Patents and Patent Applications from Louisiana State University System


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9994585 Transplantation therapies  
Embodiments of the present invention are directed to methods and dosage forms for treating inflammation and rejection in transplantation injuries with Bryostatin-1, Bryostatin-1 analogs and...
US20180155726 USE OF AN miRNA TO REDUCE PROLIFERATION OF A CANCER CELL  
A method is provided for decreasing at least one of the proliferation and the migration of a cancer cell comprising contacting a cancer cell with an effective amount of a pharmaceutically...
US20180155353 Antimicrobial Compounds and Methods  
Antimicrobial compounds are provided that are polymerizable. The compounds include monomers with antimicrobial properties. The compounds have cross-linking properties. The compounds may be...
9988438 Anti-HIV dual specificity antibodies and methods of HIV treatment  
Dual variable domain immunoglobulins (DVD Igs) are provided capable of tetravalent binding to bispecific sites of the human immunodeficiency virus (HIV). The DVD Igs may be asymmetric and may have...
9987286 Compositions and methods for the treatment of addiction, psychiatric disorders, and neurodegenerative disease  
The present invention features, inter alia, pharmaceutically acceptable compositions that include metyrapol as the sole pharmaceutically active agent; compositions that include metyrapol and at...
US20180149004 SINGLE-WELL GAS-ASSISTED GRAVITY DRAINAGE PROCESS FOR OIL RECOVERY  
Disclosed is a less expensive, more efficient process for enhanced oil recovery, particularly useful in high cost environments such as offshore. This process is known as single well gas assisted...
US20180142474 Sandwich Panel with a Ductile Hybrid Core Comprising Tubular Reinforcements  
A hybrid core comprising a matrix and tubular structural reinforcements, such as a ductile matrix core reinforced with ductile hollow tubes, as well as panels which comprise such hybrid core....
9977206 Asynchronous distributed optical mutual exclusion interconnect and method  
A system and method for using the system includes a first and second waveguide and optical receiver elements coupled therebetween. The optical receiver elements include a microring configured to...
US20180133318 ENHANCED PLASMONIC NANOPARTICLES FOR CANCER THERAPY AND DIAGNOSTICS  
One or more techniques and/or products are disclosed using a process for preparing metallic nanoparticles. Resulting nanoparticles may comprise a gold-silver-gold core-shell-shell nanoparticles....
US20180133262 METHODS OF TREATING NEURODEGENERATIVE DISORDERS  
A method of treating a mammal with one of a central nervous system injury and a neurodegenerative disorder comprising isolating, culturing, and generating neural progenitor cells from a mammalian...
US20180133208 CANCER TREATMENT VIA REPOSITIONED TRICYCLIC ANTI-DEPRESSANT-LIKE DRUGS AS ANTI-CANCER AGENTS AND NEW COMBINATIONS OF SUCH DRUGS  
Methods and compositions for treating a lysosomal movement associated disease in an animal, in which the position of lysosomes can influence disease progression, comprising administering an...
US20180120334 COMPOSITIONS AND METHODS FOR DETECTING PROTEINOPATHIES  
This invention is directed to compositions and methods for detecting proteinopathies.
US20180116086 Sweetpotato plant named 'V12B.445'  
A new variety of sweetpotato, identified as ‘V12B.445’, is disclosed having disease resistance to both fusarium wilt and Streptomyces soil rot; an orange flesh and purple-red skin, and high yield...
US20180104251 COMPOSITIONS AND METHODS FOR THE TREATMENT OF GLIOBLASTOMA  
Provided are compositions that include a platelet-activating factor antagonist, pharmaceutical compositions including the platelet-activating factor antagonist, methods of treating a modulating...
9937260 Curcumin conjugates for treating and preventing cancers  
Conjugating LHRH to curcumin (LHRH-Curcumin) substantially enhances the bioavailability of curcumin, targets it to cells expressing LHRH receptors, facilitates intravenous administration, and...
US20180086827 THERAPEUTICS AND METHODS OF TREATING FIBROPROLIFERATIVE DISEASES  
A method of treating a condition in a mammal comprising: administering a pharmacologically effective amount of a therapeutic; wherein the therapeutic one of decreases EphA2 expression and inhibits...
US20180085443 VACCINATION WITH ANTI-TICK ANTIGENS TO CONTROL MULTIPLE TICK SPECIES AND DISEASE TRANSMISSION IN WHITE-TAILED DEER AND OTHER HOST ANIMALS  
Compositions of either the Rm86Texas protein from a Texas outbreak strain of the southern cattle fever tick, Rhipicephalus microplus, or a nucleic acid construct incorporating a nucleic acid...
US20180085415 METHOD OF TREATING MACROPHAGE FOAM CELL FORMATION AND DISEASES ASSOCIATED WITH MACROPHAGE FOAM CELL FORMATION  
Products and methods of treating a foam cell associated disease comprising administering a pharmaceutical composition including a therapeutically effective amount of a first therapeutic; wherein...
9920062 Antimicrobial monomers and polymers, and their use in dental devices  
Antimicrobial compounds are provided that are polymerizable. The compounds include monomers with antimicrobial properties. The compounds have cross-linking properties and are hydrolytically...
US20180074039 UNIVERSAL MOLECULAR PROCESSOR FOR PRECISION MEDICINE  
The present invention is directed to a device that comprises a biomolecular processor and one or more nanotubes. Each biomolecular processor comprises a bioreactor chamber defined by a solid...
US20180072675 ANTIMICROBIAL PYRIDINOHYDRAZIDE AND HYDRAZOMETHYLPYRIDINE-BASED AGENTS  
A class of modified salicylaldehyde derivatives has also been synthesized and a series of modified pyridine-based hydrazones identified that have potent antimicrobial activity against multiple...
9909173 Biomolecular processing platform and uses thereof  
The present invention relates to a device comprising a biomolecular processor. Each biomolecular processor has one or more bioreactor chambers defined by a solid substrate; a support structure...
US20180057634 METHODS OF MAKING POLYPEPTIDES  
Various embodiments disclosed relate to a method of forming a polypeptide. The method includes contacting a first amino acid-derived N-thiocarboxyanhydrosulfide monomer as a crystalline solid with...
US20180055848 Combination of Albuterol and Caffeine as Synergistic Treatment for Obesity or Sarcopenia  
A combination of albuterol and caffeine can be used to reduce fat body mass or to increase lean body mass. The combination may be used to treat conditions such as obesity or sarcopenia. There is a...
US20180055791 LOW DOSAGE SEROTONIN 5-HT2A RECEPTOR AGONIST TO SUPPRESS INFLAMMATION  
Activation of 5-HT2A receptors using agonists at surprisingly low concentrations was shown to potently inhibit TNF-α-induced inflammation in multiple cell types. Significantly, proinflammatory...
US20180051289 THERAPEUTICS AND METHODS OF TREATING FATTY LIVER DISEASE  
A method of treating a condition in a mammal comprising administering a pharmacologically effective amount of a therapeutic, wherein the therapeutic one of increases EphA2 expression and...
US20180044278 COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF INFLAMMATORY, DEGENERATIVE, AND NEURODEGENERATIVE DISEASES  
This disclosure provides compounds, pharmaceutical compositions, and methods of use for the prevention and treatment of inflammatory diseases or degenerative diseases including neurodegenerative...
9891006 Metal-based microchannel heat exchangers made by molding replication and assembly  
Compression molding of metals is used to make microchannel heat exchangers. Heat transfer can be improved by employing controlled microchannel surface roughness. Flux-free bonding is achieved...
9888637 LSUAC Hi Protein Rice  
According to the invention, there is provided a novel rice cultivar, designated LSUAC Hi Protein Rice. ‘LSUAC Hi Protein Rice’ has up to an average 53% improvement in protein content with levels...
US20180037803 METHODS OF TREATING OIL AND GAS WELL FRACTURES  
Embodiments of the present disclosure provide for loss circulation materials, methods of making loss circulation materials, methods treating oil and gas well fractures using loss circulation...
US20180036270 A METHOD OF PROTECTING AGAINST CARBONYL STRESS INDUCED ISCHEMIA-REPERFUSION INJURY IN THE DIABETIC BRAIN VIA ADMINISTRATION OF N-ACETYLCYSTEINE  
A method for one of preventing and minimizing diabetes pathology in a mammal, comprising administering to the mammal an effective amount of N-acetylcysteine (NAC).
US20180030417 METHOD OF ALTERING EXPRESSION OF ALTERNATIVE VIRAL GLYCOPROTEIN COMPLEXES  
A method of preparing a vaccine for immunization against a herpes virus comprising the steps of one of deleting, substituting, or modifying a UL148 gene and interfering with or modifying an...
US20180028471 CONTINUOUS LOCAL SLOW-RELEASE OF THERAPEUTICS FOR HEAD AND NECK PROBLEMS AND UPPER AERODIGESTIVE DISORDERS  
The invention features formulations for the local delivery of therapeutically effective doses of curcumin to treat head and neck disorders and upper aerodigestive disorders. Also disclosed are...
US20180026201 CARBAZOLE-BASED GUMBOS FOR HIGHLY EFFICIENT BLUE OLEDS  
Various examples are provided for carbazole-based GUMBOS (group of uniform materials based on organic salts), and its application in organic light emitting diodes (OLEDs). In one example, a...
US20180021411 Composition and Method for Improving Sleep Duration and Quality  
An intervention for sleep disorders comprises: collagen, a gelatin peptide, or the amino acid glycine; L-theanine; lactucopicrin, deoxylactucopicrin, or another lactucopicrin derivative;...
9872760 Soft tissue tensioning and fixation device  
An improved device provides a cost-effective, time-effective way to stably and reliably affix soft tissues (e.g., tendon or ligament) to the surface of anatomical structures with comparable or...
US20180016162 Magnetic Metal Oxide Biochar Composite Particles, and Their Use in Recovering Pollutants From Aqueous Solution  
Composite particles are disclosed comprising magnesium oxide, iron oxide, and biochar; and methods of making and using the composite particles. The composite particles may be used to recover...
US20180006257 CARBON DOT MULTICOLOR PHOSPHORS  
Carbon dots synthesized from p-phenylenediamine in diphenyl ether exhibit excitation wavelength independent long wavelength multicolor emissions (green to red) when they are dispersed in different...
US20180003735 TIP ENHANCED LASER ASSISTED SAMPLE TRANSFER FOR BIOMOLECULE MASS SPECTROMETRY  
Disclosed are various embodiments for transferring molecules from a surface for mass spectrometry and other sample analysis methods, and the like. A laser is focused onto a tip of an atomic force...
9850660 Sandwich panel with a ductile hybrid core comprising tubular reinforcements  
A hybrid core comprising a matrix and tubular structural reinforcements, such as a ductile matrix core reinforced with ductile hollow tubes, as well as panels which comprise such hybrid core....
US20170362500 SHAPE MEMORY POLYMER PROPPANTS, METHODS OF MAKING SHAPE MEMORY POLYMER PROPPANTS FOR APPLICATION IN HYDRAULIC FRACTURING TREATMENTS  
The present disclosure provides for shape memory proppants, methods for making shape memory proppants, and methods of using shape memory proppants, and the like. The strong expandable proppants of...
9833433 Compositions, methods of use, and methods of treatment  
Embodiments of the present disclosure provide for compositions including an antimicrobial agent, pharmaceutical compositions including the composition or pharmaceutical composition, methods of...
US20170343551 METHOD OF DIAGNOSING AND TREATING PROSTATE CANCER  
A method of diagnosing a potentially lethal prostate cancer in a patient comprising measuring one of a level of SAM Pointed Domain Containing ETS Transcription Factor (SPDEF) expression in the...
US20170340699 Adenovirus AD36 E4ORF1 Protein For Prevention and Treatment of Non-Alcoholic Fatty Liver Disease  
This invention generally relates to methods for treating or preventing the symptoms of non-alcoholic fatty liver disease, methods for reducing excessive fat from the liver, methods of improving...
US20170340600 COMPOSITIONS, METHODS OF USE, AND METHODS OF TREATMENT  
Embodiments of the present disclosure provide for compositions including an antimicrobial agent, pharmaceutical compositions including the composition or pharmaceutical composition, methods of...
US20170336586 ASYNCHRONOUS DISTRIBUTED OPTICAL MUTUAL EXCLUSION INTERCONNECT AND METHOD  
A system and method for using the system includes a first and second waveguide and optical receiver elements coupled therebetween. The optical receiver elements include a microring configured to...
US20170336318 QUANTUM DOT LIGHT EMITTING DIODES FOR MULTIPLEX GAS SENSING  
A gas detection device comprising a light emitting source including a first plurality of quantum dots of substantially discrete size and made of a semiconductor material a gas cell to contain the...
9821061 Enhanced plasmonic nanoparticles for cancer therapy and diagnostics  
One or more techniques and/or products are disclosed using a process for preparing metallic nanoparticles. Resulting nanoparticles may comprise a gold-silver-gold core-shell-shell nanoparticles....
US20170325916 OVERLOAD FAILURE REDUCING DENTAL IMPLANTS  
A dental implant comprising a base, a central shaft and a shock absorber spacing and allowing limited movement between the base and the central shaft.
US20170315133 METHOD OF DIAGNOSING AND TREATING BRAIN ENDOTHELIAL INFLAMMATION RELATED DISEASE  
The presently claimed invention relates to materials and methods for diagnosing a chronic inflammatory disease in a patient comprising testing a biological sample from the patient for a level of a...