Matches 1 - 28 out of 28


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9708344 Inhibitors of UDP-galactopyranose mutase  
Compounds and salts thereof which inhibit microbial growth or attenuate the virulence of pathogenic microorganisms and which inhibit UDP-galactopyranose mutase (UGM). Compounds of the invention...
WO/2017/007695A1 MU OPIOID RECEPTOR MODULATORS  
Described herein, inter alia, are compositions and methods for modulating mu opioid receptor activity.
9371337 β-lactamase inhibitors  
Disclosed herein inter alia are Boron containing compounds and methods for treating infections related to antibiotic resistant microorganisms.
US20150344501 INHIBITORS OF UDP-GALACTOPYRANOSE MUTASE  
Compounds and salts thereof which inhibit microbial growth or attenuate the virulence of pathogenic microorganisms and which inhibit UDP-galactopyranose mutase (UGM). Compounds of the invention...
US20140315861 BETA-LACTAMASE INHIBITORS  
Disclosed herein inter alia are Boron containing compounds and methods for treating infections related to antibiotic resistant microorganisms.
WO/2013/056163A1 BETA-LACTAMASE INHIBITORS  
Disclosed herein inter alia are Boron containing compounds and methods for treating infections related to antibiotic resistant microorganisms.
7928129 Nanomolar β-lactamase inhibitors  
New carboxyphenyl-glycylboronic acid transition-state analog inhibitors, representative of a class of compounds effective against class C β-lactamase AmpC. The new compounds improve inhibition by...
US20090318711 Non-Covalent Inhibitors of AmpC ß-Lactamase  
β-lactamases are the most widespread resistance mechanism to β-lactam antibiotics, such as penicillins and cephalosporins. In response to these enzymes, inhibitors have been introduced....
7541381 Non-covalent inhibitors of AmpC β-lactamase  
β-lactamases are the most widespread resistance mechanism to β-lactam antibiotics, such as penicillins and cephalosporins. In response to these enzymes, inhibitors have been introduced....
7271186 Nanomolar β-lactamase inhibitors  
New carboxyphenyl-glycylboronic acid transition-state analog inhibitors, representative of a class of compounds effective against class C β-lactamase AmpC. The new compounds improve inhibition by...
WO/2007/053189A3 COMPOSITIONS AND METHODS FOR ALTERING IMMUNE FUNCTION  
The present invention relates to molecules that stabilize and/or enhance CD 154 activity, compositions comprising these molecules, methods for using these molecules and compositions (e.g.,...
WO/2007/053189A2 COMPOSITIONS AND METHODS FOR ALTERING IMMUNE FUNCTION  
The present invention relates to molecules that stabilize and/or enhance CD 154 activity, compositions comprising these molecules, methods for using these molecules and compositions (e.g.,...
US20050245498 Sterically-awkward beta-lactamase inhibitors  
Sterically-awkward 6-β-substituted P-lactam compounds as inhibitors of β-lactamase activity, such compounds as can be used in conjunction with one or more β-lactam antibiotics in a system for...
6887658 Methods of identifying non-specific inhibitors of biomolecules  
The present invention provides methods of identifying compounds that non-specifically inhibit biological reactions. The present invention further includes kits that facilitate this identification....
WO/2004/037163A3 STERICALLY-AWKWARD beta-LACTAMASE INHIBITORS  
6(7)-beta-substituted beta-lactam compounds as inhibitors of beta-lactamase activity.
US20040234942 METHODS OF IDENTIFYING NON-SPECIFIC INHIBITORS OF BIOMOLECULES  
The present invention provides methods of identifying compounds that non-specifically inhibit biological reactions. The present invention further includes kits that facilitate this identification....
WO/2004/037163A2 STERICALLY-AWKWARD β-LACTAMASE INHIBITORS  
6(7)-β-substituted β-lactam compounds as inhibitors of β-lactamase activity.
US20030236243 Sterically-awkward beta-lactamase inhibitors  
6(7)-β-substituted β-lactam compounds as inhibitors of β-lactamase activity.
US20030232830 Non-covalent inhibitors of AmpC beta-lactamase  
β-lactamases are the most widespread resistance mechanism to β-lactam antibiotics, such as penicillins and cephalosporins. In response to these enzymes, inhibitors have been introduced....
WO/2003/070682A1 NON-COVALENT INHIBITORS OF AmpC ß-LACTAMASE  
ß-lactamases are the most widespread resistance mechanism to ß-lactam antibiotics, such as penicillins and cephalosporins. In response to these enzymes, inhibitors have been introduced....
6448238 Inhibitors of β-lactamases and uses therefor  
The invention provides novel non-β-lactam inhibitors of β-lactamases. In particular, the invention provides such inhibitors which are boronic acids of formula (1) which is set forth in the...
WO/2002/022137A1 $g(b)-LACTAM ANALOGS AND USES THEREFOR  
The invention provides a method of treating a $g(b)-lactam-antibiotic-resistant bacterial infection with a combination of a $g(b)-lactamanalog. The invention also provides a method of inhibiting a...
6184363 Inhibitors of β-lactamases and uses therefor  
The invention provides novel non-β-lactam inhibitors of β-lactamases. In particular, the invention provides such inhibitors which are boronic acids of formula (1) which is set forth in the...
EP1009415A4 INHIBITORS OF $g(b)-LACTAMASES AND USES THEREFOR  
WO/2000/035905A1 INHIBITORS OF $g(b)-LACTAMASES AND USES THEREFOR  
The invention provides novel non-$g(b)-lactam inhibitors of $g(b)-lactamases. In particular, the invention provides such inhibitors which are boronic acids of formula (1) which is set forth in the...
WO/2000/035904A1 INHIBITORS OF $g(b)-LACTAMASES AND USES THEREFOR  
The invention provides novel non-$g(b)-lactam inhibitors of $g(b)-lactamases. In particular, the invention provides such inhibitors which are boronic acids of formula (1) which is set forth in the...
EP1009415A1 INHIBITORS OF $g(b)-LACTAMASES AND USES THEREFOR  
WO/1998/056392A1 INHIBITORS OF $g(b)-LACTAMASES AND USES THEREFOR  
The invention provides novel non-$g(b)-lactam inhibitors of $g(b)-lactamases. In particular, the invention provides such inhibitors which are boronic acids of formula (1) which is set forth in the...


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