Sign up

Patents and Patent Applications from Brown University


Match Document Document Title
US20150166517 COMPOUNDS FOR THE TREATMENT AND PREVENTION OF INFECTIONS  
Provided herein are compounds of Formula (I) or (II): (I) (II) pharmaceutically acceptable salts, tautomers, prodrugs, and stereoisomers thereof, and pharmaceutical compositions thereof, wherein...
9057698 Methods of chemoselective derivation of multiple classes of metabolites  
Chemoselective derivatization of biological amines, carboxylic acids, aldehydes or ketones are employed in methods to detect a plurality of components, or members of a component, such as...
9041931 Substrate analysis using surface acoustic wave metrology  
A system for imposing and analyzing surface acoustic waves in a substrate to determine characteristics of the substrate is disclosed. Optical elements and arrangements for imposing and analyzing...
9038829 Nanostructured sorbent materials for capturing environmental mercury vapor  
The present invention is a method and material for using a sorbent material to capture and stabilize mercury. The method for using sorbent material to capture and stabilize mercury contains the...
US20150141926 Intracranial Fixation Device  
A fixation device including a base structure such as a faceplate having an inferior surface capable of contacting a surface of a skull of a patient, having a superior surface, and defining at...
US20150140558 Methods of Identifying and Isolating Cells Using Molecular Beacons  
Methods are provided for isolating lineage-specific cells from a population of cells using molecular beacons which bind to mRNA markers and then isolating the lineage specific cells from the...
US20150139525 METHODS AND APPARATUS FOR MODEL-BASED DETECTION OF STRUCTURE IN VIEW DATA  
In one aspect, a method for determining a value for at least one parameter of a configuration of a model, the model associated with structure of which view data has been obtained from at least one...
US20150126457 NEUROPROTECTIVE COMPOSITION AND METHOD OF USE  
A therapeutic composition for treating brain injury comprising a polyarginine peptide of from 5 to 9 arginines, and further comprising 1 or more terminal cysteines. The composition is administered...
US20150121575 DEVICE AND METHOD FOR MEASURING DISTRIBUTION OF ATOMIC RESOLUTION DEFORMATION  
The present invention relates to an atomic resolution deformation distribution measurement device that can measure a deformation rate of an atomic scale with low expense by improving resolution...
US20150120260 NON-CONVEX HULL SURFACES  
The invention is a computer implemented method, device, system, or article for reconstructing a surface of an object. In particular, the invention comprises estimating a non-convex hull signed...
US20150119753 BURR HOLE MOUNTED STEREOTACTIC BIOPSY DEVICE  
A device for performing a biopsy on a brain is disclosed. The device includes a mount adapted for attachment to a burr hole on the skull of a patient. The mount has a body with a threaded surface...
US20150116316 VIRTUAL REALITY METHODS AND SYSTEMS  
Some aspects include a virtual reality device configured to present to a user a virtual environment. The virtual reality device comprises a tracking device including at least one camera to acquire...
US20150108423 APPARATUS, METHOD AND COMPUTER PROGRAM PRODUCT PROVIDING RADIAL ADDRESSING OF NANOWIRES  
Disclosed is a method to construct a device that includes a plurality of nanowires (NWs) each having a core and at least one shell. The method includes providing a plurality of radially encoded...
US20150100376 METHOD AND SYSTEM FOR USING NEUROSCIENCE TO PREDICT CONSUMER PREFERENCE  
A system and method provides techniques and analysis tools for measuring how individuals perceive and respond to valences and more subtle “micro-valences” present in stimuli. The invention...
9003561 Device and method for measuring distribution of atomic resolution deformation  
The present invention relates to an atomic resolution deformation distribution measurement device that can measure a deformation rate of an atomic scale with low expense by improving resolution...
US20150076408 RED, GREEN, AND BLUE LASING ENABLED BY SINGLE-EXCITON GAIN IN COLLOIDAL QUANTUM DOT FILMS  
The methods and materials described herein contemplate the use films of colloidal quantum dots as a gain medium in a vertical-cavity surface-emitting laser. The present disclosure demonstrates a...
8978155 Apparatus, methods, and computer program products providing dynamic provable data possession  
In one exemplary embodiment, a method includes: storing data for a file, organized as blocks, each having a portion of the file; and maintaining a skip list for the data. The skip list is an...
8942456 Image reconstruction from incomplete fourier measurements and prior edge information  
Systems and methods of image reconstruction that can reduce the number of Fourier transform measurements required to obtain an exact or stable reconstruction of target images, using prior edge...
US20150024495 DEVICE AND METHOD FOR ENGINEERING LIVING TISSUES  
A device for assembling aggregations of adherent cells includes a gripper moveable within an assembly vessel that fixes aggregations of adherent cells at a membrane of the gripper and, by movement...
US20150003737 METHODS AND APPARATUS FOR IDENTIFYING SUBJECT MATTER IN VIEW DATA  
In one aspect, a method and apparatus for detecting subject matter of interest in view data obtained by scanning an object including generating a filter adapted to respond to the subject matter of...
US20140370246 Substrate with Graphene-based Layer  
The present invention is directed to a barrier layer including graphene-based planar sheets disposed on a substrate. Exemplary uses include environmental barriers.
US20140333614 SYSTEM AND METHOD FOR SIMULATING REALISTIC CLOTHING  
Systems, methods, and computer-readable storage media for simulating realistic clothing. The system generates a clothing deformation model for a clothing type, wherein the clothing deformation...
8883568 Method providing radial addressing of nanowires  
Disclosed is a method to construct a device that includes a plurality of nanowires (NWs) each having a core and at least one shell. The method includes providing a plurality of radially encoded...
US20140327913 SYSTEMS AND METHODS ENABLING HIGH-THROUGHPUT, REAL TIME DETECTION OF ANALYTES  
System and methods for detecting analytes are provided. The system includes a plasmonic interferometer with a first surface having a first and second scattering element and an aperture disposed...
8869992 Lighting apparatus for capturing and stabilizing mercury  
The present invention is a method and material for using a sorbent material to capture and stabilize mercury. The method for using sorbent material to capture and stabilize mercury contains the...
US20140302109 Nanotubes and Compositions Thereof  
The present invention is directed to implants and the modification of the surface of implants using amino acid or polypeptide functionalized rosette nanotubes.
US20140295538 DEVICE AND SYSTEM FOR MECHANICAL MEASUREMENT OF BIOMATERIAL  
A test device applies a defined mechanical load to a soft biomaterial such as a cell culture and a microscope forms a volume image data set showing the strain field or displacement field occurring...
US20140278134 Conserved Nucleotide Elements In Ribosomal RNA  
The present invention relates to a method of determining conserved ribosomal RNA (rRNA) nucleotide motifs that are specific to one domain of life, Eukarya, Bacteria, or Archaea, and degenerate in...
US20140270435 SPACIAL SEQUENCING/GENE EXPRESSION CAMERA  
Methods, articles and systems that provide imagewise mapping or display of gene expression of a biosample, by contacting the biosample, such as a tissue slice or metacommunity, to a detector which...
8829432 System and methods for determining molecules using mass spectrometry and related techniques  
The present invention generally relates to mass spectrometry and related techniques, and in some cases, to determining single species using mass spectrometry. In certain instances, polymers such...
8822418 Treatment of muscular dystrophies and related disorders  
The invention provides, among other aspects, compositions and methods for treating, preventing, and diagnosing diseases or conditions associated with an abnormal level or activity of biglycan;...
US20140245006 CRYPTOGRAPHIC ACCUMULATORS FOR AUTHENTICATED HASH TABLES  
In one exemplary embodiment, an apparatus includes a memory storing data and a processor performing operations. The apparatus generates or maintains an accumulation tree for the stored data—an...
US20140219486 SYSTEM AND METHOD FOR ENHANCING THE BINAURAL REPRESENTATION FOR HEARING-IMPAIRED SUBJECTS  
A method of enhancing binaural representation for a subject includes receiving a first signal and a second signal in response to a plurality of sound sources, generating a number of estimated...
8795691 Nanotubes and compositions thereof  
The present invention is directed to implants and the modification of the surface of implants using amino acid or polypeptide functionalized rosette nanotubes.
US20140213523 BIGLYCAN VARIANT POLYPEPTIDES AND METHODS OF USE  
The invention provides compositions and methods for treating, preventing, and diagnosing diseases or conditions associated with an abnormal level or activity of biglycan; disorders associated with...
US20140203558 KINETIC ENERGY HARVESTING USING CYBER-PHYSICAL SYSTEMS  
The present invention provides a system for engaging a fluid flow. The system comprising one or more foil members operationally connected to a feedback control loop system. In one embodiment, the...
8776802 Methods and systems for prolonged localization of drug delivery  
An effective method for prolonging localization of therapeutics within the rat gastrointestinal tract of at least about 12 hours is provided. Attractive forces between an orally administered...
US20140182668 HIGH EFFICIENCY SILICON-COMPATIBLE PHOTODETECTORS BASED ON GE QUANTUM DOTS AND GE/SI HETERO-NANOWIRES  
The present disclosure focuses on Ge nanostructured materials for optoelectronic devices: including high-efficiency quantum dot (QD) photodetectors and Si and Ge heteronanowire solar cells. The...
US20140178348 Methods using DNA methylation for identifying a cell or a mixture of cells for prognosis and diagnosis of diseases, and for cell remediation therapies  
Methods using DNA Methylation arrays are provided for identifying a cell or mixture of cells and for quantification of alterations in distribution of cells in blood or in tissues, and for...
US20140172377 METHOD TO RECONSTRUCT A SURFACE FROM ORIENTED 3-D POINTS  
A method for the problem of reconstructing a watertight surface defined by an implicit equation from a finite set of oriented points. As in other surface reconstruction approaches disctretizations...
US20140171482 Nanotubes as Carriers of Nucleic Acids into Cells  
The present invention is directed to transfection complexes of rosette nanotubes and one or more nucleic acids.
US20140166992 SYSTEM AND METHOD FOR A FLEXIBLE DISPLAY ENCAPSULATION  
Provided is an OLED device that is rollable and has a rollable protective covering to protect the OLED when rolled. The rollable protective covering may include a single layer barrier and a...
US20140132357 Broadband Distributed Transmission Line N-Path Filter  
In an embodiment, a single-ended transmission line N-path filter includes one or more filter stages, each stage having a first series inductive element, a shunt N-path filter, and a second series...
8726034 Cryptographic accumulators for authenticated hash tables  
In one exemplary embodiment, an apparatus includes a memory storing data and a processor performing operations. The apparatus generates or maintains an accumulation tree for the stored data—an...
8723509 Electromagnetic position and orientation sensing system  
Magnetic tracking systems and methods for determining the position and orientation of a remote object. A magnetic tracking system includes a stationary transmitter for establishing a reference...
US20140111241 OPTICAL TESTING OF A MULTI QUANTUM WELL SEMICONDUCTOR DEVICE  
A pump light pulse is generating a strain pulse in a sample that includes quantum wells. A signal is measured using a probe light pulse. The probe light pulse is delayed in relation to the pump...
US20140105242 Device and methods for temperature and humidity measurements using a nanocomposite film sensor  
Devices and methods are provided for a nanocomposite having a phase change polymer matrix and conductive nanoparticles to provide greatly enhanced responsivity to temperature and/or humidity. A...
8691766 Biglycan and related therapeutics and methods of use  
The invention provides compositions and methods for treating, preventing, and diagnosing diseases or conditions associated with an abnormal level or activity of biglycan; disorders associated with...
US20140094674 IMPLANTABLE WIRELESS NEURAL DEVICE  
Systems and methods for providing an electrical interface to a body are provided. In one embodiment, an implantable module is disclosed, comprising: an implantable electrode array, implantable...
US20140094403 ENOPEPTINS, USES THEREOF, AND METHODS OF SYNTHESIS THERETO  
Provided herein are inventive enopeptin compounds of Formula (I): and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Further provided are methods of...