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5770374 |
Methods for identifying oncogenes and anti-oncogenes
Episomal plasmids containing a papovavirus origin of replication and a papovavirus large T antigen mutant form are shown to replicate episomally in human cells, and yield levels of gene expression...
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5769875 |
Functional neuromusclar stimulation system
An input command controller (A) provides logic function selection signals and proportional signals. The signals are generated by movement of a ball member (12) and socket member (14) relative to...
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5767668 |
Remote current sensor
A remote non-invasive current sensing apparatus for sensing current being carried through a conductor located beneath or on top of a surface. First and second magnetic field sensor elements are...
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5750210 |
Hydrogenated carbon composition
A composition of matter having an atomic density between that of pure diamond and at least 0.18 g-atoms per cubic centimeter and the formula: C1-z-w Siz Aw H1-x Fx !ywhere: 0≤z+w≤0.15, 0≤w...
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5741852 |
Nonthrombogenic implant surfaces
Triblock polymers comprised of polysaccharide, such as heparin or dextran, and a hydrocarbon chain, have been prepared. The triblock polymer adsorbs strongly on the surface of hydrophobic polymer...
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5736396 |
Lineage-directed induction of human mesenchymal stem cell differentiation
Methods for in vitro or ex vivo lineage directed induction of isolated, culture expanded human mesenchymal stem cells comprising contacting the mesenchymal stem cells with a bioactive factor...
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5731416 |
Peptide based nucleic acid surrogates
The present invention relates to the development of a new class of oligonucleotide surrogates capable of sequence specific binding to simple stranded DNA and RNA as well as to double stranded DNA...
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5716727 |
Proton conducting polymers prepared by direct acid casting
A method for casting solid polymer electrolyte membranes comprising proton conducting polymers stable at temperatures in excess of 100° C. directly from acid solution. The invention further ...
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5712609 |
Micromechanical memory sensor
A micromechanical memory sensor. The sensor comprises a latch member mechanically latching upon detection of a threshold value of a variable condition and circuitry for detecting such latching. A...
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5709207 |
Audio information incorporated within MRI pulse sequences
Audio information is spoken into a microphone and saved in digitized form in an electronic file. The digitized information is converted into a format which is usable within a particular MRI system....
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5705318 |
Micromotors and methods of fabrication
A polysilicon micromotor, of either inner rotor or outer rotor design, is fabricated with a process that uses as few as three mask steps. In an outer rotor (wobble) micromotor, a free-rotating...
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5695967 |
Method for stably cloning large repeating units of DNA
A direction method of stably cloning large repeating units of DNA is described. The method is especially useful for the stable cloning of alpha satellite DNA.
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5689877 |
Method of manufacturing an implantable helical spiral cuff electrode
A self-curling elongate non-conductive sheet (A) defines a helical cuff electrode (10). A plurality of contact members (40) are linearly disposed along a direction (C) between a first layer (30)...
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5686250 |
Antibodies to LGE2 -protein antigens
Levuglandin (LG) derivatives are used as antigens for raising antibodies useful in diagnostic assays. The antibodies produced by LG-carrier protein adducts can be used to detect adducts of LGE2...
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5667962 |
Pyruvate thiolester for the prevention of reperfusion injury
The invention comprises a novel pyruvate compound for the treatment or prevention of reperfusion injury following ischemia. The novel pyruvate compound is particularly a pyruvate thiolester....
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5643736 |
Monoclonal antibodies for human osteogenic cell surface antigens
Monoclonal antibodies specific for normal human osteogenic cell subsets and the monoclonal hybridoma cell lines that synthesize and secrete these monospecific antibodies, as well as the uses of the...
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5634462 |
Corrugated inter-fascicular nerve cuff method and apparatus
A corrugated sheet of non-conductive biocompatible material is biased to circumferentially contract around a nerve or other body tissue. Conductive members are disposed on inwardly projecting...
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5624820 |
Episomal expression vector for human gene therapy
Episomal plasmids containing a papovavirus origin of replication and a papovavirus large T antigen mutant form are shown to replicate episomally in human cells, and yield levels of gene expression...
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5605982 |
Sheet and tube siloxane polymers
Organopolysiloxane sheet or tube polymers are made by contacting a sheet or tube silicate with an alkenyl group containing chlorosilane to form an alkenylsiloxy polymer, and subsequently contacting...
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5602662 |
Cholesteric liquid crystal devices
A liquid crystal cell including chiral nematic liquid material with negative dielectric anisotropy. The cell is placed between two orthogonal polarizers. In the absence of an applied field, the...
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5602110 |
Method and composition for treating cystic fibrosis
A method and composition for treating cystic fibrosis comprising administering to a patient a first component, a second component, and preferably a third component. The first component is an...
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5591625 |
Transduced mesenchymal stem cells
Genetically engineered human stem cells that carry within them genes of interest particularly for the expression of physiologically or pharmacologically active proteins or for use in gene therapy....
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5585311 |
Capacitive absolute pressure sensor and method
A capacitive absolute pressure sensor. The sensor includes a substrate having an electrode deposited thereon and a diaphragm assembly disposed on the substrate. As pressure increases, the diaphragm...
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5545432 |
Synthesis of metal oxide thin films
Oxide thin films are deposited onto functionalized self-assembled monolayers (SAMs) which are bonded to various surfaces. The resulting oxide thin films have ordered, uniform densely packed...
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5528452 |
Capacitive absolute pressure sensor
A capacitive absolute pressure sensor. The sensor includes a substrate having an electrode deposited thereon and a diaphragm assembly disposed on the substrate. As pressure increases, the diaphragm...
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5525436 |
Proton conducting polymers used as membranes
The subject invention relates to solid polymer electrolyte membranes comprising proton conducting polymers stable at temperatures in excess of 100° C., the polymer being basic polymer complexed ...
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5505201 |
Implantable helical spiral cuff electrode
A self-curling elongate non-conductive sheet (A) defines a helical cuff electrode (10). A plurality of contact members (40) are linearly disposed along a direction (C) between a first layer (30)...
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5487889 |
Bandage for continuous application of biologicals
The present invention provides a biological bandage, comprising an envelope enclosing cells which secrete biologically active cellular products such as growth factors, which promote the healing of...
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5480807 |
Process for assessing the biological age of a tissue
The present invention is directed to use of an imidazo [4,5b] pyridinium molecule composed of a lysine and an arginine residue crosslinked with a pentose sugar for assessing the biological age of a...
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5477358 |
Chiral nematic liquid crystal display with homeotropic alignment and negative dielectric anisotropy
A liquid crystal cell including chiral nematic liquid material with negative dielectric anisotropy. The cell is placed between two orthogonal polarizers. In the absence of an applied field, the...
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5472438 |
Laproscopic vacuum delivery apparatus for a diaphragm daper
A laparoscopic vacuum delivery device is used for placing an epimysial electrode at the phrenic nerve motor point. The vacuum delivery device is adapted to hold the epimysial electrode while the...
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5466247 |
Subcutaneous electrode for stimulating skeletal musculature
A subcutaneously implantable device is provided for either electrically stimulating skeletal musculature or sensing electrical potential at its surface without directly contacting the musculature....
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5455040 |
Anticoagulant plasma polymer-modified substrate
The present invention provides a method for surface modifying a substrate, such as an implant, to provide the substrate with anticoagulant activity and resistance to the deposition of plasma...
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5439740 |
Composite fibers having a diamond surface
The present invention relates to composite fibers having a diamond surface which can be produced using a substrate such as graphite, or other non-diamond inorganic fiber. These substrates produced...
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5403808 |
Sorbents for flue gas desulfurization
The subject invention relates to a process for the production of a sorbent for SO2 comprising mixing a source of Ca3 SiO5 admixed with about 3 % of a compound such as CaSO4 2 H2 O that facilitates...
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5400784 |
Slowly penetrating inter-fascicular nerve cuff electrode and method of using
A self-curling sheet of a non-conductive material is biased to curl into a tight cylinder. Inwardly extending conductive members are disposed on the surface of the sheet forming the inside of the...
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5394883 |
Multiple thin film sensor system
A plurality of flow sensors are fabricated using thin film deposition techniques on a single substrate. The deposition is performed to provide the proper physical relationship of the individual...
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5377148 |
Apparatus and method to test random access memories for a plurality of possible types of faults
The present invention provides a test method of the complexity of 7n to test RAM devices, where n is the number of bits. This method tests all cell stuck-at-1/0 faults, state transition 1-to-0 and...
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5374712 |
Imidazopyridinium compound and processes for isolating, identifying, and chemically synthesizing same
The present invention is directed to a novel imidazo [4,5b] pyridinium molecule composed of a lysine and an arginine residue crosslinked with a pentose sugar. The novel imidazo [4,5b] pyridinium...
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5366493 |
Double helix functional stimulation electrode
First and second electrical wires (10), (12) are wrapped helically around a polyprolene core (22). Along a single helical portion (A), a sheath (24) is placed over the spiral wound wires and core....
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5358741 |
Composite fibers having a diamond surface
The present invention relates to composite fibers having a diamond surface which can be produced using a substrate such as graphite, or other non-diamond inorganic fiber. These substrates produced...
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5352485 |
Synthesis of metal oxide thin films
Iron and titanium oxide thin films are deposited onto functionalized self-assembled monolayers (SAMs) which are bonded to silicon or glass substrates. The resulting oxide thin films have ordered,...
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5324322 |
Thin film implantable electrode and method of manufacture
A sheet (30) of polymeric material defines a cuff portion (A), a contact portion (B), and an interconnecting elongated lead portion (C). Using physical vapor deposition (PVD), chemical vapor...
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5300422 |
Screening method for controlling agranulocytosis
A screening method for detecting the vulnerability of patients on clozapine therapy to developing agranulocytosis which comprises establishing the concentration of N-desmethylclozapine in the blood...
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5298654 |
Method for producing coprecipitated multicomponent oxide powder precursors
Guanidine oxalate is used as a precipitating agent in the coprecipitation of multicomponent oxide powder precursors. A solution of a soluble inorganic salt is combined with a solution of guanidine...
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5266409 |
Hydrogenated carbon compositions
A composition of matter having an atomic density between that of pure diamond and at least 0.18 g-atoms per cubic centimeter and the formula: C1-z-w Siz Aw [H1-x Fx ]ywhere: 0≤z+w≤0.15, 0≤w...
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5252314 |
Method for producing coprecipitated multicomponent oxide powder precursors using guanidine oxalate as precipitating agent
Guanidine oxalate is used as a precipitating agent in the coprecipitation of multicomponent oxide powder precursors. A solution of a soluble inorganic salt is combined with a solution of guanidine...
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5251636 |
Multiple thin film sensor system
A plurality of flow sensors are fabricated using thin film deposition techniques on a single substrate. The deposition is performed to provide the proper physical relationship of the individual...
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5233024 |
Anti-idiotypic monoclonal antibodies for mucoid Pseudomonas aeruginosa, their preparation and use
An anti-idiotypic monoclonal antibody, which induces production of mucoid exopolysaccharide-specific antibodies which are opsonic for mucoid Pseudemonas aeruginosa. The anti-idiotypic monoclonal...
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5221679 |
Method of treating therapy resistant schizophrenia with melperone (R-fluoro-Y-methyl-peperidino-butyrophrenone)
The invention relates to a method of treating therapy-resistant schizophrenia which includes administering a therapeutically effective amount of melperone...
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