Patents and Patent Applications from Brigham Young University


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9779184 Scalable multi-user CAD system and apparatus  
A system for scalable multi-user CAD may include a traffic consolidation server consolidating feature edits from CAD workstations editing one or more proximate regions of an engineering object....
9776859 Microscale metallic CNT templated devices and related methods  
A microscale device comprises a patterned forest of vertically grown and aligned carbon nanotubes defining a carbon nanotube forest with the nanotubes having a height defining a thickness of the...
US20170269034 TWO-CHAMBER DUAL-PORE DEVICE  
Provided is a device comprising a channel through and defined by a plurality of layers surrounding the channel, the channel connecting a first and a second chambers separated by the plurality of...
9764375 Friction bit joining of materials using a friction rivet  
A system and method of joining at least two workpieces together using a friction rivet and a friction rivet cap that are friction stirred together after a cutting tip or cutting feature on the...
US20170258963 CATIONIC STEROIDAL ANTIMICROBIAL COMPOSITIONS FOR THE TREATMENT OF DERMAL TISSUE  
This disclosure relates to dermal treatment compositions, such as dermal fillers and tissue glues, and injectable compositions that incorporate one or more cationic steroidal antimicrobials...
9751153 Effort modulation for process control of friction stir operations  
A system and method for making adjustments to output effort from a spindle driver using a multi-stage nested control loop of an active controller to provide constant power to a friction stir zone...
US20170240968 ALLELIC POLYMORPHISMS ASSOCIATED WITH REDUCED RISK FOR ALZHEIMER'S DISEASE  
The present invention provides methods for determining an individual's risk of developing Alzheimer's disease. The methods include collecting a biological sample from an individual; genotyping a...
9742348 Foldable array of three-dimensional panels including functional electrical components  
Embodiments disclosed herein relate to a foldable array of three-dimensional panels, which may include one or more functional electrical components. For instance, the three-dimensional multi-panel...
9739718 Flow-valve diagnostic microfluidic system  
A system for detecting concentration of a target in a solution where sample fluid is passed into a microchannel with wall coated with the receptor that reacts and crosslinks with the target to...
US20170232004 METHODS FOR TREATING FUNGAL INFECTIONS  
Disclosed herein are methods of treating fungal infections in a patient, comprising identifying a patient in need of treatment and administering a therapeutically effective amount of at least one...
US20170219007 NON-PLANAR CLOSED-LOOP HINGE MECHANISM WITH ROLLING-CONTACT HINGE  
A hinged mechanism includes: panels; and hinges connecting respective pairs of the panels to each other in a closed loop so that the hinged mechanism is non-planar, wherein at least one of the...
US20170218616 MOMENT-RESISTING FRAMES, KITS FOR ASSEMBLING THE SAME, AND METHODS OF REPAIRING THE SAME  
Various embodiments disclosed herein relate to moment-resisting frames, kits for assembling such moment-resisting frames, and methods of repairing such moment-resisting frames. In an embodiment, a...
US20170210776 CATIONIC STEROIDAL ANTIMICROBIALS  
Disclosed herein are cationic steroidal antimicrobials (“CSA compounds” or “ceragenins”) and methods of making the same. Particularly advantageous methods are identified for the synthesis of CSA...
9696277 Two-chamber dual-pore device  
Provided is a device comprising a channel through and defined by a plurality of layers surrounding the channel, the channel connecting a first and a second chambers separated by the plurality of...
9694019 Compositions and methods for treating bone diseases and broken bones  
Disclosed herein are methods of promoting osteogenesis in a subject, comprising administering a composition comprising a therapeutically effective amount of at least one cationic steroid...
9686966 Methods and apparatus for cleaning or disinfecting a water delivery system  
Methods for cleaning or disinfecting water delivery systems, self-cleaning or self-disinfecting water delivery systems, and inserts for use in cleaning or disinfecting water delivery systems...
US20170174720 CATIONIC STEROIDAL ANTIMICROBIAL SALTS  
Disclosed herein are acid addition salts of cationic steroidal antimicrobials (“CSAs” or “ceragenins”) and methods of making the same. Particularly advantageous salt forms are identified, such as...
9678046 Gas chromatography using a thermal gradient that is substantially monotonically non-increasing and has a positive second derivative  
A system and method for thermal gradient gas chromatography wherein a front or injection end of a column is heated to a higher temperature than a back or detector end to thereby create a thermal...
US20170152280 SCAPHOPETALONE ANALOGS AND THEIR USES  
The present disclosure relates to scaphopetalone analogs, methods of making the analogs, and their uses.
US20170138964 Systems, Assays, and Methods for Determining Risk Factors for Alzheimer's Disease  
A method of determining risk factors for Alzheimer's disease in an individual, including assaying a biological medium obtained from the individual for a biomarker selected from Biomarker 1,...
US20170137459 HYDROPHOBIC CERAGENIN COMPOUNDS AND DEVICES INCORPORATING SAME  
A hydrophobic cationic steroidal anti-microbial (ceragenin) compound forms an amphiphilic compound having a hydrophobic sterol face and a hydrophilic cationic face. Medical devices can be made...
US20170128489 ORGANO-TRANSITION METAL COMPLEXES FOR THE TREATMENT OF VIRAL INFECTIONS  
Organo-transition metal complexes possess anti-viral inhibitory activity against influenza A, including the S3 IN mutant. The organo-transition metal complexes include a transition metal and at...
9648059 System and methods for multi-user CAx editing conflict management  
A multi-user CAx editing system may comprise a plurality of editing clients and a collaborative editing server. The server and editing clients may be collectively configured to: a) assign a...
9642651 Inverted serpentine spinal stability device and associated methods  
A spinal implant includes a plurality of frame segments that define a first frame array, the first frame array being coupled to a first mounting connection. A plurality of contiguous segments...
US20170121364 HYDROPHOBIC CERAGENIN COMPOUNDS AND DEVICES INCORPORATING SAME  
A hydrophobic cationic steroidal anti-microbial (ceragenin) compound forms an amphiphilic compound having a hydrophobic sterol face and a hydrophilic cationic face. Medical devices can be made...
US20170109120 METHOD FOR PREVENTING REFERENCE INVALIDATION WHEN REVERSING OPERATIONS IN SYNCHRONOUS COLLABORATIVE APPLICATIONS  
A computer-implemented method for preventing reference invalidation when reversing operations in synchronous collaborative applications may include (i) storing, on a client, a shared model of an...
US20170108462 FABRICATION OF HIGH ASPECT RATIO TALL FREE STANDING POSTS USING CARBON-NANOTUBE (CNT) TEMPLATED MICROFABRICATION  
In a general aspect, an apparatus can include a substrate and a post disposed on the substrate. The post can include a plurality of nanotubes and extend substantially vertically from the...
US20170087551 METHOD FOR AMPLIFICATION-FREE NUCLEIC ACID DETECTION ON OPTOFLUIDIC CHIPS  
An optofluidic platform is constructed so as to comprise a planar, liquid-core integrated optical waveguides for specific detection of nucleic acids. Most preferably, the optical waveguides...
9603859 Methods and products for increasing the rate of healing of tissue wounds  
Disclosed are methods for increasing the rate of healing of a tissue wound by administering a composition including a therapeutically effective amount of at least one cationic steroid...
US20170080128 NOVEL ENDOTRACHEAL TUBE FOR THE REDUCTION OF INTUBATION-RELATED COMPLICATION IN NEONATES AND BABIES  
This disclosure relates to medical devices incorporating one or more cationic steroidal antimicrobials (CSAs). The CSAs are incorporated into the medical devices to provide effective...
9581530 Multichannel impact response for material characterization  
A non-destructive test system includes a plurality of impact devices including a knob configured to generate at least one flexural mode in a material when a surface of the material is impacted by...
US20170045449 NONDESTRUCTIVE OPTICAL TESTING SYSTEMS AND RELATED METHODS FOR PREDICTING MATERIAL FAILURE  
Embodiments disclosed herein relate to systems and methods for nondestructive testing of material to predict oncoming failure thereof. For example, components and/or elements of various devices...
US20170035677 ORAL CARE COMPOSITIONS  
Aqueous and substantially non-aqueous oral compositions comprising a cationic steroidal compound are suitable for treating conditions of the oral cavity.
US20170029454 NKT CELL LIGANDS AND METHODS OF USE  
Alpha-glycosylceramide compounds capable of activating NKT cells and compositions thereof are disclosed. Methods for activating NKT cells, methods of stimulating an immune response in a subject,...
9554502 Seed coating compositions and methods for applying soil surfactants to water-repellent soil  
Herein provided are innovative methods and techniques for improving seedling germination and plant establishment including a seed composition of at least one seed having a seed protective coating...
US20170024447 SYSTEM, METHOD, AND APPARATUS FOR COLLABORATIVE EDITING OF COMMON OR RELATED COMPUTER BASED SOFTWARE OUTPUT  
A system includes a collaborative data store that stores an object which can comprise a description, model, representation, arrangement or composition created by one or more contributors, the...
9551667 Method for amplification-free nucleic acid detection on optofluidic chips  
An optofluidic platform is constructed so as to comprise a planar, liquid-core integrated optical waveguides for specific detection of nucleic acids. Most preferably, the optical waveguides...
9546195 Hydrophobic ceragenin compounds and devices incorporating same  
A hydrophobic cationic steroidal anti-microbial (ceragenin) compound forms an amphiphilic compound having a hydrophobic sterol face and a hydrophilic cationic face. The hydrophobic CSA also...
9536453 Computer-implemented communication assistant for the hearing-impaired  
Computing systems are provided for facilitating communication to the hearing-impaired. The computing systems obtain and modify a video that includes a signer performing sign language about a...
9533063 Aerosols incorporating ceragenin compounds and methods of use thereof  
Aerosols that include ceragenin compounds (i.e., ceragenin-containing aerosols), methods for delivering such aerosols, and devices for delivering such aerosols. Ceragenins can be used to kill a...
9527883 Methods for the synthesis of ceragenins  
Disclosed herein are methods of making ceragenin compounds for treating, preventing, or diagnosing diseases, disorders, or conditions associated with bacterial or viral infections, cancer,...
US20160367388 VASCULAR STENTS AND RELATED METHODS  
A vascular stent assembly includes at least a first and a second strut, each including a thickness and a depth. The assembly includes a pair of end radii, with each of the first and second struts...
US20160363549 FLEXIBLE ELEMENTS FOR PROBES AND GUARD RINGS  
In one general aspect, an apparatus can include a probe including an exterior probe element including a first plurality of links defining a first flexible element. The exterior probe element can...
9512618 Rigidly foldable array of three-dimensional bodies  
Rigidly foldable, foldable multi-body arrays or systems that may include three-dimensional bodies connected together by multiple hinges and reconfigurable between unfolded and folded configurations.
9511575 Sonication for improved particle size distribution of core-shell particles  
In one or more embodiments, a porous composite particulate material includes a plurality of composite particles including an acid-base-resistant core particle at least partially surrounded by one...
9502206 Corrosion-resistant, strong x-ray window  
The invention is an x-ray window with a stack of thin film layers including aluminum layer(s), corrosion-barrier layer(s), and/or polymer layer(s). Aluminum layer(s) can provide improved gas...
US20160328572 FRAUDULENT APPLICATION DETECTION SYSTEM AND METHOD OF USE  
The present invention provides a system and a method for detecting or determining a possible fraudulent information provided by a subject using the subject's behavioral biometric during an...
US20160311852 METHODS FOR THE SYNTHESIS OF CERAGENINS  
Disclosed herein are methods of making ceragnenin compounds for treating, preventing, or diagnosing diseases, disorders, or conditions associated with bacterial or viral infections, cancer,...
US20160311851 METHODS FOR THE SYNTHESIS OF CERAGENINS  
Disclosed herein are methods of making ceragnenin compounds for treating, preventing, or diagnosing diseases, disorders, or conditions associated with bacterial or viral infections, cancer,...
US20160311850 CATIONIC STEROIDAL ANTIMICROBIAL SALTS  
Disclosed herein are acid addition salts of cationic steroidal antimicrobials (“CSAs” or “ceragenins”) and methods of making the same. Particularly advantageous salt forms are identified, such as...