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7642289 |
Drugs for chronic pain
The present invention relates to nitrooxyderivatives or salts thereof having the following general formula (I):
R—NR 1c —(K) k0...
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7629368 |
Nitroderivatives as drugs for diseases having an inflammatory basis
Use for the treatment of diseases having an inflammatory basis of compounds or salts thereof, Having the following general formula (I): A—X 1 —L—(W) p —NO 2 wherein A contains the radical...
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7629345 |
Prostaglandin derivatives
Prostaglandin nitroderivatives having improved pharmacological activity and enhanced tolerability are described. They can be employed for the treatment of glaucoma and ocular hypertension.
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US20090264394 |
NITROOXY DERIVATIVES OF GLUCOCORTICOIDS
The invention relates to new steroids nitrooxyderivatives, to topical pharmaceutical formulations thereof, and their use for treating skin or mucosal membrane diseases or disorders. These new...
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US20090264393 |
NITROOXY DERIVATIVES OF GLUCOCORTICOIDS
The invention relates to new steroids nitrooxyderivatives, to topical pharmaceutical formulations thereof, and their use for treating skin or mucosal membrane diseases or disorders. These new...
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US20090263472 |
ENDOTHELIN RECEPTOR ANTAGONIST DERIVATIVES
Endothelin receptor antagonist nitroderivatives of general formula (I):
having an improved pharmacological activity compared with their parent compounds. They can be employed for treating or...
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7605151 |
Nitrate esters of corticoid compounds and pharmaceutical applications thereof
Compounds of the formula
and use of the compounds as medicaments.
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US20090258849 |
NITROOXY DERIVATIVES OF GLUCOCORTICOIDS
The invention relates to new steroids nitrooxyderivatives, to topical pharmaceutical formulations thereof, and their use for treating skin or mucosal membrane diseases or disorders. These new...
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7595313 |
Nitric oxide donating diuretic compounds, compositions and methods of use
The invention describes novel compositions and kits comprising at least one nitric oxide enhancing diuretic compound, or pharmaceutically acceptable salts thereof, and, optionally, at least one...
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US20090239832 |
DRUGS FOR CHRONIC PAIN
The present invention relates to nitrooxyderivatives or salts thereof having the following general formula (I):
R—NR 1c —(K) k0...
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7589124 |
Nitrosated and/or nitrosylated cyclooxygenase-2 selective inhibitors, compositions and methods of use
The invention provides novel nitrosated and/or nitrosylated cyclooxygenase 2 (COX-2) selective inhibitors and novel compositions and kits comprising at least one nitrosated and/or nitrosylated...
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US20090221543 |
NEW CORTICOSTEROIDS
Nitrooxy derivatives of steroidal compounds of general formula
B—X 1 —NO 2 (I)
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7563909 |
Statin derivatives
Statin nitroderivatives having improved pharmacological activity and enhanced tolerability are described. They can be employed for treating and/or preventing several diseases, in particular...
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US20090170941 |
Pharmaceutical Compounds
Compounds or their salts of general formula (I): A-B—N(O) s wherein: s is an integer equal to 1 or 2; A=R-T 1 -, wherein R is the drug radical and T 1 =(CO) t or (X) t′ , wherein X=O, S, NR...
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US20090170934 |
MANUFACTURING PROCESS FOR NO-DONATING COMPOUNDS SUCH AS NO-DONATING DICLOFENAC
The present invention relates to a new process for the preparation of NO-donating compounds using a sulfonated intermediate. The invention relates to new intermediates prepared therein suitable for...
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7544711 |
Use of nitroderivatives in urinary incontinence
The present invention relates to the use of the following compounds, their compositions, and their salts for the preparation of medicaments for the treatment of urinary incontinence and other...
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7524836 |
Nitrooxyderivative steroidal compounds
Steroidal compounds or their salts having general formulas (I) and (II) wherein: s is an integer equal to 1 or 2, preferably s=2; b0=0 or 1; A=R—, wherein R is the steroidal drug radical, C and C...
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US20090075952 |
NITRODERVIATIVES AS DRUGS FOR DISEASES HAVING AN INFLAMMATORY BASIS
Use for the treatment of diseases having an inflammatory basis of compounds or salts thereof, having the following general formula (I): A-X 1 -L-(W) p -NO 2 wherein A contains the radical of a...
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US20090030076 |
PROSTAGLANDIN DERIVATIVES
Prostaglandin nitroderivatives having improved pharmacological activity and enhanced tolerability are described. They can be employed for the treatment of glaucoma and ocular hypertension.
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7465803 |
Nitroderivatives as drugs for diseases having an inflammatory basis
Use for the treatment of diseases having an inflammatory basis of compounds or salts thereof, having the following general formula (I): A-X 1 -L-(W) p —NO 2 wherein A contains the radical of a...
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7462716 |
Statin derivatives
Stating nitro derivatives having improved pharmacological activity and enhanced tolerability are described. They can be employed for treating and/or preventing several diseases, in particular...
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7449469 |
Prostaglandin derivatives
Prostaglandin nitroderivatives having improved pharmacological activity and enhanced tolerability are described. They can be employed for the treatment of glaucoma and ocular hypertension.
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US20080269323 |
USE OF 4-(NITROOXY)-BUTYL-(S)-2-(6-METHOXY-2-NAPHTHYL)-PROPANOATE FOR TREATING PAIN AND INFLAMMATION
The present invention relates to the use of 4-(Nitrooxy)-butyl-(S)-2-(6-methoxy-2-naphthyl)-propanoate (naproxcinod) for treating pain and inflammation, in particular musculo-skeletal disorders, in...
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7442826 |
Process for the preparation of nitrooxyderivatives of paracetamol
The present invention relates to a new process for the preparation of a compound of the following formula (I):
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US20080234242 |
NITRATE ESTERS OF CORTICOID COMPOUNDS AND PHARMACEUTICAL APPLICATIONS THEREOF
Compounds of the formula
and use of the compounds as medicaments.
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US20080194651 |
NITRODERIVATIVES AS DRUGS FOR DISEASES HAVING AN INFLAMMATORY BASIS
Use for the treatment of diseases having an inflammatory basis of compounds or salts thereof, Having the following general formula (I): A-X 1 -L-(W) p —NO 2 wherein A contains the radical of a...
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7402600 |
Nitroderivatives of cardiovascular agents
Compounds or their salts having general formulas (I) and (II) wherein: s=is an integer equal to 1 or 2, preferably s=2; b0=0 or 1; A is the radical of a drug and is such as to meet the...
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7399878 |
Pharmaceutical compounds
Compounds or their salts of general formula (I): A-B-N(O) s wherein: s is an integer equal to 1 or 2; A=R-T 1 -, wherein R is the drug radical and T 1 =(CO) t or (X) t′ , wherein X=O, S, NR 1c...
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7378437 |
Drugs for diabetes
Use for the diabetes treatment of compounds or salts thereof, having the following general formula (I): A-(B) b0 —(C) c0 —NO 2 wherein A contains the radical of a drug having an...
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7378412 |
Pharmaceutical compounds
Compounds or their salts having general formula:
A-B—C—NO 2
wherein: A...
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US20080113950 |
Drugs for chronic pains
Nitro-oxyderivative compounds or salts thereof having the following general formula (I): A-(B)b0-(C)o0-N02 wherein: c0 is an integer and is 0 or 1, b0 is an integer and is 0 or 1, A=R-TI-, wherein...
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7368442 |
Nitrate esters of corticoid compounds and pharmaceutical applications thereof
Compounds of the formula
and use of the compounds as medicaments.
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US20080096908 |
Statin derivatives
Statin nitroderivatives having improved pharmacological activity and enhanced tolerability are described. They can be employed for treating and/or preventing several diseases, in particular...
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US20080090857 |
Statin derivatives
Statin nitroderivatives having improved pharmacological activity and enhanced tolerability are described. They can be employed for treating and/or preventing several diseases, in particular...
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US20080058392 |
PROSTAGLANDIN DERIVATIVES
Prostaglandin nitroderivatives having improved pharmacological activity and enhanced tolerability are described. They can be employed for the treatment of glaucoma and ocular hypertension.
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7297808 |
Statin derivatives
Statin nitroderivatives having improved pharmacological activity and enhanced tolerability are described. They can be employed for treating and/or preventing several diseases, in particular...
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7273946 |
Prostaglandin derivatives
Prostaglandin nitroderivatives having improved pharmacological activity and enhanced tolerability are described. They can be employed for the treatment of glaucoma and ocular hypertension.
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US20070197499 |
Pharmaceutical compounds
Compounds or their salts of general formula (I): A-B—N(O) s wherein: s is an integer equal to 1 or 2; A=R-T 1 -, wherein R is the drug radical and T 1 =(CO) t or (X) t′ , wherein X═O, S, NR...
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US20070161612 |
Nitrate esters of corticoid compounds and pharmaceutical applications thereof
Compounds of the formula
and use of the compounds as medicaments.
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US20070161576 |
Drugs for chronic pains
Nitro-oxyderivative compounds or salts thereof having the following general formula (I): A-(B) b0 —(C) c0 —NO 2 wherein: c0 is an integer and is 0 or 1, b0 is an integer and is 0 or 1, A=R-T 1...
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7238829 |
Process for the preparation of naproxene nitroxyalkylesters
A process for obtaining nitroxyalklesters of the 2(S)(6-methoxy-2-naphthyl)-propanoic acid having an enantiomeric excess higher than or equal to 95%, preferably higher than or equal to 98%,...
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US20070142342 |
Pharmaceutical compounds
Steroidal compounds or their salts having general formulas (I) and (II) wherein: s is an integer equal to 1 or 2, preferably s-2: bO 0 or 1; A═R—, wherein R is the steroidal drug radical, C and...
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7217733 |
ACE inhibitor derivatives
ACE inhibitor nitroderivatives of formula (I):
A—(X 1 —ONO 2 ) s (I)
...
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7205288 |
Nitrate esters of corticoid compounds and pharmaceutical applications thereof
Compounds of the formula
and use of the compounds as medicaments.
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7199258 |
Process for preparing nitrooxyderivatives of naproxen
The present invention refers to a process for preparing a compound of general formula (A), as reported in the description, wherein R is a radical of naproxen or bromonaproxen and R 1 –R 12 are...
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7199141 |
Drugs for chronic pains
Nitro-oxyderivative compounds or salts thereof having the following general formula (I): A—(B) b0 —(C) c0 —NO 2 wherein: c0 is an integer and is 0 or 1, b0 is an integer and is 0 or 1,...
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US20070072942 |
Statin derivatives
Statin nitroderivatives having improved pharmacological activity and enhanced tolerability are described. They can be employed for treating and/or preventing several diseases, in particular...
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7196075 |
Nitrate esters of corticoid compounds and pharmaceutical applications thereof
Compounds of the formula
and use of the compounds as medicaments.
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7186753 |
Pharmaceutical compounds
Compounds or their salts of general formula (I): A—B—N(O) s wherein: s is an integer equal to 1 or 2; A=R—T 1 —, wherein R is the drug radical and T 1 =(CO) t or (X) t′ , wherein X=O,...
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7186708 |
Steroidal compounds
Steroidal compounds or their salts having general formula:
A—B—C—NO 2
...
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