Patents and Patent Applications from Colorado State University


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9840485 Bisfuran dihalide, method for producing bisfuran dihalide, and method for producing bisfuran diacid, bisfuran diol or bisfuran diamine using bisfuran dihalide  
A bisfuran dihalide having a structure represented by the following formula (1): wherein R1 is a divalent hydrocarbon group represented by —CR2R3— (wherein each of R2 and R3 independently...
9839648 Combined anti-acid-fast bacterial agent, screening method for anti-acid-fast bacterial agents, and activity inhibitor of WecA or ortholog thereof  
A drug combination against acid-fast bacillus, including: an inhibitor for WecA or an ortholog thereof; and at least one of an inhibitor for MurX or an ortholog thereof and an RNA synthesis...
US20170348400 METHODS AND COMPOSITIONS FOR ENHANCING AN IMMUNE RESPONSE, BLOCKING MONOCYTE MIGRATION, AMPLIFYING VACCINE IMMUNITY AND INHIBITING TUMOR GROWTH AND METASTASIS  
Provided are methods of enhancing an immune response and methods for reducing the recruitment of monocytes to a lymph node by administering to an individual an angiotensin II receptor blocker or a...
US20170346134 MULTI-FUNCTIONAL ELECTROLYTE FOR THERMAL MANAGEMENT OF LITHIUM-ION BATTERIES  
The high thermal conduction resistances of a lithium-ion battery (LIB) severely limit the effectiveness of a conventional external thermal management system (TMS). A method for a new thermal...
US20170339989 MEAT AND METHODS OF PREPARING SAME HAVING REDUCED SODIUM CONTENT  
Methods of producing meat compositions with reduced salt content are provided. The process includes providing meat pieces which are bound by cold-binding agents, and in which no salt or reduced...
9828354 Biorefining compounds and organocatalytic upgrading methods  
The invention provides new methods for the direct umpolung self-condensation of 5-hydroxymethylfurfural (HMF) by organocatalysis, thereby upgrading the readily available substrate into...
US20170336320 LASER SENSOR FOR TRACE GAS DETECTION  
Systems and methods are disclosed to determine the concentration of a species within a sample. An example method may include collecting optical loss data over a range of frequencies from the...
9823174 Devices and methods for sorting droplets by surface tension  
A tunable superomniphobic surface with flower-like TiO2 nanostructures was fabricated into a device with precisely tailored surface energy domains that can sort droplets by surface tension. This...
US20170327905 HIGH THROUGHPUT METHOD TO GENOTYPE PLANTS  
Methods are provided for high throughput genotyping of plants, utilizing at least three primers, one primer recognizing a polymorphic sequence of a first species of a plant genus, a second primer...
9809896 Self-assembly of coatings utilizing surface charge  
An apparatus and method for measuring the isoelectric pH for materials deposited on or otherwise affixed onto and in contact with an electrode surface, and a method for utilizing the isoelectric...
9796998 Oxygenase-based biosensing systems for measurement of halogenated alkene concentrations  
A biosensing system that measures the concentration of halogenated alkenes is disclosed.
US20170281754 Compositions and Methods for Enhanced Innate Immunity  
The disclosed compositions and methods relate to an immunogenic composition that, in certain aspects, comprise cationic liposomes; a mixture of toll like receptor 3 (TLR3) and toll like receptor 9...
US20170280859 Personal Sampling Belt  
Implementations described and claimed herein provide an industrial hygiene sampling system including a personal sampling belt and one or more sampling pouches. In one implementation, a belt body...
US20170269001 Oxygenase-Based Biosensing Systems For Measurement Of Halogenated Alkene Concentrations  
A biosensing system that measures the concentration of halogenated alkenes is disclosed.
US20170258962 BONE OR OSTEOCHONDRAL TISSUES AND USES THEREOF  
The present disclosure provides modified bone and osteochondral tissues, methods of preparing modified bone and osteochondral tissues, and methods of using the modified bone or osteochondral...
9758815 Kits for characterization of chromosomal inversions using probes  
A kit for the characterization of chromosomal inversions using single-stranded probes that are either all identical or all complementary to a single-stranded chromatid is described. Reporter...
US20170249404 MITIGATING LATENCY ERRORS IN DISTRIBUTED SYSTEMS  
An example system includes a simulation system that emulates a first portion of an electrical system and controls, based on the first portion, electrical inputs to a device under test. The system...
US20170241353 GASEOUS FUEL CONSUMING ENGINE CONTROLLING SYSTEMS  
According to some embodiments, the present disclosure may relate to a system including a gaseous fuel consuming engine operating at an air to fuel ratio (AFR) and including a throttle valve...
9741999 Lithium-ion battery  
A lithium-ion battery having an anode including an array of nanowires electrochemically coated with a polymer electrolyte, and surrounded by a cathode matrix, forming thereby interpenetrating...
9739709 Hydrocarbon sensing methods and apparatus  
A chip-scale, reusable sensor can detect aromatic hydrocarbons, such as benzene, toluene, ethylbenzene, and xylenes (BTEX), rapidly in water without sample preparation. The device is capable of...
US20170232252 TONGUE STIMULATION FOR COMMUNICATION OF INFORMATION TO A USER  
Example devices and methods of tongue stimulation for communication of information to a user are disclosed herein. In an example, a tongue stimulation device may include a body configured to be...
US20170226583 IDENTIFICATION OF CATTLE AT RISK OF HIGH ALTITUDE PULMONARY HYPERTENSION  
Provided herein are methods and compositions for determining the susceptibility of cattle to High Altitude Pulmonary Hypertension. Also provide are kits and reagents for performing such methods.
US20170212044 Hydrocarbon Sensing Methods and Apparatus  
A chip-scale, reusable sensor can detect aromatic hydrocarbons, such as benzene, toluene, ethylbenzene, and xylenes (BTEX), rapidly in water without sample preparation. The device is capable of...
US20170204163 COMPOSITIONS COMPRISING RESURFACED CELL-PENETRATING NANOBODIES AND METHODS OF USE THEREOF  
The disclosure encompasses resurfaced cell-penetrating nanobodies and their methods of use. The resurfacing of nanobodies with positively-charged amino acids facilitates their penetration into a...
US20170198363 COMPOSITIONS AND METHODS FOR DETECTION OF SMALL MOLECULES  
Compositions and methods are provided for the detection of small molecules in a cell using biosensor molecules comprising conditionally active ligand binding domains. Compositions for...
US20170189583 POLYMERIC MATERIALS INCLUDING A GLYCOSAMINOGLYCAN NETWORKED WITH A POLYOLEFIN-CONTAINING POLYMER  
The present invention relates to polymeric materials including a glycosaminoglycan networked with a polyolefin-containing polymer. The present invention also relates to hydrogels containing the...
US20170184483 METHOD AND DEVICE FOR INCOHERENT IMAGING WITH COHERENT DIFFRACTIVE RECONSTRUCTION  
Systems and methods are disclosed to determine the axial and/or lateral location of a particle using light modulated with temporal and/or spatial modulation pattern. The system, for example, may...
9692083 Lithium-ion battery having organic-inorganic hybrid solid electrolyte  
Methods are described for forming insulating hybrid organic-inorganic solid electrolytes on conducting electrodes that are active materials in Li-ion batteries by electrochemical deposition, and...
US20170176311 DEVICES AND METHODS FOR SORTING DROPLETS BY SURFACE TENSION  
A tunable superomniphobic surface with flower-like TiO2 nanostructures was fabricated into a device with precisely tailored surface energy domains that can sort droplets by surface tension. This...
9683992 Ligand passivated gold nanoparticles  
The invention provides novel gold nanoclusters of the formula Au20(SR)15(weak ligand), wherein each R is independently an organic group, and the weak ligand is a weakly associating gold ligand of...
US20170158824 REVERSIBLE METALLOPOLYMER NETWORK  
The invention provides a metallopolymer coordination network comprising one or more coinage or similar metals and a glyme or glyme-equivalent. The composition has an amorphous polymer network that...
9671334 Multi-analyte optical sensor  
An analyte-detection system has an optical waveguide with first and second cladding layers adjacent a core; a light source coupled to provide light to the waveguide; a photodetector such as a...
9669159 Tongue stimulation for communication of information to a user  
Example devices and methods of tongue stimulation for communication of information to a user are disclosed herein. In an example, a tongue stimulation device may include a body configured to be...
9650656 Biosynthetic systems producing fungal indole alkaloids  
The biosynthesis of fungal bicyclo[2.2.2]diazaoctane indole alkaloids with a wide spectrum of biological activities have attracted increasing interest. Their intriguing mode of assembly has long...
9637714 Diffuse light extended surface area water-supported photobioreactor  
A scalable photobioreactor system for efficient production of photosynthetic microorganisms such as microalgae and cyanobacteria is described. In various embodiments, this system may include the...
9636149 Pedicle screw assembly and dynamic spinal stabilization devices incorporating the pedicle screw assembly  
A dynamic spinal stabilization device for the treatment of high-grade spinal disorders is disclosed herein. The dynamic spinal stabilization device includes two or more screw assemblies, each of...
US20170101516 MATERIAL COMPRISING OUTER LAYER HAVING ENTANGLEMENT OF HYDROPHOBIC POLYMER HOST BLENDED WITH ANHYDRIDE FUNCTIONALIZED HYDROPHOBIC POLYMER CO-HOST AND HYDROPHILIC GUEST  
The present disclosure provides, inter alia, a method of producing an outer layer material for forming into a structure and that comprises an entanglement having a hydrophobic polymer host and a...
9618439 Thermophoretic sampler  
A thermophoretic sampler includes a sample assembly into which a removable sample cartridge can be inserted. The sample cartridge holds a substrate that, upon insertion, is exposed to a sample...
9611491 Biosynthetic pathway for heterologous expression of a nonribosomal peptide synthetase drug and analogs  
The present invention is directed to the biosynthetic pathway for a nonribosomal peptide synthetase (NRPS) derived drug and analogs thereof. The invention also discloses polynucleotide sequences...
9603633 Interspinous spacer devices for dynamic stabilization of degraded spinal segments  
An interspinous spacer device for the treatment of high-grade spinal disorders is disclosed herein. The interspinous spacer device includes a sliding rod and a base that contains a curved internal...
US20170081697 METHODS FOR IMPROVED IN VITRO - IN VIVO EFFICACY DETERMINATION  
A method is presented for treating herpes simplex virus (HSV) infection comprising: (a) locally administering a substance that induces a delayed type hypersensitivity (DTH) response to a patient...
9597434 Surface treatments for vascular stents and methods thereof  
Surface modified medical devices with nanotubes and polyelectrolyte multilayers, methods of promoting endothelialization, and methods of modifying a medical device surface are disclosed. Nanotubes...
US20170069197 FIRE ALARM SYSTEM  
A fire alarm control and monitoring system is disclosed. In some embodiments, the fire alarm and control system may include a plurality of fire alarm control panels connected together through a...
US20170059585 In vitro detection of prions in blood  
A method of screening a blood sample for the presence of prions. The method includes the steps of collecting the blood sample in heparin, contacting the sample with a solution comprising...
US20170046985 SYSTEMS AND METHODS FOR PALPATION TRAINING  
Implementations described and claimed herein provide systems and methods for palpation training. In one implementation, a system for medical procedure simulation includes an examination model, a...
US20170045272 ULTRA EFFICIENT TURBO-COMPRESSION COOLING  
A turbo-compression cooling system includes a power cycle and a cooling cycle coupled one to the other. The power cycle implements a waste heat waste heat exchanger configured to evaporate a first...
US20170044124 BIOREFINING COMPOUNDS AND ORGANOCATALYTIC UPGRADING METHODS  
The invention provides new methods for the direct umpolung self-condensation of 5-hydroxymethylfurfural (HMF) by organocatalysis, thereby upgrading the readily available substrate into...
9567447 Outer layer having entanglement of hydrophobic polymer host and hydrophilic polymer guest  
An outer layer having an entanglement comprising an intermingling of cloaked hydrophilic guest and a hydrophobic polymer host, wherein molecules of the guest have been crosslinked with each other....
US20170028390 METAL-ORGANIC FRAMEWORK FUNCTIONALIZED POLYMERIC COMPOSITIONS  
A polymeric composition includes an organic polymeric substrate and metal-organic frameworks on the surface of the polymeric substrate. The metal-organic frameworks cover at least 90% of the...
9552952 12CaO-7Al2O3 electride hollow cathode  
The use of the electride form of 12CaO-7Al2O3, or C12A7, as a low work function electron emitter in a hollow cathode discharge apparatus is described. No heater is required to initiate operation...