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Patents and Patent Applications from Massachusetts Institute of Technology MIT


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US20130302348 AGENTS FOR INFLUENZA NEUTRALIZATION  
The present invention provides antibodies (e.g., monoclonal antibodies, human antibodies, humanized antibodies, etc.), which bind to multiple influenza strains. Such antibodies are useful, for...
US20130301117 METHODS, SYSTEMS, AND APPARATUS FOR HIGH ENERGY OPTICAL-PULSE AMPLIFICATION AT HIGH AVERAGE POWER  
An inventive composite optical gain medium capable includes a thin-disk gain layer bonded to an index-matched cap. The gain medium's surface is shaped like a paraboloid frustum or other truncated...
US20130300357 APPARATUS FOR WIRELESSLY CHARGING ENERGY STORAGE ELEMENTS  
An apparatus for wirelessly charging an energy storage element is disclosed. The apparatus includes a coil, a set of capacitors, a set of switches and a rectifier. The coil, which has multiple...
US20130299389 MESOSTRUCTURED ZEOLITIC MATERIALS, AND METHODS OF MAKING AND USING THE SAME  
One aspect of the present invention relates to mesostructured zeolites. The invention also relates to a method of preparing mesostructured zeolites, as well as using them as cracking catalysts for...
8583291 Methods and apparatus for energy demand management  
To manage energy demands of a plurality of appliances, a meter controller apparatus receives a first message from a first appliance controller apparatus coupled to a first appliance of the...
8581698 Method, apparatus and computer program product for facilitating location discovery  
A method, apparatus and computer program product are provided to permit location discovery, including location discovery in indoor settings. The method may identify a wireless signature present at...
8581525 Compensated precessional beam extraction for cyclotrons  
A plurality of magnetic extraction bumps are incorporated into a cyclotron that further includes (a) a pair of magnetic coils encircling a central axis and positioned on opposite sides of a median...
8580430 Battery structures, self-organizing structures, and related methods  
An energy storage device includes a first electrode comprising a first material and a second electrode comprising a second material, at least a portion of the first and second materials forming an...
8580253 Immunomodulating compositions and methods of use  
This invention is directed to β-1-6-glucans, compositions and devices comprising the same, and methods of use thereof in modulating immune responses. The β-1-6-glucans of certain embodiments of t...
8580100 Metal deposition using seed layers  
Methods of forming a conductive metal layers on substrates are disclosed which employ a seed layer to enhance bonding, especially to smooth, low-roughness or hydrophobic substrates. In one aspect...
US20130297781 Methods and Apparatus for Tuning a Network for Optimal Performance  
In exemplary implementations of this invention, one or more computer processors receive electronic data indicative of, or compute (i) at least three different topologies of a network and (ii) a...
US20130297070 Robot having obstacle avoidance mechanism  
A system includes a driver robot having a body with a pair of spaced apart flux conductors, and a follower robot having an articulated body with a pair of spaced apart magnets. The magnets are...
US20130296746 Elastic Element Exoskeleton and Method of Using Same  
Running in a mammal, such as a human, is augmented by adaptively modulating anticipation of maximum leg extension of a mammal when running, and actuating an exoskeletal clutch linked in series to...
US20130296707 USER INTERFACE FOR ULTRASOUND SCANNING SYSTEM  
An ultrasound scanning system includes a graphical user interface that provides visually intuitive feedback to a user to assist the user in properly aligning an ultrasound scanner to a desired...
US20130295588 COUNTING PARTICLES USING AN ELECTRICAL DIFFERENTIAL COUNTER  
This disclosure relates to methods and devices to count particles of interest, such as cells. The methods include obtaining a fluid sample that may contain particles of interest; counting all types...
US20130295338 Methods and Apparatus for Computer-Assisted Spray Foam Fabrication  
In exemplary implementations of this invention, a nozzle sprays foam, layer by layer, to fabricate a fabricated object according to a CAD model, and a subtractive fabrication tool removes material...
US20130295143 ELECTROPROCESSING OF ACTIVE PHARMACEUTICAL INGREDIENTS  
Electrospinning of crystalline particles comprising active pharmaceutical ingredients (API) from suspensions yields fibrous compositions comprising the API. The morphology and size of the...
US20130295129 IMMUNOSTIMULATORY COMPOSITIONS AND METHODS OF USE THEREOF  
Lipid conjugates for enhanced delivery of cargo to the lymph nodes are disclosed. The lipid conjugates typically include three domains: a lipophilic domain that binds to albumin, a polar block...
US20130292300 MESOSTRUCTURED ZEOLITIC MATERIALS SUITABLE FOR USE IN HYDROCRACKING CATALYST COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME  
Hydrocracking processes and catalyst composition for use therein are provided. The catalyst compositions described herein include a mesoporous support material and at least one catalytic metal...
US20130292039 Methods and Apparatus for Actuated Fabricator  
In exemplary implementations of this invention, an actuated fabricator deposits structural elements (e.g., tensile structural elements) in a 3D pattern over large displacements. The fabricator is...
8577997 Global hosting system  
Network architecture supports hosting and content distribution on a global scale. The architecture allows a Content Provider to replicate and serve its most popular content at an unlimited number...
8577535 System and method for providing perceived first-order control of an unmanned vehicle  
A system for providing perceived first order control of an unmanned vehicle contains a memory and a processor configured by the memory to perform the steps of: receiving instructions for updating...
8574914 Methods for mobile zinc measurement  
This invention relates to a method for using a zinc sensor compound to detect a disease associated with the disruption of zinc homeostasis, such as prostate cancer. The zinc sensor compound...
8574832 Methods for preparing sequencing libraries  
Improvements in chromatin immunoprecipitation-high throughput sequencing techniques has allowed the creation of chromatin maps from limited biological sample sizes that cannot be evaluated using...
8574713 Superhydrophobic fibers and methods of preparation and use thereof  
The present invention relates to fibers exhibiting a water contact angle of above 150° and water contact angle hysteresis of below 15°, methods of producing the same, and applications thereof. T...
8574704 Liquid-impregnated surfaces, methods of making, and devices incorporating the same  
The invention is directed to an article with a liquid-impregnated surface, the surface having a matrix of features thereupon, spaced sufficiently close to stably contain a liquid therebetween or...
US20130290970 UNIPROCESSOR SCHEDULABILITY TESTING FOR NON-PREEMPTIVE TASK SETS  
A method of determining schedulability of tasks for uniprocessor execution includes defining a well-formed, non-preemptive task set having a plurality of tasks, each task having at least one...
US20130289931 METHODS, APPARATUSES AND COMPUTER PROGRAM PRODUCTS FOR DETERMINING SPEED OF MOVEMENT OF A DEVICE AND DEVICE POSE CLASSIFICATION  
An apparatus for determining a speed of cyclic motion of a device or user and one or more poses of a device may include a processor and memory storing executable computer code causing the apparatus...
US20130289687 Nanowired Three Dimensional Tissue Scaffolds  
Electrically conductive nanowires incorporated within scaffolds enhance tissue growth, bridge the electrically resistant pore walls and markedly improve electrical communication between adjacent...
US20130289520 TARGETED AND LIGHT-ACTIVATED CYTOSOLIC DRUG DELIVERY  
The present invention provides methods and compositions for highly precise spatial and temporal control over cytosolic delivery of compounds, in particular, those compounds that would otherwise be...
US20130288463 METHOD FOR PRODUCING THIN LAYERS OF CRYSTALLINE OR POLYCRYSTALLINE MATERIALS  
Method for making thin crystalline or polycrystalline layers. The method includes electrochemically etching a crystalline silicon template to form a porous double layer thereon, the double layer...
US20130287743 METHOD FOR DIFFERENTIATING HUMAN EMBRYONIC STEM CELLS INTO ß-CELLS FOR THE TREATMENT OF TYPE I DIABETES  
The invention provides inter alia methods for differentiating embryonic stem cells into insulin producing cells, as well as compositions comprising such cells, and therapeutic uses of such...
US20130285399 CLAMP ASSEMBLY INCLUDING PERMANENT MAGNETS AND COILS FOR SELECTIVELY MAGNETIZING AND DEMAGNETIZING THE MAGNETS  
A clamp assembly comprises a first clamp including a plurality of magnet devices. Each magnet device includes a permanent magnet and a coil surrounding the permanent magnet. The clamp assembly...
8571214 Secure network coding for multi-resolution wireless video streaming  
Described herein is a method and system for hierarchical wireless video with network coding which limits encryption operations to a critical set of network coding coefficients in combination with...
8571080 High efficiency slab-coupled optical waveguide laser and amplifier  
A slab-coupled optical waveguide laser (SCOWL) is provided that includes an upper and lower waveguide region for guiding a laser mode. The upper waveguide region is positioned in the interior...
8569226 High affinity metal-oxide binding peptides with reversible binding  
A dodecamer peptide, and its modified variant, having a repeating glycine-lysine sequence was created and found to bind with high affinity to oxide surfaces and certain activated polymeric...
8569099 Enhanced methods for fabricating solar cells with textured surfaces  
Semiconductor photovoltaic cells have surfaces that are textured for processing and photovoltaic reasons. The absorbing regions may have grooves that reduce loss of solar energy that would...
8569046 Microarray with microchannels  
A microarray formed in a planar surface of a moldable slab, the microarray including a plurality of microwell sets comprising a plurality of microwells formed in the planar surface of the moldable...
8568685 Separation of nanostructures  
The present invention generally relates to the separation of one or more populations of nanostructures from one or more other populations of nanostructures based upon differences in density. An...
8568611 Oxide coatings on lithium oxide particles  
The present invention generally relates to unique coatings for use with energy storage particles, such as lithium oxide energy storage materials. The invention provides unique coatings for...
US20130282141 Variable Impedance Mechanical Interface  
A mechanical interface connecting a biological body segment, such as a limb, portion of a limb or other body segment, to a wearable device such as a prosthetic, orthotic or exoskeletal device, is...
US20130281706 OLEFIN METATHESIS CATALYSTS AND RELATED METHODS  
The present invention provides methods for the synthesis of catalysts and precursors thereof. Methods of the invention may comprise combining a catalyst precursor and at least one ligand to...
US20130280920 Templated Monolayer Polymerization and Replication  
A self-replicating monolayer system employing polymerization of monomers or nanoparticle ensembles on a defined template provides synthesis of two-dimensional single molecule polymers. Systems of...
US20130280782 PROTEIN-BASED CONJUGATES AND SELF-ASSEMBLED NANOSTRUCTURES  
The present disclosure provides protein-containing compositions, methods and uses thereof. A conjugate comprises a globular protein conjugated with a polymer that preserves the folded and...
US20130280485 Superhydrophobic and Oleophobic Functional Coatings Comprised of Grafted Crystalline Polymers Comprising Perfluoroalkyl Moieties  
Described herein are methods of preparing superhydrophobic and oleophobic surfaces by grafting poly(perfluoroalkyl acrylate) chains on silicon substrates with initiated chemical vapor deposition....
US20130280334 Nanostructured Gels Capable of Controlled Release of Encapsulated Agents  
Self-assembled gel compositions including a gelator, e.g., an enzyme-cleavable gelator, e.g., having a molecular weight of 2500 or less, are described. The self-assembled gel compositions can...
US20130280249 Directed Engagement Of Activating Fc Receptors  
The present invention features engineered proteins that include a first polypeptide that specifically binds a first target (e.g., a cellular target, such as a cell-surface antigen) and a second...
US20130279850 THREE-DIMENSIONAL PERIODIC DIELECTRIC STRUCTURES HAVING PHOTONIC DIRAC POINTS  
The dielectric, three-dimensional photonic materials disclosed herein feature Dirac-like dispersion in quasi-two-dimensional systems. Embodiments include a face-centered cubic (fcc) structure...
US20130278756 Sensor for Simultaneous Measurement of Thickness and Lateral Position of a Transparent Object  
System for measuring thickness and lateral position of a transparent object. The system includes a camera having a sensor for receiving light, the camera including an objective lens for focusing on...
US20130278455 EFFICIENT PULSE DOPPLER RADAR WITH NO BLIND RANGES, RANGE AMBIGUITIES, BLIND SPEEDS, OR DOPPLER AMBIGUITIES  
A Doppler radar system that avoids blind ranges, range ambiguities, blind speed and/or Doppler ambiguities. Pulse width, repetition interval and pulse type are varied from pulse to pulse within a...