Patents and Patent Applications from California Institute of Technology


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US20170348147 IMPLANTABLE OXYGEN GENERATOR AND TRANSPORTER  
An implantable medical device is described. The implantable medical device includes a small molecule generator, a small molecule diffusor, and a cannula that connects the two. The small molecule...
US20170347888 BRAIN-MACHINE INTERFACE BASED ON PHOTONIC NEURAL PROBE ARRAYS  
Method and apparatus for illuminating and imaging tissue is provided. In one version, the method includes illuminating a volume of a tissue with photons from a three-dimensional array of optical...
9834439 Biomolecular self-assembly  
The present invention relates generally to programming of biomolecular self-assembly pathways and related methods and constructs for self-assembly of prescribed two and three-dimensional structures.
US20170346347 Laser Wireless Power Transfer System With Active And Passive Safety Measures  
A wireless laser power transfer system includes, in part, a transmitter and a receiver that form a wireless link. The transmitter, includes, in part, a first communication system, at least a first...
US20170342455 METHODS AND APPARATUS FOR ASSAYS OF BACTERIAL SPORES  
Described herein are methods and apparatus for assays of bacterial spores. In particular, methods and apparatus for lateral flow immunoassay for bacterial spore detection and quantification,...
9831957 Self-equalizing photo detector  
A self-equalizing photo-detector (SEPD) includes, in part, a multitude of optical splitters and photo detectors, and at least one optical delay element. The first optical splitter splits an...
9831951 Optically balanced opto-electrical oscillator  
An opto-electrical oscillator includes, in part, first and second optical phase modulators, a coupler, an optical-to-electrical signal conversion circuit, and a control circuit. The first optical...
9831873 Method and apparatus for simultaneous processing of multiple functions  
Electronic logic gates that operate using N logic state levels, where N is greater than 2, and methods of operating such gates. The electronic logic gates operate according to truth tables. At...
9831372 P-compensated and P-doped superlattice infrared detectors  
Barrier infrared detectors configured to operate in the long-wave (LW) infrared regime are provided. The barrier infrared detector systems may be configured as pin, pbp, barrier and double...
9831043 Electrochemical energy storage systems and methods  
A three-dimensional electrode array for use in electrochemical cells, fuel cells, capacitors, supercapacitors, flow batteries, metal-air batteries and semi-solid batteries.
9829695 Array level Fourier ptychographic imaging  
In one aspect an imaging system includes: an illumination system including an array of light sources; an optical system including one or more lens arrays, each of the lens arrays including an...
US20170336340 IN SITU CHEMICAL SENSING ELECTRODE RECONDITIONING  
A cycle of positive and negative voltage pulses applied to an electrode sensor removes passivation of an electrode surface. The conditioned sensors have improved sensitivity to concentrations for...
9825193 Photon and carrier management design for nonplanar thin-film copper indium gallium diselenide photovoltaics  
Photovoltaic structures are disclosed. The structures can comprise randomly or periodically structured layers, a dielectric layer to reduce back diffusion of charge carriers, and a metallic layer...
9822356 Fluidic devices and systems for sample preparation or autonomous analysis  
The present invention relates to fluidic devices for preparing, processing, storing, preserving, and/or analyzing samples. In particular, the devices and related systems and methods allow for...
9821297 Methods to produce molecular sieves with LTA topology and compositions derived therefrom  
The present disclosure is directed to processing for preparing crystalline pure-silica and heteroatom-substituted LTA frameworks in fluoride media using a simple organic structure-directing agent...
9819151 High-coherence semiconductor light sources  
A laser resonator includes an active material, which amplifies light associated with an optical gain of the resonator, and passive materials disposed in proximity with the active material. The...
9817250 Optical modulator including nanostructure  
An optical modulator includes a plurality of nanostructures, each nanostructure of the plurality of nanostructures having a refractive index that is variable; a first insulation layer having a...
9816812 Systems and methods for automated vessel navigation using sea state prediction  
Systems and methods for sea state prediction and autonomous navigation in accordance with embodiments of the invention are disclosed. One embodiment of the invention includes a method of...
9816126 Method and apparatus for detecting and quantifying bacterial spores on a surface  
A method and an apparatus for detecting and quantifying bacterial spores on a surface. In accordance with the method: a matrix including lanthanide ions is provided on the surface containing the...
9815712 High capacity perchlorate-selective resins from hyperbranched macromolecules  
A resin is provided for selectively binding to perchloride and related anions (e.g., TcO4−, ReO4− and I−) in aqueous solution. The resin may take the form of microparticles or beads. The beads are...
9815694 Catalytic ammonia synthesis by transition metal molecular complexes  
This invention relates to molecular catalysts and chemical reactions utilizing the same, and particularly to catalysts and catalytic methods for reduction of molecular nitrogen. The molecular...
US20170324162 Modular Optical Phased Array  
A phased array includes, in part, M×N photonic chips each of which includes, in part, an array of transmitters and an array of receivers. At least one of M and/or N is an integer greater than one....
US20170322207 LABEL-FREE DETECTION OF NANOPARTICLES AND BIOLOGICAL MOLECULES USING MICROTOROID OPTICAL RESONATIORS  
Systems and methods are provided for detecting one or more particles such as individual unlabeled molecules or single nanoparticles. In examples described herein, optical energy is introduced into...
US20170320792 TANDEM TRANSFER HYDROGENATION AND OLIGOMERIZATION FOR HYDROCARBON PRODUCTION  
A method for coupling an alkane with an alkene using a hydrogen transfer catalyst and an alkene dimerization catalyst to form one or more higher molecular weight hydrocarbons.
9809607 Silylation of aromatic heterocycles by earth abundant transition-metal-free catalysts  
The present invention describes chemical systems and methods for silylating aromatic organic substrates, said system or method comprising or consisting essentially of a mixture of (a) at least one...
9809528 Production of alpha-hydroxy carboxylic acids and esters from higher sugars using tandem catalyst systems  
The present disclosure is directed to methods and composition used in the preparation of alpha-hydroxy carboxylic acids and esters from higher sugars using a tandem catalyst system comprising...
9808798 Fluidic devices for biospecimen preservation  
The present invention relates to fluidic devices for preparing, processing, storing, preserving, and/or analyzing samples. In particular, the devices and related systems and methods allow for...
US20170318407 Systems and Methods for Generating Spatial Sound Information Relevant to Real-World Environments  
Spatial exploration systems and methods of spatial exploration utilizing spatial sound in accordance with various embodiments of the invention are disclosed. In one embodiment, a spatial...
US20170317654 SPATIAL POWER COMBINING MECHANISM (SPCM) FOR THE GENERATION AND AMPLIFICATION OF ELECTROMAGNETIC RADIATION  
A Spatial Power Combining Amplifier (SPCA) exhibiting a new concept for the amplification of coherent (e.g., microwave) radiation. A general description of the SPCA a power analysis at various...
US20170315178 SYSTEMS AND METHODS FOR DETECTING ABNORMALITIES IN ELECTRICAL AND ELECTROCHEMICAL ENERGY UNITS  
A method for abnormality detection in an energy unit includes passively detecting an abnormality in an energy unit by detecting electromagnetic radiation generated by the abnormality, the energy...
US20170315067 BACKSCATTER IMAGING SYSTEMS AND METHODS WITH HELICAL MOTION  
Backscatter imaging systems and methods that involve moving an emitter and a broad spectrum detector in helical motion along a medium being imaged while the emitter emits substantially...
US20170315060 COMPOSITIONS AND METHODS FOR LEUKOCYTE DIFFERENTIAL COUNTING  
The present invention provide compositions and methods for classifying leukocytes in a leukocyte population using fluorescence detection. The methods include contacting a leukocyte population in a...
9803237 Slip-induced compartmentalization  
The present invention relates to fluidic devices for compartmentalizing samples. In particular, the devices and related systems and methods allow for compartmentalization by using one or more...
US20170309918 THREE-DIMENSIONAL ION TRANSPORT NETWORKS AND CURRENT COLLECTORS FOR ELECTROCHEMICAL CELLS  
Provided herein are three-dimensional ion transport networks and current collectors for electrodes of electrochemical cells. Exemplary electrodes include interconnected layers and channels...
9800643 Coding for real-time streaming under packet erasures  
A computer-based real-time streaming system under packet erasures wherein created messages can be decoded within a fixed delay form their creation is presented. Various code construction methods...
9799785 Unipolar barrier dual-band infrared detectors  
Dual-band barrier infrared detectors having structures configured to reduce spectral crosstalk between spectral bands and/or enhance quantum efficiency, and methods of their manufacture are...
US20170302048 STABILIZED NON-RECIPROCAL FIBER-RING BRILLOUIN LASER SOURCE  
A stabilized laser source includes a fiber-ring Brillouin laser that incorporates a circulator for non-reciprocal operation and for launching of a pump optical signal. Most of the pump optical...
US20170299854 ARRAY LEVEL FOURIER PTYCHOGRAPHIC IMAGING  
In one aspect an imaging system includes: an illumination system including an array of light sources; an optical system including one or more lens arrays, each of the lens arrays including an...
US20170299483 DEVICES AND METHODS FOR PREPARING BIOLOGICAL SAMPLES  
Devices and methods for biological sample preparation are provided herein. Components of such devices include a plurality of plungers that can be actuated for metering and/or mixing one or more...
US20170298709 HIGH PRESSURE HIGH FLOW DIGITAL VALVE WITH LOCKING POPPETS AND BACKFLOW PREVENTION  
A valve that allows control of each of one or more flow paths using one actuator is presented. Rotary motion of a motor is transformed into linear motion using a roller screw mechanism. The travel...
US20170298425 THERMAL BIOSWITCHES AND RELATED GENETIC CIRCUITS, VECTORS, CELLS, COMPOSITIONS, METHODS AND SYSTEMS  
Temperature sensitive transcriptional bioswitches and related genetic circuits and in particular bandpass and/or multiplex genetic circuits, vectors, cells, compositions methods and systems are...
US20170296665 TARGETED NANOPARTICLES  
Described herein are carrier nanoparticles comprising a polymer containing a polyol coupled to a polymer containing a nitroboronic boronic acid and a linkage cleavable under reducing conditions,...
9791372 Multiplexing and quantification in PCR with reduced hardware and requirements  
Methods and algorithms for a multiplexed single detection channel amplification process and quantification of generated amplicons is presented. Various mathematical approaches for quantifying and...
9791321 340 GHz multipixel transceiver  
A multi-pixel terahertz transceiver is constructed using a stack of semiconductor layers that communicate using vias defined within the semiconductor layers. By using a stack of semiconductor...
9791032 Method for manufacturing bulk metallic glass-based strain wave gear components  
Systems and methods in accordance with embodiments of the invention implement bulk metallic glass-based strain wave gears and strain wave gear components. In one embodiment, a method of...
US20170292958 METHODS FOR PROTEOMIC PROFILING USING NON-NATURAL AMINO ACIDS  
The invention provides methods, reagents and systems for incorporating non-natural amino acids into proteins, preferably in vivo, using the endogenous protein synthesis machinery of an organism....
9783877 Systems and methods for implementing bulk metallic glass-based macroscale compliant mechanisms  
Systems and methods in accordance with embodiments of the invention implement bulk metallic glass-based macroscale compliant mechanisms. In one embodiment, a bulk metallic glass-based macroscale...
9783784 Methods for establishing and improving the survival of a population of pancreatic progenitor or stem cells  
In some embodiments, methods for improving the survival of pancreatic β-cell progenitors in culture are provided. Such methods may include contacting a population of pancreatic progenitor cells...
9783594 Human immunodeficiency virus neutralizing antibodies and methods of use thereof  
The invention provides broadly neutralizing antibodies directed to epitopes of Human Immunodeficiency Virus, or HIV. The invention further provides compositions containing HIV antibodies used for...
9782759 Methods for producing crystalline microporous solids with IWV topology and compositions derived from the same  
This disclosure relates to new crystalline microporous solids (including silicate- and aluminosilicate-based solids), the compositions comprising 8 and 10 membered inorganic rings, particularly...