Patents and Patent Applications from Brown University


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US20120033217 METHOD AND APPARATUS FOR DETECTING MULTIPLE OPTICAL WAVE LENGTHS  
Optical gratings that perform a number of functions at various wavelengths are formed by various methods that preserve spectral information within a wavelength band, the functions including:...
US20120009267 NANOPARTICLE COMPOSITIONS AND METHODS FOR IMPROVED ORAL DELIVERY OF ACTIVE AGENTS  
Nanoparticles, compositions, and methods for the improved uptake of active agents are disclosed herein. The compositions contain a monodisperse population of nanoparticles, preferably including an...
8072005 Apparatus, method and computer program product providing radial addressing of nanowires  
Disclosed is a method to construct a device that includes a plurality of nanowires (NWs) each having a core and at least one shell. The method includes providing a plurality of radially encoded NWs...
US20110289043 COMPUTATIONAL METHODS AND COMPOSITIONS  
The invention in some aspects relates to methods, devices and compositions for evaluating material properties, such as mechanical and rheological properties of substances, particularly biological...
US20110288080 Nitrofuran Compounds for the Treatment of Cancer and Angiogenesis  
The invention is directed to the synthesis and use of nitrofuran compounds, especially Nifurtimox, as medicaments to treat cancer, especially neuroblastoma, and to inhibit angiogenesis. The...
8041163 Method and apparatus for detecting multiple optical wavelengths  
Optical gratings that perform a number of functions at various wavelengths are formed by various methods that preserve spectral information within a wavelength band, the functions including:...
US20110204219 SYSTEM AND METHODS FOR DETERMINING MOLECULES USING MASS SPECTROMETRY AND RELATED TECHNIQUES  
The present invention generally relates to mass spectrometry and related techniques, and in some cases, to determining single species using mass spectrometry. In certain instances, polymers such as...
US20110183910 BIGLYCAN AND RELATED THERAPEUTICS AND METHODS OF USE  
The invention provides compositions and methods for treating, preventing, and diagnosing diseases or conditions associated with an abnormal level or activity of biglycan; disorders associated with...
7978887 Methods and apparatus for identifying subject matter in view data  
In one aspect, a method and apparatus for detecting subject matter of interest in view data obtained by scanning an object including generating a filter adapted to respond to the subject matter of...
7974221 Efficient content authentication in peer-to-peer networks  
In one exemplary embodiment, a method includes: providing an abstract tree structure having a root node, tree nodes, and leaf nodes, each leaf node corresponds to a portion of data; mapping first...
US20110125263 METHOD FOR PRODUCING NANOSTRUCTURES ON A SURFACE OF A MEDICAL IMPLANT  
A method for treating a surface of a medical implant to create nanostructures on the surface that results in increased in-vivo chondrocyte adhesion to the surface. Further, disclosed is a method to...
US20110094453 IMPROVED APPARATUS AND METHOD FOR ASSESSING VISUAL LEARNING  
An improved test apparatus and method for assessing visual learning in mammals is provided. The stimuli presented to the mammal are disposed and arranged on the floor of the test apparatus instead...
7913155 Synchronizing method and system  
A synchronization system and method. Text data is received by a computing device. The text data is associated with audio/video data. The audio/video data is generated during a related performance....
US20110059904 SERUM-BASED, DIAGNOSTIC, BIOLOGICAL ASSAY TO PREDICT PREGNANCY DISORDERS  
The invention provides serum-based, diagnostic, biological assays for predicting disorders of pregnancy resulting from poor trophoblast and/or placental ischemia, including preeclampsia. Serum...
US20110053854 TREATMENT OF MUSCULAR DYSTROPHIES AND RELATED DISORDERS  
The invention provides, among other aspects, compositions and methods for treating, preventing, and diagnosing diseases or conditions associated with an abnormal level or activity of biglycan;...
US20110053766 NANOSTRUCTURED SORBENT MATERIALS FOR CAPTURING ENVIRONMENTAL MERCURY VAPOR  
The present invention is a method and material for using a sorbent material to capture and stabilize mercury. The method for using sorbent material to capture and stabilize mercury contains the...
US20110052463 NANOSTRUCTURED SORBENT MATERIALS FOR CAPTURING ENVIRONMENTAL MERCURY VAPOR  
The present invention is a method and material for using a sorbent material to capture and stabilize mercury. The method for using sorbent material to capture and stabilize mercury contains the...
US20110049045 NANOSTRUCTURED SORBENT MATERIALS FOR CAPTURING ENVIRONMENTAL MERCURY VAPOR  
The present invention is a method and material for using a sorbent material to capture and stabilize mercury. The method for using sorbent material to capture and stabilize mercury contains the...
US20110048982 NANOSTRUCTURED SORBENT MATERIALS FOR CAPTURING ENVIRONMENTAL MERCURY VAPOR  
The present invention is a method and material for using a sorbent material to capture and stabilize mercury. The method for using sorbent material to capture and stabilize mercury contains the...
7894070 Optical method and system for the characterization of laterally-patterned samples in integrated circuits  
Disclosed is a method for characterizing a sample having a structure disposed on or within the sample, comprising the steps of applying a first pulse of light to a surface of the sample for...
US20110036171 ENHANCED ULTRA-HIGH RESOLUTION ACOUSTIC MICROSCOPE  
An optical-acoustic transducer structure includes at least one metal or semiconducting film in which a part of a pump light pulse is absorbed to generate a sound pulse; and at least one dielectric...
US20110028333 DIAGNOSING, PROGNOSING, AND EARLY DETECTION OF CANCERS BY DNA METHYLATION PROFILING  
A method of employing DNA methylation analysis for the diagnosis, prognosis, and prediction of cancer.
US20100332203 Optical Method For the Characterization of Laterally-Patterned Samples in Integrated Circuits  
Disclosed is a method for characterizing a sample having a structure disposed on or within the sample, comprising the steps of applying a first pulse of light to a surface of the sample for...
US20100323262 REACTANT DELIVERY TO A REACTIVE SURFACE IN A CHANNEL  
The present invention provides geometric arrangements for channels through which liquids or other fluids can be made to flow, for enhanced performance of fuel cells or other chemical or biochemical...
7838687 Redox-active polymers and their applications  
The present invention provides a monomer comprising the structure: wherein R1 and/or R1′ are selected from the group consisting of MeO, EtO, COF3, SO4H, SO3−, SO3H, H, CHNO4S2F3, C5H4N2O6S2F6, C10...
7816322 Biglycan and related therapeutics and methods of use  
The invention provides compositions and methods for treating, preventing, and diagnosing diseases or conditions associated with an abnormal level or activity of biglycan; disorders associated with...
7809736 Importance ranking for a hierarchical collection of objects  
A system and method of obtaining an importance ranking for a hierarchical collection of objects. The hierarchical collection of objects is represented as a tree containing a plurality of nodes, and...
US20100228745 SYSTEM, METHOD, AND APPARATUS FOR SORTING AT LEAST PARTIALLY DYNAMIC DATA  
Embodiments of methods, apparatuses, devices and systems associated with sorting candidate values are disclosed.
7782471 Optical method for the characterization of laterally-patterned samples in integrated circuits  
Disclosed is a method for characterizing a sample having a structure disposed on or within the sample, comprising the steps of applying a first pulse of light to a surface of the sample for...
7767063 Photo-formed metal nanoparticles and aerogel materials comprising the same  
Transparent monolithic aerogels based on silica, the bioderived polymer chitosan, and coordinated ions are employed to serve as a three-dimensional scaffold decorated with metal ions such as Au, Pt...
7759314 Treatment of muscular dystrophies and related disorders  
The invention provides, among other aspects, compositions and methods for treating, preventing, and diagnosing diseases or conditions associated with an abnormal level or activity of biglycan;...
US20100110935 Efficient Content Authentication In Peer-To-Peer Networks  
A method and distributed network are provided. The method includes: providing an abstract tree structure having a root node, a plurality of tree nodes, and a plurality of leaf nodes, wherein each...
7693370 Method and apparatus for processing optical signals with supergratings  
An optical component including at least one optical supergrating is provided. The optical supergrating includes a quantized refractive index profile adapted to exhibit a finite plurality of...
7678562 Addressable nanopores and micropores including methods for making and using same  
Featured are devices and systems embodying one or more electrically-addressable-solid-state nanopores useful for sensing and/or characterizing single macromolecules as well as sequencing DNA or...
US20100050276 Transgenic non-human animal models of apoptosis-mediated conditions  
A transgenic non-human animal whose genome comprises a stable integration of a transgene that encodes at least one Fas-ligand protein operably-linked to a tetracycline-inducible promoter includes...
7648993 Methods of treating disorders with Group I mGluR antagonists  
mGluR5 antagonists are used for the treatment and prevention of disorders, including Fragile X, autism, mental retardation, schizophrenia and Down's Syndrome. The methods of the invention can be...
US20100010235 Method of using rhodium quinonoid catalysts  
In accordance with aspects of the invention methods of using rhodium hydroquinone catalysts for the conjugate addition of boronic acids are disclosed.
7624640 Opto-acoustic methods and apparatus for performing high resolution acoustic imaging and other sample probing and modification operations  
An opto-acoustic transducer assembly includes a substrate; at least one layer of opto-acoustic material coupled to a surface of the substrate, where the at least one layer of opto-acoustic material...
7612038 Biglycan and related therapeutics and methods of use  
The invention provides compositions and methods for treating, preventing, and diagnosing diseases or conditions associated with an abnormal level or activity of biglycan; disorders associated with...
US20090213375 Optical method for the characterization of laterally-patterned samples in integrated circuits  
Disclosed is a method for characterizing a sample having a structure disposed on or within the sample, comprising the steps of applying a first pulse of light to a surface of the sample for...
7569734 Method of using rhodium quinonoid catalysts  
In accordance with aspects of the invention methods of using rhodium hydroquinone catalysts for the conjugate addition of boronic acids are disclosed.
US20090191099 HIGH-THROUGPUT SOLVENT EVAPORATOR AND GAS MANIFOLD WITH UNIFORM FLOW RATES AND INDEPENDENT FLOW CONTROLS  
The evaporator (10) efficiently evaporates solvent and/or introduces gases to multiple samples. The evaporator (10) contains a top plate (20) and a bottom plate (30). The top plate (20) is mated to...
US20090180736 METHOD AND APPARATUS FOR DETECTING MULTIPLE OPTICAL WAVELENGTHS  
Optical gratings that perform a number of functions at various wavelengths are formed by various methods that preserve spectral information within a wavelength band, the functions including:...
7551657 Magneto-optoelectronic switch and sensor  
A Magneto-Optoelectronic Device MOD (10) includes a magnetic sensing device (12), such as a magnetoresistive device or a magnetic tunnel junction device, that is combined with a semiconductor light...
7543791 Tunable inverse pendulum vibration isolation system  
A vibration isolation system couples two resonant systems to provide isolation of transverse vibrational motions. The first system incorporates a plurality of tunable inverse pendulum assemblies....
US20090123053 METHODS AND APPARATUS FOR MODEL-BASED DETECTION OF STRUCTURE IN VIEW DATA  
In one aspect, a method and apparatus for determining a value for at least one parameter of a configuration of a model associated with structure of which view data has been obtained including...
US20090092875 FUEL CELL, MEMBRANE ELECTRODE ASSEMBLY  
An acid resistant composite catalyst comprising dumbbell-shaped composite nanoparticles each comprising a noble metal nanoparticle epitaxially conjugated to a ferrite particle, and/or flower-shaped...
7505154 Optical method for the characterization of laterally patterned samples in integrated circuits  
Disclosed is a method for characterizing a sample having a structure disposed on or within the sample, comprising the steps of applying a first pulse of light to a surface of the sample for...
US20090052484 Magneto-optoelectronic switch and sensor  
A Magneto-Optoelectronic Device MOD (10) includes a magnetic sensing device (12), such as a magnetoresistive device or a magnetic tunnel junction device, that is combined with a semiconductor light...
7496257 Method and apparatus for detecting multiple optical wavelengths  
Optical gratings that perform a number of functions at various wavelengths are formed by various methods that preserve spectral information within a wavelength band, the functions including:...
Matches 1 - 50 out of 315 1 2 3 4 5 6 7 >