Patents and Patent Applications from Cornell Research Foundation Inc


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8103068 Methods and systems for reconstruction of objects  
Methods and systems for reconstructing an object from observations of interaction of the object with a physical system.
8095480 System and method to enable training a machine learning network in the presence of weak or absent training exemplars  
Described is a system and method for training a machine learning network. The method comprises initializing at least one of nodes in a machine learning network and connections between the nodes to...
8094351 Fibrous micro-composite material  
Fibrous micro-composite materials are formed from micro fibers. The fibrous micro-composite materials are utilized as the basis for a new class of MEMS. In addition to simple fiber composites and...
8093351 Copolymerization of propylene oxide and carbon dioxide and homopolymerization of propylene oxide  
Copolymers of propylene oxide and carbon dioxide and homopolymers of propylene oxide are made using two dimensional double metal cyanide complexes having the formula Co[M(CN)4] or hydrated or...
8088382 Methods of inhibiting transendothelial migration of neutrophils and monocytes with anti-CD99L2 antibodies  
The present invention provides methods and compositions for modulating transendothelial migration (TEM) of leukocytes. In particular, inhibition of TEM can provide a potent therapeutic approach to...
8084254 Human blood brain barrier model  
The present invention relates to an immortalized human brain endothelial cell line that is useful as an in vitro model of the blood brain barrier.
8084001 Photoluminescent silica-based sensors and methods of use  
Sensor particles comprise a silica-based core and at least one photoluminescent dye. The silica-based core may comprise a plurality of pores and the at least one photoluminescent dye may comprise a...
US20110311586 Materials and methods for respiratory disease control in canines  
The subject invention pertains to isolated influenza virus that is capable of infecting canids and causing respiratory disease in the canid. The subject invention also pertains to compositions and...
US20110311570 PROTEINS WITH REPETITIVE BACTERIAL-IG-LIKE (BIG) DOMAINS PRESENT IN LEPTOSPIRA SPECIES  
The invention relates to three isolated DNA molecules that encode for proteins, BigL1, BigL2 and BigL3, in the Leptospira sp bacterium which have repetitive Bacterial-Ig-like (Big) domains and...
8072117 Thermal-mechanical signal processing  
A source signal is converted into a time-variant temperature field with transduction into mechanical motion. In one embodiment, the conversion of a source signal into the time-variant temperature...
8063556 Cascaded light emitting devices based on mixed conductor electroluminescence  
A cascaded light emitting device. The cascaded light emitting device includes: a base electrode formed of a base electrode material and electrically coupled to a base voltage lead; a top electrode...
8062919 Monolithic silicon-based photonic receiver  
An integrated circuit, and method for manufacturing the integrated circuit, where the integrated circuit can include a phototransistor comprising a base having a SiGe base layer of a predetermined...
8053585 Protecting group for carboxylic acids that can be photolyzed by visible light  
The present invention relates to a photolabile compound including a coumarin family caging group covalently bound to an organic moiety containing a carboxyl group, an amino group, a sulfhydryl...
8050481 Method and apparatus for small pulmonary nodule computer aided diagnosis from computed tomography scans  
The present invention is a multi-stage detection algorithm using a successive nodule candidate refinement approach. The detection algorithm involves four major steps. First, a lung region is...
8049580 MEMS controlled oscillator  
An array of micromechanical oscillators have different resonant frequencies based on their geometries. In one embodiment, a micromechanical oscillator has a resonant frequency defined by an...
8045770 System and method for three-dimensional image rendering and analysis  
The present invention relates to methods and systems for conducting three-dimensional image analysis and diagnosis and possible treatment relating thereto. The invention includes methods of...
8043803 Slitrks as markers for stem and progenitor cells and methods of use thereof  
The present invention relates to slitrk proteins as markers of stem and progenitor cells, including embryonic stem cells and hematopoietic stem and progenitor cells, and also as a marker of...
8039655 Production of isotactic and regiorandom polypropylene based polymer and block copolymers  
One step ortho-alkylation of anilines with styrenes to give chiral anilines is obtained using a strong acid catalyst, e.g. CF3SO3H. Condensation of the product to give ligand and metallation gives...
US20110250220 MODIFIED GP140 ENVELOPE POLYPEPTIDES OF HIV-1 ISOLATES, COMPOSITIONS, STABILIZED TRIMERIC COMPLEXES, AND USES THEREOF  
This invention provides a modified gp140 envelope polypeptide of an HIV-1 isolate comprising a gp120 polypeptide portion comprising consecutive amino acids and a gp41 ectodomain polypeptide portion...
8034347 Method for inhibiting apoptosis through the p75 neurotrophin receptor  
The present invention provides an isolated protein comprising a pro-domain of a proneurotrophin, methods for producing the protein, and pharmaceutical compositions containing the isolated protein....
8030449 Pressure cryocooling protein crystals  
Preparation of cryocooled protein crystal is provided by use of helium pressurizing and cryocooling to obtain cryocooled protein crystal allowing collection of high resolution data and by heavier...
8030061 Devices and methods for pharmacokinetic-based cell culture system  
Devices, in vitro cell cultures, systems, and methods are provided for microscale cell culture analogous (CCA) device.
8026512 Mobility engineered electroluminescent devices  
An electroluminescent (EL) device, including a semiconductor structure, a first electrode, and a second electrode. The semiconductor structure includes: a first higher mobility semiconductor layer...
8026317 Isotactic specific catalyst for direct production of highly isotactic poly (propylene oxide) or highly isotactic poly (butylene oxide)  
(Salph or methoxy salph) Co (initiating ligand) catalyze homopolymerizing rac-PO to produce pure highly isotactic PPO and rac-1-butylene oxide to produce pure isotactic poly(butylene oxide). A...
8021673 Proteins with repetitive Bacterial-Ig-like (Big) domains present in Leptospira species  
The invention relates to three isolated DNA molecules that encode for proteins, BigL1, BigL2 and BigL3, in the Leptospira sp bacterium which have repetitive Bacterial-Ig-like (Big) domains and...
US20110195854 DETECTING AND MONITORING INFLAMMATORY NEUROPATHY  
The invention relates to detection and/or monitoring of inflammatory neuropathy using markers that specifically indicate the presence of inflammatory neuropathy, for example, allograft inflammatory...
7993938 Highly doped III-nitride semiconductors  
A method of forming a highly doped layer of AlGaN, is practiced by first removing contaminants from a MBE machine. Wafers are then outgassed in the machine at very low pressures. A nitride is then...
7989586 Multiblock copolymers having improved mechanical properties  
Replacement of the amorphous peptide domain of a structural biopolymer, such as silk from silkworms or spiders, with a nonpeptide segment while maintaining the β-sheet forming crystalline segments ...
US20110184043 INHIBITION OF ANGIOGENESIS  
The present invention relates to the microRNA miR-126 and to inhibitors of miR-126 that regulate angiogenesis. The present invention provides compositions and methods for the inhibition of miR-126...
US20110182924 PROTEINS WITH REPETITIVE BACTERIAL-IG-LIKE (BIG) DOMAINS PRESENT IN LEPTOSPIRA SPECIES  
The invention relates to three isolated DNA molecules that encode for proteins, BigL1, BigL2 and BigL3, in the Leptospira sp bacterium which have repetitive Bacterial-Ig-like (Big) domains and...
7986227 System and method for position matching of a patient for medical imaging  
A system for position matching of a patient for medical imaging includes a set of RFID tags configured to locate a patient position. A set of RFID interrogators are located to receive RFID position...
US20110177975 DETECTION OF NUCLEIC ACID SEQUENCE DIFFERENCES USING THE LIGASE DETECTION REACTION WITH ADDRESSABLE ARRAYS  
The present invention describes a method for identifying one or more of a plurality of sequences differing by one or more single base changes, insertions, deletions, or translocations in a...
US20110177343 POLYMERS AND POLYMER COATINGS  
The invention provides polymers, methods of preparing polymers, and compositions that include polymers, wherein said polymers include a plurality of two-carbon repeating units in a polymer chain,...
US20110177079 Cancer-testis antigens  
The invention relates to cancer-testis antigens and the nucleic acid molecules that encode them. The invention further relates to the use of the nucleic acid molecules, polypeptides and fragments...
US20110171194 METHODS AND COMPOSITIONS FOR INHIBITING ABAD/ABeta PROTEIN INTERACTION  
This invention provides methods, compositions and articles of manufacture for inhibiting binding between Aβ protein and ABAD in cells. Uses of this invention include, for example, treating ...
US20110169193 MODULAR FABRICATION SYSTEMS AND METHODS  
The present invention relates to an article fabrication system having a plurality of material deposition tools containing one or more materials useful in fabricating the article, and a material...
7977366 Treating an inflammatory disorder or inhibiting respiratory burst in adherent neutrophils with chemical inhibitors of neutrophil activation  
The present invention relates to a method of treating an inflammatory disorder in a subject with an effective amount of compound having the general formula (I) as described in the present...
US20110166207 USE OF AAV INTEGRATION EFFICIENCY ELEMENT FOR MEDIATING SITE-SPECIFIC INTEGRATION OF A TRANSCRIPTION UNIT  
The invention provides an expression construct comprising a nucleic acid sequence encoding an adeno-associated virus integration efficiency element (AAV IEE), wherein the expression construct is...
US20110166074 CLN2 TREATMENT OF ALZHEIMER'S DISEASE  
A method of treating Alzheimer's Disease may include administering to a subject in need of such treatment a CLN2 therapeutic having beta-amyloid degradation activity.
7960776 Transistor with floating gate and electret  
A sensor includes a field effect transistor having a source, drain, a control gate and floating gate, wherein the floating gate has an extended portion extending away from the control gate. A...
7959929 Materials and methods for respiratory disease control in canines  
The subject invention pertains to isolated influenza virus that is capable of infecting canids and causing respiratory disease in the canid. The subject invention also pertains to compositions and...
7958790 Biaxial load cell with highly anisotropic force resolutions  
A load cell for measuring extremely low level, anisotropic biaxial loads is disclosed. The system includes at least one load cell of a specific geometry and dimension which, when mounted, provides...
US20110121819 AMPLIFIER AND ARRAY FOR MEASURING SMALL CURRENT  
An array of electrochemical detectors includes an array of electrodes that provide current responsive to oxidation events. Each electrode is coupled to a transistor, an amplifier coupled to an...
7947774 Ethylene-vinyl acetate copolymer of increased mechanical properties  
Solution blending of masterbatch of cationically functionalized polyvinyl acetate copolymer/silicate nanocomposite where the silicate is substantially exfoliated, and ethylene-vinyl acetate...
7947453 Methods for drug discovery, disease treatment, and diagnosis using metabolomics  
The small molecule profiles of cells are compared to identify small molecules which are modulated in altered states. Cellular small molecule libraries, methods of identifying tissue sources,...
7947439 Detection of bovine viral diarrhea virus in tissue samples  
The present invention relates to a method of detecting whether a target animal is Bovine Viral Diarrhea Virus (BVDV) positive or negative by determining whether a gp48 protein-specific reagent...
7947438 Detection of bovine viral diarrhea virus in hair samples  
The present invention relates to a method of detecting whether a target animal is Bovine Viral Diarrhea Virus (BVDV) positive or negative by determining whether a gp48 protein-specific reagent...
US20110118274 PROTEASOME INHIBITORS AND THEIR USE IN TREATING PATHOGEN INFECTION AND CANCER  
The present invention relates to proteasome inhibitors and their use in methods of treating a subject for a pathogen infection or cancer. The methods involve administering to the subject a compound...
7943307 Methods for analyzing nucleic acid sequences  
The present invention is directed to a method of sequencing a target nucleic acid. The method provides a complex comprising a polymerase enzyme, a target nucleic acid molecule, and a primer,...
7943305 High speed nucleic acid sequencing  
The present invention is directed to a method of sequencing a target nucleic acid molecule having a plurality of bases. In its principle, the temporal order of base additions during the...