Patents and Patent Applications from Medical University of South Carolina


Matches 1 - 50 out of 52 1 2 >
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US20120046232 COMPOSITIONS AND METHODS FOR REDUCING RELAPSE OF ADDICTIVE BEHAVIOR  
Disclosed are methods and compositions comprising mGluR modulators and procysteine drugs. The methods and compositions can be used to treat subjects with prior addiction in order to reduce drug...
8058227 Method of treating fibrosis in a subject in need thereof comprising administering a composition comprising a CSD  
Disclosed are compositions and methods for the treatment of fibrosis. Also disclosed are methods of screening for agents that treat fibrosis.
US20110236403 TARGETING PAX2 FOR THE INDUCTION OF DEFB1-MEDIATED TUMOR IMMUNITY AND CANCER THERAPY  
Provided is a method of treating cancer in a subject by inhibiting expression of PAX2. An example of a cancer treated by the present method is prostate cancer. In the cancer treatment methods...
US20110178162 TARGETING PAX2 FOR THE INDUCTION OF DEFB1-MEDIATED TUMOR IMMUNITY AND CANCER THERAPY  
Provided is a method of treating cancer in a subject by inhibiting expression of PAX2. An example of a cancer treated by the present method is prostate cancer. In the cancer treatment methods...
US20110177100 TARGETING PAX2 FOR THE INDUCTION OF DEFB1-MEDIATED TUMOR IMMUNITY AND CANCER THERAPY  
Provided is a method of treating cancer in a subject by inhibiting expression of PAX2. An example of a cancer treated by the present method is prostate cancer. In the cancer treatment methods...
US20110177075 TARGETING PAX2 FOR THE INDUCTION OF DEFB1-MEDIATED TUMOR IMMUNITY AND CANCER THERAPY  
Provided is a method of treating cancer in a subject by inhibiting expression of PAX2. An example of a cancer treated by the present method is prostate cancer. In the cancer treatment methods...
US20110086068 Compositions and Methods for Tissue Engineering, Tissue Regeneration and Wound Healing  
In accordance with certain embodiments of the present disclosure, a kit is described. The kit includes primed living cells joined to and at least partially within a three-dimensional hydrogel...
US20110077503 Automatic MRI Quantification of Structural Body Abnormalities  
Disclosed herein are methods and systems related to the body region analysis. In some forms, the analysis relates to body region abnormalities. In some forms, the methods and systems analyze and...
US20110033516 METHODS AND COMPOSITIONS FOR BONE HEALING BY PERIOSTIN  
The present invention provides methods and compositions for increasing bone production and/or decreasing bone fracture healing time in a subject, by administering an effective amount of periostin...
US20100130432 Non-Natural Amino Acids and Neurotensin Analogues Thereof  
This invention relates to non-natural desamino amino acid compounds, methods of making, and peptides containing these compounds as their N-terminus moieties. A preferred example is neurotensin...
US20100113863 Methods and Systems for Using Transcranial Magnetic Stimulation to Enhance Cognitive Performance  
Methods and systems are provided for using transcranial magnetic stimulation (TMS) to enhance cognitive performance of at least one subject. At least one neural circuit is located in the brain of...
7462480 Stimulation of microbial dechlorination of polychorinated biphenyls with halogenated ethenes  
Disclosed is a method for the anaerobic microbial dechlorination of polychlorinated biphenyls (PCBs). Polyhalogenated ethenes are used to stimulate the growth and dechlorinating activity of PCB...
US20080227846 METHODS OF TREATING JUVENILE TYPE 1 DIABETES MELLITUS  
The present disclosure describes methods for treating or preventing Type 1 diabetes mellitus in juveniles, particularly in juveniles newly diagnosed with Type 1 diabetes. This prevention or...
US20060223774 Tissue-specific and pathogen-specific toxic agents, ribozymes, dnazymes and antisense oligonucleotides, and methods of use thereof  
The present invention relates to the discovery, identification and characterization of toxic agents which are lethal to pathogens and methods for targeting such toxic agents to a pathogen or...
US20060036152 Systems & methods for detecting deception by measuring brain activity  
Methods for determining whether the brain activity of a human subject in response to a stimulus of interest or question of interest is characteristic of a state of interest, such as a deceptive...
6946248 Compositions and methods for microbial dechlorination of polychlorinated biphenyl compounds  
Bioremediative microorganisms comprising a 16S ribosomal subunit nucleic acid sequence and useful in various methods for dechlorinating chlorinated biphenyls (PCBs), including anaerobic...
6858396 Positively charged non-natural amino acids, methods of making and using thereof in peptides  
This invention relates to positively charged non-natural amino acids, methods of making thereof, and utilization thereof in peptides.
6783946 Positively charged non-natural amino acids, methods of making thereof, and use thereof in peptides  
This invention relates to positively charged non-natural amino acids, methods of making thereof, and utilization thereof in peptides. In one embodiment, the invention relates to non-natural amino...
6747140 Tissue kallikrein gene promoter polymorphisms  
The present invention provides a method of identifying a human subject as having an increased likelihood of regulating blood pressure with dietary sodium intake, comprising determining the presence...
US20040072138 Attenuation of ischemia/reperfusion injury  
This current invention includes compositions and methods of nitric oxide synthase inhibitors to treat or reduce ischemia/reperfusion injury in a patient. More specifically, the invention relates to...
US20030157490 Methods and compositions of correlating tissue kallikrein gene promoter polymorphisms with treatment of essential hypertension  
The present invention provides a method of identifying a human subject as having an increased likelihood of regulating blood pressure with dietary sodium intake, comprising determining the presence...
US20030134266 Methods of screening for compounds that modulate blood vessel formation  
The invention provides a method of screening for agents that promote or inhibit vasculogenesis or angiogenesis. The screening methods comprise culturing mesodermal stem cells, for example,...
US20030125280 Tissue specific and target RNA-specific ribozymes as antimicrobial therapeutics against microbial pathogens  
The invention provides compositions comprising the tissue specific and target RNA-specific ribozyme(s) in either a viral delivery system or a biologic liposome preparation, wherein the viral...
6582700 Linear antigen supporting units  
The present invention concerns a synthetic construct comprising a linear core chain having two or more side chains pending directly from different points on the linear core chain. Each of the side...
6566330 Positively charged non-natural amino acids, methods of making and using thereof in peptides  
This invention relates to positively charged non-natural amino acids, methods of making thereof, and utilization thereof in peptides.
US20030092651 Tissue-specific and target RNA-specific ribozymes  
The present invention relates to multi-ribozymes and their use to target RNA in a tissue-specific, target RNA-specific, or pathogen-specific manner for the treatment of cancers, proliferative...
6511800 Methods of treating nitric oxide and cytokine mediated disorders  
The current invention discloses novel methods for the inhibition of inducible nitric oxide synthesis (iNOS) and the production of NO. Methods of inhibiting the induction of proinflammatory...
US20020137730 Positively charged non-natural amino acids, methods of making and using thereof in peptides  
This invention relates to positively charged non-natural amino acids, methods of making thereof, and utilization thereof in peptides.
US20020068701 Positively charged non-natural amino acids, methods of making thereof, and use thereof in peptides  
This invention relates to positively charged non-natural amino acids, methods of making thereof, and utilization thereof in peptides. In one embodiment, the invention relates to non-natural amino...
6376182 Methods and compositions for correlating tissue kallikrein gene promoter polymorphisms with treatment of essential hypertension  
The present invention provides a method of identifying a human subject as having an increased likelihood of regulating blood pressure with dietary sodium intake, comprising determining the presence...
6358922 Positively charged non-natural amino acids, methods of making thereof, and use thereof in peptides  
This invention relates to positively charged non-natural amino acids, methods of making thereof, and utilization thereof in peptides. In one embodiment, the invention relates to non-natural amino...
6103528 Reversible gelling culture media for in-vitro cell culture in three-dimensional matrices  
A gelling cell culture medium useful for forming a three dimensional matrix for cell culture in vitro is prepared by copolymerizing an acrylamide derivative with a hydrophilic comonomer to form a...
6063375 Semiallogeneic cell hybrids and related methods for treating cancer  
An isolated cell having the characteristics of the cell line designated FO-1 #12 is provided. The cell FO-1 #12 is characterized as being β2 -microglobulin-deficient, neomycin-resistant and ...
6057095 Screening procedure for inhibitors of HIV Rev function  
This invention provides a method of screening for inhibitors of HIV Rev function, comprising introducing into a cell a nucleic acid construct comprising a reporter gene positioned in the construct...
6043218 Positively charged non-natural amino acids, methods of making thereof, and use thereof in peptides  
This invention relates to positively charged non-natural amino acids, methods of making thereof, and utilization thereof in peptides. In one embodiment, the invention relates to non-natural amino...
6037129 Multi-marker RT-PCR panel for detecting metastatic breast cancer  
A method of detecting the metastasis of primary breast cancer to a lymph node is provided, comprising detecting, in lymph node tissue, the presence of a nucleic acid of c-myc, PIP or keratin-19....
5945684 Computer controlled collimator changer  
An apparatus controls a stereotactic radiosurgery dose applied to an object being treated by a linear accelerator mounted on a gantry. The linear accelerator is capable of generating a beam having...
5916869 Method of treating birds in ovo  
Methods are disclosed for administering Peptide YY (PYY) receptor agonists to birds in ovo to promote altricial development of the intestinal tract of neonatal birds. Enhanced altricial development...
5891456 Glyceryl monosterate based biodegradable implants for site-specific delivery of drugs  
A method to administer a drug locally to a subject in which biodegradable dosage forms that contain the drug are implanted at a localized site beneath the skin of the subject whereupon the dosage...
5877215 Method of treating neoplastic cells with prostaglandin and radiation treatment or prostaglandin and platinum-based anti-tumor agents  
The invention is directed to a method of increasing ionizing radiation's cytotoxic effects on a neoplasm in a subject by increasing the neoplasm's sensitivity to ionizing radiation, comprising...
5830434 Methods of treating non-insulin dependent diabetes mellitus with pancreatic polypeptide  
The present invention provides a method of treating NIDDM in a patient diagnosed with NIDDM by administering to the patient a compound in a pharmaceutically acceptable carrier that reduces hepatic...
5824519 Tissue-specific and target RNA-specific ribozymes  
The invention provides tissue-specific and target RNA-specific ribozymes. These ribozymes can be used to destroy target-specific neoplasms and to treat viral infections, among other uses. The...
5811395 Relaxin analogs and derivatives methods and uses thereof  
The present invention relates to a relaxin analogs and derivatives, and uses thereof. The present invention further relates to compositions comprising a relaxin analogs and derivatives, and relaxin...
5764339 Compressive force-activated variable focus lens and method of making the same  
A variable focus contact lens, has a body with a first half and an opposite second half. The body also has a first peripheral surface, an opposite second peripheral surface and an associated focal...
5645558 Anatomically shaped vasoocclusive device and method of making the same  
This invention is an occlusive device for inserting into body cavities or vesicles. More particularly, it is a vasoocclusive device which, as used, is in the approximate shape of an anatomical...
5525347 Composition and methods for treating performance anxiety  
The invention provides a pharmaceutical composition for treating performance anxiety and social phobia comprising a therapeutic amount for the treatment of a patient of a β-adrenergic receptor ...
5458601 Adjustable ligament anchor  
The invention provides an adjustable ligament anchor for attaching a ligament to a bone. The ligament anchor comprises a housing having an exterior surface, an interior surface, an intra-articular...
5428660 Portable medical panoramic radiographic device  
A portable, lightweight medical radiographic device having an articulated support is described. The device includes a base, an elongated supporting structure having multiple sections interconnected...
5334369 Platelet receptor antagonists useful in detecting intravascular platelet aggregation  
This invention provides novel compounds used in a method of determining platelet deposition. These compounds include 123 I-SAP and analogues. Also provided is a method of determining platelet...
4895833 Liver lactogenic factor  
The present invention relates to liver lactogenic factor and to its isolation, purification and characterization. The liver lactogenic factor of the present invention is useful to increase mil...
Matches 1 - 50 out of 52 1 2 >