Matches 1 - 36 out of 36


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US20190076398 MU OPIOID RECEPTOR MODULATORS  
Described herein, inter alia, are compositions and methods for modulating mu opioid receptor activity.
WO/2019/036678A1 MU OPIOID RECEPTOR MODULATORS  
Described herein, inter alia, are compositions and methods for modulating mu opioid receptor activity.
US20190055208 MU OPIOID RECEPTOR MODULATORS  
Described herein, inter alia, are compositions and methods for modulating mu opioid receptor activity.
EP3319444A4 MU OPIOID RECEPTOR MODULATORS  
10118934 Inhibitors of UDP-galactopyranose mutase  
Compounds and salts thereof which inhibit microbial growth or attenuate the virulence of pathogenic microorganisms and which inhibit UDP-galactopyranose mutase (UGM). Compounds of the invention...
WO/2018/129393A1 MU OPIOID RECEPTOR MODULATORS  
Described herein, inter alia, are compositions and methods for modulating mu opioid receptor activity.
EP3319444A1 MU OPIOID RECEPTOR MODULATORS  
US20170283437 Inhibitors of UDP-Galactopyranose Mutase  
Compounds and salts thereof which inhibit microbial growth or attenuate the virulence of pathogenic microorganisms and which inhibit UDP-galactopyranose mutase (UGM). Compounds of the invention...
9708344 Inhibitors of UDP-galactopyranose mutase  
Compounds and salts thereof which inhibit microbial growth or attenuate the virulence of pathogenic microorganisms and which inhibit UDP-galactopyranose mutase (UGM). Compounds of the invention...
WO/2017/007695A1 MU OPIOID RECEPTOR MODULATORS  
Described herein, inter alia, are compositions and methods for modulating mu opioid receptor activity.
9371337 β-lactamase inhibitors  
Disclosed herein inter alia are Boron containing compounds and methods for treating infections related to antibiotic resistant microorganisms.
US20150344501 INHIBITORS OF UDP-GALACTOPYRANOSE MUTASE  
Compounds and salts thereof which inhibit microbial growth or attenuate the virulence of pathogenic microorganisms and which inhibit UDP-galactopyranose mutase (UGM). Compounds of the invention...
US20140315861 BETA-LACTAMASE INHIBITORS  
Disclosed herein inter alia are Boron containing compounds and methods for treating infections related to antibiotic resistant microorganisms.
WO/2013/056163A1 BETA-LACTAMASE INHIBITORS  
Disclosed herein inter alia are Boron containing compounds and methods for treating infections related to antibiotic resistant microorganisms.
7928129 Nanomolar β-lactamase inhibitors  
New carboxyphenyl-glycylboronic acid transition-state analog inhibitors, representative of a class of compounds effective against class C β-lactamase AmpC. The new compounds improve inhibition by...
US20090318711 Non-Covalent Inhibitors of AmpC ß-Lactamase  
β-lactamases are the most widespread resistance mechanism to β-lactam antibiotics, such as penicillins and cephalosporins. In response to these enzymes, inhibitors have been introduced....
7541381 Non-covalent inhibitors of AmpC β-lactamase  
β-lactamases are the most widespread resistance mechanism to β-lactam antibiotics, such as penicillins and cephalosporins. In response to these enzymes, inhibitors have been introduced....
WO/2007/053189A3 COMPOSITIONS AND METHODS FOR ALTERING IMMUNE FUNCTION  
The present invention relates to molecules that stabilize and/or enhance CD 154 activity, compositions comprising these molecules, methods for using these molecules and compositions (e.g.,...
7271186 Nanomolar β-lactamase inhibitors  
New carboxyphenyl-glycylboronic acid transition-state analog inhibitors, representative of a class of compounds effective against class C β-lactamase AmpC. The new compounds improve inhibition by...
WO/2007/053189A2 COMPOSITIONS AND METHODS FOR ALTERING IMMUNE FUNCTION  
The present invention relates to molecules that stabilize and/or enhance CD 154 activity, compositions comprising these molecules, methods for using these molecules and compositions (e.g.,...
US20050245498 Sterically-awkward beta-lactamase inhibitors  
Sterically-awkward 6-β-substituted P-lactam compounds as inhibitors of β-lactamase activity, such compounds as can be used in conjunction with one or more β-lactam antibiotics in a system for...
6887658 Methods of identifying non-specific inhibitors of biomolecules  
The present invention provides methods of identifying compounds that non-specifically inhibit biological reactions. The present invention further includes kits that facilitate this identification....
WO/2004/037163A3 STERICALLY-AWKWARD beta-LACTAMASE INHIBITORS  
6(7)-beta-substituted beta-lactam compounds as inhibitors of beta-lactamase activity.
US20040234942 METHODS OF IDENTIFYING NON-SPECIFIC INHIBITORS OF BIOMOLECULES  
The present invention provides methods of identifying compounds that non-specifically inhibit biological reactions. The present invention further includes kits that facilitate this identification....
WO/2004/037163A2 STERICALLY-AWKWARD β-LACTAMASE INHIBITORS  
6(7)-β-substituted β-lactam compounds as inhibitors of β-lactamase activity.
US20030236243 Sterically-awkward beta-lactamase inhibitors  
6(7)-β-substituted β-lactam compounds as inhibitors of β-lactamase activity.
US20030232830 Non-covalent inhibitors of AmpC beta-lactamase  
β-lactamases are the most widespread resistance mechanism to β-lactam antibiotics, such as penicillins and cephalosporins. In response to these enzymes, inhibitors have been introduced....
WO/2003/070682A1 NON-COVALENT INHIBITORS OF AmpC ß-LACTAMASE  
ß-lactamases are the most widespread resistance mechanism to ß-lactam antibiotics, such as penicillins and cephalosporins. In response to these enzymes, inhibitors have been introduced....
6448238 Inhibitors of β-lactamases and uses therefor  
The invention provides novel non-β-lactam inhibitors of β-lactamases. In particular, the invention provides such inhibitors which are boronic acids of formula (1) which is set forth in the...
WO/2002/022137A1 $g(b)-LACTAM ANALOGS AND USES THEREFOR  
The invention provides a method of treating a $g(b)-lactam-antibiotic-resistant bacterial infection with a combination of a $g(b)-lactamanalog. The invention also provides a method of inhibiting a...
6184363 Inhibitors of β-lactamases and uses therefor  
The invention provides novel non-β-lactam inhibitors of β-lactamases. In particular, the invention provides such inhibitors which are boronic acids of formula (1) which is set forth in the...
EP1009415A4 INHIBITORS OF $g(b)-LACTAMASES AND USES THEREFOR  
WO/2000/035905A1 INHIBITORS OF $g(b)-LACTAMASES AND USES THEREFOR  
The invention provides novel non-$g(b)-lactam inhibitors of $g(b)-lactamases. In particular, the invention provides such inhibitors which are boronic acids of formula (1) which is set forth in the...
WO/2000/035904A1 INHIBITORS OF $g(b)-LACTAMASES AND USES THEREFOR  
The invention provides novel non-$g(b)-lactam inhibitors of $g(b)-lactamases. In particular, the invention provides such inhibitors which are boronic acids of formula (1) which is set forth in the...
EP1009415A1 INHIBITORS OF $g(b)-LACTAMASES AND USES THEREFOR  
WO/1998/056392A1 INHIBITORS OF $g(b)-LACTAMASES AND USES THEREFOR  
The invention provides novel non-$g(b)-lactam inhibitors of $g(b)-lactamases. In particular, the invention provides such inhibitors which are boronic acids of formula (1) which is set forth in the...


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