Patents and Patent Applications from National Jewish Health


Matches 1 - 50 out of 160 1 2 3 4 >
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US20120128759 METHOD TO INHIBIT AIRWAY HYPERRESPONSIVENESS USING AEROSOLIZED T CELL RECEPTOR ANTIBODIES  
Disclosed is a method to reduce airway hyperresponsivesness in an animal by the direct delivery to the lungs of aerosolized antibodies against T cell receptors. The method is particularly useful...
8178098 Method to inhibit airway hyperresponsiveness using aerosolized T cell receptor antibodies  
Disclosed is a method to reduce airway hyperresponsivesness in an animal by the direct delivery to the lungs of aerosolized antibodies against T cell receptors. The method is particularly useful...
US20120114663 METHODS TO TREAT ALLERGIC CONDITIONS  
Disclosed are methods to treat allergic conditions, including pulmonary and non-pulmonary conditions, in a subject by administering a composition that inhibits Pim kinase. Also disclosed are...
8158107 Genes and proteins associated with angiogenesis and uses thereof  
Disclosed is a panel of biomarkers associated with angiogenesis, and the use of such biomarkers (genes, proteins, homologues and analogs thereof) to regulate angiogenesis. Methods for identifying...
8143059 Method for identification of cell growth or differentiation factors  
The present invention relates to novel immortalized precursor cell populations derived from embryonic stem cell populations and methods to produce such cell populations. Also disclosed is an assay...
US20120065611 DISPOSABLE VIAL HOLDER AND METHOD TO PREVENT NEEDLE STICK INJURIES  
A vial holder is provided to protect a user's hand from needle sticks. The holder includes a handle and a shield attached to a distal end of the handle. An opening is formed in the distal end of...
8101361 Markers for diagnosis of pulmonary inflammation and methods related thereto  
The present invention is related to the novel discovery of a number of genes that were identified as systemic markers of pulmonary inflammation. This discovery allows for development of a novel...
8058396 Cystatin C as an antagonist of TGF-β and methods related thereto  
Disclosed are Cystatin C (CysC) homologues, including CystC homologues that act as antagonists or inhibitors of transforming growth factor-β (TGF-β). Also disclosed are methods to identify CystC h...
US20110250600 MARKER FOR CANCER PROGNOSIS AND METHODS RELATED THERETO  
The present invention is related to the novel discovery that HIF-2α, but not HIF-1α, selectively regulates adenosine A2A receptor in endothelial cells, thereby revealing a unique and hitherto u...
US20110230974 AIRWAY ANCHOR SUTURE TO PREVENT AIRWAY STENT MIGRATION  
An airway stent with an integral suture anchor is used to prevent migration of the stent within the airway. The suture anchor is incorporated by percutaneous placement of a suture through the neck...
US20110217315 METHODS AND COMPOSITIONS FOR RISK PREDICTION, DIAGNOSIS, PROGNOSIS, AND TREATMENT OF PULMONARY DISORDERS  
The invention provides diagnostic and therapeutic targets for pulmonary disease, in particular, fibrotic lung disease. The inventors have found that a genetic variant MUC5B gene is associated with...
US20110212093 METHODS OF TREATING DISEASES WHICH ARE MEDIATED BY CUTANEOUS LYMPHOCYTE ANTIGEN POSITIVE CELLS  
The present invention relates to methods of treating patients suffering from itching and puritis mediated by cutaneous lymphocyte antigen positive T cell. In particular, diseases or disorders...
7999082 Anti-factor B antibodies  
Disclosed are novel inhibitors of the alternative complement pathway and particularly, novel anti-factor B antibodies. Also disclosed is the use of such inhibitors to reduce or prevent airway...
7994115 Three-dimensional structures of TALL-1 and its cognate receptors and modified proteins and methods related thereto  
Disclosed are TALL-1 and TALL-1 receptor protein homologues (agonists and antagonists) designed based on the three-dimensional structure of sTALL-1, eBCMA and eBAFF-R; agonist homologues of APRIL;...
US20110136775 Methods for Treating Injury Associated with Exposure to an Alkylating Species  
Compounds may be administered to prevent or rescue organ injury following exposure to alkylating agents, such as sulfur mustards. The compounds may be substituted metalloporphyrins.
US20110105452 Oxidant Scavengers for Treatment of Diabetes or Use in Transplantation or Induction of Immune Tolerance  
The present invention relates, in one embodiment, to a method of preventing or treating diabetes using low molecular weight antioxidants. In a further embodiment, the invention relates to a method...
US20110097327 PRODUCT AND METHOD FOR TREATMENT OF CONDITIONS ASSOCIATED WITH RECEPTOR-DESENSITIZATION  
Particular members of the multisubunit immune recognition receptor (MIRR) family of receptors, specifically, the B cell antigen receptor (BCR), the pre-B cell receptor (pre-BCR), the pro-B cell...
US20110003304 METHOD AND KIT FOR DETECTION OF AUTOIMMUNE CHRONIC URTICARIA  
Disclosed is a rapid, non-invasive and highly specific and sensitive diagnostic assay for the identification of individuals with autoimmune chronic urticaria, which makes use of CD203c, and in some...
US20110002980 VACCINES USING NUCLEIC ACID-LIPID COMPLEXES  
This invention relates to a vaccine and a method for immune activation which is effective for eliciting both a systemic, non-antigen specific immune response and a strong antigen-specific immune...
US20100279351 Method for Generation of Antibodies  
This invention generally relates to methods for the production of antibody producing cells and antibodies in protooncogene expressing animals. The invention also relates to methods for the...
7825224 Product and method for treatment of conditions associated with receptor-desensitization  
Particular members of the multisubunit immune recognition receptor (MIRR) family of receptors, specifically, the B cell antigen receptor (BCR), the pre-B cell receptor (pre-BCR), the pro-B cell...
7825089 Three-dimensional structures of TALL-1 and its cognate receptors and modified proteins and methods related thereto  
Disclosed are TALL-1 and TALL-1 receptor protein homologues (agonists and antagonists) designed based on the three-dimensional structure of sTALL-1, eBCMA and eBAFF-R; agonist homologues of APRIL;...
US20100272739 Modulation of Gamma-Delta T Cells to Regulate Airway Hyperresponsiveness  
Disclosed is a method for regulation of airway hyperresponsiveness by modulating the action of γδ T cells in a patient. Also disclosed are methods for identifying compounds that regulate airway h...
US20100267644 Cystatin C as an Antagonist of TGF-BETA and Methods Related Thereto  
Disclosed are Cystatin C (CysC) homologues, including CystC homologues that act as antagonists or inhibitors of transforming growth factor-β (TGF-β). Also disclosed are methods to identify CystC h...
US20100266600 METHODS OF USING IL-31 ANTAGONISTS IN DISEASES MEDIATED BY CUTANEOUS LYMPHOCYTE ANTIGEN POSITIVE T CELLS  
The present invention relates to predicting therapeutic response of treating patients suffering from itching and puritis mediated by cutaneous lymphocyte antigen positive T cells in atopic...
7790762 Compounds and methods for thiol-containing compound efflux and cancer treatment  
Methods for therapy of cystic fibrosis and other conditions such as cancer are provided. The methods comprise one or more agents capable of increasing thiol-containing compound transport via a...
US20100196376 METHOD FOR REDUCING ALLERGEN-INDUCED AIRWAY HYPERRESPONSIVENESS  
Disclosed is a method to reduce airway hyperresponsiveness, such as allergen-induced airway hyperresponsiveness, in a mammal by administering an agent that increases the biological activity of a...
7754705 Cationic steroid antimicrobial compositions and methods of use  
The invention provides methods for decreasing or inhibiting poxvirus infection or pathogenesis of a cell in vitro, ex vivo or in vivo, a symptom or pathology associated with poxvirus infection or...
7749958 Cystatin C as an antagonist of TGF-β and methods related thereto  
Disclosed are Cystatin C (CysC) homologues, including CystC homologues that act as antagonists or inhibitors of transforming growth factor-β (TGF-β). Also disclosed are methods to identify CystC h...
7741300 Methods of using nucleic acid vector-lipid complexes  
This invention relates to a vaccine and a method for immune activation which is effective for eliciting both a systemic, non-antigen specific immune response and a strong antigen-specific immune...
7718618 Human cathelicidin antimicrobial peptides  
Provided are peptide and peptide consensus sequences, which inhibit bacterial growth and/or viral growth and mimic the activity of LL-37, CRAMP, and/or FALL-39. The peptides are useful as...
US20090311231 PRODUCT AND PROCESS FOR LIQUEFACTION OF MUCUS OR SPUTUM  
Disclosed are compositions and methods for decreasing the viscosity and/or cohesiveness of and/or increasing the liquefaction of excessively or abnormally viscous or cohesive mucus or sputum. The...
US20090254831 YAHRZEIT SYSTEM AND METHOD  
A method of and system for providing an electronic Yahrzeit display corresponding to the current date including determining a current date, performing a search in a database storing a plurality of...
7582300 Modulation of gamma delta T cells to regulate airway hyperresponsiveness  
Disclosed is a method for regulation of airway hyperresponsiveness by modulating the action of γδ T cells in a patient. Also disclosed are methods for identifying compounds that regulate airway h...
US20090162427 VACCINES USING NUCLEIC ACID-LIPID COMPLEXES  
This invention relates to a vaccine and a method for immune activation which is effective for eliciting both a systemic, non-antigen specific immune response and a strong antigen-specific immune...
7534438 Product and process for liquefaction of mucus or sputum  
Disclosed are compositions and methods for decreasing the viscosity and/or cohesiveness of and/or increasing the liquefaction of excessively or abnormally viscous or cohesive mucus or sputum. The...
US20090093401 CYSTATIN C AS AN ANTAGONIST OF TGF-BETA AND METHODS RELATED THERETO  
Disclosed are Cystatin C (CysC) homologues, including CystC homologues that act as antagonists or inhibitors of transforming growth factor-β (TGF-β). Also disclosed are methods to identify CystC h...
7498047 Methods for treatment of thiol-containing compound deficient conditions  
Methods for therapy of cystic fibrosis and other conditions are provided. The methods comprise one or more agents capable of increasing thiol-containing compound transport via a transporter system...
7468048 Joint aspirate facilitating device  
A joint aspirate-facilitating device is provided including a flexible main panel that is secured to the joint to be aspirated. An inflatable bladder is secured to the main panel and is placed in...
US20080306000 Three-Dimensional Structures of TALL-1 and its Cognate Receptors and Modified Proteins and Methods Related Thereto  
Disclosed are TALL-1 and TALL-1 receptor protein homologues (agonists and antagonists) designed based on the three-dimensional structure of sTALL-1, eBCMA and eBAFF-R; agonist homologues of APRIL;...
US20080248025 Gamma Delta T Cells and Methods of Treatment of Interleukin-17 Related Conditions  
This invention generally relates to methods to treat conditions and diseases associated with interleukin-17 (IL-17) production. The invention also relates to methods of inhibiting γδ T cells, and p...
US20080242640 Surfactant Lipids, Compositions Thereof and Uses Thereof  
The invention generally relates to methods to inhibit inflammation or pathogen infection by administering at least one anionic lipid or compositions comprising at least one anionic lipid to an...
US20080207556 Product and Process for Inhibition of Biofilm Development  
Disclosed are compositions and methods for the inhibition of biofilm formation or reduction of existing or developing biofilms in a patient. These methods also inhibit the aggregation of bacteria...
US20080199509 Methods and Compositions for the Disruption of Biofilms  
The invention relates to methods of inhibiting biofilm formation or reducing biofilms in a subject or on a device or surface by administering a charged compound such as a polyamino acid to a...
7374934 Cell populations and methods of production thereof  
The present invention relates to novel immortalized precursor cell populations derived from embryonic stem cell populations and methods to produce such cell populations. Also disclosed is an assay...
US20080086070 Joint Aspirate Facilitating Device  
A joint aspirate-facilitating device is provided including a flexible main panel that is secured to the joint to be aspirated. An inflatable bladder is secured to the main panel and is placed in...
US20080085883 OXIDANT SCAVENGERS FOR TREATMENT OF DIABETES OR USE IN TRANSPLANTATION OR INDUCTION OF IMMUNE TOLERANCE  
The present invention relates, in one embodiment, to a method of preventing or treating diabetes using low molecular weight antioxidants. In a further embodiment, the invention relates to a method...
US20080070256 Non-Human Animal Models for B-cell Non-Hodgkin's Lymphoma and Uses Thereof  
Disclosed are non-human animal models, and preferably, rodent models, and more preferably, mouse models, of B-cell Non-Hodgkin's Lymphoma (NHL). In particular, the present invention provides animal...
US20080064103 Product and method for treatment of conditions associated with receptor-desensitization  
Particular members of the multisubunit immune recognition receptor (MIRR) family of receptors, specifically, the B cell antigen receptor (BCR), the pre-B cell receptor (pre-BCR), the pro-B cell...
US20080063629 METHOD FOR PRODUCTION OF NEUTROPHILS AND USES THEREFOR  
An in vitro method for the differentiation of functionally mature neutrophils from stem cells is disclosed. Also disclosed are methods of producing genetically modified neutrophils in vitro and...
Matches 1 - 50 out of 160 1 2 3 4 >