Patents and Patent Applications from Boston University Boston Medical Center


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4818687 Affinity column and process for detection of low molecular weight toxic substances  
An affinity matrix and a method for the detection of low molecular weight compositions such as aflatoxins are provided utilizing specific monoclonal IgM antibody having an affinity constant not...
4816437 Methods for inducing general and localized bone apposition in-vivo  
The present invention provides unique methodologies for inducing new bone apposition in-vivo generally or at a localized site and for therapeutically treating a subject afflicted with a...
4803736 Neural networks for machine vision  
Network interactions within a Boundary Contour (BC) System, a Feature Contour (FC) System, and an Object Recognition (OR) System are employed to provide a computer vision system capable of...
4802951 Method for parallel fabrication of nanometer scale multi-device structures  
Articles exhibiting fabricated structures with nanometer size scale features (nanostructures), typically a device comprising nanostructures of a functional material on or in a substrate of...
4797889 Solid state molecular laser  
A solid state laser in which molecules containing transition metal ions form the lasing medium. More particularly, the electronic states of molecular complexes containing transition metal ions,...
4786277 Electrodes, electrode assemblies, methods, and systems for tissue stimulation  
A novel electrode and electrode assembly is provided which preferably uses alternating and direct electrical energy for transdermal delivery of pharmacologically active ligands and for stimulation...
4778787 Method for treatment of angina and myocardial infarctions with omental lipids  
Angiogenesis healing factors residing in omentum-derived lipid fractions with or without gangliosides or their synthetic equivalents can be used to treat myocardial ischemic conditions including...
4769362 Increased vascular perfusion following administration of lipids  
Lipid containing molecules and compositions, including gangliosides and omental tissue extracts had previously been found to be effective in increasing angiogenesis. It has now been found that...
4767746 Method for enhancement of healing of epithelial wounds in mammals  
Omental lipid fractions accelerate wound healing especially as to epithelialization in mammals.
4766111 Lipids with plasmin inhibitory properties  
Plasmin inhibitory substances have been found in mammalian omental extracts. The substances all contain lipid components. In addition, related commercially available lipid containing molecules,...
4762820 Therapeutic treatment for congestive heart failure  
A novel therapeutic method for treating human and animal subjects afflicted with congestive heart failure is provided by administering effective dosages of a selective antagonist for arginine...
4762600 Partially reduced ferric oxide catalyst for the making of ammonia via the photassisted reduction of molecular nitrogen  
A novel, activated catalyst is provided for the synthesis of ammonia via the photoassisted reduction of molecular nitrogen by water. The novel catalyst is an incompletely reoxidized hydrogen...
4760019 Antigenic preparation and diagnostic method for identification of nocardia infections  
A novel antigenic preparation and unique diagnostic methodology for the detection of human Nocardiosis is provided which is rapid, sensitive, and reproducibly accurate in providing empirical...
4728591 Self-assembled nanometer lithographic masks and templates and method for parallel fabrication of nanometer scale multi-device structures  
Articles exhibiting fabricated structures with nanometer size scale features (nanostructures), typically a device comprising nanostructures of a functional material on or in a substrate of...
4716111 Process for producing human antibodies  
Human antibodies are provided by collecting the mononuclear cells from human blood, removing suppressor T-cells and exposing the remaining lymphocyte cells to an antigen, autologous serum of the...
4710490 Compositions containing ganglioside molecules with enhanced angiogenic activity  
Compositions which contain lipid containing molecules possessing angiogenic activity are disclosed. The lipid containing molecules have been found in mammalian tissue, particularly the omentum, of...
4703030 Partially reduced ferric oxide catalyst for the making of ammonia via the photoassisted reduction of molecular nitrogen and method for the preparation of the catalyst  
A novel, activated catalyst is provided for the synthesis of ammonia via the photoassisted reduction of molecular nitrogen by water. The novel catalyst is an incompletely reoxidized hydrogen...
4702732 Electrodes, electrode assemblies, methods, and systems for tissue stimulation and transdermal delivery of pharmacologically active ligands  
A novel electrode and electrode assembly is provided which preferably uses alternating and direct electrical energy for transdermal delivery of pharmacologically active ligands and for stimulation...
4701521 Method of effecting cellular uptake of molecules  
A method of effecting cellular uptake of molecules which are either excluded from cells or poorly transported into cells is disclosed wherein such molecules are covalently bonded to a cationic...
4701406 Assay for the detection of epigenetic toxic (non-genotoxic) substances  
An in vitro assay procedure for the detection of non-genotoxic substances is provided which utilizes a prepared cell culture whose cytoskeleton constituents are structurally identifiable as...
4699788 Angiogenic factor methods of extraction and method for producing angiogenesis  
A novel angiogenic composition obtained from the omentum is provided which acts as a potent and effective factor for blood perfusion enhancement and for the development of new blood vessels in an...
4680382 Analogues of actinomycin D  
Analogues of actinomycin D are provided which are effective in the therapeutic treatment of cancer. The analogues have the formulas: ##STR1##
4673667 Lipids with plasmin inhibitory properties  
Plasmin inhibitory substances have been found in mammalian omental extracts. The substances all contain lipid components. In addition, related commercially available lipid containing molecules,...
4645340 Optically reflective sphere for efficient collection of Raman scattered light  
A device for the collection of Raman scattered light by means of an internally reflective sphere 10 wherein a light source 12 provides light to and through a sample 16, which light is reflected...
4612096 Method for making ammonia by the reduction of molecular nitrogen  
A novel method of producing ammonia by the reduction of molecular nitrogen is provided using a solid metal oxide catalyst and an organic compound in aqueous medium. Pure gaseous nitrogen or air can...
4608869 Single particle detection system  
In order to identify the density of a particle, an acoustic wave is focused on the particle and the reflected wave is detected by the focusing transducer. The ratio of the Fourier transform of the...
4576948 Composition and method for inhibiting terminal deoxyribonucleotidyl transferase activity  
New uracil compounds having the formula: ##STR1## wherein X is C1 -C10 alkoxy or amino are provided. These compounds are useful in treating patients having leukemia, the cells of which express...
4573778 Aqueous fluorophotometer  
Fluorescence of the anterior chamber of an eye is determined by projecting a ribbon of light from the side of the eye through the anterior chamber in a direction generally perpendicular to the...
4569354 Method and apparatus for measuring natural retinal fluorescence  
Oxygenation of the retina is determined by measuring the fluorescence of flavoprotein in the retina. A spot of excitation light of a frequency of about 450 nanometers is scanned across the retina....
4565784 Hydrogels capable of supporting cell growth  
A method of growing anchorage-dependent cells is disclosed in which a substrate comprising a hydrogel is employed. The hydrogel is formed from an aqueous solution gelled with a crosslinked polymer...
4537712 Non-specific suppressive factors and process  
A high purity immunosuppression factor (IF) having a molecular weight of about 50,000 or a reduced IF having a molecular weight of about 25,000 derived from the higher molecular weight IF and which...
4514330 Carbon-7-substituted atinomycin D analogue  
7-(2,3-Epoxypropoxy)actinomycin D has been synthesized along with its major companion product, 7-(2,3-dihydroxypropoxy)-actinomycin D. They were characterized by UV-visible and CD spectra and by...
4500524 Tranquilizing and reducing or preventing seizures  
Seizures are inhibited or prevented and tranquilizing effect induced by administering riboflavin or a riboflavin analog, alone or in combination with a conventional anticonvulsant or tranquilizer...
4474876 Flow cytometric analysis of histamine receptors  
A method for analyzing cells to determine whether they have substantial numbers of H1 and H2 histamine receptors. Also an assay kit and a composition for conducting such analyses. The assays...
4448150 Animal housing and activity monitor  
An animal activity housing and monitor includes several vertically displaced levels of animal cages 32 which are angularly disposed about a core 28. The core is mounted for rotation relative to the...
4403939 Process and apparatus for producing a molecularly oriented film  
Apparatus for forming a film of uniformly oriented molecules from a solution or suspension of the molecules including means to house the molecules in a swinging bucket centrifugation apparatus. The...
4367406 Cylindrical mirror electrostatic energy analyzer free of third-order angular aberrations  
A cylindrical mirror electron spectrometer includes an additional electrode between the usual inner and outer cylinders. The additional electrode is maintained at a potential slightly more negative...
4314550 Method of treating an arrested heart  
A heart in induced arrest such as ischemic arrest during a surgical operation is treated to protect it from stiffness, rigor, contracture and a decrease in diastolic compliance or elasticity by...
4262066 Sunlight rechargeable storage cell  
In a rechargeable storage cell, the photoredox reaction and regenerating reaction of a photoredox couple in one half-cell provide the driving force for producing charged state redox couples in both...
4249825 Method and apparatus suitable for ocular blood flow analysis  
Glaucoma and other diseases may be detected by the analysis of angiograms to determine ocular blood flow. Using rapid sequence photography an ocular image is recorded on successive film frames. To...
4241005 Process for producing a molecularly oriented film  
Films having uniformly oriented molecules or molecular structures are formed by centrifuging a suspension or solution of molecules or molecular structures onto a gravitational isopotential surface...
4225233 Rapid scan spectrophotometer  
A spectrometer capable of providing a predetermined wavelength of output light in accordance with a control voltage signal applied to a scanning element is described. The scanning element located...
4190628 Kit for determining the level of LDL cholesterol in body fluids  
A kit for determining the level of LDL cholesterol in body fluids is disclosed which contains a plant lectin which is a specific agglutinating agent for LDL.
4126416 Method for determining the level of LDL cholesterol in blood plasma  
A method for determining the level of LDL cholesterol in blood plasma wherein LDL cholesterol is separated from other soluble cholesterol fractions by selectively agglutinating LDL with a plant...
4052536 Electrolytes which are useful in solar energy conversion  
Electrolytes are disclosed which are useful in solar energy conversion and which have a wider range of wavelength response and enhanced activity compared to the photoredox system contained therein....
T958011 Objective focusing method and apparatus for fundus photography  
apparatus and method for objectively focusing an instrument used for photographing the fundus of the eye such that consistent high resolution fundus photographs can be attained.A narrow sharp...
4014097 Method and apparatus for measuring and recording three-dimensional condylermovements of the mandible  
A dentistry aid is comprised by a recording system which is concerned with occlusion and related movements of the condyles in the tempero mandibular joints of a patient. Condyle movement, occurring...