|
Match
|
Document |
Document Title |
|
|
US20070277249 |
Animal Selected For Lacking Heparan Sulfate-3-O-Sulfotransferase-1 and Uses Thereof
An animal selected for lacking heparan sulfate 3-O-sulfotransferase-1 activity is provided. This animal exhibits characteristics associated with myxomatous valvular disease and is useful for...
|
|
|
7296163 |
System and methods for encrypted execution of computer programs
The invention provides a method for encrypting a program for execution on a remote host computer on a network, such that correct execution by the remote host computer is ensured, and such that the...
|
|
|
7288568 |
Therapeutic compositions and methods of use
Compounds and methods useful for chemopreventative treatment of diseases such as cancer, Alzheimer's disease, Parkinson's disease, inflammatory bowel diseases, and multiple sclerosis.
|
|
|
7285270 |
Method of reducing neuropathic pain
The present invention relates to methods of treating pain. Monocyte chemoattractant protein-1 (MCP-1) antibodies or binding fragments thereof are used to prevent or reduce behavioral...
|
|
|
7270975 |
Methods for regulating bud-hypha transitions and cAMP levels in Candida albicans
The infection of a mammalian host by a microorganism can be prevented or treated through the alteration of the C. albicans homologue of the high affinity phosphodiesterase, PDE2, gene and/or the...
|
|
|
US20070213619 |
Systems And Methods For Noninvasively Monitoring Baroreflex Response And Nominal Blood Volume
Systems and methods for noninvasively monitoring baroreflex response and nominal blood volume are disclosed herein. Software and methods for evaluating morphological features of a...
|
|
|
7258995 |
Compositions and methods for affecting virulence determinants in bacteria
A novel sarR gene and sarR gene product which down regulates the expression of sarA and the resulting virulence determinants in Staphylococcus aureus is provided. Methods for modulating the...
|
|
|
7258984 |
Compositions and methods for identifying agents which regulate autolytic processes in bacteria
A nucleic acid sequence which regulates the autolytic activity of bacteria is provided. Methods for identifying and using agents which interact with the gene to inhibit bacterial growth and...
|
|
|
7241446 |
Methods for modulating angiogenesis via VEGF
Recombinant plasminogen activator inhibitor-1 (PAI-1) isoforms which lack the reactive center loop and contain the complete heparin-binding domain or lack at least a portion of the heparin-binding...
|
|
|
7238782 |
Compositions and methods for regulating RNA stability using polypyrimidine tract proteins
Compositions and methods for regulating CD154 gene expression are provided that rely on the interaction of polypyrimidine tract proteins with the 3′-untranslated region of CD154.
|
|
|
7227110 |
Prevention of ice formation by applying electric power to a liquid water layer
A first electrode is separated from a second electrode by an interelectrode space. The interelectrode space does not exceed 3 mm, and preferably does not exceed 100 μm. Liquid water fills the ...
|
|
|
7192429 |
Thermokeratoplasty systems
The present invention provides applicators for performing thermokeratoplasty. One embodiment of such applicators includes two generally tubular electrical conducting elements coaxially disposed...
|
|
|
7189891 |
Isolated ferric reductase defective polypeptides and uses thereof
Novel molecules of the multi-drug and toxin efflux (MATE) family of molecules, designated herein as mutant ferric reductase defective (FRD3) nucleic acid and protein molecules are disclosed. The...
|
|
|
7186519 |
Method for detecting intracellular cholesterol
The present invention relates to a method of detecting intracellular cholesterol. The method provides contacting a permeabilized cell with labeled Cθ complex. Methods of using this detection ...
|
|
|
US20070045282 |
Systems and methods for modifying an ice-to-object interface
A method for controlling a coefficient of friction between an object and ice includes steps of (1) pulsing power to an interface between the object and the ice to melt an interfacial layer of ice...
|
|
|
7176237 |
Tricyclic-bis-enone derivatives and methods of use thereof
Novel tricyclic-bis-enone derivatives (TBEs) as well as the process for the preparation of such TBEs are provided. Also provided are methods for prevention and/or treatment of cancer, Alzheimer's...
|
|
|
7166763 |
Mouse model of myxomatous valvular disease
An animal selected for lacking heparan sulfate 3-O-sulfotransferase-1 activity is provided. This animal exhibits characteristics associated with myxomatous valvular disease and is useful for...
|
|
|
7164100 |
High-frequency de-icing of cableways
High-frequency AC voltage with a frequency in a range of from 60 to 100 kHz supplied from a power source at 3 to 15 kV is applied to an electrical conductor within about 30 cm of a cableway. The...
|
|
|
7148328 |
Compositions and methods for regulating autolytic processes in bacteria
A nucleic acid sequence required for regulating the autolytic activity of bacteria is provided. Also provided are polypeptides encoded by the gene or mutant gene as well as vector and host cells...
|
|
|
7148210 |
Method of treating bone metastasis
The invention provides a drug combination for the treatment of diseases associated with bone metastasis. The combination provides adenosine or a derivative thereof, a bisphosphonate, and a...
|
|
|
7144710 |
Method for detecting inflammation and inflammatory conditions
Methods for detecting the inflammatory biomarkers molecule CD 163 in biological samples are provided. Also provided are methods for monitoring the course of an inflammatory process or condition in...
|
|
|
7138599 |
Plasma-based de-icing
An electrical conductor and a gas-filled layer are located at or near the surface of an object being deiced. The conductor carries an AC voltage that generates an alternating electric field in the...
|
|
|
7135182 |
Inhibition of transglutaminase-mediated microbial interaction with a mammalian host
The infection of a mammalian host by a microorganism can be prevented or treated through the administration of substrates for transglutaminases or antibodies against such substrates that inhibit...
|
|
|
US20060247531 |
System and method for spectral-encoded high-rate hemodynamic tomography
An optical tomography system has a group of lasers for generating light of multiple distinct wavelengths within a first wavelength band. Light from these lasers is directed into mammalian tissue at...
|
|
|
7129349 |
Methods of synthesizing 3-amino-1,2,4-benzotriazines
An improved method of producing 3-amino-1,2,4-benzotriazines using nitrobenzene or a derivative thereof, a guanidine salt and a base as reactants is provided. The method is carried out at a...
|
|
|
US20060222649 |
Methods for inducing antigen-specific T cell tolerance
Methods for inducing antigen-specific T cell tolerance are disclosed. The methods involve contacting a T cell with: 1) a cell which presents antigen to the T cell, wherein a ligand on the cell...
|
|
|
7109294 |
Bacterial glycosyltransferase polypeptides involved in antibiotic resistance
Disclosed are various genes encoding proteins that are shown to play a role, direct or indirect, in microbial resistance of an organism in a biofilm and homologs thereof. Also disclosed are methods...
|
|
|
US20060195157 |
Apparatus and method for modulating neurochemical levels in the brain
The present invention provides a method for modulating or regulating levels of a neurochemical in an individual using deep brain stimulation. More particularly, the invention relates to a method of...
|
|
|
7092853 |
Environmental noise monitoring system
A continuous environmental noise level recording and analysis system is provided. The system is capable of sampling, processing and storing Equivalent Sound Level values over a period of about two...
|
|
|
7087876 |
High-frequency melting of interfacial ice
An alternating electric field is applied at an ice interface to generate a resistive AC current having a frequency greater than 1000 Hz in interfacial ice. Typically, a first electrode and a second...
|
|
|
US20060173509 |
Deep brain stimulator
The present invention relates to a method for the detection and ablation of aberrant thalamic oscillations leading to tremor and/or seizure. The invention provides a high frequency stimulator...
|
|
|
7049086 |
High-throughput screening assay for cholesterol inhibitors and inhibitors identified thereby
The present invention provides a high-throughput screening assay to identify test agents as cholesterol inhibitors via mutant NCP1 mammalian cells. Also provided are cholesterol inhibiting agents...
|
|
|
7049075 |
Deoxyribonuclease IIβ proteins and cDNAs
The present invention provides cDNAs encoding deoxyribonuclease IIβ and isolated, purified deoxyribonuclease IIβ proteins. Antibodies against this protein and antisense agents targeted to a cDNA o...
|
|
|
7034257 |
Methods for modifying friction between an object and ice or snow
A method modifies friction between an object and ice or snow. The method utilizes a heating element to apply a pulse of thermal energy to an interface between the object and the ice or snow; the...
|
|
|
7033756 |
Methods of diagnosing, prognosticating and treating matrix metalloproteinase-1 related diseases via a matrix metalloproteinase-1 single nucleotide polymorphism
Methods and kits for diagnosing and prognosticating matrix metalloproteinase-1 related disease by detecting a single nucleotide polymorphism in the promoter of the gene are provided. Also provided...
|
|
|
7022487 |
Compositions and methods for regulating RNA stability using polypyrimidine tract proteins
Compositions and methods for regulating CD154 gene expression are provided that rely on the interaction of polypyrimidine tract proteins with the 3′-untranslated region of CD154.
|
|
|
7012148 |
Compositions and methods for thionation during chemical synthesis reactions
Compositions and methods for using these compositions to produce high yields of thionated compounds are provided.
|
|
|
6996241 |
Tuned feedforward LMS filter with feedback control
A method to automatically and adaptively tune a leaky, normalized least-mean-square (LNLMS) algorithm so as to maximize the stability and noise reduction performance in feedforward adaptive noise...
|
|
|
US20060012367 |
Imaging by magnetic resonance adsorption, elastography and tomography
A microwave imaging system provides superior breast imaging resolution by combining MR microwave absorption and MR-compatible microwave tomography calculations. These techniques may also be...
|
|
|
US20060008460 |
Monoclonal antibody MR1 and uses thereof
The present invention relates to a counter-receptor, termed CD40CR, for the CD40 B-cell antigen, and to soluble ligands for this receptor, including fusion molecules comprising at least a portion...
|
|
|
US20050288363 |
Therapeutic compositions and methods of use
Compounds and methods useful for chemopreventative treatment of diseases such as cancer, Alzheimer's disease, Parkinson's disease, inflammatory bowel diseases, and multiple sclerosis.
|
|
|
6943014 |
Deoxyribonuclease IIβ proteins and CDNAs
The present invention provides cDNAs encoding deoxyribonuclease IIβ and isolated, purified deoxyribonuclease IIβ proteins. Antibodies against this protein and antisense agents targeted to a cDNA o...
|
|
|
6929913 |
Compositions and methods for regulating autolytic processes in bacteria
A nucleic acid sequence required for regulating the autolytic activity of bacteria is provided. Also provided are polypeptides encoded by the gene or mutant gene as well as vector and host cells...
|
|
|
6927059 |
Compositions and methods for identifying agents which regulate autolytic processes in bacteria
A nucleic acid sequence which regulates the autolytic activity of bacteria is provided. Methods for identifying and using agents which interact with the gene to inhibit bacterial growth and...
|
|
|
US20050163780 |
Method for prolonged suppression of humoral immune response to a thymus-dependent antigen
Methods of suppressing a humoral immune response to a thymus-dependent (TD) antigen are disclosed. The methods involve administering to a subject a TD antigen with an antagonist of a molecule which...
|
|
|
US20050152897 |
Methods for inducing T cell tolerance to a tissue or organ graft
Methods for inducing T cell tolerance to a tissue or organ graft in a transplant recipeint are disclosed. The methods involve administering to a subject: 1) an allogeneic or xenogeneic cell which...
|
|
|
6887677 |
Compounds and methods for identifying compounds which inhibit a new class of aspartyl proteases
Compounds and methods for designing and identifying compounds which inhibit TFPP-like aspartyl protease enzymes by targeting the aspartic acid residues of the active site or mimicking peptides...
|
|
|
6870139 |
Systems and methods for modifying an ice-to-object interface
Systems and methods for thermally modifying an ice-to-object interface. One system includes a power supply configured to generate a magnitude of power. The magnitude of the power is sufficient to...
|
|
|
6847024 |
Prevention of ice formation by applying electric power to a liquid water layer
A first electrode is separated from a second electrode by an interelectrode space. The interelectrode space does not exceed 3 mm, and preferably does not exceed 100 μm. Liquid water fills the ...
|
|
|
6832742 |
System and method for an electrical de-icing coating
A system for modifying ice adhesion strength of ice adhered to an object comprises a composite coating containing wire electrodes covering the surface to be protected. In one embodiment, a...
|