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6395715 |
Uteroglobin gene therapy for epithelial cell cancer
The present invention provides a novel method for inhibiting the growth of tumor cells of epithelial origin, comprising administration of a functional uteroglobin gene in a gene therapy regime, so...
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6358915 |
Methods for inhibiting metastasis
The invention relates to methods for determining degree of integrin-mediated maintenance of cell invasive capacity of tumors, and to methods and compositions for inhibiting or preventing metastasis...
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6355416 |
Assay for the measurement of DNA synthesis rates
Use of nonradioactive tracer technology used to measure DNA synthesis rates. DNA synthesis is determined by administering one or more stable isotope labelled precursors to one or more of DNA...
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6335321 |
Non-steroidal anti-inflammatory agent therapy for epithelial cell cancer
The invention relates to methods for identifying prostatic intraepithelial neoplasia, methods for determining metastatic potential of tumors, and to methods and compositions for inhibiting or...
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6288039 |
Pharmaceutical compositions methods and kits for treatment and diagnosis of breast cancer
The present invention relates to pharmaceutical compositions, methods and kits that provide for the early diagnosis and treatment of breast cancer. More particularly, the present invention relates...
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6219988 |
Wrapping system for strengthening structural columns or walls
A method of reinforcing a substantially vertical support structure comprising the steps of: wrapping at least one sheet of resin impregnated high strength fiber around the support structure to form...
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6184863 |
Direct pointing apparatus and method therefor
The direct pointing apparatus and method therefor has a light sensing arrangement including a plurality of light receivers positioned around the outer periphery of a computer display and A/D...
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6166379 |
Direct injection high efficiency nebulizer for analytical spectrometry
A simple, relatively low-cost direct injection high efficiency nebulizer (DIHEN) is suitable for argon inductively coupled plasma (Ar ICP) spectrometry. The DIHEN may be operated at solution uptake...
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6145071 |
Multi-layer multi-processor information conveyor with periodic transferring of processors' states for on-the-fly transformation of continuous information flows and operating method therefor
In a multi-processor computing system, a multi-layer architecture is described in which each layer has a plurality of dual ported microprocessors, one port of which receives data for processing and...
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6138456 |
Pressure exchanging ejector and methods of use
A novel pressure-exchange ejector is disclosed whereby a high energy primary fluid compresses a lower energy secondary fluid through direct fluid-fluid momentum exchange. The pressure-exchange...
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6121328 |
Racemic propranolol
Pharmaceutical formulations of mixtures of the D and L configuration of propranolol are disclosed which have antioxidant activity and reduced β blocking activity.
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6100297 |
Intravenous magnesium gluconate for treatment of conditions caused by excessive oxidative stress due to free radical distribution
The intravenous use of magnesium gluconate to substantially block free radical surge in the treatment of ischemia/reperfusion (I/R) injury due to oxidative stress.
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6077525 |
Use of conjugated linoleic acids
The use of conjugated linoleic acid to inhibit cyclooxygenase-catalyzed conversion of arachidonic acid, thromboxane formation and platelet aggregation.
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6054320 |
Kit for indentifying prostatic intraepithelial neoplasia (PIN)
The invention relates to methods for identifying prostatic intraepithelial neoplasia, methods for determining metastatic potential of tumors, and to methods and compositions for inhibiting or...
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5935860 |
Use of uteroglobin expression as a molecular marker for prostatic intraepithelial neoplasia
The invention relates to methods for identifying prostatic intraepithelial neoplasia by determining the uteroglobin concentration in a tissue sample.
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5919934 |
Compounds, compositions, and methods for cancer imaging and therapy
Disclosed are bisaminothiol and amino compounds with appended pharmacophores, complexes of these compounds with 99m Tc(V)0, Re(V)0, In+3, 67 Ga+3, 90 Y+3, 109 Pd+2 or 105 Rh+3, and pharmaceutical...
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5830640 |
Determining invasiveness of prostatic adenocarcinoma
The invention relates to methods for determining metastatic potential of tumors and to methods and compositions for inhibiting or preventing metastasis of cancers. In one aspect, the invention...
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5776985 |
Fluorinated propranolol and related methods
Fluorinated beta blockers, such as propranolol, are presented with amplified antioxidant effects and various levels of beta blocking effects. Mixtures are also presented of fluorinated antioxidant...
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5721211 |
Compositions and methods for treating small cell and nonsmall cell lung cancers
Compositions and methods of use thereof for treating small cell and nonsmall cell lung cancers in mammals are disclosed. The compositions comprise substances that inhibit the lung cancer cell...
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5696092 |
Methods and compositions for inhibiting metastasis of epithelial cell-derived cancers
The present invention relates to methods and compositions that prevent or inhibit metastases of cancers of epithelial cell origin, especially human prostate cancers. A particular aspect of the...
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5647221 |
Pressure exchanging ejector and refrigeration apparatus and method
A novel ejector, an ejector-refrigeration system, and a method of refrigeration are disclosed. The system is particularly well suited for the utilization of energy sources such as waste heat from...
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5593964 |
Method of treating septic shock by preventing actin polymerization
A method of treating septic shock in a mammal by preventing in vivo polymerization of actin in the mammal. An actin antipolymerizer such as thymosin β4 (Tβ4) is administered to the mammal so as t...
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5585352 |
Method of treating septic shock using thymosin-α 1
A method of reducing toxicity of endotoxin in a mammal including the administration of an endotoxin-reducing effective amount of Tα1 to the mammal.
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5585234 |
Treatment of infertile sperm in vitro with thymosin α1 to enhance penetration of mammalian ova
The present invention relates to a method for increasing penetration of mammalian ova by mammalian male sperm by contacting sperm in vitro with a penetration-enhancing amount of a...
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5578570 |
Method of treating septic shock using thymosin β4
A method of treating septic shock in a mammal including the administration of a septic shock-treating effective amount of thymosin β4 (Tβ4) to the mammal. Included is a process directed to o...
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5273963 |
Compositions and methods for treating small cell and nonsmall cell lung cancers
Compositions and methods of use thereof for treating small cell and nonsmall cell lung cancers in mammals are disclosed. The compositions comprise substances that inhibit the lung cancer cell...
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5250031 |
Locking needle cover
A locking protective cover for a needle or cannula of a hypodermic syringe, blood collector or other device includes a retractable cap member connected to the base of the needle by a resilient...
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5132401 |
MB-35 a peptide enhancing the production of growth hormone and prolactin from the anterior pituitary
A peptide of the formula ##STR1## has been isolated from thymosin fraction 5 (TF-5) and synthetically produced. This peptide, which has 100% homology with a region of histone 2A is able to...
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4810781 |
Methods of preparing epitopes of tumor associated antigens
Methods are disclosed for preparing (1) a pure, biologically active, immunogenic tumor-associated antigen by forming a soluble pool of membrane proteins from antigenic tissue and, by separating,...
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4543340 |
Radioimmunoassay of thymosin β4
A radioimmunoassay for the polypeptide thymic hormone thymosin β4 is described. The assay employs a radiolabelled Tyr-C13-thymosin β4 -analogue as probe and a thymosin β4 antibody.
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4541957 |
Process for preparing iodovinyl-estradiol
17α-[(E)-2-Iodovinyl]-estra-1,3,5(10)-triene-3,17β-diol wherein the iodine atom is radioactive can be produced from (E)-[3-acyloxy-17β-hydroxyestra-1,3,5(10)-triene-17α-yl]vi
nyl dih...
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4395404 |
Synthetic thymosin β3 and β4 analogues
Novel peptides representing fragments of thymosin β3 and β4 have been synthesized and are active agents affecting regulation, differentiation and function of thymus dependent lymphocytes and m...
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4339427 |
Radioimmunoassay of thymosinα
An improved radioimmunoassay for the polypeptidic thymic hormone thymosinα1 is described. The assay employs a radiolabelled [Tyr1 ]-thymosinα1 or [Tyr1 ]-desacetylthymosinα1 as probe and an af...
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4264571 |
Radioimmunoassay of thymosin α1
An immunoassay for the polypeptidic thymic hormone thymosin α1 is described. Determination of thymosin α1 levels in biological fluids, particularly serum, provides a useful diagnostic test for i...
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