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Patents and Patent Applications from Brown University


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US20140333614 SYSTEM AND METHOD FOR SIMULATING REALISTIC CLOTHING  
Systems, methods, and computer-readable storage media for simulating realistic clothing. The system generates a clothing deformation model for a clothing type, wherein the clothing deformation...
8883568 Method providing radial addressing of nanowires  
Disclosed is a method to construct a device that includes a plurality of nanowires (NWs) each having a core and at least one shell. The method includes providing a plurality of radially encoded NWs...
US20140327913 SYSTEMS AND METHODS ENABLING HIGH-THROUGHPUT, REAL TIME DETECTION OF ANALYTES  
System and methods for detecting analytes are provided. The system includes a plasmonic interferometer with a first surface having a first and second scattering element and an aperture disposed...
8869992 Lighting apparatus for capturing and stabilizing mercury  
The present invention is a method and material for using a sorbent material to capture and stabilize mercury. The method for using sorbent material to capture and stabilize mercury contains the...
US20140302109 Nanotubes and Compositions Thereof  
The present invention is directed to implants and the modification of the surface of implants using amino acid or polypeptide functionalized rosette nanotubes.
US20140295538 DEVICE AND SYSTEM FOR MECHANICAL MEASUREMENT OF BIOMATERIAL  
A test device applies a defined mechanical load to a soft biomaterial such as a cell culture and a microscope forms a volume image data set showing the strain field or displacement field occurring...
US20140278134 Conserved Nucleotide Elements In Ribosomal RNA  
The present invention relates to a method of determining conserved ribosomal RNA (rRNA) nucleotide motifs that are specific to one domain of life, Eukarya, Bacteria, or Archaea, and degenerate in...
US20140270435 SPACIAL SEQUENCING/GENE EXPRESSION CAMERA  
Methods, articles and systems that provide imagewise mapping or display of gene expression of a biosample, by contacting the biosample, such as a tissue slice or metacommunity, to a detector which...
8829432 System and methods for determining molecules using mass spectrometry and related techniques  
The present invention generally relates to mass spectrometry and related techniques, and in some cases, to determining single species using mass spectrometry. In certain instances, polymers such as...
8822418 Treatment of muscular dystrophies and related disorders  
The invention provides, among other aspects, compositions and methods for treating, preventing, and diagnosing diseases or conditions associated with an abnormal level or activity of biglycan;...
US20140245006 CRYPTOGRAPHIC ACCUMULATORS FOR AUTHENTICATED HASH TABLES  
In one exemplary embodiment, an apparatus includes a memory storing data and a processor performing operations. The apparatus generates or maintains an accumulation tree for the stored data—an o...
8795691 Nanotubes and compositions thereof  
The present invention is directed to implants and the modification of the surface of implants using amino acid or polypeptide functionalized rosette nanotubes.
US20140213523 BIGLYCAN VARIANT POLYPEPTIDES AND METHODS OF USE  
The invention provides compositions and methods for treating, preventing, and diagnosing diseases or conditions associated with an abnormal level or activity of biglycan; disorders associated with...
US20140203558 KINETIC ENERGY HARVESTING USING CYBER-PHYSICAL SYSTEMS  
The present invention provides a system for engaging a fluid flow. The system comprising one or more foil members operationally connected to a feedback control loop system. In one embodiment, the...
8776802 Methods and systems for prolonged localization of drug delivery  
An effective method for prolonging localization of therapeutics within the rat gastrointestinal tract of at least about 12 hours is provided. Attractive forces between an orally administered...
US20140182668 HIGH EFFICIENCY SILICON-COMPATIBLE PHOTODETECTORS BASED ON GE QUANTUM DOTS AND GE/SI HETERO-NANOWIRES  
The present disclosure focuses on Ge nanostructured materials for optoelectronic devices: including high-efficiency quantum dot (QD) photodetectors and Si and Ge heteronanowire solar cells. The...
US20140178348 Methods using DNA methylation for identifying a cell or a mixture of cells for prognosis and diagnosis of diseases, and for cell remediation therapies  
Methods using DNA Methylation arrays are provided for identifying a cell or mixture of cells and for quantification of alterations in distribution of cells in blood or in tissues, and for...
US20140172377 METHOD TO RECONSTRUCT A SURFACE FROM ORIENTED 3-D POINTS  
A method for the problem of reconstructing a watertight surface defined by an implicit equation from a finite set of oriented points. As in other surface reconstruction approaches disctretizations...
US20140171482 Nanotubes as Carriers of Nucleic Acids into Cells  
The present invention is directed to transfection complexes of rosette nanotubes and one or more nucleic acids.
US20140166992 SYSTEM AND METHOD FOR A FLEXIBLE DISPLAY ENCAPSULATION  
Provided is an OLED device that is rollable and has a rollable protective covering to protect the OLED when rolled. The rollable protective covering may include a single layer barrier and a plastic...
US20140132357 Broadband Distributed Transmission Line N-Path Filter  
In an embodiment, a single-ended transmission line N-path filter includes one or more filter stages, each stage having a first series inductive element, a shunt N-path filter, and a second series...
8726034 Cryptographic accumulators for authenticated hash tables  
In one exemplary embodiment, an apparatus includes a memory storing data and a processor performing operations. The apparatus generates or maintains an accumulation tree for the stored data—an o...
8723509 Electromagnetic position and orientation sensing system  
Magnetic tracking systems and methods for determining the position and orientation of a remote object. A magnetic tracking system includes a stationary transmitter for establishing a reference...
US20140111241 OPTICAL TESTING OF A MULTI QUANTUM WELL SEMICONDUCTOR DEVICE  
A pump light pulse is generating a strain pulse in a sample that includes quantum wells. A signal is measured using a probe light pulse. The probe light pulse is delayed in relation to the pump...
US20140105242 Device and methods for temperature and humidity measurements using a nanocomposite film sensor  
Devices and methods are provided for a nanocomposite having a phase change polymer matrix and conductive nanoparticles to provide greatly enhanced responsivity to temperature and/or humidity. A...
8691766 Biglycan and related therapeutics and methods of use  
The invention provides compositions and methods for treating, preventing, and diagnosing diseases or conditions associated with an abnormal level or activity of biglycan; disorders associated with...
US20140094674 IMPLANTABLE WIRELESS NEURAL DEVICE  
Systems and methods for providing an electrical interface to a body are provided. In one embodiment, an implantable module is disclosed, comprising: an implantable electrode array, implantable...
US20140094403 ENOPEPTINS, USES THEREOF, AND METHODS OF SYNTHESIS THERETO  
Provided herein are inventive enopeptin compounds of Formula (I): and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Further provided are methods of...
8685947 Compositions and methods for loop diuretics with consistent bioavailability  
Diuretic bioactivity profiles of phase inversion micronized furosemide and furosemide co-precipitated with Eudragit L100, and mixtures of those formulations with stock furosemide, reduced or...
US20140088069 NOVEL ANTIBACTERIAL COMBINATION THERAPY  
An antibacterial composition is provided including a combination of a β-lactam antibiotic that has a binding affinity for bacterial penicillin-binding protein 2; and a non-antibiotic compound ...
US20140081432 Method and Apparatus for Rehabilitation Using Adapted Video Games  
A participant, engages in healthcare provider prescribed physical rehabilitation exercises utilizing specifically designed controllers, and these exercises are mapped to one or more video game...
US20140078260 METHOD FOR GENERATING AN ARRAY OF 3-D POINTS  
A method that estimates the coordinates of the calibration points in the projector image plane using local homographies obtained from the imaging camera. First, a dense set of correspondences...
US20140078126 LIFETIME OLED DISPLAY  
Light emitting devices including sub-pixels having different numbers of emissive layers are provided. At least one sub-pixel of a first color may include a single emissive layer, and at least one...
US20140077688 LOW IMAGE STICKING OLED DISPLAY  
Devices and fabrication methods thereof are provided which reduce image sticking and/or improve lifetime and performance of blue emissive devices. Each device may include non-common transport...
US20140077164 OLED FABRICATION USING LASER TRANSFER  
Techniques for fabricating organic light emitting devices, and devices fabricating using the disclosed techniques, are provided. In the disclosed techniques, a layer including an emissive material...
US20140077163 VERY HIGH RESOLUTION AMOLED DISPLAY  
OLED displays having a resolution of 300 dpi, 400 dpi, or greater are provided. Devices as disclosed may use one or more transistors, such as metal oxide transistors, which have a leakage current...
8673857 Long term potentiation with cyclic-GluR6 analogs  
This invention discloses CN2097-like compositions that facilitate the induction of long-term potentiation (LTP). In one embodiment the method comprises inducing long-term potentiation in a subject...
8673359 Nanoparticle compositions and methods for improved oral delivery of active agents  
Nanoparticles, compositions, and methods for the improved uptake of active agents are disclosed herein. The compositions contain a monodisperse population of nanoparticles, preferably including an...
US20140054828 ELECTROSPINNING PROCESS FOR MAKING A TEXTILE SUITABLE FOR USE AS A MEDICAL ARTICLE  
The present invention is a bioactive, nanofibrous material construct which is manufactured using a unique electrospinning perfusion methodology. One embodiment provides a nanofibrous biocomposite...
8658596 Biglycan and related therapeutics and methods of use  
The invention provides compositions and methods for treating, preventing, and diagnosing diseases or conditions associated with an abnormal level or activity of biglycan; disorders associated with...
US20140051981 METHOD AND APPARATUS FOR DIAGNOSIS OF TUMOR ACTIVITY USING TUMOR INTERSTITIAL FLUID PRESSURE  
A scanning apparatus, is used to effect multiple images of a tumor in which a contrast agent has been localized as a detectable marker over a selected time to map the change in the imaged marker....
US20140043017 ELECTROMAGNETIC POSITION AND ORIENTATION SENSING SYSTEM  
Magnetic tracking systems and methods for determining the position and orientation of a remote object. A magnetic tracking system includes a stationary transmitter for establishing a reference...
US20140038906 THERAPEUTIC AND DIAGNOSTIC METHODS INVOLVING BIGLYCAN AND UTROPHIN  
The present disclosure provides methods for predicting a patient's response to biglycan therapy for diseases or conditions associated with an abnormal level or activity of biglycan; disorders...
US20140023253 Image Reconstruction from Incomplete Fourier Measurements and Prior Edge Information  
Systems and methods of image reconstruction that can reduce the number of Fourier transform measurements required to obtain an exact or stable reconstruction of target images, using prior edge...
US20130331383 NITROFURAN COMPOUNDS FOR THE TREATMENT OF CANCER AND ANGIOGENESIS  
The invention is directed to the synthesis and use of nitrofuran compounds, especially Nifurtimox, as medicaments to treat cancer, especially neuroblastoma, and to inhibit angiogenesis. The...
US20130325502 SYSTEM AND METHOD FOR PROVIDING SYNDROME-SPECIFIC, WEIGHTED-INCIDENCE TREATMENT REGIMEN RECOMMENDATIONS  
A system and method for guiding the selection of treatment regimens according to locality-specific and patient-specific criteria. The system and method may employ a guidance engine that determines...
US20130307919 MULTIPLE CAMERA VIDEO CONFERENCING METHODS AND APPARATUS  
In some aspects, a multi-camera device to facilitate multiple camera video conferencing is provided. The multi-camera device comprises a plurality of input ports, each configured to receive video...
8572385 System and method for optimal verification of operations on dynamic sets  
A system and method for cryptographically checking the correctness of outsourced set operations performed by an untrusted server over a dynamic collection of sets that are owned (and updated) by a...
8567253 Opto-acoustic methods and apparatus for performing high resolution acoustic imaging and other sample probing and modification operations  
An opto-acoustic transducer assembly includes a substrate; at least one layer of opto-acoustic material coupled to a surface of the substrate, where the at least one layer of opto-acoustic material...
US20130280319 Compositions, methods and kits for therapeutic treatment with wet spun microstructures  
Methods, compositions, systems, devices and kits are provided for preparing and using a multi-layer polymeric microstructure composition for delivering a therapeutic agent to a subject. In various...