Patents and Patent Applications from New York University


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US20170044099 COVALENTLY PATTERNED GRAPHENE SURFACES BY A FORCE ACCELERATED CYCLOADDITION REACTION  
The present invention relates generally to molecular printing techniques for use in sensors, assays, and integrated optics and electronics. Specifically, the present invention relates to covalent...
US20170042904 METHODS FOR TREATING T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA  
The present invention is directed to methods of treating T-ALL that involve administering an inhibitor of jumonji D3 (JMJD3) demethylase. Another embodiment of the invention relates to methods...
9567378 In situ oriented immobilization of proteins on a support  
The present invention relates to a method of directing in situ oriented immobilization of a protein on a support. This method involves providing a support and contacting the support with a...
US20170037033 OXOPIPERAZINE HELIX MIMETICS AS INHIBITORS OF THE p53-MDM2 INTERACTION  
The present invention relates to oligooxopiperzines for modulating the p53-Mdm2 interaction. Methods of using the oligooxopiperazines are also disclosed.
US20170035795 METHODS AND REAGENTS FOR THE DIAGNOSIS AND TREATMENT OF ACUTE LEUKEMIA  
The present invention is directed to methods of treating T-ALL that involves administering a therapeutic agent that inhibits a NOTCH-1 regulated non-coding RNA (lncRNA). Another embodiment of the...
US20170035316 Minimally Invasive Subgaleal Extra-Cranial Electroencephalography (EEG) Monitoring Device  
A system includes an implantable body configured for implantation in a subgaleal extracranial position, the implantable body including a first electrode array including a first elongated body...
9563101 Common-path noncollinear optical parametric amplifier  
Systems and methods for providing a noncollinear optical parametric amplifier (NOPA). Two approaches for classes of NOPA are described: phase-mask NOPA and Wollaston NOPA.
9562892 Methods and agents for modulating protocadherin-18 activity  
Screening assays and methods of using same for screening to identify modulator agents or compounds that affect pcdh18 mediated inhibition of T cell effector function are described herein....
US20170029480 CHIMERIC FIBROBLAST GROWTH FACTOR 21 PROTEINS AND METHODS OF USE  
The present invention relates to a chimeric protein that includes an N-terminus coupled to a C-terminus, where the N-terminus includes a portion of a paracrine fibroblast growth factor (“FGF”) and...
9554997 Polymer carrier  
Compositions and methods for delivering bioactive agents, such as vitamins, hormones, nutrients and drugs, by stabilizing and or solubilizing these agents in a polymer matrix. The carrier polymers...
US20170024900 SYSTEM AND METHOD FOR DETERMINING MOTION AND STRUCTURE FROM OPTICAL FLOW  
A method and system for extracting motion and structure from a sequence of images stored on a computer system, the method comprises obtaining images including a set of three-dimensional (3D)...
US20170023681 PERSONAL AND SELF INDICATING RADIATION ALERT DOSIMETER  
Described is a self-indicating instant radiation dosimeter (1001) for monitoring high energy radiations, such as X-ray. The dosimeter contains a radiation sensitive, color changing, indicating...
US20170020674 REPLICA GUIDED MOTION KNEE  
A total knee replacement, comprising a femoral and a tibial component in articulating contact that can restore normal joint function. The articulation between the two components is controlled by...
9551002 Pericycle-specific expression of microRNA167 in plants  
Provided herein are compositions and methods for producing transgenic plants. In specific embodiments, transgenic plants comprise a construct comprising a polynucleotide encoding microRNA167...
9550820 Chimeric fibroblast growth factor 23/fibroblast growth factor 19 proteins and methods of use  
The present invention relates to an isolated chimeric protein. The isolated chimeric protein includes an N-terminus coupled to a C-terminus, where the N-terminus includes an N-terminal portion...
US20170016062 SEQUENCING METHODS AND KITS  
A method for detecting rare genomic variants in a population of cells is disclosed. The method can detect de novo mutations in bacteria and analyze the impact of various physiological conditions...
US20170015991 HYBRID POLYMERS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF SYNTHESIZING THE SAME  
Novel hybrid polymers are disclosed that have a structure represented by the following formula I: wherein Abiotic oligomer, Polypeptide, X, Y, and R1 are as described herein. The methods to...
US20170014351 ENGINEERED FLUORINATED BIOMATERIALS  
Provided are protein polymers providing the dual functionality of delivery and imaging. The protein polymers comprise a coiled-coil domain of the cartilage oligomeric matrix protein and repeats of...
US20170011330 SIGNALING GAME MACHINE ARCHITECTURE, SYSTEM, SOFTWARE, COMPUTER-ACCESSIBLE MEDIUM AND HARDWARE  
An exemplary system, method and computer accessible medium can be provided that can include generating a digital secure storage area(s) for a user(s), generating, in the secure storage area(s), a...
US20170009207 IN-VITRO BIOREACTOR  
An in vitro chamber for mimicking the mechanical and electrical forces found in vivo under physiological or pathological state. A chamber provides conditioning stimuli. The conditioning stimuli...
US20170008953 METHODS OF TREATING AND PREVENTING STAPHYLOCOCCUS AUREUS INFECTIONS AND ASSOCIATED CONDITIONS  
The present invention relates to methods and compositions for preventing and treating Staphylococcus aureus in a subject. Therapeutic compositions of the present invention comprise leukocidin E...
US20170008405 RESONANT INVERTER TOPOLOGY, WIRELESS CHARGER, AND CONTROL METHOD  
A wireless charger for an electric vehicle and a resonant inverter comprising a resonant portion that serially connects to a phase shifting portion and serially connects with a load component and...
US20170007876 Exercise Apparatus  
An exercise apparatus having a first and a second guide rails. The exercise apparatus further has a first and a second handle, the first handle being mounted on the first guide rail and configured...
9542162 Configuration-preserving preprocessor  
Methods, systems, and apparatuses, including computer programs encoded on computer readable media, for generating a plurality of tokens from one or more source files. The one or more source files...
9539315 Methods, agents and peptides for inhibiting matrix metalloproteinase-2 signaling  
Screening assays and methods of using same for screening to identify modulator agents or compounds that affect matrix metalloproteinase-2 (MMP-2) mediated activation of toll-like receptor-2...
US20170000520 POSITION GUIDANCE DEVICE WITH BUBBLE LEVEL  
A position guidance system for minimally invasive medical procedures includes a medical device having a first end configured for percutaneous insertion and a second end configured to remain...
9534020 Immunogenic polypeptides comprising a modified loop peptide presenting the HIV-1 GP120 3074 mAb epitope and scaffold proteins containing said peptide  
The present invention is directed to a recombinant immunogenic polypeptide. The polypeptide includes a loop peptide inserted into an immunogenic scaffold protein. The loop polypeptide has an amino...
9533115 System and method for diagnosis and treatment of a breathing pattern of a patient  
Described is a system including a sensor and a processing arrangement. The sensor measures data corresponding to a patient's breathing patterns. The processing arrangement analyzes the breathing...
9532889 Y-lock tracheal stent system and method of use  
A Y-Lock tracheal stent system consisting of a stent device, for emplacement in the larynx, and a stent delivery system. A method for employing the stent delivery system to emplace the stent device.
9526712 Methods and agents for preventing and treating plasma cell dyscrasias  
Screening assays and methods of using same for screening to identify modulator agents or compounds that target endoplasmic reticulum stress related signaling pathways to induce apoptosis are...
US20160367705 NANOPARTICLES COMPRISED OF SHELLS ASSOCIATED WITH CHARGED ENTITIES AND FORMED FROM MONOMERS AND METHODS OF MAKING AND USING NANOPARTICLES  
The present invention relates to relates to a nanoparticle that includes a shell formed from a first monomer having a first charge and a second monomer different than the first monomer. The first...
9524020 Sensor having a mesh layer with protrusions, and method  
A sensor having a set of grid of bars that are in contact from their bottom at the corners with a set of protrusions that are in contact from above with a plurality of intersections, each having a...
US20160364051 Sensor Having a Set of Plates, and Method  
A sensor having a set of plates that are in contact from their bottom at the corners with a set of protrusions that are in contact from above with a plurality of intersections, each having a...
US20160364047 Fusing Depth and Pressure Imaging to Provide Object Identification for Multi-Touch Surfaces  
An apparatus for inputting information into a computer includes a 3d sensor that senses 3d information and produces a 3d output The apparatus includes a 2d sensor that senses 2d information and...
9519348 Haptic force-feedback for computing interfaces  
Methods, systems, and apparatuses, including computer programs encoded on computer-readable media, provide two degrees of freedom active force feedback for touchscreens or any other general...
9519129 Method and system for measuring porosity of particles  
A method for analyzing porosity of a particle and a medium disposed in the porosity of the particle. A video-holographic microscope is provided to analyze interference patterns produced by...
US20160354451 METHOD OF PROVIDING PATIENT SPECIFIC IMMUNE RESPONSE IN AMYLOIDOSES AND PROTEIN AGGREGATION DISORDERS  
A treatment of Alzheimer's disease and other disorders involving protein misfolding or aggregation is provided by enhancing or sustaining an antibody response against predominantly directed...
US20160354438 THERAPEUTIC AND COSMETIC USES AND APPLICATIONS OF CALRETICULIN  
The invention relates to therapeutic and cosmetic uses of calreticulin including reducing or eliminating wrinkles and/or fine lines, tissue repair and reconstruction, repairing damaged bone and/or...
US20160354373 METHODS OF TREATING ACUTE T CELL LEUKEMIA  
The present invention is directed to methods of treating T-cell acute lymphoblastic leukemia. This method involves selecting a subject having T-cell acute lymphoblastic leukemia and administering,...
US20160347869 METHOD FOR SEPARATING HYALURONAN AND QUANTIFYING ITS MOLECULAR MASS DISTRIBUTION IN BIOLOGICAL SAMPLES  
The present invention provides a facile method for separation (fractionation) of HA in a sample over a broad M range, including low M HA, by ion exchange (IEX) chromatography. The present...
US20160346363 METHODS AND ORAL FORMULATIONS FOR ENZYME REPLACEMENT THERAPY OF HUMAN LYSOSOMAL AND METABOLIC DISEASES  
The invention provides methods, compositions and kits for enzyme replacement therapy as well as molecular constructs, cells, tissues and plants suitable for expressing recombinant enzymes....
9507734 Corrupting data structures for privacy protection  
Methods, systems, and apparatuses, including computer programs encoded on computer-readable media, for storing data in both defaultable and non-defaultable memory on a unit in such a way that if a...
9505798 Steroid compounds as RORyt modulators and uses thereof  
Steroid compounds are disclosed that have a formula represented by the following: and wherein m, n, t, u1, u2, v1, v2, R1a, R1b, R2a, R2b, R3a, R3b, R3c, R3d, and Y are as described herein. The...
US20160343129 SYSTEM, METHOD AND COMPUTER-ACCESSIBLE MEDIUM FOR DETERMINING BRAIN MICROSTRUCTURE PARAMETERS FROM DIFFUSION MAGNETIC RESONANCE IMAGING SIGNAL'S ROTATIONAL INVARIANTS  
An exemplary system, method and computer-accessible medium for determining a plurality of tissue parameters of a tissue(s), can include, for example, receiving information related to a plurality...
US20160341686 SIZE DEPENDENCE OF NANOPARTICLE-PROTEIN INTERACTION AND HIGH SENSITIVITY POTENTIOMETRIC SENSOR EXPLOITING SUCH INTERACTIONS  
Fabrication of a high sensitivity potentiometric biosensor is described. The present inventors have developed and characterized a novel amplification platform using a gold nanoparticle (GNPs)...
US20160340734 DETECTING GENETIC PREDISPOSITION TO OSTEOARTHRITIS ASSOCIATED CONDITIONS  
This application relates to methods and kits for detecting predisposition to increased risk for osteoarthritis associated conditions.
9498495 Methods for in vitro differentiation of TH-17+ cells  
The present invention is directed to an in vitro method for promoting differentiation and proliferation of human T helper lymphocytes that express IL17 (Th-IL17+ cells). The instant method may be...
US20160331792 METHODS FOR RESTORING MICROBIOTA OF NEWBORNS  
The invention relates to methods and compositions for restoring normal microbiota in pre-term newborns or newborns delivered by Cesarean section and methods for preventing or ameliorating diseases...
9492439 Amido compounds as RORγt modulators and uses thereof  
Amido compounds are disclosed that have a formula represented by the following: and wherein n1, n2, R1a, R1b, R2, R3, R4, R5, and R6 are as described herein. The compounds may be prepared as...
US20160330358 METHODS, COMPUTER-ACCESSIBLE MEDIUM AND SYSTEMS FOR FACILITATING DARK FLASH PHOTOGRAPHY  
Exemplary embodiments of the present disclosure relate generally to methods, computer-accessible medium and systems for dark flash photography. For example, described herein is an exemplary...