Patents and Patent Applications from California Institute of Technology


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9217151 Versatile nucleic acid hairpin motif for programming biomolecular self-assembly pathways  
The present invention relates generally to programming of biomolecular self-assembly pathways and related methods and constructs. A versatile nucleic acid hairpin motif for programming...
US20150359668 LIGHT DELIVERY DEVICE AND RELATED COMPOSITIONS, METHODS AND SYSTEMS  
Devices and systems for delivering light to a target are described. Methods of using such light delivery device and system are also described. A method of using a photosensitizing compound with...
9215114 Double-sampling receiver with dynamic offset modulation for optical and electrical signaling  
A receiver architecture is disclosed which employs an RC double-sampling front-end and dynamic offset modulation technique. A low-voltage double-sampling technique provides high power efficiency...
9214811 Devices and methods for harvesting power from arrays of wind turbines  
Variable frequency alternate current (VFAC) bus arrangements and systems using such VFAC bus arrangements are described, such as arrays of turbines. Such systems have a centrally located power...
9214787 III-V photonic crystal microlaser bonded on silicon-on-insulator  
Novel methods and systems for miniaturized lasers are described. A photonic crystal is bonded to a silicon-on-insulator wafer. The photonic crystal includes air-holes and can include a waveguide...
9214581 Barrier infrared detectors on lattice mismatch substrates  
Systems and methods of implementing barrier infrared detectors on lattice mismatched substrates are provided. The barrier infrared detector systems combine an active detector structure (e.g.,...
9212994 Fluorescence detector, filter device and related methods  
A microfluidic filter is disclosed. The filter can be used with onchip fluid filtration such as whole blood filtration for microfluidic blood analysis. The filter is able to filter the necessary...
9211564 Methods of fabricating a layer of metallic glass-based material using immersion and pouring techniques  
Systems and methods in accordance with embodiments of the invention implement layers of metallic glass-based materials. In one embodiment, a method of fabricating a layer of metallic glass...
US20150357541 COMPLIANT INTERFACIAL LAYERS IN THERMOELECTRIC DEVICES  
A thermoelectric power generation device is disclosed using one or more mechanically compliant and thermally and electrically conductive layers at the thermoelectric material interfaces to...
US20150357075 METHODS AND DEVICES FOR IN SITU SYNTHESIS OF METAL OXIDES IN CARBON NANOTUBE ARRAYS  
A method for controlling microstructural and nanostructural arrangement of nominally-aligned arrays of carbon nanotubes (CNTs) is disclosed. The method comprises synthesizing metal oxide particles...
US20150355098 ROTATING SCATTERING PLANE BASED NONLINEAR OPTICAL SPECTROMETER TO STUDY THE CRYSTALLOGRAPHIC AND ELECTRONIC SYMMETRIES OF CRYSTALS  
A method for measuring nonlinear Electromagnetic (EM) radiation emitted by a material, comprising rotating a beam of EM radiation to form a rotating beam; irradiating a surface of a material with...
US20150353619 Non-Canonical Insulins and Their Uses  
In some aspects, the invention relates to an insulin derivative, comprising a cyclic amino acid at position B28 or B29, wherein the cyclic amino acid is not L-proline. In some aspects, the...
9209375 Methods and devices for controlling thermal conductivity and thermoelectric power of semiconductor nanowires  
Methods and devices for controlling thermal conductivity and thermoelectric power of semiconductor nanowires are described. The thermal conductivity and the thermoelectric power are controlled...
9207532 Photoinitiated olefin methathesis polymerization  
The present invention provides photosensitive compositions and methods of patterning a polymeric image on a substrate, said methods comprising; (a) depositing a layer of photosensitive composition...
9207318 Damage proxy map from interferometric synthetic aperture radar coherence  
A method, apparatus, and article of manufacture provide the ability to generate a damage proxy map. A master coherence map and a slave coherence map, for an area prior and subsequent to...
9206419 Targeting domain and related signal activated molecular delivery  
Provided herein are signal activatable molecular constructs for enzyme-assisted delivery of molecules and related components, such as a sensor domain, compositions, methods and systems.
9206042 Methods and materials for the catayltic reduction of carbon dioxide  
The present disclosure is directed to methods of catalytically reducing carbon dioxide, each method comprising: contacting a composition comprising a spinel-type transition iron oxide with an...
9205423 High throughput screening of crystallization of materials  
High throughput screening of crystallization of a target material is accomplished by simultaneously introducing a solution of the target material into a plurality of chambers of a microfabricated...
US20150346753 Systems and Methods for Convex Relaxations and Linear Approximations for Optimal Power Flow in Multiphase Radial Networks  
Centralized node controllers in accordance with embodiments of the invention enable linear approximation of optimal power flow. One embodiment includes a centralized node controller including: a...
US20150346726 CONTROLLABLE BUOYS AND NETWORKED BUOY SYSTEMS  
Buoyant sensor networks are described, comprising floating buoys with sensors and energy harvesting capabilities. The buoys can control their buoyancy and motion, and can organize communication in...
US20150344932 METHOD AND COMPOSITIONS FOR THE DETECTION OF PROTEIN GLYCOSYLATION  
The invention provides methods and compositions for the rapid and sensitive detection of post-translationally modified proteins, and particularly of those with posttranslational glycosylations....
US20150344523 MUTANT AKT-SPECIFIC CAPTURE AGENTS, COMPOSITIONS, AND METHODS OF USING AND MAKING  
The present application provides stable peptide-based Akt capture agents and methods of use as detection and diagnosis agents and in the treatment of diseases and disorders. The application...
US20150344109 CONTROLLABLE BUOYS AND NETWORKED BUOY SYSTEMS  
Buoyant sensor networks are described, comprising floating buoys with sensors and energy harvesting capabilities. The buoys can control their buoyancy and motion, and can organize communication in...
US20150340863 Systems and Methods for Optimal Power Flow on a Radial Network  
Node controllers and power distribution networks in accordance with embodiments of the invention enable distributed power control. One embodiment includes a node controller including a distributed...
9196426 Electrodes incorporating nanostructured polymer films for electrochemical ion storage  
Ion storage electrodes formed by coating an underlying substrate with a nanofibrillar film of structured conjugate polymer nanofibers and methods of forming such electrodes are described herein....
US20150333482 INDEX-COUPLED DISTRIBUTED-FEEDBACK SEMICONDUCTOR QUANTUM CASCADE LASERS FABRICATED WITHOUT EPITAXIAL REGROWTH  
Quantum cascade (QC) lasers and methods of fabricating such QC lasers are provided. The QC lasers incorporate a DFB grating without requiring the use of relying on epitaxial regrowth processes....
US20150333480 HIGH-COHERENCE SEMICONDUCTOR LIGHT SOURCES  
A laser resonator includes an active material, which amplifies light associated with an optical gain of the resonator, and passive materials disposed in proximity with the active material. The...
US20150332125 AUTOMATED FEATURE ANALYSIS, COMPARISON, AND ANOMALY DETECTION  
Novel methods and systems for automated data analysis are disclosed. Data can be automatically analyzed to determine features in different applications, such as visual field analysis and...
US20150331232 ULTRA-FAST MECHANICAL SHUTTER  
An electro-mechanical shutter is described. The fast operation is based on a coil operated via a current, where the coil can move within a set of magnets to provide opening and closing of a...
US20150331228 PTYCHOGRAPHY IMAGING SYSTEMS AND METHODS WITH CONVEX RELAXATION  
Certain aspects pertain to ptychographic imaging systems and methods with convex relaxation. In some aspects, a ptychographic imaging system with convex relaxation comprises one or more...
US20150331193 SELF-EQUALIZING PHOTO DETECTOR  
A self-equalizing photo-detector (SEPD) includes, in part, a multitude of optical splitters and photo detectors, and at least one optical delay element. The first optical splitter splits an...
US20150329961 CARBON NANOTUBE FOAMS WITH CONTROLLABLE MECHANICAL PROPERTIES  
Syntheses of carbon nanotubes (CNT) are disclosed. The syntheses can take place on a thermally oxidized silicon surface placed inside a furnace prior to a reaction. The setup can have many...
US20150329769 ULTRA-LIGHT ULTRA-STRONG PROPPANTS  
The present invention provides a method of preparing a proppant material by heating a reaction mixture comprising a plurality of oxides in a reactive atmosphere to a temperature above the melting...
US20150329603 Compositions and Methods Related to Parasites  
In some aspects, the invention relates to compositions and methods for preventing or treating a hookworm infection. In some aspects, the invention relates to nucleic acids, peptides, proteins,...
US20150329362 SIMPLE METHOD FOR PRODUCING SUPERHYDROPHOBIC CARBON NANOTUBE ARRAY  
Efficient methods for producing a superhydrophobic carbon nanotube (CNT) array are set forth. The methods comprise providing a vertically aligned CNT array and performing vacuum pyrolysis on the...
US20150328616 SURFACE MEDIATED SYNTHESIS OF POLYNUCLEOTIDES, POLYPEPTIDES AND POLYSACCHARIDES AND RELATED MATERIALS, METHODS AND SYSTEMS  
Surface mediated polymer synthesizing methods and related systems and materials are described where monomers are attached to monomer binding regions on a surface and subsequently form chemical...
US20150328313 PHOTOACTIVATED MOLECULES FOR LIGHT-INDUCED MODULATION OF THE ACTIVITY OF ELECTRICALLY EXCITABLE CELLS AND METHODS OF USING SAME  
Methods and compositions modulate the activity of electrically excitable cells. Photovoltaic compounds which, upon exposure to light energy, increase or decrease the electrical activity of cells....
9191371 Network coding-based anonymous communication  
A computer-based peer-to-peer anonymous networking using a coding scheme with a formal information theoretic security characterization to construct a corresponding overlay subgraph is presented. A...
9190724 Phased antenna array for global navigation satellite system signals  
Systems and methods for phased array antennas are described. Supports for phased array antennas can be constructed by 3D printing. The array elements and combiner network can be constructed by...
9190698 Lithium-ion electrolytes with improved safety tolerance to high voltage systems  
The invention discloses various embodiments of electrolytes for use in lithium-ion batteries, the electrolytes having improved safety and the ability to operate with high capacity anodes and high...
9190042 Systems and methods for musical sonification and visualization of data  
The current disclosure is directed to systems and methods for automatically converting multi-dimensional, complex data sets to musical symbols while representing the converted data in an animated...
9188584 Capture agents and related compositions, methods and systems  
Multi-ligand capture agents comprising two or more ligands are described, and related compositions, methods and systems.
9187812 Thermoplastic joining and assembly of bulk metallic glass composites through capacitive discharge  
Systems and methods for joining BMG Composites are disclosed. Specifically, the joining of BMG Composites is implemented so as to preserve the amorphicity of their matrix phase and the...
9186327 Carrier nanoparticles and related compositions, methods and systems  
Carrier nanoparticles comprising a polymer containing a polyol coupled to a polymer containing a boronic acid, configured to present the polymer containing a boronic acid to an environment...
US20150324253 RANK-MODULATION REWRITING CODES FOR FLASH MEMORIES  
Rank modulation has been recently proposed as a scheme for storing information in flash memories. Three improved aspects are disclosed. In one aspect the minimum push-up scheme, for storing data...
US20150323322 Automated Vessel Navigation Using Sea State Prediction  
Systems and methods for sea state prediction and autonomous navigation in accordance with embodiments of the invention are disclosed. One embodiment of the invention includes a method of...
US20150322395 METHODS AND DEVICES FOR MICRO-ISOLATION, EXTRACTION, AND/OR ANALYSIS OF MICROSCALE COMPONENTS  
Provided herein are devices and methods for the micro-isolation of biological cellular material. A micro-isolation apparatus described can comprise a photomask that protects regions of interest...
US20150322207 CARRIER NANOPARTICLES AND RELATED COMPOSITIONS, METHODS AND SYSTEMS  
Carrier nanoparticles comprising a polymer containing a polyol coupled to a polymer containing a boronic acid, configured to present the polymer containing a boronic acid to an environment...
US20150321195 TEMPERATURE CONTROL DEVICES AND METHODS  
Temperature control devices and methods are described. The described temperature control devices and methods comprise optical emission and detection assemblies and can be used in PCR and qPCR...
9182387 Methods for cancer detection, diagnosis and prognosis  
The present invention provides a method for diagnosing cancer, predicting a disease outcome or response to therapy in a patient sample. The method involves isolating a circulating tumor cell...