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7381315 |
Multi-channel analyte-separation device employing side-entry excitation
A side-entry excitation arrangement is provided with a multi-channel analyte-separation device. In various embodiments, a plurality of channels are disposed in an array, with a laser disposed to...
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7329333 |
Uniform laser excitation and detection in capillary array electrophoresis system and method
A capillary electrophoresis system comprises capillaries positioned in parallel to each other forming a plane. The capillaries are configured to allow samples to migrate. A light source is...
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7280207 |
Time-delay integration in a flow cytometry system
An apparatus for detecting analytes in a sample is provided. The apparatus can include: a flow cytometry system including one or more detection zones; one or more irradiation sources disposed for...
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7265833 |
Electrophoretic system with multi-notch filter and laser excitation source
Apparatus and methods for detecting analytes in a sample are provided. The apparatus can include: one or more channels having a detection zone; one or more irradiation sources disposed for...
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7250098 |
Multi-capillary array electrophoresis device
An electrophoresis apparatus includes a multi-capillary array having a liquid or solid disposed between the capillaries of the array. The liquid or solid exhibits a refractive index higher than...
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7223326 |
Capillary electrophoresis system
A capillary electrophoresis system includes a plurality of capillaries arranged in parallel on a vertical plane at an identical distance from each other, each of which has a sample injection end...
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7189361 |
Analytical device with lightguide Illumination of capillary and microgrooves arrays
An analytical cell including a lightguide with a plurality of conduits filled with a migration medium. The medium, the lightguide and a surrounding medium have refractive indices selected such that...
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7123764 |
Image processing method for use in analyzing data of a chemotaxis or haptotaxis assay
An image processing method for use in analyzing image data of a cellular migration assay. The method includes defining a major axis within the image data that is perpendicular to an orientation of...
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7108775 |
Apparatus and method for confining eluted samples in electrophoresis systems
The present teachings provide a microfluidic apparatus comprising a body defining at least one channel that extends through said body, the channel including an inlet and an outlet; and an electrode...
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7054004 |
Capillary array and capillary array photodetector
A multi-focus capillary array that can reduce crosstalk and a capillary array photodetector are provided. On a substrate 20 on which a plurality of capillaries are aligned, a perforation 72 is...
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7019831 |
Separation device substrate including non-fluorescent quencher dye
A device is provided for the analysis of samples. The device includes a plurality of sample-containment features and a non-fluorescent quenching material for minimizing cross-talk between optical...
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6977034 |
Capillary array and electrophoresis apparatus
A capillary array comprising multiple capillaries and two holding substrates for arranging the aforementioned multiple capillaries in a substantially plane surface by sandwiching at least some of...
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6972183 |
Capillary array-based enzyme screening
A process for screening an expression library to identify clones expressing enzymes having a desired activity is provided. The process involves first generating from genomic DNA samples of one or...
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6913679 |
Apparatus and methods for high resolution separation of sample components on microfabricated channel devices
Sample component separation apparatus and methods are described. An exemplary sample component separation apparatus includes a separation channel having a turn portion configured to reduce...
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6866824 |
Capillary array-based sample screening
Provided are methods of screening and identification of bioactivities and bioactive molecules of interest using a capillary array system. More specifically, disclosed are methods of using optical...
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6856390 |
Time-delay integration in electrophoretic detection systems
An apparatus for detecting analytes in a sample is provided. The apparatus includes: one or more channels having a detection zone; one or more irradiation sources disposed for irradiating the...
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6808610 |
Capillary array electrophoresis apparatus
When irradiating laser beam from the side face of the capillary array, an optical axis of the laser beam is inclined in vertical direction with respect to a plane face formed by the capillary...
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6797139 |
Detection cell for guiding excitation light therein and method for using same
The present invention provides a detection cell that comprises a body having a first end that defines a first opening, a second end that defines a second opening, and an internal surface that...
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6794127 |
Capillary array-based sample screening
Provided are methods of screening and identification of bio activities and bioactive molecules of interest using a capillary array system. More specifically, disclosed are methods of using optical...
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6627433 |
Multi-channel analyte-separation device employing side-entry excitation
A side-entry excitation arrangement is provided with a multi-channel analyte-separation device. In various embodiments, a plurality of channels are disposed in an array, with a laser disposed to...
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6613212 |
Multiple capillary electrophoresis systems
The invention concerns a multiple capillary electrophoresis system including many juxtaposed capillaries, at least one source for transmitting a beam designed to excite the molecules present in its...
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6475361 |
Capillary electrophoresis apparatus having filling/refilling system and methods for use thereof
The present invention relates to an electrophoresis apparatus having a filling/refilling system and methods of using the same. The electrophoresis apparatus comprises a first buffer chamber...
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6301377 |
Gel electrophoresis image warping
A computer-implemented image processing method and apparatus for warping a plurality of gel electrophoresis images is provided. The method includes the steps of assigning tiepoints in a reference...
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6103199 |
Capillary electroflow apparatus and method
The present invention concerns an apparatus for conducting a microfluidic process. The apparatus comprises integral first and second plates. The first plate comprises an array of sample receiving...
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6103083 |
Capillary electrophoresis apparatus and method
The present invention relates to an electrophoresis apparatus having a plurality of capillaries arranged in a plane such that a curving contour is formed by the intersection points of each of the...
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6054032 |
Capillary electrophoresis array
A capillary electrophoresis array that includes: (a) a plurality of capillary tubes arranged adjacent each other in a generally longitudinal orientation, each of the tubes having an inlet end, and...
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