Patents and Patent Applications from Massachusetts Institute of Technology MIT


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US20170074980 OBJECT TRACKING VIA RADIO REFLECTIONS  
In one aspect, a reference transmit signal is distributed to each of one or more transmit antennas, and delayed by multiple different times before transmission from the transmit antennas. The...
US20170073364 COMPOSITIONS AND METHODS COMPRISING CONDUCTIVE METAL ORGANIC FRAMEWORKS AND USES THEREOF  
Compositions and methods comprising metal organic frameworks (MOFs) and related uses are generally provided. In some embodiments, a MOF comprises a plurality of metal ions, each coordinated with...
US20170073311 SUPRAMETALLOGELS AND USES THEREOF  
The disclosure provides nanostructures (e.g., nanospheres and nano-paddlewheels) formed through transition metal-ligand (e.g., Pd(II)-, Ni(II)-, or Fe(II)-ligand of Formula (A)) coordination and...
US20170072109 SCAFFOLDS COMPRISING NANOELECTRONIC COMPONENTS FOR CELLS, TISSUES, AND OTHER APPLICATIONS  
The present invention generally relates to nanoscale wires and tissue engineering. In various embodiments, cell scaffolds for growing cells or tissues can be formed that include nanoscale wires...
US20170071937 Compositions, Systems, and Methods for Generating Inner Ear Hair Cells for Treatment of Hearing Loss  
Method and compositions for inducing the self-renewal of stem/progenitor supporting cells comprised by a cochlear cell population, including inducing the stem/progenitor cells to proliferate while...
US20170071509 SYSTEMS AND METHODS FOR DIAGNOSIS OF MIDDLE EAR CONDITIONS AND DETECTION OF ANALYTES IN THE TYMPANIC MEMBRANE  
Systems and methods are presented for the diagnosis of middle ear pathological conditions based on spectral signatures. Preferred embodiments provide for detection of one or more analytes from the...
US20170071459 LAYERED MEDIUM FOR THREE-DIMENSIONAL IMAGING  
The attenuation and other optical properties of a medium are exploited to measure a thickness of the medium between a sensor and a target surface. Disclosed herein are various mediums,...
9595920 Hardware-efficient compensator for outphasing power amplifiers  
Digital compensators for use in outphasing-based power amplification systems (e.g., Linear Amplification using Nonlinear Components (LINC) amplifiers and Asymmetric Multilevel Outphasing (AMO)...
9595893 Non-stationary multi-frequency vibration energy harvesting with tunable electrical impedance  
Harvesting energy from non-stationary, multi-frequency mechanical vibrations using a tunable electrical circuit. In an embodiment, an apparatus for converting vibrational energy to electrical...
9595682 Organic conductive materials and devices  
Embodiments described herein relate to compositions including iptycene-based structures and extended iptycene structures. In some embodiments, the compositions may be useful in organic...
9595624 Strain engineered bandgaps  
An optoelectronic device as well as its methods of use and manufacture are disclosed. In one embodiment, the optoelectronic device includes a first optoelectronic material that is inhomogeneously...
9594011 Method and instrumentation for determining a physical property of a particle  
Physical property determination of a particle or classification of the particle as a function of the physical property by evaluating scattered light profile from a single particle is disclosed....
9593139 Compositions, methods, and kits comprising platinum compounds associated with a ligand comprising a targeting moiety  
Compositions, kits, and methods for treatment of cancers are generally provided. In some embodiments, the compositions, kits, and methods comprise a platinum (e.g., Pt(II) or Pt(IV)) compound...
US20170070367 DIGITAL TRANSMITTER  
An equalizer provided in a digital transmitter compensates for attenuation in a signal channel to a digital receiver. The equalizer generates signal levels as a logical function of bit history to...
US20170070181 METALLIC DIELECTRIC PHOTONIC CRYSTALS AND METHODS OF FABRICATION  
A metallic-dielectric photonic crystal is formed with a periodic structure defining a plurality of resonant cavities to selectively absorb incident radiation. A metal layer is deposited on the...
US20170067096 Nanoscale Imaging of Proteins and Nucleic Acids via Expansion Microscopy  
The invention enables in situ genomic and transcriptomic assessment of nucleic acids to be conducted in biological specimens that have been physically expanded. The invention leverages the...
US20170066665 Ion Concentration Polarization-Electrocoagulation Hybrid Water Treatment System  
Between two juxtaposed similar ion exchange membranes (AEMs or CEMs), an ion depletion zone and ion enrichment zone are generated under an electric field. As cations are selectively transferred...
US20170065976 Atherofluidics-On-Chip  
Endothelial cells can become susceptible to disease when subjected to disturbed (atheroprone) blood flow patterns, which naturally occur in known locations in human arteries. Atheroprone flow is...
US20170065769 Injection Methods Using A Servo-Controlled Needle-Free Injector  
A method for injecting a substance through a biological body surface includes providing a needle-free transdermal transport device configured to inject the substance through the surface. The...
US20170065598 METHODS TO TREAT VISUAL IMPAIRMENT  
Amblyopia is a prevalent form of visual impairment that generally arises during infancy and early childhood when inputs to the visual cortex form the two eyes are poorly balanced. Disclosed herein...
9590278 Recycling car batteries for perovskite solar cells  
An efficient perovskite solar cells can be synthesized from used car batteries by using both the anodes and cathodes of car batteries as material sources for the synthesis of lead iodide...
9589173 Systems and methods for volumetric tissue scanning microscopy  
In accordance with preferred embodiments of the present invention, a method for imaging tissue, for example, includes the steps of mounting the tissue on a computer controlled stage of a...
9588416 Methods and apparatus for nanofabrication using a pliable membrane mask  
Apparatus for nanofabrication on an unconventional substrate including a patterned pliable membrane mechanically coupled to a membrane support structure, a substrate support structure to receive a...
9588095 Reagents for oxidizer-based chemical detection  
Reagents and methods are disclosed for detection of oxidizers and inorganic salts and other analytes of interest. The reagents can interact with their target analytes, especially oxidizer...
9588087 Continuous measurement chromatography and method of continuous stochastic perturbation chromatography  
A method and system for continuous measurement chromatograph involves stochastically modulating a system variable. The sample can be introduced into a chromatography column. The sample...
9586035 Implantable drug delivery device and methods for treatment of the bladder and other body vesicles or lumens  
An implantable medical device is provided for controlled drug delivery within the bladder, or other body vesicle. The device may include at least one drug reservoir component comprising a drug;...
9585757 Orthopaedic joints providing enhanced lubricity  
The present disclosure provides, among other things, prosthetic joint components having textured surface(s) for improving lubrication and increasing the useful life of the prosthetic joint...
US20170063043 PHOTONIC INTEGRATED CIRCUITS BASED ON QUANTUM CASCADE STRUCTURES  
Photonic integrated circuits (PICs) are based on quantum cascade (QC) structures. In embodiment methods and corresponding devices, a QC layer in a wave confinement region of an integrated...
US20170062636 GUIDED-WAVE PHOTODETECTOR APPARATUS EMPLOYING MID-BANDGAP STATES OF SEMICONDUCTOR MATERIALS, AND FABRICATION METHODS FOR SAME  
Guided-wave photodetectors based on absorption of infrared photons by mid-bandgap states in non-crystal semiconductors. In one example, a resonant guided-wave photodetector is fabricated based on...
US20170061621 SYSTEMS AND METHODS FOR TISSUE STIFFNESS MEASUREMENTS  
Automated tissue stiffness measurement devices and methods can identify cancerous lesions with high sensitivity and specificity. Systems and methods are presented to measure tissue stiffness using...
US20170061217 Combined Intensity And Coherent Change Detection In Images  
Described embodiments detect changes in a scene over time using first and second images of the scene. A non-coherent intensity change detector detects large-scale changes between the first image...
US20170059412 APPARATUS, SYSTEMS, AND METHODS FOR TALBOT SPECTROMETERS  
A non-paraxial Talbot spectrometer includes a transmission grating to receive incident light. The grating period of the transmission grating is comparable to the wavelength of interest so as to...
US20170058282 GENETICALLY ENGINEERED SENSORS FOR IN VIVO DETECTION OF BLEEDING  
Provided herein are microorganisms engineered with heme-responsive transcription factors and genetic circuits. Also provided are methods for using engineered microorganisms to sense bleeding...
US20170057823 CONTINUOUS PROCESS FOR THE PRODUCTION OF NANOSTRUCTURES INCLUDING NANOTUBES  
The present invention provides methods for uniform growth of nanostructures such as nanotubes (e.g., carbon nanotubes) on the surface of a substrate, wherein the long axes of the nanostructures...
US20170056290 Pharmaceutical Cold Box with Central Ice or Cold Pack Chamber  
Cold box. The cold box includes an enclosure comprising insulating walls having a first selected R value per surface area defining an interior space. A cold pack is located in a central region of...
US20170055875 SYSTEMS, APPARATUS, AND METHODS RELATED TO MODELING, MONITORING, AND/OR MANAGING METABOLISM  
Systems, apparatus, and methods related to modeling, monitoring, and/or managing metabolism of a subject include measuring a respiratory quotient (RQ) level in a subject and/or optimizing and...
9583779 Metal sulfide electrodes and energy storage devices thereof  
The present invention generally relates to energy storage devices, and to metal sulfide energy storage devices in particular. Some aspects of the invention relate to energy storage devices...
9580480 Cell-directed synthesis of multifunctional nanopatterns and nanomaterials  
Aspects of the invention relate to the engineering of biological nanostructures and materials.
US20170054526 Low-Delay Packet Erasure Coding  
Provided is a method for correcting errors in a data transmission network, comprising: transmitting a plurality of uncoded information packets across a network path; transmitting a plurality of...
US20170053746 PLANAR MIXED-METAL PEROVSKITES FOR OPTOELECTRONIC APPLICATIONS  
A planar mixed-metal perovskite solar cell can exhibit many favorable properties including high efficiencies and tunable electronic properties. The incorporation of different metal species (i.e....
US20170053665 ASSESSING DISORDERS THROUGH SPEECH AND A COMPUTATION MODEL  
In a system and method for assessing the condition of a subject, control parameters are derived from a neurophysiological computational model that operates on features extracted from a speech...
US20170051099 POLYMERIC MATERIALS FOR BIO-APPLICATIONS  
A composition comprising a biodegradable polymeric material and therapeutic agent associated with the polymeric material that advantageously can provide controlled release of the therapeutic...
US20170051073 CANCER-RELATED EXTRACELLULAR MATRIX SIGNATURES AND RELATED METHODS AND PRODUCTS  
Proteomic methods for identifying cancer related proteins and related products and kits are provided. The cancer specific proteins are extracellular matrix proteins that are associated with...
US20170050856 Re-Dispersible Dry Graphene Powder  
A re-dispersible, dry graphene powder can be formed by producing a solution of graphene sheets in solvent, adding surfactant to the solution, and then drying the solution to produce dry graphene...
US20170049923 Thermoreversible Hydrogels From the Arrested Phase Separation of Elastin-Like Polypeptides  
Disclosed are elastin-like polypeptides (ELPs) that form hydrogels upon heating. Hydrogels comprising the polypeptides have mechanical properties, including elastic modulus and fracture toughness,...
US20170049906 TRANSLOCATION OF NON-NATURAL CHEMICAL ENTITIES THROUGH ANTHRAX PROTECTIVE ANTIGEN PORE  
Disclosed is a new approach for delivering compounds and drugs to the cytosol of living cells through the use of engineered protein transporters. The engineered protein transporters include a pore...
US20170049882 LIPID VESICLE COMPOSITIONS AND METHODS OF USE  
The invention provides delivery systems comprised of stabilized multilamellar vesicles, as well as compositions, methods of synthesis, and methods of use thereof. The stabilized multilamellar...
US20170049793 MOLECULAR ACTIVATORS OF THE WNT/BETA-CATENIN PATHWAY  
The present invention is directed toward a method of treating a subject for a condition mediated by aberrant Wnt/β-catenin signaling by selecting a subject with a condition mediated by aberrant...
US20170049587 MODEL-BASED NEUROMECHANICAL CONTROLLER FOR A ROBOTIC LEG  
A model-based neuromechanical controller for a robotic limb having at least one joint includes a finite state machine configured to receive feedback data relating to the state of the robotic limb...
US20170049379 MRI CHARACTERIZATION OF PLACENTAL OXYGEN TRANSPORT  
A method is provided for generating images using a MRI system. The method includes one or more acts below. First, the MRI system applies a pulse sequence to obtain a first set of blood oxygenation...