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US20070102111 |
Controlled nanotube fabrication and uses
A method and apparatus are provided for the formation of nanotubes and nanotube related structures. Nanotubes, such as carbon nanotubes, can be prepared to exhibit various physical, chemical and...
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US20070099976 |
3-3-DI-SUBSTITUTED-OXINDOLES AS INHIBITORS OF TRANSLATION INITIATION
Compositions and methods for inhibiting translation using 3-(5-tert-Butyl-2-Hydroxy-phenyl)-3-phenyl-1,3-dihydro-indol
-2-one and/or its derivatives are provided. Compositions, methods and kits for...
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US20070098696 |
Immortalized fibroblasts
Aspects of the invention provide an immortalized fibroblast cell line capable of the growth and maintenance of human embryonic stem cells. An immortalized fibroblast cell line derived from an early...
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7211464 |
Doped elongated semiconductors, growing such semiconductors, devices including such semiconductors and fabricating such devices
A bulk-doped semiconductor that is at least one of the following: a single crystal, an elongated and bulk-doped semiconductor that, at any point along its longitudinal axis, has a largest...
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US20070093413 |
Histone deacetylases, and uses related thereto
The present invention concerns the discovery that proteins encoded by a family of genes, termed here HDx-related genes, which are involved in the control of chromatin structure and, thus in...
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US20070093410 |
Selective inhibition of proteasomes of tuberculosis and other bacteria
Compositions and methods for inhibiting bacterial proteasomes are provided. Methods of screening antibacterial compounds, methods of treating bacterial infections and disorders associated with...
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US20070092914 |
Compartmentalised screening by microfluidic control
The invention describes a method for the identification of compounds which bind to a target component of a biochemical system or modulate the activity of the target, comprising the steps of: a)...
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US20070087362 |
Polony fluorescent in situ sequencing beads
Miniaturized, high-density, bead-based arrays are provided. Methods of producing and using clonal beads and producing and using miniaturized, high density, bead-based arrays are also provided.
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7202333 |
DNA encoding IgE Receptor α-subunit or fragment thereof
A cDNA sequence encoding the α-subunit of human mast cell IgE surface receptor or an IgE binding fragment thereof.
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7199132 |
Tropane analogs and methods for inhibition of monoamine transport
New tropane analogs that bind to monoamine transporters are described, particularly, 8-aza, 8carbo and 8-oxo tropanes having 6- or 7-hydroxyl or ketone substituents. The compounds of the present...
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7198747 |
Fabrication of ceramic microstructures
The invention provides ceramic molded solid articles and methods for making these articles on the micron scale. Articles are molded from ceramic precursors, optionally using molds including at...
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US20070065829 |
In vitro differentiation of vascular smooth muscle cells, methods and reagents related thereto
This invention is directed to an in vitro system for rapidly and uniformly inducing immortalized neural crest cells to differentiate to vascular smooth muscle cells. As excessive proliferation of...
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7192739 |
Ligand-dependent protein splicing
Ligand-dependent inteins allow for modulation of a protein's activity in vivo. Upon binding of the ligand to the ligand-dependent intein inserted into the protein of interest, the hybrid protein...
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7192735 |
Phosphopantetheinyl transferases and uses thereof
The invention pertains to isolated phosphopantetheinyl transferases, such as the E. coli acyl carrier protein synthase, which transfer a phosphopantetheinyl group onto a substrate. The enzyme can...
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7192713 |
Stabilized compounds having secondary structure motifs
The present invention provides novel stabilized crosslinked compounds having secondary structure motifs, libraries of these novel compounds, and methods for the synthesis of these compounds...
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7189503 |
Characterization of individual polymer molecules based on monomer-interface interactions
The invention relates to a method for detecting a double-stranded region in a nucleic acid by (1) providing two separate, adjacent pools of a medium and a interface between the two pools, the...
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US20070055459 |
Structure-based approach to design of protein-processivity factor interactions
A method for the structure-based identification and selection of inhibitors of processivity factor binding to protein is disclosed herein. Characterization of the protein/processivity factor...
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US20070052781 |
Microfluidic manipulation of fluids and reactions
The present invention relates generally to microfluidic structures, and more specifically, to microfluidic structures and methods including microreactors for manipulating fluids and reactions. In...
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7186709 |
Dihydropyrancarboxamides and uses thereof
The present invention provides novel dihydropyrancarboxamide compounds of formula (I): and collections of these compounds, and provides methods for the synthesis of these compounds; wherein R1–R6 a...
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US20070048492 |
Doped elongated semiconductors, growing such semiconductors, devices including such semiconductors, and fabricating such devices
A bulk-doped semiconductor that is at least one of the following: a single crystal, an elongated and bulk-doped semiconductor that, at any point along its longitudinal axis, has a largest...
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US20070045667 |
Nanoscopic wired-based devices and arrays
Electrical devices comprised of nanoscopic wires are described, along with methods of their manufacture and use. The nanoscopic wires can be nanotubes, preferably single-walled carbon nanotubes....
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7183417 |
Simple stereocontrolled synthesis of salinosporamide A
A simple and effective stereocontrolled synthesis of salinosporamide A(1) has been developed which follows the pathway outlined in the FIGURE. The process, the first total synthesis of...
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7183059 |
Synthesis of compounds and libraries of compounds
A method of generating a compound having at least one biological activity of a peptide. The method includes identifying a biologically active peptide, providing a first monomer which contains...
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7183054 |
Assay for identifying biological targets of polynucleotide-binding compounds
The present invention provides methods and systems for the identification of a biological target of a chemical compound, such as saframycin A, known to bind a polynucleotide. The invention also...
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7183049 |
***WITHDRAWN PATENT AS PER THE LATEST USPTO WITHDRAWN LIST***
Cell regulatory genes, encoded products, and uses related thereto
This application describes the cloning of p63, a gene at chromosome 3q27-29, that bears homology to the tumor suppressor p53. The p63 gene encodes at least six different isotypes. p63 was detected...
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US20070032052 |
Doped elongated semiconductors, growing such semiconductors, devices including such semiconductors, and fabricating such devices
A bulk-doped semiconductor that is at least one of the following: a single crystal, an elongated and bulk-doped semiconductor that, at any point along its longitudinal axis, has a largest...
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US20070032051 |
Doped elongated semiconductors, growing such semiconductors, devices including such semiconductors, and fabricating such devices
A bulk-doped semiconductor that is at least one of the following: a single crystal, an elongated and bulk-doped semiconductor that, at any point along its longitudinal axis, has a largest...
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US20070032023 |
Doped elongated semiconductors, growing such semiconductors, devices including such semiconductors, and fabricating such devices
A bulk-doped semiconductor that is at least one of the following: a single crystal, an elongated and bulk-doped semiconductor that, at any point along its longitudinal axis, has a largest...
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7172953 |
Methods of forming nanoscopic wire-based devices and arrays
Electrical devices comprised of nanoscopic wires are described, along with methods of their manufacture and use. The nanoscopic wires can be nanotubes, preferably single-walled carbon nanotubes....
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US20070026645 |
Doped elongated semiconductors, growing such semiconductors, devices including such semiconductors, and fabricating such devices
A bulk-doped semiconductor that is at least one of the following: a single crystal, an elongated and bulk-doped semiconductor that, at any point along its longitudinal axis, has a largest...
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US20070021341 |
Treatment of autoimmune conditions with Copolymer 1 and related Copolymers
The present invention is directed to polypeptides containing at least three amino acids randomly joined in a linear array; wherein at least one of the three amino acids is an aromatic amino acid,...
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US20070019306 |
Microlens for projection lithography and method of preparation thereof
Methods and systems for effecting responses on surfaces utilizing microlens arrays including microoptical components embedded or supported by a support element and positioned from the surface at a...
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US20070009918 |
Methods and compositions for regulating T cell subsets by modulating transcription factor activity
Methods for modulating production of a T helper type 2 (Th2)-associated cytokine, in particular interleukin-4, by modulating the activity of a transcription factor, in particular the...
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US20070009432 |
Boat tropanes
Radiopharmaceutical compounds are disclosed. A tropane compound is linked through the N atom at the 8-position to a chelating ligand capable of complexing technetium or rhenium to produce a neutral...
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US20070004005 |
Tendon-inducing compositions
Compositions of proteins with tendon/ligament-like tissue inducing activity are disclosed. The compositions are useful in the treatment of tendinitis and tendon or ligament defects and in related...
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US20070003442 |
Electronic control of fluidic species
Various aspects of the present invention relate to the control and manipulation of fluidic species, for example, in microfluidic systems. In one aspect, the invention relates to systems and methods...
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US20070001125 |
SURFACE PLASMON ENHANCED ILLUMINATION APPARATUS HAVING NON-PERIODIC RESONANCE CONFIGURATIONS
An apparatus configured to generate surface plasmon enhanced radiation comprises a metal film having first and second surfaces, and one or more resonance configurations formed in the metal film. An...
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7154965 |
Soft detection of data symbols in the presence of intersymbol interference and timing error
A method for detecting data symbols corrupted by intersymbol interference and timing error, comprises calculating a first plurality of state probabilities for received symbols using a forward...
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US20060280029 |
Microfluidic mixer
The present invention relates generally to microfluidic systems and, more specifically, to apparatuses and methods associated with mixing in microfluidic systems. In some embodiments, a mixer is...
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7144905 |
Small molecules used to increase cell death
The invention features methods for increasing cell death. The invention also features compounds used to increase cell death. The invention further features methods for identifying compounds that...
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7144732 |
Vertebrate embryonic pattern-inducing proteins and uses related thereto
The present invention concerns the discovery that proteins encoded by a family of vertebrate genes, termed here hedgehog-related genes, comprise morphogenic signals produced by embryonic patterning...
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US20060261905 |
METHODS AND APPARATUS BASED ON COPLANAR STRIPLINES
A standing wave oscillator to generate at least one voltage standing wave, comprising a closed-loop coplanar stripline including two conductors, and at least one amplifier disposed between the two...
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US20060257936 |
Methods, products and treatments for diabetes
The invention involves assays, diagnostics, kits, and assay components for determining levels of K41-glycated CD59 in subjects. Treatments for subjects based upon levels of K41-glycated CD59 also...
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US20060257316 |
Methods for diagnosing and monitoring treatment ADHD by assessing the dopamine transporter level
A method of diagnosing attention deficient-hyperactivity disorder (ADHD) in a human patient by assessing the level of dopamine transporter in at least one region of the patient's central nervous...
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7132231 |
Fluorescence polarization method for determining viral inhibitors
Methods for determining inhibitors of protein interactions are provided. The method involves evaluation of potential inhibitors that can inhibit or prevent protein interactions. The method provides...
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US20060246543 |
Slim compositions and methods of use thereof
This invention is based, at least in part, on the discovery of a novel nuclear protein which contains both PDZ and LIM domains, SLIM (STAT-interacting LIM). SLIM interacts with activated STAT...
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7129554 |
Nanosensors
Electrical devices comprised of nanoscopic wires are described, along with methods of their manufacture and use. The nanoscopic wires can be nanotubes, preferably single-walled carbon nanotubes....
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US20060239909 |
Treatment of protein degradation disorders
The invention relates to methods of treating protein degradation disorders, such cellular proliferative disorders (e.g., cancer) and protein deposition disorders (e.g., neurodegenerative...
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US20060237749 |
Nanoscopic wire-based devices and arrays
Electrical devices comprised of nanoscopic wires are described, along with methods of their manufacture and use. The nanoscopic wires can be nanotubes, preferably single-walled carbon nanotubes....
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US20060231914 |
Silicon-based visible and near-infrared optoelectric devices
In one aspect, the present invention provides a silicon photodetector having a surface layer that is doped with sulfur inclusions with an average concentration in a range of about 0.5 atom percent...
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