Patents and Patent Applications from Louisiana State University System


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9833433 Compositions, methods of use, and methods of treatment  
Embodiments of the present disclosure provide for compositions including an antimicrobial agent, pharmaceutical compositions including the composition or pharmaceutical composition, methods of...
US20170343551 METHOD OF DIAGNOSING AND TREATING PROSTATE CANCER  
A method of diagnosing a potentially lethal prostate cancer in a patient comprising measuring one of a level of SAM Pointed Domain Containing ETS Transcription Factor (SPDEF) expression in the...
US20170340699 Adenovirus AD36 E4ORF1 Protein For Prevention and Treatment of Non-Alcoholic Fatty Liver Disease  
This invention generally relates to methods for treating or preventing the symptoms of non-alcoholic fatty liver disease, methods for reducing excessive fat from the liver, methods of improving...
US20170340600 COMPOSITIONS, METHODS OF USE, AND METHODS OF TREATMENT  
Embodiments of the present disclosure provide for compositions including an antimicrobial agent, pharmaceutical compositions including the composition or pharmaceutical composition, methods of...
US20170336586 ASYNCHRONOUS DISTRIBUTED OPTICAL MUTUAL EXCLUSION INTERCONNECT AND METHOD  
A system and method for using the system includes a first and second waveguide and optical receiver elements coupled therebetween. The optical receiver elements include a microring configured to...
US20170336318 QUANTUM DOT LIGHT EMITTING DIODES FOR MULTIPLEX GAS SENSING  
A gas detection device comprising a light emitting source including a first plurality of quantum dots of substantially discrete size and made of a semiconductor material a gas cell to contain the...
9821061 Enhanced plasmonic nanoparticles for cancer therapy and diagnostics  
One or more techniques and/or products are disclosed using a process for preparing metallic nanoparticles. Resulting nanoparticles may comprise a gold-silver-gold core-shell-shell nanoparticles....
US20170325916 OVERLOAD FAILURE REDUCING DENTAL IMPLANTS  
A dental implant comprising a base, a central shaft and a shock absorber spacing and allowing limited movement between the base and the central shaft.
US20170315133 METHOD OF DIAGNOSING AND TREATING BRAIN ENDOTHELIAL INFLAMMATION RELATED DISEASE  
The presently claimed invention relates to materials and methods for diagnosing a chronic inflammatory disease in a patient comprising testing a biological sample from the patient for a level of a...
US20170312310 USE OF NITRITE SALTS IN CHRONIC ISCHEMIA  
Methods of treating a subject who has chronic tissue ischemia are disclosed. The methods can include administering to the subject a pharmaceutical composition comprising inorganic nitrite or a...
US20170304508 THORACIC CATHETER DEVICE  
A thoracic catheter system comprises a flexible thoracic catheter for inserting into a thoracic cavity of a human. A distal end of the thoracic catheter has a plurality of apertures. A proximate...
US20170304221 CONTINUOUS LOCAL SLOW-RELEASE OF THERAPEUTICS FOR HEAD AND NECK PROBLEMS AND UPPER AERODIGESTIVE DISORDERS  
The invention features formulations for the local delivery of therapeutically effective doses of curcumin to treat head and neck disorders and upper aerodigestive disorders. Also disclosed are use...
9782744 Detection and molecular weight determination of organic vapors  
Composite films comprising an organic salt (or GUMBOS) such as 1-n-butyl-2,3-dimethylimidazolium hexafluorophosphate and a polymer such as cellulose acetate are prepared. These films are useful in...
US20170281728 METHOD FOR TREATING CANCER USING TETRADRINE  
A method of treating a cancer disease or pre-disease condition in a mammal comprising administering a first pharmaceutical composition including a therapeutically effective amount of a first...
9777309 High throughput assay for monitoring AMP production and aminoacyl-tRNA synthetase activity  
A method of conducting an enzymatic reaction assay involving adenosine 5′-monophosphate (AMP) comprising the steps of reacting one or more compounds and producing AMP, deaminating the AMP to...
US20170267814 Controlled Radical Polymerization, and Catalysts Useful Therein  
A catalyst is prepared in situ by reaction between an aryl halide and a Ni-ligand complex. The catalyst may be used to promote chain-growth polymerization of halogen-substituted Mg or Zn monomers....
US20170266275 VACCINES AGAINST GENITAL HERPES SIMPLEX INFECTIONS  
The present invention provides vaccines for treating or preventing a herpes simplex virus infection and methods of using and making the vaccine. Further provided are recombinant herpes simplex...
9765115 Inhibitors of metastasis, methods of generating such inhibitors and their therapeutic applications  
The chain of events that explains calcitonin receptor (CTR)-stimulated invasion and metastasis of prostate cancer cells was identified. The CTR-stimulated events depend on the interaction of CTR...
9763912 Compositions, methods of use, and methods of treatment  
Embodiments of the present disclosure provide for compositions including an antimicrobial agent, pharmaceutical compositions including the composition or pharmaceutical composition, methods of...
US20170260246 CARCINOMA HOMING PEPTIDE (CHP), ITS ANALOGS, AND METHODS OF USING  
A mini-peptide and its analogs have been found to target gene products to tumors. The peptide, named Carcinoma Homing Peptide (CHP), increased the tumor accumulation of the reporter gene products...
US20170258929 CANCER TREATMENT COMBINATION COMPOSITIONS, METHODS AND USES  
The invention provides combinations and formulations including a luteinizing hormone-releasing hormone (LHRH) or a LHRH analog; and curcumin or a curcumin analog. LHRH or LHRH analog can be fused...
9759652 Quantum dot light emitting diodes for multiplex gas sensing  
A gas detection device comprising a light emitting source including a first plurality of quantum dots of substantially discrete size and made of a semiconductor material a gas cell to contain the...
9758558 Whey protein isolate hydrogels and their uses  
A biodegradable hydrogel has been made based on high concentrations of whey protein isolate (WPI). WPI gels of different compositions were fabricated by thermally inducing gelation of...
US20170253622 COMPOUNDS FOR PH-CONTROLLED RELEASE OF HYDROGEN SULFIDE  
The embodiments herein generally relates to compounds and methods for releasing H2S in a pH dependent manner. In particular, the invention provides compounds of various formulations which release...
9752145 Compositions and methods for reducing C/EBP homologous protein activity in myeloid-derived suppressor cells  
Provided are compositions and methods of use thereof that modulate C/EBP homologous stress-related protein (Chop) activity in Myeloid-derived Suppressor Cells (MDSCs). Chop is a key point in the...
9745713 Device for coastal restoration  
The invention describes a system for creating portable, porous structures for restoring coastline. The invention provides for a bag with multiple longitudinal pockets. The bag is made of porous...
US20170224725 USE OF NITRITE SALTS IN TREATING TISSUE DAMAGE  
A method of treating neuropathy in a subject, the method comprising identifying a subject who has neuropathy; and administering to the subject a pharmaceutical composition comprising one of...
9725708 Methods of modulating ubiquitin ligase activity  
Methods are provided for modulating the activity of multimeric ubiquitin-protein E3 ligases including, but not limited to, E6AP ligase activities. The methods reduce the level of oligomer...
US20170216329 Ceramide-Rubusoside Nanomicelles and Their Use in Cancer Therapy  
Water-soluble, cell-permeable nanomicelles containing ceramides and a steviol glycoside, such as rubusoside, are disclosed. The ceramide-steviol glycoside complex has high water solubility, and...
US20170216221 Delivery of Bioactive, Nanoencapsulated Antioxidants  
Methods and compositions are disclosed for delivering lutein or other antioxidant to target tissues such as the eye, in bioactive form, while protecting the antioxidant from degradation. The...
9718676 Polymeric nanopillars and nanotubes, their manufacture and uses  
A method is disclosed for fabricating free-standing polymeric nanopillars or nanotubes with remarkably high aspect ratios. The nanopillars and nanotubes may be used, for example, in integrated...
9714259 Compositions and methods for improving glucose uptake  
A compound includes the structure of general Formula II, pharmaceutically acceptable salts thereof, and/or solvates thereof: wherein R1, R2, R3, are independently selected from the group...
9707185 Water-soluble nanoparticles containing water-insoluble compounds  
Nanoparticles with entrapped, nonpolar compounds are disclosed, and a method for their synthesis. The nanoparticles are readily dissolved or dispersed in water. For example, the entrapped nonpolar...
US20170196871 Therapeutic and Diagnostic Method for Ataxia-Telangiectasia  
ATM kinase is shown to regulate proteasome-mediated protein turnover through suppression of the expression of the ubiquitin-like protein ISG15 (Interferon Stimulated Gene 15). Silencing of the...
9700578 Use of nitrite salts for the treatment of cardiovascular conditions  
It has been surprisingly discovered that administration of nitrite to subjects causes a reduction in blood pressure and an increase in blood flow to tissues. The effect is particularly beneficial,...
9700525 Continuous local slow-release of therapeutics for head and neck problems and upper aerodigestive disorders  
The invention features formulations for the local delivery of therapeutically effective doses of curcumin to treat head and neck disorders and upper aerodigestive disorders. Also disclosed are use...
US20170190750 Peptide for Protection of Allergic Respiratory Disorders  
A peptide (Peptide-1) based on the C-terminal of Equine CC10 has been discovered that can be used as a vaccine to protect horses from respiratory airway obstruction (RAO), Antibodies to Peptide-1...
US20170183655 COMPOSITIONS AND USES FOR TREATMENT THEREOF  
The invention is directed generally to oligonucleotide compositions for the treatment of DNA repeat expansion diseases. The invention also relates to oligonucleotides directed to subunits of the...
US20170173127 KEXIN-DERIVED VACCINES TO PREVENT OR TREAT FUNGAL INFECTIONS  
A vaccine is disclosed that promotes CD4+ T cell-independent host defense mechanisms to defend against infection by fungi such as Pneumocystis spp. The vaccine may be used to prevent or to treat...
US20170173126 IDENTIFICATION OF PNEUMOCYSTIS ANTIGENS AND USES THEREOF  
Pneumonia due to the fungus Pneumocystis jirovecii is a life-threatening infection that occurs in immunocompromised patients. The inability to culture the organism as well as the lack of a...
9675637 Use of nitrite salts for the treatment of cardiovascular conditions  
It has been surprisingly discovered that administration of nitrite to subjects causes a reduction in blood pressure and an increase in blood flow to tissues. The effect is particularly beneficial,...
9670540 Methods and devices for DNA sequencing and molecular diagnostics  
The present invention is directed to methods for capturing, amplifying and identifying one or more of a plurality of target nucleotide sequences in a sample. The present invention is further...
US20170152439 Nanoparticles, Nanosponges, Methods of Synthesis, and Methods of Use  
Disclosed are novel metallic nanoparticles coated with a thin protective carbon shell, and three-dimensional nano-metallic sponges; methods of preparation of the nanoparticles; and uses for these...
9657077 Carcinoma homing peptide (CHP), its analogs, and methods of using  
A mini-peptide and its analogs have been found to target gene products to tumors. The peptide, named Carcinoma Homing Peptide (CHP), increased the tumor accumulation of the reporter gene products...
US20170137822 USE OF AN miRNA TO REDUCE PROLIFERATION OF A CANCER CELL  
A method is provided for decreasing at least one of the proliferation and the migration of a cancer cell comprising contacting a cancer cell with an effective amount of a pharmaceutically...
US20170137476 Chimeric Vaccine Against Fungal Infections  
Chimeric double peptide vaccines are disclosed, useful for inducing active immunity against Candida fungal infections. The chimeric peptide comprises an Fba peptide and an Met6 peptide, covalently...
US20170135304 LSUAC HI PROTEIN RICE  
According to the invention, there is provided a novel rice cultivar, designated LSUAC Hi Protein Rice. ‘LSUAC Hi Protein Rice’ has up to an average 53% improvement in protein content with levels...
9649334 Use of nitrite salts in chronic ischemia  
Methods of treating a subject who has chronic tissue ischemia are disclosed. The methods can include administering to the subject a pharmaceutical composition comprising inorganic nitrite or a...
9644072 Controlled radical polymerization, and catalysts useful therein  
A catalyst is prepared in situ by reaction between an aryl halide and a Ni(0) complex. The catalyst may be used to promote chain-growth polymerization of halogen-substituted Mg or Zn monomers by a...
9642819 Low dosage serotonin 5-HT2A receptor agonist to suppress inflammation  
The present invention is directed to a method for the treatment of an inflammatory disorder in a mammal, said method comprising administering to a mammal in need of such treatment a...