Patents and Patent Applications from Cornell Research Foundation Inc


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9771608 Fagopyritol synthase genes and uses thereof  
The present invention relates to an isolated DNA molecule encoding a fagopyritol synthase. A method for producing a fagopyritol, an insulin mediator, an insulin mediator analog, an insulin...
9765377 Fagopyritol synthase genes and uses thereof  
The present invention relates to an isolated DNA molecule encoding a fagopyritol synthase. A method for producing a fagopyritol, an insulin mediator, an insulin mediator analogue, an insulin...
9758804 Fagopyritol synthase genes and uses thereof  
The present invention relates to an isolated DNA molecule encoding a fagopyritol synthase. A method for producing a fagopyritol, an insulin mediator, an insulin mediator analogue, an insulin...
9725759 Method of designing addressable array suitable for detection of nucleic acid sequence differences using ligase detection reaction  
The present invention is directed to a method of designing a plurality of capture oligonucleotide probes for use on a support to which complementary oligonucleotide probes will hybridize with...
9699975 Tomato plants that exhibit resistance to Botrytis cinerea  
The present invention relates to tomato plants that exhibit resistance to Botrytis cinerea and methods for developing new inbreds, hybrid, apomictic and genetically engineered tomato plants that...
9683077 Copolymerization of propylene oxide and carbon dioxide without production of propylene carbonate  
Copolymers of propylene oxide and carbon dioxide and homopolymers of propylene oxide are made using two dimensional double metal cyanide complexes having the formula Co[M(CN)4] or hydrated or...
US20170159015 MYELINATION OF CONGENITALLY DYSMYELINATED FOREBRAINS USING OLIGODENDROCYTE PROGENITOR CELLS  
One form of the present invention is directed to a method of remyelinating demyelinated axons by treating the demyelinated axons with oligodendrocyte progenitor cells under conditions which permit...
9649295 Chemical inhibitors of soluble adenylyl cyclase (sAC)  
The present invention relates to a method of treating a disorder mediated by soluble adenylyl cyclase in a subject. The method involves administering to a subject an effective amount of a compound...
US20170119787 MODULATING THE PRODUCTION OF NEURONS AND/OR OLIGODENDROCYTES FROM WHITE MATTER PROGENITOR CELLS  
The present invention relates to a method of modulating production of neurons and/or oligodendrocytes from neural progenitor cells of human white matter and to a method of treating a subject for a...
RE46379 Functional immunohistochemical cell cycle analysis as a prognostic indicator for cancer  
The present invention relates to a method of determining the presence of a retinoblastoma protein (Rb)-mediated cancerous or pre-cancerous condition in a sample of fixed cells that involves...
9623069 Methods for reducing oxidative damage  
The invention provides a method for reducing oxidative damage in a mammal, a removed organ, or a cell in need thereof. The method comprises administering an effective amount of an aromatic...
US20170088894 Methods of Predicting Acute Rejection Outcomes  
A method for assessing risk of losing a transplanted organ by a patient having an episode of acute rejection of the transplanted organ is described. The method includes obtaining from the patient...
9567353 Sol-gel precursors and products thereof  
The present invention provides a generalizable single-source sol-gel precursor capable of introducing a wide range of functionalities to metal oxides such as silica. The sol-gel precursor...
US20170037114 PROTEINS WITH REPETITIVE BACTERIAL-IG-LIKE (BIG) DOMAINS PRESENT IN LEPTOSPIRA SPECIES  
The invention relates to three isolated DNA molecules that encode for proteins, BigL1, BigL2 and BigL3, in the Leptospira sp bacterium which have repetitive Bacterial-Ig-like (Big) domains and...
US20170035899 METHOD AND CARRIER COMPLEXES FOR DELIVERING MOLECULES TO CELLS  
The invention relates to carrier complexes and methods for delivering molecules to cells. The carrier complexes comprises a molecule and an aromatic cationic peptide in accordance with the...
US20170014529 Method of Treating or Retarding the Development of Blindness  
A method for treating an ocular disorder characterized by the defect or absence of a normal gene in the ocular cells of a human or animal subject involves administering to the subject by...
9539425 Systems and methods for treating medical conditions by stimulation of medial thalamic region  
A system for treating medical conditions by neuromodulation of one or more target sites in the nervous system. In certain embodiments, at least one of the target sites is the medial thalamic...
US20160376623 FAGOPYRITOL SYNTHASE GENES AND USES THEREOF  
The present invention relates to an isolated DNA molecule encoding a fagopyritol synthase. A method for producing a fagopyritol, an insulin mediator, an insulin mediator analogue, an insulin...
US20160376573 FAGOPYRITOL SYNTHASE GENES AND USES THEREOF  
The present invention relates to an isolated DNA molecule encoding a fagopyritol synthase. A method for producing a fagopyritol, an insulin mediator, an insulin mediator analogue, an insulin...
US20160376572 FAGOPYRITOL SYNTHASE GENES AND USES THEREOF  
The present invention relates to an isolated DNA molecule encoding a fagopyritol synthase. A method for producing a fagopyritol, an insulin mediator, an insulin mediator analogue, an insulin...
US20160376571 FAGOPYRITOL SYNTHASE GENES AND USES THEREOF  
The present invention relates to an isolated DNA molecule encoding a fagopyritol synthase. A method for producing a fagopyritol, an insulin mediator, an insulin mediator analogue, an insulin...
9521955 Subdural electro-optical sensor  
A subdural electro-optical sensor system may include a substrate to which is attached an array of electrodes, light emitters, and light detectors. The sensor system may be sufficiently thin,...
9512434 Glycosylated protein expression in prokaryotes  
The present invention relates to a prokaryotic host cell comprising eukaryotic glycosyltransferase activity, where the eukaryotic glycosyltransferase activity is eukaryotic dolichyl-linked...
9505809 Proteins with repetitive bacterial-IG-like (BIG) domains present in Leptospira species  
The invention relates to three isolated DNA molecules that encode for proteins, BigL1, BigL2 and BigL3, in the Leptospira sp bacterium which have repetitive Bacterial-Ig-like (Big) domains and...
US20160319334 DETECTION OF NUCLEIC ACID SEQUENCE DIFFERENCES USING THE LIGASE DETECTION REACTION WITH ADDRESSABLE ARRAYS  
The present invention describes a method for identifying one or more of a plurality of sequences differing by one or more single base changes, insertions, deletions, or translocations in a...
US20160317604 METHODS FOR REDUCING OXIDATIVE DAMAGE  
The invention provides a method for reducing oxidative damage in a mammal, a removed organ, or a cell in need thereof. The method comprises administering an effective amount of an aromatic...
US20160264937 MYELINATION OF CONGENITALLY DYSMYELINATED FOREBRAINS USING OLIGODENDROCYTE PROGENITOR CELLS  
One form of the present invention is directed to a method of remyelinating demyelinated axons by treating the demyelinated axons with oligodendrocyte progenitor cells under conditions which permit...
US20160263246 Method of Treating or Retarding the Development of Blindness  
A method for treating an ocular disorder characterized by the defect or absence of a normal gene in the ocular cells of a human or animal subject involves administering to the subject by...
9433688 Method of treating or retarding the development of blindness  
A method for treating an ocular disorder characterized by the defect or absence of a normal gene in the ocular cells of a human or animal subject involves administering to the subject by...
9417166 System and method for increased cooling rates in rapid cooling of small biological samples  
A method and devices for rapid cooling of small biological samples by plunging them in a cryogenic liquid, such as liquid nitrogen, or contacting them with a cryogenic metal surface, reduce or...
US20160222069 PROTEINS WITH REPETITIVE BACTERIAL-IG-LIKE (BIG) DOMAINS PRESENT IN LEPTOSPIRA SPECIES  
The invention relates to three isolated DNA molecules that encode for proteins, BigL1, BigL2 and BigL3, in the Leptospira sp bacterium which have repetitive Bacterial-Ig-like (Big) domains and...
US20160215329 METHOD OF DESIGNING ADDRESSABLE ARRAY SUITABLE FOR DETECTION OF NUCLEIC ACID SEQUENCE DIFFERENCES USING LIGASE DETECTION REACTION  
The present invention is directed to a method of designing a plurality of capture oligonucleotide probes for use on a support to which complementary oligonucleotide probes will hybridize with...
9394344 Compositions and methods for the display of proteins on the surface of bacteria and their derived vesicles and uses thereof  
The present invention relates to compositions and methods for displaying proteins and polypeptides on the surface of cells and cellular vesicles. Methods and compositions for drug and vaccine...
9376668 Fagopyritol synthase genes and uses thereof  
The present invention relates to an isolated DNA molecule encoding a fagopyritol synthase. A method for producing a fagopyritol, an insulin mediator, an insulin mediator analogue, an insulin...
9375473 Method to treat autoimmune demyelinating diseases and other autoimmune or inflammatory diseases  
The invention relates to methods of preventing or inhibiting the onset and/or treating autoimmune demyelinating neuropathy and other autoimmune or inflammatory diseases involving macrophage...
9371513 Myelination of congenitally dysmyelinated forebrains using oligodendrocyte progenitor cells  
One form of the present invention is directed to a method of remyelinating demyelinated axons by treating the demyelinated axons with oligodendrocyte progenitor cells under conditions which permit...
9346858 Proteins with repetitive Bacterial-Ig-like (Big) domains present in Leptospira species  
The invention relates to three isolated DNA molecules that encode for proteins, BigL1, BigL2 and BigL3, in the Leptospira sp bacterium which have repetitive Bacterial-Ig-like (Big) domains and...
9345758 Materials and methods for respiratory disease control in canines  
The subject invention pertains to isolated influenza virus that is capable of infecting canids and causing respiratory disease in the canid. The subject invention also pertains to compositions and...
9345694 Compounds for enhancing arginase activity and methods of using same  
The present invention relates to a method for enhancing arginase activity in a damaged or injured cell. In other aspects, the invention provides a method for treating a disorder that can be...
9340834 Method of designing addressable array suitable for detection of nucleic acid sequence differences using ligase detection reaction  
The present invention is directed to a method of designing a plurality of capture oligonucleotide probes for use on a support to which complementary oligonucleotide probes will hybridize with...
9335331 Multiplexed biomarkers for monitoring the Alzheimer's disease state of a subject  
The present invention relates to a method for diagnosing a subject's Alzheimer's disease state. The method involves providing a database containing information relating to protein expression...
9315586 Method and carrier complexes for delivering molecules to cells  
The invention relates to carrier complexes and methods for delivering molecules to cells. The carrier complexes comprises a molecule and an aromatic cationic peptide in accordance with the...
US20160095959 MODULAR FABRICATION SYSTEMS AND METHODS  
The present invention relates to an article fabrication system having a plurality of material deposition tools containing one or more materials useful in fabricating the article, and a material...
9273276 Devices and methods for pharmacokinetic-based cell culture system  
A cell culture method using an in vitro microscale cell culture device having a first microscale chamber containing cells attached to an inner surface of the chamber and cell culture medium in...
9242031 Modular fabrication systems and methods  
The present invention relates to an article fabrication system having a plurality of material deposition tools containing one or more materials useful in fabricating the article, and a material...
9234241 Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays  
The present invention describes a method for identifying one or more of a plurality of sequences differing by one or more single base changes, insertions, deletions, or translocations in a...
9233106 Inhibition of beta-amyloid peptide aggregation  
The present invention relates to methods of using cocaine-binding-site ligands and cocaine-binding-site RNA aptamers to treat or prevent Alzheimer's Disease and to reduce or prevent aggregation of...
US20150359838 METHODS FOR PREVENTING OR TREATING MITOCHONDRIAL PERMEABILITY TRANSITION  
The invention provides a method of reducing or preventing mitochondrial permeability transitioning. The method comprises administering an effective amount of an aromatic-cationic peptide having at...
9206477 Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays  
The present invention describes a method for identifying one or more of a plurality of sequences differing by one or more single base changes, insertions, deletions, or translocations in a...
US20150329599 PROTEINS WITH REPETITIVE BACTERIAL-IG-LIKE (BIG) DOMAINS PRESENT IN LEPTOSPIRA SPECIES  
The invention relates to three isolated DNA molecules that encode for proteins, BigL1, BigL2 and BigL3, in the Leptospira sp bacterium which have repetitive Bacterial-Ig-like (Big) domains and...