Patents and Patent Applications from Columbia University


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US20180268142 UNSUPERVISED ANOMALY-BASED MALWARE DETECTION USING HARDWARE FEATURES  
Disclosed are devices, systems, apparatus, methods, products, media and other implementations, including a method that includes obtaining current hardware performance data, including hardware...
US20180265935 VIROME CAPTURE SEQUENCING PLATFORM, METHODS OF DESIGNING AND CONSTRUCTING AND METHODS OF USING  
The present invention provides novel methods, systems, tools, and kits for the simultaneous detection, identification and/or characterization of all viruses known or suspected to infect...
US20180264306 Human Musculoskeletal Support and Training System Methods and Devices  
A Trunk Support Trainer (TruST) is a dynamic device that trains subjects to improve strength and coordination of the upper body, while seated, and facilitates the trunk to safely move beyond the...
RE47045 Compositions and methods for treating macular degeneration  
Methods of retarding formation of a lipofuscin pigment in the retina and of treating or ameliorating the effects of a disease characterized by an accumulation of a lipofuscin pigment in a retina...
US20180258217 QUANTITATIVE INTRAMOLECULAR FISSION IN OLIGOACENES, MATERIALS, AND METHODS OF USE THEREOF  
The present invention provides soluble, stable singlet fission (SF) compounds, compositions, materials, methods of their use, and methods for their preparation that provide efficient...
US20180256816 Systems, Methods, and Devices for In Vivo Delivery Using Remote Actuation of Implantable Hydrogel MEMS Devices  
MicroElectroMechanical System (MEMS) devices can be fabricated completely of hydrogel materials. Such hydrogels can include polyethylene glycol with diacrylate functional groups (e.g., PEGDA),...
US20180256642 BIOMATERIALS DERIVED FROM TISSUE EXTRACELLULAR MATRIX  
Region-specific extracellular matrix (ECM) biomaterials are provided. Such materials include acellular scaffolds, sponges, solutions, and hydrogels suitable for stem cell culture.
10072016 Substituted 4-phenylpiperidines, their preparation and use  
The present invention provides a compound having the structure: whereinR1, R2, R3, R4, and R5 are each independently H, halogen, CF3 or C1-C4 alkyl, wherein two or more of R1, R2, R3, R4, or R5...
10071262 Apparatus, method, and system for selectively effecting and/or killing bacteria  
Certain exemplary embodiments of the present disclosure can provide an apparatus and method for generating at least one radiation can be provided. The exemplary apparatus and/or method can...
10070643 Reperfusion with omega-3 glycerides promotes donor organ protection for transplantation  
It has been discovered that isolated organs and tissues perfused/reperfused in perfusion buffer to which omega-3 glyceride oil had been added retain higher levels of function than if...
10069854 Methods, systems and media for evaluating layered computer security products  
Methods, systems and media for evaluating layered computer security products are provided. In some embodiments, the method comprises: (a) identifying portions of attack data associated with an...
US20180247386 SYSTEMS AND METHODS FOR STEGANOGRAPHY BASED ON TEXT FONTS  
Disclosed are methods, systems, devices, apparatus, media, and other implementations, including a method that includes obtaining input visual data comprising a sequence of symbols, selected from a...
US20180247069 INHIBITING MEMORY DISCLOSURE ATTACKS USING DESTRUCTIVE CODE READS  
Disclosed are devices, systems, apparatus, methods, products, and other implementations, including a method that includes determining whether an operation to access a memory location containing...
US20180246096 DETECTION OF SERUM ANTI-FADA ANTIBODIES AND RELATED DIAGNOSTIC METHODS  
The present invention relates to detecting serum anti-FadA antibodies in test samples from a patient. Additionally, aspects of the present invention provide the basis for detection of serum...
US20180245182 METHODS AND SYSTEMS FOR RECOVERING PRODUCTS FROM IRON AND STEEL SLAG  
Systems and methods for processing slag produced by iron and steel making processes are disclosed. The slag is treated produce a series of valued industrial products, such as metal oxides, metal...
US20180244603 HISTONE ACETYLTRANSFERASE MODULATORS AND USES THEREOF  
The invention provides compounds and compositions comprising compounds that modulate histone acyl transferase (HAT). The invention further provides methods for treating neurodegenerative...
10063576 Detecting network anomalies by probabilistic modeling of argument strings with markov chains  
Systems, methods, and media for detecting network anomalies are provided. In some embodiments, a training dataset of communication protocol messages having argument strings is received. The...
10063574 Apparatus method and medium for tracing the origin of network transmissions using N-gram distribution of data  
A method, apparatus, and medium are provided for tracing the origin of network transmissions. Connection records are maintained at computer system for storing source and destination addresses. The...
10063197 Circuits for power-combined power amplifier arrays  
Circuits for power-combined power amplifier array are provided, the circuits comprising: an input splitter coupled to an input that provides a plurality of outputs; a plurality of power amplifier...
10061753 Systems and methods for content extraction from a mark-up language text accessible at an internet domain  
Systems and methods are presented for content extraction from markup language text. The content extraction process may parse markup language text into a hierarchical data model and then apply one...
10061111 Systems and methods for three dimensional imaging  
Methods, devices and systems for up to three-dimensional scanning of target regions at high magnification are disclosed.
10059934 Leucine beta roll domains and uses thereof  
In one aspect, the invention relates to a peptide that forms a calcium-dependent hydrogel using a rationally engineered beta roll peptide. In the absence of calcium, the peptide is intrinsically...
10058837 Systems, methods, and devices for production of gas-filled microbubbles  
Gas-filled microbubbles can be synthesized using a continuous flow chamber and a sonicator. The resulting microbubble solution can be size-sorted for a particular application, such as injection...
10058276 MEMS affinity sensor for continuous monitoring of analytes  
Techniques for monitoring a target analyte in a sample using a polymer capable of binding to the target analyte are disclosed. An implantable monitor useful for the disclosed techniques includes a...
US20180237751 METHOD FOR GENERATING BETA CELLS  
The invention is directed to methods for generating pancreatic progenitor cells, insulin producing cells or endoderm cells using embryonic stem cells and induced pluripotent stem cells. The...
US20180237451 ALDOSE REDUCTASE INHIBITORS AND METHODS OF USE THEREOF  
The present disclosure relates to novel compounds and pharmaceutical compositions thereof, and methods for promoting healthy aging of skin, the treatment of skin disorders, the treatment of...
US20180237391 OCTAHYDROCYCLOPENTAPYRROLES, THEIR PREPARATION AND USE  
The present invention provides Octahydrocyclopentapyrrole compounds having the structure: (structurally represented) wherein psi is absent or present, and when present is a bond; R1, R2, R3, R4,...
10055587 Implementations to facilitate hardware trust and security  
Disclosed are devices, systems, apparatus, methods, products, media and other implementations, including a method that includes triggering a beacon circuit combined with a hardware-based...
10055251 Methods, systems, and media for injecting code into embedded devices  
Mechanisms for injecting code into embedded devices are provided. In some embodiments, once the code is injected into the embedded device, the injected code can analyze and modify the code of the...
10052364 Osteocalcin as a treatment for cognitive disorders  
Methods and compositions for treating or preventing cognitive disorders in mammals, preferably humans, are provided. The methods generally involve modulation of the OST-PTP signaling pathway or...
10052324 Aldose reductase inhibitors and uses thereof  
The present invention relates to novel compounds and pharmaceutical compositions thereof, and methods for promoting healthy aging of skin, the treatment of skin disorders, the treatment of...
US20180232508 LEARNING ENGINES FOR AUTHENTICATION AND AUTONOMOUS APPLICATIONS  
Disclosed are methods, systems, devices, apparatus, media, and other implementations, including a method that includes obtaining user-related data from a plurality of input sources, deriving...
US20180228422 METHODS AND SYSTEMS FOR EVALUATING AGE-RELATED MEMORY LOSS  
Methods and systems for measuring brain function of a person are disclosed. In some embodiments, the methods include the following: providing a database including digital image files that define...
US20180224875 DIGITAL LOW DROP-OUT REGULATOR  
A regulator includes: an ADC for detecting a change in an output voltage and outputting an error code; a control signal generation unit for generating a proportional control signal, integral...
US20180222919 N-ALKYL-2-PHENOXYETHANAMINES, THEIR PREPARATION AND USE  
The present invention provides a compound having the structure: (structurally represented) wherein R1, R2, R3, R4, and R5 are each independently H, halogen, CF3 or C1-C4 alkyl; R6 is alkyl; A is...
US20180221201 Laser Induced Collagen Crosslinking in Tissue  
The presently disclosed subject matter provides techniques for inducing collagen cross-linking in human tissue, such as cartilage or cornea, without using a photosensitizer (e.g., riboflavin), by...
10041689 Wireless automatic temperature control of radiator heating  
An insulated heating-unit cover having an opening to permit air to circulate around the heating-source when a vent disposed at the top of the cover is opened, allowing heat into a space. The cover...
10039277 Tissue preservation system  
The present invention provides a method and apparatus for tissue, such as an allograft, storage and preservation for extended periods of time at room temperature in a sterile tissue culture...
US20180219567 CIRCUITS AND METHODS FOR DETECTING INTERFERERS  
Mechanisms for interferer detection can detect interferers by detecting elevated signal amplitudes in one or more of a plurality of bins (or bands) in a frequency range between a maximum frequency...
US20180215847 CYCLOPROPENIUM POLYMERS AND METHODS FOR MAKING THE SAME  
The present invention provides, inter alia, a process for incorporating a cyclopropenium ion into a polymeric system. Processes for making cross-linked polymers, linear polymers, and dendritic...
US20180215748 EPOTHILONE B AND DICTYOSTATIN ANALOGS, THEIR PREPARATION AND USE  
A compound having the structure:
US20180214024 Optical Imaging or Spectroscopy Systems and Methods  
Optical imaging or spectroscopy described can use laminar optical tomography (LOT), diffuse correlation spectroscopy (DCS), or the like. An incident beam is scanned across a target. An orthogonal...
10039033 Systems, methods, and media for implementing call handoff between networks  
Systems, methods, and media for implementing call handoff between networks are provided, in some embodiments, systems for implementing call handoff between networks are provided, the systems...
10038704 Systems and methods for correlating and distributing intrusion alert information among collaborating computer systems  
Systems and methods for correlating and distributing intrusion alert information among collaborating computer systems are provided. These systems and methods provide an alert correlator and an...
US20180208487 System for Cleansing Organisms from Water  
Techniques for depleting target organisms in water include a waterproof transducer configured for ensonifying a container of water with low intensity sound at one or more ultrasound frequencies...
US20180207269 Methods of Treating CD166-Expressing Cancer  
It has now been discovered that activated lymphocyte cell adhesion molecule (ALCAM)-also known as CD166-is the ligand of the innate immune receptor ILT3 that is expressed by DC and monocytes. It...
US20180206505 Botanical Antimicrobial Compositions  
Disclosed are compositions comprising antimicrobially effective low concentrations of benzyl alcohol, one or more essential oil and one or more botanical extract. The compositions of the...
10030269 Biomarkers, methods, and compositions for inhibiting a multi-cancer mesenchymal transition mechanism  
The present invention relates to the discovery that the modulation of particular microRNAs can be employed to inhibit a mesenchymal transition that, in certain instances, correlates with...
10028723 Systems and methods for real-time, transcranial monitoring of blood-brain barrier opening  
Systems and techniques for real-time, transcranial monitoring of safe blood-brain barrier opening include determining an approach angle for targeted blood-brain barrier opening proximate a...
US20180201642 MASSIVE PARALLEL METHOD FOR DECODING DNA AND RNA  
This invention provides methods for attaching a nucleic acid to a solid surface and for sequencing nucleic acid by detecting the identity of each nucleotide analogue after the nucleotide analogue...