Patents and Patent Applications from Case Western Reserve University


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US20120001630 DARK BLOOD BALANCED STEADY STATE FREE PRECESSION IMAGING  
Systems, methods, and other embodiments associated with controlling a magnetic resonance imaging (MRI) apparatus to perform a balanced steady state free precession (bSSFP) technique that includes...
US20110311158 MOTION ARTIFACT REMOVAL  
Systems, methods, and other embodiments associated with removing motion artifacts from MR images are described. One example method includes controlling an MRI apparatus to acquire a fully sampled,...
US20110305638 Modulation of Macrophage Activation  
The invention provides methods for treating pathological conditions associated with an undesirable inflammatory component. The invention is generally directed to reducing inflammation by...
8078264 Intra-operative molecular imaging  
A system for imaging an abnormal cell and or diseased tissue after topical application of a near infrared protease-specific probe is disclosed. The system includes a protease-specific near infrared...
8076088 Method of detecting human β-defensins  
A method of detecting β-defensin in a bodily sample from a subject includes reducing the electrostatic interaction between β-defensin and negatively charged moieties in the bodily sample prior to d...
8073230 Systems and methods for generating images for identifying diseases  
Systems and methods for generating images for identifying diseases are provided. In one embodiment, a method comprises receiving a first digital radiography (DR) image of at least a portion of a...
US20110293578 Use of Stem Cells to Prevent Neuronal Dieback  
The invention is generally directed to treatment of neuronal injury. In particular, the invention is directed to reducing axonal retraction (“dieback”) that occurs as a result of the int...
US20110279118 CONTROLLING MULTI-CHANNEL TRANSMITTER EFFECTS ON SPECIFIC ABSORPTION RATE  
Systems, methods, and other embodiments associated with controlling the specific absorption rate (SAR) in a patient associated with a conductor are described. The conductor may be, for example, a...
8060208 Action potential conduction prevention  
An example method for selectively and reversibly preventing the conduction of action potentials in a targeted nerve region is presented. The method includes generating an electrical waveform having...
8059907 Constant variance filter  
Systems and methods associated with a constant variance filter are described. One system embodiment includes a memory to store a spatially dependent filtered data set having a first degree of...
RE42887 Silicon carbide and other films and method of deposition  
A method of depositing a ceramic film, particularly a silicon carbide film, on a substrate is disclosed in which the residual stress, residual stress gradient, and resistivity are controlled. Also...
8050669 Beacon group merging  
A method of merging two or more beacon groups (BGs), each BG comprising one or more wireless devices, the method comprising, determining a leader BG based on merging information broadcast by two or...
8049500 Dynamically selectively configuring wireless transmitter associated with MRI detector coil  
Systems, methods, and other embodiments associated with dynamically selectively configuring wireless transmitters associated with MRI detector coils are described. One example apparatus includes a...
8049499 Controlling multi-channel transmitter effects on specific absorption rate  
Systems, methods, and other embodiments associated with controlling the specific absorption rate (SAR) in a patient associated with a conductor are described. The conductor may be, for example, a...
US20110264178 Probe for Neural Stimulation  
A neural probe for stimulating neural tissue is disclosed. The probe comprises a three-dimensional arrangement of individually addressable electrodes. As a result, embodiments of the present...
8046047 Extended-coverage imaging coil  
Extended-coverage magnetic resonance imaging coils with optimized homogeneity in longitudinal sensitivity are described. One exemplary coil includes four elements, where two of the elements are...
8034779 Inhibitors of BCL-2  
A purified polypeptide includes an amino acid sequence consisting of about 10 to 80 amino acids, the amino acid sequence having a sequence identity at least 90% homologous to a portion of SEQ ID...
US20110241685 SWITCHED MODE PRE-AMPLIFICATION AND AM FEEDBACK FOR ON-COIL SWITCHED MODE AMPLIFIERS IN PARALLEL TRANSMISSION MRI  
Example systems, apparatus, circuits, and so on described herein concern parallel transmission in MRI with on-coil current-mode (CMCD) amplifiers. One example apparatus includes switched...
US20110241682 ON-COIL CURRENT MODE CLASS D RF POWER AMPLIFIER IN HIGH FIELD PARALLEL TRANSMISSION MRI  
Example systems, apparatus, circuits, and so on described herein concern parallel transmission in high field MRI. One example apparatus includes a balun network that produces out-of-phase signals...
US20110241681 HALL EFFECT CURRENT SENSOR  
Example systems, apparatus, circuits, and so on described herein concern a Hall effect current sensor that includes a planar portion of a conductor that is oriented perpendicular to a base magnetic...
8030921 Methods for fat signal suppression in magnetic resonance imaging  
This application is directed to methods for chemical species signal suppression in magnetic resonance imaging procedures, where Dixon techniques are enhanced by continuously sampling techniques....
8030919 Dark blood balanced steady state free precession imaging  
Systems, methods, and other embodiments associated with controlling a magnetic resonance imaging (MRI) apparatus to perform a balanced steady state free precession (bSSFP) technique that includes...
8029942 Fuel cell system with flow field capable of removing liquid water from the high-pressure channels  
A fuel cell system having flow fields capable to operate like interdigitated flow fields, but in the same time allowing the removal of liquid water collected in the high-pressure channels,...
8026488 Methods for positive emission tomography (PET) target image segmentation  
A method for positive emission tomography (PET) target image segmentation is provided. The method comprises capturing and digitizing image data of a selected target, determining an initial...
US20110217708 METHODS AND COMPOSITIONS FOR DETECTING COLON CANCERS  
This application describes methods and compositions for detecting and treating vimentin-associated neoplasia. Differential methylation of the vimentin nucleotide sequences has been observed in...
RE42641 Depth-resolved spectroscopic optical coherence tomography  
A method is described for determining depth-resolved backscatter characteristics of scatterers within a sample, comprising the steps of: acquiring a plurality of sets of cross-correlation...
8005472 Method of reporting poor RF coverage in a wireless network  
The present invention provides a method for storing data relating to network conditions in a mobile unit. A mobile station receives a signal from a base station. The mobile station stores data...
US20110195896 ISOFORM-SPECIFIC INSULIN ANALOGUES  
A method treating a mammal by administering a physiologically effective amount of an insulin analogue or a physiologically acceptable salt thereof where the insulin analogue displays more than...
7996062 Double-contrast technique for MRI-guided vascular interventions  
Methods for confirming location of a catheter tip relative to a targeted location in a blood vessel of a subject and improving visualization of the blood vessels downstream of the catheter tip are...
US20110175610 NON-CARTESIAN UNDER-SAMPLED MULTI-ECHO MRI  
Example apparatuses and methods control a magnetic resonance imaging (MRI) apparatus to perform a non-Cartesian, under-sampled, multi-echo MRI process. One example process includes controlling the...
7983743 System and method for noninvasive electrocardiographic imaging (ECGI)  
Noninvasive systems and methods are provided for determining electrical activity for a heart of a living being. A processor is configured to meshlessly compute data that represents heart electrical...
US20110166064 HALOGEN-STABILIZED INSULIN  
An insulin analogue comprises a B-chain polypeptide incorporating a halogenated phenylalanine at position B24, B25 or B26. The halogenated phenylalanine may be ortho-monofluoro-phenylalanine,...
US20110165058 Growth of Single-walled Carbon Nanotubes  
A method for synthesizing carbon nanotubes having a narrow distribution of diameter and/or chirality is presented. The method comprises providing catalyst particles to a reactor for synthesizing...
7972845 Human antibodies against Pseudomonas aeruginosa LPS derived from transgenic xenomouse  
The invention described herein provides for human antibodies produced in non-human animals that specifically bind to Pseudomonas aeruginosa Lipopolysaccharide (LPS). The invention further provides...
US20110160798 SEPARATED-INTERFACE NERVE ELECTRODE  
Example ionic coupling electrodes are described. One example ionic conducting electrode includes a first portion that can be coupled to a single phase current source. The first portion carries...
7964585 Composition and method of treating peripheral neuropathy  
A method of treating diabetic neuropathy in a subject includes administering to a subject having diabetes or at risk of diabetes a therapeutically effective amount of a pharmaceutical composition...
7964390 Sensor system  
A sensor probe suited for implanting into the skin of a person includes a sensor body which may be formed from a polymer which includes 2-hydroxyethyl methacrylate (HEMA). A sensing system is...
7964353 Methods and compositions for detecting colon cancers  
This application describes methods and compositions for detecting and treating vimentin-associated neoplasia. Differential methylation of the vimentin nucleotide sequences has been observed in...
US20110125216 ADJUSTABLE NERVE ELECTRODE  
Example adjustable electrodes are described. One example adjustable electrode includes two or more contacts configured to selectively deliver high frequency alternating current (HFAC) to a nerve in...
7949384 Method to correct magnetic field/phase variations in proton resonance frequency shift thermometry in magnetic resonance imaging  
PRF shift MRI data is acquired. The PRF shift MRI data may include signals affected by both a desired PRF shift and an undesired PRF shift. Thus, example systems and methods describe manipulating...
7947802 Benzoxazine monomers, polymers and compositions  
Benzoxazine monomers comprising at least one pendant group are described. (Co)Polymers comprising at least one benzoxazine monomer having at least one pendant group are also described. In a...
7943675 Electrolytes for fuel cell electrodes  
Improved polymer-based materials are described, for example for use as an electrode binder in a fuel cell. A fuel cell according to an example of the present invention comprises a first electrode...
7940044 Determining phase-encoding direction for parallel MRI  
Example systems, methods, and apparatus associated with determining a phase-encoding direction for parallel MRI are described. One example, method includes selecting a set of projection directions...
7936802 Co-extruded multilayer polymers films for all-polymer lasers  
A polymer film laser is provided that comprises a plurality of extruded polymer layers. The plurality of extruded polymer layers comprises a plurality of alternating dielectric layers of a first...
7935745 Self-assembled nanofiber templates; versatile approaches for polymer nanocomposites  
Polymer nanocomposites, nanoparticle-containing organogels utilized in forming the polymer nanocomposites, and methods for forming the polymer nanocomposites and nanoparticle-containing organogels...
US20110096092 NON-CARTESIAN CAIPIRINHA  
Example systems, methods, and apparatus concern non-Cartesian CAIPIRINHA (Controlled Aliasing In Parallel Imaging Results IN Higher Acceleration). One example parallel magnetic resonance imaging...
US20110093233 THROUGH-TIME RADIAL GRAPPA CALIBRATION  
Example systems and methods control a parallel magnetic resonance imaging (pMRI) apparatus to acquire radial calibration data sets throughout time. Example systems and methods also control the pMRI...
US20110089946 THROUGH-TIME NON-CARTESIAN GRAPPA CALIBRATION  
Example systems and methods control a parallel magnetic resonance imaging (pMRI) apparatus to acquire non-Cartesian (e.g., spiral) calibration data sets throughout time. Example systems and methods...
7929134 Even frequency spacing spectrometer and optical coherence tomography device  
This application describes a spectrometer that includes a set of collimating optics to collimate received EMR to produce a collimated EMR. The spectrometer also includes a first dispersive optical...
US20110082188 GENE EXPRESSION PROFILING OF INFLAMMATORY BOWEL DISEASE  
The present invention relates to methods for identifying and/or classifying patients with inflammatory bowel diseases (IBD), particularly patients with Crohn's disease or ulcerative colitis. Gene...