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5157123 |
S-(2-thiopyridyl)-L-cysteine, a heterobifunctional crosslinking reagent
Site-specific heterobifunctional crosslinkers of the formula: X--COCH(NH2)--Y--Zwhere X is a carbonyl reactive group, Y is a variable length spacer, and Z is a thiol reactive group, are useful for...
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5153216 |
Method for treating chest pain
The known compound 1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)me
thyl]4H-carbaz ol-4-one, which is available commercially as the dihydrate of its hydrochloride acid addition salt, is...
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5148812 |
Non-invasive dynamic tracking of cardiac vulnerability by analysis of T-wave alternans
A non-invasive method for dynamic tracking of cardiac vulnerability to ventricular fibrillation is disclosed. A heart is monitored to sense an ECG signal. The sensed ECG signal is then amplified...
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5106762 |
Ligand-label conjugates which contain polyoxoanions of sulfur or phosphorus
Ligand-label conjugates which are an oligopeptide of 5 to 100 amino acid residues, bonded to a ligand or receptor, which contain a plurality of chemiluminescent or fluorescent labels and a...
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5091523 |
Mitomycin derivatives having reduced bone marrow toxicity, processes for their preparation, and the uses thereof
The invention relates to certain derivatives of mitomycins A and C and the use thereof to treat bacterial infections and to supress the growth of cancer cells. The invention also relates to...
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5069223 |
Method of evaluating tissue changes resulting from therapeutic hyperthermia
A method of evaluating tissue changes in a mammal occurring as a result of applying a therapeutic hyperthermia treatment to a volume of tissue of the mammal, which entails: a) placing electrodes...
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5057411 |
Type-specific papillomavirus DNA sequences and peptides
The polynucleotide sequence fragment conferring immunologic specificity to papillomavirus (PV) has been located and isolated. From this information, assays for type-specific PV, including DNA...
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5001225 |
Monoclonal antibodies to a pan-malarial antigen
A continuous hybridoma cell line, designated 7H8, which secretes a monoclonal antibody (MAb 7H8) of the IgM class and which binds to a protein present in species of the genus Plasmodium. MAb 7H8...
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4956459 |
Platinum compounds suitable for use as pharmaceuticals
Compounds of the formula: ##STR1## wherein each of R1 and R2 is independently selected from the group consisting of halogen, hydroxy, or mono carboxylic acid or R1 and R2 together is a...
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4952408 |
Liposome-encapsulated vinca alkaloids and their use in combatting tumors
A composition made up of a liposome-encapsulated vinca alkaloid is disclosed. This composition possesses an increased antitumor activity and a substantially lower toxicity as compared to free drug.
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4946954 |
Platinum pharmaceutical agents
Platinum compounds useful in the treatment of cancer are disclosed. Compositions containing these compounds and methods of using the same are also discussed. Compounds having the formula ##STR1##...
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4895936 |
Platinum pharmaceuticals
Platinum compounds useful in the treatment of cancer are disclosed. Compositions containing these compounds and methods of using the same are also discussed. The compound have the formula: ##STR1##...
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4895935 |
Platinum pharmaceuticals
Platinum compounds of the formulae: ##STR1## are disclosed. Compositions containing these compounds and methods of using the same in the treatment of tumors are also discussed.
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4801678 |
Poly(2,6-naphthoquinone) film and the preparation and uses thereof
A rechargeable electrochemical storage cell comprising a housing, in the interior of which is an anode and a cathode spaced from each other and both provided with a core of glassy carbon, graphite...
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4790961 |
Thermally reversible organic solvent gels
Stable, thermally reversible gels of organic solvents and a gelling agent having the formula R1 --(CH2)n --CO2 --R2wherein R1 is an anthracene analogue or substituted anthracene analogue, n is zero...
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4764462 |
Detectably labeled cephalosporin assay for beta-lactamase
This invention provides for a cephalosporin immobilized on a solid phase support comprising a beta-lactamase releasable, detectably labeled substituent at the 3-position thereof.This invention also...
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4720543 |
1a-7-substituted derivatives of mitomycin and uses thereof
This invention discloses 1a- and 7-substituted derivatives of mitosanes containing thiocarbamoyl and glycosyl residues. The compounds possess antibacterial and antitumor activity, with a...
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4716225 |
Radioopaque sugar derivatives and a method of metabolic mapping using the same
A method of metabolically mapping one or more central nervous system components of a mammalian body by computerized axial tomography scanning which entails injecting an effective amount of a 2-, 5-...
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4657851 |
Breast cancer diagnostic blood test
A method for detecting an antigen in a plasma or serum sample, which comprises conditioning the sample, wherein conditioning comprises either diluting the sample by a factor of at least 100 or...
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4656159 |
Galactose-C-6 nitrogen mustard compounds and their uses
Compounds of the formula ##STR1## wherein X is halogen; each R independently represents H, a C1 -C4 alkyl group, a C2 -C4 alkanoyl group, a phosphate group, or a sulfate, sulfonate, or benzoate...
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4634417 |
Process for treatment of tumors and apparatus therefor
A process for removing immunosuppressive substances from the blood serum of cancer patients comprises contacting the serum at a temperature below room temperature and preferably not greater than...
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4493039 |
Apparatus and method for image reproduction of materials using their magnetic and electric properties
Pictorial images of selected volume elements of materials are generated by a contactless, non-destructive, substantially hazard free tomographic technique in which the material is brought within...
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4478816 |
Rare earth/chelating agent complex for digital fluoroscopy
A rare earth/chelating agent complex is employed in digital fluoroscopy. More specifically, a contrast medium is utilized in digital fluoroscopy, the contrast medium consisting of a non-radioactive...
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4474186 |
Computerized electro-oculographic (CEOG) system with feedback control of stimuli
A computerized electro-oculographic (CEOG) system with feedback control of test stimuli comprises an integrated system for automated administration of electro-oculographic tests and visual evoked...
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4459356 |
Radioactive staining of gels to identify proteins
Radioactive staining of gels is employed to identify proteins. A radioactive stain composition is formed by introducing radioactive iron isotope into ferrous bathophenanthroline sulfonate by adding...
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4450478 |
Digital fluorographic method and system
A digital fluorographic method and system calls for digitizing and storing first and second x-ray picture information derived prior to and after, respectively, injection of a contrast medium into...
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4433286 |
Identification of materials using their complex dielectric response
The non-linear conductance and capacitance characteristics of electrically non-homogenous materials over a given frequency range are used to identify and analyze such materials.
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4419348 |
Anthracycline glycoside compositions, their use and preparation
Anthracycline glycoside antibiotics are complexed with cardiolipin and then encapsulated in liposomes to reduce mammalian cardiac tissue uptake of the anthracycline glycoside and to thereby reduce...
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4417967 |
Grooved gel
A grooved gel arrangement comprises a base portion having grooves extending in a longitudinal direction thereof, a gel disposed on the grooved portion and filling in the grooves, and a top portion...
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4409616 |
Digital dental system and method
A digital dental system and method for real time display of a patient's dental image to detect changes with respect to at least one previous dental image of the patient. The system comprises an...
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4370611 |
Identification of materials using their complex dielectric response
The non-linear conductance and capacitance characteristics of electrically non-homogenous materials over a given frequency range are used to identify and analyze such materials.
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4320768 |
Computerized electro-oculographic (CEOG) system
A computerized electro-oculographic (CEOG) system comprises an integrated system for automated administration of electro-oculographic tests and visual evoked response tests to a patient, and...
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4271706 |
Ultrasonic scanner
An ultrasonic pulse is directed into a body and electrical representations of pulse reflections from body interfaces along its path are generated. The ultrasonic signal path is scanned through a...
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4263551 |
Method and apparatus for identifying conductive objects by monitoring the true resistive component of impedance change in a coil system caused by the object
The type of conductor, its property, and if a metal, its type and cross-sectional area can be obtained from measurements made at different frequencies for the amount of unbalance created in a...
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4044261 |
Method and system for improving the definition of a scintillation detector
The definition of a tomographic readout image is highly sharpened and improved by minimizing or eliminating the effects of persisting images in the electronic scintillating circuit resulting from...
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4005311 |
Diagnostic X-ray systems
A shutter arrangement and activator device for a diagnostic X-ray machine of the type which rotates about the patient while scanning with thin beams for analysis by computers for storing and...
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3665761 |
LIQUID VAPORIZATION CALORIMETER
A calorimeter assembly comprising Dewar flask means, a sealed vacuum container positioned in the bottom of the Dewar flask means and a sealed sample holding container positioned in the vacuum...
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3643176 |
SUPERCONDUCTOR ELECTRO-MAGNETIC RADIATION DEVICE
An injection-type junction superconducting radiation device, operated below the transition temperature of the superconductor. The junction is formed from a normal metal, an oxide insulative film...
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3624402 |
ELECTROMAGNETIC BEAM COMMUNICATION UNIT
A modulation cell which has two crystals side-by-side and oppositely oriented are driven by the same electromagnetic frequency modulated signal transmitter to form in the cell two parallel but...
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4336493 |
***WITHDRAWN PATENT AS PER THE LATEST USPTO WITHDRAWN LIST***
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3367788 |
Substantially radiopaque tooth lining composition
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