Patents and Patent Applications from Louisiana State University System


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9782744 Detection and molecular weight determination of organic vapors  
Composite films comprising an organic salt (or GUMBOS) such as 1-n-butyl-2,3-dimethylimidazolium hexafluorophosphate and a polymer such as cellulose acetate are prepared. These films are useful in...
US20170281728 METHOD FOR TREATING CANCER USING TETRADRINE  
A method of treating a cancer disease or pre-disease condition in a mammal comprising administering a first pharmaceutical composition including a therapeutically effective amount of a first...
9777309 High throughput assay for monitoring AMP production and aminoacyl-tRNA synthetase activity  
A method of conducting an enzymatic reaction assay involving adenosine 5′-monophosphate (AMP) comprising the steps of reacting one or more compounds and producing AMP, deaminating the AMP to...
US20170275661 PROCESS FOR THE PRODUCTION OF ISOMALTOOLIGOSACCHARIDES  
The present invention provides a method for the production of oligosaccharides by the fermentation of dextran-sucrase-producing microorganisms with sucrose and maltose. The disclosed process...
US20170267814 Controlled Radical Polymerization, and Catalysts Useful Therein  
A catalyst is prepared in situ by reaction between an aryl halide and a Ni-ligand complex. The catalyst may be used to promote chain-growth polymerization of halogen-substituted Mg or Zn monomers....
US20170266275 VACCINES AGAINST GENITAL HERPES SIMPLEX INFECTIONS  
The present invention provides vaccines for treating or preventing a herpes simplex virus infection and methods of using and making the vaccine. Further provided are recombinant herpes simplex...
9765115 Inhibitors of metastasis, methods of generating such inhibitors and their therapeutic applications  
The chain of events that explains calcitonin receptor (CTR)-stimulated invasion and metastasis of prostate cancer cells was identified. The CTR-stimulated events depend on the interaction of CTR...
9763912 Compositions, methods of use, and methods of treatment  
Embodiments of the present disclosure provide for compositions including an antimicrobial agent, pharmaceutical compositions including the composition or pharmaceutical composition, methods of...
US20170260246 CARCINOMA HOMING PEPTIDE (CHP), ITS ANALOGS, AND METHODS OF USING  
A mini-peptide and its analogs have been found to target gene products to tumors. The peptide, named Carcinoma Homing Peptide (CHP), increased the tumor accumulation of the reporter gene products...
US20170258929 CANCER TREATMENT COMBINATION COMPOSITIONS, METHODS AND USES  
The invention provides combinations and formulations including a luteinizing hormone-releasing hormone (LHRH) or a LHRH analog; and curcumin or a curcumin analog. LHRH or LHRH analog can be fused...
9759652 Quantum dot light emitting diodes for multiplex gas sensing  
A gas detection device comprising a light emitting source including a first plurality of quantum dots of substantially discrete size and made of a semiconductor material a gas cell to contain the...
9758558 Whey protein isolate hydrogels and their uses  
A biodegradable hydrogel has been made based on high concentrations of whey protein isolate (WPI). WPI gels of different compositions were fabricated by thermally inducing gelation of...
US20170253622 COMPOUNDS FOR PH-CONTROLLED RELEASE OF HYDROGEN SULFIDE  
The embodiments herein generally relates to compounds and methods for releasing H2S in a pH dependent manner. In particular, the invention provides compounds of various formulations which release...
9752145 Compositions and methods for reducing C/EBP homologous protein activity in myeloid-derived suppressor cells  
Provided are compositions and methods of use thereof that modulate C/EBP homologous stress-related protein (Chop) activity in Myeloid-derived Suppressor Cells (MDSCs). Chop is a key point in the...
9745713 Device for coastal restoration  
The invention describes a system for creating portable, porous structures for restoring coastline. The invention provides for a bag with multiple longitudinal pockets. The bag is made of porous...
US20170224725 USE OF NITRITE SALTS IN TREATING TISSUE DAMAGE  
A method of treating neuropathy in a subject, the method comprising identifying a subject who has neuropathy; and administering to the subject a pharmaceutical composition comprising one of...
9725708 Methods of modulating ubiquitin ligase activity  
Methods are provided for modulating the activity of multimeric ubiquitin-protein E3 ligases including, but not limited to, E6AP ligase activities. The methods reduce the level of oligomer...
US20170216329 Ceramide-Rubusoside Nanomicelles and Their Use in Cancer Therapy  
Water-soluble, cell-permeable nanomicelles containing ceramides and a steviol glycoside, such as rubusoside, are disclosed. The ceramide-steviol glycoside complex has high water solubility, and...
US20170216221 Delivery of Bioactive, Nanoencapsulated Antioxidants  
Methods and compositions are disclosed for delivering lutein or other antioxidant to target tissues such as the eye, in bioactive form, while protecting the antioxidant from degradation. The...
9718676 Polymeric nanopillars and nanotubes, their manufacture and uses  
A method is disclosed for fabricating free-standing polymeric nanopillars or nanotubes with remarkably high aspect ratios. The nanopillars and nanotubes may be used, for example, in integrated...
9714259 Compositions and methods for improving glucose uptake  
A compound includes the structure of general Formula II, pharmaceutically acceptable salts thereof, and/or solvates thereof: wherein R1, R2, R3, are independently selected from the group...
9707185 Water-soluble nanoparticles containing water-insoluble compounds  
Nanoparticles with entrapped, nonpolar compounds are disclosed, and a method for their synthesis. The nanoparticles are readily dissolved or dispersed in water. For example, the entrapped nonpolar...
US20170196871 Therapeutic and Diagnostic Method for Ataxia-Telangiectasia  
ATM kinase is shown to regulate proteasome-mediated protein turnover through suppression of the expression of the ubiquitin-like protein ISG15 (Interferon Stimulated Gene 15). Silencing of the...
9700578 Use of nitrite salts for the treatment of cardiovascular conditions  
It has been surprisingly discovered that administration of nitrite to subjects causes a reduction in blood pressure and an increase in blood flow to tissues. The effect is particularly beneficial,...
9700525 Continuous local slow-release of therapeutics for head and neck problems and upper aerodigestive disorders  
The invention features formulations for the local delivery of therapeutically effective doses of curcumin to treat head and neck disorders and upper aerodigestive disorders. Also disclosed are use...
US20170190750 Peptide for Protection of Allergic Respiratory Disorders  
A peptide (Peptide-1) based on the C-terminal of Equine CC10 has been discovered that can be used as a vaccine to protect horses from respiratory airway obstruction (RAO), Antibodies to Peptide-1...
US20170183655 COMPOSITIONS AND USES FOR TREATMENT THEREOF  
The invention is directed generally to oligonucleotide compositions for the treatment of DNA repeat expansion diseases. The invention also relates to oligonucleotides directed to subunits of the...
US20170173127 KEXIN-DERIVED VACCINES TO PREVENT OR TREAT FUNGAL INFECTIONS  
A vaccine is disclosed that promotes CD4+ T cell-independent host defense mechanisms to defend against infection by fungi such as Pneumocystis spp. The vaccine may be used to prevent or to treat...
US20170173126 IDENTIFICATION OF PNEUMOCYSTIS ANTIGENS AND USES THEREOF  
Pneumonia due to the fungus Pneumocystis jirovecii is a life-threatening infection that occurs in immunocompromised patients. The inability to culture the organism as well as the lack of a...
9675637 Use of nitrite salts for the treatment of cardiovascular conditions  
It has been surprisingly discovered that administration of nitrite to subjects causes a reduction in blood pressure and an increase in blood flow to tissues. The effect is particularly beneficial,...
9670540 Methods and devices for DNA sequencing and molecular diagnostics  
The present invention is directed to methods for capturing, amplifying and identifying one or more of a plurality of target nucleotide sequences in a sample. The present invention is further...
US20170152439 Nanoparticles, Nanosponges, Methods of Synthesis, and Methods of Use  
Disclosed are novel metallic nanoparticles coated with a thin protective carbon shell, and three-dimensional nano-metallic sponges; methods of preparation of the nanoparticles; and uses for these...
9657077 Carcinoma homing peptide (CHP), its analogs, and methods of using  
A mini-peptide and its analogs have been found to target gene products to tumors. The peptide, named Carcinoma Homing Peptide (CHP), increased the tumor accumulation of the reporter gene products...
US20170137822 USE OF AN miRNA TO REDUCE PROLIFERATION OF A CANCER CELL  
A method is provided for decreasing at least one of the proliferation and the migration of a cancer cell comprising contacting a cancer cell with an effective amount of a pharmaceutically...
US20170137476 Chimeric Vaccine Against Fungal Infections  
Chimeric double peptide vaccines are disclosed, useful for inducing active immunity against Candida fungal infections. The chimeric peptide comprises an Fba peptide and an Met6 peptide, covalently...
US20170135304 LSUAC HI PROTEIN RICE  
According to the invention, there is provided a novel rice cultivar, designated LSUAC Hi Protein Rice. ‘LSUAC Hi Protein Rice’ has up to an average 53% improvement in protein content with levels...
9649334 Use of nitrite salts in chronic ischemia  
Methods of treating a subject who has chronic tissue ischemia are disclosed. The methods can include administering to the subject a pharmaceutical composition comprising inorganic nitrite or a...
9644072 Controlled radical polymerization, and catalysts useful therein  
A catalyst is prepared in situ by reaction between an aryl halide and a Ni(0) complex. The catalyst may be used to promote chain-growth polymerization of halogen-substituted Mg or Zn monomers by a...
9642819 Low dosage serotonin 5-HT2A receptor agonist to suppress inflammation  
The present invention is directed to a method for the treatment of an inflammatory disorder in a mammal, said method comprising administering to a mammal in need of such treatment a...
US20170121591 SHAPE MEMORY POLYMER PROPPANTS, METHODS OF MAKING SHAPE MEMORY POLYMER PROPPANTS FOR APPLICATION IN HYDRAULIC FRACTURING TREATMENTS  
The present disclosure provides for shape memory proppants, methods for making shape memory proppants, and methods of using shape memory proppants, and the like. The strong expandable proppants of...
US20170088829 D-STEREOSPECIFIC AMINOACYL-TRNA SYNTHETASE AND METHOD OF PRODUCING D-STEREOSPECIFIC AMINOACYL-TRNA SYNTHETASE  
A method for one of altering and enhancing the stereospecificity of an enzyme comprising introducing a stereospecific editing domain into the enzyme.
US20170088466 Self-Healing Composite of Thermoset Polymer and Programmed Super Contraction Fibers  
A composition comprising thermoset polymer, shape memory polymer to facilitate macro scale damage closure, and a means for molecular scale healing is disclosed; the composition has the ability to...
US20170087180 METHODS AND COMPOSITIONS FOR TREATING NITRIC OXIDE DEFICIENCY DISORDERS AND RELATED CONDITIONS  
The present invention relates to sulfur compositions which are useful, for example, for treating a NO deficiency disorder, supplementing deficits in circulating nitrite, and/or improving bodily...
9599626 Therapeutic and diagnostic method for ataxia-telangiectasia  
ATM kinase is shown to regulate proteasome-mediated protein turnover through suppression of the expression of the ubiquitin-like protein ISG15 (Interferon Stimulated Gene 15). Silencing of the...
9599602 Plasma H2S levels as biomarkers for vascular disease  
Hydrogen sulfide (H2S) levels in plasma are useful in diagnosing cardiovascular disease. The ratio of H2S to NO in plasma is useful in diagnosing peripheral artery disease.
9599228 Cooled seal  
Seals having incorporated heat pipes are disclosed relating to pumps and other comparable sealing equipment that may include a seal face, a cavity, a wicking material within the cavity, and a...
US20170074635 APPARATUS AND METHOD FOR NANOCOMPOSITE SENSORS  
A sensing material for use in a sensor is disclosed. Such a sensing material includes a polymer base and a piezoresistive nanocomposite embedded into the polymer base in a continuous pattern. The...
US20170073639 METHODS OF DIFFERENTIATING PREADIPOCYTES AND USES THEREOF  
Described herein are methods of transdifferentiating preadipocytes, populations of transdifferentiated preadipocytes, and methods of using the transdifferentiated preadipocytes.
9580704 Kexin-derived vaccines to prevent or treat fungal infections  
A vaccine is disclosed that promotes CD4+ T cell-independent host defense mechanisms to defend against infection by fungi such as Pneumocystis spp. The vaccine may be used to prevent or to treat...
9579344 Use of nitrite salts in treating tissue damage  
Methods of treating a subject who has an tissue damage or who is at risk for tissue necrosis are disclosed. Also disclosed are methods of treating a subject who has an inflammatory disorder. The...