the peptidomimetics are also disclosed.
9603876 Compositions and methods for restoring gastrointestinal microbiota following antibiotic treatment  
The present invention relates to characterizing changes in mammalian bacterial gastrointestinal, cutaneous and nasal microbiota associated with antibiotic treatment and various disease conditions...
9603792 System and method for correction of intracerebral chemical imbalances  
A method of treating a central nervous system (CNS) disorder, comprises the steps of inserting into a patient's body first and second conduits so that distal ends of the first and second conduits...
9602734 Methods, computer-accessible medium and systems for facilitating dark flash photography  
Exemplary embodiments of the present disclosure relate generally to methods, computer-accessible medium and systems for dark flash photography. For example, described herein is an exemplary...
9599671 Architecture, system, method, and computer-accessible medium for partial-scan testing  
Exemplary method, computer-accessible medium, test architecture, and system can be provided for a partial-scan test of at least one integrated circuit. For example, it is possible to obtain a...
9597377 Stable formulations of purified proteins  
This application provides methods of improving protein replacement therapy by combining protein replacement therapy with active site-specific chaperones (ASSC) to increase the stability and...
9593142 Aldehyde capture ligation technology for synthesis of amide bonds  
The present invention relates to ligation agents and their use in making an amide ligation product. Methods of making the ligation agents are also disclosed.
US20170066801 ALPHA3BETA HYDROGEN BOND SURROGATE MACROCYCLES AS MODULATORS OF RAS  
The present invention relates to peptides having a stable, internally-constrained HBS α-helix, where the peptide mimics at least a portion of the α-H helix of the Sos protein and contains a...
US20170065179 System And Method For In Vivo Detection Of Fluorescence From An Eye  
A system and method for in vivo detection and quantification of drusen present in the retina via administering an excitation signal to the retina of the eye and detecting an electromagnetic...
9591322 Coding using a redundant dictionary, such as video coding using a self-adaptive redundant dictionary including spatial and/or temporal prediction candidate atoms  
An example video encoder uses a self-adaptive dictionary that only depends on the block location, without requiring real time design/redesign of the dictionary. A mean-removed block may be...
9588203 Apparatus, method and computer-accessible medium for determination of electrical properties of tissues and materials using multiple radio frequency measurements  
An assembly for determining at least one electrical property of an object. The assembly includes at least one transmitter that can generate a plurality of electromagnetic field distribution...
9588202 Longevity of hyperpolarized enhanced signals for 1H NMR spectroscopy  
A method and system for providing an article of manufacture with increased longevity of hyperpolarized 1H signals (and other species) for NMR spectroscopy and MRI. The method involves providing a...
US20170064451 UBIQUITOUS SENSING ENVIRONMENT  
A system and method for selection and distribution of information from one or more remote sensing devices that are distributed in a space. Receiving such information from the remote sensing...
US20170063590 SYSTEM AND METHOD FOR MITIGATING FREQUENCY OFFSETS IN WIRELESS SYSTEMS  
Exemplary communication apparatus can comprise a receiver; a computer arrangement; and a non-transitory medium comprising computer-executable instructions that cause the apparatus to: receive a...
US20170059468 FAST FEATURE IDENTIFICATION FOR HOLOGRAPHIC TRACKING AND CHARACTERIZATION OF COLLOIDAL PARTICLES  
A method and system for identification of holographic tracking and identification of features of an object. A holograph is created from scattering off the object, intensity gradients are...
US20170058185 INHIBITION OF ASPHALTENE  
Methods, systems and compositions reduce or prevent the formation of asphaltene deposits by controlling the precipitation of asphaltene. An asphaltene inhibitor is utilized comprising an aromatic...
9582891 Method and apparatus for segmenting an image in order to locate a part thereof  
A method is disclosed to automatically segment 3D and higher-dimensional images into two subsets without user intervention, with no topological restriction on the solution, and in such a way that...
9582695 Computations using a polychronous wave propagation system  
The present invention relates to a polychronous wave propagation system that is based on relative timing between two or more propagated waves through a wave propagation medium. The relative timing...
9579404 Lanthanoid complex capsule and particle contrast agents, methods of making and using thereof  
The invention relates to compositions of DOTA derivative compounds, lanthanoid-DOTA derivative molecular complex, and lanthanoid-complex encapsulated solid lipid particles or capsules, and methods...
9579364 Methods for treating benign prostatic hypertrophy (BPH)  
Therapeutic methods for treating a subject with benign prostatic hypertrophy by inhibition of the activity of insulin-like growth factor-I (IGF-I) to reduce the amount of prostatic hyperplastic...
US20170053740 WINDING FOR LOW-VOLTAGE COILS OF DISTRIBUTION-CLASS TOROIDAL TRANSFORMERS  
A novel winding method is described herein which eliminates the circulating currents for wound transformers. A first layer of a wire is wound about the core at a first set of angles. Next, a loop...
US20170053215 TASK-AGNOSTIC INTEGRATION OF HUMAN AND MACHINE INTELLIGENCE  
A system combines inputs from human processing and machine processing, and employs machine learning to improve processing of individual tasks based on comparison of human processing results. Once...
9574015 Methods for treating muscle specific receptor kinase (MuSK) myasthenia gravis with the Ig1 domain of MuSK  
Agents, compositions, and medicaments that reduce interactions between muscle specific kinase receptor (MuSK) and pathogenic immunoglobulin G4 (IgG4) antibodies specific for the first Ig-like...
9574001 Humanized single-chain antibody against beta 3 integrin for the treatment and prevention of metastasis  
The present invention relates to methods inhibiting tumor metastasis and treating cancer in a subject that involve administering to the subject an antibody which recognizes GPIIIa49-66, under...
US20170044099 COVALENTLY PATTERNED GRAPHENE SURFACES BY A FORCE ACCELERATED CYCLOADDITION REACTION  
The present invention relates generally to molecular printing techniques for use in sensors, assays, and integrated optics and electronics. Specifically, the present invention relates to covalent...
US20170042904 METHODS FOR TREATING T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA  
The present invention is directed to methods of treating T-ALL that involve administering an inhibitor of jumonji D3 (JMJD3) demethylase. Another embodiment of the invention relates to methods...
9567378 In situ oriented immobilization of proteins on a support  
The present invention relates to a method of directing in situ oriented immobilization of a protein on a support. This method involves providing a support and contacting the support with a...
US20170037033 OXOPIPERAZINE HELIX MIMETICS AS INHIBITORS OF THE p53-MDM2 INTERACTION  
The present invention relates to oligooxopiperzines for modulating the p53-Mdm2 interaction. Methods of using the oligooxopiperazines are also disclosed.
US20170035795 METHODS AND REAGENTS FOR THE DIAGNOSIS AND TREATMENT OF ACUTE LEUKEMIA  
The present invention is directed to methods of treating T-ALL that involves administering a therapeutic agent that inhibits a NOTCH-1 regulated non-coding RNA (lncRNA). Another embodiment of the...
US20170035316 Minimally Invasive Subgaleal Extra-Cranial Electroencephalography (EEG) Monitoring Device  
A system includes an implantable body configured for implantation in a subgaleal extracranial position, the implantable body including a first electrode array including a first elongated body...
9563101 Common-path noncollinear optical parametric amplifier  
Systems and methods for providing a noncollinear optical parametric amplifier (NOPA). Two approaches for classes of NOPA are described: phase-mask NOPA and Wollaston NOPA.
9562892 Methods and agents for modulating protocadherin-18 activity  
Screening assays and methods of using same for screening to identify modulator agents or compounds that affect pcdh18 mediated inhibition of T cell effector function are described herein....
US20170029480 CHIMERIC FIBROBLAST GROWTH FACTOR 21 PROTEINS AND METHODS OF USE  
The present invention relates to a chimeric protein that includes an N-terminus coupled to a C-terminus, where the N-terminus includes a portion of a paracrine fibroblast growth factor (“FGF”) and...
9554997 Polymer carrier  
Compositions and methods for delivering bioactive agents, such as vitamins, hormones, nutrients and drugs, by stabilizing and or solubilizing these agents in a polymer matrix. The carrier polymers...
US20170024900 SYSTEM AND METHOD FOR DETERMINING MOTION AND STRUCTURE FROM OPTICAL FLOW  
A method and system for extracting motion and structure from a sequence of images stored on a computer system, the method comprises obtaining images including a set of three-dimensional (3D)...
US20170023681 PERSONAL AND SELF INDICATING RADIATION ALERT DOSIMETER  
Described is a self-indicating instant radiation dosimeter (1001) for monitoring high energy radiations, such as X-ray. The dosimeter contains a radiation sensitive, color changing, indicating...
US20170020674 REPLICA GUIDED MOTION KNEE  
A total knee replacement, comprising a femoral and a tibial component in articulating contact that can restore normal joint function. The articulation between the two components is controlled by...
9551002 Pericycle-specific expression of microRNA167 in plants  
Provided herein are compositions and methods for producing transgenic plants. In specific embodiments, transgenic plants comprise a construct comprising a polynucleotide encoding microRNA167...
9550820 Chimeric fibroblast growth factor 23/fibroblast growth factor 19 proteins and methods of use  
The present invention relates to an isolated chimeric protein. The isolated chimeric protein includes an N-terminus coupled to a C-terminus, where the N-terminus includes an N-terminal portion...
US20170016062 SEQUENCING METHODS AND KITS  
A method for detecting rare genomic variants in a population of cells is disclosed. The method can detect de novo mutations in bacteria and analyze the impact of various physiological conditions...
US20170015991 HYBRID POLYMERS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF SYNTHESIZING THE SAME  
Novel hybrid polymers are disclosed that have a structure represented by the following formula I: wherein Abiotic oligomer, Polypeptide, X, Y, and R1 are as described herein. The methods to...
US20170014351 ENGINEERED FLUORINATED BIOMATERIALS  
Provided are protein polymers providing the dual functionality of delivery and imaging. The protein polymers comprise a coiled-coil domain of the cartilage oligomeric matrix protein and repeats of...
US20170011330 SIGNALING GAME MACHINE ARCHITECTURE, SYSTEM, SOFTWARE, COMPUTER-ACCESSIBLE MEDIUM AND HARDWARE  
An exemplary system, method and computer accessible medium can be provided that can include generating a digital secure storage area(s) for a user(s), generating, in the secure storage area(s), a...
US20170009207 IN-VITRO BIOREACTOR  
An in vitro chamber for mimicking the mechanical and electrical forces found in vivo under physiological or pathological state. A chamber provides conditioning stimuli. The conditioning stimuli...
US20170008953 METHODS OF TREATING AND PREVENTING STAPHYLOCOCCUS AUREUS INFECTIONS AND ASSOCIATED CONDITIONS  
The present invention relates to methods and compositions for preventing and treating Staphylococcus aureus in a subject. Therapeutic compositions of the present invention comprise leukocidin E...
US20170008405 RESONANT INVERTER TOPOLOGY, WIRELESS CHARGER, AND CONTROL METHOD  
A wireless charger for an electric vehicle and a resonant inverter comprising a resonant portion that serially connects to a phase shifting portion and serially connects with a load component and...
US20170007876 Exercise Apparatus  
An exercise apparatus having a first and a second guide rails. The exercise apparatus further has a first and a second handle, the first handle being mounted on the first guide rail and configured...
9542162 Configuration-preserving preprocessor  
Methods, systems, and apparatuses, including computer programs encoded on computer readable media, for generating a plurality of tokens from one or more source files. The one or more source files...
9539315 Methods, agents and peptides for inhibiting matrix metalloproteinase-2 signaling  
Screening assays and methods of using same for screening to identify modulator agents or compounds that affect matrix metalloproteinase-2 (MMP-2) mediated activation of toll-like receptor-2...
US20170000520 POSITION GUIDANCE DEVICE WITH BUBBLE LEVEL  
A position guidance system for minimally invasive medical procedures includes a medical device having a first end configured for percutaneous insertion and a second end configured to remain...