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Patents and Patent Applications from Massachusetts Institute of Technology MIT


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8666547 Cellular automotion digital material  
Cellular automotion digital material is useable for rapid prototyping and fabrication of continuous string conformations and two- or three-dimensional shapes through actuation of a string, surface,...
8664640 Non-volatile memory device including semiconductor charge-trapping material particles  
A memory device can include an active layer that has a selectable lateral conductivity. The layer can include a plurality of nanoparticles.
8663522 Fiber draw synthesis  
Fiber draw synthesis process. The process includes arranging reactants in the solid state in proximate domains within a fiber preform. The preform is fluidized at a temperature below the melting...
8662552 Dexterous and compliant robotic finger  
A robotic finger that includes multiple phalanges, each phalange configured to be compliantly actuated. The robotic finger also includes compliant touch sensors that, in combination with the...
US20140059248 Global hosting system  
Network architecture supports hosting and content distribution on a global scale. The architecture allows a Content Provider to replicate and serve its most popular content at an unlimited number...
US20140058667 LOCALIZATION AND TRACKING SYSTEM FOR MOBILE ROBOTS  
Localization and tracking system. The system includes at least one laser mounted for pointing its beam at arbitrary locations within a three-dimensional space. An object within the...
US20140058069 PARTICLES AND OTHER SUBSTRATES USEFUL IN PROTEIN PURIFICATION AND OTHER APPLICATIONS  
The present invention generally relates to particles, including microgel particles, for purifying proteins and other species. In one aspect, the particles comprise a metal-chelating moiety, which...
US20140057966 METASTASIS SPECIFIC SPLICE VARIANTS OF MENA AND USES THEREOF IN DIAGNOSIS, PROGNOSIS AND TREATMENT OF TUMORS  
Methods and kits for diagnosis, prognosis and treatment of metastatic tumors are provided where the metastatic tumor is characterized by changes in expression of +++, ++ and/or 11a variants of Mena.
US20140056913 ANTI-DENGUE VIRUS ANTIBODIES AND USES THEREOF  
The present invention provides, among other things, antibody agents (e.g., antibodies, and/or antigen-binding fragments thereof) that bind to DV epitopes, as well as compositions containing them...
US20140056334 ENHANCED COMMUNICATION OVER NETWORKS USING JOINT MATRIX DECOMPOSITIONS  
The disclosure describes examples of systems and methods for communication networks including multiple-input multiple output MIMO channels. In these examples, based on a novel decomposition of two...
US20140054809 METHOD AND APPARATUS FOR A POROUS ELECTROSPRAY EMITTER  
An ionic liquid ion source can include a microfabricated body including a base and a tip. The body can be formed of a porous material compatible with at least one of an ionic liquid or...
US20140054732 METHOD AND APPARATUS FOR RELEASE-ASSISTED MICROCONTACT PRINTING OF MEMS  
The disclosure provides methods and apparatus for release-assisted microcontact printing of MEMS. Specifically, the principles disclosed herein enable patterning diaphragms and conductive membranes...
8660374 Selecting transform paths for compressing visual data  
Encoding data includes: determining multiple patterns for computing one-dimensional transforms over a first array of data elements. Each pattern includes multiple subsets of data elements of the...
8659353 Asymmetric multilevel outphasing architecture for RF amplifiers  
A radio frequency (RF) circuit includes a power supply configured to generate a plurality of voltages, a plurality of power amplifiers, each having an RF output port and a power supply input port,...
8658699 Chemical permeation enhancers enhance nerve blockade by toxins  
Chemical permeation enhancers (CPEs) improve access of local anesthetics to the nerve, thereby improving their performance. Surfactants, representing three CPE sub-groups: anionic, cationic, and...
US20140052421 SYSTEM AND METHOD FOR WATER DISTRIBUTION MODELLING  
A method of modelling a water distribution system, the method comprising steps of: identifying a plurality of demand zones within said water distribution network; estimating water consumption data...
US20140052265 ROLLING-CONTACT KNEE PROSTHESIS  
A custom knee prosthetic includes a polycentric rolling contact joint, whose instantaneous center of rotation coincides with the instantaneous center of rotation of a patient's knee joint.
US20140051107 Method and Apparatus for Measuring Particle Characteristics through Mass Detection  
Method for measuring a target particle property. A suspended microchannel resonator is calibrated to determine the relationship between a detected mass and a resonance frequency shift of the...
US20140050707 MIR-150 FOR THE TREATMENT OF BLOOD DISORDERS  
The invention provides methods of treating certain blood related disorders, in particular, thrombocytopenia and anemia comprising increasing miR-150 expression or inhibiting miR-150 in progenitor...
US20140049318 Method and Apparatus for High Efficiency, High Dynamic Range Digital RF Power Amplification  
A digital, radio frequency (RF) power amplifier includes first and second RF digital to analog converters (RF DACs) and a combiner to combine output signals of the first and second RF DACs. In at...
US20140048126 VIRUS FILM AS TEMPLATE FOR POROUS INORGANIC SCAFFOLDS  
Virus multilayers can be used as templates for growth of inorganic nanomaterials. For example, layer-by-layer construction of virus multilayers on functionalized surfaces form nanoporous structures...
8656244 Rate adaptive nonbinary LDPC codes with low encoding complexity  
Described herein is a method and system that provides a class of error correction codes which can be used in communication systems to correct errors which may be introduced by a communication...
8656141 Architecture and programming in a parallel processing environment with switch-interconnected processors  
An integrated circuit includes a plurality of tiles. Each tile includes a pipelined processor configured to process multiple streams of instructions for the processor; and a switch including...
8655441 Methods and apparatus for monitoring patients and delivering therapeutic stimuli  
In an exemplary implementation of this invention, a user wears comfortable biosensors. These sensors gather physiological data from the user and transmit this data to another radio-enabled device....
8655114 Hitless tuning and switching of optical resonator amplitude and phase responses  
A hitless tunable filter may include a ring resonator, a Mach-Zehnder coupler, and first and second phase shifters. The Mach-Zehnder coupler may include a switching arm that is coupled to the ring...
8654234 Bi-directional screen  
A bidirectional screen alternately switches between a display mode showing conventional graphics and a capture mode in which the LCD backlight is disabled and the LCD displays a pinhole array or a...
8653867 Pulse modulated neural integrator circuit and associated phase locked loop  
A pulse modulated neural integrator circuit is comprised of discrete analog electronic components and has a plurality of discrete stable states. In some embodiments, the pulse modulated neural...
8653818 Parallel transmission RF pulse design with local SAR constraints  
A method of designing a parallel transmission radio frequency (RF) pulse for a magnetic resonance imaging (MRI) system includes compressing a model for a subject to be scanned by the MRI system...
8652797 Methods of NAD-dependent deacetylation of a lysine residue in a protein  
Methods of NAD-dependent of at least one lysine residue in an acetylated protein are disclosed. The methods include combining the acetylated protein with an isolated Sir2 protein or fragment that...
8652332 Liquid filtration using pressure difference across a hydrophobic membrane  
Method and devices for filtering liquid are provided that rely on pressure difference to filter liquid. In one embodiment, a device for filtering liquid includes a feed chamber, a permeate chamber,...
8651678 Polarization fields for dynamic light field display  
In exemplary implementations of this invention, a flat screen device displays a 3D scene. The 3D display may be viewed by a person who is not wearing any special glasses. The flat screen device...
8651183 Robotic exploration of unknown surfaces  
The subject matter describes a tactile sensing device comprising an end effector and a control unit. The control unit is capable of receiving tactile information from the at least one end effector....
US20140046455 POWERED ARTIFICIAL KNEE WITH AGONIST-ANTAGONIST ACTUATION  
A knee prosthesis comprises an agonist-antagonist arrangement of two series-elastic actuators in parallel, including a knee joint, flexion and extension actuators connected to the joint in parallel...
US20140044770 Compositions and Methods for Modulating BRD4 Bioactivity  
Compositions and methods for increasing or decreasing DNA repair are provided. Composition includes a Brd4 polypeptide, fragment, fusion, or variant thereof. The fusion protein can include a...
US20140044340 3D Radiometry  
Methods and a computer program product for deriving temperature information with respect to surfaces within a scene that is imaged radiometrically. A time sequence of radiometric data is acquired...
US20140042890 High Efficiency Incandescent Lighting  
Incandescent lighting structure. The structure includes a thermal emitter that can, but does not have to, include a first photonic crystal on its surface to tailor thermal emission coupled to, in a...
8649086 Apparatus and method for generating high-intensity optical pulses with an enhancement cavity  
An enhancement cavity includes a plurality of focusing mirrors, at least one of which defines a central aperture having a diameter greater than 1 mm. The mirrors are configured to form an optical...
8648802 Collapsible input device  
In exemplary implementations of this invention, a handheld, collapsible input device (CID) may be employed by a user to input and manipulate 3D information. The CID telescopes in length. As a user...
8648176 Engineered proteins with high affinity for DOTA chelates  
The present invention features, inter alia, compositions and methods for the treatment of cancer and infectious disease. The compositions include engineered proteins that specifically bind a metal...
8647477 High-efficiency thermal-energy-driven water purification system  
Water can be separated from a liquid composition (e.g., salt water) by directing a carrier gas flow through an evaporator and directly contacting the carrier gas flow with the liquid composition in...
US20140039849 METHOD FOR THE CONSTRUCTION OF A WATER DISTRIBUTION MODEL  
A method for the determination of demand zones for use with a water distribution model of a water distribution network, the method comprising the steps of: constructing polygons about clusters of...
US20140037873 Digital Flexural Materials  
Digital flexural materials are kits of discrete parts that can be assembled into a lattice structure to produce functionally useful assemblies. Digital flexural materials enable design of materials...
US20140037755 Mapkap Kinase-2 as a Specific Target for Blocking Proliferation of P53-Defective Cells  
The present invention relates to compounds and pharmaceutical compositions for treating cellular proliferative disorders, e.g., in patients having one or more p53-deficient cells, screening assays...
US20140037736 Targeting of Antigen Presenting Cells With Immunonanotherapeutics  
The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides nanocarriers capable of stimulating an immune response in...
US20140037593 Tricalcium Phosphate Binding Peptides And Uses Thereof  
The invention is directed to a composition comprising all or a portion of a beta-tricalcium phosphate (β-TCP) bound to all or a portion of a β-TCP binding peptide and methods of use thereof.
US20140035438 Passive, Self-Tuning Energy Harvester for Extracting Energy From Rotational Motion  
Energy harvester. The harvester includes a radially extending beam having a proximal end mounted a selected distance from an axis of rotation of an object and includes a mass at its distal end. The...
US20140035077 Photovoltaic Device Including Semiconductor Nanocrystals  
A photovoltaic device includes a semiconductor nanocrystal and a charge transporting layer that includes an inorganic material. The charge transporting layer can be a hole or electron transporting...
US20140034002 Ultra-high Efficiency Alcohol Engines Using Optimized Exhaust Heat Recovery  
Engine system using alcohol Rankine heat recovery where the engine heat converts alcohol into hydrogen-rich gas which is then introduced into the engine cylinders. The engine system includes a...
8645115 Modular nucleic acid-based circuits for counters, binary operations, memory and logic  
We have created novel engineered genetic counter designs and methods of use thereof that utilize DNA recombinases to provide modular systems, termed single invertase memory modules (SIMMs), for...
8644512 Mission planning interface for accessing vehicle resources  
In an aspect, the invention features a method for mission planning. The method includes displaying a graphical representation of a geographical area and displaying a graphical representation of one...