Patents and Patent Applications from Massachusetts Institute of Technology MIT


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9335027 Methods and apparatus for transparent display using scattering nanoparticles  
Transparent displays enable many useful applications, including heads-up displays for cars and aircraft as well as displays on eyeglasses and glass windows. Unfortunately, transparent displays...
9334772 Particulate filter control system and method  
A system and method for controlling the operation of a particulate filter is disclosed. The objective of this control system is to manipulate the properties and spatial distribution of contaminant...
9334309 Engineered polypeptide agents for targeted broad spectrum influenza neutralization  
The present invention provides novel agents for broad spectrum influenza neutralization. The present invention provides agents for inhibiting influenza infection by bind to the influenza virus...
9333179 Amphiphilic compound assisted nanoparticles for targeted delivery  
The present invention generally relates to nanoparticles with an amphiphilic component. One aspect of the invention is directed to a method of developing nanoparticles with desired properties. In...
9333163 Particles with multiple functionalized surface domains  
This disclosure relates to particles (e.g., nanoparticles and microparticles) that display multiple functionalized surface domains in a controlled mosaic pattern. The disclosure also provides...
9333097 Artificial human limbs and joints employing actuators, springs, and variable-damper elements  
Biomimetic Hybrid Actuators employed in biologically-inspired musculoskeletal architectures employ an electric motor for supplying positive energy to and storing negative energy from an artificial...
9333060 Plaque removal and differentiation of tooth and gum  
A method of tooth treatment includes sensing a surface condition of tooth or gum and controlling ejection of a fluid jet against the tooth based on the sensed condition. The fluid may be a liquid...
9332991 Adhesive articles containing a combination of surface micropatterning and reactive chemistry and methods of making and using thereof  
Adhesive articles containing microtopography, such as microprotrusions, and a coating of adhesive glue, such an adhesive having known toxicity and/or tissue reactive functional groups are...
9332911 System and method for prediction and detection of circulatory shock  
Systems and methods for prediction and detection of circulatory shock using estimates or measurements of arterial blood pressure, heart rate, stroke volume, cardiac output, total peripheral...
US20160121546 Methods and apparatus for hygromorphic shape control  
A composite film includes a substrate that is not responsive to relative humidity, and also one or more layers of hygromorphic material. The hygromorphic material expands in response to an...
US20160121023 Materials and Methods for Rescue of Ischemic Tissue and Regeneration of Tissue Integrity During Resection, Engraftment and Transplantation  
Cell-containing implants populated with endothelial cells rescue liver donor and recipient endothelium and parenchyma from ischemic injury after major hepatectomy and engraftment. The inventions...
US20160120438 NMR SENSOR AND METHODS FOR RAPID, NON-INVASIVE DETERMINATION OF HYDRATION STATE OR VASCULAR VOLUME OF A SUBJECT  
The invention features methods for detecting the hydration state or vascular volume of a subject using a device capable of nuclear magnetic resonance (NMR) measurement. The methods involve...
9329257 Cooperative localization for wireless networks  
A system and corresponding method using a cooperative localization technique for self identifying a location of a wireless device in a wireless network is presented. The system may estimate an...
9327281 Carbon-dioxide compound and catalyst  
Tetrahedral [MoO4]2− readily binds CO2 to produce a robust [MoO3(κ2-CO3)]2− that can affect the reduction of CO2 to formate.
9327010 Compositions and methods for promoting hemostasis and other physiological activities  
Compositions that include nanoscale structured materials or precursors thereof (e.g., self-assembling peptides) are described. The compositions can include other substances (e.g., a...
US20160119798 ADAPTIVE COMMUNICATION FOR MOBILE ROUTER SYSTEMS  
An approach to adaptively positioning a set of mobile routers to provide communication services to a set of clients makes use of estimated direction profiles of communication between routers and...
US20160119287 OPTIMIZED TRANSPORT LAYER SECURITY  
A method for establishing a secure communication session over communication paths between one or more client devices and one or more server computers according to a communication protocol includes...
US20160117932 Method and Apparatus For Locating A Target Using An Autonomous Unmanned Aerial Vehicle  
Described herein is an unmanned aerial vehicle (UAV) system that incorporates sensor data to statistically minimize the time to autonomously locate a target on the ground. The system uses a...
US20160117610 TRANSPORTATION SERVICE RESERVATION METHOD, TRANSPORTATION SERVICE RESERVATION APPARATUS, AND COMPUTER-READABLE STORAGE MEDIUM  
A transportation service reservation method executes, by a computer, a process including receiving a ride request specifying an origin and a destination, generating feasible products having...
US20160116678 SYSTEMS AND METHODS FOR LASER FREQUENCY STABILIZATION USING AN ARBITRARILY BIREFRINGENT RESONATOR  
Systems and methods to stabilize a laser frequency include a birefringent resonator that introduces an arbitrary phase difference between two polarization components of the laser beam, a...
US20160116384 EXPANSION MICROSCOPY  
The present invention relates to an enlarged sample of interest for microscopy and methods for enlarging a sample of interest and the optical imaging of a sample of interest with resolution better...
US20160115489 CRISPR-CAS COMPONENT SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION  
The invention provides for systems, methods, and compositions for manipulation of sequences and/or activities of target sequences. Provided are vectors and vector systems, some of which encode one...
US20160115488 CRISPR-CAS COMPONENT SYSTEMS, METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION  
The invention provides for systems, methods, and compositions for manipulation of sequences and/or activities of target sequences. Provided are vectors and vector systems, some of which encode one...
US20160115045 PURIFICATION OF ULTRA-HIGH SALINE AND CONTAMINATED WATER BY MULTI-STAGE ION CONCENTRATION POLARIZATION (ICP) DESALINATION  
A water stream is passed between two juxtaposed similar ion exchange membranes (AEMs or CEMs), forming an ion depletion and ion enrichment zones when an electric field is applied. As cations are...
US20160114290 METHODS AND SYSTEMS FOR CARRYING OUT A PH-INFLUENCED CHEMICAL AND/OR BIOLOGICAL REACTION  
The present invention generally relates to methods and systems for carrying out a pH-influenced chemical and/or biological reaction. In some embodiments, the pH-influenced reaction involves the...
US20160114042 AMINE-CONTAINING LIPIDOIDS AND USES THEREOF  
Provided herein are lipidoids that may be prepared from the conjugate addition of alkylamines to acrylates. In some embodiments, provided lipidoids are biodegradable and may be used in a variety...
9325140 Photonic devices and methods of using and making photonic devices  
Examples of the present invention include integrated erbium-doped waveguide lasers designed for silicon photonic systems. In some examples, these lasers include laser cavities defined by...
9324486 Partial insulation superconducting magnet  
The present invention is a superconducting partial insulation magnet and a method for providing the same. The magnet includes a coil with a non-insulated superconducting wire winding wound around...
9324005 Complex-valued phase-based eulerian motion modulation  
In one embodiment, a method of amplifying temporal variation in at least two images includes converting two or more images to a transform representation. The method further includes, for each...
9321466 Controllable normal force mechanism with minimum energy consumption  
Force control system. The system includes a first pair of permanent magnets for providing a normal force on the wheel of a robot adapted for n-pipe inspections. A second pair of magnets is...
9320984 Humidification-dehumidification system with a bubble-column vapor mixture condenser and intermediate gas extraction  
A humidification-dehumidification system comprises a source of liquid; a humidifier including carrier-gas and liquid inlets and outlets and a chamber in which the liquid can contact a carrier gas...
9320751 Modified saponins for the treatment of fungal infections  
Methods of treating a fungal infection in a subject, the method comprising administering to the subject a modified saponin.
9320750 Compositions and methods of treatment of drug resistant cancers  
Time-staggered inhibition of EGFR, in combination with DNA damaging agents, is a useful therapeutic strategy for treating cancers, particularly drug resistant cancers such as a subset of...
US20160112279 Sensor-based Distributed Tangible User Interface  
A distributed tangible user interface comprises compact, self-powered, tangible user interface manipulative devices having sensing, display, and wireless communication capabilities, along with one...
US20160111242 METHOD AND APPARATUS FOR A POROUS ELECTROSPRAY EMITTER  
An ionic liquid ion source can include a microfabricated body including a base and a tip. The body can be formed of a porous material compatible with at least one of an ionic liquid or...
US20160107178 ELECTROSPRAYING SYSTEMS AND ASSOCIATED METHODS  
Electrospraying systems and associated methods are generally described.
US20160107121 Hydrophobic Air-Gap Membrane Distillation  
An energy-efficient liquid-gap distillation apparatus includes a source of a feed liquid; a distillation module comprising: (a) a feed-liquid chamber n fluid communication with the feed-liquid...
US20160106821 FUNCTIONAL GHRELIN RECEPTOR ANTAGONISM DURING PREGNANCY TO PREVENT STRESS-ASSOCIATED MENTAL ILLNESS IN OFFSPRING AND MOTHERS  
The invention relates to methods of protecting against elevated ghrelin levels in a fetus by antagonizing ghrelin or ghrelin receptor. The invention also encompasses methods of treating postpartum...
9319877 Secret key generation  
The technology includes a method for generating a secret key. The method includes receiving initialization data, the initialization data includes an initialization packet and a transmission path...
9316593 Retroreflectors for remote detection  
A detection system includes a retroreflector and a layer of material over the retroreflector, the material being subject to change in transmission with respect to an optical property of radiation,...
9315806 Massively parallel combinatorial genetics  
The invention relates to methods and compositions that enable the rapid generation of high-order combinations of genetic elements, and that provide a barcoded basis for rapid characterization of...
9315604 Metathesis catalysts and methods thereof  
The present application provides, among other things, novel compounds for metathesis reactions, and methods for preparing and using provided compounds. In some embodiments, the present invention...
9315472 1,3,5-triazinane-2,4,6-trione derivatives and uses thereof  
The present invention provides novel 1,3,5-triazinane-2,4,6-trione derivatives, such as compounds of any one of Formulae (I) and (II), and salts thereof, and methods of preparing the compounds....
US20160103951 Techniques for Controlling Spatial Structure of Nucleic Acid Structures Based on Lattice-free, Three Dimensional Junction Coordinates  
Techniques for controlling nucleic acid structures include determining, for each junction type, values for parameters indicating ground-state geometry and both translational and rotational...
US20160102332 METHODS FOR MAKING TARGETED PROTEIN TOXINS BY SORTASE-MEDIATED PROTEIN LIGATION  
We described novel methods for making targeted protein toxins by sortase-mediated protein ligation. The methods allow for a toxin and receptor-binding ligand to be ligated under mild conditions in...
US20160102118 SOLID PHASE PEPTIDES SYNTHESIS PROCESSES AND ASSOCIATED SYSTEMS  
Systems and processes for performing solid phase peptide synthesis are generally described. Solid phase peptide synthesis is a known process in which amino acid residues are added to peptides that...
US20160101594 SELF-TRANSFORMING STRUCTURES  
A self-transforming structure is formed from a flexible, fibrous composite having a weave pattern of fibers woven at intersecting angles, the weave pattern having a boundary and one or more axes...
US20160100900 ROBOTIC APPARATUS  
A robotic apparatus has eight actuators (M0-M7) and a linkage (LINK 0-LINK 5) that actuates an end effector. Three serial macro freedoms have large ranges of motion and inertias. Four serial micro...
US20160100777 INTRINSIC RAMAN SPECTROSCOPY  
The present invention relates to systems and methods for the measurement of analytes such as glucose. Raman and reflectance spectroscopy are used to measure a volume, of material such as a blood...
9313072 Integrated circuit implementation of methods and apparatuses for monitoring occupancy of wideband GHz spectrum, and sensing respective frequency components of time-varying signals using sub-nyquist criterion signal sampling  
An ASIC for monitoring wideband GHz spectrum to sense respective frequency components present in the spectrum. The ASIC implements Fast Fourier Transform (FFT) techniques to facilitate...