Patents and Patent Applications from Massachusetts Institute of Technology MIT


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US20120130025 CHARGED POLYMERS AND THEIR USES IN ELECTRONIC DEVICES  
The present invention generally relates to compositions and methods comprising charged polymers. The compositions can be used in a variety of applications, for example, in photovoltaic cells,...
US20120129726 SUBCELLULAR IN VIVO TIME-LAPSE IMAGING AND SURGERY OF C. ELEGANS IN STANDARD MULTIWELL PLATES  
High-content time-lapse assays on whole animals require their repeated immobilization for high-resolution imaging and manipulation. Here, we present a simple, rapid, and minimally invasive method...
US20120128958 SILICA AEROGELS AND THEIR PREPARATION  
Silica aerogels with improved properties are disclosed together with methods for synthesizing such aerogels. The improved properties include lower thermal conductivity (better insulating capacity),...
US20120128350 BALANCED BYPASS CIRCULATORS AND FOLDED UNIVERSALLY-BALANCED INTERFEROMETERS  
The invention generally relates, in one aspect, to an interferometer system. The interferometer system includes a splitter/combiner element (SCE), a first bi-directional optical path, and a second...
US20120126807 TRANSPORT AND DETECTION OF SUPERPARAMAGNETIC PARTICLES BY NANOWIRE  
An apparatus, method and computer-readable medium configured to transport a constituent of fluid sample that binds to a functionalized magnetic particle. The apparatus includes a substrate...
US20120126726 Compact Cold, Weak-Focusing, Superconducting Cyclotron  
A compact, cold, weak-focusing superconducting cyclotron can include at least two superconducting coils on opposite sides of a median acceleration plane. A magnetic yoke surrounds the coils and...
8185551 Disk-resident streaming dictionary  
A method, apparatus and computer program product for storing data in a disk storage system is presented. A dictionary data structure is defined and stored on the disk storage system. Key-value...
8182804 Engineered enzymatically active bacteriophages and methods of uses thereof  
The present invention provides engineered bacteriophages that express at least one biofilm degrading enzyme on their surface and uses thereof for degrading bacterial biofilms. The invention also...
8182464 Method for intravesical drug delivery  
Implant devices for intravesical administration and local drug delivery. The device has a body which includes a hollow tube formed of a biocompatible material; at least one reservoir in the tube...
US20120124214 Method and Apparatus for Distributing Requests Among a Plurality of Resources  
The invention relates to an apparatus for responding to data requests made by a client. The apparatus includes an input receiving a first data request that includes a sequence of nodes...
US20120123519 TUBULAR SILK COMPOSITIONS AND METHODS OF USE THEREOF  
Described are tubular silk fibroin compositions and methods for their manufacture and use. Tubular compositions as described herein can be produced in a range of high burst strengths, can easily be...
US20120123508 Methods and apparatus for wireless control of biological tissue  
In exemplary implementations of this present invention, a supercapacitor-based electronic device delivers high currents to an array of implantable light sources or electrodes. The device receives...
US20120121193 IMAGE COMPARISON AND PROCESSING  
Method and systems for search and retrieval of images with an image processing system is disclosed. With an input interface, selection of a plurality of images to use in a search query is accepted....
US20120120496 A PASSIVE LOUVER-BASED DAYLIGHTING SYSTEM  
A daylighting system for use in a building including a louver array having a first longitudinal element, and a second longitudinal element spaced therefrom. At least one of the first and second...
US20120118063 APPARATUS AND METHOD FOR MEASURING BUOYANT MASS AND DEFORMABILITY OF SINGLE CELLS  
Method for determining buoyant mass and deformability of a cell. The method includes introducing the cell into a suspended microchannel resonator that includes a constriction near a distal location...
8179296 Digital readout method and apparatus  
Autonomously operating analog to digital converters are formed into a two dimensional array. The array may incorporate digital signal processing functionality. Such an array is particularly...
US20120117170 SYSTEM AND METHOD FOR PROVIDING A GEO-REFERENCED VIRTUAL COLLABORATIVE ENVIRONMENT  
A system for providing an image-referenced virtual collaborative environment contains a server in communication with at least a first client device and a second client device, wherein the server...
US20120116094 COMPOSITIONS COMPRISING AND METHODS FOR FORMING FUNCTIONALIZED CARBON-BASED NANOSTRUCTURES  
The present invention generally relates to compositions comprising and methods for forming functionalized carbon-based nanostructures.
US20120114081 Architectures For Universal Or Software Radio  
A system and technique for providing to flexible, programmable frequency estimators and spectrum analyzers that can operate over extremely large bandwidths and yet provide high spectral resolution...
US20120112152 ELECTRONICALLY CONTROLLED SQUISHABLE COMPOSITE SWITCH  
A method and apparatus for making analog and digital electronics which includes a composite including a squishable material doped with conductive particles. A microelectromechanical systems (MEMS)...
8174181 Quantum dot white and colored light-emitting devices  
A light-emitting device comprising a population of quantum dots (QDs) embedded in a host matrix and a primary light source which causes the QDs to emit secondary light and a method of making such a...
8173384 Methods for analyzing or processing a heparin sample  
The invention relates to methods and products for analyzing or processing a heparin sample. In one embodiment, the methods comprise contacting the sample with heparinase I, heparinase II and...
8173010 Method of dry reforming a reactant gas with intermetallic catalyst  
The invention relates to materials used as electrodes and/or catalysts, as well as methods associated with the same. The materials may comprise an alloy or intermetallic compound of a transition...
8172790 Needle-free injector device with autoloading capability  
A needle-free transdermal transport device includes a chamber (900) for holding the substance to be injected, a nozzle (910) in fluid communication with the chamber, and a drug reservoir (950) for...
8172784 Compositions, methods, and devices for treating liver disease  
Described are compositions and methods for treating liver disease, e.g., acute liver disease, using bone marrow-derived stem cells and bone marrow-derived stem cell conditioned media.
8171915 Fuel management system for variable ethanol octane enhancement of gasoline engines  
Fuel management system for efficient operation of a spark ignition gasoline engine. Injectors inject an anti-knock agent such as ethanol directly into a cylinder of the engine. A fuel management...
US20120110470 TOUCH-BASED SYSTEM FOR TRANSFERRING DATA  
Data transfer system. The system transfers data by touch from a first digital device to a second digital device and includes a first digital device having a touch screen along with a second digital...
US20120109610 METHODS AND APPARATI FOR PREDICTING AND QUANTIFYING THREAT BEING EXPERIENCED BY A MODELED SYSTEM  
A method predicts and quantifies the threat posed to a human-operated device based on an optimal device trajectory through a constraint-bounded corridor. A model of the device together with a model...
US20120108548 MOLECULAR TWEEZERS FOR THE TREATMENT OF AMYLOID-RELATED DISEASES  
This invention provides novel compositions to inhibit the aggregation of amyloid proteins. In various embodiments the compositions comprise a molecular tweezers that binds lysine and/or arginine...
US20120108041 Patterning of Nanostructures  
A technique for forming nanostructures including a definition of a charge pattern on a substrate and introduction of charged molecular scale sized building blocks (MSSBBs) to a region proximate the...
US20120107893 MICROBIAL ENGINEERING FOR THE PRODUCTION OF CHEMICAL AND PHARMACEUTICAL PRODUCTS FROM THE ISOPRENOID PATHWAY  
The invention relates to the production of one or more terpenoids through microbial engineering, and relates to the manufacture of products comprising terpenoids.
US20120107820 Multiplexed Quantitative PCR End Point Analysis of Nucleic Acid Targets  
Certain embodiments of the present invention are directed to one pot multiplexed quantitative PCR methods for end point analysis of a plurality of nucleic acid targets in a complex sample without...
US20120107371 STIMULI-RESPONSIVE SYSTEMS FOR CONTROLLED DRUG DELIVERY  
A method of delivering a therapeutic agent by providing a cross-linked polymer encapsulating the therapeutic agent to a site in a patient. The degradation rate of the cross-linked polymer is...
US20120107241 Particles for Inhalation Having Sustained Release Properties  
The invention generally relates to a method for pulmonary delivery of therapeutic, prophylactic and diagnostic agents to a patient wherein the agent is released in a sustained fashion, and to...
US20120106298 GESTURE RECOGNITION APPPARATUS AND METHOD  
The disclosure provides a gesture recognition apparatus and method. The gesture recognition apparatus includes an ultrasound transmitter, an ultrasound receiver, a dividing module, a computing...
US20120104990 Alkali Metal Ion Battery with Bimetallic Electrode  
Electrochemical cells having molten electrodes having an alkali metal provide receipt and delivery of power by transporting atoms of the alkali metal between electrode environments of disparate...
US20120103456 ARTICLES AND METHODS FOR REDUCING HYDRATE ADHESION  
This invention relates generally to articles, devices, and methods for gas hydrate mitigation in deep-sea drilling applications. In certain embodiments, hydrate-phobic surfaces are provided that...
8168879 Solar thermoelectric conversion  
Systems and methods utilizing solar-electrical generators are discussed. Solar-electrical generators are disclosed having a radiation-capture structure and one or more thermoelectric converters....
8168326 Battery structures, self-organizing structures and related methods  
An energy storage device includes a first electrode comprising a first material and a second electrode comprising a second material, at least a portion of the first and second materials forming an...
US20120099090 SYSTEM AND METHODS RELATED TO GENERATING ELECTROMEGNETIC RADIATION INTERFERENCE PATTERNS  
Systems and methods related to the generation of interference patterns using electromagnetic radiation are generally described. Some embodiments are directed to the use of such systems and methods...
8165423 Portable device having vibration reduction function and vibration reduction methode thereof  
A portable device includes a central processing unit, a vibration sensor to sense vibration of the portable device, an image processing unit to process image data, and a memory unit storing a...
8164384 Asymmetric multilevel outphasing architecture for RF amplifiers  
A radio frequency (RF) circuit includes a power supply configured to generate a plurality of voltages, a plurality of power amplifiers, each having an RF output port and a power supply input port,...
8163374 Formation of close-packed sphere arrays in V-shaped grooves  
The present invention relates to the self-assembly of a spherical-morphology block copolymer into V-shaped grooves of a substrate. Although spherical morphology block copolymers typically form a...
US20120095435 DELIVERY OF A SOLID BODY AND/OR A FLUID USING A LINEAR LORENTZ-FORCE ACTUATED NEEDLE-FREE JET INJECTION SYSTEM  
A method for transferring a solid body across a surface of a biological body includes (i) applying an electrical input to a controllable electromagnetic actuator; (ii) producing with the...
US20120094390 Fluorescent Sensor and Methods  
Binding an analyte can cause a change in fluorescence emission of a sensor. The change in fluorescence can be related to the amount of analyte present. The sensor can include a semiconductor...
US20120094060 Methods and Apparatus for Digital Composites  
In exemplary implementations of this invention, a digital material comprising many discrete units is used to fabricate a sparse structure. The units are reversibly joined by elastic connections....
8160404 High speed and low loss GeSi/Si electro-absorption light modulator and method of fabrication using selective growth  
An optoelectronic device includes an input waveguide structure that receives an input optical signal. A GeSi/Si waveguide structure receives from the input waveguide the input optical signal and...
8159680 Single-transducer, three-dimensional laser imaging system and method  
Disclosed herein are a system and method for three-dimensional imaging using a single transducer. A laser in a transmitter emits a sequence of short pulses, each of which is at a different center...
8158437 Luminescent detection of hydrazine and hydrazine derivatives  
The present invention generally relates to methods for modulating the optical properties of a luminescent polymer via interaction with a species (e.g., an analyte). In some cases, the present...
8158338 Resist sensitizer  
Methods and compositions for enhancing the sensitivity of a resist composition are disclosed. In one aspect, compositions for use with a matrix material (e.g., a lithographically sensitive...