Patents and Patent Applications from California Institute of Technology


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10003278 Active CMOS recovery units for wireless power transmission  
A rectifying circuit includes, in part, first and second NMOS transistors, an impedance matching network, and an RF block circuit. The source and gate terminals of the first NMOS transistor...
US20180164276 SENSING AND ACTUATION OF BIOLOGICAL FUNCTION USING ADDRESSABLE TRANSMITTERS OPERATED AS MAGNETIC SPINS  
Methods and apparatuses for sensing biological functions are disclosed. Sensors can be implanted in an organ, such as the brain, and a magnetic field gradient applied to the biological tissue. The...
US20180162893 UTILITY OF NEMATODE SMALL MOLECULES  
The present invention relates to methods of treating immune disorders and/or inflammation using certain modulator compounds. In one embodiment, the present invention provides a method of treating...
9998658 Variable-illumination fourier ptychographic imaging devices, systems, and methods  
Certain aspects pertain to Fourier ptychographic imaging systems, devices, and methods such as, for example, high NA Fourier ptychographic imaging systems and reflective-mode NA Fourier...
9995930 Focusing device comprising a plurality of scatterers and beam scanner and scope device  
A focusing device includes a substrate and a plurality of scatterers provided at both sides of the substrate. The scatterers on the both sides of the focusing device may correct geometric...
9995859 Conformal optical metasurfaces  
Structures for scattering light at multiple wavelengths are disclosed. Scattering elements are fabricated with different geometric dimensions and arrangements, to scatter or focus light at the the...
9994867 Method of targeting gene delivery using viral vectors  
Methods and compositions are provided for delivering a polynucleotide encoding a gene of interest to a target cell using a virus. The virus envelope comprises a cell-specific binding determinant...
9993185 Plasmonics nanostructures for multiplexing implantable sensors  
Methods and systems for nanopillar sensors are described. Nanopillars can be defined on a substrate, and metal deposited on the nanopillars. A thermal treatment can reflow the metal on the...
9993149 Fourier ptychographic retinal imaging methods and systems  
Certain embodiments pertain to Fourier ptychographic retinal imaging methods and systems that focus on a retina of an eye to acquire a sequence of raw retinal images, construct a full-resolution,...
US20180159516 HIGH-EFFICIENCY FREQUENCY DOUBLER WITH A COMPENSATED TRANSFORMER-BASED INPUT BALUN  
The disclosed embodiments relate to the design of a high-speed frequency doubler circuit. During operation, the circuit uses a transformer-based balun to convert a single-ended input signal into a...
US20180159139 Nanofibers Decorated with Nanoparticles and Methods of Their Manufacture  
Nanostructured materials, and methods and apparatus for their production are provided. Nanostructured materials comprise nanofibers having nanoparticles deposited along the outer surface thereof....
US20180155819 Layered Structures for the Protection of Molecules  
A multilayer structure can selectively bind certain molecules, due to reentrant spaces having an appropriate size. The multilayers can be fabricated by alternating layers of two different...
US20180155271 SILYLATIONS OF AROMATIC SUBSTRATES WITH BASE-ACTIVATED ORGANOSILANES  
The present disclosure describes methods for silylating aromatic organic substrates, and associated chemical systems, said methods comprising or consisting essentially of contacting the aromatic...
US20180154342 PROCESSES FOR PREPARING ZINCOALUMINOSILICATES WITH AEI, CHA, AND GME TOPOLOGIES AND COMPOSITIONS DERIVED THEREFROM  
The present disclosure is directed to methods of producing zincoaluminosilicate structures with AEI, CHA, and GME topologies using organic structure directing agents (OSDAs), and the compositions...
9991677 Index-coupled distributed-feedback semiconductor quantum cascade lasers fabricated without epitaxial regrowth  
Quantum cascade (QC) lasers and methods of fabricating such QC lasers are provided. The QC lasers incorporate a DFB grating without requiring the use of relying on epitaxial regrowth processes....
9991492 Separator enclosures for electrodes and electrochemical cells  
The disclosure provides electrochemical cells including a separator enclosure which encloses at least a portion of a positive or negative electrode. In an embodiment, the separator generates a...
9989680 Controllable planar optical focusing system  
An optical device has a first metasurface. A high-contrast pattern of the first metasurface is operable for modifying, over a first phase profile, a phase front of an incident light beam. A second...
9988653 Method and apparatus for CO2 sequestration  
Processes, methods, and apparatus for carbon sequestration utilizing catalysis schemes configured to provide high concentrations of hydrated CO2 in proximity with a sequestration agent are...
9987609 Multiplexed surface enhanced Raman sensors for early disease detection and in-situ bacterial monitoring  
Methods and systems for nanopillar sensors are described. Nanopillars can be defined on a substrate, and metal deposited on the nanopillars. A thermal treatment can reflow the metal on the...
9986934 Microwave radar sensor modules  
Systems and methods for detecting biometrics using microwave radar sensor modules are disclosed. Integrated microwave sensor modules can include a transmitter unit configured to generate at least...
US20180152204 Balanced Reed-Solomon Codes  
Balanced Reed-Solomon codes in accordance with embodiments of the invention enable balanced load in distributed storage systems. One embodiment includes a storage controller, wherein the storage...
US20180148745 HEMOPROTEIN CATALYSTS FOR IMPROVED ENANTIOSELECTIVE ENZYMATIC SYNTHESIS OF TICAGRELOR  
The present invention provides methods by which trans-(1R,2S)-2-(3,4-difluorophenyl)-cyclopropylamine and related cyclopropane compounds are prepared using synthetic strategies that include a...
9983808 NAND flash reliability with rank modulation  
The reliability of NAND flash memory decreases rapidly as density increases, preventing the wide adoptions of flash-based storage systems. A novel data representation scheme named rank modulation...
9983397 Aperture scanning fourier ptychographic imaging  
Certain aspects pertain to aperture-scanning Fourier ptychographic imaging devices comprising an aperture scanner that can generate an aperture at different locations at an intermediate plane of...
9981389 Robotics platforms incorporating manipulators having common joint designs  
Manipulators in accordance with various embodiments of the invention can be utilized to implement statically stable robots capable of both dexterous manipulation and versatile mobility....
US20180142307 RECORDING AND MAPPING LINEAGE INFORMATION AND MOLECULAR EVENTS IN INDIVIDUAL CELLS  
Methods and systems for recording and mapping lineage information and molecular events in individual cells are provided. Molecular changes, which may result from random or specific molecular...
9980388 Biocompatible ribbon cable with narrow folded section  
A biocompatible, micro-fabricated ribbon cable is described in which at least one set of conductors diverges laterally into a bypass wing that forms an aperture through the ribbon cable. The...
9976912 Broadband, common-path, interferometric wavefront sensor  
Hybrid sensors comprising Shack-Hartmann Wavefront Sensor (S-HWFS) and Zernike Wavefront Sensor (Z-WFS) capabilities are presented. The hybrid sensor includes a Z-WFS optically arranged in-line...
9976220 Protecting the surface of a light absorber in a photoanode  
A photoanode includes a passivation layer on a light absorber. The passivation layer is more resistant to corrosion than the light absorber. The photoanode includes a surface modifying layer that...
US20180137991 ELECTROCHEMICAL ENERGY STORAGE SYSTEMS AND METHODS  
A three-dimensional electrode array for use in electrochemical cells, fuel cells, capacitors, supercapacitors, flow batteries, metal-air batteries and semi-solid batteries.
US20180134664 DNA2 INHIBITORS FOR CANCER TREATMENT  
Disclosed herein, inter alia, are compositions and methods for inhibiting DNA2.
9971136 Method and device to achieve spatially confined photointeraction at the focal volume of a microscope  
The invention relates to a method and a system to achieve spatially (e.g. three-dimensionally) confined photomodulation at the focal volume (50) in a ample (55) mounted in a microscope system,...
9969858 Metalloinsertor conjugates  
A composition including a metalloinsertor conjugate that specifically targets mismatch repair (MMR)-deficient cells includes a complex represented by Formula I. Mm+(L1)(L2)(L3)(L4)(L5) Formula I...
9969828 Co-supported catalysts for the tandem trimerization and polymerization of ethylene to produce linear low density polyethylene  
Linear low density polyethylene (LLDPE) is produced from an ethylene-only feed over a tandem catalyst system consisting of a phenoxy-imine titanium trimerization catalyst and a silylene-linked...
US20180128683 Monolithic Assembly of Reflective Spatial Heterodyne Spectrometer  
Novel monolithic cyclical reflective spatial heterodyne spectrometers (CRSHS) are presented. Monolithic CRSHS in accordance with the invention have a single frame wherein a flat mirror, roof...
US20180127539 FUNCTIONALIZED LINEAR AND CYCLIC POLYOLEFINS  
This invention relates to methods and compositions for preparing linear and cyclic polyolefins. More particularly, the invention relates to methods and compositions for preparing functionalized...
US20180127093 Positioning of In-Situ Methane Sensor on a Vertical Take-Off and Landing (VTOL) Unmanned Aerial System (UAS)  
Unmanned Aerial Systems (UAS) for use in the detection, localization, and quantification of gas leaks are provided. More specifically the use of an in-situ sensor mounted to a UAS such that the...
US20180126364 METHODS TO PRODUCE ZEOLITES WITH THE GME TOPOLOGY AND COMPOSITIONS DERIVED THEREFROM  
The present disclosure is directed to producing zeolite structures with GME topologies using organic structure directing agents (OSDAs) comprising a piperidinium cation, and the compositions and...
9966443 Nanopillar field-effect and junction transistors with functionalized gate and base electrodes  
Systems and methods for molecular sensing are described. Molecular sensors are described which are based on field-effect or bipolar junction transistors. These transistors have a nanopillar with a...
9964755 Optimized actuators for ultra-thin mirrors  
A method and apparatus for correcting error modes of a deformable mirror, including selecting or targeting one or more target error modes of a deformable mirror; and designing a pattern and/or...
9963720 Alkane oxidation by modified hydroxylases  
This invention relates to modified hydroxylases. The invention further relates to cells expressing such modified hydroxylases and methods of producing hydroxylated alkanes by contacting a suitable...
9963717 Method for expression of small RNA molecules within a cell  
The invention provides methods and compositions for the expression of small RNA molecules within a cell using a lentiviral vector. The methods can be used to express doubles stranded RNA...
US20180123699 OPTICAL SPARSE PHASED ARRAY RECEIVER  
A sparse optical phased array transmitter/receiver includes, in part, a multitude of transmitting/receiving elements that are sparsely positioned. Accordingly, the transmitting/receiving elements...
US20180121832 WEIGHT GENERATION IN MACHINE LEARNING  
Technologies are generally described for systems, devices and methods relating to a machine learning environment. In some examples, a processor may identify a training distribution of a training...
US20180119259 SYSTEMS AND METHODS FOR SHAPING SHEET MATERIALS THAT INCLUDE METALLIC GLASS-BASED MATERIALS  
Systems and methods in accordance with embodiments of the invention advantageously shape sheet materials that include metallic glass-based materials. In one embodiment, a method of shaping a sheet...
US20180118706 Synthetic Route To Anhydroryanodol, Ryanodol And Structural Analogues  
This disclosure is related to methods for producing anhydroryanodol, ryanodol, or analogues thereof and novel compounds prepared thereby.
9960238 Nanopillar field-effect and junction transistors with functionalized gate and base electrodes  
Systems and methods for molecular sensing are described. Molecular sensors are described which are based on field-effect or bipolar junction transistors. These transistors have a nanopillar with a...
9958707 Systems and methods for implementing electrically tunable metasurfaces  
Systems and methods in accordance with embodiments of the invention implement electrically tunable metasurfaces. In one embodiment, an electrically tunable metasurface reflectarray includes: a...
9958582 Image sensor including nanostructure color filter  
An image sensor includes an optical sensor layer including a plurality of light-sensitive cells configured to sense light to generate electrical signals, and a color filter array layer disposed on...
9958510 Integrated magnetic spectrometer for multiplexed biosensing  
A magnetic spectrometer is integrated in a semiconductor substrate and provides high sensitivity without using an external magnet field. The spectrometer includes one or more highly stable on-chip...