Patents and Patent Applications from Massachusetts Institute of Technology MIT


Match Document Document Title
7993905 Device containing cytophilic islands that adhere cells separated by cytophobic regions  
The invention provides a device for adhering cells in a specific and predetermined position, and associated methods. The device includes a plate defining a surface and a plurality of cytophilic...
7993608 Fluid injection port  
Fluid injection port. An elastomeric injection nipple is supported within a compression fitting and the injection nipple includes a slit. A first via is provided that connects the slit in the...
US20110191868 METHODS FOR IDENTIFICATION AND USE OF AGENTS TARGETING CANCER STEM CELLS  
The invention relates to methods for identifying compounds and compositions that target cancer stem cells. In some aspects, the invention relates to treatment methods that use compounds and...
US20110191073 Methods and Apparatus for Direct-Global Separation of Light Using Angular Filtering  
In an exemplary implementation of this invention, light from a scattering scene passes through a spatial light attenuation pattern and strikes a sensor plane of a camera. Based on said camera's...
US20110190457 PROTECTIVE POLYMERIC MATERIALS AND RELATED DEVICES  
The present invention relates to polymeric materials having enhanced properties. In some cases, the materials may comprise polymers having shape-persistent portions which may enhance the mechanical...
US20110189749 TRAPPING, RECYCLING, AND OTHER TECHNIQUES INVOLVING CATALYSTS  
Trapping, recycling, and other techniques involving catalysts are provided by this invention. The present invention provides for the retention of catalysts and other immobilized entities within a...
US20110189717 MICROBIAL ENGINEERING FOR THE PRODUCTION OF CHEMICAL AND PHARMACEUTICAL PRODUCTS FROM THE ISOPRENOID PATHWAY  
The invention relates to recombinant expression of a taxadiene synthase enzyme and a geranylgeranyl diphosphate synthase (GGPPS) enzyme in cells and the production of terpenoids.
US20110189677 Methods For Preparing Sequencing Libraries  
Improvements in chromatin immunoprecipitation-high throughput sequencing techniques has allowed the creation of chromatin maps from limited biological sample sizes that cannot be evaluated using...
US20110187437 Radio-Frequency (RF) Amplifier Circuits and Related Techniques  
A power combining and outphasing system and related techniques for simultaneously providing both wide-bandwidth linear amplification and high average efficiency is described. Providing linear...
US20110187015 System and method for uniaxial compression of an article, such as a three dimensionally printed dosage form  
A uniaxially compressed dosage form manufactured by three-dimensional printing that preserves the predetermined internal architecture of the dosage form while producing an improved surface finish....
US20110187014 Method and Apparatus for Embossing a Deformable Body  
A deformable body is embossed using a stamp as a function of a pressure distribution. The pressure distribution is obtained by running a deformation model determined based on convolving a contact...
7989151 Resolution enhancement in optical lithography via absorbance-modulation enabled multiple exposures  
A method to enhance resolution in optical lithography via absorbance-modulation involves exposing an opaque absorbance modulation layer (AML) to a first waveform having wavelength, 81, with the...
7988746 Battery structures, self-organizing structures and related methods  
An energy storage device includes a first electrode comprising a first material and a second electrode comprising a second material, at least a portion of the first and second materials forming an...
US20110183867 Polymer arrays for biofilm adhesion testing  
This invention relates to a method of screening arrays of polymers having pre-determined surface energies. The polymer arrays of the present invention can be used to screen for microorganism...
US20110181644 Method and Apparatus for Controlling Film Deposition  
The disclosure relates to a method for depositing films on a substrate which may form part of an LED or other types of display. In one embodiment, the disclosure relates to an apparatus for...
US20110181128 GRID-TIED POWER CONVERSION CIRCUITS AND RELATED TECHNIQUES  
Circuit topologies and control methods for a power converter and are described.
7985594 Biradical polarizing agents for dynamic nuclear polarization  
The present invention provides methods for performing dynamic nuclear polarization using biradicals with a structure of formula (I) as described herein. In general, the methods involve (a)...
7984642 System and method for ultrasonic measuring of particle properties  
Devices, systems and methods for measuring and detecting properties of a variety of particles or cells in suspension. Properties, such as, for example, velocity of particles, concentration and/or...
US20110177564 BIOPROCESS AND MICROBE ENGINEERING FOR TOTAL CARBON UTILIZATION IN BIOFUEL PRODUCTION  
Some aspects of this invention provide methods and bioreactors for converting a carbon source into a lipid. In some embodiments, lipid production is carried out in an aerobic fermentor and carbon...
US20110177188 CEMENT-BASED MATERIALS SYSTEM FOR PRODUCING FERROUS CASTINGS USING A THREE-DIMENSIONAL PRINTER  
Mixture for use in a three-dimensional printer to make molds suitable for producing ferrous coatings. The mixture includes cement, sand and accelerator. Grain sizes of the cement, sand and...
US20110175035 EMISSIVE POLYMERS AND DEVICES INCORPORATING THESE POLYMERS  
The present invention relates to a class of luminescent and conductive polymer compositions having chromophores, and particularly solid films of these compositions exhibiting increased luminescent...
US20110174720 Multifunctional Electroprocessed Membranes  
Described is the application of layer-by-layer (LbL) electrostatic assembly techniques to electrospun nanofibers in order to fabricate novel, breathable electrospun fiber-based chemical and...
US20110173970 FLEXIBLE ACTUATOR BASED ON SHAPE MEMORY ALLOY SHEET  
A flexible unit-cell actuator includes a shape memory alloy sheet having a fold between adjacent legs in one state and a heat source that upon activation concentrates heating of the shape memory...
7983890 Method and apparatus performing automatic mapping for a multi-processor system  
A method, apparatus and computer program product for mapping and executing an application on a multi-processor system is presented. At least one array to be considered for distribution among...
7982777 Stereoscopic wide field of view imaging system  
A stereoscopic imaging system incorporates a plurality of imaging devices or cameras to generate a high resolution, wide field of view image database from which images can be combined in real time...
US20110172158 TARGETS, METHODS, AND REAGENTS FOR DIAGNOSIS AND TREATMENT OF SCHIZOPHRENIA  
The present invention provides targets, methods, and reagents for the diagnosis and treatment of schizophrenia and related conditions. The invention provides methods for the diagnosis of...
US20110171629 NANOSTRUCTURED DEVICES INCLUDING ANALYTE DETECTORS, AND RELATED METHODS  
The present invention provides compositions and devices comprising nanostructure networks, and related methods. The compositions may exhibit enhanced interaction between nanostructures, providing...
US20110170825 Waveguide Coupler Having Continuous Three-Dimensional Tapering  
A solid state waveguide coupler is provided including a first coupler end disposed on a solid state material substrate for connection to a first solid state waveguide located on the substrate and a...
US20110170624 SPACE-TIME DIGITAL POWER AMPLIFIER  
Described is a space-time digital power amplifier that can be used to generate an arbitrary waveform for a carrier signal. The space-time digital power amplifier employs temporal modulation of...
US20110169687 SYSTEM AND METHOD FOR DETECTING DAMAGE, DEFECT, AND REINFORCEMENT IN FIBER REINFORCED POLYMER BONDED CONCRETE SYSTEMS USING FAR-FIELD RADAR  
A non-contact, far-field radar nondestructive testing (NDT) method is disclosed that is capable of detecting at least one of defects, damages, and reinforcement conditions in near-surface region of...
US20110169117 Cross-Talk Suppression in Geiger-Mode Avalanche Photodiodes  
An avalanche photodiode detector is provided with a substrate including an array of avalanche photodiodes. An optical interface surface of the substrate is arranged for accepting external input...
US20110168630 GRAFT COPOLYMERS, METHODS FOR GRAFTING HYDROPHILIC CHAINS ONTO HYDROPHOBIC POLYMERS, AND ARTICLES THEREOF  
The present invention relates to synthetic methods for grafting hydrophilic chains onto polymers, particularly hydrophobic polymers such as poly(vinyl chloride) (PVC), poly(vinylidene fluoride)...
7978805 Liquid gallium cooled high power neutron source target  
A neutron source includes a low atomic number element target that is bombarded by incident energetic particles to provide a neutron flux. The source receives a controlled flow of liquid gallium...
7977092 Methods for identifying candidate anti-tumorigenic agents  
Methods for identifying stem cells and other cells specific to embryogenesis and carcinogenesis, classifying tissue samples, diagnosing precancerous and cancerous or atherosclerotic lesions,...
7976815 Shape controlled growth of nanostructured films and objects  
A method and apparatus for growing nanostructures is presented. A growth substrate including at least one reaction site is provided as is a device disposed proximate the growth substrate. Energy is...
7976696 Mesostructured zeolitic materials and methods of making and using the same  
One aspect of the present invention relates to mesostructured zeolites. The invention also relates to a method of preparing mesostructured zeolites, as well as using them as cracking catalysts for...
US20110166549 BI-DIRECTIONAL MOTION OF A LORENTZ-FORCE ACTUATED NEEDLE-FREE INJECTOR (NFI)  
The present invention relate to a method and corresponding apparatus for just in time mixing of a solid or powdered formulation and its subsequent delivery to a biological body. In some...
US20110165681 Light-Activated Proton Pumps and Applications Thereof  
In a method for adjusting the voltage potential or pH of, or cause proton release from, cells, subcellular regions, or extracellular regions, a gene encoding for a light-driven proton pump is...
US20110165530 SWIRL-COUNTER-SWIRL MICROJETS FOR THERMOACOUSTIC INSTABILITY SUPPRESSION  
Combustor. The combustor includes an axially symmetric tube along with means for introducing fuel and air into the tube. A swirler is disposed within the tube to impart rotation in a first...
US20110163469 HIGH-THROUGHPUT FABRICATION OF MICROPARTICLES  
The high-throughput fabrication of microparticles based on the double emulsion/solvent evaporation technique for screening and optimizing microparticle formulations for particular characteristics...
US20110162957 SYSTEMS AND METHODS FOR ENHANCING GROWTH OF CARBON-BASED NANOSTRUCTURES  
Systems and methods generally directed to enhancing the growth of carbon-based nanostructures are described. In some embodiments, electromagnetic radiation can be used to enhance carbon-based...
7971572 Fuel management system for variable ethanol octane enhancement of gasoline engines  
Fuel management system for efficient operation of a spark ignition gasoline engine. Injectors inject an anti-knock agent such as ethanol directly into a cylinder of the engine. A fuel management...
US20110161259 SYSTEM AND METHOD FOR SIMPLIFICATION OF A MATRIX BASED BOOSTING ALGORITHM  
A method for simplification of a matrix based boosting algorithm divides a feature set comprising a plurality of feature data into several subsets, and assigns a number to each subset. The method...
US20110158584 LOW-LOSS BLOCH WAVE GUIDING IN OPEN STRUCTURES AND HIGHLY COMPACT EFFICIENT WAVEGUIDE-CROSSING ARRAYS  
Low-loss waveguide structures may comprise a multimode waveguide supporting a periodic light intensity pattern, and attachments disposed at the waveguide adjacent low-intensity regions of the light...
US20110158553 PORTABLE DEVICE HAVING VIBRATION REDUCTION FUNCTION AND VIBRATION REDUCTION METHODE THEREOF  
A portable device includes a central processing unit, a vibration sensor to sense vibration of the portable device, an image processing unit to process image data, and a memory unit storing a...
US20110158539 SYSTEM AND METHOD FOR EXTRACTING FEATURE DATA OF DYNAMIC OBJECTS  
A system and method for extracting feature data of dynamic objects selects sequential N frames of a video file up front, where N is a positive integer, and divides each of the N frames into N*N...
7971252 Generating a multiple-prerequisite attack graph  
In one aspect, a method to generate an attack graph includes determining if a potential node provides a first precondition equivalent to one of preconditions provided by a group of preexisting...
7970022 Surface-emitting fiber laser  
In one aspect, the disclosure features an article, including a fiber waveguide extending along a waveguide axis, the fiber waveguide including a core extending along the waveguide axis and a...
7967016 Apparatus and method for laser treatment with spectroscopic feedback  
A platform Smart Scalpel system using rapid real-time feedback for effecting laser treatment. The platform system includes an imaging system for rapid real-time detection of tissue characteristics,...
US20110153302 IDENTIFICATION OF DRUG EFFECTS ON SIGNALING PATHWAYS USING INTEGER LINEAR PROGRAMMING  
Methods and algorithms for modeling biological interaction networks using integer linear programming (ILP) are provided. Methods to identify the effect of a drug on such interaction networks are...