Matches 1 - 50 out of 86 1 2 >


Match Document Document Title Score
WO/2017/199073A1 EFFERVESCENT DEFERIPRONE TABELT  
An oral pharmaceutical formulation for effervescent tablet of deferiprone is reported comprising of deferiprone and a taste-masking composition consisting of an effective amount of sweetener and...
1000
WO/1997/003971A1 PROCESS FOR THE MANUFACTURE OF BIS-TRIAZOLE COMPOUNDS AND INTERMEDIATES USEFUL IN THE MANUFACTURE THEREOF HAVING ANTIFUNGAL ACTIVITY  
A process to prepare a compound of formula (I) wherein Y and Z can be identical or different and represent a halogene. The bis-triazole compounds of formula (I) and intermediates have antifungal...
807
WO/1994/005628A1 SYNTHESIS OF 2-SUBSTITUTED QUINAZOLINE COMPOUNDS (SUCH AS TERAZOSIN) AND MEOBENTINE AND BETHANIDINE AND INTERMEDIATES THEREFOR  
Novel methods for the synthesis of substituted ureas and guanidines including Terazosin, Prazosin, Doxazosin, Tiodazosin, Trimazosin, Quinasin and Bunazosin (exemplary of 2-amino substituted...
807
WO/1995/007895A1 METHODS FOR THE MANUFACTURE OF FLUCONAZOLE AND FORMS THEREOF, INTERMEDIATES USEFUL IN THE MANUFACTURE THEREOF, AND COMBINATIONS COMPRISING FLUCONAZOLE  
A process for making fluconazole comprising the steps shown above.
788
WO/1991/004244A1 NADOLOL  
A process for making 5-{d-3-(tert-butylamino)-2-hydroxypropoxy}-1,2,3,4-tetrahydr o-1-cis-2,3 naphthalenediol of formula (I), by reacting formula (II) in an essentially water free environment with...
698
WO/2016/110761A1 PROCESS FOR PRODUCING 1-β-D-ARABINOFURANOSYLCYTOSINE AND 2,2'-O-CYCLOCYTIDINE  
An efficient and simple process is provided for producing 1-β-D-arabinofuranosylcytosine or cytarabine wherein cytidine hydrochloride is converted to the corresponding 2,2'-...
686
5817875 Methods for the manufacture of terbinafine  
Process for the manufacture of naphthylmethylamine derivatives and among them terbinafine as potential antimycotic agents.
672
6046332 Methods for the manufacture of cetirizine  
The present invention relates to a process for the preparation of a [2-[4-[4-(chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]ac etic acid derivative of formula I: and, in particular, for the...
637
6063933 Process for the manufacture of bis-triazole compounds and intermediates useful in the manufacture thereof having antifungal activity  
PCT No. PCT/CA96/00483 Sec. 371 Date Feb. 24, 1998 Sec. 102(e) Date Feb. 24, 1998 PCT Filed Jul. 17, 1996 PCT Pub. No. WO97/03971 PCT Pub. Date Feb. 6, 1997The present invention relates to a...
629
WO/2018/138569A1 NEW DESIGN FOR DOUBLE CONE BLENDER DRYER USED TO PRODUCE PHARMACEUTICAL READY-TO-PRESS GRANULES  
The present invention relates to an innovative apparatus and its application in the production of granules used in various industries. The said apparatus consists of a double cone blender dryer,...
629
WO/2016/097989A1 PROCESS FOR THE PREPARATION OF GEMCITABINE HYDROCHLORIDE  
The present invention relates to an improved as well as an industrially viable process for the preparation of 2'-deoxy-2',2'-difluorocytidine and its pharmaceutical acceptable acid salts thereof...
629
WO/1999/065892A1 PROCESS TO MANUFACTURE SIMVASTATIN AND INTERMEDIATES  
A process is disclosed for the preparation of simvastatin which enables highly regio selective C-methylation of the 2'-position group of lovastatin without requiring protection/deprotection of...
629
WO/2018/042287A1 PEGYLATED RESOLVING AGENTS FOR IMPROVED RESOLUTION OF RACEMIC MIXTURE  
The present invention is related to a product for the resolution of racemic mixtures in which various separation processes of a salt composed of a PEGylated resolving agent and an enantiomer in a...
629
WO/2016/098015A1 NEW EFFICIENT METHODS FOR THE SYNTHESIS OF TAXANE DERIVATIVES SUCH AS DOCETAXEL AND THEIR STRUCTURAL ANALOGOUS, AND A METHOD FOR THE PREPARATION THEREOF  
The present invention relates to a novel process for the preparation of taxanes such as Docetaxel, a very important anticancer drug. Docetaxel 1 is a clinically well-established anti -mitotic...
629
WO/1991/013900A1 PROCESS FOR PRODUCING 2,2'-O-CYCLONUCLEOSIDES, NUCLEOSIDES, AND ANALOGS THEREOF  
A novel process is provided for producing a nucleoside, such as cytarabine, or a nucleoside analogue, comprising the step of reacting 2,2'-O-cyclonucleoside or an analogue thereof with an amine....
582
WO/1998/002425A1 METHODS FOR THE MANUFACTURE OF CETIRIZINE  
A process for the manufacture of [2-[4-[4-(chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]ac etic acid derivatives of formula (I) is provided.
582
WO/2001/090095A1 THIADIAZOLE COMPOUNDS USEFUL AS INHIBITORS OF CYSTEINE ACTIVITY DEPENDENT ENZYMES  
Novel 1,2,4-thiadiazole compounds are provided, which are effective as inhibitors of cysteine activity-dependent enzymes and in particular of cysteine proteases. The compounds are useful in...
503
EP0840730A1 PROCESS FOR THE MANUFACTURE OF BIS-TRIAZOLE COMPOUNDS AND INTERMEDIATES USEFUL IN THE MANUFACTURE THEREOF HAVING ANTIFUNGAL ACTIVITY  
Abstract not available for EP0840730 Abstract of corresponding document: US6063933 PCT No. PCT/CA96/00483 Sec. 371 Date Feb. 24, 1998 Sec. 102(e) Date Feb. 24, 1998 PCT Filed Jul. 17, 1996 PCT...
470
DE69015151D1 Verfahren zur Herstellung von Nadolol.   470
DE69902212D1 Azithromycinmonohydrat-Isopropanol-Clathrate und Methoden zu deren Herstellung   470
DE69902212T2 Azithromycinmonohydrat-Isopropanol-Clathrate und Methoden zu deren Herstellung   470
DE69902788T2 VERFAHREN ZU HERSTELLUNG VON SIMVASTATIN UND ZWISCHENPRODUKTEN   470
DE69015151T2 Verfahren zur Herstellung von Nadolol.   470
DE69902788D1 VERFAHREN ZU HERSTELLUNG VON SIMVASTATIN UND ZWISCHENPRODUKTEN   470
6093738 Proton pump inhibitors  
Novel thiadiazole compounds are provided, which are effective as proton pumps inhibitors, useful in treating peptic ulcers by inhibition of the proton pump enzyme H+ /K+ -ATPase. The compounds are...
465
WO/1991/013901A1 3'-O-TOSYLCYTIDINE AND CYTOSINE COMPOUNDS, AND PROCESS FOR PRODUCTION THEREOF  
Compounds of formula (IV), wherein R?6� is selected from the group comprising a trifluoromethyl group, a C�1?-C�6? alkyl group and a C�6?-C�9? aryl group, and R?1� is selected from the group...
465
WO/2004/083227A1 ISOPROPANOLATE OF AZITHROMYCIN AND METHOD OF MANUFACTURING  
Azithromycin isopropanolate of the empirical formula azithromycin: [H20]x: [isopropanol]y is obtained from the crystallization of azithromycin in isopropanol and water. The x and y values is...
465
6245903 Azithromycin monohydrate isopropanol clathrate and methods for the manufacture thereof  
A novel form of azithromycin and processes for preparation of pure azithromycin monohydrate isopropanol clathrate (3 molecules of isopropanol for every 10 molecules of azithromycin monohydrate)...
411
5399682 Process for preparing 2,3'-O-cyclocytidine  
A process for preparing 2,3'-O-cyclocytidine wherein 3'-deoxy-3'-organosulfonyl cytidine is refluxed in the absence of base. 2,3'-cyclocytidine is an intermediate in the preparation of...
411
EP0984020A3 Azithromycin monohydrate isopropanol clathrate and methods for the manufacture thereof.  
Abstract of EP0984020 A novel form of azithromycin and processes for preparation of pure azithromycin monohydrate isopropanol clathrate (3 molecules of isopropanol for every 10 molecules of...
403
EP0883606A1 PROCESS FOR SCAVENGING THIOLS  
Abstract not available for EP0883606 Abstract of corresponding document: WO9731893 Thiols are trapped, and converted to disulfide compounds, by a process of reacting them with compounds containing...
403
EP1058690A1 THIADIAZOLE COMPOUNDS USEFUL AS INHIBITORS OF CYSTEINE ACTIVITY DEPENDENT ENZYMES   403
EP0445250A1 Process for preparing nadolol.  
Abstract not available for EP0445250 Abstract of corresponding document: US5319141 PCT No. PCT/CA90/00316 Sec. 371 Date May 20, 1991 Sec. 102(e) Date May 20, 1991 PCT Filed Sep. 25, 1990 PCT Pub....
403
EP0521923A1 PROCESS FOR PRODUCING NUCLEOSIDES, AND ANALOGS THEROF.  
Abstract not available for EP0521923 Abstract of corresponding document: WO9113900 A novel process is provided for producing a nucleoside, such as cytarabine, or a nucleoside analogue, comprising...
403
EP0656885A1 SYNTHESIS OF 2-SUBSTITUTED QUINAZOLINE COMPOUNDS (SUCH AS TERAZOSIN) AND MEOBENTINE AND BETHANIDINE AND INTERMEDIATES THEREFOR.  
Abstract not available for EP0656885 Abstract of corresponding document: WO9405628 Novel methods for the synthesis of substituted ureas and guanidines including Terazosin, Prazosin, Doxazosin,...
403
EP0523080A1 3'-O-TOSYLCYTIDINE AND CYTOSINE COMPOUNDS, AND PROCESS FOR PRODUCTION THEREOF.  
Abstract not available for EP0523080 Abstract of corresponding document: US5399682 PCT No. PCT/CA91/00078 Sec. 371 Date Oct. 5, 1992 Sec. 102(e) Date Oct. 5, 1992 PCT Filed Mar. 13, 1991 PCT Pub....
403
EP1087958A1 PROCESS TO MANUFACTURE SIMVASTATIN AND INTERMEDIATES   403
DE69712608D1 PROTONENPUMPINHIBITOREN   403
DE69108014T2 VERFAHREN ZUR HERSTELLUNG VON NUCLEOSIDEN UND IHRE ANALOGEN.   403
DE69111438D1 2,3'-O-CYCLOCYTIDINE UND VERFAHREN ZU DEREN HERSTELLUNG.   403
DE69712608T2 PROTONENPUMPINHIBITOREN   403
DE69108014D1 VERFAHREN ZUR HERSTELLUNG VON NUCLEOSIDEN UND IHRE ANALOGEN.   403
DE69111438T2 2,3'-O-CYCLOCYTIDINE UND VERFAHREN ZU DEREN HERSTELLUNG.   403
5610292 Process for producing 2,2'-o-cyclonucleosides nucleosides, and analogs thereof  
A novel process is provided for producing a nucleoside, such as cytarabine, or a nucleoside analogue, comprising the step of reacting 2,2'-O-cyclonucleoside or an analogue thereof with an amine....
376
WO/1995/021183A1 HALOGENATED DERIVATIVES OF 2,3'-O-CYCLOCYTIDINE COMPOUNDS AND PROCESS FOR PRODUCTION THEREOF  
In one of its aspects, the present invention provides novel compounds of formula (I) wherein: X is a halide; Y is selected from the group consisting essentially of halide, sulfate, acetate, tosyl,...
356
6162791 Thiadiazole compounds useful as inhibitors of cysteine activity dependent enzymes  
Novel 1,2,4-thiadiazole compounds are provided, which are effective as inhibitors of cysteine activity-dependent enzymes and in particular of cysteine proteases. The compounds are useful in...
336
6060472 Thiadiazole compounds useful as inhibitors of H+ /K+ atpase  
Novel 3,5-disubstituted 1,2,4-thiadiazole compounds are provided, which are effective in treating peptic ulcers by the inhibition of H+ /K+ -ATPase. The compounds of the present invention are...
336
5847118 Methods for the manufacture of amorphous cefuroxime axetil  
A process for preparing pure amorphous cefuroxime axetil comprising the steps of dissolving crystalline cefuroxime axetil in a highly polar organic solvent and adding the resulting solution to...
336
5536824 Organosulfonyl salts of 2,3'-O-cyclocytidine  
Compounds of Formula IV: ##STR1## are described. In the compounds of Formula IV, R6 is selected from a trifluoromethyl group, a C1 -C6 alkyl group and a C6 -C9 aryl group, and R1 is selected from...
336
5319141 Process of making nadolol  
A process for making 5-(d-3-(tert-butylamino)-2-hydroxypropoxy)-1,2,3,4-tetrahydr o-1-cis-2,3 naphthalenediol of the formula ##STR1## by reacting ##STR2## in an essentially water free environment...
336


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