Patents and Patent Applications from Massachusetts Institute of Technology MIT


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9196447 Self-aligned gated emitter tip arrays  
Methods for fabrication of self-aligned gated tip arrays are described. The methods are performed on a multilayer structure that includes a substrate, an intermediate layer that includes a...
9195004 Method and apparatus for forming structures of polymer nanobeads  
The disclosure relates to providing printed structures of polymer that have substantially flat printed surfaces. In one embodiment, the disclosure relates to a post-printing treatment apparatus...
9194841 Devices and processes for analyzing nucleic acid damage and repair using electrophoresis  
Systems, methods, and devices are provided for assessing DNA damage and repair in cells by measuring DNA migration under electrophoresis. In one exemplary embodiment, a microarray configured to...
9193827 Poly(beta-amino alcohols), their preparation, and uses thereof  
A new class of poly(beta-amino alcohols) (PBAAs) has been prepared using combinatorial polymerization. The inventive PBAAs may be used in biotechnology and biomedical applications as coatings...
9193753 RNA sequence-specific mediators of RNA interference  
The present invention relates to a Drosophila in vitro system which was used to demonstrate that dsRNA is processed to RNA segments 21-23 nucleotides (nt) in length. Furthermore, when these 21-23...
US20150331232 ULTRA-FAST MECHANICAL SHUTTER  
An electro-mechanical shutter is described. The fast operation is based on a coil operated via a current, where the coil can move within a set of magnets to provide opening and closing of a...
US20150330905 Methods and apparatus for surface classification  
In illustrative implementations of this invention, light sources illuminate a surface with multi-spectral, multi-directional illumination that varies in direction, wavelength, coherence and...
US20150329590 Cysteine Arylation Directed by a Genetically Encodable Pi-Clamp  
Disclosed are methods of single-site-specific cysteine modification on peptide/protein molecules under physiologically relevant conditions. This process features several significant advantages...
US20150328838 SYSTEMS, DEVICES, AND METHODS FOR THREE-DIMENSIONAL PRINTING  
Systems, devices, and methods for three-dimensional printing are provided. The systems, devices, and methods provide for high throughput printing by allowing for parallel extrusion within a single...
US20150328378 ANTIBACTERIAL COATINGS THAT INHIBIT BIOFILM FORMATION ON IMPLANTS  
Orthopedic and dental implants coated with an antibacterial coating and methods of making and using, are described herein. The implant can be coated with a hydrophobic, polycationic antibacterial...
US20150328279 COMPOSITIONS AND METHODS FOR AFFECTING MOVEMENT OF CONTAMINANTS, BODILY FLUIDS OR OTHER ENTITIES, AND/OR AFFECTING OTHER PHYSIOLOGICAL CONDITIONS  
Compositions which self-assemble under physiological conditions are formulated for application to wounds. The formulations include a pharmaceutically acceptable carrier or are provided as part of...
9189827 Video codes for encoding/decoding streaming data  
System for conveying a stream of information. The system includes an encoding device employing a spatio-temporal coding scheme that omits light, including codes embedded therein that are invisible...
9189735 Sparse class representation with linear programming  
A method, apparatus and computer program product for providing sparse class representation with linear programming is provided. A first model is built using a positive data set. A second model is...
9189687 Assisted video surveillance of persons-of-interest  
Methods, systems and media are described for computer-assisted video surveillance. Methods may support detection of moving persons in video frames, extraction of features of the detected moving...
9189254 Translating text to, merging, and optimizing graphical user interface tasks  
A system and method that enables a plurality of lay users to collaborate on automating computer tasks is disclosed. In one embodiment, the system automatically performs these tasks, rather than...
9187983 Downhole electrical energy conversion and generation  
A procedure and device for electric energy generation from electrochemical use of substances for powering downhole devices and a procedure and device for electric energy generation from nuclear...
US20150322432 COMPOSITIONS AND METHODS FOR FUNCTIONAL NUCLEIC ACID DELIVERY  
Provided are derivatized therapeutic, prophylactic, or diagnostic agents, such as nucleic acids, that can be effectively delivered to cells and tissues. Also provided are methods of affecting a...
US20150322404 ISOLATED ADULT CELLS, ARTIFICIAL ORGANS, REHABILITATED ORGANS, RESEARCH TOOLS, ORGAN ENCASEMENTS, ORGAN PERFUSION SYSTEMS, AND METHODS FOR PREPARING AND UTILIZING THE SAME  
One aspect of the invention provides a method for harvesting adult cells from an organ. The method includes perfusing the organ with a perfusate and isolating adult cells from the organ, thereby...
US20150321921 Silica Aerogels And Their Preparation  
Silica aerogels with improved properties are disclosed together with methods for synthesizing such aerogels. The improved properties include lower thermal conductivity (better insulating...
US20150321408 CONTINUOUS FABRICATION SYSTEM AND METHOD FOR HIGHLY ALIGNED POLYMER FILMS  
Process for continuous fabrication of highly aligned polymer films. A polymer-solvent solution is subjected to a high shear, high temperature, Couette flow to extrude a thin film having polymer...
US20150321118 Multi-Stage Bubble Column Humidification and Dehumidification  
A feed liquid flows into a second-stage humidifier chamber to form a second-stage humidifier bath. A first remnant of the feed liquid from the second-stage humidifier chamber then flows into a...
US20150320837 INSULIN DERIVATIVES FOR DIABETES TREATMENT  
Compounds, compositions, and methods for “smart” delivery of a therapeutic, prophylactic or diagnostic agent, such as glucose-mediated delivery of insulin through glucose-sensing insulin...
US20150320560 RADIOLUCENT CRANIAL IMPLANTS FOR NEURAL APPLICATIONS  
Cranial implants, kits including cranial implants, and methods of making cranial implants are described. The cranial implants may be radiolucent. The cranial implants may have contact surfaces...
9185529 Wireless reliability architecture and methods using network coding  
Network-coding-enabled reliability architectures and techniques are provided that are capable of enhancing data transfer reliability and efficiency in next generation wireless networks. In some...
9181639 Continuous process for the production of nanostructures including nanotubes  
The present invention provides methods for uniform growth of nanostructures such as nanotubes (e.g., carbon nanotubes) on the surface of a substrate, wherein the long axes of the nanostructures...
9181539 Strains for the production of flavonoids from glucose  
The invention relates to the production of flavonoids and flavonoid precursors in cells through recombinant expression of tyrosine ammonia lyase (TAL), 4-coumarate:CoA ligase (4CL), chalcone...
9181297 Cysteine arylation directed by a genetically encodable π-clamp  
Disclosed are methods of single-site-specific cysteine modification on peptide/protein molecules under physiologically relevant conditions. This process features several significant advantages...
US20150319540 Method and Apparatus for Recovering Audio Signals from Images  
A method of recovering audio signals and corresponding apparatus according to an embodiment of the present invention using video or other sequence of images enables recovery of sound that causes...
US20150318360 REDUCING LEAKAGE CURRENT IN SEMICONDUCTOR DEVICES  
A semiconductor device includes a first region having a first semiconductor material and a second region having a second semiconductor material. The second region is formed over the first region....
US20150315576 GENETIC DEVICE FOR THE CONTROLLED DESTRUCTION OF DNA  
The invention relates to DNA destruction devices and related methods reagents and kits. The DNA destruction devices are useful for achieving target specific DNA destruction in vivo using a system...
US20150315574 PRODUCTION OF STABLE NON-POLYADENYLATED RNAS  
The invention relates in aspects to hybrid RNAs lacking a poly-A tail and nucleic acid vectors for expressing the RNA. The hybrid RNAs in some instances have a 3′ terminal stabilizing triple...
US20150315570 DIRECTED EVOLUTION OF SYNTHETIC GENE CLUSTER  
The invention relates to methods and products for generating diverse libraries of genetic material. The products include libraries and constructed nucleic acids as well as kits and databases and...
US20150315562 Synthetically Functionalized Living Cells  
Uniform, functional polymer patches can be attached to a fraction of the surface area of living individual cells. These surface-modified cells remain viable after attachment of the functional...
US20150315242 SELF-ASSEMBLING PEPTIDE AND PEPTIDE GEL WITH HIGH STRENGTH  
Provide are a peptide gel with practically sufficient mechanical strength and a self-assembling peptide capable of forming the peptide gel. The self-assembling peptide is formed of the following...
US20150313798 ADAPTOR FOR REMOVAL OF FLUID FROM VIAL USING A NEEDLE-FREE SYRINGE  
A needle-free adaptor for removing liquid from a vial comprises a cannula adapted to piece a septum of a vial, a plurality of legs surrounding the cannula to secure the adaptor to the vial when...
9175945 Evaluating fit of an earpiece based on dynamic data  
The attenuation and other optical properties of a medium are exploited to measure a thickness of the medium between a sensor and a target surface. Disclosed herein are various mediums,...
9173732 Medical devices for use in the surgical treatment of hyperproliferative diseases affecting the spinal cord  
Provided herein are new methods for the treatment of hyperproliferative diseases affecting the spinal cord, including the use of biodegradable polymers to treat spinal cord tumor recessing, i.e.,...
US20150311982 DEVICES AND TECHNIQUES FOR INTEGRATED OPTICAL DATA COMMUNICATION  
Devices and techniques for integrated optical data communication. An optical receiver may include a photodetector and a differential amplifier. The photodetector is coupled to an optical...
US20150311971 Method And Apparatus For Smart Adaptive Dynamic Range Multiuser Detection Radio Receiver  
A receiver includes multi-user detection (MUD) functionality and a cognitive engine. The receiver may also be coupled to multiple antennas and have analog beamforming capability. The cognitive...
US20150311664 METHOD AND APPLICATIONS OF THIN-FILM MEMBRANE TRANSFER  
The disclosure relates to method and apparatus for micro-contact printing of micro-electromechanical systems (“MEMS”) in a solvent-free environment. The disclosed embodiments enable forming a...
US20150311444 ELECTRODES FORMED BY OXIDATIVE CHEMICAL VAPOR DEPOSITION AND RELATED METHODS AND DEVICES  
The present invention generally relates to electrodes formed by oxidative chemical vapor deposition and related methods and devices.
US20150311401 THERMO-ELECTRICALLY PUMPED LIGHT-EMITTING DIODES  
Contrary to conventional wisdom, which holds that light-emitting diodes (LEDs) should be cooled to increase efficiency, the LEDs disclosed herein are heated to increase efficiency. Heating an LED...
US20150311363 NANOWIRE-MODIFIED GRAPHENE AND METHODS OF MAKING AND USING SAME  
A transparent electrode can include a graphene sheet on a substrate, a layer including a conductive polymer disposed over the graphene sheet, and a plurality of semiconducting nanowires, such as...
US20150309306 APPLICATIONS OF CONTACT-TRANSFER PRINTED MEMBRANES  
The disclosed embodiments provide sensitive pixel arrays formed using solvent-assisted or unassisted release processes. Exemplary devices include detectors arrays, tunable optical instruments,...
US20150308015 Formation of Core-Shell Fibers and Particles by Free Surface Electrospinning  
Disclosed are methods that utilize the differences in physical properties between two coating fluids to form core-shell particles or core-shell fibers by coaxial free-surface electrospinning. The...
US20150307385 Methods and apparatus for additive manufacturing of glass  
In illustrative implementations of this invention, a crucible kiln heats glass such that the glass becomes or remains molten. A nozzle extrudes the molten glass while one or more actuators actuate...
US20150306642 APPARATUS AND METHODS EMPLOYING LIQUID-IMPREGNATED SURFACES  
In certain embodiments, the invention is directed to apparatus comprising a liquid-impregnated surface, said surface comprising an impregnating liquid and a matrix of solid features spaced...
US20150306590 CARBON-DIOXIDE COMPOUND AND CATALYST  
Tetrahedral [MoO4]2− readily binds CO2 to produce a robust [MoO3(κ2-CO3)]2− that can affect the reduction of CO2 to formate.
9172090 Electrochemical device comprising lithium manganese borate compounds  
The present invention generally relates to certain lithium materials, including lithium manganese borate materials. Such materials are of interest in various applications such as energy storage....
9170200 Inflatable membrane with hazard mitigation  
Various improvements to inflatable membranes are disclosed. These improvements include, among other things, features on the membrane that can mitigate hazards such as bubble formation or...