Patents and Patent Applications from National Jewish Health


Matches 1 - 50 out of 302 1 2 3 4 5 6 7 >
Match Document Document Title
US20170333631 DEVICE AND METHOD TO FACILITATE PLEURODESIS FOR MANAGEMENT OF FLUID DRAINAGE  
A device, method, and system are provided for treating pleural effusion by administration of a chemical agent through a pleural catheter to achieve pleurodesis. A first embodiment includes a dual...
9820951 Pulmonary disease treatment and diagnosis based on Arhgef1  
Treatment and diagnostic methods are provided for pulmonary disease, including chronic obstructive pulmonary disease, Arhgef1, a leukocyte signaling molecule, functions normally to suppress...
US20170330320 SYSTEMS AND METHODS FOR AUTOMATIC DETECTION AND QUANTIFICATION OF PATHOLOGY USING DYNAMIC FEATURE CLASSIFICATION  
Methods, devices, and systems are provided for quantifying an extent of various pathology patterns in scanned subject images. The detection and quantification of pathology is performed...
9796961 Conditionally immortalized long-term stem cells and methods of making and using such cells  
Disclosed are methods for conditionally immortalizing stem cells, including adult and embryonic stem cells, the cells produced by such methods, therapeutic and laboratory or research methods of...
US20170191063 Targeting the Steroidogenic Pathway For Treating and/or Preventing Allergic Diseases  
The present invention relates to methods and compositions for treating and/or preventing allergic diseases or conditions by inhibiting one or more components of the steroidogenic pathway.
US20170183730 METHODS AND COMPOSITIONS FOR RISK PREDICTION, DIAGNOSIS, PROGNOSIS, AND TREATMENT OF PULMONARY DISORDERS  
The invention provides diagnostic and therapeutic targets for pulmonary disease, in particular, fibrotic lung disease. The inventors have found that a genetic variant MUC5B gene is associated with...
US20170176455 Methods of Detecting and Preventing Atopic Allergic Diseases  
The present invention is related to novel methods for identifying a population of subjects that are at risk for developing of atopic allergic diseases, and to the prevention of these allergic...
9624543 Markers for diagnosis of pulmonary inflammation and methods related thereto  
The present invention is related to the novel discovery of a number of genes that were identified as systemic markers of pulmonary inflammation. This discovery allows for development of a novel...
US20170102395 Methods for Diagnosing and Treating Subjects for Pulmonary Exacerbation  
The present invention is related to novel methods for diagnosing and treating acute pulmonary exacerbation in subjects in need thereof.
US20170096484 METHODS OF TREATING DISEASES WHICH ARE MEDIATED BY CUTANEOUS LYMPHOCYTE ANTIGEN POSITIVE CELLS  
The present invention relates to methods of treating patients suffering from itching and puritis mediated by cutaneous lymphocyte antigen positive T cell. In particular, diseases or disorders...
US20170087166 METHODS FOR TREATING AND PREVENTING ALLERGIES AND ACUTE ALLERGIC RESPONSES  
The present invention relates to methods and compositions for treating and/or preventing allergic diseases and/or conditions, as well as for preventing acute allergic responses by administering a...
9605251 Compositions, methods and uses for stimulating immune responses  
Embodiments herein report compositions, methods and uses for inducing an innate immune response in a subject. Embodiments herein also generally report compositions, methods and uses for...
US20170003300 METHODS FOR DETECTION OF RESPIRATORY DISEASES  
Disclosed are methods of identifying, predicting and treating subjects at risk for exacerbation or the presence of a respiratory disease, by detecting expression levels of one or more proteins...
9534221 Targeting the steroidogenic pathway for treating and/or preventing allergic diseases  
The present invention relates to methods and compositions for treating and/or preventing allergic diseases or conditions by inhibiting one or more components of the steroidogenic pathway.
US20160361414 Methods of Treating and Preventing Minor Histocompatibility Antigen-Mismatched Grafts  
Disclosed herein are methods of preventing and/or reducing minor histocompatibility antigen-mismatched grafts by depletion and/or inhibition of basic leucine zipper transcription factor ATF-like 3...
9505819 Genes and proteins associated with angiogenesis and uses thereof  
Disclosed is a panel of biomarkers associated with angiogenesis, and the use of such biomarkers (genes, proteins, homologues and analogs thereof) to regulate angiogenesis. Methods for identifying...
US20160312285 METHODS OF IDENTIFYING AND TREATING SUBJECTS HAVING ACUTE RESPIRATORY DISTRESS SYNDROME  
The present invention is related to novel methods for categorizing and treating subjects having Acute Respiratory Distress Syndrome (ARDS).
US20160310492 Marker for Cancer Prognosis and Methods Related Thereto  
The present invention is related to the novel discovery that HIF-2α, but not HIF-1α, selectively regulates adenosine A2A receptor in endothelial cells, thereby revealing a unique and hitherto...
US20160282363 Methods of Treating Subjects having Severe and/or Persistent Asthma  
The present invention is directed toward novel methods to treat subjects having severe and/or persistent asthma.
US20160250100 DISPOSABLE VIAL HOLDER AND METHOD TO PREVENT NEEDLE STICK INJURIES  
A vial holder is provided to protect a user's hand from needle sticks. The holder includes a handle and a shield attached to a distal end of the handle. An opening is formed in the distal end of...
US20160215344 Methods of Identifying and Treating Subjects having Inflammatory Subphenotypes of Asthma  
The present invention is directed toward novel methods to identify and treat subjects having inflammatory asthma subphenotypes.
9383374 Methods to determine susceptibility to treatment with leukotriene modifiers  
The present invention provides a method of determining the susceptibility of a subject to treatment with a leukotriene modifier by determining the subject's cysteinyl leukotriene (CysLT) level and...
US20160175431 Vaccine Composition  
Disclosed are compositions and the use of the compositions for protection against pathogens comprising an isolated internal pathogenic protein, a TLR agonist and an aluminum salt.
9346567 Disposable vial holder and method to prevent needle stick injuries  
A vial holder is provided to protect a user's hand from needle sticks. The holder includes a handle and a shield attached to a distal end of the handle. An opening is formed in the distal end of...
US20160113940 METHODS OF TREATING BIOFILMS  
A method of treating or preventing a condition caused by a biofilm in a subject is carried out by: providing a subject having, or susceptible to, a condition mediated by a biofilm produced by a...
9314479 Methods and compositions for the disruption of biofilms  
The invention relates to methods of inhibiting biofilm formation or reducing biofilms in a subject or on a device or surface by administering a charged compound such as a polyamino acid to a...
US20160101115 METHODS OF TREATING ERECTILE DYSFUNCTION  
An active agent for use in a method of, or for use in the preparation of a medicament for, treating or inhibiting the development of erectile dysfunction and/or incontinence following pelvic...
9289471 Product and process for liquefaction of mucus or sputum  
Disclosed are compositions and methods for decreasing the viscosity and/or cohesiveness of and/or increasing the liquefaction of excessively or abnormally viscous or cohesive mucus or sputum. The...
9289434 Substituted porphyrins  
The present invention relates, in general, to a method of modulating physiological and pathological processes and, in particular, to a method of modulating cellular levels of oxidants and thereby...
US20160068909 MARKERS FOR DIAGNOSIS OF PULMONARY INFLAMMATION AND METHODS RELATED THERETO  
The present invention is related to the novel discovery of a number of genes that were identified as systemic markers of pulmonary inflammation. This discovery allows for development of a novel...
US20160040129 CONDITIONALLY IMMORTALIZED LONG-TERM STEM CELLS AND METHODS OF MAKING AND USING SUCH CELLS  
Disclosed are methods for conditionally immortalizing stem cells, including adult and embryonic stem cells, the cells produced by such methods, therapeutic and laboratory or research methods of...
US20150377884 METHODS TO IDENTIFY AND TREAT SUBJECTS HAVING CORTICOSTEROID-RESISTANT INFLAMMATORY DISEASES  
The present invention is directed toward novel methods to identify as well as to treat a subject having an inflammatory disease resistant to corticosteroids.
US20150366899 Methods and Compositions for the Disruption of Biofilms  
The invention relates to methods of inhibiting biofilm formation or reducing biofilms in a subject or on a device or surface by administering a charged compound such as a polyamino acid to a...
US20150322520 Methods for Categorizing and Treating Subjects at Risk for Pulmonary Exacerbation and Disease Progression  
The present invention is related to novel methods for categorizing and treating a population of subjects that are at risk for increased pulmonary exacerbation and disease progression.
US20150322421 TREATMENT FOR AIRWAY CAST OBSTRUCTION  
The present invention is directed to methods of treatment of airway obstruction associated with fibrin-containing cast formation by administering a fibrinolytic agent.
9150831 Conditionally immortalized long-term stem cells and methods of making and using such cells  
Disclosed are methods for conditionally immortalizing stem cells, including adult and embryonic stem cells, the cells produced by such methods, therapeutic and laboratory or research methods of...
US20150240205 CONDITIONALLY IMMORTALIZED LONG-TERM STEM CELLS AND METHODS OF MAKING AND USING SUCH CELLS  
Disclosed are methods for conditionally immortalizing stem cells, including adult and embryonic stem cells, the cells produced by such methods, therapeutic and laboratory or research methods of...
US20150231150 SUBSTITUTED PORPHYRINS  
The present invention relates, in general, to a method of modulating physiological and pathological processes and, in particular, to a method of modulating cellular levels of oxidants and thereby...
US20150150891 Surfactant Lipids, Compositions Thereof, and Uses Thereof  
The invention generally relates to methods to inhibit inflammation or pathogen infection by administering at least one anionic lipid or compositions comprising at least one anionic lipid to an...
US20150089906 DISPOSABLE VIAL HOLDER AND METHOD TO PREVENT NEEDLE STICK INJURIES  
A vial holder is provided to protect a user's hand from needle sticks. The holder includes a handle and a shield attached to a distal end of the handle. An opening is formed in the distal end of...
US20150087589 GENES AND PROTEINS ASSOCIATED WITH ANGIOGENESIS AND USES THEREOF  
Disclosed is a panel of biomarkers associated with angiogenesis, and the use of such biomarkers (genes, proteins, homologues and analogs thereof) to regulate angiogenesis. Methods for identifying...
8961490 Disposable vial holder and method to prevent needle stick injuries  
A vial holder is provided to protect a user's hand from needle sticks. The holder includes a handle and a shield attached to a distal end of the handle. An opening is formed in the distal end of...
US20150051259 PRO-INFLAMMATORY MEDIATORS IN DIAGNOSIS AND TREATMENT OF PULMONARY DISEASE  
Treatment and diagnostic methods are provided for pulmonary disease, including chronic obstructive pulmonary disease. Various pro-inflammatory mediators are elevated in a model of COPD that can be...
US20150044190 PRODUCT AND PROCESS FOR LIQUEFACTION OF MUCUS OR SPUTUM  
Disclosed are compositions and methods for decreasing the viscosity and/or cohesiveness of and/or increasing the liquefaction of excessively or abnormally viscous or cohesive mucus or sputum. The...
8946202 Substituted porphyrins  
The present invention relates, in general, to a method of modulating physiological and pathological processes and, in particular, to a method of modulating cellular levels of oxidants and thereby...
US20150017227 Methods and Compositions for Treating Skin Diseases and Conditions  
Disclosed are methods and compositions for treating skin diseases or conditions with a composition containing a lipid component as an active ingredient.
US20150010492 Methods and Compositions for the Disruption of Biofilms  
The invention relates to methods of inhibiting biofilm formation or reducing biofilms in a subject or on a device or surface by administering a charged compound such as a polyamino acid to a...
US20140377310 METHODS TO TREAT ALLERGIC CONDITIONS  
Disclosed are methods to treat allergic conditions, including pulmonary and non-pulmonary conditions, in a subject by administering a composition that inhibits Pim kinase. Also disclosed are...
US20140364452 METHODS TO DETERMINE SUSCEPTIBILITY TO TREATMENT WITH LEUKOTRIENE MODIFIERS  
The present invention provides a method of determining the susceptibility of a subject to treatment with a leukotriene modifier by determining the subject's cysteinyl leukotriene (CysLT) level and...
8901167 Product and process for inhibition of biofilm development  
Disclosed are compositions and methods for the inhibition of biofilm formation or reduction of existing or developing biofilms in a patient. These methods also inhibit the aggregation of bacteria...
Matches 1 - 50 out of 302 1 2 3 4 5 6 7 >