Patents and Patent Applications from Drexel University


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US20120034244 METHODS OF TREATING SECONDARY BONE TUMORS WITH ANTIBODIES AGAINST PDGFR ALPHA  
The invention provides methods of treating bone cancer, particularly metastatic bone cancer, by administering an IGF-IR antagonist and/or a PDGFRα antagonist. The invention also provides ...
8110964 Energy harvesting device  
A piezoelectric energy harvesting device (PEHD) comprising a driving element, conducting element, piezoelectric layer and non-piezoelectric layer capable of converting ambient mechanical energy...
8110212 Bioactive thermogelling polymer systems and methods of their use  
Hydrogels comprising poly(N-alkylacrylamide), poly(alkyleneglyco)di-acrylate or methacrylate, cross-linking agent, a source of calcium ions, and water are described, as well as methods of their...
8110155 Vortex reactor and method of using it  
A vortex reactor is provided. The vortex reactor includes a reaction chamber formed by a frustum-shaped portion, the narrower part of which is downwardly oriented. Proximate to the narrower part of...
8104124 Two-piece lightweight litter system  
This invention is directed to a durable, compact, two-piece, light weight, load sustaining litter system for the transport of humans, animals or objects. The litter system comprises a litter frame,...
8093046 CVN-12p1: a recombinant allosteric lectin antagonist of HIV-1 envelope gp120 interactions  
The invention provides a recombinant multi-functional chimera of CVN and 12p1. Chimeras of CVN and 12p1 present a model for targeting gp120 at two discrete sites, by two different modes of...
8086316 Wireless controlled neuromodulation system  
An apparatus is disclosed for controlled neuromodulation. The apparatus includes a plurality of neural sensors, wherein each of the neural sensors is electrically connected to a separate signal...
US20110313022 Compositions and Methods for Diminishing Viral Infection and Inflammation Associated with Viral Infection  
The invention relates to compositions and methods for preventing and diminishing virus infection. The invention further relates to compositions and methods for diminishing inflammation associated...
8080229 Water soluble nanocrystalline quantum dots  
An economic, direct synthetic method for producing water soluble QDs that are ready for bioconjugation is provided. The method can produce aqueous QDs with emission wavelengths varying from 400 nm...
US20110305837 POLY(ETHYLENE GLYCOL) AND POLY(ETHYLENE OXIDE) BY INITIATED CHEMICAL VAPOR DEPOSITION  
A method for ionic polymerization of ethylene oxide. In the first step of the method, a gaseous monomer composition comprising ethylene oxide at a first flow rate is mixed with a gaseous ionic...
US20110305118 Fiber Optic Hydrophone Sensors And Uses Thereof  
Disclosed is detecting changes in pressure in a medium, with an optical fiber having a core diameter at an immersion surface contact of the fiber of less than 10 μm; a layer of material deposited ...
US20110295903 SYSTEM AND METHOD FOR AUTOMATICALLY GENERATING SYSTEMATIC REVIEWS OF A SCIENTIFIC FIELD  
A system and method are provided for automatically generating systematic reviews of received information in a field of science and technology, such as scientific literature, where the systematic...
US20110288199 Fiber-Hydrogel Composite for Tissue Replacement  
The present invention includes tailored fiber-reinforced hydrogel composites for implantation into a subject. The present invention also includes systems and methods for controlling the relative...
US20110277618 METHOD AND APPARATUS FOR BRAIDING MICRO STRANDS  
A method and apparatus for fabricating microbraided structures is provided. A microbraiding device includes first and second carrier members that are movable with respect to each other. Each...
US20110270400 PHASE TRANSITIONING HYDROGELS  
A method of forming and the resulting hydrogel composition comprising poly(vinyl alcohol) at a final concentration of about 20% (w/w) to about 65% (w/w) and polyethylene glycol at a final...
8048949 Composite repair resins containing minimal hazardous air pollutants and volatile organic compound  
The present invention relates to a composition and method for fabricating composite resins that produce either reduced or zero volatile organic compound (VOC) and zero hazardous air pollutant (HAP)...
8048446 Electrospun blends of natural and synthetic polymer fibers as tissue engineering scaffolds  
Non-woven fibrous scaffolds made by electrospinning from the synthetic biodegradable polymer such as, for example, poly(lactic-co-glycolic acid) (PLGA) and natural proteins, such as, for example,...
US20110265227 PIEZOELECTRIC MICROCANTILEVERS AND USES IN ATOMIC FORCE MICROSCOPY  
The invention is direct to a piezoelectric microcantilever for static contact and dynamic noncontact atomic force microscopy which may be carried out in solution. The piezoelectric microcantilever,...
US20110264117 TISSUE JOINING DEVICE AND INSTRUMENT FOR ENABLING USE OF A TISSUE JOINING DEVICE  
A tissue joining device and a surgical instrument for employing the tissue joining device are provided. The tissue joining device may be designed such that a first member may be inserted into a...
US20110260946 MIMO ANTENNA ARRAYS BUILT ON METAMATERIAL SUBSTRATES  
A magnetic permeability enhanced metamaterial is used to enhance the antenna array of a Multiple Input Multiple Output (MIMO) communication system. A rectangular patch antenna array is formed...
US20110260109 WATER SOLUBLE NANOCRYSTALLINE QUANTUM DOTS  
An economic, direct synthetic method for producing water soluble QDs that are ready for bioconjugation is provided. The method can produce aqueous QDs with emission wavelengths varying from 400 nm...
US20110257320 COMPOSITE REPAIR RESINS CONTAINING MINIMAL HAZARDOUS AIR POLLUTANTS AND VOLATILE ORGANIC COMPOUND  
The present invention relates to a composition and method for fabricating composite resins that produce either reduced or zero volatile organic compound (VOC) and zero hazardous air pollutant (HAP)...
US20110256538 EPIGENOMIC DNA MODIFICATIONS FOR TISSUE TYPING, EARLY CANCER DETECTION, AND DISEASE MANAGEMENT  
Provided herein is a suitable method for detecting the presence or absence of a cancer in an individual, by determining the level of methylation of the sense strand of a selected regulatory region...
8038926 Method for making carbon nanotubes with embedded nanoparticles  
The invention concerns methods for producing carbon nanotubes with embedded nanoparticles comprising providing a template comprising an anodized aluminum oxide membrane with a pore diameter of...
US20110251604 NANO DISCHARGES IN LIQUIDS  
The present invention is direct to a nano-probe corona tool and uses thereof. A nano-probe corona tool is disclosed having a tip with a diameter in the nano-scale, typically around 100 nm. The...
8033185 All electric piezoelectric finger sensor (PEFS) for soft material stiffness measurement  
A PEFS (Piezoelectric Finger Sensor) acts as an “electronic finger” capable of accurately and non-destructively measuring both the Young's compression modulus and shear modulus of tissues with gen...
US20110246636 Efficient Distributed Algorithm for the Location Design and Routing Problem  
The Location Design and Routing problem asks to find a subset of “depot” nodes and a spanning forest of a graph such that every connected component in the forest contains at least one depot. Thi...
US20110243982 Chimeric MSP-Based Malaria Vaccine  
The invention provides an immunogenic composition comprising MSP-8 linked to an antigen. Methods of using the composition to induce an immune response in an animal are also provided.
US20110226610 SYNTHESIS OF NITRODIBENZYLFURAN CHROMOPHORE FOR PHOTODEPROTECTION OF ORGANIC MOLECULES  
Inventors have developed a chromophore (nitrodibenzylfuranyl, or NBDF) for ultra efficient uncaging of a caged substrate (e.g., an organic molecule such as, for example, an amino acid, a biological...
8015125 Multi-scale segmentation and partial matching 3D models  
A scale-Space feature extraction technique is based on recursive decomposition of polyhedral surfaces into surface patches. The experimental results show that this technique can be used to perform...
8010296 Apparatus and method for removing non-discriminatory indices of an indexed dataset  
The present invention provides a device and method for removing non-discriminatory indices of an indexed dataset using ensemble statistics analysis. The device may include a data removal module...
US20110208063 NON-CONTACT FREQUENCY DOMAIN NEAR INFRARED ABSORPTION (fNIR) DEVICE FOR ASSESSING TISSUE DAMAGE  
A device for measuring the progress of healing of a wound over time includes at least one diode laser source that provides respective input wavelengths into at least one source fiber, a first...
US20110207129 METHODS OF DIAGNOSING NON-URINARY TRACT DISEASES BY DETECTING ABERRANT METHYLATION  
Provided are methods of diagnosing and/or determining treatment of non-urinary tract cancers by detecting biomarkers, and aberrant methylation in said biomarkers, in human urine samples
US20110199563 Polymer Dispersed Liquid Crystal Photovoltaic Device and Method for Making  
A novel photovoltaic device including a polymer dispersed liquid crystal (PDLC) material that is capable of converting solar energy to electrical energy and method for making. The device may...
US20110192789 METAL OR METAL OXIDE DEPOSITED FIBROUS MATERIALS  
A method for electrospraying nanosized metal or metal oxide particles onto a substrate. A metal oxide deposited fibrous material comprising a substrate, fibers and metal oxide particles may be made...
7993854 Detection and quantification of biomarkers via a piezoelectric cantilever sensor  
Quantification of a target analyte is performed using a single sample to which amounts of the target analyte are added. Calibration is performed as part of quantification on the same sample. The...
7992431 Piezoelectric microcantilevers and uses in atomic force microscopy  
The invention is direct to a piezoelectric microcantilever for static contact and dynamic noncontact atomic force microscopy which may be carried out in solution. The piezoelectric microcantilever,...
US20110177590 Bioprinted Nanoparticles and Methods of Use  
The present invention provides compositions and methods that combine the initial patterning capabilities of a direct cell printing system with the active patterning capabilities of magnetically...
US20110175183 INTEGRATED PLASMONIC LENS PHOTODETECTOR  
Metal-semiconductor-metal (MSM) photodetectors may see increased responsivity when a plasmonic lens is integrated with the photodetector. The increased responsivity of the photodetector may be a...
US20110172565 SYSTEM AND METHOD FOR EVALUATING TISSUE  
A sensor system for measuring an elastic modulus and a shear modulus and a method for evaluating a tissue. The invention pertains to a method for determining the presence of and/or characterizing...
US20110172268 MECHANISM-BASED SMALL-MOLECULE PARASITE INHIBITORS  
Methods for preventing or treating an Apicomplexan parasite infection in a patient administering to a patient in need thereof an effective amount of a compound of Formulas I-IV.
US20110171203 METHODS FOR TREATING NEOPLASTIC DISEASE TARGETING O-LINKED N-ACETYLGLUCOSAMINE MODIFICATIONS OF CELLULAR PROTEIN  
Methods for treating a neoplastic disease in a mammalian subject are provided. The method provides administering an inhibitor of O-GlcNAc transferase in an amount effective to reduce or eliminate...
7976819 Water soluble nanocrystalline quantum dots  
An economic, direct synthetic method for producing water soluble QDs that are ready for bioconjugation is provided. The method can produce aqueous QDs with emission wavelengths varying from 400 nm...
7975547 Method and apparatus for interfacial sensing  
A sensor is disclosed for analyzing information, such as interfacial interactions, found in various systems. A sensor is located proximate to an interface that is to be studied. The sensor is...
US20110165646 Super Sparger Microcarrier Beads and Precision Extrusion Deposited Poly-Epsilon-Caprolactone Structures for Biological Applications  
In on aspect, the invention includes a microcarrier bead having a porous three-dimensional core having (a) a polymeric porous three-dimensional body having porosity of about 15 to about 90% such...
US20110159109 TITANIA DISPERSION AND METHOD FOR MAKING  
A novel method for preparing a titania dispersion by blending two different titania dispersions synthesized by a solvothermal process and a hydrolysis process. The titania dispersion has a...
US20110154903 METHOD FOR STRUCTURAL HEALTH MONITORING USING A SMART SENSOR SYSTEM  
The structural health monitoring method of the present invention utilizes ultrasound to determine information about deformation, stress and/or damage in structural elements. The method propagates...
US20110153022 BALLOON-ASSISTED ANNULUS REPAIR  
The present invention is directed to an inflatable annulus repair device (10) for sealing an annulus defect located in an annulus fibrosis of an intervertebral disc space. In use, the inflatable...
7964159 Nanotube-based sensors and probes  
Described herein are novel devices for the study of transport characteristics of complex or simple fluids, interactions among molecules in suspension, interactions between molecules in suspension...
US20110138916 SELF-EXCITING, SELF-SENSING PIEZOELECTRIC CANTILEVER SENSOR  
A piezoelectric cantilever sensor includes a piezoelectric layer and a non-piezoelectric layer, a portion of which is attached to the piezoelectric layer. In one embodiment, one end of the...
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