Patents and Patent Applications from Drexel University


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US20170294546 Physical Forms of MXene Materials Exhibiting Novel Electrical and Optical Characteristics  
The present invention(s) is directed to novel conductive Mn+1Xn(Ts) compositions exhibiting high volumetric capacitances, and methods of making the same. The present invention(s) is also directed...
US20170281589 USE OF STING AGONISTS TO TREAT CHRONIC HEPATITIS B VIRUS INFECTION  
Provided herein are methods of treating a subject having hepatitis B viral (HBV) infection. More specifically, disclosed herein are methods of stimulating the innate cytokine response in...
9773079 Methods and computer-readable media for synthesizing a multi-corner mesh-based clock distribution network for multi-voltage domain and clock meshes and integrated circuits  
One aspect of the invention provides a including: (a) placing N×N max size buffers at an (n−1)st level of one of the voltage domains i until a maximum slew slewmax within the voltage domain i...
US20170266223 NOVEL METHODS OF PREPARING BIOMIMETIC PROTEOGLYCANS  
The present invention novel methods of preparing biomimetic proteoglycans, such as bottle-brush, chondroitin sulfate-containing, biomimetic proteoglycans. In certain embodiments, the methods of...
9758780 Whole genome mapping by DNA sequencing with linked-paired-end library  
The present invention relates to innovative means of generating sequence-linked DNA fragments and subsequent uses of such linked DNA fragments for de novo haplotype-resolved whole genome mapping...
9758477 Sulfamoylbenzamide derivatives as antiviral agents against HBV infection  
The present invention provides sulfamoylbenzamide derivatives, and pharmaceutical compositions thereof. In certain embodiments, the compounds and pharmaceutical compositions of the invention...
US20170254782 Identification of Water Pipe Material Based on Stress Wave Propagation  
A nondestructive evaluation method for determining the material used in a below ground service line includes inserting a probe with a wave measurement device therein into an area corresponding to...
9752932 Tunable electro-optic filter stack  
A holographic polymer dispersed liquid crystal (HPDLC) tunable filter exhibits switching times of no more than 20 microseconds. The HPDLC tunable filter can be utilized in a variety of...
9750742 Small molecular inhibitors of RAD51 recombinase and methods thereof  
The invention includes compositions comprising a selective small-molecule inhibitor of RAD51 recombinase and a pharmaceutically acceptable carrier. The invention further includes methods of...
US20170247758 METHODS, COMPUTER-READABLE MEDIA, AND SYSTEMS FOR ASSESSING SAMPLES AND WOUNDS, PREDICTING WHETHER A WOUND WILL HEAL, AND MONITORING EFFECTIVENESS OF A TREATMENT  
One aspect of the invention provides a method of predicting whether a wound will heal. The method includes: obtaining a first measurement of a first macrophage phenotype population within a first...
US20170247499 Toughening of Epoxy Thermosets  
Grafted triglycerides comprising a triglyceride grafted with a fatty acid residue containing 4 to 30 carbon atoms are reacted with an epoxide resin and an amine curing agent to yield an epoxy...
US20170246128 NOVEL D3 DOPAMINE RECEPTOR AGONISTS TO TREAT DYSKINESIA IN PARKINSON'S DISEASE  
The present invention provides a method of inhibiting, suppressing or preventing levodopa-induced dyskinesia in a patient suffering from Parkinson's Disease, comprising the step of administering...
9744262 Alimentary protein-based scaffolds (APS) for wound healing, regenerative medicine and drug discovery  
The invention provides engineered biomaterials derived from plant products. The engineered biomaterials are useful for biomedical applications. The engineered biomaterials are able to support the...
US20170240600 TAGGED HEPADNAVIRUS E ANTIGEN AND ITS USE IN SCREENING ANTIVIRAL SUBSTANCES  
The present invention relates to methods and uses for screening anti-hepadnaviral substances, wherein the substances are screened for the capacity to inhibit covalently closed circular (ccc) DNA...
US20170236955 Method for Making Ferroelectric Material Thin Films  
A method of growing a FE material thin film using physical vapor deposition by pulsed laser deposition or RF sputtering is disclosed. The method involves creating a target to be used for the...
9729765 Mobile virtual cinematography system  
A virtual cinematography system (SmartVCS) is disclosed, including a mobile tablet device, wherein the mobile tablet device includes a touch-sensor screen, a first hand control, a second hand...
9725693 Three-dimensional scaffolds for tissue engineering made by processing complex extracts of natural extracellular matrices  
Methods of making a biologically active three-dimensional scaffold capable of supporting growth and differentiation of a cell are described. Biologically active three-dimensional scaffold made by...
US20170212121 CAPPED AND CONJUGATED QUANTUM DOTS  
One or more aqueous, near infrared emitting, high yield, highly photoluminescent, stable quantum dots conjugated to one or more biomarkers specific moieties. The conjugated quantum dots have an...
US20170205389 All Electric Piezoelectric Finger Sensor (PEFS) for Soft Material Stiffness Measurement  
A PEFS (Piezoelectric Finger Sensor) acts as an “electronic finger” capable of accurately and non-destructively measuring both the Young's compression modulus and shear modulus of tissues with...
US20170204434 Maximizing Production of Hydrogen From Waste Materials by Active Removal of Hydrogen  
The present invention provides a method of producing hydrogen from a waste material, comprising steps of fermenting 100 a fermentation mixture comprising the waste material in a reactor 1 with a...
US20170204089 NOVEL COMPOUNDS AND METHODS OF TREATING OR AMELIORATING AN IL-1R-MEDIATED DISEASE OR DISORDER USING SAME  
The present invention provides compounds useful for treating or preventing an IL-1R-mediated disease or disorder. In certain embodiments, the disease or disorder comprises scleroderma.
US20170202218 Materials for Disinfection Produced by Non-Thermal Plasma  
Aspects of the present subject matter are directed to a method comprising contacting an fluid, optionally containing an added organic material, with a non-thermal plasma to form a disinfection...
US20170199076 Fiber Optic Hydrophone Sensors and Uses Thereof  
A sensing method is based on using a special fiberoptic probe for detection of acoustic/ultrasound pressure in an immersion medium. The developed system is highly sensitive in detecting ultrasound...
9700640 Stabilized ultrasound contrast agent  
Provided is a particle-stabilized ultrasound contrast agent (UCA) and methods of preparing same. Also provided is a method for preparing a lyoprotected UCA, a freeze-dried lyoprotected UCA, and a...
US20170190709 NOVEL COMPOSITIONS USEFUL IN TREATING BRAIN-RELATED DISEASES OR DISORDERS AND METHODS USING SAME  
The present invention provides compounds useful for treating or preventing a brain-related disease or disorder. The present invention further provides a method of treating or preventing a...
9695068 Pre-treating water with non-thermal plasma  
The present invention consists of a method of pre-treatment of adulterated water for distillation, including adulterated water produced during hydraulic fracturing (“fracking”) of shale rock...
US20170180420 Reconfigurable Antenna Based Solutions For Device Authentication And Intrusion Detection In Wireless Networks  
Channel based authentication schemes for intrusion detection that operates at the physical layer are described that apply the capabilities of a pattern reconfigurable antenna for improved...
US20170179613 Reconfigurable Antennas And Configuration Selection Methods For Ad-Hoc Networks  
Reconfigurable antennas in an ad-hoc network are provided where all nodes employ MIMO/SIMO/MISO communication techniques. Three types of reconfigurable antennas: Reconfigurable Printed Dipole...
US20170176799 DYNAMIC TIME MULTIPLEXING FABRICATION OF HOLOGRAPHIC POLYMER DISPERSED LIQUID CRYSTALS FOR INCREASED WAVELENGTH SENSITIVITY  
Described herein is a new holographic polymer dispersed liquid crystal (HPDLC) medium with broadband reflective properties, and a new technique for fabrication of broadband HPDLC mediums. The new...
US20170176475 NOVEL METHODS AND KITS FOR DETECTING A RIFAMYCIN, OR DERIVATIVE OR ANALOGUE THEREOF  
The present invention includes methods of identifying one or more rifamycins, or analogues or metabolites thereof, that are present in a biological sample from a subject that is being administered...
US20170169912 NOVEL APPLICATIONS FOR ALLIFORM CARBON  
This invention relates to novel applications for alliform carbon, useful in conductors and energy storage devices, including electrical double layer capacitor devices and articles incorporating...
US20170168565 Wearable Devices, Wearable Robotic Devices, Gloves, and Systems, Methods, and Computer Program Products Interacting with the Same  
One aspect of the invention provides a wearable device including: at least one compliant region adapted and configured to be placed over a joint of a subject and at least two flexible but less...
9675565 D3 dopamine receptor agonists to treat dyskinesia in parkinson's disease  
The present invention provides a method of inhibiting, suppressing or preventing levodopa-induced dyskinesia in a patient suffering from Parkinson's Disease, comprising the step of administering...
US20170163354 System For Ultrasonic Communication Across Curved Metal Surfaces  
Ultrasonic through metal communication systems are an effective solution for transmitting data across a metal barrier when the structural integrity of the barrier cannot be compromised by...
US20170160165 Self-Contained Rapid Modal Testing System for Highway Bridges  
A system for measuring structural integrity includes a self-contained rapid modal testing trailer that delivers an impact load to a structure being tested and records data resulting from the...
9668846 Textile-templated electrospun anisotropic scaffolds for tissue engineering and regenerative medicine  
The present invention includes an anisotropic scaffold, which is prepared by electrospinning a solution of matrix material upon a textile template. The present invention further includes a method...
9663372 Disaggregation of aggregated nanodiamond clusters  
The present invention is directed to methods of disaggregating nanodiamond clusters, especially those clusters typically produced from detonation syntheses, the nanodiamond particles and...
9662012 Apparatus and method for assessing effects of drugs by recording ocular parameters  
The invention is directed to quantification of the effects of drugs on a patient using pupillometric measures. Apparatus and processes for obtaining control and patient measures and deriving...
9657013 Inhibitors of hepatitis B virus covalently closed circular DNA formation and their method of use  
Pharmaceutical compositions of the invention comprise covalently closed circular DNA formation inhibitors having a disease-modifying action in the treatment of diseases associated with the...
US20170136120 INDUCTION OF IMMUNE RESPONSE  
Provided are methods and compositions that can he used to treat subjects having a viral infection by provoking an immune response using newly discovered antigens that are non-naturally occurring...
9644850 Heat pump water heater  
An energy efficient heat pump system capable of operating in extreme low and high temperature environments. The heat pump system includes an evaporator, a heater operatively associated with the...
9644059 Renewable bio-based (meth)acrylated monomers as vinyl ester cross-linkers  
Anhydrosugar-based monomers prepared from isosorbide, isomannide, and isoidide and resin systems containing these anhydrosugar-based monomers that are partially to fully bio-based, which may...
9642830 Use of sting agonists to treat hepatitis B virus infection  
The invention includes methods of treating a subject having hepatitis B viral (HBV) infection. In certain embodiments, the method of the invention comprises stimulating the innate cytokine...
US20170112971 BIOTIN-AVIDIN CONTROLLED DELIVERY SYSTEMS  
The application relates to the delivery of immunomodulatory molecules, including cytokines, to the situs of tissue scaffolds, and wounds including injuries.
US20170109879 COMPUTER-IMPLEMENTED METHODS, COMPUTER-READABLE MEDIA, AND SYSTEMS FOR TRACKING A PLURALITY OF SPERMATOZOA  
One aspect of the invention provides a computer-implemented method for tracking a plurality of spermatozoa. The method includes: identifying a coordinate for each of the plurality of spermatozoa...
9625878 Dynamic time multiplexing fabrication of holographic polymer dispersed liquid crystals for increased wavelength sensitivity  
Described herein is a new holographic polymer dispersed liquid crystal (HPDLC) medium with broadband reflective properties, and a new technique for fabrication of broadband HPDLC mediums. The new...
9623071 Modulation of hepatitis B virus CCCDNA transcription  
The present invention provides small molecule inhibitors of hepatitis B virus (HBV) covalently closed circular (ccc) DNA, which are useful as therapeutics in the management of chronic HBV. The...
US20170102332 CHEMICALLY SWITCHABLE ULTRAVIOLET PHOTOLUMINESCENCE  
The present disclosure pertains to the use of intense, narrow-linewidth surface, chemically-switchable ultraviolet photoluminescence from radiative recombination of the two-dimensional electron...
US20170100313 METHODS OF INHIBITING, PROTECTING AGAINST, OR TREATING UVR-INDUCED SKIN DAMAGE  
One aspect of the invention provides a method of inhibiting, protecting against, or treating UVR-induced skin damage in a mammal at risk of developing UVR-induced skin damage. The method includes...
9618497 All electric piezoelectric finger sensor (PEFS) for soft material stiffness measurement  
A PEFS (Piezoelectric Finger Sensor) acts as an “electronic finger” capable of accurately and non-destructively measuring both the Young's compression modulus and shear modulus of tissues with...