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7380477 Method for tissue osmometry  
A measurement system including a staging unit including a substrate having piezoelectric properties and a conductive electrode formed on the substrate, the conductive electrode including an area...
7378280 Apparatus and methods for conducting assays and high throughput screening  
The present invention provides microfluidic devices and methods for using the same. In particular, microfluidic devices of the present invention are useful in conducting a variety of assays and...
7364647 Laminated flow device  
A laminated flow device comprises a porous material encapsulated within bonding material. The porous material forms a flow path and the bonding material forms an enclosure surrounding the flow...
7358099 Process for (A) separating biological/ligands from dilute solutions and (B) conducting an immunochromatographic assay thereof employing superparamagnetic particles throughout  
Superparamagnetic (“SPM”) subunits of 1–30 nm average mean diameter (e.g. ferro fluid) subparticles are treated with a magnetically noninterfering substance capable of coating and covering...
7351376 Integrated active flux microfluidic devices and methods  
The invention relates to a microfabricated device for the rapid detection of DNA, proteins or other molecules associated with a particular disease. The devices and methods of the invention can be...
7347976 Methods and devices for removal of organic molecules from biological mixtures using a hydrophilic solid support in a hydrophobic matrix  
Methods and devices for removing small negatively charged molecules from a biological sample mixture that uses a solid-phase extraction material that includes a hydrophilic solid support at least...
7332130 Heat-reduction methods and systems related to microfluidic devices  
A system and method for preventing or reducing unwanted heat in a microfluidic of the device while generating heat in selected regions of the device. In one example, current is supplied to a...
7329388 Electrophoresis apparatus having staggered passage configuration  
An electrophoresis apparatus is generally disclosed for sequentially analyzing a single sample or multiple samples having one or more analytes in high or low concentrations. The apparatus comprises...
7323140 Moving microdroplets in a microfluidic device  
The present invention relates to a system and method for moving samples, such as fluid, within a microfluidic system using a plurality of gas actuators for applying pressure at different locations...
7322254 Variable valve apparatus and methods  
Sample processing devices with variable valve structures and methods of using the same are disclosed. The valve structures allow for removal of selected portions of the sample material located...
7318902 Laminar flow-based separations of colloidal and cellular particles  
A system, method and apparatus employing the laminar nature of fluid flows in microfluidic flow devices in separating, sorting or filtering colloidal and/or cellular particles from a suspension in...
7306924 Biosensor and related method  
A method for collecting a microbiological substance utilizes a micro fabricated biochip having a collection chamber. A fluid sample containing a microbiological entity of interest is delivered to...
7276170 Laminar flow-based separations of colloidal and cellular particles  
A system, method and apparatus employing the laminar nature of fluid flows in microfluidic flow devices in separating, sorting or filtering colloidal and/or cellular particles from a suspension in...
7270786 Methods and systems for processing microfluidic samples of particle containing fluids  
The present invention relates to a microfluidic system for processing a cell-containing liquid. The system includes a microfabricated substrate having an enrichment channel to prepare an enriched...
7267753 Electrokinetic device having capacitive electrodes  
An electrokinetic device is capable of operating for extended periods of time, e.g. days to a week, without producing significant gaseous byproducts and without significant evolution of the pump...
7241421 Miniaturized fluid delivery and analysis system  
The present invention provides a method for combining a fluid delivery system with an analysis system for performing immunological, chemical, or biological assays. The method provides a miniature...
7241419 Circuits for the control of output current in an electronic device for performing active biological operations  
A circuit for control of an output current in a multiple unit cell array includes an array of unit cells arranged in rows and columns. Each unit cell includes a column select transistor being...
7235164 Electrokinetic pump having capacitive electrodes  
An electrokinetic pump achieves high and low flow rates without producing significant gaseous byproducts and without significant evolution of the pump fluid. A first feature of the pump is that the...
7235163 Loading features for channel array  
Apparatus and method for loading a channel device for electrophoretic separation including cilia which can be deflected into wells of a multi-well tray.
7226562 Liquid analysis cartridge  
The present invention provides an apparatus and method for storing a particle-containing liquid. The storage apparatus comprises a microfluidic convoluted flow channel having a plurality of...
7214322 ***WITHDRAWN PATENT AS PER THE LATEST USPTO WITHDRAWN LIST***
Laminar flow-based separations of colloidal and cellular particles  
A system, method and apparatus employing the laminar nature of fluid flows in microfluidic flow devices in separating, sorting or filtering colloidal and/or cellular particles from a suspension in...
7211184 Capillary electrophoresis devices  
A capillary electrophoresis device as well as a process for fabrication of the device is disclosed. The capillary electrophoresis device comprises a device body structure having a plurality of...
EP1777298A1 Multiplexed solid-phase nucleic acid amplification assay  
The present invention provides methods for detecting the amplification of a target nucleic acid using an oligonucleotide probe immobilized onto a solid substrate via its 3'-end. The invention...
7192560 Methods and devices for removal of organic molecules from biological mixtures using anion exchange  
Methods and devices for removing small negatively charged molecules from a biological sample mixture that uses an anion exchange material.
7192557 Methods and systems for releasing intracellular material from cells within microfluidic samples of fluids  
The present invention relates to a microfluidic system for processing a cell-containing liquid. The system includes a lysing zone to receive the cell-containing sample and a positioning element to...
7172896 Integrated portable biological detection system  
We have performed separation of bacterial and cancer cells from peripheral human blood in microfabricated electronic chips by dielectrophoresis. The isolated cells were examined by staining the...
7163612 Method, apparatus and article for microfluidic control via electrowetting, for chemical, biochemical and biological assays and the like  
An active matrix microfluidic platform employs thin film transistor active (“TFT”) matrix liquid crystal display technology to manipulate small samples of fluid for chemical, biochemical, or...
7157049 Optical bio-discs and fluidic circuits for analysis of cells and methods relating thereto  
The present invention is directed to optical bio-discs, methods, and optical disc drives for clinical diagnostics. The present invention is further directed to methods for determining the quantity...
7156969 Microfluidic matrix localization apparatus and methods  
Multiphasic microfluidic apparatus for performing product fluid manipulation and separation in a single continuous unit are provided. Related methods, kits, and compositions are also provided.
7153407 Multi-dimensional electrophoresis apparatus  
An electrophoresis apparatus is generally disclosed for sequentially analyzing a single sample or multiple samples having one or more analytes in high or low concentrations. The apparatus comprises...
7147764 Dual electrode injection of analyte into a capillary electrophoretic device  
An injection system including a first electrical circuit for concentration of an analyte and a second electrical circuit for injection of the concentrated analyte into an electrophoretic device is...
7118910 Microfluidic device and methods of using same  
A variety of elastomeric-based microfluidic devices and methods for using and manufacturing such devices are provided. Certain of the devices have arrays of reaction sites to facilitate high...
7010391 Methods and systems for control of microfluidic devices  
The present invention provides control methods, control systems, and control software for microfluidic devices that operate by moving discrete micro-droplets through a sequence of determined...
6969454 Apparatus for the location and concentration of polar analytes using an alternating electric field  
A method is disclosed for effecting the concentration of a polar analyte in an alternating electric field. In the method, a relative translation of the polar analyte and an alternating electric...
6960437 Nucleic acid amplification utilizing microfluidic devices  
The present invention provides microfluidic devices and methods using the same in various types of thermal cycling reactions. Certaom devices include a rotary microfluidic channel and a plurality...
6900021 Microfluidic system and methods of use  
This invention relates to a novel microfluidic device and methods of using this device to conduct in vitro studies on the reaction and effects of various compounds on cells. More particularly, it...
6852287 Microfluidic devices having a reduced number of input and output connections  
A system and method for reducing the number of input/output connections required to connect a microfluidic substrate to an external controller for controlling the substrate. In one example, a...
6852284 Liquid analysis cartridge  
The present invention provides an apparatus and method for storing a particle-containing liquid. The storage apparatus comprises a microfluidic convoluted flow channel having a plurality of article...
6846638 Method and system for rapid biomolecular recognition of amino acids and protein sequencing  
Methods, compositions, kits, and apparatus are provided wherein the aminoacyl-tRNA synthetase system is used to analyze amino acids. The method allows very small devices for quantitative or...
6833242 Methods for detecting and sorting polynucleotides based on size  
This invention relates in general to a method for molecular fingerprinting. The method can be used for forensic identification (e.g. DNA fingerprinting, especially by VNTR), bacterial typing, and...
6830729 Sample analysis instrument  
The present invention provides an apparatus and method for storing a particle-containing liquid. The storage apparatus comprises a microfluidic convoluted flow channel having a plurality of...
6802489 Micro-fluidic valve with a colloidal particle element  
The present invention relates to the use colloidal particles to realize photonic and microfluidic devices. In particular embodiments, colloidal particles are used to realize microfluidic a two-way...
6767706 Integrated active flux microfluidic devices and methods  
The invention relates to a microfabricated device for the rapid detection of DNA, proteins or other molecules associated with a particular disease. The devices and methods of the invention can be...
6730516 Microfluidic devices and methods  
Embodiments of the invention are directed to microfluidic devices. In one embodiment, a microanalysis chip comprises a body having at least one transfer-separation channel with a channel bottom...
6728429 Optical detection  
The invention features a waveguide based devices, methods, and systems to increase sensitivity of surface plasmon resonance (SPR) measurement through the use of differential detection. The enhanced...
6720157 Chips having elevated sample surfaces  
A chip is disclosed. The chip includes a base including a non-sample surface and at least one structure includes a pillar. Each structure includes a sample surface that is elevated with respect to...
6716620 Biosensor and related method  
A microscale biosensor for use in the detection of target biological substances including molecules and cells is a microfluidic system with integrated electronics, inlet-outlet ports and interface...
6712925 Method of making a liquid analysis cartridge  
The present invention provides an apparatus and method for storing a particle-containing liquid. The storage apparatus comprises a microfluidic convoluted flow channel having a plurality of...
6692700 Heat-reduction methods and systems related to microfluidic devices  
A system and method for preventing or reducing unwanted heat in a microfluidic of the device while generating heat in selected regions of the device. In one example, current is supplied to a...
6676819 Methods and apparatus for automatic on-line multi-dimensional electrophoresis  
The invention provides a method of performing one- and two-dimensional electrophoresis with or without gel in an automated way. The two dimensional electrophoresis can be performed either...
Matches 1 - 50 out of 66 1 2 >