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7425337 |
Alphavirus replicon vector systems
The present invention provides compositions useful in and methods for producing populations of infectious, replication-defective alphavirus replicon particles that contain no replication competent...
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7419674 |
Alpha virus-based cytomegalovirus vaccines
The present invention provides methods and compositions comprising a population of alphavirus replicon particles comprising alphavirus replicon RNAs, wherein a first replicon RNA comprises nucleic...
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7342002 |
Molecular vaccine linking an endoplasmic chaperone polypeptide to an antigen
This invention provides compositions and methods for inducing and enhancing immune responses, such as antigen-specific cytotoxic T lymphocyte (CTL) responses, using chimeric molecules comprising...
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7235235 |
Alphavirus RNA replicon systems
The present invention provides a helper cell for expressing an infectious, replication defective, alphavirus particle in an alphavirus-permissive cell. The helper cell includes (a) a first helper...
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7045335 |
Alphavirus replicon vector systems
The present invention provides compositions useful in and methods for producing populations of infectious, replication-defective alphavirus replicon particles that contain no replication-competent...
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6982087 |
Vectors derived from South African Arbovirus No. 86
Provided herein are alphavirus vectors derived from South African Arbovirus No. 86 (S.A.AR86) comprising attenuating mutations and methods of making the same. Also provided are improved viral...
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