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US20120028241 |
Assay System for Monitoring the Effects of Genetically Engineered Cells to Alter Function of a Synctium
This invention provides methods for determining the ability of a gene construct to alter the rhythm and contractility of a syncytial cell. Furthermore, this invention provides methods for...
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US20120027742 |
METHODS FOR TREATING ADULT RESPIRATORY DISTRESS SYNDROME
We have discovered that the activated phosphorylated form of focal adhesion kinase (hereafter “FAKp”) strengthens the microvascular endothelial cell (EC) junctions that form a barrier in pul...
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8097650 |
Method of treating a condition associated with phosphorylation of TASK-1
This invention provides methods and compositions for treating a condition associated with phosphorylation of TASK-1 in a subject comprising administering to the subject an amount of an agent...
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8097162 |
Systems and methods of microfluidic membraneless exchange using filtration of extraction outlet streams
A device, system and method for exchanging components between first and second fluids by direct contact in a microfluidic channel. The fluids flow as thin layers in the channel. One of the fluids...
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8096941 |
Insertable device and system for minimal access procedure
The present invention provides a system and single or multi-functional element device that can be inserted and temporarily placed or implanted into a structure having a lumen or hollow space, such...
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US20120008495 |
Methods And Systems For Controlling SIP Overload
Techniques for controlling Session Initiation Protocol (SIP) overload between a sending entity and a receiving entity includes receiving a message at a send buffer at the sending entity and...
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8092684 |
Systems and methods of microfluidic membraneless exchange using filtration of extraction outlet streams
A device, system and method for exchanging components between first and second fluids by direct contact in a microfluidic channel. The fluids flow as thin layers in the channel. One of the fluids...
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8088575 |
Massive parallel method for decoding DNA and RNA
This invention provides methods for attaching a nucleic acid to a solid surface and for sequencing nucleic acid by detecting the identity of each nucleotide analogue after the nucleotide analogue...
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8087784 |
Systems and methods for displaying three-dimensional images
Systems and methods for displaying three-dimensional (3D) images are described. In particular, the systems can include a display block made from a transparent material with optical elements...
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8086409 |
Method of selecting genes from continuous gene expression data based on synergistic interactions among genes
Systems and methods for selecting factors from a continuous data set of measurements are provided. The measurements include values of factors and/or outcomes. Two or more factors that are jointly...
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8084593 |
Polynucleotide encoding a TRIM-Cyp polypeptide, compositions thereof, and methods of using same
The invention provides an isolated nucleic acid encoding a TRIM—cyclophilin A fusion sequence encoding a TRIMcyp fusion protein which is active as an anti-viral agent, and in particular an a...
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8084204 |
Displacement assay for detection of small molecules
Complex of an anti-cocaine aptamer and the dye diethylthiotricarbocyanine behaves as a calorimetric sensor with attenuation in absorbance at 760 nm for cocaine in the concentration range of 2-5000...
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8083706 |
Apparatus and systems for membraneless separation of fluids
The present invention is directed to devices, systems and methods for removing undesirable materials from a sample fluid by contact with a second fluid. The sample fluid flows as a thin layer...
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US20110314367 |
System And Method For Annotating And Searching Media
A system and method for labeling and classifying multimedia data is provided that includes novel label propagation techniques and classification function characteristics. The system and method...
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US20110312904 |
COMPOUNDS, COMPOSITIONS AND METHODS FOR REDUCING TOXICITY AND TREATING OR PREVENTING DISEASES
The present invention provides compounds of Formula (I), compositions comprising an effective amount of a compound of Formula (I), optionally with chemotherapeutic drugs such as a tubulin-binding...
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US20110309370 |
SYSTEMS AND METHODS FOR THE CRYSTALLIZATION OF THIN FILMS
Crystallization of thin films using pulsed irradiation The method includes continuously irradiating a film having an x-axis and a y-axis, in a first scan in the x-direction of the film with a...
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8080281 |
Growth and applications of ultralong carbon nanotubes
Ultralong carbon nanotubes can be formed by placing a secondary chamber within a reactor chamber to restrict a flow to provide a laminar flow. Inner shells can be successively extracted from...
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US20110306840 |
CONTROLLABLE MAGNETIC SOURCE TO FIXTURE INTRACORPOREAL APPARATUS.
A first magnetic field can be produced across a tissue region using a first magnetic field source, providing a magnetic coupling force between the first magnetic field source and a first object,...
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US20110306045 |
Method for Confirming a Diagnosis of Rolandic Epilepsy
A strong association between variants in Elongator Protein Complex 4, (ELP4) (specifically single nucleotide polymorphisms, SNPs) at the 11p13 locus on chromosome 11 and the centrotemporal sharp...
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8078257 |
Complex amplitude modulation in blood flow and perfusion measurement for measuring a distribution of transit times on a voxel by voxel basis
Systems and methods for blood flow and perfusion measurement using complex amplitude modulation of MRI pulses are presented. In exemplary embodiments of the disclosed subject matter, inflowing...
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US20110301495 |
IMAGES OF LANGUAGE-SENSITIVE NEUROCIRCUITRY AS A DIAGNOSTIC FOR AUTISM
The disclosed subject matter provides on ore more imaging techniques during passive auditory stimulation to objectively provide a diagnostic indicator of ASD. These techniques include functional...
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US20110300543 |
METHODS FOR MAKING INDUCED PLURIPOTENT STEM CELLS FROM MESENCHYMAL STEM CELLS
The invention is directed to methods for making iPS cells from Mesenchymal Stem Cells (MSCs). In certain aspects the methods comprise expression of Oct4 in MSCs, thereby converting the MSCs to iPS...
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US20110300203 |
CARTILAGE REGENERATION WITHOUT CELL TRANSPLANTATION
Provided is a method of causing a cell to migrate to a scaffold. Also provided is a method of treating a mammal that has a cartilage defect. Further provided is a tissue scaffold comprising stromal...
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8074115 |
Methods, media and systems for detecting anomalous program executions
Methods, media, and systems for detecting anomalous program executions are provided. In some embodiments, methods for detecting anomalous program executions are provided, comprising: executing at...
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US20110295105 |
SYSTEMS AND METHODS FOR OPENING A TISSUE
Systems and methods for opening a tissue to a target value are disclosed herein. In an exemplary method, a region of the tissue is targeted for opening, a size range of microbubbles corresponding...
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US20110294874 |
DIAGNOSIS AND THERAPY OF ORGAN DYSFUNCTION USING SPHINGANINE-1-PHOSPHATE
The invention relates to the treatment and diagnosis of organ dysfunction caused by ischemia reperfusion injury. In particular, the invention relates to sphinganine-1-phosphate, a sphingolipid...
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US20110294800 |
HYPOGLYCEMIC DIHYDROPYRIDONES
The present invention provides, inter alia, a compound of formula I: wherein the substituent designations are indicated in the Specification. The present invention also provides pharmaceutical...
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8067462 |
Processes of making sesquiterpenoid tashironin, its analogs and their uses
A compound having the structure of the formula (genus of compound 1 excluding Tashironin or Debenzoyltashironin) and methods of the same.
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8067371 |
RAGE G82S-related methods and compositions for treating inflammatory disorders
This invention provides methods, compositions and articles of manufacture for inhibiting the onset of and treating inflammatory disorders such as rheumatoid arthritis. The instant invention is...
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US20110287056 |
AGENTS AND METHODS TO ELICIT ANTI-TUMOR IMMUNE RESPONSE
The invention provides an isolated, purified population of human cells comprising CD8+ T cells with reduced Cbl-b activity. The invention provides uses of such cells in methods for inducing or...
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US20110286489 |
ALL-SILICON RAMAN AMPLIFIERS AND LASER BASED ON MICRO RING RESONATORS
Devices for generating a laser beam are disclosed. The devices include a silicon micro ring having at least one silicon optical waveguide disposed at a distance from the micro ring. The radius and...
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8063216 |
Photolabile compounds
The present invention describes Photolabile Compounds methods for use of the compounds. The Photolabile Compounds have a photoreleasable ligand, which can be biologically active, and which is...
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US20110281899 |
METHODS OF PREVENTING AND TREATING LOW BONE MASS DISEASES
The present invention provides methods and therapeutic agents for lowering or increasing serum serotonin levels in a patient in order to increase or decrease bone mass, respectively. In preferred...
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8057378 |
Method of treatment of dredged material for beneficial use
A method for the decontamination and solidification of dredged material is described. The method includes, in the following order, (a) adding a lime-based binder to dredged material to form a...
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US20110275156 |
Delivery of DNA or RNA Via Gap Junctions from Host Cells to Target Cells and a Cell-Based Delivery System for Antisense or siRNA
A method of delivering an oligonucleotide or a plasmid expressing an oligonucleotide into a target cell comprises introducing an oligonucleotide into a donor cell, particularly a stem cell, and...
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US20110275062 |
Systems And Methods For Integrating A Single DNA Molecule Into A Molecular Electronic Device
The disclosed subject matter provides a techniques for precisely and/or functionally cutting carbon nanotubes, e.g., single walled carbon nanotubes (“SWNTs”) and integrating a single nucleic aci...
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US20110268884 |
FORMATION OF NANOSCALE CARBON NANOTUBE ELECTRODES USING A SELF-ALIGNED NANOGAP MASK
A first single-wall carbon nanotube can be electrically coupled to a first electrode, and a second single-wall carbon nanotube electrically coupled to a second electrode. In an example, the first...
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8048110 |
Endovascular flexible stapling device
The present invention concerns a flexible stapling device (1). More particularly, this invention concerns a flexible endovascular stapling device (1) for an intravascular procedure such as patent...
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US20110259361 |
DETERGENT COMPOSITIONS UTILIZING HYDROPHOBICALLY MODIFIED POLYMER
Embodiments of the invention relate to a detergent composition including a poly(maleic acid/vinyl octyl ether) (PMAOVE) hydrophobically modified polymer; and a heavy duty liquid detergent. In...
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US20110258939 |
METHODS FOR PRODUCING NANOPARTICLES HAVING HIGH DEFECT DENSITY AND USES THEREOF
The disclosed subject matter is directed to a method for producing nanoparticles, as well as the nanoparticles produced by this method. In one embodiment, the nanoparticles produced by the...
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8043804 |
DBC1, a novel native inhibitor of anti-aging protein SIRT1
A novel complex is identified between the NAD-dependent deacetylase, SIRT1 and its novel inhibitor, DBC1. Provided herein are methods to identify a compound that inhibits the complexation between...
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8043594 |
Systems and methods for generating sulfuric acid
Methods and systems for generating sulfuric acid are disclosed. In some embodiments, the method includes combusting a sulfur-containing material with a gas including oxygen to produce a first...
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US20110258189 |
MULTIMEDIA INTEGRATION DESCRIPTION SCHEME, METHOD AND SYSTEM FOR MPEG-7
The invention provides a system and method for integrating multimedia descriptions in a way that allows humans, software components or devices to easily identify, represent, manage, retrieve, and...
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US20110256112 |
Compensating for Atrioventricular Block Using a Nucleic Acid Encoding a Sodium Channel or Gap Junction Protein
A method of increasing the velocity of AV conduction in a mammal that may be in heart block or at risk of heart block by causing, in an AV node and/or His bundle having less than normal conduction...
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US20110249689 |
DEVICES, SYSTEMS, AND METHODS PROVIDING MICRO-RING AND/OR MICRO-RACETRACK RESONATOR
Provided herein are certain embodiments of systems, methods and devices for Raman lasers based on micro-ring and mircro-racetrack resonators, and the manufacturing thereof. For example, a device...
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8036996 |
Systems and methods for martingale boosting in machine learning
Boosting algorithms are provided for accelerated machine learning in the presence of misclassification noise. In an exemplary embodiment, a machine learning method having multiple learning stages...
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8034698 |
Systems and methods for inducing crystallization of thin films using multiple optical paths
The present invention is directed to systems and methods for irradiating regions of a thin film sample(s) with laser beam pulses having different energy beam characteristics that are generated and...
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US20110244006 |
MICROSPHERE SKIN TREATMENT
This application provides a microsphere suitable for tissue engineering that comprises connective tissue growth factor (CTGF). Also provided is a matrix, material or scaffold suitable for tissue...
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US20110243790 |
MICROFLUIDIC DEVICE FOR COUNTING BIOLOGICAL PARTICLES
A particle counter for analyzing blood has features which provide for automatic operation and preferably, also provide for portable use in a low resource setting. In a preferred embodiment,...
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8030999 |
Low voltage operational transconductance amplifier circuits
Circuits (FIG. 1) that operate with power supplies (VDD) of less than 1 Volt are present. More particularly, circuits (FIG. 1) that operate with supply voltages (VDD) near or lower than the...
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