Patents and Patent Applications from Massachusetts Institute of Technology MIT


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US20100304236 CATALYSTS AND METHODS INCLUDING STEAM REFORMING  
The present invention generally relates to catalyst compositions comprising aluminates, such as nickel aluminates, and related methods. In some embodiments, the catalyst composition may be...
US20100304163 Coatings  
A hydrophilic coating can be applied to virtually any surface to produce a long-lasting, durable antifog effect. The coating includes a molecular-level blend of hydrophilic polymers. The coating...
US20100303912 Nanocell Drug Delivery System  
Nanocells allow the sequential delivery of two different therapeutic agents with different modes of action or different pharmacokinetics. A nanocell is formed by encapsulating a nanocore with a...
US20100303723 DRUG DELIVERY SYSTEMS USING FC FRAGMENTS  
The present invention provides drug delivery systems comprising FcRn binding partners (e.g., FcRn binding partner, Fc fragment) associated with a particle or an agent to be delivered. Inventive...
US20100303672 DETERMINATION OF EXPLOSIVES INCLUDNIG RDX  
The present invention provides sensors and methods for determination of an analyte. The analytes may be determined by monitoring, for example, a change in an optical signal of an emissive material...
US20100303119 Microfluidic Lasers  
The present invention generally relates to lasers comprising fluidic channels, such as microfluidic channels. In some instances, the channel contains two or more fluids. The fluids may remain...
US20100300752 Method and apparatus for penetrating particulate substrates  
A method or corresponding apparatus in an example embodiment of the present invention relates to penetrating a particulate substrate using a compact, lightweight, low-energy, reversible, and...
7844006 Method of non-uniform doppler compensation for wideband orthogonal frequency division multiplexed signals  
Described is a method for compensation of an OFDM signal propagating through Doppler-distorted, time-varying multipath channels. The method is based on low-complexity post-FFT signal processing....
7842874 Creating music by concatenative synthesis  
Automated creation of new music by listening is disclosed. A method to create new music may comprise listening to a plurality of music, learning from the plurality of music, and performing...
7842780 Silk fibroin materials and use thereof  
The present invention provides processes for producing porous silk fibroin scaffold material. The porous silk fibroin scaffold can be used for tissue engineering. The porosity of the silk fibroin...
7842492 Compositions of and methods of using sulfatases from flavobacterium heparinum  
This invention is related, in part, to sulfatase enzymes and methods of their use.
7842352 Nanoparticle coatings and methods of making  
A surface can be treated to deposit a superhydrophilic coating on a surface that can be antireflective and antifogging. The coating can remain antireflective and antifogging for extended periods....
7841325 Fuel management system for variable ethanol octane enhancement of gasoline engines  
Fuel management system for efficient operation of a spark ignition gasoline engine. Injectors inject an anti-knock agent such as ethanol directly into a cylinder of the engine. A fuel management...
US20100298602 SYSTEMS AND METHODS FOR MICROFLUIDIC CRYSTALLIZATION  
Systems and methods for crystallization in microfluidic systems are generally described. Many applications require the collection of time-resolved data to determine advantageous conditions for...
US20100298304 DIAGNOSIS AND TREATMENT OF AUTISM SPECTRUM DISORDERS  
The invention relates to methods for diagnosis and treatment of autism spectrum disorders, particularly for autism spectrum disorders characterized by increased head size (circumference) and...
US20100298214 TREATMENT OF AUTOIMMUNE DISEASE  
The present invention provides compositions, systems, and methods for identifying a patient suffering from and/or susceptible to autoimmune disease who might be likely to respond to treatment with...
US20100297233 OSCILLATING CELL CULTURE BIOREACTOR  
Methods and devices for cell or tissue culture are provided. One aspect provides a bioreactor having a gas permeable, closed-loop chamber for cell or tissue culture, and an oscillating means for...
US20100295061 RECRYSTALLIZATION OF SEMICONDUCTOR WATERS IN A THIN FILM CAPSULE AND RELATED PROCESSES  
An original wafer, typically silicon, has the form of a desired end PV wafer. The original may be made by rapid solidification or CVD. It has small grains. It is encapsulated in a clean thin film,...
US20100294986 SUPERCRITICAL FLUID FACILITATED PARTICLE FORMATION IN MICROFLUIDIC SYSTEMS  
The use of supercritical fluids in the production of particles in microfluidic systems is generally described. Small particles with narrow particle size distributions are useful in a wide range of...
7840914 Distributing computations in a parallel processing environment  
A system comprises a plurality of computation units interconnected by an interconnection network. A method for configuring the system comprises accepting a set of instructions corresponding to a...
7840803 Authentication of integrated circuits  
A group of devices are fabricated based on a common design, each device having a corresponding plurality of measurable characteristics that is unique in the group to that device, each device having...
7840099 Ultrafast Ge/Si resonator-based modulators for optical data communications in silicon photonics  
An optical modulator structure includes at least two waveguide structures for inputting and outputting an optical signal. At least one ring resonator structure provides coupling between the at...
7839905 Carrier-envelope phase shift using linear media  
The carrier-envelope phase in a train of optical pulses is varied utilizing the dispersive properties of lossless plates while the total dispersion in transmission is maintained practically...
7838284 Measurement of concentrations and binding energetics  
Free-standing microfluidic channels are used to both transport and analyze molecules of interest. In a biochemical context, such molecules may be polypeptides, nucleic acids, or other biomolecules....
7838024 Methods and devices for the sustained release of multiple drugs  
The invention relates to an drug delivery device and a method for delivering multiple drugs over a prolonged period of time. The drug delivery device has two or more unitary segments comprising a...
US20100292836 Cellular Automotion Digital Material  
Cellular automotion digital material is useable for rapid prototyping and fabrication of continuous string conformations and two- or three-dimensional shapes through actuation of a string, surface,...
US20100292209 METHODS FOR IDENTIFYING COMPOUNDS THAT MODULATE NEUROTROPHIC FACTOR SIGNALING  
The invention relates to screening for compounds and compositions that modulate neurotrophic factor signaling as reflected by modulation of factor-induced neurite outgrowth. The compounds and...
US20100291648 Global transcription machinery engineering  
The invention relates to global transcription machinery engineering to produce altered cells having improved phenotypes.
US20100291219 METHODS AND COMPOSITIONS RELATING TO PROGENITOR CELLS  
The invention provides compositions and methods for harvesting and enriching cells such as connective tissue progenitors cells using stirred bioreactors, and in some embodiments fibrin microcarriers.
US20100290520 SELECTING TRANSFORMS FOR COMPRESSING VISUAL DATA  
Encoding data includes: computing a first set of coefficients based on a plurality of transforms each computed over a different portion of an array of data, and a second set of coefficients based...
US20100290109 UV-REFLECTIVE STRUCTURAL COLOR  
The present invention discloses a non-quarter wave multilayer structure having a plurality of alternating low index of refraction material stacks and high index of refraction material stacks. The...
US20100289359 Electropermanent Magnet-based Motors  
An electropermanent magnet-based motor includes a stator having at least one electropermanent magnet, at least one coil around the electropermanent magnet configured to pass current pulses that...
US20100288232 FUEL MANAGEMENT SYSTEM FOR VARIABLE ETHANOL OCTANE ENHANCEMENT OF GASOLINE ENGINES  
Fuel management system for enhanced operation of a spark ignition gasoline engine. Injectors inject an anti-knock agent such as ethanol directly into a cylinder. It is preferred that the direct...
7835226 Communications and power harvesting system for in-pipe wireless sensor networks  
A system or corresponding method provides for communicating data in confined waveguides containing a fluid. The system includes processing and transmitter/receiver operations at nodes in or alone...
7833189 Controlled needle-free transport  
A needle-free transdermal transport device for transferring a substance across a surface of a biological body includes a reservoir for storing the substance, a nozzle in fluid communication with...
7832488 Anchoring system and method  
An anchoring module capable of being secured within a structure includes at least one compliant ring configured to radially expand and an expandable device positioned within the compliant ring to...
US20100285081 Bactericidal Nanofibers, and Methods of Use Thereof  
One aspect of the invention relates to an antimicrobial fiber formed from an electroprocessed blend of at least one polymer, at least one antimicrobial agent, and at least one crosslinker. Another...
US20100282613 Methods for tailoring the surface topography of a nanocrystalline or amorphous metal or alloy and articles formed by such methods  
Electrochemical etching tailors topography of a nanocrystalline or amorphous metal or alloy, which may be produced by any method including, by electrochemical deposition. Common etching methods can...
7831123 Microphotonic waveguide including core/cladding interface layer  
The invention provides a waveguide with a waveguide core having longitudinal sidewall surfaces, a longitudinal top surface, and a longitudinal bottom surface that is disposed on a substrate. An...
7829035 Oxidation catalyst  
The present invention generally relates to catalyst systems and methods for oxidation of carbon monoxide. The invention involves catalyst compositions which may be advantageously altered by, for...
US20100279421 Systems and methods using photoluminescent nanostructure based hydrogels  
Systems and methods related to compositions including hydrogels and photoluminescent nanostructures are described. The compositions can undergo a change in a physical, chemical, dielectric, or...
US20100279181 SYSTEMS AND METHODS FOR THE SEPARATION OF CARBON DIOXIDE AND WATER  
Systems and methods for the separation and capture of carbon dioxide from water are generally described. In some embodiments, a vapor stream containing carbon dioxide and water is separated using a...
US20100279112 SILK FIBROIN MATERIALS AND USE THEREOF  
The present invention provides processes for producing porous silk fibroin scaffold material. The porous silk fibroin scaffold can be used for tissue engineering. The porosity of the silk fibroin...
US20100278892 HIGH AFFINITY METAL-OXIDE BINDING PEPTIDES WITH REVERSIBLE BINDING  
A dodecamer peptide, and its modified variant, having a repeating glycine-lysine sequence was created and found to bind with high affinity to oxide surfaces and certain activated polymeric...
7825543 Wireless energy transfer  
Disclosed is an apparatus for use in wireless energy transfer, which includes a first resonator structure configured to transfer energy non-radiatively with a second resonator structure over a...
7825405 Devices comprising coated semiconductor nanocrystals heterostructures  
A semiconductor nanocrystal heterostructure has a core of a first semiconductor material surrounded by an overcoating of a second semiconductor material. Upon excitation, one carrier can be...
7824912 Methods for ex vivo propagation of adult hepatic stem cells  
The present invention is directed to methods for readily propagating somatic liver stem cells. The methods comprise enhancing guanine nucleotide (GNP) biosynthesis, thereby expanding guanine...
7824602 Ceramic processing and shaped ceramic bodies  
The present invention relates to methods for the formation of ceramic bodies. Methods of the invention involve processing ceramic-forming compositions to form an integrally self-supporting or...
US20100273259 SUBSTRATES AND METHODS FOR CULTURING STEM CELLS  
The present disclosure provides a device and a cell culture system comprising a substrate that generates significant chemical ion signatures adapted for culturing stem cells. This disclosure...
US20100273220 INNATE IMMUNE SUPPRESSION ENABLES REPEATED DELIVERY OF LONG RNA MOLECULES  
The present invention relates in part to methods for suppressing the innate immune response of a cell to transfection with an exogenous nucleic acid, to methods for increasing expression of a...