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US20040230263 |
Non-invasive apparatus and method for providing RF energy-induced localized hyperthermia
An apparatus for providing hyperthermia treatment for enhancing cancer therapy includes an applicator body and a plurality of antennas operatively associated with the applicator body. The...
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US20040229290 |
Protein design for receptor-ligand recognition and binding
We describe processes for the protein structure-based design or redesign of receptor-ligand interfaces (ligand-binding sites) in which a ligand is recognized and bound. Receptors designed in this...
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US20040228847 |
Progenitor cells and methods of using same
The present invention relates generally to stem/progenitor cells and, in particular, to therapeutic strategies based on the use of such cells to effect vascular rejuvenation and/or to serve as...
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US20040224382 |
Device for containing and analyzing surgically excised tissue and related methods
A collection device and method of use for excised tissue immobilization, removal of core samples from immobilized tissue and transport of the tissue for specimen radiography and pathological...
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US20040223162 |
Fourier domain low-coherence interferometry for light scattering spectroscopy apparatus and method
An apparatus and method for obtaining depth-resolved spectra for the purpose of determining the size of scatterers by measuring their elastic scattering properties. Depth resolution is achieved by...
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US20040213361 |
Methods and systems for determining an optimal training interval in a communications system
Methods and Systems for Determining an Optimal Training Interval in a Communications System. A method is provided for determining an optimal training interval for a channel of a communications...
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6808897 |
Method of nucleic acid sequencing
The present invention relates, in general, to a process of enzymatically synthesizing nucleic acids containing nucleotides that are resistant to degradation. The invention further relates to...
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US20040209308 |
Methods of assaying receptor activity and constructs useful in such methods
Described are methods of detecting G-protein coupled receptor (GPCR) activity in vivo and in vitro; methods of assaying GPCR activity; and methods of screening for GPCR ligands, G protein-coupled...
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US20040207855 |
Methods and systems for static multimode multiplex spectroscopy
Methods and systems for static multimode multiplex spectroscopy are disclosed. According to a method for static multimode multiplex spectroscopy, spectral energy emanating from different points of...
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US20040202675 |
Vaccine adjuvant
The present invention relates generally to K12 and more specifically to the use of K12 as a non-antigen specific activator of immune function.
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US20040198668 |
Method for treating obesity
The present invention relates, in general, to obesity, and, in particular, to a method of treating obesity and minimizing metabolic risk factors associated therewith using, for example, zonisamide...
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US20040197344 |
Human immunodeficiency virus vaccine
The present invention relates, in general, to human immunodeficiency virus (HIV) and, in particular, to an HLA-based HIV vaccine.
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US20040196304 |
Mixed mode grayscale method for display system
A method for generating a grayscale representation for a display combines analog and digital techniques to produce images of optimal quality. The grayscale representation is not limited by frame...
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6797265 |
Deleted adenovirus vectors and methods of making and administering the same
The present invention provides deleted adenovirus vectors. The inventive adenovirus vectors carry one or more deletions in the IVa2, 100K, polymerase and/or preterminal protein sequences of the...
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6788460 |
Projection screen apparatus
Screen apparatuses are provided which include a first lens or holographic optical element layer and a second mask layer. The first layer substantially collimates image light rays to impinge on the...
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6787527 |
Methods of preventing and treating HIV infection
The present invention relates, in general, to a method of preventing or treating human immunodeficiency virus (HIV) infection, and in particular, to a method of preventing or treating HIV infection...
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US20040170616 |
Particle-mediated transformation of animal tissue cells
A method of transferring a gene to vertebrate cells is disclosed. The method comprises the steps of: (a) providing microprojectiles, the microprojectiles carrying polynucleic acid sequences, the...
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6784898 |
Mixed mode grayscale method for display system
A method for generating a grayscale representation for a display combines analog and digital techniques to produce images of optimal quality. The grayscale representation is not limited by frame...
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6783964 |
Microencapsulated pancreatic islet cells
Methods of treating and forming biocompatible microcapsules that contain living cells are provided, to improve the function of the microcapsules. In particular, methods of treating islet cells or...
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US20040167800 |
Methods and systems for searching, displaying, and managing medical teaching cases in a medical teaching case database
Methods and Systems for Searching, Displaying and Managing Medical Teaching Cases in a Medical Teaching Case Database. A method is provided for displaying relevant medical teaching cases in a...
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US20040151666 |
Rodent mammary window for intravital microscopy of orthotopic breast cancer and related method
A rodent mammary window for intravital microscopy of orthotopic breast cancer and the related method of use in rodents to provide a useful model to investigate the cellular behavior of implanted...
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6771339 |
Methods of compensating liquid crystal displays using DC balancing
In a reflective mode FLC application, a ¼-wave plate compensating FLC is used in series with a ¼-wave imaging FLC to compensate for the effects of DC balancing. Alternatively, the compensating w...
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6770449 |
Methods of assaying receptor activity and constructs useful in such methods
Described are methods of detecting G-protein coupled receptor (GPCR) activity in vivo and in vitro; methods of assaying GPCR activity; and methods of screening for GPCR ligands, G protein-coupled...
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6770039 |
Method to reduce tissue injury in shock wave lithotripsy
A method to reduce vascular injury produced by lithotripter shock waves comprising the use of particular multi-pulsed shock waves which comminute human concretions with reduced vascular damage.
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6768566 |
Projection screen apparatus including holographic optical element
A screen apparatus includes a holographic optical element and a diffuser. The holographic optical element may be constructed using standard techniques known in the field of holography. The...
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US20040142368 |
Method of identifying therapeutic agents
The present invention relates to a method of identifying agents suitable for use in treating epilepsy and other brain disorders, including but not limited to bipolar disorder, schizophrenia and...
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6764448 |
Methods, systems, and computer program products for imaging using virtual extended shear wave sources
Ultrasound energy is transmitted into tissue in a first direction to provide a virtual extended shear wave source. The virtual extended shear wave source generates an extended shear wave that...
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US20040132904 |
Novel polymers for delivering nitric oxide in vivo
Disclosed are novel polymers derivatized with at least one —NOx group per 1200 atomic mass unit of the polymer. X is one or two. In one embodiment, the polymer is an S-nitrosylated polymer and is p...
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US20040132638 |
No-modified hemoglobins and uses therefor
Nitrosylhemoglobin can be produced by introducing gaseous NO into an aqueous solution of hemoglobin. It has been demonstrated that nitrosylhemoglobin in aqueous solution can be converted to...
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US20040132010 |
Immunogen
The present invention relates, in general, to an immunogen and, in particular, to an immunogen for inducing antibodies that neutralize a wide spectrum of HIV primary isolates. The invention also...
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US20040131619 |
Thymic atrophy
The present invention relates, in general, to thymic atrophy and, in particular, to a method of treating or preventing thymic atrophy in septic shock.
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US20040115174 |
Angio-immunotherapy
The present invention relates, in general, to cancer therapy and, in particular, to a method of treating cancer that involves immunization against an endothelial-specific product preferentially...
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6746122 |
Image projection system engine assembly
A light projection engine uses a wide angle reflecting polarizer material (preferably 3M DBEF brand double brightness enhancement filter) as a polarizing beamsplitter to direct polarized light to...
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US20040101969 |
Methods and compositions for blood pool identification, drug distribution quantification and drug release verification
Methods and compositions useful for detecting an in vivo blood pool, monitoring the distribution of a compound of interest to a desired site in an organism by magnetic resonance imaging, monitoring...
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US20040101887 |
Methods of assaying receptor activity and constructs useful in such methods
Described are methods of detecting G-protein coupled receptor (GPCR) activity in vivo and in vitro; methods of assaying GPCR activity; and methods of screening for GPCR ligands, G protein-coupled...
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US20040097458 |
Particle-mediated transformation of animal tissue cells
A method of transferring a gene to vertebrate cells is disclosed. The method comprises the steps of: (a) providing microprojectiles, the microprojectiles carrying polynucleic acid sequences, the...
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US20040095626 |
Reference structures and reference structure enhanced tomography
A reference structure tomography device is provided which includes a reference structure configured to intercept and modulate energy in the form of waves or otherwise propagating from a source to a...
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6737440 |
Synthesis and antimicrobial activity of novel dicationic “reversed amidines”
The present invention relates to novel 2,5-bis {[alkyl(or aryl)imino]aminophenyl}furans and thiophenes of the general formula in which R1, R2, R3 and R4 are each independently selected from the...
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US20040092019 |
Particle-mediated transformation of animal tissue cells
A method of transferring a gene to vertebrate cells is disclosed. The method comprises the steps of: (a) providing microprojectiles, the microprojectiles carrying polynucleic acid sequences, the...
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6734023 |
Quantitative, high-throughput screening method for protein stability
In proteomic research, it is often necessary to screen a large number of polypeptides for the presence of stable structure. Described herein are methods (referred to as MALDI MS-HX and SUPREX) for...
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US20040086506 |
Polyvalent immunogen
The present invention relates, generally, to a polyvalent immunogen and, more particularly, to a method of inducing neutralizing antibodies against HIV and to a polyvalent immunogen suitable for...
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US20040086479 |
Novel dendritic polymers, crosslinked gels, and their biomedical uses
Crosslinkable polymers, such as dendritic macromolecules and their in vitro, in vivo, and in situ uses are disclosed. These biomaterials/polymers are likely to be an effective sealant/glue for a...
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6726925 |
Temperature-sensitive liposomal formulation
A liposome contains an active agent and has a gel-phase lipid bilayer membrane comprising phospholipid and a surface active agent. The phospholipids are the primary lipid source for the lipid...
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US20040076610 |
Method of treating portal hypertension
The present invention relates, in general, to portal hypertension and, in particular, to a method of reducing portal hypertension using an isoform of nitric oxide synthase.
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6723703 |
Therapeutic use of aerosolized S-nitrosoglutathione in cystic fibrosis
The present invention is directed to the treatment of cystic fibrosis that involves the administration of a nitrosylating agent, such as S-nitrosoglutathione or ethyl nitrite.
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6723534 |
Purified and isolated PIWI family genes and gene products and therapeutic and screening methods using same
A family of isolated and purified proteins and nucleic acids are disclosed. Particularly, piwi family proteins and cDNAs encoding the same are disclosed. Recombinant host cells, recombinant nucleic...
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US20040058902 |
Substituted porphyrins
A series of ortho isomers of meso tetrakis N-alkylpyridylporphyrins (alkyl being methyl, ethyl, n-propyl, n-butyl, n-hexyl, and n-octyl) and their Mn(III) complexes were synthesized and...
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6711436 |
Compositions, apparatus and methods for facilitating surgical procedures
Methods are provided for conducting diagnostic or therapeutic medical or surgical procedures in a patient wherein, during the procedure, autonomous ventricular electrical conductivity and escape...
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US20040053411 |
Method of regulating gene expression
The present invention relates, in general, to gene expression and, in particular, to a method of inhibiting the expression of a target gene and to constructs suitable for use in such a method.
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US20040052820 |
Fusion proteins comprising DP-178 and other viral fusion inhibitor peptides useful for treating aids
The present invention relates to peptides which exhibit potent anti-retroviral activity. The peptides of the invention comprise DP178 (SEQ ID:1) peptide corresponding to amino acids 638 to 673 of...
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