Patents and Patent Applications from California Institute of Technology


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9086955 Rank-modulation rewriting codes for flash memories  
Rank modulation has been recently proposed as a scheme for storing information in flash memories. Three improved aspects are disclosed. In one aspect the minimum push-up scheme, for storing data...
9086536 Talbot imaging devices and systems  
Talbot imaging systems comprising a Talbot element, a phase gradient generating device, a light detector, and a processor. The Talbot element repeats a Talbot image at a distance from the Talbot...
9085814 Bulk nickel-based chromium and phosphorous bearing metallic glasses  
Ni-based Cr- and P-bearing alloys that can from centimeter-thick amorphous articles are provided. Within the family of alloys, millimeter-thick bulk-glassy articles can undergo macroscopic plastic...
US20150197771 DOMAIN-SWAP T CELL RECEPTORS  
Disclosed herein are genetically engineered T cell receptors, and methods, vectors, and genetically engineered T cells related to genetically engineered T cell receptors.
9081252 Integrated two-dimensional planar optical phased array  
An optical phased array includes, in part, a multitude of optical signal emitters and a multitude of optical signal phase/delay elements each associated with and disposed between a different pair...
9080088 Granular crystal  
Granular crystals with one or more chains of particles are described. A geometry of at least one particle is chosen to provide highly nonlinear pulses having selected characteristics. Contact...
9078743 3-coil wireless power transfer system for eye implants  
A three-coil electromagnetic induction power transfer system is disclosed for epiretinal prostheses and other implants. A third, buffer coil is disposed between an external transmitting coil and a...
9074178 Alkane oxidation by modified hydroxylases  
This invention relates to modified hydroxylases. The invention further relates to cells expressing such modified hydroxylases and methods of producing hydroxylated alkanes by contacting a suitable...
US20150187718 THREE-DIMENSIONAL HIGH SURFACE AREA ELECTRODES  
Three dimensional high surface electrodes are described. The electrodes are fabricated by methods including the steps: designing the pillars; selecting a material for the formation of the pillars;...
US20150183633 Microfabricated Elastomeric Valve and Pump Systems  
A method of fabricating an elastomeric structure, comprising: forming a first elastomeric layer on top of a first micromachined mold, the first micromachined mold having a first raised protrusion...
9070733 Nanopillar field-effect and junction transistors with functionalized gate and base electrodes  
Systems and methods for molecular sensing are described. Molecular sensors are described which are based on field-effect or bipolar junction transistors. These transistors have a nanopillar with a...
9070268 Wireless sensor node for autonomous monitoring and alerts in remote environments  
A method, apparatus, system, and computer program products provides personal alert and tracking capabilities using one or more nodes. Each node includes radio transceiver chips operating at...
9067848 Nanostructured carbon materials for adsorption of methane and other gases  
Provided are methods for storing gases on porous adsorbents, methods for optimizing the storage of gases on porous adsorbents, methods of making porous adsorbents, and methods of gas storage of...
9067258 Forming of metallic glass by rapid capacitor discharge forging  
A forging apparatus and method of uniformly heating, rheologically softening, and thermoplastically forming metallic glasses rapidly into a net shape using a rapid capacitor discharge forming...
US20150180000 SEPARATOR ENCLOSURES FOR ELECTRODES AND ELECTROCHEMICAL CELLS  
The disclosure provides electrochemical cells including a separator enclosure which encloses at least a portion of a positive or negative electrode. In an embodiment, the separator generates a...
US20150177380 THREE-DIMENSIONAL TOMOGRAPHIC IMAGING CAMERA  
A detection apparatus and method for FMCW LIDAR employ signals whose frequencies are modified so that low-cost and low-speed photodetector arrays, such as CCD or CMOS cameras, can be employed for...
US20150175667 TARGETED GENE DELIVERY FOR DENDRITIC CELL VACCINATION  
Methods and compositions are provided for delivery of a polynucleotide encoding a gene of interest, typically an antigen, to a dendritic cell (DC). The virus envelope comprises a DC-SIGN specific...
US20150173593 ROTATIONAL SCANNING ENDOSCOPE  
A rotational scanning endoscope for rotationally scanning to capture a circumferential image
9065292 Methods and systems for charging electrochemical cells  
The invention provides systems and methods for charging an electrochemical device, such as a secondary electrochemical cell. Charging systems and methods of some embodiments provide charging...
9064667 Systems and methods for implementing robust carbon nanotube-based field emitters  
Systems and methods in accordance with embodiments of the invention implement carbon nanotube-based field emitters. In one embodiment, a method of fabricating a carbon nanotube field emitter...
9063002 Broadband, common-path, interferometric wavefront sensor  
Hybrid sensors comprising Shack-Hartmann Wavefront Sensor (S-HWFS) and Zernike Wavefront Sensor (Z-WFS) capabilities are presented. The hybrid sensor includes a Z-WFS optically arranged in-line...
US20150171398 ELECTROCHEMICAL SEPARATORS WITH INSERTED CONDUCTIVE LAYERS  
Disclosed are electrochemical cells including a composite separator capable of changing the performance of the cell by a) changing the internal electric field of the cell, b) activating lost...
US20150171326 SYSTEMS AND METHODS FOR INTEGRATING A SINGLE DNA MOLECULE INTO A MOLECULAR ELECTRONIC DEVICE  
The disclosed subject matter provides a techniques for precisely and/or functionally cutting carbon nanotubes, e.g., single walled carbon nanotubes (“SWNTs”) and integrating a single nucleic acid...
US20150167092 FRET-BASED ANALYTES DETECTION AND RELATED METHODS AND SYSTEMS  
FRET-based analytes detection and related methods and systems are described where a pair of FRET labeled primers and/or oligonucleotides are used that are specific for target sequences located at...
US20150166579 TRANSITION-METAL-FREE SILYLATION OF AROMATIC COMPOUNDS  
The present invention describes chemical systems and methods for silylating aromatic organic substrates, said system comprising a mixture of (a) at least one organosilane and (b) at least one...
9059557 Non-linear vertical-cavity surface-emitting laser equalization  
Technologies are generally described for implementing non-linear VCSEL equalization. In some examples, a rising edge tap parameter, a falling edge tap parameter, an equalization delay and a bias...
9059364 High thermoelectric performance by convergence of bands in IV-VI semiconductors, heavily doped PbTe, and alloys/nanocomposites  
The present invention teaches an effective mechanism for enhancing thermoelectric performance through additional conductive bands. Using heavily doped p-PbTe materials as an example, a...
9057780 Real-time and post-processed orbit determination and positioning  
Novel methods and systems for the accurate and efficient processing of real-time and latent global navigation satellite systems (GNSS) data are described. Such methods and systems can perform...
9057568 Temperature control devices and methods  
Temperature control devices and methods are described. The described temperature control devices and methods comprise optical emission and detection assemblies and can be used in PCR and qPCR...
9057070 Generation of Bacteriodes fragilis capsular polysaccharide A-only producing mutant strain  
Provided is an isolated B. fragilis bacterial cell producing a native capsular polysaccharide A (PSA), wherein the cell is incapable of producing capsular polysaccharides PSB, PSC, PSD, PSE, PSF,...
US20150160450 EMBEDDED PUPIL FUNCTION RECOVERY FOR FOURIER PTYCHOGRAPHIC IMAGING DEVICES  
Certain aspects pertain to Fourier ptychographic imaging systems, devices, and methods that implement an embedded pupil function recovery
US20150160384 FLAT RETROREFLECTORS  
A retroreflector device is described, which includes a lens component operable for focusing radiation, which is incident thereto at an angle of incidence. The retroreflector also includes a mirror...
US20150159187 STABLE, FUNCTIONAL CHIMERIC CELLOBIOHYDROLASE CLASS I ENZYMES  
The present disclosure relates to CBH I chimera fusion polypeptides, nucleic acids encoding the polypeptides, and host cells for producing the polypeptides.
9054871 Physical key-protected one time pad  
A device, including one or more Communication Physical Unclonable Function (CPUF) and key storage devices, the CPUF devices each including: a coherent Electromagnetic (EM) radiation source; a...
9053903 Characterization of nanoscale structures using an ultrafast electron microscope  
The present invention relates to methods and systems for 4D ultrafast electron microscopy (UEM)—in situ imaging with ultrafast time resolution in TEM. Single electron imaging is used as a...
9051345 Metalloinsertor complexes targeted to DNA mismatches  
A composition including a Rh or Ru metalloinsertor complex specifically targets mismatch repair (MMR)-deficient cells. Selective cytotoxicity is induced in MMR-deficient cells upon uptake of the...
9050444 Drug delivery and substance transfer facilitated by nano-enhanced device having aligned carbon nanotubes protruding from device surface  
The present invention relates to a nano-enhanced device for substance transfer between the device and a tissue. The device comprises a substrate with substantially aligned carbon nanotubes...
US20150155800 ACOUSTIC MECHANICAL FEED-THROUGHS FOR PRODUCING WORK ACROSS A STRUCTURE  
An apparatus that passes vibrational energy across a mechanical structure lacking a perforation. The disclosed apparatus and method provide the ability to transfer work (rotary or linear motion)...
US20150155598 Fluoride Ion Electrochemical Cell  
Electrochemical cells of the present invention are versatile and include primary and secondary cells useful for a range of important applications including use in portable electronic devices....
US20150155108 METHOD TO INCREASE THE CAPACITANCE OF ELECTROCHEMICAL CARBON NANOTUBE CAPACITORS BY CONFORMAL DEPOSITION OF NANOPARTICLES  
A method of increasing the area of carbon nanotubes used in fabricating capacitors is described. The method involves reacting carbon nanotubes with electrically conductive ions, molecules or...
US20150154347 SYSTEM AND METHOD FOR CONSTRAINED MULTISTATE REACTION PATHWAY DESIGN  
Methods and systems for designing the sequences of multiple nucleic acid strands intended to hybridize in solution via a prescribed reaction pathway are described. Sequence design is formulated as...
US20150153319 SENSING AND ACTUATION OF BIOLOGICAL FUNCTION USING ADDRESSABLE TRANSMITTERS OPERATED AS MAGNETIC SPINS  
Methods and apparatuses for sensing biological functions are disclosed. Sensors can be implanted in an organ, such as the brain, and a magnetic field gradient applied to the biological tissue. The...
US20150152435 METHOD FOR EXPRESSION OF SMALL RNA MOLECULES WITHIN A CELL  
The invention provides methods and compositions for the expression of small RNA molecules within a cell using a lentiviral vector. The methods can be used to express doubles stranded RNA...
9048431 Electronic devices employing aligned organic polymers  
The devices can be fabricated by a method that permits active polymer chains to be polymerized on the surface of an electrode such that the active polymer chains are aligned with one another. The...
9048097 Semiconductive micro- and nano-wire array manufacturing  
The disclosure provides methods of manufacturing semiconductive structures using stamping and VLS techniques.
9046680 Scanning illumination microscope  
A microscopy method and configuration provides the ability to achieve wide field view and high resolution simultaneously. A beam array generator generates an M×N light beam array that illuminates...
9046525 Method of determining the oligomeric state of a protein complex  
A method of counting protein subunits to determine the oligomeric state of an oligomeric protein complex includes tagging and expressing the protein subunits with a mass/charge tag and selectively...
9045579 Periodic nanostructures from self assembled wedge-type block-copolymers  
The invention provides a class of wedge-type block copolymers having a plurality of chemically different blocks, at least a portion of which incorporates a wedge group-containing block providing...
9045343 Carbon nanotube foams with controllable mechanical properties  
Syntheses of carbon nanotubes (CNT) are disclosed. The syntheses can take place on a thermally oxidized silicon surface placed inside a furnace prior to a reaction. The setup can have many...
9044800 High aspect ratio parts of bulk metallic glass and methods of manufacturing thereof  
Bulk metallic articles having a high-aspect ratio that are formed of bulk metallic glass, that are net-shaped and that are produced under process conditions that maximize the quality and integrity...