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8163496 |
Methods and kits for measuring von Willebrand factor
Methods and kits for measuring levels of von Willebrand factor function in a sample without using a platelet aggregation agonist, such as ristocetin, comprising recombinant glycoprotein Ibα having ...
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8121361 |
Motion tracking system for real time adaptive imaging and spectroscopy
Current MRI technologies require subjects to remain largely motionless for achieving high quality magnetic resonance (MR) scans, typically for 5-10 minutes at a time. However, lying absolutely...
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8046077 |
Selective neuromodulation using energy-efficient waveforms
Methods of selective neuromodulation in a live mammalian subject, such as a human patient. The method comprises applying an electrical signal to a target site in the nervous system, such as the...
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US20110091410 |
Engineered CXCL12 Alpha Locked Dimer Polypeptide
The present invention provides a novel CXCL12-α2 locked dimer polypeptide, pharmaceutical compositions thereof, and methods of using said dimer in the treatment of cancer, inflammatory disorders, ...
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7923016 |
Engineered CXCL12 α locked dimer polypeptide
The present invention provides a novel CXCL12-α2 locked dimer polypeptide, pharmaceutical compositions thereof, and methods of using said dimer in the treatment of cancer, inflammatory disorders, ...
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US20110059922 |
MITOCHONDRIA TARGETED CATIONIC ANTI-OXIDANT COMPOUNDS FOR PREVENTION, THERAPY OR TREATMENT OF HYPER-PROLIFERATIVE DISEASE, NEOPLASIAS AND CANCERS
The inventions disclosed include methods of treating cancers and related neoplasias, especially prostate cancer, with pharmaceutically acceptable salts comprising lipophilic cation moieties linked...
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7887783 |
99mTc-labeled 19 amino acid containing peptide for use as phosphatidylethanolamine binding molecular probe and radiopharmaceutical
With only 19 amino acids, Duramycin is the smallest known polypeptide that has a defined 3-dimensional binding structure. Duramycin binds Phosphatidylethanolamine (PtdE) at a 1:1 ratio with high...
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US20100197580 |
PARSTATIN PEPTIDES AND USES THEREOF
The invention provides parstatin peptides, particularly a mammalian parstatin peptide including amino acids 1-26 of full length mammalian parstatin, preferably a human parstatin. The invention...
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7744590 |
Red to near-infrared photobiomodulation treatment of the visual system in visual system disease or injury
A method of treating visual system disease is disclosed. One embodiment comprises the steps of (a) exposing a component of a patient's visual system to light treatment, wherein the light treatment...
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7690057 |
Folding frame motorized prone cart
A prone cart for carrying a patient has a frame, a pair of independently powered and suspended drive wheels located centrally off the frame and an articuable body support having relatively moveable...
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US20100049276 |
Clinician programmer system and method for calculating volumes of activation for monopolar and bipolar electrode configurations
A system and method for providing a volume of activation (VOA) of a stimulation electrode leadwire may include a processor that calculates a VOA for each of a plurality of sets of parameter...
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D606910 |
Prone cart
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US20090305984 |
Engineered CXCL 12 alpha locked dimer polypeptide
The present invention provides a novel CXCL12-α2 locked dimer polypeptide, pharmaceutical compositions thereof, and methods of using said dimer in the treatment of cancer, inflammatory disorders, ...
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US20090214437 |
In Vivo Mitochondrial Labeling Using Positively-Charged Nitroxide Enhanced and Gadolinium Chelate Enhanced Magnetic Resonance Imaging
A system and method for acquiring MR imaging data from a subject includes administering positively-charged nitroxides or gadolinium chelates for in vivo mitochondrial labeling, acquiring MR imaging...
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US20090105145 |
Method of Diagnosing and Treating Colon Cancer
The invention provides a method of diagnosing carcinoma in a patient, the method comprising providing a sample of colorectal cells from a human patient and analyzing the sample for CXCL12...
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6617355 |
Treating asthma by preventing and/or accomodating S-nitrosothiol breakdown
Asthma is ameliorated, and mild or moderate asthma is prevented from progressing to more severe asthma by administering agents which prevent and/or accommodate for S-nitrosothiol breakdown.
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6608110 |
Manipulating nitrosative stress to kill pathologic microbes, pathologic helminths and pathologically proliferating cells or to upregulate nitrosative stress defenses
Mammals are treated for infections or for conditions associated with pathologically proliferating mammalian cell growth by administration of a manipulator of nitrosative stress to selectively kill...
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6359004 |
Manipulating nitrosative stress to upregulate nitrosative stress defenses
Mammals are treated for infections or for conditions associated with pathologically proliferating mammalian cell growth (for example, certain cancers, restenosis, benign prostatic hypertrophy) by...
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6180824 |
Manipulating nitrosative stress to kill pathologic microbes, pathologic helminths and pathologically, proliferating cells or to upregulate nitrosative stress defenses
Mammals are treated for infection or for conditions associated with pathologically proliferating mammalian cell growth (for example, certain cancers, restenosis, benign prostatic hypertrophy) by...
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6127420 |
L-N5 -(1-imino-3-alkenyl) ornithine and related compounds and use thereof
Selective and irreversible inhibitors of neuronal isoform of nitric oxide synthase catalyzed production of nitric oxide are L-ornithine or L-lysine derivatives having the formula ##STR1## wherein Q...
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6103722 |
Ischemic preconditioning
Methods and pharmaceutical compositions of matter are disclosed and claimed relating to cardioprotective effect mediated by delta (δ) opioid receptor agonists or more specifically delta-1 ...
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6057367 |
Manipulating nitrosative stress to kill pathologic microbes, pathologic helminths and pathologically proliferating cells or to upregulate nitrosative stress defenses
Mammals are treated for infections or for conditions associated with pathologically proliferating mammalian cell growth (for example, certain cancers, restenosis, benign prostatic hypertrophy) by...
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5827750 |
Human virus associated with chronic fatigue immune deficiency syndrome and assay therefore
A method for the detection of the presence or absence of antibodies which bind to antigens of an NMA virus indicative of Chronic Fatigue Immune Deficiency Syndrome is disclosed. This method...
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5723448 |
Preventing conversion of citrulline to argininosuccinate to limit pathological nitric oxide overproduction
Administration of argininosuccinate synthetase activity reducing agents, e.g., argininosuccinate synthetase induction blocking agents (e.g., antibiotics that bind to DNA sequences present in the...
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5663364 |
Heme binding compounds and use thereof
Inhibitors of nitric oxide formation from arginine useful for treating hypotension, inflammation, stroke and to restore vascular contractile sensitivity to the effects of α1 adrenergic agonists ...
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5545625 |
Preventing conversion of citrulline to argininosuccinate to limit pathological nitric oxide overproduction
Administration of argininosuccinate synthetase activity reducing agents, e.g., argininosuccinate synthetase induction blocking agents (e.g., antibiotics that bind to DNA sequences present in the...
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5545550 |
Human virus associated with chronic fatigue immune deficiency syndrome and assay therefore
A method for the detection of the presence or absence of antibodies which bind to antigens of an NMA virus Deficiency is disclosed. This method comprises contacting a solution containing antigens...
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5476871 |
Method for the treatment of hypotension induced by a cytokine or bacterial endotoxin using s-alkyl- isothioureido-amino acids
Inhibitors of nitric oxide formation from arginine useful for treating hypotension, inflammation, stroke and to restore vascular contractile sensitivity to the effects of α1 -adrenergic agonists ...
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5464858 |
Heme binding compounds and use thereof
Inhibitors of nitric oxide formation from arginine useful for treating hypotension, inflammation, stroke and to restore vascular contractile sensitivity to the effects of α1 adrenergic agonists ...
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5424447 |
Heme binding compounds and use thereof
Inhibitors of nitric oxide formation from arginine useful for treating hypotension, inflammation, stroke and to restore vascular contractile sensitivity to the effects of α1 adrenergic agonists ...
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5418192 |
Production of IFN using DA15 peptide
An in vitro method for the production of interferon is set forth. The method involves the culture of monocytes with a new DA15 peptide produced in Daudi cell lines in response to stimulation with...
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5364881 |
S-alkyl-isothioureido-amino acids and use thereof
Inhibitors of nitric oxide formation from arginine useful for treating hypotension, inflammation, stroke and to restore vascular contractile sensitivity to the effects of α1 -adrenergic agonists ...
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5306303 |
Bone induction method
A method of inducing bone growth in a living animal consists of implanting in the soft tissue or bone of the animal a bone morphogenetic protein-free, ceramic consisting of a calcium phosphate...
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5039483 |
Antiprotozoan method
A method of treating a body fluid so as to inactivate protozoa in said fluid comprises mixing the body fluid with an effective amount of a photosensitizing agent which will bind to cell-free...
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4915683 |
Antiviral method, agents and apparatus
A method of treating a body fluid which is to be infused so as to inactivate any enveloped viruses in said fluid comprises mixing the body fluid with an effective amount of a photosensitizing agent...
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4792564 |
Method of treatment and prevention of cerebral vasospasms
A method is disclosed for preventing or treating cerebral vasospasms such as those which usually follow subarachnoid hemorrhage. The method comprises administering to the animal a safe and...
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4788429 |
Device and method for measuring bone mineral mass
An attachment for a scintillation camera to enable the camera to be used for measurement of bone mineral mass includes a grid holder adapted to be attached to the camera, a grid mounted on the grid...
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4775625 |
Inactivating enveloped viruses with a merocyanine dye
A method of inactivating viruses comprises bringing the viruses into contact with an effective amount of a photosensitizing agent which will bind to the viruses and/or virus infected cells, and...
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4772691 |
Chemically cleavable nucleotides
Novel biotinylated nucleotides have a chemically cleavable linker arm between a biotin and an organic basic group. They are useful in a method of isolating target macromolecules from crude...
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4728796 |
Method for ionization of polymers
A method for the ionization of polymers which comprises forming a thick layer of the polymer on a probe tip and then ionizing the polymer in a vacuum with laser irradiation. In a preferred...
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4724389 |
Loop-gap resonator for localized NMR imaging
A local probe for use in nuclear magnetic resonance imaging includes a pair of loop-gap resonators which are connected together and positioned adjacent a region of interest. FID signals produced in...
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4720459 |
Myelomas for producing human/human hybridomas
Human myeloma fusing lines and human/human hybridomas produced therefrom are disclosed. In one embodiment, the myeloma cell line is HAT sensitive, does not secrete detectable levels of Epstein-Barr...
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4635643 |
Assay method for the in vivo quantitative determination of mineral content in bone
An in vivo assay for quantifying the mineral content of bone comprises placing living bone into or adjacent to the coil of a nuclear magnetic resonance (NMR) spectrometer, recording a 31 P NMR...
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4623835 |
Web thickness sensor using loop-gap resonator
The thickness of a web is measured by passing the web through the gaps of a loop-gap resonator. Changes in web thickness alter the resonant frequency of the resonator which is detected by a control...
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4613818 |
Nuclear magnetic resonance blood flowmeter
Blood flow in human limbs is measured non-invasively by a nuclear magnetic resonance blood flowmeter which includes a pair of polarizing magnets whose fields are stabilized by electromagnets in...
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4593248 |
Oxymeter
An ESR spectrometer is employed to measure the oxygen concentration in a sample material. Electron paramagnetic resonance is produced in a free radical mixed with a standard material of known...
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4552145 |
Nerve identification method
A method of identifying the matching nerve fascicles in proximal and distal nerve stumps for reanastomosis comprises histochemically making a first visible image of the pattern of carbonic...
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4510450 |
Apparatus and assay method for the quantitative determination of mineral content in bone
An assay method for the quantitative determination of the mineral content of bone comprises using proton decoupling and magic angle sample spinning techniques to record well resolved 31 P nuclear...
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4504788 |
Enclosed loop-gap resonator
The ends of a loop-gap resonator are extended along a closed path to define an enclosed chamber with a gap extending along its length. A lumped circuit resonator is formed and the magnetic field is...
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4480239 |
Loop-gap resonator network
A lumped circuit loop-gap resonator is formed by a plurality of openings formed through a block of material. The openings form inductive loop elements and these are interconnected in a variety of...
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