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7429458 |
Methods of using bioelastomers
Bioelastomers are disclosed for use in methods of binding compounds including immunoassay methods, in biosensors and methods or regenerating biosensors, and in methods for targeting the delivery of...
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7427932 |
Compressive sampling and signal inference
An optical signal is copressively sampled using an imaging system. The imaging system is created from a plurality of subimaging systems. Each subimaging system comprises a subaperture and a...
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7425445 |
Modulators that promote cell surface expression of odorant receptors
The present invention relates to polypeptides capable of promoting odorant receptor cell surface localization and odorant receptor functional expression. The present invention further provides...
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US20080213805 |
Method for Distinguishing Follicular Thyroid Adenoma (FTA) from Follicular Thyroid Carcinoma (FTC)
Follicular thyroid adenoma (FTA) is distinguished from follicular thyroid carcinoma (FTC) by comparing amount of an expression product of at least one gene selected from the group consisting of...
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US20080213296 |
Immunogen
The present invention relates, in general, to an immunogen for inducing antibodies that neutralize a wide spectrum of HIV primary isolates. The invention also relates to a method of inducing...
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7420724 |
Scanner apparatus having electromagnetic radiation devices coupled to MEMS actuators
A disclosed scanner apparatus includes a member having spaced apart proximal and distal portions. An electromagnetic radiation device is configured to direct electromagnetic radiation therefrom and...
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US20080207582 |
Substituted Porphyrins
A series of ortho isomers of meso tetrakis N-alkylpyridylporphyrins (alkyl being methyl, ethyl, n-propyl, n-butyl, n-hexyl, and n-octyl) and their Mn(III) complexes were synthesized and...
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US20080206738 |
Compositions and methods for modulating S-nitrosoglutathione reductase
Disclosed herein are methods and compositions for modulating the levels and/or activity of S-nitrosoglutathione reductase (GSNOR) in vivo or in vitro. Specifically disclosed are GSNOR deletion...
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US20080204762 |
Methods, systems, and computer program products for removing undesired artifacts in fourier domain optical coherence tomography (FDOCT) systems using integrating buckets
Methods, systems, and computer program products for removing undesired artifacts in Fourier domain optical coherence tomography (FDOCT) systems using integrating buckets are disclosed. According to...
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7417109 |
Polymers for delivering nitric oxide in vivo
Disclosed are novel polymers derivatized with at least one —NOx group per 1200 atomic mass unit of the polymer. X is one or two. In one embodiment, the polymer is an S-nitrosylated polymer and is p...
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7415143 |
Methods and systems for the detection of malignant melanoma
The present invention relates to the detection of malignant melanoma. In particular, the present invention relates to systems and methods for the early detection of cancerous lesions.
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7413906 |
Quantitative, high-throughput screening method for protein stability
In proteomic research, it is often necessary to screen a large number of polypeptides for the presence of stable structure. Described herein are methods (referred to as MALDI MS-HX and SUPREX) for...
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7413876 |
Expression of G protein coupled receptors in yeast
Disclosed is a transformed yeast cell containing a first heterologous DNA sequence which codes for a mammalian G protein-coupled receptor and a second heterologous DNA sequence which codes for a...
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7407987 |
Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins
A method for treating hair loss in mammals uses compositions containing prostaglandin F analogs. The compositions can be applied topically to the skin. The compositions can arrest hair loss,...
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US20080175833 |
Treatment of glycogen storage disease type II
Methods of treating glycogen storage disease type II, by administering acid α-glucosidase, are described, as are compositions for use in treatment of glycogen storage disease type II.
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US20080170219 |
Methods, systems, and computer program products for performing real-time quadrature projection based Fourier domain optical coherence tomography
Methods, systems, and computer program products for performing real-time quadrature projection based FDOCT are disclosed. According to one method, a plurality of interferogram signals is phase...
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7399957 |
Coded mass spectroscopy methods, devices, systems and computer program products
A coded mass spectrometer incorporates a spatial or temporal code to reduce the resolution/sensitivity dichotomy inherent in mass spectrometry. The code is used to code one or more portions of a...
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US20080166747 |
Biosensor
Biosensors are made by attaching covalently or non-covalently at least one reporter group to one or more specific positions of a bacterial periplasmic binding protein (bPBP). Upon binding of ligand...
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US20080160636 |
Isolated GRP94 ligand binding domain polypeptide and nucleic acid encoding same, and screening methods employing same
An isolated GRP94 ligand binding domain polypeptide. In some embodiments, the isolated GRP94 ligand binding domain polypeptide includes (a) an amino acid sequence encoded by a nucleic acid molecule...
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US20080145875 |
ANTI-TENASCIN MONOCLONAL ANTIBODY IMMUNOASSAYS AND DIAGNOSTIC KITS
The present invention provides immunoassays for detecting a tumor in a subject, comprising producing an antibody that specifically binds to tenascin, contacting the antibody with a biological...
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US20080145449 |
Thiol reactive agents as a therapeutic modality
A patient with a disease associated with a receptor having a cysteine residue is treated with a thiol reactive agent. The diseases include neurodegenerative diseases. Diseases characterized by...
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US20080141585 |
PLANT GROWTH AND IMAGING DEVICES AND RELATED METHODS AND COMPUTER PROGRAM PRODUCTS
A plant growth array device includes an aerial growth chamber configured to receive aerial shoot portions of a plurality of plants and a root growth chamber configured to receive root portions of...
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7388029 |
Compositions and methods for treating hair loss using non-naturally occurring prostaglandins
A method for treating hair loss in mammals uses compositions containing prostaglandin F analogs. The compositions can be applied topically to the skin. The compositions can arrest hair loss,...
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7384907 |
Method of treating infection with ABl tyrosine kinase inhibitors
The present invention relates to a method of preventing or treating a pathogen infection comprising administering to a mammal in need thereof an effective amount of an inhibitor of Abl tyrosine...
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US20080124742 |
Modulators of odorant receptors
The present invention relates to polypeptides capable of promoting odorant receptor cell surface localization and odorant receptor functional expression. The present invention further provides...
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US20080118505 |
Reagents and treatment methods for autoimmune diseases
The invention concerns treatment methods using anti-CD22 monoclonal antibodies with unique physiologic properties. In particular, the invention concerns methods for the treatment of B-cell...
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7374538 |
Methods, systems, and computer program products for ultrasound measurements using receive mode parallel processing
A pushing pulse is delivered from an ultrasound transducer array having a plurality of elements to a target region within a medium to displace the target region to a displaced position. A tracking...
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US20080113915 |
SAPAP3 knockout mouse and clinical modeling associated with the SAPAP3 gene
Provided is a transgenic knockout mouse whose genome includes a disruption in its endogenous SAPAP3 gene, wherein the disruption results in the mouse exhibiting increased levels of anxiety as...
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US20080113901 |
Use of an agent that restores tissue perfusion and oxygenation
The presently disclosed subject matter provides methods for increasing perfusion in hypoxic regions of tissues in subjects. Also provided are methods for treating diseases and/or disorders...
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7371522 |
Use of polymorphism of the serotonin transporter gene promoter as a predictor of disease risk
The present invention provides a method of screening subjects for disease risk. The method comprises determining the serotonin transporter gene promoter genotype of a subject. The serotonin...
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US20080107637 |
Use of an agent that restores tissue perfusion and oxygenation
The presently disclosed subject matter provides methods for increasing perfusion in hypoxic regions of tissues in subjects. Also provided are methods for treating diseases and/or disorders...
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US20080106732 |
STATIC TWO-DIMENSIONAL APERTURE CODING FOR MULTIMODAL MULTIPLEX SPECTROSCOPY
A class of aperture coded spectrometer is optimized for the spectral characterization of diffuse sources. The instrument achieves high throughput and high spatial resolution by replacing the slit...
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US20080103184 |
COMPOSITIONS AND METHODS FOR TREATING HAIR LOSS USING NON-NATURALLY OCCURRING PROSTAGLANDINS
A method for treating hair loss in mammals uses compositions containing prostaglandin F analogs. The compositions can be applied topically to the skin. The compositions can arrest hair loss,...
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7364859 |
Methods of using bioelastomers
Bioelastomers are disclosed for use in methods of binding compounds including immunoassay methods, in biosensors and methods or regenerating biosensors, and in methods for targeting the delivery of...
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US20080095751 |
Atherosclerosis
The present invention relates, in general, to atherosclerosis and, in particular, to a method of treating atherosclerosis and to cells suitable for use in such a method.
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US20080089846 |
SYSTEMS AND METHODS FOR ASSESSING PULMONARY GAS TRANSFER USING HYPERPOLARIZED 129XE MRI
Methods and systems for assessing pulmonary gas exchange and/or alveolar-capillary barrier status include obtaining at least one MRI image and/or image data of 129Xe dissolved in the red blood...
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7358234 |
Induction of a protective immune response through microprojectiles coated with a DNA sequence encoding an immunogenic protein
The present invention relates to a process for inducing a protective immune response in a mammal against a virus, in which a construct including a promoter and a DNA sequence encoding a protein or...
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7358043 |
Proteomic interaction and genomic action determinations in the presence of associated redox state conditions
Genomic actions and/or proteomic interactions for pathophysiological processes and for physiological processes are determined at associated redox state conditions. Protein interactions are...
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7355023 |
Isolated nucleic acids and polypeptides associated with glucose homeostasis disorders and method of detecting the same
An isolated and substantially pure nucleic acid sequence located between D20S119 and D20S178 on human chromosome 20q13, the nucleic acid sequence including: a nucleic acid sequence coding for a...
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US20080081345 |
Sour taste receptor compositions and methods
The present invention relates to sour taste receptors and compositions and methods thereof. In particular, the present invention provides assays and methods of screening for ligands specific for...
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7351975 |
Sensor system for identifying and tracking movements of multiple sources
A system identifies a human being from the movement of the human being. The system includes a dual element pyroeleetric detector, a Fresnel lens array, and a processor. The dual element...
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US20080064709 |
METHODS AND COMPOSITIONS FOR THE TREATMENT OF VASCULAR DEPRESSION
Methods and compositions are provided for treating vascular depression. The methods involve administering to a subject in need thereof a xanthine derivative in a therapeutically effective amount to...
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US20080058372 |
Synthesis and antimicrobial activity of novel dicationic ''reversed amidines''
The present invention relates to novel 2,5-bis{[alkyl(or aryl)imino]aminophenyl}furans and thiophenes of the general formula in which R1, R2, R3 and R4 are each independently selected from the...
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US20080057048 |
Aggregate-free urate oxidase for preparation of non-immunogenic polymer conjugates
A naturally occurring or recombinant protein, especially a mutein of porcine urate oxidase (uricase), that is essentially free of large aggregates can be rendered substantially non-immunogenic by...
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7338670 |
Use of an agent that restores tissue perfusion and oxygenation
The presently disclosed subject matter provides methods for increasing perfusion in hypoxic regions of tissues in subjects. Also provided are methods for treating diseases and/or disorders...
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US20080051339 |
Modulators of pharmacological agents
The biological activity of nucleic acid ligand is regulated (i.e. enhanced or inhibited) in vivo to produce a desired biological effect. This is accomplished through the administration of a...
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7336366 |
Methods and systems for reducing complex conjugate ambiguity in interferometric data
A complex conjugate ambiguity can be resolved in an Optical Coherence Tomography (OCT) interferogram. A reference light signal is propagated along a reference path. A sample light signal is...
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7336353 |
Coding and modulation for hyperspectral imaging
Embodiments of the present invention relate to systems and methods for spectral imaging. In one embodiment, an image of the scene is formed on a coded aperture of a spectrometer. A coded image from...
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US20080038842 |
SLITRK1 mutations associated with disorders in the OCD spectrum
The present invention provides compositions and methods directed to the use of SLITRK1 (slit and trk like 1) mutations to identify, diagnose, and treat disorders in the obsessive-compulsive...
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US20080038365 |
TRPC6 involved in glomerulonephritis
Focal and segmental glomerulosclerosis (FSGS) is a kidney disorder of unknown etiology and up to 20% of patients on dialysis have this diagnosis. A large family with hereditary FSGS carries a...
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