Patents and Patent Applications from Massachusetts Institute of Technology MIT


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US20170299566 Reagents For Oxidizer-Based Chemical Detection  
Reagents and methods are disclosed for detection of oxidizers and inorganic salts and other analytes of interest. The reagents can interact with their target analytes, especially oxidizer...
US20170299149 APPARATUS, SYSTEMS, AND METHODS OF TRANSPARENT DISPLAYS  
A transparent display includes nanoparticles having wavelength-selective scattering (e.g., resonant scattering) to preferentially scatter light at one or more discrete wavelengths so as to create...
US20170298917 Solid State Pump Using Electro-Rheological Fluid  
The systems and methods described herein are directed towards a solid state pumping system that utilizes an electric field applied across a channel formed within the solid state pump to move...
US20170298312 Methods and apparatus for shifted-wavelength photosynthetic energy harvesting and biomass production  
One or more light sources may apply stimuli to a colony of organisms. The stimuli may include visible and non-visible light. The stimuli, taken together, may tend to favor survival of organisms...
US20170298120 ANTIBODIES THAT BIND EBOLA GLYCOPROTEIN AND USES THEREOF  
Isolated monoclonal antibodies which bind to Ebola virus glycoprotein and related antibody-based compositions and molecules are disclosed. Also disclosed are therapeutic and diagnostic methods for...
US20170296732 System And Method For Inertial Focusing Microfiltration For Intra-Operative Blood Salvage Autotransfusion  
A system for intra-operative blood salvage autotransfusion is provided. The system comprises at least one inlet configured to receive whole blood of a patient; at least one curvilinear...
9793944 System and apparatus for decoding tree-based messages  
A system and techniques for decoding a message received over a communication channel comprises a receiver for receiving an encoded message. A sorting module is configured to organize candidate...
9793479 Methods for fabricating devices including photovoltaic devices  
Embodiments described herein provide methods for processing various polymer materials for use in devices, such as photovoltaic devices. In some cases, oxidative chemical vapor deposition (oCVD)...
9791394 Stable nanocrystalline ordering alloy systems and methods of identifying same  
Provided in one embodiment is a method of identifying a stable phase of an ordering binary alloy system comprising a solute element and a solvent element, the method comprising: determining at...
9791258 Methods, systems, and apparatus for programmable quantum photonic processing  
A programmable photonic integrated circuit implements arbitrary linear optics transformations in the spatial mode basis with high fidelity. Under a realistic fabrication model, we analyze...
9790549 Sieve valves, microfluidic circuits, microfluidic devices, kits, and methods for isolating an analyte  
The invention generally provides a sieve valve including: a substrate defining a channel; a flexible membrane adapted and configured for deployment at an intersection with the channel; and one or...
9790490 CRISPR enzymes and systems  
The invention provides for systems, methods, and compositions for targeting nucleic acids. In particular, the invention provides non-naturally occurring or engineered DNA or RNA-targeting systems...
9790487 Rapid assembly of multiple arbitrary length DNA fragments  
Aspects herein relate to composition, and related methods, for isolating and assembling DNA molecules without intermediate cloning steps.
9790424 Highly luminescent color-selective nanocrystalline materials  
A nanocrystal capable of light emission includes a nanoparticle having photoluminescence having quantum yields of greater than 30%.
9790188 Benzimidazole derivatives and uses thereof  
The present invention provides novel compounds of Formula (I), and pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, isotopically labeled...
9790102 Multi-stage bubble column humidifier  
A feed liquid flows into a second-stage humidifier chamber to form a second-stage humidifier bath. A first remnant of the feed liquid from the second-stage humidifier chamber then flows into a...
9789485 Micro-fluidic device and uses thereof  
A micro-fluidic device includes at least one inlet and a curvilinear microchannel having a trapezoidal cross section defined by a radially inner side, a radially outer side, a bottom side, and a...
9789256 Bi-directional motion of a lorentz-force actuated needle-free injector (NFI)  
The present invention relate to a method and corresponding apparatus for just in time mixing of a solid or powdered formulation and its subsequent delivery to a biological body. In some...
US20170295253 SYSTEMS AND METHODS FOR MANAGING DATA PROXIES  
Systems and methods are provided for managing data proxies. The systems and methods enable a proxy management system to store and manage data proxies that digitally represent real-world objects...
US20170294551 THERMO-ELECTRICALLY PUMPED LIGHT-EMITTING DIODES  
Contrary to conventional wisdom, which holds that light-emitting diodes (LEDs) should be cooled to increase efficiency, the LEDs disclosed herein are heated to increase efficiency. Heating an LED...
US20170293844 HUMAN-MACHINE COLLABORATIVE OPTIMIZATION VIA APPRENTICESHIP SCHEDULING  
Domain expert heuristics are captured within a computational framework for a task scheduling system. One or more classifiers are trained to predict (i) whether a first action should be scheduled...
US20170292104 MICROFLUIDIC SYSTEM AND METHOD FOR PERFUSION BIOREACTOR CELL RETENTION  
A microfluidic system for cell retention for a perfusion bioreactor is provided. The system comprises at least one inlet configured to receive a bioreaction mixture to be processed. At least one...
US20170291841 Methods and Apparatus for Additive Manufacturing with Molten Glass  
A nozzle deposits a filament of viscous, molten glass onto a print bed, while the print bed rotates about a vertical axis and translates in x, y, and z directions. The deposition is computer...
9786955 Assembly methods for liquid metal battery with bimetallic electrode  
Electrochemical cells operating with molten electrodes and electrolyte, where the cathode is an alloy of a metal and metalloid, may be assembled in a discharged state by combining first an anodic...
9786944 High energy density redox flow device  
Redox flow devices are described in which at least one of the positive electrode or negative electrode-active materials is a semi-solid or is a condensed ion-storing electroactive material, and in...
9786633 Interconnect structures for fine pitch assembly of semiconductor structures and related techniques  
A semiconductor structure includes a substrate having first and second opposing surfaces and a plurality of electrical connections extending between the first and second surfaces. The...
9786423 Method and apparatus for producing an asymmetric magnetic field  
A system for generating an asymmetric magnetic field. The system includes a drive circuit and a stacked winding structure coupled to the drive circuit. The stacked winding structure includes a...
9783907 Tuning nano-scale grain size distribution in multilayered alloys electrodeposited using ionic solutions, including Al—Mn and similar alloys  
Al—Mnx/Al—Mny multilayers with a wide range of structures ranging from microcrystalline to nanocrystalline and amorphous were electrodeposited using a single bath method under galvanostatic...
US20170288281 LITHIUM METAL ELECTRODES AND BATTERIES THEREOF  
The present disclosure is generally related to separators for use in lithium metal batteries, and associated systems and products. Certain embodiments are related to separators that form or are...
US20170288112 Fabrication of Stable Electrode/Diffusion Barrier Layers for Thermoelectric Filled Skutterudite Devices  
Disclosed are methods for the manufacture of n-type and p-type filled skutterudite thermoelectric legs of an electrical contact. A first material of CoSi2 and a dopant are ball-milled to form a...
US20170283831 PROTECTED GUIDE RNAS (PGRNAS)  
The invention provides for systems, methods, and compositions for altering expression of target gene sequences and related gene products. Provided are structural information on the Cas protein of...
US20170283537 Stable Polymeric Nanoparticle Compositions and Methods Related Thereto  
Disclosed are compositions comprising composite nanoparticles and a reporter molecule for use in detecting the presence of an analyte in a substrate. The composite nanoparticles comprise a solid...
US20170281542 LIPID FORMULATIONS FOR DELIVERY OF MESSENGER RNA  
The present invention provides, among other things, methods of delivering mRNA in vivo, including administering to a subject in need of delivery a composition comprising an mRNA encoding a...
US20170281059 INTRINSIC RAMAN SPECTROSCOPY  
The present invention relates to systems and methods for the measurement of analytes such as glucose. Raman and reflectance spectroscopy are used to measure a volume, of material such as a blood...
US20170281009 DIGITAL IMAGE CORRELATION FOR MEASURING SKIN STRAIN AND DEFORMATION  
Described embodiments provide a system and method for measuring surface deformation and strain using digital image correlation of a surface of a test object. A data acquisition system acquires...
9780363 High-capacity positive electrode active material  
This disclosure provides a positive electrode active lithium-excess metal oxide with composition LixMyO2 (0.6≦y≦0.85 and 0≦x+y≦2) for a lithium secondary battery with a high reversible capacity...
9780075 Interconnect structures for assembly of multi-layer semiconductor devices  
A multi-layer semiconductor device includes at least two semiconductor structures, each of the at least two semiconductor structures having first and second opposing surfaces and including a first...
9779638 Educational building blocks to model DNA and RNA structures  
A kit of educational building blocks models nucleic acid structures for use in teaching nucleic acid structures using building blocks that visually represent nucleotides and their components.
9778416 Method and structure providing a front-end-of-line and a back-end-of-line coupled waveguides  
An integrated structure and method of formation provide a lower level waveguide having a core of a first material and a higher level waveguide having a core of a second material and a coupling...
9778363 Methods and apparatus for coded time-of-flight camera  
In illustrative implementations, a time-of-flight camera robustly measures scene depths, despite multipath interference. The camera emits amplitude modulated light. An FPGA sends at least two...
9777753 Methods and apparatus for shape control  
In exemplary implementations of this invention, a shape controller controls the shape of a bladder as the bladder inflates. The shape controller includes a first set of regions and a second set of...
9777252 Modular platform for multi-tissue integrated cell culture  
The systems and methods disclosed herein are generally related to a cell culture system. More particularly, the systems and methods enable the culturing and interconnecting of a plurality of...
9777067 HER2- and VEGF-A-binding proteins with enhanced stability  
The invention provides HER2-binding proteins and VEGF-A-binding proteins having a reduced tendency to aggregate. Compositions and methods of use are also provided.
US20170280463 Cognitive Radio Method And Apparatus For Achieving Ad Hoc Interference Multiple Access Wireless Communication  
An SUOC radio employs: (1) Spectrum sensing and parameter estimation methods to characterize potential FUOCs; (2) A rate pair prediction tool to guide it's choice of FUOC to target along with the...
US20170280161 GENERATING TRANSFORMS FOR COMPRESSING AND DECOMPRESSING VISUAL DATA  
Encoding data includes: encoding a residual of a first portion of an array of data to generate a first set of coefficients; decoding the first set of coefficients to generate a decoded...
US20170278173 PERSONALIZED BUNDLE RECOMMENDATION SYSTEM AND METHOD  
An aspect of the disclosure includes a method, a system and a computer program product for determining a personalized bundle offer for a consumer. The method includes determining an interest in an...
US20170276869 METALIZED DOUBLE-CLAD OPTICAL FIBER  
Double-clad optical fibers with polymer outer coatings are used in fiber amplifiers and fiber lasers to guide and amplify light. As the optical power increases, the optical fibers must dissipate...
9772282 System for wide field-of-view, highly oblique illumination microscopy for scatter-based discrimination of cells  
System for scatter-based differentiation of cells. The system includes a planar substrate having cells disposed thereon for imaging and a microscope employing relatively low magnification...
9771386 Z-selective ring-closing metathesis reactions  
The present invention relates generally to olefin metathesis. In some embodiments, the present invention provides methods for Z-selective ring-closing metathesis.
9771264 Controlled-orientation films and nanocomposites including nanotubes or other nanostructures  
Generally, the present invention provides methods for the production of materials comprising a plurality of nanostructures such as nanotubes (e.g., carbon nanotubes) and related articles. The...