Sign up

Patents and Patent Applications from Massachusetts Institute of Technology MIT


Match Document Document Title
8772972 Wireless energy transfer across a distance to a moving device  
Described herein are embodiments of a first resonator coupled to an energy source generating an oscillating near field region, and a second resonator optionally coupled to an energy drain and...
8772971 Wireless energy transfer across variable distances with high-Q capacitively-loaded conducting-wire loops  
Described herein are embodiments of at least one source resonator coupled to an energy source generating an oscillating near field region, and at least one device resonator optionally coupled to an...
8772693 System and method for Hilbert phase imaging  
Hilbert phase microscopy (HPM) as an optical technique for measuring high transverse resolution quantitative phase images associated with optically transparent objects. Due to its single-shot...
8772690 Multi-functional star tracker with precision focal plane position control for small cubesat-class satellites  
An optical system for use in an Earth-orbiting satellite includes a plurality of image sensors disposed on a focal plane having a reference axis orthogonal thereto, optics configured to focus...
8772197 Compositions for chemical and biological defense  
One aspect of the present invention relates to reactive compositions and methods of use thereof, wherein a metal oxide cluster is used to connect a reactive group (or groups) to the surface of a...
8771945 CRISPR-Cas systems and methods for altering expression of gene products  
The invention provides for systems, methods, and compositions for altering expression of target gene sequences and related gene products. Provided are vectors and vector systems, some of which...
8771933 Continuous-flow deformability-based cell separation  
This invention provides methods utilizing a microfluidic device that can quickly and accurately discern differences in deformability between individual cells and sets of cells and continuously...
8769712 Gravity-loading body suit  
An elastic skin suit simulates gravitational loading. By selecting material(s) of appropriate dimensions and appropriate module of elasticity, and optionally integrating inelastic portions to...
US20140187510 MOLECULAR ACTIVATORS OF THE WNT/BETA-CATENIN PATHWAY  
The present invention is directed toward a method of treating a subject for a condition mediated by aberrant Wnt/β-catenin signaling by selecting a subject with a condition mediated by aberrant ...
US20140187500 COMPOUNDS, CONJUGATES AND COMPOSITIONS OF EPIPOLYTHIODIKETOPIPERAZINES AND POLYTHIODIKETOPIPERAZINES  
The present application provides, among other things, compounds, compositions and methods for treating various diseases including cancer.
US20140186870 IN VIVO PROTEOMICS  
The application discloses methods, materials, and compositions for the labeling of molecules, for example, proteins, in living cells or in subcellular compartments of living cells. In particular,...
US20140186843 METHODS, SYSTEMS, AND APPARATUS FOR IDENTIFYING TARGET SEQUENCES FOR CAS ENZYMES OR CRISPR-CAS SYSTEMS FOR TARGET SEQUENCES AND CONVEYING RESULTS THEREOF  
Disclosed are locational or positional methods concerning CRISPR-Cas systems, and apparatus therefor.
US20140186724 MULTI-LAYER STRUCTURES PREPARED BY LAYER-BY-LAYER ASSEMBLY  
A protective layer can be deposited on a surface of an porous polymer separator placing on a Li-metal electrode to protect against adverse electrochemical activity in a battery. The protective...
US20140186620 FABRICATION AND PASSIVATION OF SILICON SURFACES  
Embodiments described herein are related to methods for processing substrates such as silicon substrates. In some cases, the method may provide the ability to passivate a silicon surface at...
US20140186312 Method Comprising Contacting Tissue With a Cross-Linkable Polyester Prepolymer  
The present inventions in various aspects provide elastic biodegradable polymers. In various embodiments, the polymers are formed by the reaction of a multifunctional alcohol or ether and a...
US20140186209 THERMOELECTRIC SKUTTERUDITE COMPOSITIONS AND METHODS FOR PRODUCING THE SAME  
Compositions related to skutterudite-based thermoelectric materials are disclosed. Such compositions can result in materials that have enhanced ZT values relative to one or more bulk materials from...
US20140185635 METHODS AND APPARATUS FOR BROADBAND FREQUENCY COMB STABILIZATION  
Feedback loops can be used to shift and stabilize the carrier-envelope phase of a frequency comb from a mode-locked fibers laser or other optical source. Compared to other frequency shifting and...
US20140185284 METHODS AND APPARATUS FOR TRANSPARENT DISPLAY USING UP-CONVERTING NANOPARTICLES  
Disclosed herein are transparent color displays with nanoparticles made with nonlinear materials and/or designed to exhibit optical resonances. These nanoparticles are embedded in or hosted on a...
US20140185282 METHODS AND APPARATUS FOR TRANSPARENT DISPLAY USING SCATTERING NANOPARTICLES  
Transparent displays enable many useful applications, including heads-up displays for cars and aircraft as well as displays on eyeglasses and glass windows. Unfortunately, transparent displays made...
US20140184273 Energy-Efficient Time-Stampless Adaptive Nonuniform Sampling  
Described herein is a sampling system and related sampling scheme. The system and sampling scheme is based upon a framework for adaptive non-uniform sampling schemes. In the system and schemes...
8766665 Reconfigurable logic automata  
A family of reconfigurable asynchronous logic elements that interact with their nearest neighbors permits reconfigurable implementation of circuits that are asynchronous at the bit level. A...
8766485 Wireless energy transfer over distances to a moving device  
Described herein are embodiments of a source resonator coupled to an energy source generating an oscillating near field region; and at least one device resonator optionally coupled to at least one...
8765930 RNA interference mediating small RNA molecules  
Double-stranded RNA (dsRNA) induces sequence-specific post-transcriptional gene silencing in many organisms by a process known as RNA interference (RNAi). Using a Drosophila in vitro system, we...
8765458 Coated sensors and methods related thereto  
The invention provides coated sensors for detecting the presence of analytes. The sensor comprises one or more fluorescent sources, such as one or more quantum dots or one or more fluorescent dyes,...
8765404 Microbial engineering for the production of fatty acids and fatty acid derivatives  
Some aspects of this invention relate to methods useful for the conversion of a carbon source to a biofuel or biofuel precursor using engineered microbes. Some aspects of this invention relate to...
8765095 Mesostructured zeolitic materials and methods of making and using the same  
One aspect of the present invention relates to mesostructured zeolites. The invention also relates to a method of preparing mesostructured zeolites, as well as using them as cracking catalysts for...
8764962 Extraction of liquid elements by electrolysis of oxides  
An electrolytic extraction method wins a target element from an oxide feedstock compound thereof. The feedstock compound is dissolved in an oxide melt in contact with a cathode and an anode in an...
8764887 Methods for electrochemically induced cathodic deposition of crystalline metal-organic frameworks  
Embodiments of the invention relate to a method for preparing crystalline metal-organic frameworks (MOFs). The method includes the steps of providing an electrolyte solution in contact with a...
8763623 Methods for handling solids in microfluidic systems  
Systems and methods related to handling solids in microfluidic systems are generally described. Many of the systems and methods described herein address the need to inhibit the formation of...
US20140181821 Methods and Systems for Enhancing Hardware Transactions Using Hardware Transactions in Software Slow-Path  
Hybrid transaction memory systems and accompanying methods. A transaction to be executed is received, and an initial attempt is made to execute the transaction in a hardware path. Upon a failure to...
US20140179770 DELIVERY, ENGINEERING AND OPTIMIZATION OF SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION AND THERAPEUTIC APPLICATIONS  
The invention provides for delivery, engineering and optimization of systems, methods, and compositions for manipulation of sequences and/or activities of target sequences. Provided are delivery...
US20140179741 USE OF CHELATORS OF DIVALENT CATIONS TO PROMOTE NERVE REGENERATION  
Disclosed herein are methods to promote axonal outgrowth of a neuron comprising, contacting the neuron with an effective amount of a chelating agent, to thereby promote axonal outgrowth in the...
US20140179006 CRISPR-CAS COMPONENT SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION  
The invention provides for systems, methods, and compositions for manipulation of sequences and/or activities of target sequences. Provided are vectors and vector systems, some of which encode one...
US20140178864 MODULAR NUCLEIC ACID-BASED CIRCUITS FOR COUNTERS, BINARY OPERATIONS, MEMORY, AND LOGIC  
We have created novel engineered genetic counter designs and methods of use thereof that utilize DNA recombinases to provide modular systems, termed single invertase memory modules (SIMMs), for...
US20140178611 APPARATUS AND METHODS EMPLOYING LIQUID-IMPREGNATED SURFACES  
In certain embodiments, the invention is directed to apparatus comprising a liquid-impregnated surface, said surface comprising an impregnating liquid and a matrix of solid features spaced...
US20140176965 THREE-DIMENSIONAL IMAGING USING A SINGLE CAMERA  
The attenuation and other optical properties of a medium are exploited to measure a thickness of the medium between a sensor and a target surface. Disclosed herein are various mediums, arrangements...
8762736 One-time programs  
A method, apparatus and computer program product for providing one-time programs is presented. A program to be converted to a new program having a predetermined lifetime is identified. The program...
8761848 Nanowire-based detector  
Systems, articles, and methods are provided related to nanowire-based detectors, which can be used for light detection in, for example, single-photon detectors. In one aspect, a variety of...
8761235 Digital transmitter  
An equalizer provided in a digital transmitter compensates for attenuation in a signal channel to a digital receiver. The equalizer generates signal levels as a logical function of bit history to...
8760008 Wireless energy transfer over variable distances between resonators of substantially similar resonant frequencies  
Described herein are embodiments of a first resonator, with a resonant frequency f1, optionally coupled to an energy source; and a second resonator, with a resonant frequency f2, optionally coupled...
8760007 Wireless energy transfer with high-Q to more than one device  
Described herein are embodiments of a source high-Q resonator, optionally coupled to an energy source, a second high-Q resonator, optionally coupled to an energy drain that may be located a...
8759876 Enhancement-mode nitride transistor  
A heterojunction for use in a transistor structure is provided. The heterojunction includes a barrier layer positioned beneath a gate region of the transistor structure. The barrier layer includes...
8759482 Kinetically efficient substrate for lipoic acid ligase  
The invention provides methods for identifying and optimizing peptide substrates for enzymes such as lipoic acid ligase (Lp1A).
8758658 System and method for uniaxial compression of an article, such as a three dimensionally printed dosage form  
A uniaxially compressed dosage form manufactured by three-dimensional printing that preserves the predetermined internal architecture of the dosage form while producing an improved surface finish....
8758271 Nonlinear system identification techniques and devices for discovering dynamic and static tissue properties  
A device for measuring a mechanical property of a tissue includes a probe configured to perturb the tissue with movement relative to a surface of the tissue, an actuator coupled to the probe to...
8758091 Chemical-mechanical polishing pad conditioning system  
Polishing pad conditioning system. The system includes a first rotatable platen supporting a polishing pad containing asperities having a radius of curvature. A second rotatable platen supports a...
8757309 Autonomous modular vehicle wheel assembly  
An autonomous modular wheel assembly includes at least one connector for connecting the wheel control assembly to a vehicle axle, one or more suspension arms that support the assembly with respect...
US20140172764 SPARSE CLASS REPRESENTATION WITH LINEAR PROGRAMMING  
A method, apparatus and computer program product for providing sparse class representation with linear programming is provided. A first model is built using a positive data set. A second model is...
US20140170753 CRISPR-CAS SYSTEMS AND METHODS FOR ALTERING EXPRESSION OF GENE PRODUCTS  
The invention provides for systems, methods, and compositions for altering expression of target gene sequences and related gene products. Provided are vectors and vector systems, some of which...
US20140170221 METHODS AND COMPOSITIONS FOR LOCALIZED DELIVERY OF AGENTS TO VIRALLY INFECTED CELLS AND TISSUES  
The invention provides compositions and methods for delivering an agent to virally infected tissues and/or cells of a subject by conjugating agent-loaded nanoparticles to virus-specific T cells,...