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Patents and Patent Applications from New York University


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9042974 Apparatus and method for monitoring and treatment of brain disorders  
A method and system for treating brain disorders comprises detecting activity of a first target area of the brain via a first implanted sensor and determining the presence of target brain activity...
9040261 Compounds as L-cystine crystallization inhibitors and uses thereof  
A method of preventing or inhibiting L-cystine crystallization using the compounds of formula I is disclosed. wherein A, L, R1a, R1b, and m are as described herein. The compounds may be prepared as...
US20150141480 CARBOHYDRATE-SELECTIVE RECEPTORS  
The present invention is directed to a new class of synthetic carbohydrate receptor compounds comprising Formula I as described herein: (I). Other aspects of the present invention relate to...
9035743 Song selection based upon axial pen pressure  
Methods, systems, and apparatuses, including computer programs encoded on computer readable media, for determining, using a pressure sensor, pressure data comprising a pressure indication and a...
US20150134266 METHOD OF IDENTIFYING THE MOLECULAR BASIS OF THE ACTIVITY OF A DRUG COMPOUND, PHARMACEUTICAL COMPOSITIONS, AND TREATMENT METHODS  
The present invention relates to a method of identifying the molecular basis of a drug compound's activity. The invention further relates to a pharmaceutical composition, a kit for treating...
US20150132310 METHODS OF TREATING AND PREVENTING STAPHYLOCOCCUS AUREUS INFECTIONS AND ASSOCIATED CONDITIONS  
The present invention relates to methods of treating and preventing Staphylococcus aureus infection and/or a condition resulting from a S. aureus infection a subject that involves administering a...
US20150130465 DIPOLE ARRAY ARRANGEMENT  
An apparatus can be provided that can include a plurality of electric dipole antenna arrangements, and a processing arrangement configured to receive a signal(s) from the electric dipole antenna...
US20150126621 METHOD FOR PREDICTING RECURRENCE OF MELANOMA USING miRNA ALTERATIONS  
Described herein are miRNA-based methods for prognosis of recurrence of melanoma and related methods and kits. The present invention addresses these and other needs by providing a method for...
US20150126450 MULTIVALENT PEPTOID OLIGOMERS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING SAME  
Novel peptoid oligomers are disclosed that have a formula represented by the following formula Ia or Ib: The peptoid oligomers are prepared as modulators of androgen receptor (AR), and may be...
US20150125476 IMMUNOGENIC PEPTIDES AND POLYPEPTIDES FOR PROTECTION AGAINST HIV INFECTION  
The present invention relates to an isolated immunogenic peptide chimera comprising a first peptide moiety comprising the amino acid sequence of SEQ ID NO: 1, or at least a contiguous 5 amino acid...
US20150125466 METHODS RELATED TO CANCER TREATMENT  
The present invention relates to method for predicting a subject's relative response to cancer immunotherapy treatment. The methods involve providing a sample comprising a tumor cell or a...
US20150125442 METHODS FOR TREATING MUSCLE SPECIFIC RECEPTOR KINASE MYASTHENIA GRAVIS  
Agents, compositions, and medicaments that reduce interactions between muscle specific kinase receptor (MuSK) and pathogenic immunoglobulin G4 (IgG4) antibodies specific for the first Ig-like...
US20150125441 METHODS OF TREATING DEPRESSION AND PAIN  
The present invention provides methods of treating and pharmaceutical compositions useful for treating a mood disorder or depressive symptoms associated with pain, inducing analgesia and treating...
9023788 Methods compounds and pharmaceutical compositions for treating anxiety and mood disorders  
Compounds and pharmaceutical compositions containing such compounds having formula I are provided: where R1, R2a, R2b, R3, R4, and R5 are as defined herein. The compounds and pharmaceutical...
9023111 Total knee replacement substituting function of anterior cruciate ligament  
A total knee replacement prosthesis comprising condylar and intercondylar bearing surfaces configured to manage anterior/posterior displacement between the articulating femoral and tibial components.
US20150120209 METHOD, COMPUTER-ACCESSIBLE MEDIUM, AND SYSTEMS FOR GENERATING A GENOME WIDE HAPLOTYPE SEQUENCE  
Methods, computer-accessible medium, and systems for generating a genome wide probe map and/or a genome wide haplotype sequence are provided. In particular, a genome wide probe map can be generated...
US20150119329 MODULATION OF ANGIOTENSIN II RECEPTORS FOR THE PREVENTION AND TREATMENT OF MALARIA CEREBRAL  
The present invention is directed to a composition for the treatment or prevention of cerebral malaria that comprises an angiotensin receptor type-2 agonist and an antimalaria drug. The present...
9020585 Electronic identity card  
A method comprises the steps of obtaining a baseline measurement corresponding to a representation of brain activity from a living body and storing the baseline measurements on a storage device...
9018259 Treatment of cancer using benzoic acid derivatives  
The present invention provides a method of treating cancer using benzoic acid derivatives, alone or in combination with standard treatments such as chemotherapy and radiotherapy. Also provided are...
US20150112066 ASYMMETRIC CATALYSTS  
The present invention relates to asymmetric catalysts, including redox-reconfigurable asymmetric catalysts. Methods of producing compounds having one or more stereocenters using the asymmetric...
US20150111764 POLYMERIZED MICROARRAYS  
Micropatterns of glycan-bearing brush polymers generated by the initiation of oligomerization of acrylate and methacrylate monomers from thiol-terminated surfaces. Chain lengths are controlled in...
US20150110822 ONCOLYTIC HERPES SIMPLEX VIRUS AND THERAPEUTIC USES THEREOF  
The present invention relates to variants of herpes simplex virus (HSV) that selectively infect and replicate in cancer cells, including HSV strains that selectively infect and replicate in bladder...
US20150110418 SEAM CARVING BASED ANONYMIZATION  
As image source attribution techniques have become significantly sophisticated and are now becoming commonplace, there is a growing need for capabilities to anonymize images and videos. Focusing on...
US20150107594 System and Method for Diagnosis and Treatment of a Breathing Pattern of a Patient  
Described is a system including a sensor and a processing arrangement. The sensor measures data corresponding to a patient's breathing patterns. The processing arrangement analyzes the breathing...
9005587 Anti-bacterial and mineralizing calcium phosphate compositions  
The present invention provides compositions including saturated calcium phosphate (sCaP) solutions, that may be prepared from mixtures of calcium deficient apatite and one or more of sodium...
US20150099806 COMPOUNDS AS L-CYSTINE CRYSTALLIZATION INHIBITORS AND USES THEREOF  
A method of preventing or inhibiting L-cystine crystallization is disclosed, using the compounds of formula I: R1a—[O]v-(-A-L-)m-A-[O]v—R1b I wherein A, L, R1a, R1b, m, and v are as described her...
US20150099700 METHODS FOR DETECTING PROGENITOR CELLS AND USES THEREOF  
Diagnostic and therapeutic methods pertaining to diseases and disorders of the breast, uterus and ovary are encompassed herein. More particularly, diagnostic methods for early detection of...
US20150096755 COMPOSITIONS COMPRISING CARBON DIOXIDE AND REVERSE MICELLES AND METHODS OF USE  
Provided herein is a composition comprising carbon dioxide, an aqueous phase, and reverse micelles, wherein the reverse micelles comprise a metal cation-chelating agent, and a metal cation; and...
8999935 Treatment of osteoporosis in peri- and post-menopausal women with hepcidin  
The present invention is directed to a method of treating, preventing, or reducing the risk of bone deterioration or osteoporosis in a peri- or post-menopausal female subject. The method involves...
8999929 Fibroblast growth factor 1 protein fragments and methods of use  
The present invention relates to a chimeric protein that includes an N-terminus coupled to a C-terminus, where the N-terminus includes a portion of a paracrine fibroblast growth factor (“FGF”) and...
8992933 Methods for activating T cells and modulating an immune response  
The present invention is directed to a method for promoting differentiation, activation and proliferation of human T helper lymphocytes such as those that express IL17 and IL22 (Th-IL17+ and...
8987412 Hydrogen bond surrogate macrocycles as modulators of Ras  
The present invention relates to peptides having one or more stable, internally-constrained HBS α-helices, where the peptide is capable of interacting with Ras and related proteins.
8982613 Scalable orthogonal spin transfer magnetic random access memory devices with reduced write error rates  
A magnetic device includes a pinned polarizing magnetic layer having a magnetic vector parallel to a plane of the pinned polarizing magnetic layer. The magnetic device also includes a free layer,...
8980284 Recombinant derivatives of botulinum neurotoxins engineered for trafficking studies and neuronal delivery  
This invention relates to isolated Clostridium botulinum propeptides and neurotoxins, isolated nucleic acid molecules encoding Clostridium botulinum propeptides and neurotoxins, methods of...
US20150072991 OLIGOOXOPIPERAZINES AND METHODS OF MAKING AND USING THEM  
The present invention relates to oligooxopiperazines and their use. Methods for preparing oligooxopiperazines are also disclosed.
US20150072364 METHODS AND KITS FOR DIAGNOSING OSTEOARTHRITIS AND PREDICTING PROGRESSION  
This disclosure relates to methods and kits for diagnosing osteoarthritis and for determining the progression of osteoarthritis in a subject.
US20150067923 Transgenic Plants And A Transient Transformation System For Genome-Wide Transcription Factor Target Discovery  
Plant genes regulated by transcription factors that control the gene network response to an environmental perturbation or signal are described. This class of genes responds to the perturbation of a...
US20150067288 CORRUPTING DATA STRUCTURES FOR PRIVACY PROTECTION  
Methods, systems, and apparatuses, including computer programs encoded on computer-readable media, for storing data in both defaultable and non-defaultable memory on a unit in such a way that if a...
US20150066594 SYSTEM, METHOD AND COMPUTER ACCESSIBLE MEDIUM FOR DETERMINING ONE OR MORE EFFECTS OF RANKINGS ON CONSUMER BEHAVIOR  
Exemplary systems, methods and computer-accessible mediums can be provided which can receive information related to a consumer(s), and determine the search behavior of the consumer(s) based on the...
US20150065436 INHIBITING INTERACTION BETWEEN HIF-1ALPHA AND p300/CBP WITH HYDROGEN BOND SURROGATE-BASED HELICES  
The present invention relates to peptidomimetics that mimic helix αB of the C-terminal transactivation domain of HIF-1α. Methods of using the peptidomimetics to, e.g., inhibit the H...
US20150065376 EXPRESSION CONSTRUCTS ENCODING G PROTEIN COUPLED RECEPTORS AND METHODS OF USE THEREOF  
Expression vectors comprising a first nucleic acid sequence encoding a G protein coupled receptor (GPCR), wherein the GPCR encoded thereby is expressed as a fusion protein with a first detectable...
US20150062587 HOLOGRAPHIC MICROREFRACTOMETER  
An in-line holographic microscope is used for measurements of micrometer-scale particles and associated suspending fluid medium containing the particles. The system yields heterodyne scattering...
US20150057759 MEDIAL TIBIAL PLATEAU REALIGNMENT PROCEDURE FOR MEDIAL OSTEOARTHRITIS OF THE KNEE  
A method and apparatus for correcting varus deformity comprises cutting a horizontal slot in the upper medial portion of the tibia. The slot is opened by the application of external force and a...
US20150055845 System, Method and Computer Accessible Medium for Providing Real-Time Diffusional Kurtosis Imaging and for Facilitating Estimation of Tensors and Tensor- Derived Measures in Diffusional Kurtosis Imaging  
Exemplary method, system, and computer-accessible medium can be provided for determining a measure of diffusional kurtosis by receiving data relating to at least one diffusion weighted image, and...
US20150054635 HAPTIC FORCE-FEEDBACK FOR COMPUTING INTERFACES  
Methods, systems, and apparatuses, including computer programs encoded on computer-readable media, provide two degrees of freedom active force feedback for touchscreens or any other general...
US20150054633 Interactive Tangible Interface for Hand Motion  
Methods, systems, and apparatuses, including computer programs encoded on computer-readable media are disclosed, for receiving, from an inertial measurement unit (IMU) the motion information of an...
8961987 Immunogen comprising the HIV GP120 V3 loop in a conformation that induces broadly neutralizing antibodies  
Insertion of HIV-1 V3 loop peptides from the viral glycoprotein gp120 into selected, immunogenic scaffold proteins results in a recombinant polypeptide that is a potent V3 immunogen. V3 immunogens...
US20150050289 MUSCLE SPECIFIC RECEPTOR KINASE AND MODULATION THEREOF  
Agents, compositions, and medicaments that pertain to modulating the activity of muscle specific kinase receptor (MuSK) and methods and uses thereof to modulate MuSK activity are encompassed...
US20150045766 MICROELECTRODE-EQUIPPED SUBDURAL THERAPEUTIC AGENT DELIVERY STRIP  
An apparatus for treating the brain, comprises a first fluid delivery device including a distal end sized and shaped for placement at a first target site between a dura mater and a pia mater of the...
US20150044243 MUCOSAL IMMUNIZATION TO PREVENT PRION INFECTION  
Vaccines against prion disease eliciting a humoral immune response when administered mucosally are described. The vaccines comprise a prion protein, a prion protein fragment, or a non-amyloidogenic...