Patents and Patent Applications from Emory University


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US20170118634 Methods and Systems for Determining Protected Location Information Based on Temporal Correlations  
The systems and methods can provide location privacy protection by incorporating temporal correlations of a user's locations. The method may include obtaining a first location of a user of a...
US20170114400 Polynucleotide Based Movement, Kits and Methods Related Thereto  
This disclosure relates DNA based movement of objects. In certain embodiments, particles, pairs of particles, or a rods are conjugated with single stranded DNA that hybridizes to a single stranded...
9629543 Internet-based cognitive diagnostics using visual paired comparison task  
Disclosed are methods for diagnosing declarative memory loss using mouse tracking to follow the visual gaze of a subject taking a visual paired comparison test. Also disclosed are methods for...
US20170107489 Therapeutic Use of CD31 Expressing Cells  
The present invention features compositions and methods related to the isolation, culture and therapeutic use of CD31-expressing cells.
US20170106359 WATER OXIDATION CATALYSTS AND METHODS OF USE THEREOF  
Homogeneous water oxidation catalysts (WOCs) for the oxidation of water to produce hydrogen ions and oxygen, and methods of making and using thereof are described herein. In a preferred...
US20170100477 Methods of Immunizing a Subject and Compositions Related Thereto  
This disclosure relates to methods of immunization comprising administering an effective amount of an immunogenic composition comprising an antigen or vaccine and an adjuvant disclosed herein to a...
US20170100283 Tissue Support Structure  
An apparatus includes a component having a shape memory material. The shape memory material has a first shape including a substantially elongate segment. The shape memory material has a second...
9618522 Diagnostic testing in dementia and methods related thereto  
This disclosure relates to diagnostic testing for subjects with or at risk of dementia and methods related thereto. In certain embodiments, the disclosure relates to methods of diagnosing a...
9616070 Use of GABAA receptor antagonists for the treatment of excessive sleepiness and disorders associated with excessive sleepiness  
GABAA receptor mediated hypersomnia can be treated by administering a GABAA receptor antagonist (e.g., flumazenil; clarithromycin; picrotoxin; bicuculline; cicutoxin; and oenanthotoxin). In some...
9605083 JAML specific binding agents, antibodies, and uses related thereto  
Disclosed are specific binding agents such as antibodies and chimera that bind to JAM-like protein. Also disclosed are heavy chain fragments, light chain fragments, and CDRs of the antibodies, as...
US20170082623 Methods of Diagnosing and Treating Tuberculosis  
This disclosure relates to methods of treating and diagnosing a tuberculosis infection as pulmonary active or latent based on biomarkers expressed on pools of CD4+ cells. In certain embodiments,...
US20170081385 Variable Lymphocyte Receptors (VLR) Modifications and Compositions and Uses Related Thereto  
This disclosure relates to variable lymphocyte receptors (VLRs) modifications such as humanized sequences and polypeptides comprising such sequences that specifically bind a target molecule and...
US20170081314 Prostaglandin Receptor EP2 Antagonists, Derivatives, Compositions, and Uses Related Thereto  
The disclosure relates to Prostaglandin receptor EP2 antagonists, derivatives, compositions, and methods related thereto. In certain embodiments, the disclosure relates to methods of treating or...
US20170079971 CHEMOKINE CXCR4 RECEPTOR MODULATORS AND USES RELATED THERETO  
The disclosure relates to chemokine CXCR4 receptor modulators and uses related thereto. In certain embodiments, the disclosure relates to pharmaceutical compositions comprising compounds disclosed...
US20170079950 Methods of Managing Graft Versus Host Disease (GvHD) Using Indole Carboxyaldehydes or Derivatives Thereof  
In certain embodiments, this disclosure relates to methods of treating or preventing HvGD comprising administering an effective amount of indole-2-carboxyaldehyde, indole-3-carboxyaldehyde, or...
US20170079864 Surgical Support Devices and Systems  
These systems and devices can be placed on top of any commercially available standard operating table and therefore can provide a portable and inexpensive alternative to commercially available...
9600881 Methods, systems and computer readable storage media storing instructions for imaging and determining information associated with regions of the brain  
Methods, systems and computer-readable storage mediums relate to imaging techniques of a region, for example, the brain, with magnetization transfer contrast (MTC°) effects with less specific...
9598491 Methods for the treatment of infections and tumors  
PD-1 antagonists are disclosed that can be used to reduce the expression or activity of PD-1 in a subject. An immune response specific to an infectious agent or to tumor cells can be enhanced...
US20170076052 METHODS AND SYSTEMS FOR DYNAMIC MANAGEMENT OF A HEALTH CONDITION  
Methods and systems relate to dynamic management of a health condition based on the changing needs and status of individual patient(s) and/or provider(s). The method may include processing...
US20170073387 Compositions of GM-CSF and Interleukin Fusions for Immune Modulation and Uses Related Thereto  
This disclosure relates to recombinant proteins comprising a GM-CSF sequence and an interleukin sequence and nucleic acids related thereto. In certain embodiments, the disclosure relates to...
US20170071896 BH4 Antagonists and Methods Related Thereto  
The disclosure relates to BH4 inhibitors and therapeutic uses relates thereto. In certain embodiments, the disclosure relates to methods of treating or preventing cancer, such as lung cancer,...
9593125 Heterocyclic flavone derivatives, compositions, and methods related thereto  
In certain embodiments, the disclosure relates to heterocyclic flavone derivatives, such as those described by formula provided herein, pharmaceutical compositions, and methods related thereto. In...
9592226 Solenopsin and derivatives, therapeutic compositions; and methods related thereto  
This disclosure relates to solenopsin derivatives, pharmaceutical compositions, and therapeutic uses related thereto. In certain embodiments, the disclosure relates to compounds of the following...
US20170065615 Steroid Analogues for Neuroprotection  
Provided are steroid analogues functionalized with polar substituents at the C3 and/or C20 positions of the steroid ring system that exhibit improved water solubility. Also provided are...
9585915 Polypeptide hydrogels and uses related thereto  
This disclosure relates to self-assembling peptides that form hydrogels comprising peptide sequences for the activation of signaling pathways. In certain embodiments, the disclosure relates to...
US20170051284 Manipulating MicroRNA for the Management of Neurological Diseases or Conditions and Compositions Related Thereto  
This disclosure relates to manipulating microRNA for the management of neurological disorders and compositions related thereto. In certain embodiments, the disclosure contemplates inhibition of...
US20170049909 COMPOSITIONS FOR THE INACTIVATION OF VIRUS REPLICATION AND METHODS OF MAKING AND USING THE SAME  
Provided herein are recombinant constructs, vectors and expression cassettes including a first promoter which is suitably a tRNA promoter operably connected to a first polynucleotide encoding a...
US20170049815 Selective Chemotherapy Treatments and Diagnostic Methods Related Thereto  
This disclosure relates to methods of identifying subjects that have an increased likelihood of responding to a combination of a poly (ADP) ribose polymerase enzyme inhibitor and a platinum based...
US20170049468 Systems and Methods for Tissue Treatment  
Systems and methods are configured to treat a tissue by automatically linearly oscillating an instrument into a target site. A system may include a body having a length and configured to receive a...
9572864 Compositions and uses of lectins  
The disclosure relates to uses of a purified or isolated lectin to kill bacteria, viruses, and other pathogens. In certain embodiments, the disclosure relates to method of treating or preventing...
9572561 Sternal retractor  
Devices and methods for sternal retraction that reduces bleeding from the cut edges of a sternum and reduces fracturing of the sternum during retraction. The devices and methods involve the use of...
US20170042905 Prostaglandin Receptor EP2 Antagonists, Derivatives, Compositions, and Uses Related Thereto  
The disclosure relates to Prostaglandin receptor EP2 antagonists, derivatives, compositions, and methods related thereto. In certain embodiments, the disclosure relates to methods of treating or...
US20170042572 SYSTEMS FOR IMPLANTING AND USING A CONDUIT WITHIN A TISSUE WALL  
Various embodiments of the present invention provide a conduit system including an outer lumen, an inner lumen, and an attaching device. In other embodiments, a multiple access port device adapted...
9567291 N-(4-(bis(4-(dimethylamino)phenyl)methylene)-8-(dimethylamino)  
This disclosure relates to N-(4-(bis(4-(dimethylamino)phenyl)methylene)-8 -(dimethylamino)naphthalen-1(4H)-ylidene)-N-methylmethanamin ium, derivatives, and uses related thereto. In certain...
US20170037078 2' -DISUBSTITUTED NUCLEOSIDE ANALOGS FOR TREATMENT OF THE FLAVIVIRIDAE FAMILY OF VIRUSES AND CANCER  
The present invention is directed to compounds, compositions and methods for treating or preventing Flaviviridae family of viruses (including HCV, Yellow fever, Dengue, Chikungunya and West Nile...
US20170035771 Compounds and Compositions for Ossification and Methods Related Thereto  
The disclosure relates to compounds and compositions for forming bone and methods related thereto. In one embodiment, the disclosure relates to a composition comprising a compound disclosed...
US20170029407 POTENT AND SELECTIVE INHIBITORS OF HEPATITIS C VIRUS  
The present invention is directed to compounds, compositions and methods for treating or preventing hepatitis C virus (HCV) infection in human subjects or other animal hosts. The compounds are as...
9545403 Chemokine CXCR4 receptor modulators and uses related thereto  
The disclosure relates to chemokine CXCR4 receptor modulators and uses related thereto. In certain embodiments, the disclosure relates to pharmaceutical compositions comprising compounds disclosed...
US20170008947 Expression of Chimeric Polypeptide with Variable Lymphocyte Receptors on Immune Cells and Uses for Treating Cancer  
This disclosure relates to recombinant cellular expression of chimeric proteins with peptide sequences derived from lymphocyte receptors and uses for treating cancer. In certain embodiments, the...
US20170007652 Botanical Extracts and Compounds from Schinus Plants and Methods of Use  
This disclosure relates to extracts from the Anacardiaceae (cashew plant family) and compositions comprising compounds contained therein. In certain embodiments, the extracts are derived from the...
9539082 Tissue support structure  
An apparatus includes a component having a shape memory material. The shape memory material has a first shape including a substantially elongate segment. The shape memory material has a second...
US20170002326 Purification of Cell Mixtures Using Molecular Beacons Targeting Cell Specific RNA  
This disclosure is in the area of research and therapeutics. In certain embodiments, it provides methods to assist in the purification of cell mixtures, e.g., cardiomyocytes, using molecular...
US20170000841 TREATMENT OF KLEBSIELLA PNEUMONIAE WITH LIPOSOMALLY FORMULATED GLUTATHIONE  
The composition of the invention, liposomal glutathione, has been recently shown to have utility for having an antibiotic like effect on Klebsiella pneumonia cultures in vitro, and in vivo as...
US20170000818 NYLON-3 POLYMERS ACTIVE AGAINST CLOSTRIDIUM DIFFICILE  
A method and corresponding composition to inhibit outgrowth of C. difficile spores and/or to inhibit growth of C. difficile vegetative cells in a mammal in which an amount of a nylon-3 polymer or...
US20170000801 TRIARYLMETHANE ANALOGS AND THEIR USE IN TREATING CANCERS  
Compounds, pharmaceutical compositions including the compounds, and methods of preparation and use thereof are disclosed. The compounds are triphenyl methane analogs. The compounds and...
US20170000508 Devices and Methods for Stabilizing Tissue  
The devices and methods relate to devices for stabilizing and/or positioning tissue (e.g., heart) within a surgical area. The device may include an articulating arm and a tissue stabilizing...
US20160375074 Botanical Extracts and Compounds from Castanea Plants and Methods of Use  
This disclosure relates to extracts from chestnut plants and compositions comprising compounds contained therein. In certain embodiments, the extracts are derived from the leaves of a Castanea...
9527881 Steroid analogues for neuroprotection  
Provided are steroid analogues functionalized with polar substituents at the C3 and/or C20 positions of the steroid ring system that exhibit improved water solubility. Also provided are...
US20160369344 Detecting MicroRNA and Iso-MicroRNA to Evaluate Vascular and Cardiac Health  
This disclosure relates to diagnosing or evaluating the state of vascular or cardiac health of a subject by detecting alterations in the microRNA and/or iso-microRNA profile contained in a sample...
US20160368897 Pyrazoline Dihydroquinolones, Pharmaceutical Compositions, and Uses  
This disclosure relates to pyrazoline dihydroquinolone derivates, pharmaceutical compositions, and uses. In certain embodiments, the compounds are selective NMDA receptor inhibitors and are useful...