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US20090062379 |
COMPOSITIONS AND METHODS FOR TREATING IMMUNE DISORDERS
Green tea polyphenol compositions and methods of their use are provided. Certain aspects provide methods for modulating expression of one or more autoantigens using the disclosed green tea...
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US20090035285 |
Compositions and Methods for Enrichment of Neural Stem Cells Using Ceramide Analogs
The present invention provides compositions and methods for human neural cell production. More particularly, the present invention provides cellular differentiation methods employing amphiphilic...
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7465448 |
Chemokine receptor antagonists as therapeutic agents
The present invention provides methods and compositions to reduce immune tolerance at specific sites. In one aspect, the present invention comprises methods and compositions to reduce...
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7445931 |
Compositions and methods for enrichment of neural stem cells using ceramide analogs
The present invention provides compositions and methods for human neural cell production. More particularly, the present invention provides cellular differentiation methods employing amphiphilic...
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US20080241140 |
GENE AMPLIFICATION OF COACTIVATOR COAA AND USES THEREOF
It has been discovered that amplifications in the gene coactivator activator (CoAA) blocks stem cell differentiation and induces cancer stem cells. One embodiment provides compositions and methods...
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US20080176956 |
Modified Green Tea Polyphenol Formulations
Modified green tea polyphenols and methods of their use are provided. One aspect provides compounds and compositions containing green tea polyphenols with one on more ester-linked fatty acids.
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US20080153889 |
Compositions and Methods for the Treatment of Renal and Cardiovascular Disease
Derivative compounds of 11-nonyloxy-undec-8(Z)-eonic acid that mimic epoxide metabolites are provided. Also provided are compositions comprising a therapeutically effective amount of the derivative...
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US20080146663 |
Compositions and Methods for the Treatment of Renal and Cardiovascular Disease
Derivative compounds of 11-nonyloxy-undec-8(Z)-eonic acid that mimic epoxide metabolites are provided. Also provided are compositions comprising a therapeutically effective amount of the derivative...
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US20080131836 |
USE OF INTEGRATING SPHERE TECHNOLOGY TO PROVIDE UNIFORM, HIGH-INTENSITY LIGHT, AND WAVELENGTH MIXING FROM LIGHT EMITTING DIODES
An illumination device including an integrating sphere and at least one light source. The integrating sphere is hollow and houses the at least one light source in it. The light source can be...
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US20080131453 |
Campylobacter Jejuni Outer Membrane Protein Immunogenic Composition
The field of this invention is the development of therapeutic agents having immunogenic efficacy against Campylobacter. The present invention is directed to a method of producing monoclonal...
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US20080077439 |
AUTOMATED MEDICATION CALENDAR
A calendar-format medication instruction sheet is produced when a pharmacy processes a patient's prescription. The sheet can bear icons or photographic images of the medications that the patient is...
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7259180 |
Methods and compositions for treatment of macular and retinal disease
The present invention describes linking a therapeutic agent to a compound which is known to be naturally concentrated in a tissue affected by, or that is causing, a disease, to create a prodrug for...
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US20070162119 |
TYMPANIC MEMBRANE PROSTHESIS AND A TOOL FOR MANUFACTURING THE PROSTHESIS
A prefabricated tympanic membrane prosthesis includes a piece of collagen sheet processed with a diluted solution of formalin. The piece of collagen sheet is molded on a forming surface of a tool...
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7220851 |
Nucleic acid encoding calcyon, a D-1 like dopamine receptor activity modifying protein
A number of cDNA clones whose products may interact with D1 receptors in vivo were identified. One of the clones, P24, was characterized further. P24 is localized in dendrites and spines of...
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US20070077234 |
Regulation of T cell-mediated immunity by tryptophan
A mechanism of macrophage-induced T cell suppression is the selective elimination of tryptophan and/or increase in one or more tryptophan metabolites within the local macrophage microenvironment....
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US20070077224 |
Regulation of T cell-mediated immunity by tryptophan
A mechanism of macrophage-induced T cell suppression is the selective elimination of tryptophan and/or increase in one or more tryptophan metabolites within the local macrophage microenvironment....
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7173119 |
SUMO4 gene and methods of use for type 1 diabetes
Novel nucleic acids associated with Type 1 diabetes. Also provided are polypeptides encoded by the nucleic acids associated with T1D. The invention also provides methods for facilitating the...
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7160539 |
Regulation of T cell-mediated immunity by tryptophan
A mechanism of macrophage-induced T cell suppression is the selective elimination of tryptophan and/or increase in one or more tryptophan metabolites within the local macrophage microenvironment...
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US20060148744 |
Use of cis-epoxyeicosantrienoic acids and inhibitors of soluble epoxide hydrolase to reduce damage from stroke
The invention provides uses and methods for reducing brain damage from stroke. The uses comprise the use of an inhibitor of soluble epoxide hydrolase (sEH) for the manufacture of a medicament to...
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7067261 |
Methods and compositions for treatment of central nervous system disorders
The invention provides methods of screening for substances having an effect on a nicotine receptor by contacting a cell having a nicotine receptor with a test substance; and determining any...
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6988893 |
Disposable photographic cheek retraction apparatus and method of using the same
In an exemplary embodiment in accordance with the present invention, a disposable dental appliance and method of use is provided. In particular, a cheek retraction apparatus is provided, which is...
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US20050227993 |
Novel analogs of choline for neuroprotection and cognitive enhancement in neurodegenerative disorders
The present invention relates to novel analogs of choline and methods of use or treatment of neurodegenerative disorders and/or conditions such as Parkinson's disease, Huntington disease,...
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US20050186289 |
Regulation of T cell-mediated immunity by D isomers of inhibitors of indoleamine-2,3-dioxygenase
The present invention provides improved treatment methods by the administration of the non-physiologic D-isomer of an IDO inhibitor.
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US20050095240 |
NaCT as a target for lifespan expansion and weight reduction
The present invention provides the identification and characterization of a novel transmembrane transporter, a Na+-coupled citrate transporter (“NaCT”). Isolated polynucleotides encoding the tra...
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6881738 |
Analogs of choline for neuroprotection and cognitive enhancement in neurodegenerative disorders
The present invention relates to novel analogs of choline and methods of use or treatment of neurodegenerative disorders and/or conditions such as Parkinson's disease, Huntington disease,...
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6878531 |
Method for multiple site-directed mutagenesis
The present invention provides a simple and rapid method for site-directed mutagenesis of more than, for example, 10 sites simultaneously with up to 100% efficiency. The method uses two terminal...
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US20040234623 |
Use of inhibitors of indoleamine-2,3-dioxygenase in combination with other therapeutic modalities
The present invention provides improved treatment methods by the administration of both an inhibitor of indoleamine-2,3-dioxygenase in addition to the administration of an additional therapeutic...
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US20040191842 |
Chemopreventive and therapeutic aspects of polyphenolic compositions and assays
The present invention includes chemopreventive and therapeutic methods based on the administration of polyphenolic compositions, including the polyphenolic compositions found in green tea. The...
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6773890 |
Screen for risk for gastric adenocarcinoma
It has been determined that a specific metaplastic lineage that contains immunoreactivity for a trefoil polypeptide, spasmolytic peptide, is associated with and gives rise to the vast majority of...
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US20040147475 |
Composition and method for in vivo and in vitro attenuation of gene expression using double stranded RNA
Introduction of double stranded RNA into cells, cell culture, organs and tissue, and whole organisms, particularly vertebrates, specifically attenuates gene expression.
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US20020178461 |
Transgenic fish with tissue-specific expression
Disclosed are transgenic fish, and a method of making transgenic fish, which express transgenes in stable and predictable tissue- or developmentally-specific patterns. The transgenic fish contain...
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6482416 |
Regulation of T cell-mediated immunity by tryptophan
A mechanism of macrophage-induced T cell suppression is the selective elimination of tryptophan and/or increase in one or more tryptophan metabolites within the local macrophage microenvironment...
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US20020155104 |
Regulation of T cell-mediated immunity by tryptophan
A mechanism of macrophage-induced T cell suppression is the selective elimination of tryptophan and/or increase in one or more tryptophan metabolites within the local macrophage microenvironment...
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6469141 |
D1-like dopamine receptor activity modifying protein
A number of cDNA clones whose products may interact with D1 receptors in vivo were identified. One of the clones, P24, was characterized further. P24 is localized in dendrites and spines of...
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6455609 |
Fluoride-releasing amalgam dental restorative material
A fluoride-releasing dental amalgam composition for a tooth restoration comprising a dental amalgam alloy material and an fluoride-containing, the glass particulate powder component of a...
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6451840 |
Regulation of T cell-mediated immunity by tryptophan
A mechanism of macrophage-induced T cell suppression is the selective elimination of tryptophan and/or increase in one or more tryptophan metabolites within the local macrophage microenvironment...
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6441158 |
Oligomers that bind to ku protein
Disclosed are oligomers that bind Ku protein. These oligomers are useful for inhibiting activation of DNA-PK, treating certain forms of autoimmune disease, detection and purification of Ku protein,...
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6440398 |
Fluoride-releasing amalgam dental restorative material
A fluoride-releasing dental amalgam composition for a tooth restoration comprising a dental amalgam alloy material and an fluoride-containing, the glass particulate powder component of a...
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US20020114784 |
Composition and method for in vivo and in vitro attenuation of gene expression using double stranded RNA
Introduction of double stranded RNA into cells, cell culture, organs and tissues, and whole organisms, particularly vertebrates, specifically attenuates gene expression.
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6395876 |
High-affinity tryptophan transporter
A high affinity and extremely selective tryptophan transport system present in human monocyte-derived macrophages is disclosed. Human monocyte-derived macrophages include two distinct transporters,...
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6395549 |
Long terminal repeat, enhancer, and insulator sequences for use in recombinant vectors
Disclosed are an enhancer, insulator, and promoter from the HS5 region in the 5′ boundary area of the locus control region of human β-like globin genes. These transcription control sequences can be...
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6391281 |
Fluorescent agent for the identification of tooth dentin
A method of topically applying a fluorescing agent to a cut tooth, cut dental restorative material or dentin surface to distinguish between cut tooth or dentin and existing aesthetic restoration...
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6380458 |
Cell-lineage specific expression in transgenic zebrafish
Disclosed are transgenic fish, and a method of making transgenic fish, which express transgenes in stable and predictable tissue- or developmentally-specific patterns. The transgenic fish contain...
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US20020028856 |
Fluoride-releasing amalgam dental restorative material
A fluoride-releasing dental amalgam composition for a tooth restoration comprising a dental amalgam alloy material and an fluoride-containing, the glass particulate powder component of a...
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US20010001040 |
Regulation of T cell-mediated immunity by tryptophan
A mechanism of macrophage-induced T cell suppression is the selective elimination of tryptophan and/or increase in one or more tryptophan metabolites within the local macrophage microenvironment...
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6107048 |
Method of detecting and grading dysplasia in epithelial tissue
A method of detecting dysplastic regions within epithelial tissue samples is sensitive enough to detect and distinguish between low grade and high grade dysplastic regions. The method uses probes...
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6096303 |
Method to enhance treatment of cystic tumors
It has been discovered that cells such as genetically engineered fibroblasts and keratinocytes can be cultured in the cyst fluid of encapsulated tumors. This provides a means for proliferating...
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5488954 |
Ultrasonic transducer and method for using same
An improved ultrasonic transducer fabricated on a silicon base has a piezoelectric layer of polyvinylidene fluoride-trfluroethylene copolymer. The piezoelectric layer is sandwiched between two...
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4792520 |
Methods and kits for identifying mutagenic agents and molecular mutations in DNA in mammalian cells
A new and improved cell assay has been developed for mutagens and potential carcinogens to precisely identify the predominant type of mutation(s) each such compound induces in the DNA of cells. The...
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4461619 |
Method of predicting biological activity of compounds by nucleic acid models
A method for determining the relationship of chemical structure to biological activity based on the topology and physiochemical properties of "cavities" or "artificial constructs" constructed from...
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