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US20120028838 |
Quantification of Gene Expression
The present invention relates to a method for measuring the amount of a target nucleic acid in a sample using a standard which is designed to have one base difference compared with the gene of...
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8093417 |
Lipoxin analogs and methods for the treatment of periodontal disease
This invention provides new lipoxin analogs, compositions containing analogs, and methods of using these compounds and compositions for treating and preventing oral inflammation, including...
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8093288 |
Genipin derivatives and uses thereof
Genipin derivatives and pharmaceutical compositions thereof that inhibit the activity of uncoupling protein-2 (UCP2) and are useful in treating deficient first-phase insulin secretion, non-insulin...
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US20120003630 |
MODULAR NUCLEIC ACID-BASED CIRCUITS FOR COUNTERS, BINARY OPERATIONS, MEMORY, AND LOGIC
We have created novel engineered genetic counter designs and methods of use thereof that utilize DNA recombinases to provide modular systems, termed single invertase memory modules (SIMMs), for...
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US20110313145 |
ISOLATION OF RNA
Disclosed herein are methods for purification of RNA from a sample. The RNA can be total RNA or mRNA. The method involves preparing the sample in a solution of lysis buffer and depositing into a...
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8071282 |
Method of storing red blood cells with an acidic additive solution under oxygen depletion
There is provided compositions and methods for the storage of red blood cells. The compositions are additive solutions comprising adenine, dextrose, mannitol, NaH2PO4, and optionally NaCl and/or...
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US20110285991 |
CHEMICAL/BIOLOGICAL SENSOR EMPLOYING SCATTERED CHROMATIC COMPONENTS IN NANO-PATTERNED APERIODIC SURFACES
A label-free multiplexed sensing platform is based on light interaction with aperiodic photonic structures with an advantage of a broadband operation. Multiple-scattering-induced...
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8063535 |
Nanomechanical oscillator
A mechanical oscillator has components with dimensions in a sub-micron range to produce resonance mode oscillations in a gigahertz range. A major element is coupled to a minor, sub-micron element...
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US20110267614 |
ENGINEERED SERS SUBSTRATES EMPLOYING NANOPARTICLE CLUSTER ARRAYS WITH MULTISCALE SIGNAL ENHANCEMENT
Defined nanoparticle cluster arrays (NCAs) with total lateral dimensions of up to 25.4 μm by 25.4 μm have been fabricated on top of a 10 nm thin gold film using template guided self-assembly. T...
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US20110251149 |
METHODS AND LOW DOSE REGIMENS FOR TREATING RED BLOOD CELL DISORDERS
Disclosed herein are methods and low dose regimens for increasing fetal hemoglobin levels in patients with red blood cell disorders, such as beta thalassemia, sickle cell disease, other anemias, or...
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8035113 |
Optical devices featuring textured semiconductor layers
A semiconductor sensor, solar cell or emitter, or a precursor therefor, has a substrate and one or more textured semiconductor layers deposited onto the substrate. The textured layers enhance light...
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8034567 |
Quantification of gene expression
The present invention relates to a method for measuring the amount of a target nucleic acid in a sample using a standard which is designed to have one base difference compared with the gene of...
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US20110245154 |
Methods and Compositions for Treating Viral or Virally-Induced Conditions
Provided are methods and compositions for the prevention and/or treatment of viral conditions, virally-induced conditions and inflammatory conditions. The methods can comprise administering to a...
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US20110244451 |
Methods for prenatal diagnosis of chromosomal abnormalities
Chromosomal abnormalities are responsible for a significant number of birth defects, including mental retardation. The present invention is related to methods for non-invasive and rapid, prenatal...
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US20110243883 |
POLYMERIC BIOLUBRICANTS FOR MEDICAL USE
The present invention provides branched polymers which can be used as lubricants or shock absorbers in vivo. For example, the inventive polymers can be used as viscosupplements, viscoelastics,...
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US20110237654 |
METHOD TO INHIBIT CELL GROWTH USING OLIGONUCLEOTIDES
Described are methods for treating hyperproliferative disorders, including cancers, by administering to the affected mammal (e.g., human) an effective amount of a composition comprising one or more...
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US20110236966 |
SINGLE LENTIVIRAL VECTOR SYSTEM FOR INDUCED PLURIPOTENT (IPS) STEM CELLS DERIVATION
The present invention is based on the discovery that a single lentiviral vector expressing multiple individual transcription factor proteins from a single multi-cistronic mRNA can reprogram a...
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US20110217328 |
COMPOSITIONS AND METHODS FOR TREATING EBOLA VIRUS INFECTION
The compositions and methods of the invention described herein provide treatments against Ebola virus infection by expressing gene(s) from the Ivory Coast ebolavirus (ICEBOV) species in a...
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US20110207679 |
METHODS OF TREATMENT USING IL-16 ANTAGONIST PEPTIDES
The present invention has found that a series of peptides having sequences that substantially correspond to specific regions of the C-terminus of IL-16 can inhibit the activity of IL-16. The...
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US20110201667 |
COMPOSITIONS AND METHODS FOR SILENCING EBOLA VIRUS GENE EXPRESSION
The present invention provides compositions comprising therapeutic nucleic acids (e.g., interfering RNA such as siRNA) that target Ebola virus (EBOV) gene expression and methods of using such...
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7999095 |
Nucleic acid supported protein complementation
The present invention is directed to novel methods for in vitro and in vivo detection of target nucleic acid molecules, including DNA and RNA targets, as well as nucleic acid analogues. The present...
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US20110191871 |
METHODS TO IDENTIFY FACTORS ASSOCIATED WITH MUSCLE GROWTH AND USES THEREOF
The present invention relates to methods to identify factors associated with muscle growth, angiogenesis, obesity, insulin sensitivity body weight, fat mass, muscle mass and cardiovascular...
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US20110187297 |
SWITCHING DEVICES AND RELATED METHODS
A mechanical device capable of switching between two states is described. The device may include a micromechanical resonator with two distinct states in the hysteretic nonlinear regime. The devices...
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US20110177534 |
DIAGNOSTICS FOR MEMBRANOUS NEPHROPATHY
The invention relates to immunoassays, reagents, therapeutics and methods of diagnosing and prognosis evaluation of idiopathic membranous nephropathy (MN). Immunoassays comprise enzyme-linked...
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US20110172785 |
COMPLIANT COMPOSITES FOR APPLICATION OF DRUG-ELUTING COATINGS TO TISSUE SURFACES
A compliant composite for delivering a bioactive agent including a scaffolding material and a polymer coating that together can be attached to compliant tissue surfaces is disclosed, along with...
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US20110172753 |
ENDOPROSTHESES
Endoprosthesis are disclosed.
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7976936 |
Endoprostheses
Endoprostheses are disclosed.
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US20110158909 |
Cationic Contrast Agents and Methods of Use Thereof
The present invention provides compounds useful as contrast agents, such as for the CT imaging of cartilage tissue. The contrast agents are generally iodinated organic molecules that are positively...
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US20110152305 |
FILMS AND PARTICLES
Described herein are compounds and processes that can be used to prepare polymer-based films, particles, gels and related compositions, and processes for delivery of agents, and other uses.
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US20110142821 |
ROLES FOR DUAL ENDOTHELIN-1/ANGIOTENSIN II RECEPTOR (DEAR) IN HYPERTENSION AND ANGIOGENESIS
The present application is directed to the identification of mutations and/or polymorphisms in the Dual Endothelin-1/Angiotensin II Receptor (Dear) that indicate susceptibility to, or show current...
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US20110135716 |
DELIVERY OF H2 ANTAGONISTS
The present invention provides improved systems and methods for the local delivery of H2 antagonists. The inventive methods include topical administration of an effective amount of a H2 antagonist...
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US20110129878 |
BIOREACTIVE AGENTS
This invention relates to agents and conjugates that can be used to detect and isolate target components from complex mixtures such as nucleic acids from biological samples, cells from bodily...
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US20110123526 |
METHODS AND COMPOSITIONS FOR PREVENTING ADHESION
This invention provides methods and compositions for preventing post-surgical adhesion formation based on use of an interleukin-16 (IL-16) antagonist, including an IL-16 antagonist peptide and/or...
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US20110119259 |
NETWORK BIOLOGY APPROACH FOR IDENTIFYING TARGETS FOR COMBINATION THERAPIES
Described herein is a network biology approach useful for the identification of multiple therapeutic targets, which can be targeted simultaneously using an agent (or a plurality of agents) to...
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US20110109736 |
System and Method for Producing an Optically Sectioned Image Using Both Structured and Uniform Illumination
A first image data set of the real-world object is received at a processor where the real-world object was illuminated with substantially uniform illumination. A second image data set of the...
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US20110106049 |
FULLY AUTOMATED CONTROL SYSTEM FOR TYPE 1 DIABETES
An augmented, adaptive algorithm utilizing model predictive control (MPC) is developed for closed-loop glucose control in type 1 diabetes. A linear empirical input-output subject model is used with...
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US20110098678 |
MANIPULATORS EMPLOYING MULTIPLE DEFORMABLE ELONGATE MEMBERS
A manipulator is configured with a set of substantially concentric, elongate members configured such that relative rotation and translation of the elongate members adjusts both the spatial position...
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US20110097721 |
IN VIVO GENE SENSORS
Described are methods and compositions for the detection of target genes. The inventors have developed a synthetic nucleic acid sensor-effector gene circuit. In cells without a target gene, the...
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US20110097712 |
METHOD FOR DETECTING AND QUANTIFYING RARE MUTATIONS/POLYMORPHISMS
The present invention is directed to a method for detecting and quantifying rare mutations in a nucleic acid sample. The nucleic acid molecules under investigation can be either DNA or RNA. The...
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US20110091487 |
MELANOMA BIOMARKER AND METHODS OF USES
The present invention relates to the use of TROY, also called tumor necrosis factor receptor superfamily, member 19 (TNFRSF19) also called toxicity and JNK inducer (TAJ), in diagnosis and therapy...
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7929195 |
MEMS based retroreflector
A deformable reflective surface is disclosed that may be used with a retroreflector to provide a modulated retroreflector. The modulated retroreflector may be used in communication systems such as...
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US20110086869 |
METHODS FOR TREATING VIRAL DISORDERS
Disclosed are methods of treating viral disorders via the administration of an inducing agent and an anti-viral agent. In one embodiment, the inducing agent and the anti-viral agent are...
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7919093 |
Roles for dual endothelin-1/angiotensin II receptor (Dear) in hypertension and angiogenesis
The present application is directed to the identification of mutations and/or polymorphisms in the Dual Endothelin-1/Angiotensin II Receptor (Dear) that indicate susceptibility to, or show current...
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7914778 |
Methods of treatment using IL-16 antagonist peptides
The present invention has found that a series of peptides having sequences that substantially correspond to specific regions of the C-terminus of IL-16 can inhibit the activity of IL-16. The...
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US20110068834 |
ELECTRO-MECHANICAL OSCILLATING DEVICES AND ASSOCIATED METHODS
Electro-mechanical oscillating devices designed to convert the frequency of electrical signal(s) and methods associated with the same are described. One example of such a frequency converting...
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7910624 |
Compositions for the treatment of blood disorders
The invention relates to compositions containing chemical compounds and compositions containing steel factor which stimulate the expression of hemoglobin or globin protein such as embryonic or...
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US20110064677 |
LIPOXIN ANALOGS AND METHODS FOR THE TREATMENT OF PERIODONTAL DISEASE
This invention provides new lipoxin analogs, compositions containing analogs, and methods of using these compounds and compositions for treating and preventing oral inflammation, including...
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US20110060188 |
LOW COST DISPOSABLE MEDICAL FORCEPS TO ENABLE A HOLLOW CENTRAL CHANNEL FOR VARIOUS FUNCTIONALITIES
The present invention relates to an endoscopic biopsy forceps (10) with an open central channel. The forceps include a sheath (20) having a proximal end and a distal end, a housing (50) connected...
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7903246 |
Deterministic aperiodic patterned dielectric and plasmonic materials for localized electromagnetic field enhancement
A method is shown for the extension in higher spatial dimensions of deterministic, aperiodic structures which exhibit strong aperiodic effects and have overall compatibility with the planar...
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US20110053284 |
CHEMICAL FUNCTIONALIZATION OF SOLID-STATE NANOPORES AND NANOPORE ARRAYS AND APPLICATIONS THEREOF
Chemical functionalization of solid-state nanopores and nanopore arrays and applications thereof. Nanopores are extremely sensitive single-molecule sensors. Recently, electron beams have been used...
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