Patents and Patent Applications from Eastern Virginia Medical School


Matches 1 - 50 out of 69 1 2 >
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US20120016030 METHOXYPOLYETHYLENE GLYCOL THIOESTER CHELATE AND USES THEREOF  
The present invention is directed generally to protecting cells, tissues and organs against the damaging effects of ionizing or other damaging agents associated with radiation or chemotherapy, or...
8083678 System, method and medium for acquiring and generating standardized operator independent ultrasound images of fetal, neonatal and adult organs  
A system, method and medium for standardizing a manner of acquisition and display of ultrasound images. In one embodiment of the invention, a volumetric image of an organ is acquired in a...
US20110236979 Apparatus for Generating Electrical Pulses and Methods of Using Same  
A method and apparatus are provided for delivering an agent into a cell through the application of nanosecond pulse electric fields (“nsPEF's”). The method includes circuitry for delivery of an age...
8008347 Methoxypolyethylene glycol thioester chelate and uses thereof  
The present invention is directed generally to protecting cells, tissues and organs against the damaging effects of ionizing or other damaging agents associated with radiation or chemotherapy, or...
US20110136166 Imaging Mass Spectrometry for Improved Prostrate Cancer Diagnostics  
The invention provides biomarkers that can discriminate between prostate cancer and normal tissue as well as identification of associated metastatic disease. One biomarker was identified as a...
US20110092973 NANOSECOND PULSED ELECTRIC FIELDS CAUSE MELANOMAS TO SELF-DESTRUCT  
Methods for a new, drug-free therapy for treating solid skin tumors through the application of nanosecond pulsed electric fields (“nsPEFs”) are provided. In one embodiment of the invention, the cel...
US20110082375 TRANSVAGINAL ULTRASOUND PROBE SPECULUM  
A transvaginal ultrasound probe speculum is designed for use with a generally cylindrical elongated ultrasound probe. The speculum has an elongated blade having a proximal end and a distal end, and...
US20110079226 CERVICAL OCCLUDER  
A device for occluding a cervix has an elongated conduit sized and shaped to extend from a proximal end outside the vagina to a distal end near the cervix. A loop sized to fit around an exocervix...
US20110045590 CALCIUM-INFLUX INHIBITORY FACTOR AND METHOD OF ISOLATION THEREOF  
A purified factor isolated from human milk is provided. The factor is capable of inhibiting calcium-influx activity in polymorphonuclear leukocytes. A method for purification of the factor is also...
US20110039798 SUBSTITUTED NUCLEOSIDE DERIVATIVES WITH ANTIVIRAL AND ANTIMICROBIAL PROPERTIES  
The present invention relates to fatty acid and fatty alcohol substituted nucleoside derivatives and nucleoside and nucleoside derivatives substituted on multivalent scaffolds (e.g., polymers,...
US20100298645 MAGNARETRACTOR SYSTEM AND METHOD  
A system and method for performing surgical procedures within a body cavity, e.g. abdomen, uses a magnetized device is utilized to allow a surgeon to control intra-abdominal organs and objects. The...
7811772 Apolipoprotein A-II isoform as a biomarker for prostate cancer  
The present invention provides a protein-based biomarker, ApoA-II isoform, that is useful in determining prostate cancer status in a patient. In particular, the biomarker of this invention is...
7704983 Antiprogestin method for reducing side effects associated with low dosage HRT and oral contraception  
Menses regulation and, when desired, contraception is achieved at low doses of estrogen and progestin, which otherwise would create episodes of breakthrough bleeding and/or withdrawal amenorrhea,...
US20100055106 METHODS FOR REGULATING COMPLEMENT CASCADE PROTEINS USING ASTROVIRUS COAT PROTEIN AND DERIVATIVES THEREOF  
The present invention provides a method for modulating the complement cascade by depleting the plasma of the functional activity of complement proteins and thereby reducing or eliminating...
US20090306205 METHOXYPOLYETHYLENE GLYCOL THIOESTER CHELATE AND USES THEREOF  
The present invention is directed generally to protecting cells, tissues and organs against the damaging effects of ionizing or other damaging agents associated with radiation or chemotherapy, or...
US20090305212 System, method and medium for simulating normal and abnormal medical conditions  
The present invention provides a system, method and medium for simulating medical conditions to facilitate medical training, that utilizes a roaming device configured to be mobile; a positioning...
US20090275924 Systems and Methods for Monitoring and Controlling Internal Pressure of an Eye or Body Part  
Systems and methods for automatically monitoring and controlling pressure in a body part are disclosed. The systems include an implantable tube with one open end of the tube implanted in the body...
US20090220574 SURAMIN AND DERIVATIVES THEREOF AS TOPICAL MICROBICIDE AND CONTRACEPTIVE  
The present invention is directed to methods of inhibiting STDs by topically administering suramin or a derivative thereof to actual or potential sites of infection, and methods of preventing...
US20090215085 Proteomic Fingerprinting of Human IVF-Derived Embryos: Identification of Biomarkers of Developmental Potential  
The present invention discloses biomarkers and biomarker combinations that have prognostic value as predictors of the developmental potential of individual IVF-derived human embryos. In particular,...
US20090204334 LUNG CANCER BIOMARKERS  
Disclosed are protein biomarkers and their use in diagnosing lung cancer or to make a negative diagnosis in patients. Also disclosed are kits for the diagnosis of lung cancer that detect the...
7565201 Activation of calcium-mediated cell functions in cells and tissues, including aggregation of human platelets. by nanosecond pulsed electric fields  
Methods for inducing calcium mobilization in cells through the application of nanosecond pulsed electric fields (“nsPEFs”) are provided. The invention also provides a method of increasing int...
7538099 Antiprogestin method and kit for reducing side effects associated with low dosage HRT, oral contraception and regulating menses  
Menses regulation and, when desired, contraception is achieved at low doses of estrogen and progestin, which otherwise would create episodes of breakthrough bleeding and/or withdrawal amenorrhea,...
7476693 Suramin and derivatives thereof as topical microbicide and contraceptive  
The present invention is directed to methods of inhibiting STDs by topically administering suramin or a derivative thereof to actual or potential sites of infection, and methods of preventing...
US20090011998 CALCIUM-INFLUX INHIBITORY FACTOR AND METHOD OF ISOLATION THEREOF  
A purified factor isolated from human milk is provided. The factor is capable of inhibiting calcium-influx activity in polymorphonuclear leukocytes. A method for purification of the factor is also...
US20080248500 Apolipoprotein A-II Isoform As A Biomarker For Prostate Cancer  
The present invention provides a protein-based biomarker, ApoA-II isoform, that is useful in determining prostate cancer status in a patient. In particular, the biomarker of this invention is...
7388028 Methoxypolyethylene glycol thioester chelate and uses thereof  
The present invention is directed generally to protecting cells, tissues and organs against the damaging effects of ionizing or other damaging agents associated with radiation or chemotherapy, or...
US20080137877 Subject actuated system and method for simulating normal and abnormal medical conditions  
The present invention provides a system and method for simulating medical conditions to facilitate medical training, that utilizes a stethoscope comprising an earpiece and a headpiece and...
US20080051393 Novel cannabinoids and methods of use  
Water- and lipid-soluble cannabinoid compounds that are agonists for CB1 and CB2 receptors are provided. The cannabinoid compounds are useful for the treatment of retinal neurodegenerative...
RE40119 Adjunctive therapy  
A growth such as a tumor, hypertrophied tissue or cyst is biopsied or more completely excised subsequent to the administration of an effective amount of a gonadotropin releasing hormone analog or...
US20080039524 Methoxypolyethylene glycol thioester chelate and uses thereof  
The present invention is directed generally to protecting cells, tissues and organs against the damaging effects of ionizing or other damaging agents associated with radiation or chemotherapy, or...
7256185 Control of selective estrogen receptor modulators  
The treatment of an estrogen sensitive condition by the administration of a selective estrogen receptor modulator is improved by additionally administering a progestationally active compound to the...
US20070087392 Method for diagnosing head and neck squamous cell carcinoma  
Disclosed are protein biomarkers and their use in diagnosing head and neck squamous cell carcinoma (HNSCC) or to make a negative diagnosis in patients. Also disclosed are kits for the diagnosis of...
US20070015117 System and method for automatic driver evaluation  
Embodiments of the present invention provide a system and method for automatic driver evaluation of a person's driving capabilities and render an outcome of pass or fail without the need for a...
US20060270625 Nutraceuticals for the treatment of neuropathy  
The invention describes a novel combination of neutraceuticals. The invention also provides novel kits comprising a novel combination of neutraceuticals. The invention also provides methods for...
US20060269531 Apparatus for generating electrical pulses and methods of using the same  
A method and apparatus are provided for delivering an agent into a cell through the application of nanosecond pulse electric fields (“nsPEF's”). The method includes circuitry for delivery of an age...
RE39351 High level of expression of INGAP in bacterial and eukaryotic cells  
Removal of the nucleotide sequence encoding the signal peptide from the INGAP coding sequence allows cultured cells to express substantial amounts of INGAP activity. Previous attempts have provided...
RE39299 INGAP protein involved in pancreatic islet neogenesis  
Cellophane wrapping (CW) of hamster pancreas induces proliferation of duct epithelial cells followed by endocrine cell differentiation and islet neogenesis. Using the mRNA differential display...
US20060204958 Methods for diagnosing htlv-i-mediated diseases  
Protein biomarkers that may advantageously be utilized in aiding in, or making, a diagnosis of HTLV-I-associated myelopathy (HAM), adult T-cell leukemia (ATL) or a negative diagnosis are described....
7037663 Human zona pellucida protein 3 and uses thereof  
The present invention provides a method to determine sperm activity comprising the steps of: (a) contacting an appropriate concentration of human zona pellucida protein 3 with an appropriate amount...
US20060088894 Prostate cancer biomarkers  
Protein biomarkers that may advantageously be utilized in diagnosing prostate cancer, benign prostate hyperplasia or to make a negative diagnosis are described. Accordingly, in one aspect of the...
US20060088830 Protein biomarkers that distinguish prostate cancer from non-malignant cells  
This invention provides organic biomolecule markers (e.g., proteins) useful for differentiating prostate cancer, prostate intraepithelial neoplasia or benign prostate hyperplasia, from a negative...
RE39062 INGAP protein involved in pancreatic islet neogenesis  
Cellophane wrapping (CW) of hamster pancreas induces proliferation of duct epithelial cells followed by endocrine cell differentiation and islet neogenesis. Using the mRNA differential display...
7019114 Recombinant, biologically active human zona pellucida protein 3 (HZP3) to test male fertility  
The invention relates to methods for producing recombinant human zona pellucida protein (“rhZP3”) and glycosylated peptide having biological activity of binding to human spermatozoa. A human ova...
US20050251036 System, method and medium for acquiring and generating standardized operator independent ultrasound images of fetal, neonatal and adult organs  
A system, method and medium for standardizing a manner of acquisition and display of ultrasound images. In one embodiment of the invention, a volumetric image of an organ is acquired in a...
US20050214945 Htlv-I tax induced killing of p53 null cancer cells  
This invention is based on the finding that expression of an exogenous nucleic acid encoding a polypeptide having human T-cell leukemia virus type I (HTLV-1) Tax activity in p53 null cells results...
US20050004465 System, method and medium for generating operator independent ultrasound images of fetal, neonatal and adult organs  
A system, method and medium, for use in a medical-imaging environment, that acquires ultrasound image data for at least a portion of a body organ, utilizes data defining a reference plane for the...
US20030148362 Diagnostic microarray and method of use thereof  
A microarray device for the analysis of biological samples is provided. The device includes a liquid permeable layer having a plurality of microregions, each including a plurality of probe-labeled...
6326177 Method and apparatus for intracellular electro-manipulation  
A method for intracellular electro-manipulation is provided. The method includes applying at least one ultrashort electric field pulse to target cells. The ultrashort electric field pulse has...
US20010036965 Iodo-nonoxynol-9-derivatives and methods for their use  
Mono- and di-iodinated nonoxynol-9-derivatives and methods for their use are disclosed.
6281251 Iodo-nonoxynol-9-derivatives and methods for their use  
Mono- and di-iodinated nonoxynol-9-derivatives and methods for their use are disclosed.
Matches 1 - 50 out of 69 1 2 >