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Patents and Patent Applications from Brown University


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US20140245006 CRYPTOGRAPHIC ACCUMULATORS FOR AUTHENTICATED HASH TABLES  
In one exemplary embodiment, an apparatus includes a memory storing data and a processor performing operations. The apparatus generates or maintains an accumulation tree for the stored data—an o...
8795691 Nanotubes and compositions thereof  
The present invention is directed to implants and the modification of the surface of implants using amino acid or polypeptide functionalized rosette nanotubes.
US20140213523 BIGLYCAN VARIANT POLYPEPTIDES AND METHODS OF USE  
The invention provides compositions and methods for treating, preventing, and diagnosing diseases or conditions associated with an abnormal level or activity of biglycan; disorders associated with...
US20140203558 KINETIC ENERGY HARVESTING USING CYBER-PHYSICAL SYSTEMS  
The present invention provides a system for engaging a fluid flow. The system comprising one or more foil members operationally connected to a feedback control loop system. In one embodiment, the...
8776802 Methods and systems for prolonged localization of drug delivery  
An effective method for prolonging localization of therapeutics within the rat gastrointestinal tract of at least about 12 hours is provided. Attractive forces between an orally administered...
US20140182668 HIGH EFFICIENCY SILICON-COMPATIBLE PHOTODETECTORS BASED ON GE QUANTUM DOTS AND GE/SI HETERO-NANOWIRES  
The present disclosure focuses on Ge nanostructured materials for optoelectronic devices: including high-efficiency quantum dot (QD) photodetectors and Si and Ge heteronanowire solar cells. The...
US20140178348 Methods using DNA methylation for identifying a cell or a mixture of cells for prognosis and diagnosis of diseases, and for cell remediation therapies  
Methods using DNA Methylation arrays are provided for identifying a cell or mixture of cells and for quantification of alterations in distribution of cells in blood or in tissues, and for...
US20140172377 METHOD TO RECONSTRUCT A SURFACE FROM ORIENTED 3-D POINTS  
A method for the problem of reconstructing a watertight surface defined by an implicit equation from a finite set of oriented points. As in other surface reconstruction approaches disctretizations...
US20140171482 Nanotubes as Carriers of Nucleic Acids into Cells  
The present invention is directed to transfection complexes of rosette nanotubes and one or more nucleic acids.
US20140132357 Broadband Distributed Transmission Line N-Path Filter  
In an embodiment, a single-ended transmission line N-path filter includes one or more filter stages, each stage having a first series inductive element, a shunt N-path filter, and a second series...
8726034 Cryptographic accumulators for authenticated hash tables  
In one exemplary embodiment, an apparatus includes a memory storing data and a processor performing operations. The apparatus generates or maintains an accumulation tree for the stored data—an o...
8723509 Electromagnetic position and orientation sensing system  
Magnetic tracking systems and methods for determining the position and orientation of a remote object. A magnetic tracking system includes a stationary transmitter for establishing a reference...
US20140111241 OPTICAL TESTING OF A MULTI QUANTUM WELL SEMICONDUCTOR DEVICE  
A pump light pulse is generating a strain pulse in a sample that includes quantum wells. A signal is measured using a probe light pulse. The probe light pulse is delayed in relation to the pump...
US20140105242 Device and methods for temperature and humidity measurements using a nanocomposite film sensor  
Devices and methods are provided for a nanocomposite having a phase change polymer matrix and conductive nanoparticles to provide greatly enhanced responsivity to temperature and/or humidity. A...
8691766 Biglycan and related therapeutics and methods of use  
The invention provides compositions and methods for treating, preventing, and diagnosing diseases or conditions associated with an abnormal level or activity of biglycan; disorders associated with...
US20140094674 IMPLANTABLE WIRELESS NEURAL DEVICE  
Systems and methods for providing an electrical interface to a body are provided. In one embodiment, an implantable module is disclosed, comprising: an implantable electrode array, implantable...
US20140094403 ENOPEPTINS, USES THEREOF, AND METHODS OF SYNTHESIS THERETO  
Provided herein are inventive enopeptin compounds of Formula (I): and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Further provided are methods of...
8685947 Compositions and methods for loop diuretics with consistent bioavailability  
Diuretic bioactivity profiles of phase inversion micronized furosemide and furosemide co-precipitated with Eudragit L100, and mixtures of those formulations with stock furosemide, reduced or...
US20140081432 Method and Apparatus for Rehabilitation Using Adapted Video Games  
A participant, engages in healthcare provider prescribed physical rehabilitation exercises utilizing specifically designed controllers, and these exercises are mapped to one or more video game...
US20140078260 METHOD FOR GENERATING AN ARRAY OF 3-D POINTS  
A method that estimates the coordinates of the calibration points in the projector image plane using local homographies obtained from the imaging camera. First, a dense set of correspondences...
8673857 Long term potentiation with cyclic-GluR6 analogs  
This invention discloses CN2097-like compositions that facilitate the induction of long-term potentiation (LTP). In one embodiment the method comprises inducing long-term potentiation in a subject...
8673359 Nanoparticle compositions and methods for improved oral delivery of active agents  
Nanoparticles, compositions, and methods for the improved uptake of active agents are disclosed herein. The compositions contain a monodisperse population of nanoparticles, preferably including an...
8658596 Biglycan and related therapeutics and methods of use  
The invention provides compositions and methods for treating, preventing, and diagnosing diseases or conditions associated with an abnormal level or activity of biglycan; disorders associated with...
US20140043017 ELECTROMAGNETIC POSITION AND ORIENTATION SENSING SYSTEM  
Magnetic tracking systems and methods for determining the position and orientation of a remote object. A magnetic tracking system includes a stationary transmitter for establishing a reference...
US20140038906 THERAPEUTIC AND DIAGNOSTIC METHODS INVOLVING BIGLYCAN AND UTROPHIN  
The present disclosure provides methods for predicting a patient's response to biglycan therapy for diseases or conditions associated with an abnormal level or activity of biglycan; disorders...
US20140023253 Image Reconstruction from Incomplete Fourier Measurements and Prior Edge Information  
Systems and methods of image reconstruction that can reduce the number of Fourier transform measurements required to obtain an exact or stable reconstruction of target images, using prior edge...
US20130331383 NITROFURAN COMPOUNDS FOR THE TREATMENT OF CANCER AND ANGIOGENESIS  
The invention is directed to the synthesis and use of nitrofuran compounds, especially Nifurtimox, as medicaments to treat cancer, especially neuroblastoma, and to inhibit angiogenesis. The...
US20130307919 MULTIPLE CAMERA VIDEO CONFERENCING METHODS AND APPARATUS  
In some aspects, a multi-camera device to facilitate multiple camera video conferencing is provided. The multi-camera device comprises a plurality of input ports, each configured to receive video...
8572385 System and method for optimal verification of operations on dynamic sets  
A system and method for cryptographically checking the correctness of outsourced set operations performed by an untrusted server over a dynamic collection of sets that are owned (and updated) by a...
8567253 Opto-acoustic methods and apparatus for performing high resolution acoustic imaging and other sample probing and modification operations  
An opto-acoustic transducer assembly includes a substrate; at least one layer of opto-acoustic material coupled to a surface of the substrate, where the at least one layer of opto-acoustic material...
US20130280319 Compositions, methods and kits for therapeutic treatment with wet spun microstructures  
Methods, compositions, systems, devices and kits are provided for preparing and using a multi-layer polymeric microstructure composition for delivering a therapeutic agent to a subject. In various...
US20130270995 LIGHTING APPARATUS FOR CAPTURING AND STABILIZING MERCURY  
The present invention is a method and material for using a sorbent material to capture and stabilize mercury. The method for using sorbent material to capture and stabilize mercury contains the...
US20130261490 Methods for Prediction and Early Detection of Neurological Events  
Several methods for prediction and detection of neurological events are proposed based on spatiotemporal patterns in recorded neural signals. The methods are illustrated with examples from neural...
US20130249908 PARAMETERIZED MODEL OF 2D ARTICULATED HUMAN SHAPE  
A novel “contour person” (CP) model of the human body is proposed that has the expressive power of a detailed 3D model and the computational benefits of a simple 20 part-based model. The CP mod...
US20130244123 BIOCATHODE-PHOTOANODE DEVICE AND METHOD OF MANUFACTURE AND USE  
A system for harvesting electric energy from illumination by photons by photo- and bioelectrocatalysis includes an electrode coated with conducting polymer matrix containing the oxidoreductase,...
8537363 Picosecond ultrasonic system incorporating an optical cavity  
A method for characterizing a sample is described. The method includes applying a first pulse of electromagnetic radiation to the surface of the sample and thus creating a propagating strain pulse...
8535883 Methods of detecting sources of microorganism contamination  
Methods of detecting a source of a microbial contamination in a suspect sample include detecting at least one member selected from the group consisting of a microbial geosmin synthase, a microbial...
US20130236815 Multimetallic nanoparticle catalysts with enhanced electrooxidation  
A new structure-control strategy to optimize nanoparticle catalysis is provided. The presence of Au in FePtAu facilitates FePt structure transformation from chemically disordered face centered...
US20130236523 Antipathogenic Surfaces Having Selenium Nanoclusters  
The present invention is directed to methods for inhibiting growth of pathogens and to substrates with selenium nanoparticles or selenium nanoclusters having antipathogenic properties.
US20130233700 SYSTEM AND METHODS FOR DETERMINING MOLECULES USING MASS SPECTROMETRY AND RELATED TECHNIQUES  
The present invention generally relates to mass spectrometry and related techniques, and in some cases, to determining single species using mass spectrometry. In certain instances, polymers such as...
US20130231276 Combination Of An Aminoacyl-tRNA Synthetase Inhibitor With A Further Antibacterial Agent For Attenuating Multiple Drug Resistance  
Bacterial multidrug resistance is attenuated in a subject by administering an aminoacyl-tRNA synthetase inhibitor and an antibacterial agent to the subject, wherein the aminoacyl-tRNA synthetase...
US20130228522 ARSENIC REMOVAL SYSTEM  
A system is provided for removing arsenic from water to safe levels at or below the EPA standards. The system is a hybrid spouted vessel/fixed bed filter system that significantly enhances/improves...
8527444 Gap reduction techniques for stochastic optimization using one-step anticipatory algorithm  
In one exemplary embodiment of the invention, a method includes: receiving, by an input, input data descriptive of a stochastic scheduling optimization problem; generating, by a processor, at least...
8524829 Methods for micronization of hydrophobic drugs  
The invention involves methods and products related to the micronization of hydrophobic drugs. A method of micronizing hydrophobic drugs using a set of solutions including an aqueous solution is...
8515145 Methods and apparatus for identifying subject matter in view data  
In one aspect, a method and apparatus for detecting subject matter of interest in view data obtained by scanning an object including generating a filter adapted to respond to the subject matter of...
US20130209683 Methods of Making Nanowires  
The present invention is directed towards methods for growing diamond nanowires via chemical vapor deposition and apparatuses that incorporate these diamond nanowires.
8506923 Nanostructured sorbent materials for capturing environmental mercury vapor  
The present invention is a method and material for using a sorbent material to capture and stabilize mercury. The method for using sorbent material to capture and stabilize mercury contains the...
US20130199539 Nanostructured Surfaces  
The present invention is directed to methods for inhibiting growth of bacteria and to nanometer scale surfaces having antibacterial properties.
8501476 Assays and methods for fusing cell aggregates to form proto-tissues  
Provided are assays and methods for creating proto-tissues from aggregates of cells. The invention concerns assays and methods useful in tissue engineering and reconstruction techniques,...
US20130198854 APPARATUS, METHODS, AND COMPUTER PROGRAM PRODUCTS PROVIDING DYNAMIC PROVABLE DATA POSSESSION  
In one exemplary embodiment, a method includes: storing data for a file, organized as blocks, each having a portion of the file; and maintaining a skip list for the data. The skip list is an...