Patents and Patent Applications from Massachusetts Institute of Technology MIT


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US20090287016 Transition-Metal-Catalyzed Carbon-Nitrogen and Carbon-Carbon Bond-Forming Reactions  
One aspect of the present invention relates to ligands for transition metals. A second aspect of the present invention relates to the use of catalysts comprising these ligands in various...
US20090282978 Microfluidic Separators for Multiphase Fluid-Flow Based On Membranes  
One aspect of the invention relates to fluid-phase separators and devices containing them. Another aspect of the invention relates to the use of said fluid-phase separators and devices containing...
7619224 Generation, acceleration, focusing and collection of a high-brightness, space-charge-dominated circular charged-particle beam  
A high-brightness, space-charge-dominated circular charged-particle beam system includes a flat circular emitter that emits charge particles to form a space-charge-dominated circular...
7618680 Oxidative chemical vapor deposition of electrically conductive and electrochromic polymers  
Remarkably, disclosed herein is a solvent-less chemical vapor deposition (CVD) method for the oxidative polymerization and deposition of thin films of electrically-conducting polymers. In a...
7618381 Wrist and upper extremity motion  
Wrist and upper extremity motion systems and method may include positioning a subject's wrist or upper extremity in a motion device, and actuating one or more motors associated with the device to...
7617891 Mechanical crawler  
A self-propelled mechanical crawler adapted to move on a medium. One example of such a crawler includes a foot, a wave generator adapted to drive a periodic wave in the foot, and a wave transfer...
US20090280518 SYSTEM FOR HIGH THROUGHPUT MEASUREMENT OF MECHANICAL PROPERTIES OF CELLS  
A system for measuring a mechanical property of a cell is provided. The system includes a body having a channel therethrough with a first end and a second end, the channel including at least one...
7616826 Removing camera shake from a single photograph using statistics of a natural image  
A computer method and system for deblurring an image is provided. The invention method and system of deblurring employs statistics on distribution of intensity gradients of a known model. The known...
7616084 Variable reluctance fast positioning system and methods  
The preferred embodiments of the present invention are directed to high bandwidth positioning systems such as fast tool servos (FTS). The applications of this invention include, for example,...
7615377 Fluorescein-based metal sensors  
The present invention is directed, in part, to fluorescein-based ligands for detection of metal ions, and methods of making and using the same.
US20090274654 METHODS AND DEVICES FOR THE SUSTAINED RELEASE OF MULTIPLE DRUGS  
The invention relates to an drug delivery device and a method for delivering multiple drugs over a prolonged period of time. The drug delivery device has two or more unitary segments comprising a...
US20090274418 REDUCTION OF SUBSTRATE OPTICAL LEAKAGE IN INTEGRATED PHOTONIC CIRCUITS THROUGH LOCALIZED SUBSTRATE REMOVAL  
Structures including optical waveguides disposed over substrates having a chamber or trench defined therein, and methods for formation thereof.
US20090273560 Sensor-based distributed tangible user interface  
A distributed tangible user interface comprises compact, self-powered, tangible user interface manipulative devices having sensing, display, and wireless communication capabilities, along with one...
US20090272657 DEVICES AND PROCESSES FOR ANALYZING NUCLEIC ACID DAMAGE AND REPAIR USING ELECTROPHORESIS  
Systems, methods, and devices are provided for assessing DNA damage and repair in cells by measuring DNA migration under electrophoresis. In one exemplary embodiment, a microarray configured to...
US20090272127 Cryogenic vacuum break thermal coupler with cross-axial actuation  
A system and method to connect a cryocooler (refrigerator) to a superconducting magnet or cooled object allows for replacement without the need to break the cryostat vacuum or the need to warm up...
7612346 Non-axisymmetric charged-particle beam system  
The charged-particle beam system includes a non-axisymmetric diode forms a non-axisymmetric beam having an elliptic cross-section. A focusing element utilizes a magnetic field for focusing and...
US20090269619 Multifunctional biomaterials as scaffolds for electronic, optical, magnetic, semiconducting, and biotechnological applications  
One-dimensional ring structures from M13 viruses were constructed by two genetic modifications encoding binding peptides and synthesis of a heterobifunctional linker molecule. The bifunctional...
US20090269491 Carbon-Polymer Electrochemical Systems and Methods of Fabricating Them Using Layer-by-Layer Technology  
One aspect of the invention provides ion-exchange and gas-diffusion membranes, fabricated by a layer-by-layer approach, for use, e.g., in electrochemical cells; a process for making membrane...
US20090269342 Hemagglutinin Polypeptides, and Reagents and Methods Relating Thereto  
The present invention provides a system for analyzing interactions between glycans and interaction partners that bind to them. The present invention also provides HA polypeptides that bind to...
US20090269326 Compositions of and methods of using sulfatases from flavobacterium heparinum  
This invention is related, in part, to sulfatase enzymes and methods of their use.
US20090268628 Synchronous Circuit Synthesis Using An Asynchronous Specification  
A method for specifying and synthesizing a synchronous digital circuit by first accepting a specification of an asynchronous system in which stored values are updated according to a set of state...
US20090265839 Fluid Safety Liner  
A fluid safety liner includes a liner of closed-cell foam that uses a series of channels and reservoirs to spread forces and distribute fluid contained within the liner throughout different areas...
US20090263805 Methods of identifying point mutations in a genome that affect the risk for or the age of appearance of disease  
The invention relates to a method for identifying inherited point mutations in a targeted region of the genome in a large population of individuals and determining which inherited point mutations...
US20090263359 Particulate Delivery Vehicles for Embryoid Bodies  
The present invention provides a vehicle for delivering various chemicals, compositions and proteins to stem cells and embryoid bodies. The vehicle may be biocompatible and biodegradable polymer...
US20090262794 DIGITAL TRANSMITTER  
An equalizer provided in a digital transmitter compensates for attenuation in a signal channel to a digital receiver. The equalizer generates signal levels as a logical function of bit history to...
US20090260667 Solar Thermoelectric Conversion  
Systems and methods utilizing solar-electrical generators are discussed. Solar-electrical generators are disclosed having a radiation-capture structure and one or more thermoelectric converters....
7606777 High-performance vision system exploiting key features of visual cortex  
An artificial visual recognition system and method employ a digital processor and a model executed by the digital processor. The model has a loose hierarchy of layers. Each layer, from a lowest...
7606499 Bidirectional transceiver assembly for POF application  
A bidirectional transceiver assembly includes a VCSEL structure that emits light at a defined wavelength on a substrate structure. A photodetector receives the light. A hole structure is formed on...
7604422 Large-aperture focal plane shutter  
Described is a compact focal plane shutter system adapted for large-format exposure shutters. The focal plane shutter includes at least one multi-segmented screen having multiple rigid blades. Each...
US20090258797 SYSTEMS FOR FILLING A SAMPLE ARRAY BY DROPLET DRAGGING  
Systems for filling sample array by droplet dragging are provided. One aspect of the invention provides an array filling system for filling a platen having a platen surface and an array of...
US20090258057 Synthetically Functionalized Living Cells  
Uniform, functional polymer patches can be attached to a fraction of the surface area of living individual cells. These surface-modified cells remain viable after attachment of the functional...
US20090258045 STRUCTURES INCLUDING ANTIMICROBIAL PEPTIDES  
A structure includes a substrate and a first plurality of bilayers on the substrate. The first plurality of bilayers includes a first layer including an antimicrobial peptide having a charge, and a...
7603704 Secure execution of a computer program using a code cache  
Hijacking of an application is prevented by monitoring control flow transfers during program execution in order to enforce a security policy. At least three basic techniques are used. The first...
7603239 Methods and systems for generating peptides  
Antimicrobial peptides are small proteins used by the innate immune system to combat bacterial infection in multicellular eukaryotes. There is mounting evidence that these peptides are less...
7602858 Digital transmitter  
An equalizer provided in a digital transmitter compensates for attenuation in a signal channel to a digital receiver. The equalizer generates signal levels as a logical function of bit history to...
7602857 Digital transmitter  
An equalizer provided in a digital transmitter compensates for attenuation in a signal channel to a digital receiver. The equalizer generates signal levels as a logical function of bit history to...
7601977 Phase-matched terahertz emitter  
Methods and apparatus are disclosed for directing optical radiation to make multiple passes across an extended region of an electro-optic material, where during each pass the electro-optic material...
7601424 Stabilized semiconductor nanocrystals  
A semiconductor nanocrystal associated with a polydentate ligand. The polydentate ligand stabilizes the nanocrystal.
US20090253224 Nanocrystal structures  
A structure including a grating and a semiconductor nanocrystal layer on the grating, can be a laser. The semiconductor nanocrystal layer can include a plurality of semiconductor nanocrystals...
7599876 Electronic market-maker  
Disclosed herein is an automated Electronic Market-Maker, comprising a Market Quality Control Module for generating trading recommendations to maintain market quality; an Inventory Control Module...
7599584 Planar MID-IR integrated microphotonics  
A planar mid-infrared (mid-IR) integrated microphotonic platform includes at least one laser performing lasing functions. The at least one laser comprises chalcogenide glass. At least amplifier...
7598199 Catalytic nanoparticles for nerve-agent destruction  
The present invention relates to compositions and methods for sorbing (e.g., adsorption and chemisorption) and destroying organophosphate chemical agents. In certain embodiments, the invention...
7597950 Nanoparticles having sub-nanometer features  
An article has a surface, at least a portion of which has a local radius of curvature of about 1000 nm or less. For example, the article may be a nanoparticle or a surface, a portion of which has a...
7597860 Low current plasmatron fuel converter having enlarged volume discharges  
A novel apparatus and method is disclosed for a plasmatron fuel converter (“plasmatron”) that efficiently uses electrical energy to produce hydrogen rich gas. The volume and shape of the plasma...
7597692 Microscission processes and procedures  
The present invention relates to microscission methods and devices used for the manipulation or modification of the body tissue by the formation of microconduits in a tissue. The term...
US20090248874 METHOD AND APPARATUS FOR DISTRIBUTING REQUESTS AMONG A PLURALITY OF RESOURCES  
The invention relates to a method and apparatus for distributing a request to one of a plurality of resources. A request is mapped to a location in mathematical mapping space. Each of the plurality...
US20090246167 STIMULI-RESPONSIVE SYSTEMS FOR CONTROLLED DRUG DELIVERY  
A method of delivering a therapeutic agent by providing a cross-linked polymer encapsulating the therapeutic agent to a site in a patient. The degradation rate of the cross-linked polymer is...
US20090246142 Triggered Self-Assembly of Nanoparticles In Vivo  
The present invention provides triggered self-assembly nanosystems. Such nanosystems comprise a population of triggered self-assembly conjugates, each conjugate comprising one or more monomeric...
US20090245322 OPTICAL CHARACTERIZATION OF PHOTONIC INTEGRATED CIRCUITS  
In one aspect, the present invention provides techniques and apparatus for optical characterization of photonic devices and/or circuits. By way of example, the techniques can be used to identify...
US20090244300 METHOD AND APPARATUS FOR MOTION INVARIANT IMAGING  
Object motion during camera exposure often leads to noticeable blurring artifacts. Proper elimination of this blur is challenging because the blur kernel is unknown, varies over the image as a...