|
Match
|
Document |
Document Title |
|
|
8447392 |
Brain-machine interface systems and methods
A system and method for interfacing a brain with a machine. An exemplary embodiment of the present invention employs a vascular approach in which one or more nano-electrodes are deployed in...
|
|
|
8444996 |
Multicomponent vaccine for malaria providing long-lasting immune responses against plasmodia
Disclosed are immunogenic conjugates which elicit an immune response to Plasmodium proteins. In particular examples, the Plasmodium proteins include sexual stage surface proteins, circumsporozoite...
|
|
|
US20130123885 |
APPARATUS, SYSTEMS, COMPUTER-ACCESSIBLE MEDIUM AND METHODS FOR FACILITATING RADIO FREQUENCY HYPERTHERMIA AND THERMAL CONTRAST IN A MAGNETIC RESONANCE IMAGING SYSTEM
The present disclosure can provide exemplary apparatus, system, methods, and computer-accessible medium for generating a prediction model for at least one of an electromagnetic radiation absorption...
|
|
|
US20130123306 |
Inhibition of Mitogen-activated Protein Kinases in Cardiovascular Disease
The present invention relates to methods for inhibiting subacute thrombosis and/or intimal hyperplasia following an interventional vascular procedure by contacting a blood vessel or a synthetic...
|
|
|
US20130123196 |
THIOETHER-, ETHER-, AND ALKYLAMINE-LINKED HYDROGEN BOND SURROGATE PEPTIDOMIMETICS
Provided herein are peptidomimetics and their salts having a stable, internally constrained protein secondary structure containing a thioether-, ether-, or alkylamine-linked hydrogen bond...
|
|
|
US20130123138 |
COMPOSITIONS AND METHODS FOR PROGNOSIS OF MESOTHELIOMA
Disclosed are compositions and methods for the prognosis of mesothelioma patients after surgical operation. Specifically the disclosure provides microRNA (miRNA) molecules associated with prognosis...
|
|
|
US20130121067 |
HIGH SPEED LOW POWER MAGNETIC DEVICES BASED ON CURRENT INDUCED SPIN-MOMENTUM TRANSFER
A high speed, low power method to control and switch the magnetization direction and/or helicity of a magnetic region in a magnetic device for memory cells using spin polarized electrical current....
|
|
|
8441481 |
Method and apparatus for segmenting an image in order to locate a part thereof
A method is disclosed to automatically segment 3D and higher-dimensional images into two subsets without user intervention, with no topological restriction on the solution, and in such a way that...
|
|
|
8436018 |
Method for increasing the activity of lysosomal enzymes
Method for enhancing in a mammalian cell the activity of an enzyme associated with Gaucher Disease by administering a competitive inhibitor of glucocerebrosidase in an amount effective to enhance...
|
|
|
8435948 |
Methods for inhibiting osteoclastic bone resorption and bone loss comprising administration of an anti-FSH or anti-FSHR antibody
The invention discloses compositions and methods for decreasing osteoclast which are useful for the treatment of a variety of bone loss disorders.
|
|
|
US20130107007 |
Constructing a 3-Dimensional Image from a 2-Dimensional Image and Compressing a 3-Dimensional Image to a 2-Dimensional Image
Systems and methods for receiving a blurred two-dimensional image captured using an optic system. The blurred two-dimensional image is deconvoluted using a point spread function for the optic...
|
|
|
US20130107006 |
CONSTRUCTING A 3-DIMENSIONAL IMAGE FROM A 2-DIMENSIONAL IMAGE AND COMPRESSING A 3-DIMENSIONAL IMAGE TO A 2-DIMENSIONAL IMAGE
Systems and methods for receiving a blurred two-dimensional image captured using an optic system. The blurred two-dimensional image is deconvoluted using a point spread function for the optic...
|
|
|
8431884 |
Holographic microfabrication and characterization system for soft matter and biological systems
A method and system for micromanipulation of objects of any shape. The method and system creates various forms of holographic optical traps for a variety of commercial purposes. Some alternate...
|
|
|
8431687 |
Staphylococcus aureus leukocidins, therapeutic compositions, and uses thereof
Disclosed herein are isolated and purified Staphylococcus aureus bi-component leukocidin, referred to herein as LukAB, and its components LukA and LukB, antibodies specific to LukA, antibodies...
|
|
|
US20130097194 |
APPARATUS, METHOD, AND COMPUTER-ACCESSIBLE MEDIUM FOR DISPLAYING VISUAL INFORMATION
A method for displaying visual information corresponding to at least one user can including receiving a selection of at least one attribute to be viewed, with a computer arrangement, tracking at...
|
|
|
US20130095115 |
STAPHYLOCOCCUS AUREUS LEUKOCIDINS, THERAPEUTIC COMPOSITIONS, AND USES THEREOF
Disclosed herein are isolated and purified Staphylococcus aureus bi-component leukocidin, referred to herein as LukAB, and its components LukA and LukB, antibodies specific to LukA, antibodies...
|
|
|
8420601 |
Biocompatible materials containing stable complexes of TSG-6 and hyaluronan and method of using same
The present invention provides a biocompatible material in the form of a water insoluble cross-linked gel, which contains a stable complex of TNF-stimulated gene 6 protein (TSG-6) and hyaluronan.
|
|
|
US20130090255 |
Biological Markers of Chronic Wound Tissue and Methods of Using for Criteria in Surgical Debridement
The present invention relates to methods for identifying tissue sites in a chronic wound that are suitable for debridement and whether debridement procedure has been successful using particular...
|
|
|
8409584 |
Immunotherapy targeting of the shared abnormal conformational state of amyloidogenic peptides/proteins
The present invention is directed to pharmaceutical agents and compositions useful for the treatment and prevention of amyloid disease in a subject. The invention further relates to isolated...
|
|
|
US20130080101 |
SYSTEM, METHOD AND COMPUTER-ACCESSIBLE MEDIUM FOR EVALUATING A MALIGNANCY STATUS IN AT-RISK POPULATIONS AND DURING PATIENT TREATMENT MANAGEMENT
In accordance with certain exemplary embodiments of the present disclosure, exemplary visualization system, method, procedure and computer-accessible medium can be provided, which individually...
|
|
|
US20130079385 |
USP47 Inhibtors and Methods to Induce Apoptosis
The present invention relates to USP47 (ubiquitin specific protease 47) inhibitors and methods for inducing apoptosis or cell death in a target cell. In certain embodiments, the invention relates...
|
|
|
US20130078231 |
DOSE ESCALATION ENZYME REPLACEMENT THERAPY FOR TREATING ACID SPHINOGMYELINASE DEFICIENCY
The invention relates to dose escalation enzyme replacement therapy using acid sphingomyelinase (ASM) for the treatment of human subjects having acid sphingomyelinase deficiency (ASMD), and, in...
|
|
|
US20130078230 |
DOSE ESCALATION ENZYME REPLACEMENT THERAPY FOR TREATING ACID SPHINOGMYELINASE DEFICIENCY
The invention relates to dose escalation enzyme replacement therapy using acid sphingomyelinase (ASM) for the treatment of human subjects having acid sphingomyelinase deficiency (ASMD), and, in...
|
|
|
8406889 |
Conducting polymer nanowire brain-machine interface systems and methods
The present invention relates to conducting polymer nanowires and their use in a brain-machine interface which is secure, robust and minimally invasive. In accordance with a first aspect of the...
|
|
|
8404482 |
Methods for in vitro differentiation of Th-17+ cells
The present invention is directed to an in vitro method for promoting differentiation and proliferation of human T helper lymphocytes that express IL17 (Th-IL17+ cells). The instant method may be...
|
|
|
8404442 |
Methods for identification of bone anabolic agents
The present invention is related to methods for identifying bone anabolic agents and factors, identifying pathways that promote proliferation of osteoblasts for bone growth and/or repair, and for...
|
|
|
US20130071424 |
PEPTIDES MIMICKING HIV-1 VIRAL EPITOPES IN THE V2 LOOP FOR THE GP120 SURFACE ENVELOPE GLYCOPROTEIN
The present invention relates to an isolated immunogenic peptide comprising a V2 loop fragment from HIV surface envelope glycoprotein gp120. This peptide binds specifically with antibodies in blood...
|
|
|
US20130063145 |
APPARATUS, SYSTEMS AND METHODS FOR FACILITATING SIGNAL EXCITATION AND/OR RECEPTION IN A MAGNETIC RESONANCE SYSTEM
In accordance with certain exemplary embodiments of the present disclosure, provided herein are apparatus, systems and methods for, e.g., faciliatating signal excitation and/or reception in a...
|
|
|
8394811 |
Hydrazide compounds as thyroid hormone receptor modulators and uses thereof
A method of identification of compounds that modulate thyroid hormone activity, and the use of such compounds and compositions thereof for such purposes are disclosed. The compounds may be selected...
|
|
|
8394708 |
Assembly of quasicrystalline photonic heterostructures
A method and system for assembling a quasicrystalline heterostructure. A plurality of particles is provided with desirable predetermined character. The particles are suspended in a medium, and...
|
|
|
8389482 |
Short peptides useful for treatment of ischemia/reperfusion injury and other tissue damage conditions associated with nitric oxide and its reactive species
This invention discloses isolated short peptides comprising the amino acid sequence Cys-Glu-Phe-His (CEFH; SEQ ID NOS: 1 and 15) and analogs thereof as well as compositions comprising CEFH peptides...
|
|
|
US20130045918 |
Methods for Treating Diabetic Wounds
The present invention relates to a method of treating chronic wounds using calreticulin. In particular, the invention relates to the treatment of chronic diabetic wounds using topical application...
|
|
|
US20130045879 |
METHODS, COMPUTER-ACCESSIBLE MEDIUM, AND SYSTEMS FOR GENERATING A GENOME WIDE HAPLOTYPE SEQUENCE
Methods, computer-accessible medium, and systems for generating a genome wide probe map and/or a genome wide haplotype sequence are provided. In particular, a genome wide probe map can be generated...
|
|
|
US20130045216 |
Method for Treating Amyloid Disease
Disclosed herein are methods for treating amyloid disease in humans by clearing amyloid peptides from one or more bodily fluids such as, e.g., blood, of a patient. In particular, the methods are...
|
|
|
8377871 |
Dendrimeric peptides, pharmaceutical compositions and methods of using the same
Novel dendrimeric peptide compounds are disclosed that have a formula represented by the following formula I: The compounds demonstrate antimicrobial activity and may be prepared as pharmaceutical...
|
|
|
US20130039885 |
LEUKOTOXIN E/D AS A NEW ANTI-INFLAMMATORY AGENT AND MICROBICIDE
The present invention relates to methods for preventing or treating Human Immunodeficiency Virus (HIV) infection, inflammatory conditions, and graft-versus-host-disease (GVHD) in a subject....
|
|
|
8372421 |
Inhibition of mitogen-activated protein kinases in cardiovascular disease
The present invention relates to methods for inhibiting subacute thrombosis and/or intimal hyperplasia following an interventional vascular procedure by contacting a blood vessel or a synthetic...
|
|
|
8371300 |
System and method for circuits to allow CPAP to provide zero pressure
A system comprises a respiratory delivery arrangement adapted to cover at least one respiratory orifice of a patient. The system also comprises a first conduit having a first end and a second end,...
|
|
|
US20130035243 |
KLF6 ALTERNATIVE SPLICE FORMS AND A GERMLINE KLF6 DNA POLYMORPHISM ASSOCIATED WITH INCREASED CANCER RISK
Disclosed are methods of identifying and diagnosing certain types of cancers and pre-stages thereof in a patient by identifying alternatively spliced isoforms of wild type KLF6 (KLF6wt), in...
|
|
|
US20130034586 |
AVIRULENT ONCOLYTIC HERPES SIMPLEX VIRUS STRAINS ENGINEERED TO COUNTER THE INNATE HOST RESPONSE
The present invention relates to an avirulent, oncolytic herpes simplex virus modified from a wild-type herpes simplex virus so that both γ134.5 genes of the virus have been deleted and each ...
|
|
|
8368399 |
Mode-scanning excitation magnetic resonance imaging method and system
A method, apparatus and computer-readable medium are provided for generating a specified transmit magnetic field profile in the presence of an object. In particular, further transmitted magnetic...
|
|
|
US20130030322 |
TISSUE COLLECTION SYSTEM
The present invention relates to a tissue collection system. The system includes an outer housing, a first cylindrical fenestrated member within and immovable relative to the outer housing, a...
|
|
|
8363465 |
High speed low power magnetic devices based on current induced spin-momentum transfer
A high speed and low power method to control and switch the magnetization direction and/or helicity of a magnetic region in a magnetic device for memory cells using spin polarized electrical...
|
|
|
8362218 |
Peptides targeting TNF family receptors and antagonizing TNF action, compositions, methods and uses thereof
The present invention provides modulators of TNF, particularly peptides and their derivatives, particularly GEP peptides, which antagonize TNF and TNF-mediated responses, activity or signaling. The...
|
|
|
US20130022612 |
METHODS AND COMPOSITIONS FOR MALARIA PROPHYLAXIS
A composition for preventing malaria infection including a steric inhibitor of circumsporozoite protein cleavage. A pharmaceutical composition for preventing malaria infection including a steric...
|
|
|
US20130022544 |
IMMUNOTHERAPEUTIC MODULATION OF AMYLOIDOGENIC DISEASE USING NON-FIBRILLOGENIC, NON-AMYLOIDOGENIC POLYMERIZED PROTEINS AND PEPTIDES
The present invention is directed to polymerized products and compositions useful for the treatment and prevention of amyloid disease in a subject. The invention further relates to isolated...
|
|
|
US20130017203 |
METHODS OF TREATING AND PREVENTING STAPHYLOCOCCUS AUREUS INFECTIONS AND ASSOCIATED CONDITIONS
The present invention relates to methods and compositions for preventing and treating Staphylococcus aureus in a subject. Therapeutic compositions of the present invention comprise leukocidin E...
|
|
|
8352023 |
System and method for guidance of anesthesia, analgesia and amnesia
Described is a method and system which includes a first set of digital data generated by amplifying and digitizing brain waves of a patient before and after administration of initial doses of...
|
|
|
US20120329861 |
TREATMENT OF CANCER USING BENZOIC ACID DERIVATIVES
The present invention provides a method of treating cancer using benzoic acid derivatives, alone or in combination with standard treatments such as chemotherapy and radiotherapy. Also provided are...
|
|
|
US20120329828 |
Cocaine Analogs and Methods of Preparation and Uses Thereof
The invention provides novel cocaine analogs. The invention also provides a method of preparing cocaine analogs with control over the substituents installed at the C-1, C-2, C-3, C-4 and N-8...
|