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US20090312663 |
System and Method for Neurometric Analysis
A system, comprises a plurality of neurometric analyzing software modules operating on electroencephalogram (EEG) data, each module performing a defined task with respect to neurometric analysis of...
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7632816 |
Treatment of Alzheimer amyloid deposition
The present invention is directed to a method of preventing or treating Alzheimer's Disease or of inhibiting accumulation of amyloid-β deposits in a subject by administering to the subject an...
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7632801 |
Identification and use of antiviral compounds that inhibit interaction of host cell proteins and viral proteins required for viral replication
The present invention relates to the identification of host cell proteins that interact with viral proteins required for virus replication, and high throughput assays to identify compounds that...
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US20090300782 |
Targeted gene addition in stem cells
The present invention provides methods for adenoassociated virus-mediated site-specific integration of a transgene into a stem cell. Stem cells having a transgene integrated therein, and...
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US20090296462 |
HIGH SPEED LOW POWER MAGNETIC DEVICES BASED ON CURRENT INDUCED SPIN-MOMENTUM TRANSFER
A high speed and low power method to control and switch the magnetization direction and/or helicity of a magnetic region in a magnetic device for memory cells using spin polarized electrical...
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7622567 |
Multidimensional organization of heteromolecules by robust DNA motifs
Two dimensional polynucleic acid arrays are assembled from robust nucleic acid motifs as polygonal units. The polygonal units in an array have edges composed of nucleic acid multi-crossover domains...
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7622485 |
Method of enhancing lysosomal α-galactosidase A
A method of enhancing the activity of lysosomal α-Galactosidase A (α-Gal A) in mammalian cells and for treatment of Fabry disease by administration of 1-deoxy-galactonojirimycin and related...
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7622121 |
Heat shock proteins from Mycobacterium leprae and uses thereof
The present invention is directed to heat shock proteins from Mycobacterium leprae as well as their encoding polynucleotides and vectors and host cells containing these polynucleotides. These...
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US20090286693 |
MICROARRAYS OF TAGGED COMBINATORIAL TRIAZINE LIBRARIES
Triazine linkers can be used to prepare universal small molecule chips for functional proteomics and sensors. These triazine linker compounds are prepared by making a first building block by adding...
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US20090286252 |
NRIF3, NOVEL CO-ACTIVATOR FOR NUCLEAR HORMONE RECEPTORS
Nucleic acids encoding NRIF3 are described. Polypeptides having amino acid sequences of NRIF3 proteins are also provided. A method is also provided for isolating and cloning NRIF3 cDNA. NRIF3 is...
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7620734 |
System and method for distributing foveated data in a network
A system and method for executing a computer program in a network. The system includes a surrogate proxy processor which, when executing the computer program, is programmed to receive at least one...
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7618933 |
Treatment of follicular lymphomas using inhibitors of the LT pathway
Therapeutic uses of inhibitors of the Lymphotoxin Pathway to treat tumors, specifically to treat follicular lymphomas.
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US20090281446 |
SYSTEM AND DEVICE FOR SEIZURE DETECTION
A device comprises a head mounting arrangement sized and shaped to be worn on a user's head and a plurality of electrodes disposed on the arrangement so that, when the arrangement is worn on the...
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US20090281025 |
INHIBITION OF TUMOR GROWTH AND METASTASIS BY ATF2-DERIVED PEPTIDES
The present invention relates to novel therapies for cancer and, in particular, to therapies that are particularly suited to tumor cells resistant to other types of therapies, such as radiation...
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US20090275639 |
USP47 INHIBTORS AND METHODS TO INDUCE APOPTOSIS
The present invention relates to USP47 (ubiquitin specific protease 47) inhibitors and methods for inducing apoptosis or cell death in a target cell. In certain embodiments, the invention relates...
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7612184 |
Polynucleic acid nanomechanical device controlled by hybridization topology
The present invention is directed to a sequence dependent polynucleotide nanomechanical device based on a nucleic acid paranemic crossover (PX) molecule which is a four-stranded structure related...
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US20090269314 |
HUMAN CARDIOVASCULAR PROGENITOR CELLS
The present invention provides populations of human cardiovascular progenitor cells, methods of making such cells, and methods of using the cells for production of populations of cardiovascular...
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7604995 |
Compositions, kits, and methods for stimulation of homologous recombination
A method of stimulating homologous recombination by creating at least one nick in a targeted polynucleotide sequence. Wherein nonhomologous recombination is suppressed resulting in increasing the...
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7604949 |
Methods and compositions that affect melanogenesis
The invention provides methods of screening for compounds that affect melanogenesis and the function of P protein in organisms, cells, or cell-free systems. The invention further relates to...
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7603331 |
System and method for dynamic profiling of users in one-to-one applications and for validating user rules
A system and method for generating and validating a user profile ( 25 ) for a user based on a static profile ( 10 ) and a dynamic profile ( 15 ) of the user. The method and system compresses the...
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7603323 |
Logic arrangement, data structure, system and method for multilinear representation of multimodal data ensembles for synthesis recognition and compression
A data structure, method, storage medium and logic arrangement are provided for use in collecting and analyzing multilinear data describing various characteristics of different objects. In...
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7601694 |
CLK-peptide and SLK-peptide
The invention describes methods for inhibiting angiogenesis in a tissue by administering an antagonist that specifically binds to a proteolyzed or denatured collagen type-IV with substantially...
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7598949 |
Multi-touch sensing light emitting diode display and method for using the same
Apparatus and method for both displaying graphical output and for sensing, e.g., multi-touch input are provided. A light-emitting diode (“LED”) matrix-array may be configured to both emit and...
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7598363 |
Polygonal nanostructures of polynucleic acid multi-crossover molecules and assembly of lattices based on double crossover cohesion
Robust nucleic acid arrays and lattices are assembled based on double crossover cohesion of polygonal units whose edges are composed of nucleic acid multi-crossover domains.
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7597015 |
Particle size sampler
A particle size sampler includes a cylindrical housing with an inlet end and an outlet end. A pump, connected to an outlet pipe at the outlet end, draws air through the particle size sampler....
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7592451 |
Treatment for diabetes and obesity as well as method of screening compounds useful for such treatments
The present invention relates to a compound having the formula
where Z is an amine, phenoxy, or thiol-containing group, and Y is an alkyl-containing amine. Methods of producing such compounds...
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US20090233933 |
Prostaglandin Transporter Inhibitors
Provided are methods of inhibiting prostaglandin transporter (PGT) activity in mammals. Also provided are methods of determining whether a test compound is an inhibitor of a prostaglandin...
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7589209 |
8-hydroxyquinoline tripodal metal ion probes
Highly sensitive fluorescent zinc or cadmium sensors are derived from 8-hydroxyquinaldine, a well-established fluorescent zinc probe, as a building block. High binding efficiency was achieved by...
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7589066 |
Potent and specific immunoproteasome inhibitors
Compounds and methods of selectively inhibiting an immunoproteasome are described. Also described are methods of treating a cancer, an inflammation, and/or an autoimmune disease and methods of...
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7588768 |
Attenuated negative strand viruses with altered interferon antagonist activity for use as vaccines and pharmaceuticals
The present invention relates, in general, to attenuated negative-strand RNA viruses having an impaired ability to antagonize the cellular interferon (IFN) response, and the use of such attenuated...
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US20090227889 |
Brain Function Scan System
A portable EEG (electroencephalograph) instrument, especially for use in emergencies and brain assessments in physicians' offices, detects and amplifies brain waves and converts them into digital...
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US20090227467 |
COMBINATORIAL ROSAMINE LIBRARY TO DETECT CELL-STATE SWITCHING
The present invention relates to the use of rosamine derivative compounds, as described herein, in detecting differentiated forms of a cell type of interest in a sample and in screening for...
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US20090226499 |
BIOCOMPATIBLE MATERIALS CONTAINING STABLE COMPLEXES OF TSG-6 AND HYALURONAN AND METHOD OF USING SAME
The present invention provides a biocompatible material in the form of a solid, a water insoluble cross-linked gel or a liposome, which contains a stable comples of TNF-stimulated gene protein...
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US20090226369 |
STQ Peptides
The invention describes methods for inhibiting angiogenesis in a tissue by administering an antagonist that specifically binds to a proteolyzed or denatured laminin with substantially greater...
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7586684 |
Solute characterization by optoelectronkinetic potentiometry in an inclined array of optical traps
A method and apparatus for selecting a specific fraction from a heterogeneous fluid-borne sample using optical gradient forces in a microfluidic or fluidic system are presented. Samples may range...
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US20090217391 |
T1R3 A NOVEL TASTE RECEPTOR
The present invention relates to the discovery, identification and characterization of a receptor protein, referred to herein as T1R3, which is expressed in taste receptor cells and associated with...
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US20090214425 |
TUMOR THERAPY WITH REPLICATION COMPETENT SINDBIS VIRAL VECTORS
Disclosed herein are methods for treating a mammal harboring a solid tumor which expresses higher levels of High Affinity Laminin Receptors (LAMR) than normal cells of the same lineage comprising...
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7573737 |
High speed low power magnetic devices based on current induced spin-momentum transfer
A high speed and low power method to control and switch the magnetization direction and/or helicity of a magnetic region in a magnetic device for memory cells using spin polarized electrical...
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US20090192569 |
CORTICAL ELECTRODE ARRAY AND METHOD FOR STIMULATING AND RECORDING BRAIN ACTIVITY
An electrode device and a method of installing the electrode device in the vicinity of the brain. The electrode device includes a plurality of electrode assemblies, each with at least one electrode...
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7566459 |
Modified mycobacterium tuberculosis strains and uses thereof
The present invention features modified Mycobacterium tuberculosis strains which lack a functional lspA gene, and vaccine formulations comprising the same. In many embodiments, a modified ...
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7566452 |
Cancer treatment with endothelin receptor antagonists
The present invention relates to therapeutic protocols and pharmaceutical compositions designed to treat and prevent cancer. More specifically, the present invention relates to a novel method of...
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US20090188009 |
HEAT SHOCK RNA FROM VARIOUS SPECIES AND ITS USE IN ACTIVATION OF HEAT SHOCK TRANSCRIPTION FACTOR, IN TREATMENT OF VARIOUS DISEASES IN ANIMALS AND IN GENERATION OF STRESS-RESISTANT PLANTS
The present invention provides a novel RNA, designated herein as the “HSR1” (Heat Shock RNA), and its use together with translation elongation factor eEF1A in activation of heat shock...
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US20090186829 |
Nitrosation-Inducible Inhibitors Biological Macromolecules
Biomacromolecules such as proteins are inactivated by hydrophobic ANSA derivatives of the formula:
wherein R 1 and R 2 are hydrophobic or affinity groups and R 3 is selected from the group...
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7563868 |
NRIF3, a novel co-activator for nuclear hormone receptors
Nucleic acids encoding NRIF3 are described. Polypeptides having amino acid sequences of NRIF3 proteins are also provided. A method is also provided for isolating and cloning NRIF3 cDNA. NRIF3 is...
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US20090182701 |
METHOD AND SYSTEM FOR DATA CLASSIFICATION IN THE PRESENCE OF A TEMPORAL NON-STATIONARITY
A method and system for determining a feature of a particular pattern are provided. In particular, data records are received, and predetermined patterns that are associated with at least some of...
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US20090181453 |
Mesoderm And Definitive Endoderm Cell Populations
The present invention provides cell populations that are enriched for mesendoderm and mesoderm, and cell populations that are enriched for endoderm. The cell populations of the invention are useful...
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US20090177246 |
Cochlear Implant Fitting System
A method comprises adjusting baseline auditory stimulation parameters of a cochlear implant on a living body and providing auditory electrical stimulation to a living body via electrodes of the...
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US20090175853 |
METHOD FOR TREATING AMYLOID DISEASE
Disclosed herein are methods for treating amyloid disease in humans by clearing amyloid peptides from one or more bodily fluids such as, e.g. blood, of a patient. In particular, the methods are...
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US20090163420 |
SYNTHETIC IMMUNOGENIC BUT NON-DEPOSIT-FORMING POLYPEPTIDES AND PEPTIDES HOMOLOGOUS TO AMYLOID BETA, PRION PROTEIN, AMYLIN, ALPHA-SYNUCLEIN, OR POLYGLUTAMINE REPEATS FOR INDUCTION OF AN IMMUNE RESPONSE THERETO
The present invention relates to immunogenic but non-depositing-forming polypeptides or peptides homologous to amyloid β, prion, amylin or α-synuclein which can be used alone or conjugated to an...
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US20090163407 |
COMPOSITIONS AND METHODS FOR ALTERING WNT AUTOCRINE SIGNALING
The present invention relates to compounds and methods for treating cancers in which the autocrine Wnt canonical signaling pathway is activated. In particular, there is provided a method for...
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