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4871350 |
Methods and compositions for preventing secondary cataracts
Novel methods and compositions are provided for preventing secondary cataracts. A cytotoxic agent is employed which is introduced into the anterior chamber of the eye to inhibit proliferation of...
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4824667 |
Thymidine kinase deletion mutants of bovine herpesvirus-1, vaccines against infectious bovine rhinotracheitis containing same and methods for the production and use of same
Bovine herpesvirus type 1 (infectious bovine rhinotracheitis virus) mutants which fail to produce any functional thymidine kinase as a result of a deletion in the thymidine kinase gene. The...
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4822736 |
Amplification of adenosine deaminase genes in mammalian cells using adenosine, alanosine, uridine, and deoxycoformycin
Disclosed are cultured mouse cells with amplified adenosine deaminase genes which greatly overproduce adenosine deaminase. The cells were isolated by growth in media containing alanosine, uridine,...
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4822470 |
Method of and apparatus for cell poration and cell fusion using radiofrequency electrical pulses
Disclosed are an apparatus and a method for the poration and fusion of cells using radiofrequency electrical pulses. The electrodes of the apparatus can be hand held or part of integrated equipment...
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4795463 |
Labeled breast prosthesis and methods for detecting and predicting rupture of the prosthesis
Disclosed is a prosthesis for implantation into human soft tissue which is constructed of a suitable implantable envelope and contents to form a breast shape when implanted, such as silicone gel,...
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4781192 |
Balloon dilation apparatus
Disclosed is an improved and simplified apparatus for simultaneously monitoring the pressure and volume of liquid in the balloon catheter as the balloon is being dilated, such as in performing...
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4778784 |
Cyclic peptide and method of use for inducing an immunological response to hepatitis B virus
A composition for eliciting production of antibody to hepatitis B surface antigen and method of neutralizing the infectivity of hepatitis type B virus. A cyclic polypeptide is prepared having a...
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4753884 |
Pseudorabies virus mutants, vaccines containing same, methods for the production of same and methods for the use of same
The present invention relates to pseudorabies virus mutants containing deletion and/or insertion mutations in a major viral glycoprotein gene, such that no antigenic polypeptides encoded by the...
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4731076 |
Piezoelectric fluid pumping system for use in the human body
A totally or partially implantable fluid delivery system actuated by a valveless piezoelectric drive system. The drive system may actuate an artificial heart by a hydraulic bladder or directly...
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4712554 |
Electronic system to distinguish between sinus and nonsinus atrial depolarizations which do not stimulate ventricular depolarizations in response to nonsinus atrial depolarizations
An electronic system for maintaining atrio-ventricular synchrony that distinguishes between sinus and nonsinus atrial depolarizations and that stimulates ventricular contraction only when the...
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4711850 |
Pseudorabies virus mutants, vaccines containing same, methods for the production of same and methods for the use of same
The present invention relates to pseudorabies virus mutants containing deletion and/or insertion mutations in a major viral glycoprotein gene, such that no antigenic polypeptides encoded by the...
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4703011 |
Thymidine kinase deletion mutants of bovine herpesvirus-1
Bovine herpesvirus type 1 (infectious bovine rhinotracheitis virus) mutants which fail to produce any functional thymidine kinase as a result of a deletion in the thymidine kinase gene. The...
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4701407 |
Diagnosis of Alzheimer disease
The present invention is based on the discovery that amyotrophic lateral sclerosis (ALS), Parkinson disease and Alzheimer disease are due to lack of a disorder-specific neurotrophic hormone....
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4699875 |
Diagnosis of amyotrophic lateral sclerosis by neurotrophic factors
The present invention is based on the discovery that amyotrophic lateral sclerosis (ALS), Parkinson disease and Alzheimer disease are due to lack of a disorder-specific neurotrophic hormone....
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4657930 |
Mitotic inhibitors preventing posterior lens capsule opacification
Disclosed are mitotic inhibitors effective for and methods of preventing posterior lens capsule opacification after extracapsular extraction. The mitotic inhibitors comprise osmotically balanced...
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4651738 |
Method and device for performing transluminal angioplasty
A novel method and device for performing percutaneous transluminal angioplasty to treat occlusive artery disease is disclosed. The method involves simultaneous measurement and display of the fluid...
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4649911 |
Small particle aerosol generator for treatment of respiratory disease including the lungs
Disclosed is a small particle aerosol or nebulizer apparatus effective for providing small particles of aerosol containing drug; that is, particles having a maximum diameter of 10 microns but...
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4640130 |
Method and apparatus for acoustically measuring the volume of an object
A non-invasive method and apparatus for measuring the volume of an object such as an infant using the principle of the Helmholtz resonator. A container having a cavity therein containing gas and...
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4609548 |
Vaccines for pseudorabies disease and methods for use of same
Temperature-resistant pseudorabies viruses which fail to produce any functional TK as a result of mutagen-induced mutation and temperature-resistant pseudorabies viruses which fail to produce any...
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4573883 |
Disposable blood pump
A hemocompatible flexible diaphragm and flexible wall pumping chamber positioned in a rigid body and actuated by alternating positive and negative fluid pulses. An inlet valve and an outlet valve...
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4569840 |
Thymidine kinase-negative temperature resistant bovine herpesvirus-1 mutant as a vaccine against infectious bovine rhinotracheitis
Described are thymidine kinase negative temperature resistant mutants of bovine herpesvirus effective in inducing resistance to infectious bovine rhinotracheitis, methods for their production,...
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4522194 |
Method and an apparatus for intra-aortic balloon monitoring and leak detection
A method of and an apparatus for intra-aortic balloon monitoring and leak detection in which the balloon is inserted into the aorta of a body and the balloon is inflated and deflated with gas by a...
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4515794 |
Mitotic inhibitors preventing posterior lens capsule opacification
Disclosed are mitotic inhibitors effective for and methods of preventing posterior lens capsule opacification after extracapsular extraction. The mitotic inhibitors comprise osmotically balanced...
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4514497 |
Modified live pseudorabies viruses
Temperature-resistant pseudorabies viruses which fail to produce any functional TK as a result of mutagen-induced mutation and temperature-resistant pseudorabies viruses which fail to produce any...
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4448890 |
Detection of human cancer cells with antibodies to human cancer nucleolar antigens
Specific common nucleolar antigens are found in a broad range of human malignant tumor specimens and have been isolated, extracted and purified. Antibodies and antisera specific to these nucleolar...
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4432751 |
Monoclonal antibodies against lens epithelial cells and preventing proliferation of remnant lens epithelial cells after extracapsular extraction
Disclosed are monoclonal antibodies against lens epithelial cells and methods of producing them. Continuous cell lines for producing monoclonal antibodies to lens epithelial cells are disclosed....
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4419369 |
Protein mineral dietary module
Disclosed is an improved dietary protein mineral module composed of a high quality protein, such as calcium-sodium caseinate, and electrolytes (minerals) combined in a fixed ratio so that when the...
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4365199 |
Nuclear magnetic resonance sample tube insert
An insert for insertion into a circularly cross-sectioned sample tube for use in nuclear magnetic resonance spectrometry for reducing temperature variations in the sample and dispersing heat...
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4336337 |
Detection of bacteria
A test substrate, including a semi-permeable membrane which retains bacteria on the membrane and which has a net positive surface charge to permit coloring of bacteria thereon with a cationic dye,...
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4311794 |
Determination of bacterial growth activity and antibiotic sensitivity by catalase measurement
A catalase method and apparatus are disclosed for direct measurement of bacterial growth activity in the presence and absence of antibiotics, and for the determination of antibiotic sensitivity...
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4277250 |
Methods for detecting and quantifying occult blood
A method for detecting occult blood in aqueous samples of human specimens, particularly aqueous suspensions of fecal matter is disclosed. The method comprises acidifying an aqueous test sample,...
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4263405 |
Apparatus for measuring the approximate number of aerobic bacteria in water and other fluids
A simple and functional apparatus is disclosed for use in the home, field and other places in which water or other fluids can be evaluated for the presence of bacteria. Also disclosed is a...
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4255022 |
Method of and apparatus for examination of visual fields
A microprocessor based instrument designed to retrofit into existing perimeters utilizing the mechanics and stimulus control aspects of the existing perimeter. The device includes an array board...
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4239351 |
Apparatus for generating and displaying visual acuity targets
First and second electro-optical display devices for displaying visual acuity targets, one of which is adapted to be viewed by a patient and the other of which is adapted to be viewed by an...
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4159637 |
Hydraulic test tool and method
A test tool and a method of testing is disclosed for testing for leaks in apparatus having a bore and a landing surface, such as blowout preventers, wellheads, casing hangers, and the like. The...
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4095859 |
Portable eye examination system cart
A portable eye examination system cart is provided with an instrument console which conveniently supports eye examination devices, an electric power system effective to provide electrical power to...
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4043911 |
Sterilization of holding tanks and toilet bowls by quaternary compounds
Wastewaters heavily laden with organic compounds and containing viruses and other microbiological flora are sterilized and maintained sterile for prolonged periods of time by the addition of a...
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4043346 |
Catheter
A catheter is disclosed which is simple to use, avoids the problems with prior catheters, which is fail-safe and fool-proof and one by which the patient cannot injure himself. The catheter...
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4019813 |
Optical apparatus for obtaining measurements of portions of the eye
An optical apparatus for obtaining one or more measurements of portions of an eye having means for providing a narrow beam of light through the eye, a lens system that collects light that is...
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4015590 |
Balloon activated blood pump
A pneumatically driven balloon activated blood pump for connection either in parallel with or to one side of the heart for temporary mechanical support of an inadequately functioning heart. A...
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3974825 |
Remote electrical monitoring of gas activated blood pumps
An electrical capacitance measurement system for monitoring at a distance the instantaneous blood volume within the body of an air or gas activated blood pump. Electrical capacitance changes within...
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3957036 |
Method and apparatus for recording activity in intact nerves
A method and apparatus is provided which will attenuate bioelectric interference when measuring the activity in an intact nerve. An electrode probe is provided having first and second electrodes...
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3941696 |
Sterilization of holding tanks and toilet bowls by quaternary compounds
Wastewaters heavily laden with organic compounds and containing viruses and other microbiological flora are sterilized and maintained sterile for prolonged periods of time by the addition of a...
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3905688 |
Apparatus for determining the acuity of a human
An acuity meter for presenting visual acuity targets to the eye of a human subject being tested in order to determine accurately and conveniently the acuity capability of his visual system. The...
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