Patents and Patent Applications from Massachusetts Institute of Technology MIT


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9662047 Portable raman diagnostic system  
The present invention further relates to the selection of the specific filter combinations, which can provide sufficient information for multivariate calibration to extract accurate analyte...
9662014 Methods and apparatus for visual cues for eye alignment  
A retinal imaging device includes a camera, a light source, a projector, an I/O device and a computer. The projector emits two sets of light rays, such that one set of rays lies on an exterior...
US20170149104 STABLE ELECTROLYTE FOR LITHIUM AIR BATTERY AND LITHIUM AIR BATTERY INCLUDING THE SAME  
Provided are electrochemical cells that include a compound having the general formula wherein R1 is moiety associated with a lithium ion, X1 and X3 are unsubstituted methylene moieties, X2 and X4...
US20170146887 APPARATUS AND METHODS FOR GENERATING NONLINEAR EFFECTS IN CENTROSYMMETRIC MATERIALS  
A waveguide includes an array of p-i-n junctions formed by ions implanted into the waveguide. The p-i-n junctions concentrate electric fields applied on the waveguide to convert the third order...
US20170146740 WAVEGUIDE FORMATION USING CMOS FABRICATION TECHNIQUES  
Conventional approaches to integrating waveguides within standard electronic processes typically involve using a dielectric layer, such as polysilicon, single-crystalline silicon, or silicon...
US20170145694 Digital Material Assembly By Passive Means And Modular Isotropic Lattice Extruder System (MILES)  
A set of machines and related systems build structures by the additive assembly of discrete parts. These digital material assemblies constrain the constituent parts to a discrete set of possible...
US20170145061 ENGINEERED BACTEROIDES OUTER MEMBRANE VESICLES  
The present disclosure provides, in some aspects, versatile intestinal protein delivery systems deploying engineered human gut commensals of the Bacteroides species to secrete heterologous,...
US20170144828 SELF-LUBRICATING SURFACES FOR FOOD PACKAGING AND FOOD PROCESSING EQUIPMENT  
In certain embodiments, the invention relates to an article having a liquid-impregnated surface. The surface includes a matrix of solid features (e.g., non-toxic and/or edible features) spaced...
US20170144308 Self-Assembling Assemblers  
A machine that is capable of assembling a copy of itself from a feedstock of parts is described. The machine operates on a lattice or grid on which it is able to move and from which it receives...
US20170143934 SYSTEMS AND METHODS FOR PREVENTING, MITIGATING, AND/OR TREATING DEMENTIA  
The present disclosure provides systems and methods for at least one of preventing, reducing, and treating a level of or change in at least one of amyloid-β (Aβ) peptide, C-terminal fragment-β...
US20170143854 NANOPARTICLES AND METHODS OF MAKING  
Magnetic nanoparticles and synthesis of synthesis are described.
US20170143788 COMPOSITIONS AND METHODS FOR AFFECTING MOVEMENT OF CONTAMINANTS, BODILY FLUIDS OR OTHER ENTITIES, AND/OR AFFECTING OTHER PHYSIOLOGICAL CONDITIONS  
Compositions which self-assemble under physiological conditions are formulated for application to wounds. The formulations include a pharmaceutically acceptable carrier or are provided as part of...
US20170143708 COMPOUNDS, COMPOSITIONS AND METHODS OF AGELASTATIN ALKALOIDS  
The present invention, among other things, provides compounds, compositions and methods for treatment of cancer. In some embodiments, the present invention provides methods for treating blood...
US20170143196 SCANNING OPTICAL PROBE  
The invention pertains to an apparatus and methods of a medical imaging device for obtaining images from the walls of luminal organs or a surgical cavity. The invention is a rigid enclosure that...
US20170142916 Pressure Compensating Emitter Having Very Low Activation Pressure and Large Operating Range  
Pressure-compensating emitter. The emitter includes an inlet connected to a source of pressurized water and an orifice in fluid communication with the inlet and extending into a channel including...
9660520 Method and apparatus to provide power conversion with high power factor  
A power converter circuit rectifies a line voltage and applies the rectified voltage to a stack of capacitors. Voltages on the capacitors are coupled to a plurality of regulating converters to be...
9656294 Fabrication and passivation of silicon surfaces  
Embodiments described herein are related to methods for processing substrates such as silicon substrates. In some cases, the method may provide the ability to passivate a silicon surface at...
9656290 Stencil masks for making conformable electromagnetic device structures  
A new 3D stencil mask guides deposition of a shaped structure, typically an electromagnetic device component, onto a non-planar surface. The 3D stencil mask includes islands and bridges from prior...
US20170141286 MULTILOOP INTERFEROMETERS FOR QUANTUM INFORMATION PROCESSING  
Structures and techniques, using superconducting Josephson-junction based circuits, to directly engineer physical multiqubit (or “many-qubit”) interactions in a non-perturbative manner. In one...
US20170140560 Method And Apparatus For Motion Correction And Image Enhancement For Optical Coherence Tomography  
Images of an object, such as OCT scans of a human eye, can include distortions and data gaps due to relative motion of the object and the image acquisition device. Methods and systems for...
US20170140472 METHOD AND SYSTEM FOR ASSESSING AUDITING LIKELIHOOD  
A method includes mapping a first subset of integers to a plurality of transaction sequences, mapping a second subset of integers to a plurality of audit score sheets and quantitatively analyzing...
US20170140471 SYSTEM AND METHOD FOR EXTRACTING AND PROVIDING A MEASURE OF TAXABLE INCOME AND AUDIT LIKELIHOOD  
A system and method for providing a likelihood of auditing a tax return is disclosed. A population of potential solutions of transaction sequences and/or audit score sheets is initialized. Each...
US20170140414 COMPUTERIZED PROMOTION PRICE SCHEDULING UTILIZING MULTIPLE PRODUCT DEMAND MODEL  
Systems, methods, and other embodiments associated with determining a promotion price schedule for each item in a group are described. In one embodiment, a method includes computing an item...
US20170140296 PARAMAGNETIC TREE COUPLING OF SPIN QUBITS  
Described herein are structures and techniques for highly-connected qubit interaction using a “paramagnetic tree coupling” scheme. In one embodiment, a structure for providing highly-connected...
US20170139013 COMPUTING SYSTEM FOR IDENTIFICATION OF SOLID-SOLID INTERPHASE PRODUCTS  
Embodiments of a method, a system, and non-transitory computer readable storage media evaluating electrochemical qualities for interphase products. The disclosed embodiments perform a selection of...
US20170138849 SYSTEM FOR WIDE FIELD-OF-VIEW, HIGHLY OBLIQUE ILLUMINATION MICROSCOPY FOR SCATTER-BASED DISCRIMINATION OF CELLS  
System for scatter-based differentiation of cells. The system includes a planar substrate having cells disposed thereon for imaging and a microscope employing relatively low magnification...
US20170138791 Computationally-Assisted Multi-Heterodyne Spectroscopy  
According to one aspect, a multi-heterodyne system is disclosed, which comprises a first laser source for generating multi-mode radiation having a frequency spectrum characterized by a first...
US20170138735 STABLE THREE-AXIS NUCLEAR SPIN GYROSCOPE  
An n-NV-based gyroscope is provided that includes a diamond structure implanted with a plurality of NV centers, whose nuclear spins form a spin gyroscope. A number of radio-frequency (rf) coils...
US20170137858 Methods for High Fidelity Production of Long Nucleic Acid Molecules  
In a method for generating an elongated nucleic acid molecule, a nucleic acid addition of a first nucleic acid molecule attached to a first 3′ or 5′ protecting group to a nucleic acid immobilized...
US20170137768 MODULAR PLATFORM FOR TISSUE INTEGRATED CELL CULTURE  
The systems and methods disclosed herein are generally related to a cell culture system. More particularly, the systems and methods enable the culturing and interconnecting of a plurality of...
US20170136180 Stretchable, Robust and Biocompatible Hydrogel Electronics and Devices  
A tough biocompatible hydrogel having one or more drug delivery components, deformable conductors, and/or rigid electronic components incorporated therein in such a way that robust interfaces are...
US20170135954 SELF-ASSEMBLED RESIDENCE DEVICES AND RELATED METHODS  
Residence devices as well as their related methods of manufacture and use are generally provided. In some embodiments, a residence device includes a plurality of self-assembling structures that...
US20170135582 RAMAN SIGNAL MEASURING METHOD AND APPARATUS, AND BIOMETRIC INFORMATION ANALYZING APPARATUS INCLUDING THE RAMAN SIGNAL MEASURING APPARATUS  
Provided are a Raman signal measuring method and apparatus which use a difference in a time scale between Raman scattered light and fluorescence. Thus, after exciting light is incident upon a...
US20170135340 SYSTEMS AND METHODS FOR SURFACE RETENTION OF FLUIDS  
Systems and methods related to the formation of a reaction product on a surface are generally provided. The systems and methods described herein may allow for collection of the retention of a...
9650518 Liquid repellent surfaces  
A surface can be coated with a liquid repellent coating. Materials for making the liquid repellent coating (e.g., a fingerprint resistant coating) can be selected on the basis of surface energy...
9649391 Particles with multiple functionalized surface domains  
This disclosure relates to particles (e.g., nanoparticles and microparticles) that display multiple functionalized surface domains in a controlled mosaic pattern. The disclosure also provides...
9649279 Fortified micronutrient salt formulations  
Salt formulations, which are resistant to moisture and cooking conditions, are described herein. The formulations provide particles of micronutrients and vitamins encapsulated within heat...
US20170133336 INTERCONNECT STRUCTURES AND METHODS FOR FABRICATING INTERCONNECT STRUCTURES  
A method of fabricating an interconnect structure includes providing a semiconductor structure and performing a first spin resist and bake cycle. The first spin resist and bake cycle includes...
US20170131727 DYNAMIC TASK ALLOCATION IN AN AUTONOMOUS MULTI-UAV MISSION  
A mechanism for dynamically allocating tasks among multiple UAVs operating autonomously during a mission is discussed. Task assignment is adjusted by each UAV dynamically during the mission based...
US20170131287 SACCHARIDE RESPONSIVE OPTICAL NANOSENSORS  
A composition for sensing an analyte can include a photoluminescent nanostructure (e.g. a carbon nanotube) complexed to a sensing polymer, where the sensing polymer includes a phenylboronic acid...
US20170131197 FLUID ANALYSIS USING DIGITAL IMAGERY  
A system for analyzing fluid includes a housing having first and second opposing surfaces spaced to form a fluid chamber, a light source disposed to direct light at the first surface of the...
US20170131148 DETECTION OF ELECTROMAGNETIC RADIATION USING NONLINEAR MATERIALS  
An apparatus for detecting electromagnetic radiation within a target frequency range is provided. The apparatus includes a substrate and one or more resonator structures disposed on the substrate....
US20170130220 RAPID ASSEMBLY OF MULTIPLE ARBITRARY LENGTH DNA FRAGMENTS  
Aspects herein relate to composition, and related methods, for isolating and assembling DNA molecules without intermediate cloning steps.
US20170130210 DYNAMIC KNOCKDOWN OF CENTRAL METABOLISM FOR REDIRECTING GLUCOSE-6-PHOSPHATE FLUXES  
Described herein are methods for dynamic redirection of metabolic flux in a cell from central metabolism towards production of heterologous products.
US20170129911 COMPLEXES COMPRISING A PLATINUM COMPOUND AND AN IMMUNE CHECKPOINT INHIBITOR AND RELATED METHODS  
Complexes comprising a platinum compound and an immune checkpoint inhibitor, and related methods, are generally provided. In some embodiments, the immune checkpoint inhibitor is an inhibitor for...
US20170129910 Z-SELECTIVE RING-CLOSING METATHESIS REACTIONS  
The present invention relates generally to olefin metathesis. In some embodiments, the present invention provides methods for Z-selective ring-closing metathesis.
US20170128917 NOBLE METAL MONOLAYER SHELL COATINGS ON TRANSITION METAL CERAMIC NANOPARTICLE CORES  
Nanoparticles comprising a core including transition metal carbide, nitride, phosphide, sulfide, or boride and a noble metal shell can be made by transforming metal oxide core/noble metal shell...
US20170128576 ENTERIC ELASTOMERS  
Enteric elastomers and related methods are generally provided. In some embodiments, the enteric elastomer is a polymer composite. Certain embodiments comprise a polymer composite in which hydrogen...
US20170128475 COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING ORGAN INJURY AND/OR DYSFUNCTION  
The present embodiments relate to compositions and methods for treating the inflammatory response in a tissue or organ, such as the liver, by contacting the tissue with a tissue-specific gap...
US20170127983 SYSTEMS AND METHODS FOR SAMPLING CALIBRATION OF NON-INVASIVE ANALYTE MEASUREMENTS  
Systems and methods of the present invention provide a calibration model that requires minimal information compared with prior techniques. These systems and methods represent the first generalized...