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5141943 |
5-benzyl barbiturate derivatives
5-benzyl barbiturate compounds for use as water-soluble uridine phosphorylase inhibitors are disclosed. These compounds are useful for reducing the toxicity and anemia induced by antiviral drugs...
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5106627 |
Neurological therapy devices
Neurological therapy devices are disclosed for the local and controlled delivery of a neurotransmitter to the brain of a subject suffering from neurotransmitter deficiency or dysfunction. In one...
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5092871 |
Electrically-charged nerve guidance channels
A medical device is disclosed for use in regenerating a severed nerve, including a tubular, biocompatible, electrically-charged membrane or guidance channel, having openings adapted to receive the...
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5077280 |
Treatment of viral infections
Treatments for viral infections are disclosed based on the finding that uridine can selectively protect and/or rescue uninfected cells, particularly human bone marrow progenitor cells, from the...
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5030225 |
Electrically-charged nerve guidance channels
A medical device is disclosed for use in regenerating a severed nerve. The device includes an implantable, tubular, electrically-charged membrane having openings adapted to receive the ends of the...
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5011486 |
Composite nerve guidance channels
Medical devices and methods employing biocompatible polymers and nerve growth-enhancing active factors are disclosed for use as guidance channels for regenerating nerves. The devices are formed...
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5011472 |
Implantable delivery system for biological factors
Devices and methods are disclosed to provide hybrid, modular systems for the constitutive delivery of appropriate dosages of active factor to a subject and, in some instances, to specific...
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4937187 |
Methods for separating malignant cells from clinical specimens
Fragments of a biopsy sample on the order of about 50 to 5000 cells are preferred for establishing viable tumor cell cultures for purposes such as establishing cell lines, chemotherapeutic assays...
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4911810 |
Modular sputtering apparatus
A sputtering apparatus is constructed in modular form to facilitate changes in sputtering processes and target materials. At least two sputtering modules and a pumping stack module are arranged in...
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4892538 |
In vivo delivery of neurotransmitters by implanted, encapsulated cells
Methods and devices are disclosed for the delivery of a neurotransmitter from an implanted, neurotransmitter-secreting cell culture to a target region in a subject. The cell culture is maintained...
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4878717 |
Apparatus and method for rapidly constructing holograms
An apparatus for constructing a hologram of one or more two-dimensional images by displaying the images on a variable-reflectance device. An object beam of coherent radiation is directed at the...
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4877029 |
Semipermeable nerve guidance channels
Medical devices employing semipermeable materials, such as acrylic copolymers, polyurethane isocyanate, and other biocompatible semipermeable polymers, are disclosed for use as guidance channels in...
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4818357 |
Method and apparatus for sputter deposition of a semiconductor homojunction and semiconductor homojunction products created by same
A vacuum chamber is provided for sputter deposition of a semiconductor homojunction. A target made of a semiconductor compound containing at least one non-metallic element is provided. A substrate...
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4751224 |
Treatment of metastasis
A method for reducing the incidence of metastasis in tumor victims without treating the primary tumor per se resides in the administration of forskolin or its analogs which are potent inhibitors of...
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4734372 |
Cell culturing methods and apparatus
A system and protocol for performing cytotoxicity studies including apparatus and methods for culturing the biopsied cells, for providing oxygenated nutrients, for removing cell-waste products, for...
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4727007 |
Holographic devices employing metallic charge-transfer salts
Metallic salts of organic charge-transfer agents, such as TCNQ, TNAP, TCNE and DDQ and their derivatives, can be processed by an electron beam for a variety of useful electronic and optical...
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4710030 |
Optical generator and detector of stress pulses
An optical stress pulse generation and detection system for non-destructively measuring physical properties of a sample, which uses a pump beam having short duration radiation pulses having an...
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4613604 |
Hydroxymethyl derivatives of 5-benzylacyclouridine and 5-benzoyloxybenzylacyclouridine and their use as potentiators for 5-fluoro-2'-deoxyuridine
A compound of the Formula (I): ##STR1## where X is a benzyl group or a benzyloxybenzyl group and pharmaceutical preparations containing the same.
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4613553 |
Processing of metallic charge-transfer salts
Metallic salts of organic charge-transfer agents, such as TCNQ, TNAP, TCNE and DDQ and their derivatives, can be processed by an electron beam for a variety of useful electronic and optical...
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4559299 |
Cytotoxicity assays in cell culturing devices
Methods and devices for assaying the sensitivity of of biopsied cells to therapeutic agents are disclosed. Cells are cultured in artificial organs and then contacted with a fluorogenic substrate...
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4523319 |
Laser tape systems
A laser tape system for use in the resonant cavity of laser consisting of a flexible tape carrying at least one lasing dye and adapted for insertion into the resonant cavity, and a drive mechanism...
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4456013 |
Catheter
A catheter including a support suitable for insertion into a body organ, a transducer carried by the support, the transducer including a flexible piezoelectric polymeric membrane, and a pair of...
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