Patents and Patent Applications from New York University


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US20180170910 ALPHA-HELIX MIMETICS AS MODULATORS OF ABETA SELF-ASSEMBLY  
The invention relates to compounds and pharmaceutical compositions capable of treating amyloid diseases and other diseases characterized by oligomerization and/or fibrillation of amyloidogenic...
US20180169144 Citrate Containing Beverage  
Provided are beverage compositions comprising a urine citrate increasing component and a urine oxalate reducing component. The beverage compositions may be provided in a ready-to-drink form or may...
10002444 System, method and computer-accessible medium for joint magnetic resonance-positron emission tomography reconstruction using multi-sensor compressed sensing  
An exemplary system, method and computer-accessible medium for generating a magnetic resonance (MR) image(s) and a positron emission tomography (PET) image(s) of a tissue(s) can be provided, which...
US20180161339 USE OF CARBONIC ANHYDRASE INHIBITORS FOR TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS  
The invention is directed to the use of carbonic anhydrase inhibitors for treatment of neurological and psychiatric disorders.
US20180157574 POST-SILICON VALIDATION AND DEBUG USING SYMBOLIC QUICK ERROR DETECTION  
Disclosed are improved methods and structures for verifying integrated circuits and in particular systems-on-a-chip constructed therefrom. We call methods and structures according to the present...
US20180156807 METHOD FOR TREATING HIGH-GRADE GLIOMAS  
The invention is directed to a method for inhibiting growth, self-renewal, or tumorigenicity of glioma cells and a method for treating high-grade gliomas by inhibiting GPR133 expression and/or...
9989451 Method and system for measuring porosity of particles  
A method for analyzing porosity of a particle and a medium disposed in the porosity of the particle. A video-holographic microscope is provided to analyze interference patterns produced by...
9989422 System, method and computer accessible medium for determining tissue thermal property  
An exemplary system, method and computer-accessible medium for constructing information regarding a distribution of thermal properties of an object(s), can be provided. For example, data related...
9988424 Immunogens comprising human immunodeficiency virus V1/V2 polypeptides  
The invention is generally directed to V1V2 immunogens.
US20180146840 ENDOSCOPIC MEASURING DEVICE  
A device and system for measuring anatomical features includes a flexible member sized to pass slidably through a first lumen of an insertion instrument, a control element, and a measuring device...
9983194 Cancer diagnostics, therapeutics, and drug discovery associated with macropinocytosis  
The present invention is directed to methods of inhibiting both proliferation and survival of cancer cells and for treating a subject having cancer. The present invention is further directed to...
9981237 Higher order multiple emulsions  
Multiple emulsions with an “onion” topology are useful vehicles for drug delivery, biochemical assays, and templating materials. They can be assembled by ternary liquid phase separation using...
US20180145504 REDUCTION OF GEOMAGNETICALLY INDUCED CURRENTS  
Methods, systems, and apparatuses are disclosed for reducing geomagnetically-induced currents. The method includes connecting a plurality of switching devices at a neutral grounding connection...
US20180141019 SELF-INFLATING MICROCAPSULES  
A method comprises providing an aqueous solution having an alkaline pH and providing an oil including at least one silsesquioxane compound. The oil is added to the aqueous solution. The oil forms...
US20180140217 COMPUTER-ACCESSIBLE MEDIUM FOR DETERMINING ARTERIAL INPUT FUNCTION  
An exemplary system, method and computer-accessible medium for determining an arterial input function (AIF) of a mammal(s) can be provided, which can include, for example, receiving information...
9975441 Uniform magnetic field transmitter  
A system for wirelessly charging an electric vehicle comprises a wireless charging coil having a first end, a second end, and a plurality of turns. The first end has a first turn having a first...
9975084 Fluid separation processes using membranes based on fluorinated and perfluorinated polymers  
A process for separating components or a fluid mixture using membranes comprising a selective layer made from copolymers of an amorphous per fluorinated dioxolane and a fluorovinyl monomer. The...
US20180136207 PEPTIDES OF M. TUBERCULOSIS FOR A SCREENING TEST FOR HIV POSITIVE PATIENTS AT HIGH-RISK FOR TUBERCULOSIS  
Provided are peptides suitable for early detection of active M. tuberculosis (Mtb) infection in immunocompromised individuals. The peptides can form complexes with antibodies directed to Mtb...
9972914 Monopole array arrangement, computer-accessible medium and method for using the same  
An array arrangement according to an exemplary embodiment of the present disclosure can be provided. For example, the array arrangement can include a monopole array having a first end and a second...
9969782 Highly immunogenic peptides derived from the human immunodeficiency virus V2 region  
The present invention relates to an isolated immunogenic peptide chimera comprising a first peptide moiety comprising the amino acid sequence of SEQ ID NO: 1, or at least a contiguous 5 amino acid...
9969773 Polymers, pharmaceutical compositions and methods of synthesizing the same  
Novel methods to prepare novel polymers are disclosed. Oxazolidinyl compounds according to formula IV: are also disclosed as intermediate compounds that can be reacted with an acid to form a...
US20180129961 SYSTEM, METHOD AND COMPUTER-ACCESSIBLE MEDIUM FOR MAKING A PREDICTION FROM MARKET DATA  
An exemplary system, method and computer-accessible medium for generating a model(s), can include, for example, receiving first information related to raw data, generating second information by...
US20180127769 TRANSGENIC PLANTS AND A TRANSIENT TRANSFORMATION SYSTEM FOR GENOME-WIDE TRANSCRIPTION FACTOR TARGET DISCOVERY  
Plant genes regulated by transcription factors that control the gene network response to an environmental perturbation or signal are described. This class of genes responds to the perturbation of...
US20180125900 PROBIOTIC COMPOSITIONS FOR IMPROVING METABOLISM AND IMMUNITY  
The application relates to methods based on modulating mammalian intestinal microbiota and related probiotic and prebiotic compositions. Specifically, the application relates to the use of novel...
9965862 System, method and computer accessible medium for providing real-time diffusional kurtosis imaging and for facilitating estimation of tensors and tensor-derived measures in diffusional kurtosis imaging  
Exemplary method, system, and computer-accessible medium can be provided for determining a measure of diffusional kurtosis by receiving data relating to at least one diffusion weighted image, and...
US20180124082 CLASSIFYING LOGINS, FOR EXAMPLE AS BENIGN OR MALICIOUS LOGINS, IN PRIVATE NETWORKS SUCH AS ENTERPRISE NETWORKS FOR EXAMPLE  
Logins within a private network are classified as benign or malicious by (a) receiving login patterns within a private network, wherein each login pattern includes one or more attributes of each...
US20180120404 SYSTEM, METHOD AND COMPUTER ACCESSIBLE MEDIUM FOR NOISE ESTIMATION, NOISE REMOVAL AND GIBBS RINGING REMOVAL  
An exemplary system, method and computer-accessible medium for removing noise and Gibbs ringing from a magnetic resonance (“MR”) image(s), can be provided, which can include, for example,...
US20180117331 Minimally Invasive Subgaleal Extra-Cranial Electroencephalography EEG Monitoring Device  
A system includes an implantable body configured for implantation in a subgaleal extracranial position, the implantable body including a first electrode array including a first elongated body...
9956529 Microfabricated ion-selective filter for filtration of ions and molecules  
A microfabricated filtration membrane including a substrate containing a plurality of micropores, an ion-selective layer, and at least two conductive layers configured to apply a voltage across...
US20180110845 METHOD OF PROVIDING PATIENT SPECIFIC IMMUNE RESPONSE IN AMYLOIDOSES AND PROTEIN AGGREGATION DISORDERS  
A treatment of Alzheimer's disease and other disorders involving protein misfolding or aggregation is provided by enhancing or sustaining an antibody response against predominantly directed...
US20180110770 FERROPTOSIS AND GLUTAMINOLYSIS INHIBITORS AND METHODS OF TREATMENT  
The present invention is directed to ferroptosis and glutaminolysis inhibitors and to methods of treatment or prevention of an organ injury caused by ischemia-reperfusion in a subject in need...
US20180107782 ATOMIC MODEL FOR JANUS KINASE-2 (JAK2) AND USES THEREOF  
Atomic or molecular models of the autoinhibitory interaction between JAK domains are provided along with methods using the atomic models for identifying agents that restore the autoinhibitory...
9943398 Increasing survival of free tissue grafts and flaps using phosphodiesterase type 5 (PDE5) inhibitors  
The present invention relates to methods of tissue grafting and microvascular free flap transfer that involve administering a phosphodiesterase type-5 inhibitor to the tissue graft or...
US20180102240 REAGENTS AND METHODS FOR SIMULTANEOUSLY DETECTING ABSOLUTE CONCENTRATIONS OF A PLURALITY OF ELEMENTS IN A LIQUID SAMPLE  
Disclosed herein are internal standard compositions, a plurality of calibration standards, and one or more kits for use with mass spectrometry, particularly for use with an inductively coupled...
US20180101641 SYSTEMS AND METHODS OF FRAGMENT-CENTRIC TOPOGRAPHICAL MAPPING (FCTM) TO TARGET PROTEIN-PROTEIN INTERACTIONS  
A system for identifying and evaluating a pocket of a protein includes performing a Voronoi tessellation and developing a Voronoi diagram of a surface of the protein. All alpha-spheres on the...
US20180099998 STAPHYLOCOCCUS AUREUS LEUKOCIDINS, THERAPEUTIC COMPOSITIONS, AND USES THEREOF  
Disclosed herein are isolated and purified Staphylococcus aureus bi-component leukocidin, referred to herein as LukAB, and its components LukA and LukB, antibodies specific to LukA, antibodies...
9939450 Quantifying local inflammatory activity and its use to predict disease progression and tailor treatments  
This invention relates to a method of predicting progression of an inflammatory condition in a subject, which involves providing a medium comprising hyaluronan or a fragment thereof; contacting...
9938321 Cyclic peptoid oligomers, pharmaceutical compositions and methods of using the same  
Novel peptoid oligomers are disclosed that have a formula represented by the following formula I: wherein R1 and n are as described herein. The peptoids demonstrate antimicrobial and antimalarial...
9931215 Total knee replacement implant based on normal anatomy and kinematics  
A total knee replacement prosthesis is presented whose bearing surfaces are derived from an anatomically representative femur and a modified baseline tibial surface. The contacting femoral and...
US20180085995 3D MANUFACTURING USING MULTIPLE MATERIAL DEPOSITION AND/OR FUSION SOURCES SIMULTANEOUSLY WITH SINGLE OR MULTI-FLUTE HELICAL BUILD SURFACES  
A method and apparatus to improve the speed of the free-form manufacture of complex systems uses the helical build process to 3D print or manufacture objects by using multiple material fusion...
US20180085437 COMBINATION THERAPY FOR TREATING PROTEIN DEFICIENCY DISORDERS  
This application provides methods of improving protein replacement therapy by combining protein replacement therapy with active site-specific chaperones (ASSC) to increase the stability and...
9926356 Chimeric fibroblast growth factor 19 proteins and methods of use  
The present invention relates to a chimeric protein that includes an N-terminus coupled to a C-terminus, where the N-terminus includes a portion of a paracrine fibroblast growth factor (“FGF”) and...
9926355 Chimeric fibroblast growth factor 21 proteins and methods of use  
The present invention relates to a chimeric protein that includes an N-terminus coupled to a C-terminus, where the N-terminus includes a portion of a paracrine fibroblast growth factor (“FGF”) and...
9926353 Immunotherapeutic modulation of amyloidogenic disease using non-fibrillogenic, non-amyloidogenic polymerized proteins and peptides  
The present invention is directed to polymerized products and compositions useful for the treatment and prevention of amyloid disease in a subject. The invention further relates to isolated...
US20180081997 EMBEDDED SECURITY ELEMENTS FOR DIGITAL MODELS USED IN ADDITIVE MANUFACTURING  
A method for securing a computer-aided design (CAD)-based shape to prevent shape counterfeiting by unauthorized three-dimensional (3D) printing includes creating and embedding a security element...
US20180078658 COMPOSITIONS AND METHOD FOR REDUCING SEIZURES  
Provided are compositions and methods for prophylaxis and/or therapy of disorders that involve seizures. The compositions and methods relate to a recombinant adeno-associated virus (rAAV)...
US20180078115 ENDOSCOPE RESTRAINT  
An endoscope restraining system for restraining motion of an endoscope tube includes an attachment portion configured to attach the endoscope restraining system to a surface, a flexible tube...
9921285 System, method and computer-accessible medium for highly-accelerated dynamic magnetic resonance imaging using golden-angle radial sampling and compressed sensing  
Exemplary method, system and computer-accessible medium can be provided which facilitates an acquisition of radial data, which can be continuous, with an exemplary golden-angle procedure and...
US20180071400 IMMUNOGENIC POLYPEPTIDES  
The present invention relates to isolated immunogenic polypeptides and their use. In one aspect, the isolated immunogenic polypeptide includes a scaffold polypeptide having a hairpin loop modified...
9916654 System, method and computer accessible mediums for determining neurodegeneration  
Method, system and computer-accessible medium for determining at least one of axonal loss or myelin degradation can be provided. For example, it is possible to receive data based on at least one...