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Patents and Patent Applications from Massachusetts Institute of Technology MIT


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US20140218478 METHOD AND APPARATUS FOR STEREOSCOPIC IMAGING  
A device is disclosed that utilizes color or polarization to generate two separate images of the same object taken from the two perspectives that correspond to the left and right eyes of an...
US20140216395 FUEL MANAGEMENT SYSTEM FOR VARIABLE ETHANOL OCTANE ENHANCEMENT OF GASOLINE ENGINES  
Fuel management system for efficient operation of a spark ignition gasoline engine. Injectors inject an anti-knock agent such as ethanol directly into a cylinder of the engine. A fuel management...
8798106 Mode-locking with reduced nonlinearity using gain-matched output couplers  
A laser cavity includes a gain medium for amplifying a light pulse in a light path, wherein the gain medium has a gain profile for amplifying the light pulse as a function of wavelength; at least...
8796544 Bio-sensitized solar cells (BSSC)  
The present invention provides a wet or dry bio-sensitized photoelectric conversion device (photodetector or photovoltaic) comprising: a stabilized biologically-derived sensitizer, such as a...
8796016 RNA interference mediating small RNA molecules  
Double-stranded RNA (dsRNA) induces sequence-specific post-transcriptional gene silencing in many organisms by a process known as RNA interference (RNAi). Using a Drosophila in vitro system, we...
8795965 CRISPR-Cas component systems, methods and compositions for sequence manipulation  
The invention provides for systems, methods, and compositions for manipulation of sequences and/or activities of target sequences. Provided are vectors and vector systems, some of which encode one...
8795958 In vivo gene sensors  
Described are methods and compositions for the detection of target genes. The inventors have developed a synthetic nucleic acid sensor-effector gene circuit. In cells without a target gene, the...
8795572 Symmetric thermocentric flexure with minimal yaw error motion  
A stamping structure for imprinting micro-sized features is provided. The stamping structure includes one or more optical flats. A flexure arrangement includes a plurality of beam flexures arranged...
8795173 Methods and apparatus for assessment of atypical brain activity  
In exemplary implementations of this invention, sensor measurements are taken before, during and after an epileptiform seizure of a human. The sensors measure electrodermal activity (EDA) and heart...
US20140213919 Systems and Methods for Detecting a Physiological Abnormality in a Patient by Using Cardiac or Other Chaos in Combination with Non-increasing Parasympathetic Modulation  
A method and associated apparatus combine a calculation of chaos of a quantifiable cardiac characteristic associated with a patient with a measurement of a non-increasing parasympathetic activity...
US20140212964 MODULAR PLATFORM FOR MULTI-TISSUE INTEGRATED CELL CULTURE  
The systems and methods disclosed herein are generally related to a cell culture system. More particularly, the systems and methods enable the culturing and interconnecting of a plurality of tissue...
US20140212910 MICROGELS AND MICROTISSUES FOR USE IN TISSUE ENGINEERING  
The present invention features microgels and microtissues for use in tissue engineering. Featured is a microencapsulation device for making microgels and/or microtissues via an emulsion technology....
US20140212664 INORGANIC NANOWIRES  
Provided in one embodiment is a method of forming an inorganic nanowire, comprising: providing an elongated organic scaffold; providing a plurality of inorganic nanoparticles attached to the...
US20140212503 DELIVERY SYSTEM  
The present invention provides three-dimensional, nanoscale delivery systems, particularly well adapted for delivery of nucleic acids and/or nucleic acid associated entities.
US20140212335 MAGNETIC SEPARATION USING NANOPARTICLES  
Nanoparticles as described herein are configured to bind to bacterial contaminants, such as Gram positive bacteria, Gram negative bacteria, and endotoxins. The nanoparticles include a core...
US20140212142 UNDERWATER OPTICAL COMMUNICATION SYSTEM  
A method of optical underwater communications comprises applying a Fountain code to a plurality of data blocks. A sequence of optical data packets is transmitted through an underwater...
US20140212084 Fiber Sensor  
There is provided a sensor fiber including an electrically insulating material having a fiber length. At least one transduction element is disposed along at least a portion of the fiber length and...
US20140211881 Rateless And Rated Coding Using Spinal Codes  
In one aspect, a wireless system includes an encoder configured to encode data using a spinal code which uses a function over the message bits to directly produce a sequence of constellation...
8792786 Photonically-enabled in-flight data reorganization  
Data locality constraints are alleviated by a data processing system and method of reorganizing data. Multiple electronic components are configured to modulate a light beam on a shared photonic...
8791942 Computer method and apparatus for rotating 2D cartoons using 2.5D cartoon models  
Disclosed herein are methods, apparatus, and computer program programs that use 2D drawings of a cartoon in different views to automatically construct rotated views of the subject cartoon....
8791599 Wireless energy transfer to a moving device between high-Q resonators  
Described herein are embodiments of a first resonator with a quality factor, Q1, greater than 100, coupled to an energy source, generating an oscillating near field region, and a second resonator,...
8791411 Method and apparatus for a porous electrospray emitter  
An ionic liquid ion source can include a microfabricated body including a base and a tip. The body can be formed of a porous material compatible with at least one of an ionic liquid or...
8791092 Molecular tweezers for the treatment of amyloid-related diseases  
This invention provides novel compositions to inhibit the aggregation of amyloid proteins. In various embodiments the compositions comprise a molecular tweezers that binds lysine and/or arginine...
8790955 Methods of providing liquid material to selected regions of semiconductor material with textured surfaces  
Semiconductor photovoltaic cells have surfaces that are textured for processing and photovoltaic reasons. The absorbing regions may have parallel grooves that reduce loss of solar energy that would...
8790922 RNA sequence-specific mediators of RNA interference  
The present invention relates to a Drosophila in vitro system which was used to demonstrate that dsRNA is processed to RNA segments 21-23 nucleotides (nt) in length. Furthermore, when these 21-23...
8789458 Brewing system  
The system includes a vertically-oriented cylinder sized to receive a selected amount of water and a substance such as coffee to be brewed. A plunger is slidingly received within the cylinder. A...
US20140207431 URBAN MAPPING TECHNIQUE FOR PHOTOVOLTAIC POTENTIAL OF ROOFTOPS  
A photovoltaic map generator is provided that includes a data generator that provides LiDAR data illustrating detailed information of a geographic area. A model generator receives the LiDAR data...
US20140206860 Nanoparticle chains and Preparation Thereof  
Fabrication and arrangement of nanoparticles into one-dimensional linear chains is achieved by successive chemical reactions, each reaction adding one or more nanoparticles by building onto...
US20140206639 USES OF DIHYDRO BASES  
The present invention provides pharmaceutical compositions comprising a dihydro base described herein (e.g., compound DHdC). The dihydro base may show multiple tautomerism and may increase mutation...
US20140206603 ENGINEERED POLYPEPTIDE AGENTS FOR TARGETED BROAD SPECTRUM INFLUENZA NEUTRALIZATION  
The present invention provides novel agents for broad spectrum influenza neutralization. The present invention provides agents for inhibiting influenza infection by bind to the influenza virus...
US20140206544 RNAi-Based Method of Screening and Characterizing Drug Combinations  
In one aspect, the invention is directed to a method of characterizing a mechanism of action of a combination of agents. The method comprises contacting a plurality of populations of cells with a...
US20140206013 SPLIT PEROXIDASES AND METHODS OF USE  
An imaging method utilizing a split peroxidase is described herein. Imaging methods involve contacting a cell with a split peroxidase and a substrate thereof to allow conversion of a substrate into...
US20140205188 Sketch Recognition System  
Handwriting interpretation tools, such as optical character recognition (OCR), have improved over the years such that OCR is a common tool in business for interpreting typed text and sometimes...
US20140202780 Methods and Apparatus for Folding Vehicle Chassis  
In exemplary implementations of this invention, a foldable vehicle has a foldable chassis. The wheelbase (and thus the overall footprint) of the vehicle can be reduced when parking, and can be...
8788884 Automatic correction of program logic  
An approach to detection and repair of application level semantic errors in deployed software includes inferring aspects of correct operation of a program. For instance, a suite of examples of...
8787529 Compact coherent current and radiation source  
Coherent electronic current, which can be used to generate coherent radiation, is generated by first generating and transmitting an array of discrete electron beamlets from a nanocathode array...
8786485 Mobile coherent change detection ground penetrating radar  
Described are a method and system for detecting and locating changes in an underground region. Changes are detected using a mobile coherent change detection ground penetrating radar (GPR). The GPR...
8785881 Method and apparatus for a porous electrospray emitter  
An ionic liquid ion source can include a microfabricated body including a base and a tip. The body can be formed of a porous material compatible with at least one of an ionic liquid or...
8783871 Near eye tool for refractive assessment  
In exemplary implementations, this invention is a tool for subjective assessment of the visual acuity of a human eye. A microlens or pinhole array is placed over a high-resolution display. The eye...
8783466 Continuous biomolecule separation in a nanofilter  
This invention provides a method and an apparatus for quickly continuously fractionating biomolecules, such as DNAs, proteins and carbohydrates by taking advantage of differential bidirectional...
8783297 Robotic system for pipeline rehabilitation  
System for pipeline rehabilitation. The system includes repairing a leak in a pipe using a pair of substantially semi-cylindrical parts connected through a compliant joint. When the parts are...
US20140199746 ELECTROKINETIC CONFINEMENT OF NEURITE GROWTH FOR DYNAMICALLY CONFIGURABLE NEURAL NETWORKS  
Systems and methods for altering neurite growth are generally described. In some embodiments, a system may include a neuron comprising a neurite and electrodes able to generate a physical guidance...
US20140199745 ELECTROKINETIC CONFINEMENT OF NEURITE GROWTH FOR DYNAMICALLY CONFIGURABLE NEURAL NETWORKS  
Systems and methods for altering neurite growth are generally described. In some embodiments, a system may include a neuron comprising a neurite and electrodes able to generate a physical guidance...
US20140199229 COMPOSITIONS, METHODS, AND SYSTEMS FOR SEPARATING CARBON-BASED NANOSTRUCTURES  
The present invention generally relates to compositions, methods, and systems for separating carbon-based nanostructures.
US20140197303 FOCAL PLANE ARRAY PROCESSING METHOD AND APPARATUS  
A digital focal plane array includes an all-digital readout integrated circuit in combination with a detector array. The readout circuit includes unit cell electronics, orthogonal transfer...
US20140196498 Evaporative Heat Transfer System  
Evaporative heat transfer system. The system includes a substrate and a plurality of substantially parallel, spaced-apart ridges extending from the substrate forming vertical liquid manifolds...
8781239 Selecting transform paths for compressing visual data  
Encoding data includes: determining multiple patterns for computing one-dimensional transforms over a first array of data elements. Each pattern includes multiple subsets of data elements of the...
8780693 Coding approach for a robust and flexible communication protocol  
A coding approach for a robust and flexible network communication protocol is described. By using coding, it is possible to eliminate the need to track packet identities, and hence, it is possible...
8779198 Ring opening of lactones and lactams  
The present invention provides a novel process for opening a lactone and/or a lactam ring. More particularly, the present invention provides a process that employs a novel catalyst in the opening...
8779071 Conductive polymer films grafted on organic substrates  
One aspect of the invention relates to a linker-free, one-step method of grafting polymer films onto organic substrates, and the films obtained by such a method. In certain embodiments, the grafted...