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5726294 |
Metalorganic chemical vapor deposition method for depositing F-series metal or nitrogen and metal amides for use in MOCVD
A metalorganic chemical vapor deposition (MOCVD) method for depositing an F-series metal onto a semiconductor or other substrate or for incorporating nitrogen as a p-type dopant in Group II-VI...
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5723634 |
Metal alkoxide compounds
A process for preparing N-acyl, N-sulfonyl and N-phosphoryl substituted isoserine esters in which a metal alkoxide is reacted with a β-lactam.
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5721268 |
C7 taxane derivatives and pharmaceutical compositions containing them
Taxane derivatives having alternative C7 substituents.
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5721235 |
Pharmaceutical composition containing bromocryptine and use of same for acquired immunodeficiency states
The following description refers to a pharmaceutical composition containing bromocryptine and the use of same for the treatment of acquired immunodeficiency states.
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5717115 |
Metal alkoxides and ammonium alkoxides
A process for preparing N-acyl, N-sulfonyl and N-phosphoryl substituted isoserine esters in which a metal or an ammonium alkoxide is reacted with a β-lactam.
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5714513 |
C10 taxane derivatives and pharmaceutical compositions
Taxane derivatives having alternative C10 substituents.
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5710287 |
Taxanes having an amino substituted side-chain and pharmaceutical compositions containing them
Taxane derivatives having an amino substituted C13 side chain.
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5700825 |
Radiosensitizing diamines and their pharmaceutical preparations
A compound comprising a diamine containing from 2-4 electron-affinic radiosensitizing functional groups or a salt thereof is provided. In a preferred embodiment the compound has the formula...
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5654447 |
Process for the preparation of 10-desacetoxybaccatin III
A process for abstracting a C10 hydroxy, acyloxy or sulfonyloxy substituent from a taxane in which the C10 hydroxy, acyloxy or sulfonyloxy substituted taxane is reacted with samarium diiodide.
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5649066 |
Method and apparatus for refinement of learning in expert networks
A method for constructing an expert network apparatus from a specific rule-based expert system, having a certainty factor, through the use of a first-order network structure comprising regular node...
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5637732 |
Tricyclic and tetracyclic taxanes
The synthesis of taxol and other tricyclic and tetracyclic taxanes.
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5627140 |
Enhanced flux pinning in superconductors by embedding carbon nanotubes with BSCCO materials
Enhanced flux pinning in superconductors is achieved by embedding carbon nanotubes into a superconducting matrix. The carbon nanotubes simulate the structure, size and shape of heavy ion induced...
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5618952 |
Synthetic process for the preparation of tricyclic and tetracyclic taxanes
Process for the synthesis of taxol and other tricyclic and tetracyclic taxanes.
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5607835 |
Species-specific DNA probes for vibrio cholerae and methods
The present invention relates to species-specific DNA probes specific for Vibrio vulnificus and Vibrio cholerae. The DNA probes of the present invention specifically detects Vibrio vulnificus or...
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5587489 |
Taxane and baccatin III analogs bearing new C2 and C4 functional groups
Process for the preparation of a derivative or analog of baccatin III or 10-desacetyl baccatin III having a C2 substituent other than benzoate and/or a C4 substituent other than acetate in which...
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5583205 |
Metalorganic chemical vapor deposition method for depositing f-series metal or nitrogen and metal amides for use in mocvd
A metalorganic chemical vapor deposition (MOCVD) method for depositing an F-series metal onto a semiconductor or other substrate or for incorporating nitrogen as a p-type dopant in Group II-VI...
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5581182 |
Method and apparatus for broadband decoupling in nuclear magnetic resonance with chirp pulses
Methods and apparatus for broadband decoupling in nuclear magnetic resonance with chirp and other RF pulses are disclosed. Such methods may include the step of positioning the sample in a static...
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5574156 |
β-lactams used in preparing taxol
A β-lactam of the formula: ##STR1## wherein R1 is aryl, substituted aryl, alkyl, alkenyl, or alkynyl; R2 is hydrogen, alkyl, acyl, acetal, ethoxyethyl, or other hydroxyl protecting group; and R3 ...
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5552551 |
Proton-transfer, low self-absorbing chromophores for use in scintillators
Proton-transfer, low self-absorbing chromophores of the formula: ##STR1## wherein R2 and R3 are independently hydrogen, alkyl, aryl, cyano, nitro, halo or an ether group, R4 is O or N--H, and R5 is...
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5539103 |
β-lactams as taxol intermediates N-acylated
β-lactam compounds which are reacted with a metal alkoxide for preparing N-acyl, N-sulfonyl and phosphoryl substituted isoserine esters.
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5532363 |
Heteroaryl substituted oxazinone compounds for the preparation of taxol
Process for the preparation of a taxol intermediate comprising contacting an alcohol with an oxazinone having the formula: ##STR1## wherein R1 is aryl, heteroaryl, alkyl, alkenyl, alkynyl or OR7...
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5524176 |
Fuzzy expert system learning network
In the present invention, prior art techniques are extended to allow application of the backpropagation learning technique to artificial neural networks derived from fuzzy expert system rule-bases....
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5489601 |
Taxanes having a pyridyl substituted side-chain and pharmaceutical compositions containing them
Taxane derivatives having a 3' pyridyl substituted C13 side chain.
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5470834 |
Sulfoximine and suldodiimine matrix metalloproteinase inhibitors
Novel sulfoximine and sulfodiimine matrix metalloproteinase inhibitors of the formula, ##STR1## wherein: R1 is selected from the group consisting of lower-alkyl, hydroxy lower-alkyl, amino...
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5466930 |
Solid scintillators for detecting radioactive ions in solution
A scintillator for absorbing and concentrating radioactive ions within a solution, the scintillator including a solid scintillator and an ionic layer on a surface of and in contact with the solid...
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5466834 |
Preparation of substituted isoserine esters using metal alkoxides and .beta .
A process for preparing N-acyl, N-sulfonyl and N-phosphoryl substituted isoserine esters in which a metal alkoxide is reacted with a β-lactam.
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5464813 |
Method of producing superconductor which exhibits critical current density bifurcation
A process for the production of a YBa2 Cu3 O7-x or YBa2 Cu3 O7-x -AgO superconductor includes: providing the appropriate powder or mix of powders, pressing the powder to form the desired specimen,...
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5455262 |
Mercaptosulfide metalloproteinase inhibitors
Novel mercaptosulfide matrix metalloproteinase inhibitors of the Formula I, ##STR1## wherein: n is 0 or 1; R1 is selected from the group consisting of hydrogen, lower alkyl, amino lower alkyl,...
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5430160 |
Preparation of substituted isoserine esters using β-lactams and metal or ammonium alkoxides
A process for preparing N-acyl, N-sulfonyl and N-phosphoryl substituted isoserine esters in which a metal or an ammonium alkoxide is reacted with a β-lactam.
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5426025 |
Species-specific DNA probes for vibrio vulnificus methods and kits
The present invention relates to species-specific DNA probes specific for Vibrio vulnificus and Vibrio cholerae. The DNA probes of the present invention specifically detects Vibrio vulnificus or...
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5405972 |
Synthetic process for the preparation of taxol and other tricyclic and tetracyclic taxanes
Process for the synthesis of taxol and other tricyclic and tetracyclic taxanes.
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5399726 |
Process for the preparation of baccatin III analogs bearing new C2 and C4 functional groups
Process for the preparation of a derivative or analog of baccatin III or 10-desacetyl baccatin III having a C2 substituent other than benzoate and/or a C4 substituent other than acetate in which...
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5384399 |
Oxazinone compounds for the preparation of taxol
Process for the preparation of a taxol intermediate comprising contacting an alcohol with an oxazinone having the formula: ##STR1## wherein R1 is aryl, heteroaryl, alkyl, alkenyl, alkynyl or OR7...
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5350866 |
10-desacetoxytaxol derivatives
The present invention relates to 10-desacetoxytaxol and derivatives thereof, which are useful as antitumor agents. These compounds have the formula ##STR1## wherein R2 is hydrogen, hydroxy or a...
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5338872 |
Process for the preparation of 10-desacetoxybaccatin III and 10-desacetoxytaxol and derivatives thereof
A process for the preparation of a 10-desacetoxy and 10-desoxy tetracyclic taxane in which a tetracyclic taxane having a C10 hydroxy or acetoxy substituent is reacted with samarium diiodide.
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5336785 |
Method for preparation of taxol
A β-lactam of the formula: ##STR1## wherein R1 is aryl, substituted aryl, alkyl, alkenyl, or alkynyl; R2 is hydrogen, alkyl, acyl, acetal, ethoxyethyl, or other hydroxyl protecting group; and R3 ...
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5286710 |
Superconductive alloys having bifurcated critical current density and method of preparation
A device having superconductive and resistive states including an element comprising a high temperature superconductive material having a first (high) state with a first (high) critical current...
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5284864 |
Butenyl substituted taxanes and pharmaceutical compositions containing them
Taxane derivatives of the formula ##STR1## wherein R1 is butenyl, R3 is phenyl, T1 is hydrogen, hydroxyl protecting group, or --COT2, T2 is H, C1 -C6 alkyl, C2 -C6 alkenyl, C2 -C6 alkynyl or...
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5283253 |
Furyl or thienyl carbonyl substituted taxanes and pharmaceutical compositions containing them
Taxane derivatives of the formula ##STR1## wherein R1 is phenyl or p-nitrophenyl, R3 is furyl or thienyl, T1 is hydrogen, hydroxyl protecting group, or --COT2, T2 is H, C1 -C6 alkyl, C2 -C6...
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5274124 |
Metal alkoxides
A metal alkoxide having the following formula: ##STR1## wherein T1 is hydrogen or a hydroxy protecting group, Z is --OT2, or --OCOCH3, T2 is hydrogen or a hydroxy protecting group, and M is...
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5258478 |
Low self-absorbing, intrinsically scintillating polymers
Polymers containing covalently-bonded, low self-absorbing, scintillating chromophores, polymerizable chromophores of the formula: ##STR1## wherein R1 is vinyl, α-methyl vinyl, vinyl phenyl, or ...
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5254703 |
Semi-synthesis of taxane derivatives using metal alkoxides and oxazinones
A process for preparing taxane derivatives taxol by providing a metal alkoxide having the bi, tri-, or tetracyclic taxane nucleus, reacting the metal alkoxide with an oxazinone to form an...
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5250683 |
Certain substituted taxanes and pharmaceutical compositions containing them
A taxane derivative of the formula ##STR1## wherein R1 and R3 are independently selected from the group comprising phenyl, naphthalene, C6 H5 CHCH--, and ##STR2## provided, however, R1 and R3 are...
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5243045 |
Certain alkoxy substituted taxanes and pharmaceutical compositions containing them
A taxane derivative of the formula ##STR1## wherein R1 is phenyl or substituted phenyl, R3 is CH3 O--, or CH3 CH2 O--, Z is --OT1, T1 is hydrogen, hydroxyl protecting group, or --COT2. T2 is H, C1...
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5229526 |
Metal alkoxides
A metal alkoxide having the following formula: ##STR1## wherein T1 is hydrogen or a hydroxy protecting group, Z is --OT2, or --OCOCH3, T2 is hydrogen or a hydroxy protecting group, and M is...
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5227400 |
Furyl and thienyl substituted taxanes and pharmaceutical compositions containing them
A taxane derivative of the formula ##STR1## wherein ##STR2## Z is --OT1, T1 is hydrogen, hydroxyl protecting group, or --COT2, T2 is H, C1 -C6 alkyl, C1 -C6 alkenyl, C1 -C6 alkynyl or monocylic...
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5187147 |
Method for producing freestanding high Tc superconducting thin films
A process for producing a freestanding high Tc superconducting thin film is disclosed, which comprises providing a carbon substrate, depositing a high Tc superconducting thin film on the substrate...
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5181233 |
Specimen holder
A specimen holder including a housing having a specimen chamber in it. A window defining a wall of the chamber allows transmission of at least a portion of the x-radiation from X-ray diffraction...
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5175315 |
Method for preparation of taxol using β-lactam
A β-lactam of the formula: ##STR1## wherein R1 is aryl, substituted aryl, alkyl, alkenyl, or alkynyl; R2 is hydrogen, alkyl, acyl, acetal, ethoxyethyl, or other hydroxyl protecting group; and R3 ...
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5136060 |
Method for preparation of taxol using an oxazinone
Process for the preparation of a taxol intermediate comprising contacting an alcohol with an oxazinone having the formula: ##STR1## wherein R1 is aryl, heteroaryl, alkyl, alkenyl, alkynyl or OR7...
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