Patents and Patent Applications from Cornell Research Foundation Inc


Match Document Document Title
US20050129734 Hydrogel entrapping therapeutic agent and stent with coating comprising this  
A hydrogel forming system which comprises a hydrophobic macromer with unsaturated group terminated ends and a hydrophilic polymer which is a polysaccharide containing hydroxy groups which are...
6905700 Hydrogel entrapping therapeutic agent and stent with coating comprising this  
A hydrogel forming system which comprises a hydrophobic macromer with unsaturated group terminated ends and a hydrophilic polymer which is a polysaccharide containing hydroxy groups which are...
6903248 DNA constructs and methods to impart resistance to at least one virus on plants  
The present invention is directed to a DNA construct comprising a first DNA molecule having a length insufficient to independently impart resistance to a virus to plants transformed with said first...
6903247 Constitutive α-Tubulin promoter from coffee plants and uses thereof  
The present invention relates to the isolation and characterization of a constitutive α-tubulin promoter from a coffee plant. The isolated promoter of the present invention is capable of inducing ...
6900575 Multiple mechanical resonator parametric device  
A resonator device utilizes two small mechanical resonators that are electrostatically coupled. A first resonator receives an input signal near its resonant frequency, and the input signal and a...
6900015 Measurement of protective genes in allograft rejection  
The invention relates to methods of evaluating transplant rejection in a host comprising determining a heightened magnitude of gene expression of genes in rejection-associated gene clusters. The...
US20050113084 Methods and systems for cooperative transmission in multi-hop ad-hoc networks  
Methods and systems that enable a cooperative form of transmission performed by a set of asynchronous transceivers operating as a distributed joint communication system. In an embodiment of the...
6896883 Biocontrol for plants with Bacillus subtilis, Pseudomonas putida, and Sporobolomyces roseus  
The present invention is directed to isolated Bacillus subtilis, Pseudomonas putida, and Sporobolomyces roseus which are useful as a biocontrol agent. These organisms are useful in a method of...
US20050106125 Use of AAV integration efficiency element for mediating site-specific integration of a transcription unit  
The invention provides an expression construct comprising a nucleic acid sequence encoding an adeno-associated virus integration efficiency element (AAV IEE), wherein the expression construct is...
6890533 Betulinol derivatives  
The present invention is directed to betulinol derivatives and betulinol-antibody conjugates having the formulae: and HO-antibody-spacer-(A2)n and, in particular, betulinol dimethyl ether. Methods...
6888170 Highly doped III-nitride semiconductors  
A method of forming a highly doped layer of AlGaN, is practiced by first removing contaminants from a MBE machine. Wafers are then outgassed in the machine at very low pressures. A nitride is then...
6884809 Method and compositions for reducing cardiac dysfunctions with a selective histamine H3 receptor agonist  
The invention provides a method for reducing cardiac dysfunctions in a human. The method comprises administration to the human of an effective amount of a selective histamine H3 Receptor agonist....
6882876 Diagnosis of normal pressure hydrocephalus by automated processing of MR images  
A method useful in diagnosing normal pressure hydrocephalus and monitoring treatment is presented. A database of mean brain diffusion constants and distribution width is created. Three-dimensional...
6878364 Animal model for flaviviridae infection  
The present invention is a woodchuck or an isolated woodchuck cell infected with bovine viral diarrhea virus. The invention can be used to identify new compounds for the treatment of flavivirus,...
6875852 DNA polymerase III holoenzyme  
The present invention is directed toward the 5 previously unknown genes, for subunits δ, δ′, χ, θ, and ψ, of the DNA polymerase III holoenzyme, and toward a unique man-made enzyme containing 5, pre...
6872569 In vitro production of haploid germ cells  
The present invention relates to a method of in vitro spermatogenesis involving Sertoli cells and diploid germ cells from a testis of a male mammal to yield differentiated haploid spermatids. The...
6872551 Rapidly cleavable sumo fusion protein expression system for difficult to express proteins  
A recombinant expression system for the expression of a poly amino acid, peptide or protein is provided. The poly amino acid of interest is expressed as a fusion protein that includes an amino acid...
US20050063953 Adenoviral vector with replication-dependent transgene expression  
The invention provides an adenoviral vector comprising (a) at least a portion of an adenoviral genome comprising a major late transcription unit containing a terminal exon, wherein the terminal...
US20050059656 Compositions and methods for protecting against mitochondria component-mediated pathology  
Compositions and methods used for preventing mitochondrial component-based diseases are disclosed herein. In particular, heterocyclic compositions and methods that are directed toward protecting...
US20050048896 Air flow monitoring and control system with reduced false alarms  
An air flow monitoring and control system with reduced false alarms includes an alarm sensor for monitoring air flow in a fume hood or the like, set to provide a warning if air flow drops below a...
6859272 Spectrometer sample generating and injecting system using a microliter nebulizer  
A system atomizes liquids into a gaseous medium for formation and injection of a sample into an analytical apparatus, such as a plasma spectrometer. The system employs a high efficiency nebulizer...
6858707 Hypersensitive response elicitor fragments which are active but do not elicit a hypersensitive response  
The present invention is directed to isolated active fragments of a hypersensitive response elicitor protein or polypeptide which fragment does not elicit a hypersensitive response in plants. Also...
6858426 Grapevine leafroll virus (type 2) proteins and their uses  
The present invention relates to isolated proteins or polypeptides of grapevine leafroll virus (type 2). The encoding DNA molecules either alone in isolated form or in an expression system, a host...
6855683 Hypersensitive response elicitor from Erwinia amylovora, its use, and encoding gene  
The present invention is directed to an isolated protein or polypeptide which elicits a hypersensitive response in plants as well as an isolated DNA molecule which encodes the hypersensitive...
US20050032171 hCG-hLH receptor and hCG-hLH receptor-hCG complex as antigens, antibodies thereto and contraceptive vaccine  
Purified hCG-hLH receptor, hCG-hLH receptor-hCG complex and combinations between their subunits as antigens, as well as antibodies thereto which are useful as a contraceptive vaccine. Antibodies to...
US20050031759 Flavorful low-fat and reduced fat cheese  
The invention provides flavorful low-fat cheeses that are readily and inexpensively made from high-fat cheeses.
6852865 Catalytic carbonylation of three and four membered heterocycles  
Epoxides, aziridines, thiiranes, oxetanes, lactones, lactams and analogous compounds are reacted with carbon monoxide in the presence of a catalytically effective amount of catalyst having the...
6852533 Purified populations of stem cells  
The invention is directed to a purified population of mammalian endothelial, muscle, or neural stem cells. The invention further provides methods for isolating such populations of cells; methods...
6852487 Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays  
The present invention describes a method for identifying one or more of a plurality of sequences differing by one or more single base changes, insertions, deletions, or translocations in a...
6841370 Site-directed mutagenesis of Escherichia coli phytase  
The present invention relates to an isolated mutant acid phosphatase/phytase with improved enzymatic properties. The mutant acid phosphatase/phytase composition is particularly useful in animal...
6839586 Use of multiphoton excitation through optical fibers for fluorescence spectroscopy in conjunction with optical biopsy needles and endoscopes  
The present invention is directed to a method of applying radiation through an optical fiber for detecting disease within a plant or animal or imaging a particular tissue of a plant or animal. In...
US20040260042 Bis (Salicylaldiminato) titanium complex catalysts, highly syndiotactic polypropylene by a chain-end control mechanism, block copolymer containing this  
Bis(salicylaldiminato)titanium complex with optionally substituted phenyl or cyclohexyl on nitrogen catalyzes highly syndiospecific polymerization of propylene. Syndiotactic polypropylene with...
6830924 Isolated nucleic acid molecule encoding cancer associated antigens, the antigens per se, and uses thereof  
The invention relates to newly identified cancer associated antigens, referred to as CT7, KOC-2 and KOC-3. The invention also relates to observations regarding known molecule KOC-1. It has been...
6830747 Biodegradable copolymers linked to segment with a plurality of functional groups  
Biocompatible biodegradable polymer or copolymer is capped at one end and has free hydroxyl at the other end. The free hydroxyl can be reacted to link a plurality of functional groups some or each...
6828113 IgM antibodies to the 70 kDa heat shock protein as a marker for cytomegalovirus infection  
The present invention provides a method for detecting the presence of cytomegalovirus (CMV) in a fetal sample by determining the presence of anti-hsp70 antibodies present in the fetal sample. The...
US20040240782 Light scattering optical resonator  
Ring or disc optical resonators are provided with random or coherent corrugation on a top surface to cause optical power to be radiated in a desired direction by light scattering. The resonators...
6825173 Preparation of fagopyritols and uses therefor  
The present invention describes isolated Fagopyritol A1, isolated Fagopyritol A3, and isolated Fagopyritol B3. Compositions which include two or more of Fagopyritol A1, Fagopyritol A2, Fagopyritol...
6824770 Adenovirus gene expression system  
The invention is directed to an adenoviral vector comprising (a) at least one insertion site for cloning a heterologous gene, and, in an orientation opposite to the direction of transcription of...
6818804 Tospovirus resistance in plants  
The nucleotide sequences for tomato spotted wilt virus (TSWV) nucleocapsid is described, and transgenic plants containing the nucleocapsid nucleotide sequence from a TSMV isolate is shown to...
6815209 Laser-induced cell lysis system  
A method of determining laser parameters for lysing cells involves exposing cells from a sub-sample of a sample to laser light. At least one parameter of the laser is varied, and damage to...
6815175 Anti-amyloid peptide antibody based diagnosis and treatment of a neurological disease or disorder  
The invention provides a method for assessing risk of a neurodegenerative disease or disorder in a subject. The method comprises comparing a level of anti-β-amyloid-42 (Aβ42) antibody in a b...
6812027 Discovery, localization, harvest, and propagation of an FGF2 and BDNF-responsive population of neural and neuronal progenitor cells in the adult human forebrain  
The present invention provides neuronal progenitor cells which have been identified in histological sections of the adult human brain. The present invention also provides methods to localize,...
US20040213334 Real-time software receiver  
A real-time software receiver that executes on a general purpose processor. The software receiver includes data acquisition and correlator modules that perform, in place of hardware correlation,...
6808735 Flavorful low-fat cheese  
The invention provides flavorful low-fat cheeses that are readily and inexpensively made from high-fat cheeses.
US20040197831 ANTI-AMYLOID PEPTIDE ANTIBODY BASED DIAGNOSIS AND TREATMENT OF A NEUROLOGICAL DISEASE OR DISORDER  
The invention provides a method for assessing risk of a neurodegenerative disease or disorder in a subject. The method comprises comparing a level of anti-amyloid peptide antibody in a biological...
US20040197333 Use of TGF-beta antagonists to inhibit tumor cell formation or progression  
The invention provides a method for reducing formation or progression of neoplasms associated with immunosuppressive therapy in a mammal, the method comprising treating the mammal with an effective...
6800435 Insect sodium channels from insecticide-susceptible and insecticide-resistant house flies  
The present invention is directed to isolated nucleic acid molecules encoding a voltage-sensitive sodium channel (VSSC) of Musca domestica, the VSSC being capable of conferring insecticide...
6797470 Detection of nucleic acid sequence differences using coupled ligase detection and polymerase chain reactions  
The present invention relates to the detection of nucleic acid sequence differences using coupled ligase detection reaction and polymerase chain reaction. One aspect of the present invention...
PP15154 Plum Tree named ‘HoneySweet’  
A new and distinct variety of plum is transgenic and is characterized by the presence of the plum pox virus coat protein gene and genes for kanamycin resistance (NPTII) and β-glucuronidase (GUS). ...
6794501 Colon cancer antigen panel  
The invention provides methods for diagnosing cancer including colon cancer, based on the identification of certain colon cancer-associated polypeptides as antigens that elicit immune responses in...