Patents and Patent Applications from Colorado State University


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10024797 Biosensing systems for measurement of lactose  
Herein disclosed are biosensing systems that measure lactose concentration in a solution.
10018634 Sensors and assays for ubiquitin or ubiquitin-like proteins  
The present invention provides compositions comprising chimeric polypeptides that bind to free ubiquitin proteins or free ubiquitin-like proteins with high affinity, as well as chimeric...
US20180185326 USE OF EQUOL FOR TREATING ANDROGEN MEDIATED DISEASES  
Equol (7-hydroxy-3(4′hydroxyphenyl)-chroman), or metabolite of the phytoestrogen daidzein, specifically binds and blocks the hormonal action of 5α-dihydrotestosterone (DHT) in vitro and in vivo....
US20180174432 FIRE ALARM SYSTEM  
A method may include gathering data from a first set of sensors disposed throughout a first facility at a first fire alarm control panel. The method may also include exchanging one or more...
US20180172668 ENGINEERED MODEL OF FIBROTIC DISEASES  
The present disclosure provides co-cultures of a population of hepatocytes, at least one non-parenchymal cell population, and a population of hepatic stellate cells in vitro, methods of preparing...
10002738 Simplified formation process of a low work function insert  
In an example, a method to form a low work function insert includes preparing a mixture that includes a first powder that contains barium, a second powder that contains calcium, a third powder...
9996843 Nano-stamp and matched reader for anti-counterfeiting applications  
A method and system for reading a security seal having a unique far-field pattern are described. Periodic nano-structure is generated on the surface of a substrate having spacings of hundreds of...
9993641 Tongue stimulation for communication of information to a user  
Example devices and methods of tongue stimulation for communication of information to a user are disclosed herein. In an example, a tongue stimulation device may include a body configured to be...
US20180141878 SYNERGISTIC BACTERIAL CONSORTIA FOR MOBILIZING SOIL PHOSPHORUS  
The present disclosure relates to consortia of bacteria strains and composition comprising one or more bacterial strains disclosed herein. These consortia of isolated bacteria cultures and...
US20180127468 ANTI-HIV PEPTIDES  
The present disclosure provides simple β-hairpin peptides in linear and cyclic form that specifically bind to HIV-1 Trans-Activation Response element (HIV-1 TAR), as well as compositions and use...
9963750 High throughput method to genotype plants  
Methods are provided for high throughput genotyping of plants, utilizing at least three primers, one primer recognizing a polymorphic sequence of a first species of a plant genus, a second primer...
US20180118880 RING-OPENING POLYMERIZATION METHODS AND RECYCLABLE BIORENEWABLE POLYESTERS  
The invention provides polymers of Formulas I-III, such as polyesters and unsaturated polyesters, and crosslinked and copolymerized polymers thereof. The invention also provides methods to...
US20180113072 Hydrocarbon Sensing Methods and Apparatus  
A chip-scale, reusable sensor can detect aromatic hydrocarbons, such as benzene, toluene, ethylbenzene, and xylenes (BTEX), rapidly in water without sample preparation. The device is capable of...
US20180105825 SYNTHETIC REPRESSION OF GENE EXPRESSION IN PLANTS  
The present disclosure provides synthetic repressor constructs and the proteins encoded therein, as well as synthetic repressible promoter constructs for use in combination with the synthetic...
9947961 Multi-functional electrolyte for thermal management of lithium-ion batteries  
The high thermal conduction resistances of a lithium-ion battery (LIB) severely limit the effectiveness of a conventional external thermal management system (TMS). A method for a new thermal...
9934929 Hall current plasma source having a center-mounted or a surface-mounted cathode  
A miniature Hall current plasma source apparatus having magnetic shielding of the walls from ionized plasma, an integrated discharge channel and gas distributor, an instant-start hollow cathode...
9933437 Early determination of pregnancy status in ruminants  
The present invention provides compositions and methods for detection schemes for ascertaining pregnancy status of an animal. The compositions and methods employ interferon-tau (IFNT) and/or...
US20180087085 METHODS FOR IMPROVED IN VITRO - IN VIVO EFFICACY DETERMINATION  
The invention provides methods for determining and evaluating the in vitro-in vivo activity relationship of the efficacy of families of compounds for infectious diseases such as tuberculosis. The...
US20180085445 OPTIMIZED CANCER STEM CELL VACCINES  
The present invention provides cancer stem cell vaccines useful for treating or preventing a variety of tumors, as well as related methods of producing cancer stem cells and antigens thereof and...
D812344 Personal sampling belt  
US20180057510 Synthesis and Utility of New Capgroup Largazole Analogs  
Analogs of largazole are described herein. Methods of treating cancer, blood disorders, autoimmune disease, and Alzheimer's Disease using largazole analogs and pharmaceutical compositions...
9905119 Fire alarm system  
A fire alarm control and monitoring system is disclosed. In some embodiments, the fire alarm and control system may include a plurality of fire alarm control panels connected together through a...
US20180051139 PHOTOTUNABLE THERMOPLASTIC ELASTOMER HYDROGEL NETWORKS  
Provided herein is a thermoplastic elastomer hydrogel and methods of making such. The hydrogel comprises a glass formed from poly(styrene)-b-poly(ethylene oxide) in which the coronal chain end has...
9896712 Biosensing system with extended lifetime via cofactor recycling  
The present disclosure relates to biosensing systems and biosensing elements having increased storage capability and increased functional lifetimes through using compositions and methods for...
US20180044376 Method for Preparing Largazole Analogs and Uses Thereof  
Analogs of largazole are described herein. Methods of treating cancer and blood disorders using largazole and largazole analogs and pharmaceutical compositions comprising the same are additionally...
9891167 Optical analyte sensor  
A waveguide sensor capable of direct, real-time detection and monitoring of analytes in the vicinity of the waveguide surface without requiring the tagging or labeling of the analyte, is...
9889116 Use of equol for treating androgen mediated diseases  
Equol (7-hydroxy-3(4′hydroxyphenyl)-chroman), the major metabolite of the phytoestrogen daidzein, specifically binds and blocks the hormonal action of 5α-dihydrotestosterone (DHT) in vitro and in...
US20180036283 INDOLE-BASED THERAPEUTICS  
Provided herein are indole-2-carboxamide compounds useful for the treatment of non-tuberculosis bacterial infections. Exemplary compounds provided herein are useful for the treatment of...
9868675 Synergistic bacterial consortia for mobilizing soil phosphorus  
The present disclosure relates to consortia of bacteria strains and composition comprising one or more bacterial strains disclosed herein. These consortia of isolated bacteria cultures and...
US20180000901 USE OF PEPTIDE-BASED INHIBITORS OF THE STAT3-IL10 PATHWAY FOR TREATING BACTERIAL INFECTION AND GRANULOMATOUS DISEASE  
The invention provides a method of treating pathogenic bacterial infection (e.g., tuberculosis infection) in an animal comprising administering a peptide-based inhibitor of the STAT3-IL10 pathway...
9857299 Hydrocarbon sensing methods and apparatus  
A chip-scale, reusable sensor can detect aromatic hydrocarbons, such as benzene, toluene, ethylbenzene, and xylenes (BTEX), rapidly in water without sample preparation. The device is capable of...
US20170370809 PORTABLE AIR SAMPLING DEVICE  
A sampling device is constructed having an airflow path from a size-selective inlet to a device outlet, without using any tubing. The size-selective inlet includes at least one of an impactor, a...
US20170362908 CRYOGENIC CORE COLLECTION  
A system and method for collecting a core sample. The system includes an outer cylindrical tube, a drive head, a drive shoe, a cooling chamber housed inside the outer cylindrical tube, insulation,...
US20170362282 ENGINEERED PROGRAMMABLE MOLECULAR SCAFFOLDS FROM POROUS PROTEIN CRYSTALS  
The present disclosure provides compositions and methods for preparing engineered porous protein crystals comprising at least one guest molecule.
9840485 Bisfuran dihalide, method for producing bisfuran dihalide, and method for producing bisfuran diacid, bisfuran diol or bisfuran diamine using bisfuran dihalide  
A bisfuran dihalide having a structure represented by the following formula (1): wherein R1 is a divalent hydrocarbon group represented by —CR2R3— (wherein each of R2 and R3 independently...
9839648 Combined anti-acid-fast bacterial agent, screening method for anti-acid-fast bacterial agents, and activity inhibitor of WecA or ortholog thereof  
A drug combination against acid-fast bacillus, including: an inhibitor for WecA or an ortholog thereof; and at least one of an inhibitor for MurX or an ortholog thereof and an RNA synthesis...
US20170348400 METHODS AND COMPOSITIONS FOR ENHANCING AN IMMUNE RESPONSE, BLOCKING MONOCYTE MIGRATION, AMPLIFYING VACCINE IMMUNITY AND INHIBITING TUMOR GROWTH AND METASTASIS  
Provided are methods of enhancing an immune response and methods for reducing the recruitment of monocytes to a lymph node by administering to an individual an angiotensin II receptor blocker or a...
US20170346134 MULTI-FUNCTIONAL ELECTROLYTE FOR THERMAL MANAGEMENT OF LITHIUM-ION BATTERIES  
The high thermal conduction resistances of a lithium-ion battery (LIB) severely limit the effectiveness of a conventional external thermal management system (TMS). A method for a new thermal...
US20170339989 MEAT AND METHODS OF PREPARING SAME HAVING REDUCED SODIUM CONTENT  
Methods of producing meat compositions with reduced salt content are provided. The process includes providing meat pieces which are bound by cold-binding agents, and in which no salt or reduced...
9828354 Biorefining compounds and organocatalytic upgrading methods  
The invention provides new methods for the direct umpolung self-condensation of 5-hydroxymethylfurfural (HMF) by organocatalysis, thereby upgrading the readily available substrate into...
US20170336320 LASER SENSOR FOR TRACE GAS DETECTION  
Systems and methods are disclosed to determine the concentration of a species within a sample. An example method may include collecting optical loss data over a range of frequencies from the...
9823174 Devices and methods for sorting droplets by surface tension  
A tunable superomniphobic surface with flower-like TiO2 nanostructures was fabricated into a device with precisely tailored surface energy domains that can sort droplets by surface tension. This...
US20170327905 HIGH THROUGHPUT METHOD TO GENOTYPE PLANTS  
Methods are provided for high throughput genotyping of plants, utilizing at least three primers, one primer recognizing a polymorphic sequence of a first species of a plant genus, a second primer...
9809896 Self-assembly of coatings utilizing surface charge  
An apparatus and method for measuring the isoelectric pH for materials deposited on or otherwise affixed onto and in contact with an electrode surface, and a method for utilizing the isoelectric...
9796998 Oxygenase-based biosensing systems for measurement of halogenated alkene concentrations  
A biosensing system that measures the concentration of halogenated alkenes is disclosed.
US20170281754 Compositions and Methods for Enhanced Innate Immunity  
The disclosed compositions and methods relate to an immunogenic composition that, in certain aspects, comprise cationic liposomes; a mixture of toll like receptor 3 (TLR3) and toll like receptor 9...
US20170280859 Personal Sampling Belt  
Implementations described and claimed herein provide an industrial hygiene sampling system including a personal sampling belt and one or more sampling pouches. In one implementation, a belt body...
US20170269001 Oxygenase-Based Biosensing Systems For Measurement Of Halogenated Alkene Concentrations  
A biosensing system that measures the concentration of halogenated alkenes is disclosed.
US20170258962 BONE OR OSTEOCHONDRAL TISSUES AND USES THEREOF  
The present disclosure provides modified bone and osteochondral tissues, methods of preparing modified bone and osteochondral tissues, and methods of using the modified bone or osteochondral...
9758815 Kits for characterization of chromosomal inversions using probes  
A kit for the characterization of chromosomal inversions using single-stranded probes that are either all identical or all complementary to a single-stranded chromatid is described. Reporter...