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Patents and Patent Applications from California Institute of Technology


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7894696 Integrated optical modulator  
Systems and methods for manipulating light with high index contrast waveguides clad with crystalline substances having that exhibit large nonlinear electro-optic constants χ2 and χ3. Waveguides f...
7894078 Single-lens 3-D imaging device using a polarization-coded aperture masks combined with a polarization-sensitive sensor  
A device and method for three-dimensional (3-D) imaging using a defocusing technique is disclosed. The device comprises a lens, at least one polarization-coded aperture obstructing the lens, a...
7894058 Single-lens computed tomography imaging spectrometer and method of capturing spatial and spectral information  
Computed tomography imaging spectrometers (“CTISs”) employing a single lens are provided. The CTISs may be either transmissive or reflective, and the single lens is either configured to tra...
7892427 Apparatus and method for magnetic-based manipulation of microscopic particles  
Apparatus and method for manipulating particles on a micro- or nano-scale. An embodiment of the present invention includes a magnetic micro-manipulation technique that utilizes micro-coils and soft...
US20110037832 Defocusing Feature Matching System to Measure Camera Pose with Interchangeable Lens Cameras  
A lens and aperture device for determining 3D information. An SLR camera has a lens and aperture that allows the SLR camera to determine defocused information.
7890842 Computer-implemented method for correcting transmission errors using linear programming  
A computer-implemented method for correcting transmission errors. According to the method, a transmitted vector corrupted by error can be recovered solving a linear program. The method has...
7889053 Remote, non-contacting personnel bio-identification using microwave radiation  
A system to remotely identify a person by utilizing a microwave cardiogram, where some embodiments segment a signal representing cardiac beats into segments, extract features from the segments, and...
7887753 Apparatus and methods for conducting assays and high throughput screening  
The present invention provides microfluidic devices and methods for using the same. In particular, microfluidic devices of the present invention are useful in conducting a variety of assays and...
7883592 Semi-solid processing of bulk metallic glass matrix composites  
A method of forming bulk metallic glass engineering materials, and more particularly a method for forming coarsening microstructures within said engineering materials is provided. Specifically, the...
US20110024617 SWITCHED FERROELECTRIC PLASMA IONIZER  
A novel ion source for ambient mass spectrometry (switched ferroelectric plasma ionizer or “SwiFerr”), which utilizes the ambient pressure plasma resulting from a sample of barium titanate [00...
7878071 Nanoindenter tip for uniaxial tension and compression testing  
The invention is an indenter tip that is modified to permit both compression testing and tensile testing on samples having dimensions smaller than approximately 1 μm. The modified indenter tip has ...
US20110020359 METHODS AND COMPOSITIONS FOR TREATING NEURONAL DAMAGE OR DEGENERATION  
This invention provides methods and compositions for reducing chondroitin-sulfate-proteoglycan-mediated inhibition of neuronal growth. The methods and compositions provided herein are particularly...
7876434 Color camera computed tomography imaging spectrometer for improved spatial-spectral image accuracy  
Computed tomography imaging spectrometers (“CTIS”s) having color focal plane array detectors are provided. The color FPA detector may comprise a digital color camera including a digital image sen...
US20110014659 ISOLATION OF UNKNOWN REARRANGED T-CELL RECEPTORS FROM SINGLE CELLS  
Disclosed herein are methods and materials for isolating and identifying T cell receptors from single cells. In some embodiments, genomic DNA from a single T cell is isolated using whole genome...
US20110008828 METHODS OF INCORPORATING AMINO ACID ANALOGS INTO PROTEINS  
The invention provides a method of incorporating nonstandard amino acids into a protein by utilizing a modified aminoacyl-tRNA synthetase to charge the nonstandard amino acid to a modified tRNA,...
7868783 Cellular-based preemption system  
A cellular-based preemption system that uses existing cellular infrastructure to transmit preemption related data to allow safe passage of emergency vehicles through one or more intersections. A...
7867724 Compositions and method of treating hypoxia-associated diseases  
Hypoxia, a state of lower than normal tissue oxygen tension, has recently been implicated in a host of human diseases, including cancer, heart disease, and neurological disorders. Novel...
US20110004096 ELECTROMAGNETIC CELLULAR TOMOGRAPHY  
The invention provides an electromagnetic cellular tomograph and methods of operating such a device. An array of structures is configured to apply probe signals to cells or tissues of interest that...
US20110003683 NANOSTRUCTURED PLATINUM ALLOYS FOR USE AS CATALYST MATERIALS  
A series of binary and ternary Pt-alloys, that promote the important reactions for catalysis at an alloy surface; oxygen reduction, hydrogen oxidation, and hydrogen and oxygen evolution. The first...
US20110001980 OPTICAL PHASE PROCESSING IN A SCATTERING MEDIUM  
An optical phase processing system for a scattering medium. A first beam has a direction and a wavefront and the first beam is configured to enter a holographic recording medium. A scattering...
US20110001392 HIGHLY EFFICIENT, CHARGE DEPLETION-MEDIATED, VOLTAGE-TUNABLE ACTUATION EFFICIENCY AND RESONANCE FREQUENCY OF PIEZOELECTRIC SEMICONDUCTOR NANOELECTROMECHANICAL SYSTEMS RESONATORS  
A nanoelectromechanical systems (NEMS) device and method for using the device provide for a movable member that includes a region of low conductivity over which an electric field is developed. A...
7864305 Self-contained underwater velocimetry apparatus  
A velocimetry apparatus and method for the collection of target-specific images of fluid motions are disclosed. The apparatus includes a camera and a light source. The camera collects and provides...
7864071 Emergency vehicle traffic signal preemption system  
An emergency vehicle traffic light preemption system for preemption of traffic lights at an intersection to allow safe passage of emergency vehicles. The system includes a real-time status monitor...
7863030 Regio- and enantioselective alkane hydroxylation with modified cytochrome P450  
Cytochrome P450 BM-3 from Bacillus megaterium was engineered using a combination of directed evolution and site-directed mutagenesis to hydroxylate linear alkanes regio- and enantioselectively...
7862000 Microfluidic method and structure with an elastomeric gas-permeable gasket  
A microfluidic structure and method, where the structure comprises a featureless gasket layer allowing for efficient and reproducible structure production and assembly. Layering methods allow for...
US20100331976 PROSTHETIC DEVICES AND METHODS AND SYSTEMS RELATED THERETO  
Prosthetic devices, methods and systems are disclosed. Eye position and/or neural activity of a primate are recorded and combined. The combination signal is compared with a predetermined signal....
US20100330455 ADVANCED SOLID ACID ELECTROLYTE COMPOSITES  
Solid acid/surface-hydrogen-containing secondary component electrolyte composites, methods of synthesizing such materials, electrochemical device incorporating such materials, and uses of such...
7858720 Co-polymer films for sensors  
Embodiments include a sensor comprising a co-polymer, the co-polymer comprising a first monomer and a second monomer. For some embodiments, the first monomer is poly-4-vinyl pyridine, and the...
7858578 Methods of inducing neuronal growth by a Fucose-α(1-2) galactose (fuc-α(1-2) gal) moiety and a lectin  
Fucose galactose carbohydrates have been shown to induce neuronal outgrowth. The invention includes methods of inducing neuronal outgrowth using carbohydrates, assemblies, and polymers bearing...
7858059 Molecular sieves for improved hydrocarbon traps  
Molecular sieves and the use of such materials as hydrocarbon traps, particularly for reducing the emissions associated with the combustion of hydrocarbon fuels are described. Specifically, the use...
US20100319746 HIGH EFFICIENCY THERMOELECTRIC POWER GENERATION USING ZINTL-TYPE MATERIALS  
The invention disclosed herein relates to thermoelectrically-active p-type Zintl phase materials as well as devices utilizing such compounds. Such thermoelectric materials and devices may be used...
US20100316172 INCOMPRESSIBLE RF RECEIVER  
An incompressible receiver for minimizing undesired higher-order nonlinear distortion products includes a first receiver path configured to receive an input signal having at least one non-baseband...
7853637 Method and system for pipelining saturated accumulation and other loops with loop-carried dependencies  
Aggressive pipelining allows Field Programmable Gate Arrays (FPGAs) to achieve high throughput on many Digital Signal Processing applications. However, cyclic data dependencies in the computation...
7853514 Method and apparatus for providing a market environment  
The system provides two-sided local markets that enable local and/or intermittent resource allocation through a market model. The system provides a method for defining goods, services or assets are...
7851146 Nucleic acid mediated electron transfer  
The present invention provides for the selective covalent modification of nucleic acids with redox active moieties such as transition metal complexes. Electron donor and electron acceptor moieties...
US20100307551 FABRICATION OF HIGH-TEMPERATURE THERMOELECTRIC COUPLE  
The present invention relates to a high-temperature thermoelectric couple and the method for making the same. The method requires a very small number of fabrication steps. It includes an act of...
7847099 Non-metallocene organometallic complexes and related methods and systems  
A non-metallocene organometallic complex comprising a tridentate ligand and a metal bonded to a tridentate ligand, wherein two substituted aryl groups in the tridentate ligand are connected to a...
7847019 Functionalized polymers using protected thiols  
A process for the preparation of functional molecules using the thiol-ene coupling reaction and a process for the preparation of protected functional thiols, specifically thioesters is provided....
7846743 Uses of parylene membrane filters  
The invention provides parylene membrane filters, filter devices and methods of making them and using them in the mechanical separation of cells and particles by size. The provision of parylene...
7846393 Membrane filter for capturing circulating tumor cells  
The present invention provides a parylene-based membrane filter device for capturing of circulating tumor cells (CTC). The membrane filter has an array of holes having a predetermined geometric...
US20100304464 STABLE, FUNCTIONAL CHIMERIC CELLOBIOHYDROLASES  
The present disclosure relates to CBH II chimera fusion polypeptides, nucleic acids encoding the polypeptides, and host cells for producing the polypeptides.
US20100300148 TOUGH IRON-BASED BULK METALLIC GLASS ALLOYS  
A family of iron-based, phosphor-containing bulk metallic glasses having excellent processibility and toughness, methods for forming such alloys, and processes for manufacturing articles therefrom...
7843565 Optical gas monitor  
A frequency modulated spectroscopy system, including a photo-detector, a band-pass filter to filter the output of the photo-detector, and a rectifier to demodulate. The band-pass filter has a...
7842793 Methods of making nucleic acid nanostructures  
The disclosure relates to methods and composition for generating nanoscale devices, systems, and enzyme factories based upon a nucleic acid nanostructure the can be designed to have a predetermined...
7842517 Method and compositions for the detection of protein glycosylation  
The invention provides methods and compositions for the rapid and sensitive detection of post-translationally modified proteins, and particularly of those with post-translational glycosylations....
US20100294041 MICROFABRICATED IMPLANTABLE WIRELESS PRESSURE SENSOR FOR USE IN BIOMEDICAL APPLICATIONS AND PRESSURE MEASUREMENT AND SENSOR IMPLANTATION METHODS  
A variable capacitor, a microfabricated implantable pressure sensor including a variable capacitor and an inductor, and related pressure measurement and implantation methods. The inductor may have...
7840625 Methods for performing fast discrete curvelet transforms of data  
Fast digital implementations of the second generation curvelet transform for use in data processing are disclosed. One such digital transformation is based on unequally-spaced fast Fourier...
7837913 High aspect ratio template and method for producing same  
Millimeter to nano-scale structures manufactured using a multi-component polymer fiber matrix are disclosed. The use of dissimilar polymers allows the selective dissolution of the polymers at...
US20100291385 FABRICATION OF VERTICALLY ALIGNED METALLIC NANOPILLARS  
Solid and hollow cylindrical nanopillars with nanoscale diameters are provided. Also provides is a method of making such nanopillars using electron beam lithography followed by the electroplating.
US20100290049 OPTOFLUIDIC MICROSCOPE DEVICE  
An optofluidic microscope device is disclosed. The device includes a fluid channel having a surface and an object such as a bacterium or virus may flow through the fluid channel. Light imaging...