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Patents and Patent Applications from California Institute of Technology


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US20130097164 SYSTEMS AND METHODS FOR DISTRIBUTED DATA ANNOTATION  
Systems and methods for distributed data annotation in accordance embodiments of the invention are disclosed. In one embodiment of the invention, a distributed data annotation server system...
US20130092549 PROTON EXCHANGE MEMBRANE ELECTROLYSIS USING WATER VAPOR AS A FEEDSTOCK  
A light-driven electrolytic cell that uses water vapor as the feedstock and that has no wires or connections whatsoever to an external electrical power source of any kind. In one embodiment, the...
US20130091591 ARTERY- AND VEIN-SPECIFIC PROTEINS AND USES THEREFOR  
Arterial and venous endothelial cells are molecularly distinct from the earliest stages of angiogenesis. This distinction is revealed by expression on arterial cells of a transmembrane ligand,...
US20130090319 METALLOINSERTOR COMPLEXES TARGETED TO DNA MISMATCHES  
A composition including a Rh or Ru metalloinsertor complex specifically targets mismatch repair (MMR)-deficient cells. Selective cytotoxicity is induced in MMR-deficient cells upon uptake of the...
D679646 Descent stage for mars rover  
8416400 Wavefront imaging sensor  
Embodiments of the present invention relate to a wavefront imaging sensor (WIS) comprising an aperture layer having an aperture, a light detector having a surface and a transparent layer between...
8415646 Production of MeV micro beams of protons for medical applications  
A proton beam guidance apparatus and a method of providing proton beams having sub-micron beam width and MeV energies. The apparatus is a structure having an enclosed channel that can reflect or...
8414911 Photochemical therapy to affect mechanical and/or chemical properties of body tissue  
The disclosure concerns altering the mechanical and/or chemical property of a body tissue, particularly an ocular tissue. In specific cases, it concerns altering or stabilizing the shape of the...
8414785 Methods for fabrication of microfluidic systems on printed circuit boards  
Methods for fabrication of microfluidic systems on printed circuit boards (PCB) are described. The PCB contains layers of insulating material and a layer or layers of metal buried within layers of...
US20130085398 BRAIN-MACHINE INTERFACE BASED ON PHOTONIC NEURAL PROBE ARRAYS  
Method and apparatus for illuminating and imaging tissue is provided. In one version, the method includes illuminating a volume of a tissue with photons from a three-dimensional array of optical...
8413019 Computer-implemented method for correcting transmission errors using linear programming  
A computer-implemented method for correcting transmission errors. According to the method, a transmitted vector corrupted by error can be recovered solving a linear program. The method has...
8411282 On-chip phase microscope/beam profiler based on differential interference contrast and/or surface plasmon assisted interference  
A differential interference contrast (DIC) determination device and method utilizes an illumination source, a layer having a pair of two apertures that receive illumination from the illumination...
US20130080861 ERASURE CODING SCHEME FOR DEADLINES  
Error correction coding for streaming communication is provided. A streaming problem is modeled as a non-multicast network problem with a nested receiver structure. Each packet in the streaming...
US20130075487 Atmospheric Condensate Collector and Electrospray Source  
An atmospheric condensate collector and electrospray source apparatus. The apparatus has a cooler having a surface with a sharp point. The cooler generates a condensate from ambient atmosphere...
US20130074898 THERMOELECTRIC COOLING SYSTEM UTILIZING THE THOMSON EFFECT  
Thermoelectric cooling systems are disclosed that utilize the Thomson effect. The disclosed systems can be used, for example, in cryogenic applications. In one aspect, a system is provided for...
US20130074313 Multilayered Cellular Metallic Glass Structures and Methods of Preparing the Same  
Multi-layered cellular metallic glass structures and methods of preparing the same are provided. In one embodiment, the cellular metallic glass structure includes at least one patterned metallic...
US20130069665 USING A FIELD EFFECT DEVICE FOR IDENTIFYING TRANSLOCATING CHARGE-TAGGED MOLECULES IN A NANOPORE SEQUENCING DEVICE  
A detector apparatus includes a field-effect transistor configured to undergo a change in amplitude of a source-to-drain current when at least a portion of a charge-tagged molecule translocates...
US20130068623 TRANSLOCATION AND NUCLEOTIDE READING MECHANISMS FOR SEQUENCING NANODEVICES  
By driving molecules electrophoretically through a nanopore, single molecule detection can be achieved. To enhance translocational control, functionalized and non-functionalized electrodes are...
US20130068527 SYSTEMS AND METHODS FOR GRAVITY-INDEPENDENT GRIPPING AND DRILLING  
Systems and methods for gravity independent gripping and drilling are described. The gripping device can also comprise a drill or sampling devices for drilling and/or sampling in microgravity...
8401793 High resolution wind measurements for offshore wind energy development  
A method, apparatus, system, article of manufacture, and computer readable storage medium provide the ability to measure wind. Data at a first resolution (i.e., low resolution data) is collected by...
8397549 System for formation of highly nonlinear pulses  
A system supporting the formation and propagation of tunable highly nonlinear pulses using granular chains composed of non-spherical granular systems. Such a system may be used to support the...
US20130066029 MULTI-METALLIC ORGANOMETALLIC COMPLEXES, AND RELATED POLYMERS, COMPOSITIONS, METHODS AND SYSTEMS  
Multi-metallic organometallic complexes that allow performance of olefin based reaction and in particular polymerization of olefins to produce polyolefin polymers, and related methods and systems...
US20130064859 COMBINATORIAL VITAMIN D AND PROBIOTIC THERAPY FOR INFLAMMATORY BOWEL DISEASE  
A method of increasing the percentage of mouse and human Tregs is provided comprising providing B.fragilis or PSA and vitamin D or vitamin D metabolite to said mouse or human. Also, a method for...
US20130062134 TERRAIN TRAVERSING DEVICE HAVING A WHEEL WITH MICROHOOKS  
A terrain traversing device includes an annular rotor element with a plurality of co-planar microspine hooks arranged on the periphery of the annular rotor element. Each microspine hook has an...
8395773 Optical devices and methods for measuring samples  
Optical devices and methods for measuring samples while minimizing stray light are described. Such methods and devices are applicable to multiple fluid chambers with multiple sources as an...
8395243 Surface passivation by quantum exclusion using multiple layers  
A semiconductor device has a multilayer doping to provide improved passivation by quantum exclusion. The multilayer doping includes a plurality M of doped layers, where M is an integer greater than...
8394590 Capture agents and related methods and systems for detecting and/or sorting targets  
Polynucleotide-encoded capture agents for target detection and in particular modular polynucleotide-capture agents comprising a target binding component, a scaffold component and an encoding...
8394330 Conductive organic sensors, arrays and methods of use  
The present invention provides a class of sensors prepared from regions of conducting organic materials and conducting materials that show an increase sensitivity detection limit for amines. The...
US20130058533 IMAGE RECONSTRUCTION BY POSITION AND MOTION TRACKING  
A system, method, and apparatus provide the ability to reconstruct an image from an object. A hand-held image acquisition device is configured to acquire local image information from a physical...
8392869 Systems and methods for circuit lifetime evaluation  
Systems and methods for estimating the lifetime of an electrical system in accordance with embodiments of the invention are disclosed. One embodiment of the invention includes iteratively...
8391426 Broadband phase synthesis network with self-healing capability  
A phase synthesis network having self healing capability. The phase synthesis network includes two phase rotators that receive I and Q input LO signals, that receive a digital control signal, and...
8388822 Method and apparatus for analysis and sorting of polynucleotides based on size  
The invention relates to a microfabricated device and methods of using the device for analyzing and sorting polynucleotide molecules by size.
8387465 Carbon nanotube vacuum gauges with wide-dynamic range and processes thereof  
A miniature thermal conductivity gauge employs a carbon single-walled-nanotube. The gauge operates on the principle of thermal exchange between the voltage-biased nanotube and the surrounding gas...
US20130052732 DNA-DAMAGE-INDUCED PROTEOLYSIS  
The present application provides methods for identifying compounds for inhibiting DNA damage-induced Htt proteolysis, and methods and compositions for protecting cells from DNA damage-induced...
US20130048152 Bulk Nickel-Based Chromium and Phosphorous Bearing Metallic Glasses  
Ni-based Cr- and P-bearing alloys that can from centimeter-thick amorphous articles are provided. Within the family of alloys, millimeter-thick bulk-glassy articles can undergo macroscopic plastic...
8386370 Method and apparatus for providing a market environment  
The system provides two-sided local markets that enable local and/or intermittent resource allocation through a market model. The system provides a method for defining goods, services or assets are...
8383425 Method and compositions for the detection of protein glycosylation  
The invention provides methods and compositions for the rapid and sensitive detection of post-translationally modified proteins, and particularly of those with post-translational glycosylations....
8382896 High throughput screening of crystallization materials  
High throughput screening of crystallization of a target material is accomplished by simultaneously introducing a solution of the target material into a plurality of chambers of a microfabricated...
US20130044788 SCANNING MEASUREMENT OF SEEBECK COEFFICIENT OF A HEATED SAMPLE  
A novel scanning Seebeck coefficient measurement technique is disclosed utilizing a cold scanning thermocouple probe tip on heated bulk and thin film samples. The system measures variations in the...
US20130043143 DEVICE FOR DETECTING GASES AND/OR VOLATILE ORGANIC COMPOUNDS (VOC)  
The present invention concerns a device for detecting gases or volatile organic compounds (VOC) comprising an electrically conducting or semiconducting zone f unctionalized with an organic film...
8378758 Parametric feedback oscillators  
A parametric feedback oscillator includes a resonator which has at least one transduction element and at least one electromechanical resonating element. The resonator is configured to accept as...
8378732 Octave-range, watt-level, fully-integrated CMOS switching power mixer array for linearization and back-off-efficiency improvement  
Power mixer arrays for providing watt-level power in mobile systems. In one embodiment, a fully-integrated octave-range CMOS power mixer that occupies only 2.6 mm2 using a 130 nm semiconductor...
8378669 Frequency-shift CMOS magnetic biosensor array with single bead sensitivity and no external magnet  
According to one aspect, an integrated magnetic particle measurement device for detecting a presence or absence of magnetic particles in a sample volume includes at least one sensor cell having a...
8377586 Fluoride ion electrochemical cell  
The present invention provides electrochemical cells capable of good electronic performance, particularly high specific energies, useful discharge rate capabilities and good cycle life....
US20130041636 METHODS AND SYSTEMS FOR COMPARING VERTICAL AXIS TURBINE ARRAYS AND PROVIDING CONFIGURATIONS THEREOF  
A method for providing potential flow elements including a vortex to capture rotation of a turbine, a dipole to capture a blockage effect of the turbine, a sink to capture extracted energy from...
US20130041319 Medicament Delivery Systems  
Described herein are systems, devices, and methods for the delivery of substances to, or the sampling of substances from, a patient using a portable and preferably implantable device. The...
US20130038482 MIXED LINEAR/SQUARE-ROOT ENCODED SINGLE SLOPE RAMP PROVIDES A FAST, LOW NOISE ANALOG TO DIGITAL CONVERTER WITH VERY HIGH LINEARITY FOR FOCAL PLANE ARRAYS  
An analog-to-digital converter (ADC) converts pixel voltages from a CMOS image into a digital output. A voltage ramp generator generates a voltage ramp that has a linear first portion and a...
8372390 Recombiant lentivirus comprising an E2 alphavirus glycoprotein that binds to DC-SIGN  
Methods and compositions are provided for delivery of a polynucleotide encoding a gene of interest, typically an antigen, to a dendritic cell (DC). The virus envelope comprises a DC-SIGN specific...
US20130033339 BIFURCATION-BASED ACOUSTIC SWITCH AND RECTIFIER  
A tunable frequency acoustic rectifier that is a granular crystal composed of a statically compressed one-dimensional array of particles in contact, containing a light mass defect near a boundary....
US20130032731 PRODUCTION OF MEV MICRO BEAMS OF PROTONS FOR MEDICAL APPLICATIONS  
A proton beam guidance apparatus and a method of providing proton beams having sub-micron beam width and MeV energies. The apparatus is a structure having an enclosed channel that can reflect or...